1. Definition Alcohol:

Alcohol in cosmetics refers to the various types of alcohols that are commonly used in skincare and beauty products. These alcohols can be derived from natural sources or synthetically produced and are often included in formulations for their ability to dissolve other ingredients, act as preservatives, and provide a lightweight texture.

2. Use:

Alcohol in cosmetics is commonly used as a solvent to dissolve other ingredients in a formulation, such as essential oils, fragrances, and active ingredients. It can also act as a preservative to help extend the shelf life of a product by inhibiting the growth of bacteria and fungi. Additionally, certain types of alcohols, such as fatty alcohols, can provide emollient properties to help moisturize and soften the skin.

3. Usage Alcohol:

While alcohol can have beneficial properties in cosmetics, it is important to use products containing alcohol with caution. High concentrations of alcohol can be drying and irritating to the skin, especially for those with sensitive or dry skin. It is recommended to patch test products containing alcohol before full application and to monitor how your skin reacts to ensure it does not cause any adverse effects.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition Citrus Paradisi (Grapefruit) Fruit Extract:

Citrus Paradisi (Grapefruit) Fruit Extract is derived from the fruit of the grapefruit tree. It is known for its high content of antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Grapefruit extract is commonly used in cosmetics for its astringent and skin-brightening properties. It helps to tighten and tone the skin, reduce the appearance of pores, and improve overall skin texture. Additionally, grapefruit extract is known for its refreshing and uplifting scent, making it a popular ingredient in skincare products.

3. Usage Citrus Paradisi (Grapefruit) Fruit Extract:

Grapefruit extract can be found in a variety of skincare products, including cleansers, toners, serums, and moisturizers. It is typically used in small concentrations to avoid potential skin irritation. It is important to perform a patch test before using products containing grapefruit extract, especially for those with sensitive skin. Additionally, it is recommended to avoid using grapefruit extract on broken or irritated skin to prevent further irritation.

4. References:

- Lee, J. H., Johnson, J. V., Talcott, S. T., & Lee, S. K. (2005). Functional Citrus Paradisi (Grapefruit) Phytochemicals for Skin and Hair Care. Journal of Agricultural and Food Chemistry, 53(3), 888-892.

- Kim, S. A., & Byun, S. Y. (2010). Effects of Citrus Paradisi (Grapefruit) Peel Extract on Skin Health: A Clinical Study. International Journal of Cosmetic Science, 32(6), 463-469.

- Choi, J. H., & Kim, Y. S. (2014). Antioxidant and Anti-inflammatory Effects of Citrus Paradisi (Grapefruit) Extract in Skincare Products. Journal of Cosmetic Dermatology, 13(4), 314-321.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 60 Hydrogenated Castor Oil is primarily used in skincare and haircare products as an emulsifier to help mix oil and water-based ingredients. It also functions as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities. Additionally, it can act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil should be used in accordance with the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is important to perform a patch test before using products containing Peg 60 Hydrogenated Castor Oil to ensure compatibility with your skin.

4. References:

- CosmeticsInfo.org. (n.d.). Polyethylene glycols. https://cosmeticsinfo.org/ingredient/polyethylene-glycols

- Personal Care Council. (2019). Hydrogenated Castor Oil. https://www.personalcarecouncil.org/ingredient-info/hydrogenated-castor-oil/

- The Dermatology Review. (n.d.). Castor Oil in Skin Care: Benefits and Uses. https://thedermreview.com/castor-oil-in-skin-care/

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Sophora Angustifolia Root Extract:

Sophora Angustifolia Root Extract is a natural extract derived from the roots of the Sophora Angustifolia plant. This plant is known for its medicinal properties and has been used in traditional Chinese medicine for centuries.

2. Use:

Sophora Angustifolia Root Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-brightening properties. It is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Sophora Angustifolia Root Extract:

When using products containing Sophora Angustifolia Root Extract, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this extract.

4. References:

- Kim, S. H., Kim, H. J., Kim, Y. H., Jeong, S. J., Kim, Y. S., & Lim, D. S. (2012). Anti-inflammatory activity of compounds from the root of Sophora flavescens. Journal of ethnopharmacology, 143(3), 867-871.

- Lee, H. J., Lee, J. H., Lee, J. H., Kim, M. H., Yang, H. J., Kim, H. J., ... & Kim, J. Y. (2018). Anti-inflammatory effect of Sophora flavescens Aiton in a mouse model of phthalic anhydride-induced atopic dermatitis. Experimental and therapeutic medicine, 15(2), 1578-1584.

- Park, G. H., Song, H. M., Jeong, J. B., Hong, E. H., Chang, M., Park, J. H., ... & Lee, H. S. (2016). The root extract of Sophora flavescens enhances anti-adipogenic effect of platycodin D, a major component of Platycodon grandiflorum. Journal of ethnopharmacology, 194, 95-103.

1. Definition Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica (Honeysuckle) Flower Extract is derived from the flowers of the Japanese Honeysuckle plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Lonicera Japonica Flower Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Lonicera Japonica (Honeysuckle) Flower Extract:

Lonicera Japonica Flower Extract is typically found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine, applied to clean skin before moisturizer. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of skin, especially if you have sensitive skin.

4. References:

- Kim, J. Y., Kim, S. S., Oh, T. H., & Kim, S. K. (2006). Lonicera japonica Thunb. protects keratinocytes against hydrogen peroxide-induced apoptosis. Journal of ethnopharmacology, 104(2-3), 276-281.

- Lee, J. H., Kim, G. H., & Lee, J. S. (2015). Anti-inflammatory effect of Lonicera japonica in LPS-stimulated RAW 264.7 macrophages. Journal of Korean Medicine, 36(3), 88-97.

- Zhang, Y. J., Huang, Z. Q., & Zhang, Y. (2019). Lonicera japonica Thunb: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. Journal of ethnopharmacology, 245, 112158.

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Prunus Persica (Peach) Leaf Extract:

Prunus Persica (Peach) Leaf Extract is derived from the leaves of the peach tree and is known for its antioxidant and anti-inflammatory properties. It is commonly used in skincare products for its ability to improve skin tone, texture, and overall complexion.

2. Use:

Prunus Persica (Peach) Leaf Extract is used in cosmetics for its various benefits for the skin. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote collagen production. Additionally, it can help to brighten the skin, reduce the appearance of fine lines and wrinkles, and improve overall skin health.

3. Usage Prunus Persica (Peach) Leaf Extract:

Prunus Persica (Peach) Leaf Extract is typically found in skincare products such as serums, creams, and masks. It can be applied directly to the skin or incorporated into existing skincare routines. It is important to follow the instructions provided on the product packaging to ensure safe and effective use. As with any new skincare ingredient, it is recommended to perform a patch test before using it on larger areas of the skin to check for any potential allergic reactions.

4. References:

- Lee, M. Y., Seo, C. S., Lee, J. A., Lee, N. H., Kim, J. H., & Ha, H. (2014). Prunus persica L. Batsch Water Extract Inhibits Skin Photoaging and Induces Collagen Synthesis in Human Skin Fibroblasts. International journal of molecular sciences, 15(5), 9023–9033.

- Kim, S. Y., Kim, M. J., & Lee, N. H. (2018). Anti-inflammatory effects of Prunus persica L. Batsch flower extract in human gingival fibroblasts. Pharmacognosy magazine, 14(Suppl 1), S59–S63.

- Park, J. H., Kim, H. S., & Kim, M. J. (2019). Antioxidant and anti-inflammatory effects of Prunus persica L. Batsch flower extract in human keratinocytes. Journal of cosmetic dermatology, 18(6), 1885–1890.

1. Definition Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract is derived from the leaves of the Ginkgo Biloba tree, a plant native to China. It is known for its antioxidant properties and is commonly used in skincare products for its potential benefits in improving skin texture and reducing signs of aging.

2. Use:

Ginkgo Biloba Leaf Extract is often included in cosmetic formulations for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental stressors, such as pollution and UV radiation, and promote overall skin health. Additionally, Ginkgo Biloba Leaf Extract may help improve circulation and promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ginkgo Biloba Leaf Extract:

Ginkgo Biloba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting aging, dullness, and uneven skin tone. To incorporate Ginkgo Biloba Leaf Extract into your skincare routine, look for products specifically formulated with this ingredient and follow the instructions provided by the manufacturer.

4. References:

- Choi, H. S., Kim, M. K., Lee, K., Lee, K. M., Kim, Y. J., & Jun, W. (2017). Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells. Journal of medicinal food, 20(6), 579-586.

- Zhou, L., Gao, Q., Zhang, G., Wang, X., Zhang, J., & Zhang, L. (2018). Ginkgo biloba extract inhibits astrocytic lipocalin‐2 expression and alleviates neuroinflammatory injury via the JAK2/STAT3 pathway after ischemic brain stroke. Phytotherapy Research, 32(12), 2527-2536.

- Kaur, N., Kishore, L., Singh, R., & Singh, S. (2018). Ginkgo biloba: A potential natural product in the treatment of metabolic syndrome. Pharmacognosy reviews, 12(23), 111.

1. Definition Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract is a botanical ingredient derived from the roots of the Scutellaria Baicalensis plant, also known as Chinese skullcap. This extract is rich in flavonoids, particularly baicalin and baicalein, which are known for their antioxidant and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Root Extract is commonly used in skincare and cosmetic products for its various benefits. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting sensitive or acne-prone skin, as it can help soothe irritation and calm redness.

3. Usage Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., Evaluation of the anti-inflammatory and anti-oxidant effects of Scutellaria baicalensis root extract in human keratinocytes. Biomed Res Int. 2019; 2019: 5390806.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C., In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002; 16(5): 440-444.

- Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. A., Ruscetti, F. W., Wang, J. M., Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000; 276(2): 534-538.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Dibutyl Adipate:

Dibutyl Adipate is a clear, colorless liquid commonly used as an emollient in cosmetics. It is a diester of butyl alcohol and adipic acid, and it is known for its ability to soften and smooth the skin.

2. Use:

Dibutyl Adipate is primarily used in skincare and haircare products as a moisturizing agent. It helps to improve the texture of the skin and hair, making them feel soft and smooth. Additionally, it is often used in sunscreens and other products to enhance their spreadability and provide a non-greasy feel.

3. Usage Dibutyl Adipate:

Dibutyl Adipate is typically incorporated into cosmetic formulations at concentrations ranging from 1% to 10%. It is commonly found in creams, lotions, serums, and other emollient-rich products. When using products containing Dibutyl Adipate, it is important to follow the manufacturer's instructions and avoid applying it to broken or irritated skin.

Precautions: While Dibutyl Adipate is considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient extensively. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Dibutyl Adipate. International Journal of Toxicology. 2003; 22(Suppl 2): 1-10.

- Personal Care Products Council. Dibutyl Adipate. https://www.cosmeticsinfo.org/ingredient/dibutyl-adipate. Accessed November 15, 2021.

- U.S. Food and Drug Administration. Code of Federal Regulations Title 21. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=178.3720. Accessed November 15, 2021.

1. Definition C12 15 Alkyl Benzoate:

C12-15 Alkyl Benzoate is an ester derived from benzoic acid and a mixture of alcohols with carbon chain lengths ranging from 12 to 15. It is commonly used in cosmetics as an emollient, skin conditioning agent, and solvent.

2. Use:

C12-15 Alkyl Benzoate is utilized in various cosmetic formulations such as sunscreens, moisturizers, and makeup products. It helps to improve the spreadability of products, enhance skin feel, and provide a lightweight, non-greasy texture.

3. Usage C12 15 Alkyl Benzoate:

When using products containing C12-15 Alkyl Benzoate, it is important to follow the recommended guidelines and apply as directed on the product packaging. It is generally considered safe for topical application, but individuals with sensitive skin may want to perform a patch test before widespread use to ensure compatibility.

Precautions: While C12-15 Alkyl Benzoate is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional. It is recommended to avoid contact with eyes and mucous membranes.

4. References:

- "C12-15 Alkyl Benzoate" in the International Cosmetic Ingredient Dictionary and Handbook, 14th Edition.

- Cosmetic Ingredient Review Expert Panel. (2003). Final report on the safety assessment of C12-15 Alkyl Benzoate.

- Personal Care Products Council. (2019). CIR Expert Panel Reaffirms Safety of C12-15 Alkyl Benzoate in Cosmetics.

1. Definition Diethylamino Hydroxybenzoyl Hexyl Benzoate:

Diethylamino Hydroxybenzoyl Hexyl Benzoate, also known as DHHB, is a chemical compound commonly used in cosmetics as a broad-spectrum UV filter. It is classified as a sunscreen agent and is known for its ability to protect the skin from both UVA and UVB rays.

2. Use:

Diethylamino Hydroxybenzoyl Hexyl Benzoate is primarily used in sunscreen products to provide protection against harmful UV radiation. It is often included in formulations for its photostability and efficacy in blocking both UVA and UVB rays. DHHB is commonly found in sunscreens, day creams, and other skincare products intended for sun protection.

3. Usage Diethylamino Hydroxybenzoyl Hexyl Benzoate:

When using products containing Diethylamino Hydroxybenzoyl Hexyl Benzoate, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with DHHB generously to all exposed skin, including the face, neck, and any other areas not covered by clothing. Reapply sunscreen every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.11.003

- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747

- Food and Drug Administration (FDA). Sunscreen Drug Products for Over-the-Counter Human Use. Code of Federal Regulations Title 21, Volume 5. Revised as of April 1, 2020. Accessed June 10, 2021. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352

1. Definition Polysilicone 15:

Polysilicone 15 is a type of silicone-based ingredient commonly used in cosmetics and personal care products. It is a film-forming agent that helps to create a smooth, silky feel on the skin while also providing some level of UV protection.

2. Use:

Polysilicone 15 is primarily used in sunscreens, moisturizers, and makeup products to enhance their texture and performance. It helps to improve the spreadability of products, making them easier to apply and blend into the skin. Additionally, it provides a lightweight, non-greasy feel that is comfortable to wear throughout the day.

3. Usage Polysilicone 15:

When using products containing Polysilicone 15, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with Polysilicone 15 as directed, making sure to cover all exposed areas of skin for maximum protection. Avoid contact with the eyes and discontinue use if any irritation occurs. It is also recommended to reapply sunscreen every two hours, especially after swimming or sweating.

4. References:

- "Polysilicone-15." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysilicone-15.

- "Polysilicone-15." The Derm Review, www.thedermreview.com/polysilicone-15/.

- Kumar, Sandeep, et al. "Polysilicone-15: A New Generation UV Filter for Sunscreen Formulations." ResearchGate, www.researchgate.net/publication/273241901_Polysilicone-15_A_New_Generation_UV_Filter_for_Sunscreen_Formulations.

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Polyglyceryl 6 Stearate:

Polyglyceryl 6 Stearate is a synthetic compound that belongs to the family of polyglycerol esters. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Polyglyceryl 6 Stearate is primarily used in cosmetics as an emulsifier, helping to blend oil and water-based ingredients together to create stable and uniform formulations. It also acts as a surfactant, reducing the surface tension of liquids and allowing for better spreadability of products. Additionally, it can function as a stabilizer, helping to maintain the consistency and texture of cosmetic products.

3. Usage Polyglyceryl 6 Stearate:

Polyglyceryl 6 Stearate is considered safe for use in cosmetics when used in accordance with regulations and guidelines. However, as with any cosmetic ingredient, some individuals may experience sensitivity or allergic reactions to this compound. It is recommended to perform a patch test before using products containing Polyglyceryl 6 Stearate, especially for those with sensitive skin or known allergies. It is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- "Polyglyceryl-6 Stearate" by CosIng - European Commission

- "Polyglyceryl Stearates" by The Derm Review

- "Polyglyceryl Esters" by Cosmetics Info

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Synthetic Fluorphlogopite:

Synthetic Fluorphlogopite, also known as synthetic mica, is a mineral-derived synthetic ingredient commonly used in cosmetics as a replacement for natural mica. It is a synthetic version of fluorophlogopite, a mineral that belongs to the mica group.

2. Use:

Synthetic Fluorphlogopite is primarily used in cosmetics for its shimmering and light-reflecting properties. It is often used in eyeshadows, highlighters, and other makeup products to add a luminous and glittery effect to the skin. It can also be used in skincare products to provide a smooth and silky texture.

3. Usage Synthetic Fluorphlogopite:

When using products containing Synthetic Fluorphlogopite, it is important to be aware of any potential allergies or sensitivities to mica or other minerals. It is recommended to perform a patch test before using products with this ingredient to avoid any adverse reactions. Additionally, as with any cosmetic product, it is important to follow the manufacturer's instructions for proper application and storage to ensure the product's effectiveness and longevity.

4. References:

- "Synthetic Fluorphlogopite" by Cosmetics Info

- "What Is Synthetic Fluorphlogopite?" by The Derm Review

- "Understanding the Role of Synthetic Fluorphlogopite in Cosmetics" by Personal Care Magazine

1. Definition Methylene Bis-Benzotriazolyl Tetramethylbutylphenol:

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, also known as Tinosorb M, is a chemical compound used in sunscreens and other cosmetic products as a broad-spectrum UV filter. It is a photostable organic compound that helps protect the skin from both UVA and UVB rays.

2. Use:

Tinosorb M is primarily used in sunscreens to provide protection against the harmful effects of UV radiation. It is effective in preventing sunburn, premature skin aging, and skin cancer caused by exposure to the sun's rays. This compound is often used in combination with other UV filters to enhance the overall sun protection factor (SPF) of a product.

3. Usage Methylene Bis-Benzotriazolyl Tetramethylbutylphenol:

When using products containing Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is recommended to use sunscreen with a minimum SPF of 30 and to seek shade during peak sun hours to further protect the skin.

4. References:

- M. G. Leblanc, M. C. Gaudreault, M. S. Corbeil, J. P. H. Bouchard, and M. G. Bergeron, "Absorption of the Sunscreen Benzophenone-3 after Swimming in Chlorinated Water," Journal of Investigative Dermatology, vol. 123, no. 5, pp. 917-922, 2004.

- E. Berardesca, M. Distante, and M. Vignoli, "Efficacy of Methylene Bis-Benzotriazolyl Tetramethylbutylphenol in the Prevention of Polymorphic Light Eruption," Dermatology, vol. 207, no. 3, pp. 312-315, 2003.

- J. A. Parrish, M. A. Pathak, and L. D. Fitzpatrick, "Phototoxic and Photoallergic Reactions Associated with Sunscreens," Photodermatology, vol. 1, no. 2, pp. 79-98, 1984.

1. Definition Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, also known as Tinosorb S, is a chemical compound commonly used in sunscreen formulations as a broad-spectrum UV filter. It belongs to the class of organic compounds known as phenylbenzimidazoles.

2. Use:

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is used in cosmetic products, especially in sunscreens, to provide protection against both UVA and UVB rays. It is known for its photostability and effectiveness in preventing sunburn and skin damage caused by exposure to the sun's harmful rays.

3. Usage Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine:

When using products containing Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, it is important to follow the instructions provided on the product label. Apply the sunscreen generously to all exposed skin at least 15 minutes before going outside, and reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Moyal D. (2008). Molecular and clinical rationale for the use of a broad-spectrum sunscreen: a review of the evidence. Journal of Drugs in Dermatology, 7(2 Suppl):6-12.

- Matta M.K., et al. (2010). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: a randomized clinical trial. JAMA, 323(3):256-67.

- Nash J.F., et al. (2006). Sunscreens with photostable UVA filters prevent the generation of reactive oxygen species and cyclobutane pyrimidine dimers in human skin exposed to UVA radiation. Pigment Cell Research, 19(4):364-74.

1. Definition Ethylhexyl Triazone:

Ethylhexyl Triazone, also known as Octyl Triazone, is a chemical compound commonly used in sunscreens and other cosmetic products as a UV filter. It is a water-insoluble organic compound that absorbs UVB radiation, providing protection against sunburn and skin damage.

2. Use:

Ethylhexyl Triazone is primarily used in sunscreens to enhance their UV protection capabilities. It works by absorbing UVB rays and converting them into less harmful energy, preventing them from penetrating the skin and causing damage. This ingredient is often combined with other UV filters, such as avobenzone or octocrylene, to provide broad-spectrum protection against both UVA and UVB radiation.

3. Usage Ethylhexyl Triazone:

When using products containing Ethylhexyl Triazone, it is important to follow the instructions provided on the packaging. Apply the sunscreen generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures, such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2012.01.001

- Sarveiya V, Risk S, Benson HAE. Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;803(2):225-231. doi:10.1016/j.jchromb.2003.11.032

- Moyal D. Fourcroy P. Broad-spectrum sunscreens: importance of protection against UVA and UVB radiation. J Am Acad Dermatol. 2008;58(5 Suppl 2):S139-S148. doi:10.1016/j.jaad.2007.04.031

1. Definition Polyglyceryl 6 Behenate:

Polyglyceryl 6 Behenate is a type of emulsifier derived from a mixture of glycerin and behenic acid. It is commonly used in cosmetics and personal care products to stabilize emulsions, improve texture, and enhance the overall feel of the product.

2. Use:

Polyglyceryl 6 Behenate is primarily used as an emulsifier in cosmetic formulations. It helps to blend water and oil-based ingredients together, creating a smooth and uniform product. Additionally, it can also act as a thickening agent, helping to give products a luxurious and creamy texture.

3. Usage Polyglyceryl 6 Behenate:

When using products containing Polyglyceryl 6 Behenate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation occurs, it is best to discontinue use and consult a dermatologist.

4. References:

- Saeidnia, S. et al. (2015). Cosmetics: From Extraction to Application. Springer.

- Lodeiro, C. et al. (2017). Formulating, Packaging, and Marketing of Natural Cosmetic Products. John Wiley & Sons.

- Dweck, A. C. (2006). Formulating Natural Cosmetics. Allured Publishing Corporation.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Decyl Glucoside:

Decyl Glucoside is a mild, non-ionic surfactant derived from natural sources such as coconut oil and glucose. It is known for its gentle cleansing properties and ability to create a rich lather without stripping the skin of its natural oils.

2. Use:

Decyl Glucoside is commonly used in cosmetics and personal care products as a primary or secondary surfactant. It is often found in cleansers, shampoos, body washes, and baby products due to its mild nature and ability to effectively remove dirt and impurities from the skin and hair.

3. Usage Decyl Glucoside:

When using products containing Decyl Glucoside, it is important to follow the manufacturer's instructions for application. It is generally considered safe for all skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Decyl Glucoside." The Derm Review, www.thedermreview.com/decyl-glucoside/

- "Decyl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/decyl-glucoside

- "Decyl Glucoside." Truth in Aging, www.truthinaging.com/ingredients/decyl-glucoside

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Dioscorea Japonica Root Extract:

Dioscorea Japonica Root Extract is an extract derived from the root of the Dioscorea Japonica plant, which is a species of yam native to East Asia. This extract is known for its skin-soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Dioscorea Japonica Root Extract is commonly used in cosmetics for its ability to calm and soothe the skin. It is often included in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is believed to have antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Dioscorea Japonica Root Extract:

Dioscorea Japonica Root Extract is typically found in skincare products such as creams, serums, and masks. It can be used both in the morning and evening as part of a skincare routine. When using products containing this extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kim, S. H., Kim, M. J., Yang, W. M., & Kim, H. G. (2017). Anti-inflammatory effects of the Dioscorea nipponica extract in LPS-stimulated RAW264.7 macrophages. Preventive Nutrition and Food Science, 22(2), 144-150.

- Park, C. H., Kim, J. H., & Kim, S. Y. (2012). Protective effects of diosgenin in the activity of matrix metalloproteinase-2 in human skin fibroblasts in vitro. Archives of Dermatological Research, 304(6), 467-474.

- Lee, S. Y., Lee, J. S., Kim, Y. H., & Lee, S. Y. (2014). Protective effects of Dioscorea japonica Thunb. on UVB-induced damage in human keratinocytes. Journal of Ethnopharmacology, 152(2), 240-248.

1. Definition Laminaria Japonica Extract:

Laminaria Japonica Extract is a natural ingredient derived from the brown seaweed Laminaria Japonica, commonly known as Kombu. It is rich in vitamins, minerals, antioxidants, and amino acids, making it a popular ingredient in skincare and cosmetics.

2. Use:

Laminaria Japonica Extract is known for its hydrating, anti-inflammatory, and anti-aging properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. Additionally, it has been shown to have brightening and firming effects on the skin.

3. Usage Laminaria Japonica Extract:

Laminaria Japonica Extract is commonly found in various skincare products such as serums, creams, masks, and lotions. It can be used daily as part of a skincare routine to help nourish and protect the skin. When using products containing Laminaria Japonica Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts - A review. Food Research International, 39(4), 383-393.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Antioxidant effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 7-15.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Anti-inflammatory effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 82-88.

1. Definition Viola Mandshurica Flower Extract:

Viola Mandshurica Flower Extract is a natural ingredient derived from the flowers of the Viola Mandshurica plant, which is native to East Asia. It is known for its soothing and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Viola Mandshurica Flower Extract is commonly used in cosmetics for its anti-inflammatory and antioxidant benefits. It helps to calm and hydrate the skin, making it suitable for sensitive or irritated skin types. Additionally, it can help to improve the overall appearance of the skin by reducing redness and promoting a more even skin tone.

3. Usage Viola Mandshurica Flower Extract:

Viola Mandshurica Flower Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of the skin to ensure compatibility.

4. References:

- Kim, H. S., Kim, J. H., & Kim, J. Y. (2013). Skin protective effect of Viola mandshurica W. Becker extracts in hairless mice. Journal of the Korean Society of Food Science and Nutrition, 42(3), 407-413.

- Choi, J. H., & Kim, S. H. (2015). Anti-inflammatory and anti-oxidant effects of Viola mandshurica extracts on RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 44(9), 1324-1331.

- Lee, J. H., Kim, J. H., & Kim, J. Y. (2012). Anti-inflammatory effect of Viola mandshurica W. Becker extracts in RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 41(1), 48-54.

1. Definition Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is an extract derived from the root of the Ulmus Davidiana tree, also known as the David Elm. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Ulmus Davidiana Root Extract is commonly used in cosmetics for its various skin benefits. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, this extract can help improve skin tone and texture, resulting in a more radiant and youthful complexion.

3. Usage Ulmus Davidiana Root Extract:

Ulmus Davidiana Root Extract is typically found in skincare products such as serums, creams, and masks. It is recommended to use products containing this extract as directed by the manufacturer. As with any new skincare ingredient, it is important to perform a patch test before using it on the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Lee, Y. H., Kim, J. H., Song, M. Y., & Park, S. Y. (2015). Antioxidant and anti-inflammatory activities of the ethanolic extract of Ulmus davidiana var. japonica. Journal of Life Science, 25(2), 177-183.

- Kim, J. Y., Kim, H. J., Kim, O. Y., & Lee, J. H. (2016). Anti-inflammatory effects of Ulmus davidiana var. japonica in RAW 264.7 cells. Journal of Life Science, 26(8), 904-911.

- Park, S. Y., Lee, Y. H., Kim, J. H., & Song, M. Y. (2017). Skin-brightening effects of Ulmus davidiana var. japonica extract in human skin cells. Journal of Cosmetic Science, 68(3), 185-192.