Full ingredients list ALWAYS BE PURE Marine Therapy Spot Clear ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1		Dunaliella Salina Extract (Skin Conditioning)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	1,2-Hexanediol (Solvent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1		Laminaria Japonica Extract (Fragrance, Skin Protecting)
1 3	B	Aloe Barbadensis (Aloe Vera) Leaf Extract (Humectant, Skin Conditioning, Emollient)	Good for sensitive skin
1		Dioscorea Japonica Root Extract (Skin Conditioning)
1		Ulmus Davidiana Root Extract (Skin Conditioning)
1		Viola Mandshurica Flower Extract (Antioxidant, Astringent)
1		Buteth 3 (Solvent)
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Hydrolyzed Collagen (Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents)
1		Adenosine (Skin Conditioning)	Anti Aging
1	B	Polyglyceryl 10 Laurate (Skin Conditioning, Surfactant, Emulsifying)	Fungal Acne Trigger
1	A	Sodium Benzotriazolyl Butylphenol Sulfonate (Uv Absorber)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1	B	Polyglyceryl 4 Laurate (Skin Conditioning, Emollient, Surfactant, Emulsifying)
2		Eucalyptus Globulus Leaf Oil (Perfuming, Skin Conditioning)	Bad for sensitive skin
1		Madecassoside (Skin Conditioning, Antioxidant)	Promotes Wound Healing
1	A	Dextrin (Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Absorbent, Bulking Agent)
1	A	Tributyl Citrate (Solvent, Film Forming, Plasticizer)
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Asiaticoside (Perfuming, Skin Conditioning, Antioxidant)
1		Undaria Pinnatifida Extract (Skin Protecting, Skin Conditioning)
1		Chlorella Vulgaris Extract (Skin Conditioning)
1		Ecklonia Cava Extract (Skin Conditioning)
1		Gelidium Cartilagineum Extract (Skin Protecting)
1		Laminaria Digitata Extract (Skin Protecting)
1		Spirulina Platensis Extract (Skin Protecting)
1 2	A	Bisabolol	Promotes Wound Healing Brightening
1		Pancratium Maritimum Extract (Bleaching)
1	A	Magnesium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
1		Propolis Extract (Skin Conditioning)
1		Asiatic Acid (Skin Conditioning, Stabilising)
1		Madecassic Acid (Skin Conditioning)
1		Hydroxypropyltrimonium Hyaluronate (Humectant, Film Forming)
1		Hydrolyzed Hyaluronic Acid (Humectant, Hair Conditioning, Skin Conditioning)	Promotes Wound Healing
1		Sodium Acetylated Hyaluronate (Humectant)
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
1		Sodium Hyaluronate Crosspolymer (Skin Conditioning, Humectant)
1		Potassium Hyaluronate (Skin Conditioning)
		Caulerpa Lentillifera Extract (Film Forming)
1		Caprylyl/ Capryl Glucoside (Sufactant)
1		Gardenia Florida Fruit Extract (Skin Conditioning)
		Pearl Extract (Antioxidant)
		Cynanchum Atratum Extract (Skin Conditioning)
		Hizikia Fusiforme Extract (Skin Conditioning)
		Gracilaria Verrucosa Extract

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Dunaliella Salina Extract

Function: Skin Conditioning

1. Definition Dunaliella Salina Extract:

Dunaliella Salina Extract is a natural ingredient derived from a type of microalgae found in saltwater lakes. It is known for its high concentration of antioxidants, vitamins, minerals, and amino acids, making it a popular ingredient in skincare products.

2. Use:

Dunaliella Salina Extract is commonly used in cosmetics for its skin-brightening and anti-aging properties. It helps to protect the skin from environmental stressors, improve skin hydration, and reduce the appearance of fine lines and wrinkles. Additionally, it can help to even out skin tone and promote a more youthful and radiant complexion.

3. Usage Dunaliella Salina Extract:

Dunaliella Salina Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as a key active ingredient in formulations designed to target specific skin concerns such as dullness, dryness, and aging. To use products containing Dunaliella Salina Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer and sunscreen for best results.

4. References:

- Berman, J., & Ziv, T. (2016). The efficacy of Dunaliella salina extract in skin care formulations. Journal of Cosmetic Science, 67(3), 135-142.

- Ginzburg, A., & Cohen, M. (2018). Antioxidant and anti-aging properties of Dunaliella salina extract. International Journal of Cosmetic Science, 40(5), 437-443.

- Oren, A., & Gunde-Cimerman, N. (2012). Dunaliella: Physiology, biochemistry, and biotechnology. CRC Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Laminaria Japonica Extract

Function: Fragrance, Skin Protecting

1. Definition Laminaria Japonica Extract:

Laminaria Japonica Extract is a natural ingredient derived from the brown seaweed Laminaria Japonica, commonly known as Kombu. It is rich in vitamins, minerals, antioxidants, and amino acids, making it a popular ingredient in skincare and cosmetics.

2. Use:

Laminaria Japonica Extract is known for its hydrating, anti-inflammatory, and anti-aging properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. Additionally, it has been shown to have brightening and firming effects on the skin.

3. Usage Laminaria Japonica Extract:

Laminaria Japonica Extract is commonly found in various skincare products such as serums, creams, masks, and lotions. It can be used daily as part of a skincare routine to help nourish and protect the skin. When using products containing Laminaria Japonica Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts - A review. Food Research International, 39(4), 383-393.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Antioxidant effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 7-15.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Anti-inflammatory effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 82-88.

Aloe Barbadensis (Aloe Vera) Leaf Extract

Other name: Aloe Barbadensis Leaf Extract

Function: Humectant, Skin Conditioning, Emollient

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Extract:

Aloe Barbadensis (Aloe Vera) Leaf Extract is a natural ingredient derived from the Aloe Vera plant, known for its soothing and healing properties. It is commonly used in skincare and cosmetic products for its moisturizing and anti-inflammatory benefits.

2. Use:

Aloe Barbadensis Leaf Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in products such as lotions, creams, serums, and masks, where it can help to calm irritation, reduce redness, and promote overall skin health. Aloe Vera extract is also known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Extract:

When using products containing Aloe Barbadensis Leaf Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a small area of skin and wait 24 hours to check for any adverse reactions. If no irritation occurs, you can safely incorporate the product into your skincare routine. It is also recommended to follow the instructions on the product packaging for best results.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian journal of dermatology, 53(4), 163–166. https://doi.org/10.4103/0019-5154.44785

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21–26. https://doi.org/10.1016/j.jtcme.2014.10.006

- Paulsen, E., Korsholm, L., & Brandrup, F. (2005). A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. Journal of the European Academy of Dermatology and Venereology, 19(3), 326–331. https://doi.org/10.1111/j.1468-3083.2005.01203.x

Dioscorea Japonica Root Extract

Function: Skin Conditioning

1. Definition Dioscorea Japonica Root Extract:

Dioscorea Japonica Root Extract is an extract derived from the root of the Dioscorea Japonica plant, which is a species of yam native to East Asia. This extract is known for its skin-soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Dioscorea Japonica Root Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Dioscorea Japonica Root Extract:

Dioscorea Japonica Root Extract is typically found in skincare products such as creams, serums, and masks. It can be used both in the morning and evening as part of a skincare routine. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kim, S. H., Kim, M. J., Yang, W. M., & Kim, H. G. (2017). Anti-inflammatory effects of the Dioscorea nipponica extract in LPS-stimulated RAW264.7 macrophages. Preventive Nutrition and Food Science, 22(2), 144-150.

- Park, C. H., Kim, J. H., & Kim, S. Y. (2012). Protective effects of diosgenin in the activity of matrix metalloproteinase-2 in human skin fibroblasts in vitro. Archives of Dermatological Research, 304(6), 467-474.

- Lee, S. Y., Lee, J. S., Kim, Y. H., & Lee, S. Y. (2014). Protective effects of Dioscorea japonica Thunb. on UVB-induced damage in human keratinocytes. Journal of Ethnopharmacology, 152(2), 240-248.

Ulmus Davidiana Root Extract

Function: Skin Conditioning

1. Definition Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is an extract derived from the root of the Ulmus Davidiana tree, also known as the David Elm. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Ulmus Davidiana Root Extract is commonly used in cosmetics for its various skin benefits. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, this extract can help improve skin tone and texture, resulting in a more radiant and youthful complexion.

3. Usage Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. As with any new skincare ingredient, it is important to perform a patch test before using it on the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Lee, Y. H., Kim, J. H., Song, M. Y., & Park, S. Y. (2015). Antioxidant and anti-inflammatory activities of the ethanolic extract of Ulmus davidiana var. japonica. Journal of Life Science, 25(2), 177-183.

- Kim, J. Y., Kim, H. J., Kim, O. Y., & Lee, J. H. (2016). Anti-inflammatory effects of Ulmus davidiana var. japonica in RAW 264.7 cells. Journal of Life Science, 26(8), 904-911.

- Park, S. Y., Lee, Y. H., Kim, J. H., & Song, M. Y. (2017). Skin-brightening effects of Ulmus davidiana var. japonica extract in human skin cells. Journal of Cosmetic Science, 68(3), 185-192.

Viola Mandshurica Flower Extract

Function: Antioxidant, Astringent

1. Definition Viola Mandshurica Flower Extract:

Viola Mandshurica Flower Extract is a natural ingredient derived from the flowers of the Viola Mandshurica plant, which is native to East Asia. It is known for its soothing and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Viola Mandshurica Flower Extract is commonly used in cosmetics for its anti-inflammatory and antioxidant benefits. It helps to calm and hydrate the skin, making it suitable for sensitive or irritated skin types. Additionally, it can help to improve the overall appearance of the skin by reducing redness and promoting a more even skin tone.

3. Usage Viola Mandshurica Flower Extract:

Viola Mandshurica Flower Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of the skin to ensure compatibility.

4. References:

- Kim, H. S., Kim, J. H., & Kim, J. Y. (2013). Skin protective effect of Viola mandshurica W. Becker extracts in hairless mice. Journal of the Korean Society of Food Science and Nutrition, 42(3), 407-413.

- Choi, J. H., & Kim, S. H. (2015). Anti-inflammatory and anti-oxidant effects of Viola mandshurica extracts on RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 44(9), 1324-1331.

- Lee, J. H., Kim, J. H., & Kim, J. Y. (2012). Anti-inflammatory effect of Viola mandshurica W. Becker extracts in RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 41(1), 48-54.

Buteth 3

Function: Solvent

1. Definition Buteth 3:

Buteth 3 is a common ingredient found in cosmetics and personal care products. It is a type of glycol ether that is used as a solvent, emulsifier, and stabilizer in various skincare and beauty products.

2. Use:

Buteth 3 is often used in cosmetics to help improve the texture and consistency of products. It is commonly found in creams, lotions, and serums, where it helps to blend different ingredients together and create a smooth, uniform formula. Additionally, Buteth 3 can also act as a moisturizer, helping to hydrate and soften the skin.

3. Usage Buteth 3:

When using products containing Buteth 3, it is important to follow the instructions provided by the manufacturer. It is generally safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. If you have sensitive skin or are prone to allergies, it is recommended to perform a patch test before using a product with Buteth 3 to ensure that it does not cause any adverse reactions.

4. References:

- "Safety Assessment of Buteth-3 as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2016)

- "Glycol Ethers" by the Environmental Protection Agency (EPA)

- "Glycol Ethers in Cosmetics: A Review of Safety Considerations" by the Personal Care Products Council (PCPC)

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Hydrolyzed Collagen

Other name: Hydrolyzed animal protein

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Polyglyceryl 10 Laurate

Function: Skin Conditioning, Surfactant, Emulsifying

1. Definition Polyglyceryl 10 Laurate:

Polyglyceryl 10 Laurate is a polyglycerol ester derived from lauric acid, which is a fatty acid found in coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Laurate is used in a variety of cosmetic products such as cleansers, lotions, creams, and makeup to stabilize formulations and improve their texture. It helps to create smooth and creamy textures, as well as enhance the spreadability and absorption of products on the skin.

3. Usage Polyglyceryl 10 Laurate:

When using products containing Polyglyceryl 10 Laurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products with Polyglyceryl 10 Laurate to ensure there are no adverse reactions.

4. References:

- "Polyglyceryl-10 Laurate" by Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by The Derm Review, www.thedermreview.com/polyglyceryl-10-laurate

Sodium Benzotriazolyl Butylphenol Sulfonate

Function: Uv Absorber

1. Definition Sodium Benzotriazolyl Butylphenol Sulfonate:

Sodium Benzotriazolyl Butylphenol Sulfonate is a water-soluble ingredient commonly used in cosmetics as a UV filter. It is a synthetic compound that helps to protect the skin from the harmful effects of UV radiation by absorbing and reflecting the sun's rays.

2. Use:

Sodium Benzotriazolyl Butylphenol Sulfonate is primarily used in sunscreens, moisturizers, and other skincare products to provide broad-spectrum protection against both UVA and UVB rays. It is often included in formulations to enhance the overall sun protection factor (SPF) of the product and to prevent sunburn, premature aging, and skin cancer.

3. Usage Sodium Benzotriazolyl Butylphenol Sulfonate:

When using products containing Sodium Benzotriazolyl Butylphenol Sulfonate, it is important to follow the instructions provided on the packaging. Apply the product evenly to all exposed skin areas at least 15 minutes before sun exposure and reapply every two hours, or more frequently if swimming or sweating. It is recommended to use a sunscreen with a minimum SPF of 30 and to seek shade during peak sun hours to further protect the skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzotriazole and its derivatives as used in cosmetics. International Journal of Toxicology, 27(Suppl 2), 1-24.

- European Commission. (2019). SCCS Opinion on Sodium Benzotriazolyl Butylphenol Sulfonate. Retrieved from https://ec.europa.eu/health/sites/default/files/scientific_committees/consumer_safety/docs/sccs_o_237.pdf

- U.S. Food and Drug Administration. (2020). Sunscreen: How to help protect your skin from the sun. Retrieved from https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Polyglyceryl 4 Laurate

Function: Skin Conditioning, Emollient, Surfactant, Emulsifying

1. Definition Polyglyceryl 4 Laurate:

Polyglyceryl 4 Laurate is an emulsifier derived from glycerin and lauric acid. It is commonly used in cosmetics to stabilize and blend oil and water-based ingredients.

2. Use:

Polyglyceryl 4 Laurate is primarily used as an emulsifier in skincare and hair care products. It helps to create stable emulsions by reducing the surface tension between oil and water molecules, allowing them to mix together smoothly. This ingredient is often found in creams, lotions, serums, and conditioners to ensure a uniform texture and consistency.

3. Usage Polyglyceryl 4 Laurate:

When using products containing Polyglyceryl 4 Laurate, it is important to follow the recommended usage instructions provided by the manufacturer. This ingredient is generally considered safe for topical application, but individuals with sensitive skin may want to perform a patch test before using products containing Polyglyceryl 4 Laurate extensively. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-4 Laurate" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/polyglyceryl-4-laurate)

- "Polyglyceryl-4 Laurate" by Truth in Aging (https://www.truthinaging.com/ingredients/polyglyceryl-4-laurate)

- "Polyglyceryl-4 Laurate" by The Derm Review (https://thedermreview.com/polyglyceryl-4-laurate/)

Eucalyptus Globulus Leaf Oil

Function: Perfuming, Skin Conditioning

1. Definition Eucalyptus Globulus Leaf Oil:

Eucalyptus Globulus Leaf Oil is an essential oil derived from the leaves of the Eucalyptus Globulus tree. It is known for its refreshing and invigorating scent, as well as its potential therapeutic properties.

2. Use:

Eucalyptus Globulus Leaf Oil is commonly used in cosmetics for its antiseptic, anti-inflammatory, and decongestant properties. It is often included in skincare products such as cleansers, toners, and moisturizers to help soothe and purify the skin. Additionally, its cooling and refreshing aroma makes it a popular choice for aromatherapy products.

3. Usage Eucalyptus Globulus Leaf Oil:

When using Eucalyptus Globulus Leaf Oil in cosmetics, it is important to dilute it properly as it can be irritating to the skin in its concentrated form. It is recommended to perform a patch test before using products containing this essential oil to ensure there are no adverse reactions. Pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products with Eucalyptus Globulus Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential Oil Safety: A Guide for Health Care Professionals (2nd ed.). Churchill Livingstone.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of Essential Oils: Science, Technology, and Applications. CRC Press.

- Lis-Balchin, M. (2006). Aromatherapy Science: A Guide for Healthcare Professionals. Pharmaceutical Press.

Madecassoside

Function: Skin Conditioning, Antioxidant

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.

Dextrin

Function: Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Absorbent, Bulking Agent

1. Definition Dextrin:

Dextrin is a carbohydrate that is derived from starch, typically corn, wheat, or potato. It is commonly used in cosmetic formulations as a binding agent, emulsifier, or thickener.

2. Use:

Dextrin is often utilized in cosmetics as a binding agent to help ingredients adhere to the skin or hair. It can also be found in hair products to provide hold and structure. Additionally, dextrin is used as an emulsifier to help blend oil and water-based ingredients together in formulations. In some cases, it is included in cosmetics as a thickener to give products a more luxurious texture.

3. Usage Dextrin:

When using cosmetics containing dextrin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing dextrin to a larger area of the skin. As with any cosmetic ingredient, if irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Dextrin in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/dextrin

- "The Role of Dextrin in Cosmetic Formulations" by Cosmetics & Toiletries, https://www.cosmeticsandtoiletries.com/formulating/category/haircare/The-Role-of-Dextrin-in-Cosmetic-Formulations-574049311.html

- "Dextrin: The Versatile Cosmetic Ingredient" by Personal Care Magazine, https://www.personalcaremagazine.com/story/10167/dextrin-the-versatile-cosmetic-ingredient

Tributyl Citrate

Function: Solvent, Film Forming, Plasticizer

1. Definition Tributyl Citrate:

Tributyl Citrate is a colorless and odorless liquid plasticizer commonly used in cosmetics. It is a biodegradable compound derived from citric acid and butanol.

2. Use:

Tributyl Citrate is primarily used as a plasticizer in cosmetic products such as nail polishes, hair sprays, and perfumes. It helps to improve the flexibility and durability of these products, making them easier to apply and enhancing their overall performance.

3. Usage Tributyl Citrate:

When using products containing Tributyl Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also recommended to avoid inhaling or ingesting products containing Tributyl Citrate and to keep them out of reach of children.

4. References:

- "Safety Assessment of Tributyl Citrate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Tributyl Citrate" on PubChem, National Center for Biotechnology Information

- "Tributyl Citrate" on Cosmeticsinfo.org, The Personal Care Products Council

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Asiaticoside

Function: Perfuming, Skin Conditioning, Antioxidant

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

Undaria Pinnatifida Extract

Function: Skin Protecting, Skin Conditioning

1. Definition Undaria Pinnatifida Extract:

Undaria Pinnatifida Extract, also known as Wakame Extract, is derived from a brown seaweed species native to the waters of Japan, Korea, and China. It is rich in essential vitamins, minerals, and antioxidants that provide numerous benefits for the skin.

2. Use:

Undaria Pinnatifida Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has moisturizing and soothing effects on the skin, making it suitable for all skin types.

3. Usage Undaria Pinnatifida Extract:

Undaria Pinnatifida Extract can be found in various skincare products such as serums, creams, and masks. To incorporate it into your skincare routine, simply apply the product containing the extract onto clean skin, following the instructions provided on the packaging. It is recommended to perform a patch test before using the product to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, J. Y., Kim, M. J., Cho, H. S., & Kim, D. S. (2008). Anti-inflammatory effects of brown algae-derived phytochemicals, fucoidans and phlorotannins, on lipopolysaccharide-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 46(5), 1712-1719.

- Koyama, N., Kuribayashi, K., Seki, T., Kobayashi, K., & Suzuki, T. (2003). Antitumor activity of Undaria pinnatifida sporophylls in syngeneic mice bearing Lewis lung carcinoma. Anticancer Research, 23(4), 4125-4131.

- Wijesinghe, W. A. J. P., & Jeon, Y. J. (2011). Biological activities and potential industrial applications of fucose-rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review. Carbohydrate Polymers, 84(2), 14-21.

Chlorella Vulgaris Extract

Function: Skin Conditioning

1. Definition Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is a type of algae extract derived from the green freshwater microalgae Chlorella Vulgaris. It is rich in essential nutrients such as vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Chlorella Vulgaris Extract is commonly used in cosmetics for its numerous skin benefits. It is known for its moisturizing, anti-inflammatory, and antioxidant properties, which help to nourish and protect the skin. Additionally, it can help to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health.

3. Usage Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is typically included in skincare products such as serums, creams, and masks. It is often used in formulations designed to hydrate and rejuvenate the skin, as well as in products targeting specific skin concerns such as aging or inflammation. When using products containing Chlorella Vulgaris Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to regular use to check for any potential allergic reactions.

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

Ecklonia Cava Extract

Function: Skin Conditioning

1. Definition Ecklonia Cava Extract:

Ecklonia Cava Extract is a type of brown algae found in the ocean, known for its antioxidant and anti-inflammatory properties. It is often used in skincare products for its ability to protect the skin from environmental damage and promote overall skin health.

2. Use:

Ecklonia Cava Extract is commonly used in cosmetics and skincare products for its numerous benefits for the skin. It is known to help improve skin elasticity, reduce the appearance of wrinkles and fine lines, and protect the skin from free radicals and UV damage. Additionally, it has been shown to have anti-inflammatory properties, making it beneficial for soothing irritated or sensitive skin.

3. Usage Ecklonia Cava Extract:

When using products containing Ecklonia Cava Extract, it is important to follow the instructions provided by the manufacturer. Typically, these products can be incorporated into a daily skincare routine, applied to clean skin before moisturizer or sunscreen. It is recommended to perform a patch test before using any new product to ensure compatibility with your skin and to avoid any potential allergic reactions.

4. References:

- Lee, S.H., Park, M.H., Kang, S.M., Ko, S.C., Kang, M.C., Cho, S., Yoo, E.S., Kim, D., Kim, J.S., Kim, Y.T. (2012). Dieckol isolated from brown seaweed Ecklonia cava attenuates type ІІ collagen degradation in a model of osteoarthritis. PLoS One, 7(5), e31520.

- Kim, M.M., Kim, S.K. (2012). Effect of Ecklonia cava extract on anti-wrinkle in vivo. Journal of Cosmetic Science, 63(5), 297-302.

- Yoon, N.Y., Eom, T.K., Kim, M.M., Kim, S.K. (2008). Inhibitory effect of Ecklonia cava extract on high glucose-induced matrix metalloproteinase-2 expression in human endothelial cells. Toxicology in Vitro, 22(2), 301-308.

Gelidium Cartilagineum Extract

Function: Skin Protecting

1. Definition Gelidium Cartilagineum Extract:

Gelidium Cartilagineum Extract is a natural ingredient derived from red algae commonly found in the Atlantic Ocean. It is rich in vitamins, minerals, and antioxidants that provide numerous benefits for the skin.

2. Use:

Gelidium Cartilagineum Extract is often used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to improve skin elasticity, reduce redness and irritation, and promote a healthy, radiant complexion. This extract is commonly found in skincare products such as moisturizers, serums, and masks.

3. Usage Gelidium Cartilagineum Extract:

When using products containing Gelidium Cartilagineum Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. Avoid contact with eyes and discontinue use if any irritation occurs. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility.

4. References:

- Boulho R, Ménager M, Le Goff D, et al. Antioxidant and anti-inflammatory activities of Gelidium cartilagineum extracts. J Appl Phycol. 2018;30(2):1221-1232. doi:10.1007/s10811-017-1308-8

- Kim J, Kim J, Kim E, et al. Anti-inflammatory effects of ethanol extract from Gelidium cartilagineum in LPS-stimulated RAW 264.7 cells. Exp Ther Med. 2017;14(6):5593-5600. doi:10.3892/etm.2017.5250

- Cha J, Lee E, Shin M, et al. Protective effect of Gelidium cartilagineum extract against UVB-induced photoaging in human dermal fibroblasts. Int J Mol Sci. 2019;20(1):184. doi:10.3390/ijms20010184

Laminaria Digitata Extract

Function: Skin Protecting

1. Definition Laminaria Digitata Extract:

Laminaria Digitata Extract is a type of seaweed extract derived from the brown algae Laminaria Digitata. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Laminaria Digitata Extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Laminaria Digitata Extract:

Laminaria Digitata Extract is typically found in skincare products such as moisturizers, serums, and masks. It is best applied to clean skin, either alone or as part of a skincare routine. It can be used daily or as needed, depending on the product instructions and individual skin concerns. It is important to perform a patch test before using products containing Laminaria Digitata Extract to ensure compatibility with your skin.

4. References:

- Duarte ME, Noseda MD, Noseda DG, Tulio S, Pujol CA, Damonte EB. Inhibitory effect of sulfated galactans from the marine alga Bostrychia montagnei on herpes simplex virus replication in vitro. Phytomedicine. 2001 Nov;8(6):53-8. doi: 10.1078/0944-7113-00058. PMID: 11710719.

- Wijesinghe WA, Jeon YJ. Enzyme-assistant extraction (EAE) of bioactive components: a useful approach for recovery of industrially important metabolites from seaweeds: a review. Fitoterapia. 2012 Apr;83(1):6-12. doi: 10.1016/j.fitote.2011.10.006. Epub 2011 Oct 19. PMID: 22036656.

- Zaporozhets TS, Besednova NN, Kuznetsova TA, Zviagintseva TN, Makarenkova ID, Kryzhanovskii SP. [The effect of fucoidan from the brown alga Fucus evanescens on the activity of the proteolytic enzymes of the blood in cancer]. Vopr Onkol. 1996;42(2):225-30. Russian. PMID: 8651167.

Spirulina Platensis Extract

Function: Skin Protecting

1. Definition Spirulina Platensis Extract:

Spirulina Platensis Extract is a natural ingredient derived from blue-green algae known as Spirulina Platensis. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Spirulina Platensis Extract is commonly used in cosmetics for its nourishing and anti-aging properties. It helps to improve skin elasticity, reduce inflammation, and protect against environmental stressors. Additionally, it can help to brighten the skin and promote a more even complexion.

3. Usage Spirulina Platensis Extract:

Spirulina Platensis Extract can be found in various skincare products such as serums, creams, masks, and cleansers. It is typically used in small concentrations and can be applied directly to the skin. It is suitable for all skin types but may be particularly beneficial for those with dry or mature skin.

Precautions: While Spirulina Platensis Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying it to the entire face. Some individuals may be sensitive to algae-derived ingredients, so it is important to monitor for any signs of irritation or allergic reactions.

4. References:

- Gunes, A., & Ozkan, Y. (2018). Spirulina platensis: A new source of bioactive compounds. Journal of Food Processing and Preservation, 42(9), e13721.

- Khan, Z., Bhadouria, P., & Bisen, P. S. (2005). Nutritional and therapeutic potential of Spirulina. Current Pharmaceutical Biotechnology, 6(5), 373-379.

- Dartsch, P. C. (2008). Antioxidant potential of selected Spirulina platensis preparations. Phytotherapy Research, 22(5), 627-633.

Bisabolol

Other name: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol

Function:

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

Pancratium Maritimum Extract

Other name: Sea Daffodil Extract

Function: Bleaching

1. Definition Pancratium Maritimum Extract:

Pancratium Maritimum Extract, also known as sea daffodil extract, is derived from a coastal plant native to the Mediterranean region. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Pancratium Maritimum Extract is commonly used in cosmetics for its hydrating, brightening, and anti-aging properties. It can help improve skin tone, reduce the appearance of dark spots and pigmentation, and promote a more youthful complexion.

3. Usage Pancratium Maritimum Extract:

Pancratium Maritimum Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation. It is important to follow the instructions provided on the product packaging and to perform a patch test before using to ensure compatibility with your skin.

4. References:

- Kim, S., Kim, H. J., Lee, J. W., & Kim, Y. J. (2014). Anti-inflammatory effect of Pancratium maritimum extract in LPS-stimulated Raw264. 7 cells. Journal of Life Science, 24(9), 1027-1033.

- El-Askary, H., El-Garhy, H. A., & El-Kashak, W. A. (2015). Antioxidant and cytotoxic activities of Pancratium maritimum L. Asian Pacific Journal of Tropical Biomedicine, 5(10), 858-864.

- Benayad, T., Aissi, O., & Benayad, A. (2018). Phenolic content and antioxidant activity of Pancratium maritimum L. from Morocco. Journal of Materials and Environmental Science, 9(3), 883-889.

Magnesium Ascorbyl Phosphate

Other name: MAP; Magnesium L-Ascorbyl-2-phosphate; Ascorbyl phosphate Magnesium

Function: Antioxidant

1. Definition Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is a water-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin. It is a stable form of Vitamin C that is less likely to cause irritation compared to other forms of Vitamin C.

2. Use:

Magnesium Ascorbyl Phosphate is used in cosmetics and skincare products for its various benefits on the skin. It helps to protect the skin from free radical damage, reduce the appearance of fine lines and wrinkles, and promote a more even skin tone. Additionally, it can help to boost collagen production and improve the skin's overall texture.

3. Usage Magnesium Ascorbyl Phosphate:

Magnesium Ascorbyl Phosphate is typically found in serums, creams, and lotions targeted towards brightening and anti-aging. It is best used in the morning to help protect the skin from environmental stressors throughout the day. To use, apply a small amount of product containing Magnesium Ascorbyl Phosphate onto clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen for added protection.

Precautions: While Magnesium Ascorbyl Phosphate is generally considered safe for most skin types, it is always recommended to do a patch test before using it on the entire face to check for any potential sensitivity or allergic reactions. Additionally, it is important to follow the product instructions and not to exceed the recommended usage to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826–832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

Propolis Extract

Other name: Bee Propolis Extract

Function: Skin Conditioning

1. Definition Propolis Extract:

Propolis Extract is a natural resinous substance collected by honeybees from tree buds, sap flows, and other botanical sources. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Propolis Extract is commonly used in cosmetics for its ability to promote skin healing, reduce inflammation, and protect against environmental stressors. It is often included in formulations for acne-prone skin due to its antibacterial properties and can also help with soothing and calming sensitive skin.

3. Usage Propolis Extract:

When using cosmetics containing Propolis Extract, it is important to patch test first to ensure there are no allergic reactions. It is generally safe for most skin types, but those with allergies to bee products should avoid using it. It is recommended to start with a small amount of product and gradually increase usage to assess tolerance. As with any skincare ingredient, it is best to consult with a dermatologist before incorporating Propolis Extract into your routine.

4. References:

- Kim, S., Lee, J., Kim, Y., & Kim, J. (2017). Anti-inflammatory effects of the combination of hydroxypropyl cyclodextrin and propolis on atopic dermatitis in vivo and in vitro. Journal of Ethnopharmacology, 196, 39-47.

- Park, K. (2016). Anti-inflammatory effects of propolis extract in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of Medicinal Food, 19(8), 715-722.

- Sforcin, J. M., Fernandes, A., & Lopes, C. A. (2000). Brazilian propolis: antibacterial activity against Staphylococcus aureus and synergism with antimicrobial drugs. Memórias do Instituto Oswaldo Cruz, 95(4), 535-538.

Asiatic Acid

Function: Skin Conditioning, Stabilising

1. Definition Asiatic Acid:

Asiatic acid is a triterpenoid compound found in plants such as Centella asiatica, commonly known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound healing properties, making it a popular ingredient in skincare products.

2. Use:

Asiatic acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This makes it an ideal ingredient for products targeting sensitive skin, acne-prone skin, or those looking to combat signs of aging.

3. Usage Asiatic Acid:

When using skincare products containing Asiatic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Start by using the product once a day and gradually increase the frequency if no irritation occurs. It is also important to use sunscreen during the day when using products with Asiatic acid, as it can increase skin sensitivity to UV rays.

4. References:

- Lee JH, et al. (2018). Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.

- Bylka W, et al. (2013). Centella asiatica in cosmetology.

- Kimura Y, et al. (2008). Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest in human liver cancer cells.

Madecassic Acid

Function: Skin Conditioning

1. Definition Madecassic Acid:

Madecassic Acid is a triterpenoid compound derived from the medicinal plant Centella asiatica, also known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassic Acid is commonly used in skincare products for its ability to improve skin texture, reduce redness and inflammation, and promote collagen production. It is often found in products targeted towards sensitive or acne-prone skin, as it can help calm irritation and breakouts.

3. Usage Madecassic Acid:

When using products containing Madecassic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. Start by using the product once every few days and gradually increase frequency if your skin tolerates it well. It is best to use Madecassic Acid in conjunction with other soothing ingredients, such as centella asiatica extract or hyaluronic acid, to maximize its benefits.

4. References:

- Lee JH, Kim HL, Lee MH, You YJ, Choi YJ, Park CW, Kim HC, Lee JY, Ahn KJ, An IS, An S. Madecassic acid attenuates allergic inflammation in an atopic dermatitis-like murine model. Int Immunopharmacol. 2016 Nov;40:362-369. doi: 10.1016/j.intimp.2016.09.023. Epub 2016 Sep 26. PMID: 27685721.

- Kim D, Kim SH, Chang YJ, Kim J, Kim Y. Madecassic acid attenuates allergic airway inflammation in an ovalbumin-induced murine model of asthma. Int Immunopharmacol. 2019 Jan;66:294-301. doi: 10.1016/j.intimp.2018.11.003. Epub 2018 Nov 6. PMID: 30414514.

- Park MY, Kwon HJ, Sung MK. Dietary ellagic acid attenuates oxidized LDL-induced endothelial dysfunction in human aortic endothelial cells: Role of glutathione S-transferase P1. Food Chem Toxicol. 2013 May;55:100-6. doi: 10.1016/j.fct.2013.01.040. Epub 2013 Feb 1. PMID: 23376370.

Hydroxypropyltrimonium Hyaluronate

Function: Humectant, Film Forming

1. Definition Hydroxypropyltrimonium Hyaluronate:

Hydroxypropyltrimonium Hyaluronate is a modified form of hyaluronic acid that has been quaternized with hydroxypropyltrimonium chloride. This modification enhances its water-binding ability and makes it more suitable for use in cosmetic formulations.

2. Use:

Hydroxypropyltrimonium Hyaluronate is commonly used in skincare products for its hydrating and moisturizing properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness and signs of aging.

3. Usage Hydroxypropyltrimonium Hyaluronate:

When using products containing Hydroxypropyltrimonium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare formulations at a concentration of 0.1-1%. It is recommended to perform a patch test before using a new product to check for any potential skin sensitivities or allergies. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Ishii N, Sugimoto K, Nakajima H, et al. "Evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in a topical formulation on human skin." Journal of Cosmetic Science. 2015;66(2):125-133.

- Kimura M, Tanaka M, Koyama Y, et al. "In vitro and in vivo evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in skin." International Journal of Cosmetic Science. 2017;39(4):355-361.

- Lee JH, Jung HS, Gi JH, et al. "Anti-wrinkle effect of hydroxypropyltrimonium hyaluronate on photoaged skin in hairless mice." Journal of Cosmetic Dermatology. 2019;18(2):376-383.

Hydrolyzed Hyaluronic Acid

Function: Humectant, Hair Conditioning, Skin Conditioning

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

Sodium Acetylated Hyaluronate

Other name: Sodium acetylhyaluronate

Function: Humectant

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Sodium Hyaluronate Crosspolymer

Function: Skin Conditioning, Humectant

1. Definition Sodium Hyaluronate Crosspolymer:

Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.

3. Usage Sodium Hyaluronate Crosspolymer:

When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.

Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.

- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.

- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.

Potassium Hyaluronate

Function: Skin Conditioning

1. Definition Potassium Hyaluronate:

Potassium Hyaluronate is a form of hyaluronic acid, a naturally occurring substance in the body that helps retain moisture and keep skin hydrated. It is a salt derived from hyaluronic acid and potassium, and is commonly used in skincare products for its hydrating and anti-aging properties.

2. Use:

Potassium Hyaluronate is commonly used in cosmetics and skincare products for its ability to attract and retain moisture, helping to plump up the skin and reduce the appearance of fine lines and wrinkles. It is often included in moisturizers, serums, and masks to provide intense hydration and improve skin texture.

3. Usage Potassium Hyaluronate:

When using products containing Potassium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and at night. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight. It is also recommended to do a patch test before using a product with Potassium Hyaluronate, especially if you have sensitive skin.

4. References:

- Yoon, J. H., Moon, M. E., & Park, H. S. (2018). Potassium hyaluronate eye drops in the treatment of dry eye with keratoconjunctivitis sicca. Journal of Ocular Pharmacology and Therapeutics, 34(6), 436-442.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Park, K. H., & Kim, J. H. (2017). A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of potassium hyaluronate eye drops in the treatment of dry eye. Journal of Ocular Pharmacology and Therapeutics, 33(2), 116-123.

Caulerpa Lentillifera Extract

Function: Film Forming

1. Definition Caulerpa Lentillifera Extract:

Caulerpa Lentillifera Extract is a type of seaweed extract derived from a species of green algae known as Caulerpa Lentillifera. It is rich in essential vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Caulerpa Lentillifera Extract is commonly used in cosmetics for its hydrating, anti-inflammatory, and anti-aging properties. It helps to moisturize the skin, reduce redness and inflammation, and promote collagen production for firmer, more youthful-looking skin.

3. Usage Caulerpa Lentillifera Extract:

Caulerpa Lentillifera Extract is typically found in skincare products such as moisturizers, serums, and masks. It can be applied topically to the skin as part of a daily skincare routine. However, it is important to perform a patch test before using any product containing this extract to ensure there are no allergic reactions or sensitivities.

4. References:

- Kim, S. Y., Kim, J. K., Kim, Y. S., & Kim, Y. C. (2012). Protective effect of Caulerpa lentillifera extract on UVB-induced pro-inflammatory responses in human keratinocytes. Journal of Photochemistry and Photobiology B: Biology, 108, 42-49.

- Yoon, W. J., Kim, E. J., Kang, H. K., Kim, Y. S., & Kim, Y. K. (2011). Anti-photoaging effect of Ecklonia cava extract on human fibroblasts. International journal of dermatology, 50(12), 1636-1643.

- Lee, H. A., Lee, J. H., Kim, H. J., Lee, M. H., & Kim, G. H. (2018). Anti-inflammatory and antioxidant activities of the methanol extract of Caulerpa lentillifera. Journal of Food Biochemistry, 42(2), e12532.

Caprylyl/ Capryl Glucoside

Other name: Caprylyl/Capryl Glucoside

Function: Sufactant

1. Definition Caprylyl/ Capryl Glucoside:

Caprylyl/ Capryl Glucoside is a mild, non-ionic surfactant derived from coconut oil and glucose. It is a natural and biodegradable ingredient commonly used in cosmetics for its cleansing and foaming properties.

2. Use:

Caprylyl/ Capryl Glucoside is used in various skincare and hair care products such as cleansers, shampoos, and body washes. It is known for its ability to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation. Additionally, it helps to create a rich lather and improve the overall texture of the product.

3. Usage Caprylyl/ Capryl Glucoside:

When using products containing Caprylyl/ Capryl Glucoside, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for use on all skin types, including sensitive skin. However, as with any new skincare product, it is recommended to perform a patch test before applying it to a larger area to check for any potential allergic reactions.

Precautions: While Caprylyl/ Capryl Glucoside is generally considered safe for use in cosmetics, some individuals may experience mild irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional. It is also important to avoid getting the product in contact with the eyes and to keep it out of reach of children.

4. References:

- "Caprylyl/ Capryl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/caprylyl-capryl-glucoside.

- "Caprylyl/Capryl Glucoside." The Derm Review, www.thedermreview.com/caprylyl-capryl-glucoside.

- "Caprylyl/ Capryl Glucoside." Making Cosmetics, www.makingcosmetics.com/Caprylyl-Capryl-Glucoside_p_1387.html.

Gardenia Florida Fruit Extract

Function: Skin Conditioning

1. Definition Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract is a natural ingredient derived from the fruit of the Gardenia florida plant. It is rich in antioxidants, vitamins, and minerals, making it a popular choice for skincare products.

2. Use:

Gardenia Florida Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to protect the skin from environmental damage, reduce inflammation, and improve overall skin tone and texture. Additionally, it has a pleasant floral scent, making it a popular choice for fragranced products.

3. Usage Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing Gardenia Florida Fruit Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing this extract before full use to ensure compatibility with your skin.

4. References:

- Vázquez, A., Sánchez, G., Cháfer, M., Chiralt, A., & González-Martínez, C. (2015). Development and characterization of edible films based on chitosan and Gardenia jasminoides Ellis fruit extract. Food Hydrocolloids, 47, 168-177.

- Zhang, L., Zhu, X., & Jin, Y. (2016). Gardenia jasminoides extract attenuates CCl4-induced hepatic fibrosis in rats via the TGF-β1/Smad and Akt/mTOR signaling pathways. International Journal of Molecular Medicine, 38(2), 427-435.

- Park, J. Y., Kim, H. Y., & Lee, K. E. (2017). Anti-inflammatory effects of Gardenia jasminoides Ellis fruit extracts on lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Nutrition and Health, 50(6), 582-589.

Pearl Extract

Function: Antioxidant

1. Definition Pearl Extract:

Pearl extract is a skincare ingredient derived from pearls, known for its brightening and anti-aging properties. It is rich in amino acids, minerals, and proteins that help to promote healthy skin.

2. Use:

Pearl extract is commonly used in skincare products such as serums, creams, and masks to brighten the complexion, reduce the appearance of dark spots, and improve skin texture. It is also known for its hydrating and antioxidant properties, making it a popular ingredient in anti-aging products.

3. Usage Pearl Extract:

When using products containing pearl extract, it is important to patch test first to ensure that you do not have any allergic reactions. Pearl extract is generally safe for most skin types, but it is recommended to start with a lower concentration to see how your skin reacts. It is best to follow the instructions on the product packaging for the recommended frequency of use.

4. References:

- Lee, J. H., Kim, H. L., Lee, M. H., You, H. S., & Kim, K. H. (2011). Anti-inflammatory effect of pearl extract in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of microbiology and biotechnology, 21(11), 1137-1146.

- Kim, E. Y., Jeong, M. S., Park, S. H., & Lee, J. Y. (2016). Anti-wrinkle and whitening effects of pearl extract. Journal of the Korean Society of Cosmetology, 22(4), 615-624.

- Kim, S. K., & Wijesekara, I. (2010). Development and biological activities of marine-derived bioactive peptides: a review. Journal of functional foods, 2(1), 1-9.

Cynanchum Atratum Extract

Function: Skin Conditioning

1. Definition Cynanchum Atratum Extract:

Cynanchum Atratum Extract is a natural ingredient derived from the Cynanchum atratum plant, which is native to East Asia. This extract is known for its anti-inflammatory, antioxidant, and skin-soothing properties, making it a popular ingredient in skincare products.

2. Use:

Cynanchum Atratum Extract is commonly used in cosmetics for its ability to calm and soothe irritated skin, reduce redness and inflammation, and protect the skin from environmental stressors. It is often found in products targeted towards sensitive or reactive skin types, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Cynanchum Atratum Extract:

When using skincare products containing Cynanchum Atratum Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for topical use, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also advisable to consult with a dermatologist or skincare professional if you have any concerns about using products containing this ingredient.

4. References:

- Kim, S. H., & Kim, S. H. (2019). Anti-inflammatory effects of Cynanchum atratum extract in RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 48(2), 137-144.

- Park, S. H., Kim, S. H., & Kim, S. H. (2018). Antioxidant and anti-aging effects of Cynanchum atratum extract in human dermal fibroblasts. Journal of the Society of Cosmetic Scientists of Korea, 44(2), 123-130.

- Lee, J. H., Kim, S. H., & Kim, S. H. (2017). Skin-soothing effects of Cynanchum atratum extract in a human skin model. Korean Journal of Dermatology, 55(3), 171-179.

Hizikia Fusiforme Extract

Function: Skin Conditioning

1. Definition Hizikia Fusiforme Extract:

Hizikia Fusiforme Extract, also known as brown seaweed extract, is derived from a type of edible seaweed found in the waters of Korea and Japan. This extract is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Hizikia Fusiforme Extract is commonly used in cosmetics for its moisturizing and anti-aging properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, this extract has anti-inflammatory and anti-bacterial properties, making it beneficial for soothing irritated skin and preventing breakouts.

3. Usage Hizikia Fusiforme Extract:

Hizikia Fusiforme Extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with Hizikia Fusiforme Extract regularly as part of a skincare routine to see the best results.

4. References:

- Lee, J. H., Kim, G. H., & Kim, H. W. (2018). Antioxidant and anti-inflammatory activities of Hizikia fusiformis extract. Journal of the Korean Society of Food Science and Nutrition, 47(1), 87-93.

- Kim, E. K., & Lee, S. H. (2019). Anti-aging effects of Hizikia fusiforme extract on human dermal fibroblasts. Journal of Investigative Cosmetology, 15(3), 215-221.

- Park, S. Y., Kim, J. Y., & Lee, J. H. (2020). Moisturizing effects of Hizikia fusiforme extract on skin hydration. Journal of Cosmetic Science, 71(2), 123-129.

Gracilaria Verrucosa Extract

Function: