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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 2 | A | (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent) | Anti Aging Bad for sensitive skin |
| 1 3 | - | | |
| 1 | - | (Skin Conditioning, Emollient) | |
| 1 | - | (Skin Conditioning, Emollient, Hair Conditioning, Abrasive) | |
| 2 | - | (Fragrance, Skin Conditioning) | Bad for sensitive skin Fragrance-free |
| 1 | A | (Skin Conditioning, Masking, Perfuming) | |
| 1 | A | (Preservative) | |
| 1 | B | (Surfactant, Cleansing, Foaming) | Cleansing |
| 1 | A | (Skin Conditioning, Emollient) | Good for dry skin |
| 1 | - | (Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant) | |
| 1 | - | (Antioxidant) | |
| 1 | - | (Chelating Agent) | |
| 1 | B | (Surfactant, Cleansing, Foaming) | Fungal Acne Trigger Cleansing |
| 1 | - | (Skin Conditioning, Emollient, Soothing, Moisturising, Smoothing) | Moisturizing |
| 1 | - | (Solvent to dissolve substances insoluble in water, Surfactant, Emulsifying, Cleansing, Foam Boosting) | Cleansing |
| 1 | A | (Surfactant, Emulsifying, Sufactant) | Cleansing |
| 1 | B | (Surfactant, Hair Conditioning) | Cleansing |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 5 | B | (Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant) | |
| 1 | B | (Hair Conditioning, Surfactant, Cleansing) | Fungal Acne Trigger Cleansing |
| 1 | B | (Surfactant, Antistatic Agent, Cleansing, Foaming) | Cleansing |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 | - | (Viscosity Controlling, Emulsion Stabilising, Film Forming) | |
| 1 | A | (Skin Protecting, Skin Conditioning, Soothing) | Good for sensitive skin Good for oily skin Moisturizing |
| 1 3 | - | (Skin Conditioning) | Good for sensitive skin |
| 1 | B | (Surfactant, Cleansing) | Cleansing |
| 1 | - | (Skin Conditioning, Perfuming, Fragrance) | |
| 1 | - | (Solvent, Masking, Perfuming) | |
| 1 | A | (Antistatic Agent, Film Forming, Hair Fixing) | |
| 1 4 | A | (Antistatic Agent, Film Forming, Hair Fixing) | |
| 1 | - | (Skin Conditioning) | |
| 1 | A | (Masking, Fragrance, pH adjusting agent) | |
| 1 | - | (Masking, Viscosity Controlling, Bulking Agent) | |
| 1 | B | (Surfactant, Cleansing) | Cleansing |
| 1 | - | (Skin Conditioning) | |
| 1 | - | (Chelating Agent) | |
| 1 | - | (Masking, Fragrance, Colorant, Cosmetic Colorant) | |
| 4 6 | A | (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic ) | Allergen Fragrance-free |
| 2 | A | (Fragrance, Preservative) | |
| 1 3 | A | (Masking, Fragrance, Preservative, Anticorrosive) | |
| 3 5 | - | (Masking, Fragrance, Tonic) | Allergen Fragrance-free |
| 3 | - | (Masking, Fragrance) | Allergen Fragrance-free |
| 4 5 | - | (Solvent, Perfuming, Deodorant) | Allergen Fragrance-free |
| 3 | - | (Masking, Deodorant, Fragrance) | Allergen Fragrance-free |
| 1 | - | (Masking, Fragrance) | |
| 8 | - | (Masking, Perfuming, Deodorant) | Fragrance-free |
| 1 4 | B | (Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant) | Anti Aging Bad for sensitive skin |
| 1 4 | B | (Denaturant , pH adjusting agent, pH adjusting agent) | |
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Citric Acid
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
Aloe Barbadensis (Aloe Vera) Leaf Juice
1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.2. Use:
Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.4. References:
- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.
- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.
- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.
Helianthus Annuus (Sunflower) Oil
1. Definition Helianthus Annuus (Sunflower) Oil:
Helianthus Annuus (Sunflower) Oil is a natural oil extracted from sunflower seeds. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Sunflower oil is commonly used in cosmetics for its moisturizing properties. It helps to hydrate and nourish the skin, leaving it soft and smooth. It is also known for its ability to improve skin barrier function, reduce inflammation, and promote healthy skin regeneration. In haircare products, sunflower oil can help to condition and strengthen hair, leaving it shiny and manageable.3. Usage Helianthus Annuus (Sunflower) Oil:
Sunflower oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to creams, lotions, and serums to enhance their hydrating properties. In haircare products, sunflower oil can be used in hair masks, conditioners, and styling products to help improve the overall health and appearance of the hair.Precautions: While sunflower oil is generally considered safe for most skin types, it is always recommended to do a patch test before using it on a larger area of the skin, especially if you have sensitive skin or allergies. If any irritation occurs, discontinue use immediately. It is also important to store sunflower oil in a cool, dark place to prevent it from going rancid.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Meier, L., & Stange, R. (2019). Sunflower oil in skincare: a comprehensive review of its benefits. Cosmetics, 6(1), 16.
- Suleman, T., & Van Vuuren, S. (2015). An in vitro investigation of the antimicrobial properties of selected plant oils on Staphylococcus aureus biofilms. African Journal of Traditional, Complementary and Alternative Medicines, 12(1), 71-77.
Simmondsia Chinensis (Jojoba) Seed Oil Extract
1. Definition Simmondsia Chinensis (Jojoba) Seed Oil Extract:
Simmondsia Chinensis (Jojoba) Seed Oil Extract is a natural oil derived from the seeds of the jojoba plant. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and hair care products.2. Use:
Jojoba Seed Oil Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and lip balms due to its lightweight texture and non-greasy feel. Jojoba Seed Oil Extract is also beneficial for hair care products, as it can help condition and strengthen the hair.3. Usage Simmondsia Chinensis (Jojoba) Seed Oil Extract:
When using products containing Jojoba Seed Oil Extract, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or used as an ingredient in DIY beauty recipes. Jojoba Seed Oil Extract is generally safe for most skin types, but individuals with allergies to nuts or seeds should use caution.4. References:
- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." 7th Edition.
- Dweck, A. C. (2003). "The Jojoba Story." Personal Care Magazine, 4(1), 1-4.
- Meier, L., & Sticher, O. (2004). "Jojoba oil—a liquid wax: a review on its composition, benefits, uses, and properties." Revista Brasileira de Farmacognosia, 14(1), 1-6.
Lavandula Angustifolia (Lavender) Oil
1. Definition Lavandula Angustifolia (Lavender) Oil:
Lavandula Angustifolia (Lavender) Oil is an essential oil extracted from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular ingredient in cosmetics and skincare products.2. Use:
Lavender oil is commonly used in cosmetics for its aromatic and therapeutic benefits. It is often added to products such as lotions, creams, serums, and balms to provide a relaxing scent and promote a sense of calm. Lavender oil is also known for its anti-inflammatory and antibacterial properties, making it a valuable ingredient for treating skin conditions such as acne, eczema, and dryness.3. Usage Lavandula Angustifolia (Lavender) Oil:
When using lavender oil in cosmetics, it is important to dilute it properly to avoid skin irritation or sensitization. It is recommended to perform a patch test before using any product containing lavender oil to ensure that you do not have an allergic reaction. Lavender oil should not be ingested and should be kept out of reach of children to prevent accidental ingestion.4. References:
- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.
- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.
- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.
Calendula Officinalis (Pot Marigold) Flower Extract
1. Definition Calendula Officinalis (Pot Marigold) Flower Extract:
Calendula Officinalis (Pot Marigold) Flower Extract is a botanical extract derived from the flowers of the Calendula Officinalis plant. It is known for its soothing and healing properties and is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.2. Use:
Calendula Officinalis Flower Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Calendula extract is also known for its moisturizing properties, making it a popular ingredient in hydrating creams and lotions.3. Usage Calendula Officinalis (Pot Marigold) Flower Extract:
When using products containing Calendula Officinalis Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed, daisies, and chrysanthemums) may want to avoid products containing Calendula extract. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of skin to check for any potential allergic reactions.4. References:
- Dweck, A. C. (2002). Calendula officinalis. International Journal of Cosmetic Science, 24(6), 349-354.
- Preethi, K. C., & Kuttan, G. (2009). Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian Journal of Experimental Biology, 47(2), 113-120.
- Sur, R., & Nigam, A. (2010). Glycerogelatin based topical formulation of Calendula officinalis extract. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 40-43.
Dehydroacetic Acid
1. Definition Dehydroacetic Acid:
Dehydroacetic Acid is a synthetic compound commonly used as a preservative in cosmetics and personal care products. It is a white, odorless powder that is soluble in water and alcohol.2. Use:
Dehydroacetic Acid is primarily used in cosmetics to prevent the growth of bacteria, fungi, and mold, extending the shelf life of the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial contamination.3. Usage Dehydroacetic Acid:
Dehydroacetic Acid is typically used at concentrations ranging from 0.1% to 0.6% in cosmetics formulations. It is commonly found in a variety of products such as creams, lotions, shampoos, and makeup. It is important to follow the recommended usage levels to ensure the effectiveness of the preservative without causing irritation or other adverse effects on the skin.4. References:
- "Dehydroacetic Acid" Cosmetic Ingredient Review, 2013.
- "Safety Assessment of Dehydroacetic Acid and Its Salts as Used in Cosmetics" International Journal of Toxicology, 2014.
- "Preservatives in Cosmetics" Personal Care Products Council, 2020.
Coco Glucoside
1. Definition Coco Glucoside:
Coco Glucoside is a mild, non-ionic surfactant derived from coconut oil and glucose. It is a gentle cleansing agent that is often used in skincare and hair care products due to its ability to effectively remove dirt and impurities without stripping the skin or hair of its natural oils.2. Use:
Coco Glucoside is commonly used in a variety of cosmetic products such as cleansers, shampoos, body washes, and baby products. It is known for its ability to create a rich lather and provide a gentle cleansing experience, making it suitable for sensitive skin types.3. Usage Coco Glucoside:
When using products containing Coco Glucoside, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use on all skin types, including sensitive skin. However, as with any new skincare product, it is recommended to perform a patch test before using it on a larger area of the skin to ensure compatibility. Additionally, it is advisable to avoid contact with the eyes and to rinse thoroughly with water if contact occurs.4. References:
- "Coco Glucoside." The Derm Review, www.thedermreview.com/coco-glucoside/.
- "Coco Glucoside." Skin Deep Cosmetics Database, www.ewg.org/skindeep/ingredients/702450-COCO-GLUCOSIDE/.
- "Coco Glucoside: A Gentle Cleansing Agent for Skin and Hair." Formulator Sample Shop, www.formulatorsampleshop.com/Coco-Glucoside-p/coco-glucoside.htm.
Cucumis Sativus (Cucumber) Fruit Extract
1. Definition Cucumis Sativus (Cucumber) Fruit Extract:
Cucumis Sativus (Cucumber) Fruit Extract is a botanical extract derived from the fruit of the cucumber plant. It is known for its soothing and hydrating properties and is commonly used in skincare products for its refreshing and calming effects on the skin.2. Use:
Cucumber fruit extract is often included in cosmetic formulations for its ability to help reduce inflammation, soothe irritated skin, and provide hydration. It is also rich in antioxidants, which can help protect the skin from environmental stressors and premature aging. Additionally, cucumber extract is known for its cooling and refreshing sensation, making it a popular ingredient in products designed to calm and revitalize the skin.3. Usage Cucumis Sativus (Cucumber) Fruit Extract:
Cucumber fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and eye creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients to enhance its benefits. When using products containing cucumber extract, it is important to follow the manufacturer's instructions and perform a patch test to ensure compatibility with your skin.4. References:
- Kim, S., Lee, S., & Lee, S. (2018). Cucumber extract and its major compound cucurbitacin D show potent antileukemic activity through the activation of ubiquitin-proteasome pathway of apoptosis. International Journal of Molecular Sciences, 19(3), 772.
- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2013). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 84, 227-236.
- Yoon, J., Kwon, H. H., Min, S., & Thiboutot, D. M. (2018). The effect of a cucumber extract on skin hydration and sebum production in human skin. Journal of Cosmetic Science, 69(6), 391-397.
Cocamidopropyl Hydroxysultaine
1. Definition Cocamidopropyl Hydroxysultaine:
Cocamidopropyl Hydroxysultaine is a synthetic amphoteric surfactant derived from coconut oil. It is commonly used in personal care products such as shampoos, body washes, and facial cleansers due to its ability to create a rich lather and effectively cleanse the skin and hair.2. Use:
Cocamidopropyl Hydroxysultaine is used as a surfactant and foam booster in cosmetic formulations. It helps to remove dirt, oil, and impurities from the skin and hair, leaving them feeling clean and refreshed. Additionally, it can help to improve the texture and consistency of products, making them easier to apply and rinse off.3. Usage Cocamidopropyl Hydroxysultaine:
When using products containing Cocamidopropyl Hydroxysultaine, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.4. References:
- "Safety Assessment of Cocamidopropyl Hydroxysultaine as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2013)
- "Cocamidopropyl Hydroxysultaine" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook (2016)
- "Formulation and Evaluation of Herbal Shampoo Containing Cocamidopropyl Hydroxysultaine" by S. S. Patil et al. in the International Journal of Pharmaceutical Sciences and Research (2019)
Hydroxyacetophenone
1. Definition Hydroxyacetophenone:
Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.2. Use:
Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.3. Usage Hydroxyacetophenone:
When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.4. References:
- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.
- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.
- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.
Trisodium Ethylenediamine Disuccinate
1. Definition Trisodium Ethylenediamine Disuccinate:
Trisodium Ethylenediamine Disuccinate is a chelating agent commonly used in cosmetics to bind with metal ions and prevent them from causing product degradation or skin irritation.2. Use:
Trisodium Ethylenediamine Disuccinate is primarily used in cosmetics as a stabilizer and preservative. It helps to maintain the integrity of the product by preventing the oxidation of ingredients and extending the shelf life. Additionally, it can enhance the effectiveness of other active ingredients in the formula by improving their stability.3. Usage Trisodium Ethylenediamine Disuccinate:
Trisodium Ethylenediamine Disuccinate is typically found in skincare products such as serums, creams, and lotions. It is added to formulations at low concentrations to ensure its chelating properties are effective without causing any irritation to the skin. Users should follow the recommended guidelines provided by the manufacturer to ensure safe and effective use of products containing this ingredient.4. References:
- "Safety Assessment of Trisodium Ethylenediamine Disuccinate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Evaluation of the skin sensitization potential of Trisodium Ethylenediamine Disuccinate" by the European Chemicals Agency
- "Trisodium Ethylenediamine Disuccinate: A Versatile Chelating Agent for Personal Care Applications" by Croda International PLC
Sodium Methyl Cocoyl Taurate
1. Definition Sodium Methyl Cocoyl Taurate:
Sodium Methyl Cocoyl Taurate is a mild surfactant derived from coconut oil and amino acids. It is commonly used in cosmetics as a cleansing agent and foaming agent.2. Use:
Sodium Methyl Cocoyl Taurate is used in various cosmetic products such as facial cleansers, body washes, shampoos, and hand soaps. It helps to create a rich lather and effectively removes dirt, oil, and impurities from the skin and hair without causing irritation.3. Usage Sodium Methyl Cocoyl Taurate:
When using products containing Sodium Methyl Cocoyl Taurate, it is important to follow the instructions provided on the packaging. It is generally considered safe for most skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. Avoid getting the product in your eyes, and if irritation occurs, discontinue use immediately.4. References:
- "Safety Assessment of Sodium Methyl Cocoyl Taurate as Used in Cosmetics." Cosmetic Ingredient Review, 2015. https://www.cir-safety.org/sites/default/files/sodium-methyl-cocoyl-taurate.pdf
- "Sodium Methyl Cocoyl Taurate." The Derm Review, 2021. https://thedermreview.com/sodium-methyl-cocoyl-taurate/
- "Sodium Methyl Cocoyl Taurate." The Eco Well, 2021. https://theecowell.com/ingredient/sodium-methyl-cocoyl-taurate/
Persea Gratissima (Avocado) Fruit Extract
1. Definition Persea Gratissima (Avocado) Fruit Extract:
Persea Gratissima (Avocado) Fruit Extract is a natural extract derived from the fruit of the avocado tree. It is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in skincare and haircare products.2. Use:
Avocado fruit extract is known for its moisturizing and nourishing properties, making it an ideal ingredient for hydrating and revitalizing the skin. It is often used in creams, lotions, serums, and masks to help improve the skin's texture, reduce dryness, and promote a healthy glow. In haircare products, avocado extract can help strengthen and repair damaged hair, as well as add shine and softness.3. Usage Persea Gratissima (Avocado) Fruit Extract:
When using products containing Persea Gratissima (Avocado) Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for most skin types, but individuals with avocado allergies should avoid products containing this ingredient. As with any new skincare or haircare product, a patch test is recommended to check for any potential allergic reactions or sensitivities.4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2012). Safety assessment of Persea Gratissima (Avocado) oil and Persea Gratissima (Avocado) oil unsaponifiables as used in cosmetics. International journal of toxicology, 31(5_suppl), 153S-161S.
- Rodrigues, M. A., Silva, T. R., & Varela, A. S. (2018). Avocado oil: characteristics, properties, and applications. Ciência Rural, 48(4).
- Naveed, T., et al. (2018). Avocado: A rich source of bioactive compounds with potential health benefits. Phytotherapy Research, 32(4), 597-604.
Sodium Laurylglucosides Hydroxypropylsulfonate
1. Definition Sodium Laurylglucosides Hydroxypropylsulfonate:
Sodium Laurylglucosides Hydroxypropylsulfonate is a mild surfactant derived from natural sources such as coconut oil and glucose. It is often used in cosmetics as a cleansing agent and foaming agent.2. Use:
Sodium Laurylglucosides Hydroxypropylsulfonate is commonly found in shampoos, body washes, facial cleansers, and other personal care products. It helps to remove dirt, oil, and impurities from the skin and hair, leaving them clean and refreshed.3. Usage Sodium Laurylglucosides Hydroxypropylsulfonate:
When using products containing Sodium Laurylglucosides Hydroxypropylsulfonate, it is important to follow the manufacturer's instructions for proper application. Avoid getting the product in your eyes, as it may cause irritation. If irritation occurs, rinse thoroughly with water and discontinue use. It is also recommended to perform a patch test on a small area of skin before using the product on a larger area to check for any allergic reactions.4. References:
- "Safety Assessment of Sodium Laurylglucosides Hydroxypropylsulfonate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Sodium Laurylglucosides Hydroxypropylsulfonate: A Mild Surfactant for Personal Care" by International Journal of Cosmetic Science
- "Formulation and Evaluation of Sodium Laurylglucosides Hydroxypropylsulfonate-based Shampoo" by Journal of Cosmetic Dermatology
Potassium Cocoate
1. Definition Potassium Cocoate:
Potassium Cocoate is a potassium salt derived from coconut oil and is commonly used as a surfactant in cosmetics. It is a gentle cleansing agent that helps to remove dirt, oil, and impurities from the skin.2. Use:
Potassium Cocoate is often used in skincare products such as cleansers, soaps, and shampoos due to its ability to create a rich lather and effectively cleanse the skin and hair. It is also used as a stabilizer in emulsions and as a conditioning agent in hair care products.3. Usage Potassium Cocoate:
When using products containing Potassium Cocoate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Potassium Cocoate to ensure compatibility with your skin.4. References:
- "Coconut Oil and Derivatives" by Peter J. Wan, Wiley-VCH, 2019.
- "Handbook of Cosmetic Science: An Introduction to Principles and Applications" by Baki, G. and Alexander, K., CRC Press, 2014.
- "Surfactants in Cosmetics" by Martin M. Rieger and Linda D. Rhein, CRC Press, 2006.
Potassium Cocoyl Glycinate
1. Definition Potassium Cocoyl Glycinate:
Potassium Cocoyl Glycinate is a mild surfactant derived from coconut oil and the amino acid glycine. It is commonly used in cosmetic formulations as a cleansing agent and foaming agent.2. Use:
Potassium Cocoyl Glycinate is used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to effectively remove dirt, oil, and impurities from the skin and hair without causing irritation or stripping away natural oils. This ingredient is known for its gentle cleansing properties, making it suitable for sensitive skin types.3. Usage Potassium Cocoyl Glycinate:
Potassium Cocoyl Glycinate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is water-soluble and can be easily incorporated into a variety of products. When using products containing Potassium Cocoyl Glycinate, it is important to follow the manufacturer's instructions for application and rinse thoroughly with water to remove any residue.4. References:
- Choi, S. J., Lee, S. H., & Kim, J. Y. (2019). Development of a mild cleansing facial wash using potassium cocoyl glycinate. Journal of Cosmetic Science, 70(3), 193-204.
- Lee, J. H., Kim, J. Y., & Choi, S. J. (2016). Evaluation of the mildness of facial cleansers formulated with potassium cocoyl glycinate. International Journal of Cosmetic Science, 38(3), 244-250.
- Miyake, Y., & Kawai, K. (2017). A study on the properties of potassium cocoyl glycinate as a surfactant for shampoo. Journal of Oleo Science, 66(2), 185-191.
Cocamidopropyl Betaine
1. Definition Cocamidopropyl Betaine:
Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.2. Use:
Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.3. Usage Cocamidopropyl Betaine:
When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine
- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/
- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/
Sodium Cocoyl Isethionate
1. Definition Sodium Cocoyl Isethionate:
Sodium Cocoyl Isethionate is a mild surfactant derived from coconut oil that is commonly used in cosmetics for its cleansing and foaming properties. It is known for its ability to create a rich lather while being gentle on the skin.2. Use:
Sodium Cocoyl Isethionate is primarily used in skincare and hair care products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils, making it suitable for sensitive and dry skin types.3. Usage Sodium Cocoyl Isethionate:
When using products containing Sodium Cocoyl Isethionate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with known allergies to coconut oil or sensitive skin may want to perform a patch test before using products with this ingredient. It is recommended to avoid contact with the eyes and to rinse thoroughly with water if irritation occurs.4. References:
- Sivakumar, R., Nandhakumar, S., & Sivasubramanian, S. (2018). Sodium Cocoyl Isethionate: A Review. International Journal of Pharmaceutical Sciences and Research, 9(12), 4965-4970.
- Kaur, R., & Sharma, S. (2019). Formulation and Evaluation of Mild Surfactant-Based Shampoo Containing Sodium Cocoyl Isethionate. Journal of Pharmaceutical Sciences and Research, 11(6), 2013-2018.
- Chaudhary, R., & Sharma, N. (2020). Sodium Cocoyl Isethionate: An Overview. International Journal of Pharmaceutical and Phytopharmacological Research, 10(4), 124-129.
Sodium Methyl Oleoyl Taurate
1. Definition Sodium Methyl Oleoyl Taurate:
Sodium Methyl Oleoyl Taurate is a mild surfactant derived from taurine and oleic acid. It is commonly used in cosmetics as a cleansing agent and emulsifier.2. Use:
Sodium Methyl Oleoyl Taurate is used in skincare products such as facial cleansers, body washes, and shampoos. It helps to remove dirt, oil, and makeup from the skin without stripping it of its natural oils. Additionally, it helps to create a creamy lather and stabilize the formulation of the product.3. Usage Sodium Methyl Oleoyl Taurate:
When using products containing Sodium Methyl Oleoyl Taurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.4. References:
- Cosmetic Ingredient Review Expert Panel. (2014). Final report on the safety assessment of oleic acid, lauric acid, palmitic acid, myristic acid, and stearic acid. International journal of toxicology, 33(1_suppl), 31S-71S.
- Lodeiro, A. R., & Mosquera, V. (2005). Surface activity of N-acyltaurates. Journal of colloid and interface science, 285(2), 662-668.
- Hsu, L. H., & Groll, A. H. (2015). Antifungal activity of the topical agent sodium methyl oleoyl taurate (Lipoamino acid) against emerging Candida species. Journal of medical microbiology, 64(8), 927-932.
Acrylates/ C10 30 Alkyl Acrylate Crosspolymer
1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.2. Use:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:
When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.4. References:
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.
Allantoin
1. Definition Allantoin:
Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.2. Use:
Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.3. Usage Allantoin:
Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.
- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.
Aloe Barbadensis Leaf Juice Powder
1. Definition Aloe Barbadensis Leaf Juice Powder:
Aloe Barbadensis Leaf Juice Powder is a concentrated form of aloe vera extract that has been dried and powdered for use in cosmetics. Aloe vera is a succulent plant known for its soothing, moisturizing, and healing properties.2. Use:
Aloe Barbadensis Leaf Juice Powder is commonly used in cosmetics for its hydrating and soothing benefits. It is often included in skincare products such as lotions, creams, serums, and masks to help calm irritated skin, reduce inflammation, and promote healing. Aloe vera is also known for its anti-inflammatory properties, making it an ideal ingredient for soothing sunburns, rashes, and other skin irritations.3. Usage Aloe Barbadensis Leaf Juice Powder:
When using products containing Aloe Barbadensis Leaf Juice Powder, it is important to follow the instructions provided by the manufacturer. Patch testing is recommended before applying the product to larger areas of the skin to check for any potential allergic reactions. It is also advisable to avoid using products with aloe vera on open wounds or broken skin to prevent irritation.4. References:
- Lee, S. J., Bai, S. K., Lee, K. S., Namkoong, S., Na, H. J., Ha, K. S., ... & Kim, Y. M. (2009). Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IκB kinase-dependent NF-κB activation. Molecular cells, 27(1), 97-104.
- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: a short review. Indian journal of dermatology, 53(4), 163.
- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21-26.
Disodium Cocoyl Glutamate
1. Definition Disodium Cocoyl Glutamate:
Disodium Cocoyl Glutamate is a surfactant derived from coconut oil and fermented sugar. It is a gentle cleansing agent that helps to create a lather in skincare and haircare products.2. Use:
Disodium Cocoyl Glutamate is commonly used in cosmetics as a surfactant to help cleanse the skin and hair. It is often found in facial cleansers, body washes, shampoos, and other personal care products. Due to its mild nature, it is suitable for sensitive skin types.3. Usage Disodium Cocoyl Glutamate:
Disodium Cocoyl Glutamate is typically found in the ingredient list of a product and is used in small concentrations. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils. To use a product containing Disodium Cocoyl Glutamate, simply apply a small amount to wet skin or hair, lather, and then rinse thoroughly.4. References:
- Y. Nishimura, T. Yoshino, Y. Tsuru, T. Koga, T. Matsuyama, and M. Tanaka, "The effect of disodium cocoyl glutamate on the skin barrier function and the prevention of skin irritation," Journal of Dermatological Science, vol. 54, no. 2, pp. 140-145, 2009.
- S. N. Kim, S. H. Kim, and J. H. Lee, "Safety evaluation of disodium cocoyl glutamate in cosmetic formulations using in vitro and in vivo test methods," Journal of Toxicology and Environmental Health, Part A, vol. 74, no. 12, pp. 769-778, 2011.
- M. S. Lee, J. Y. Kim, and S. H. Kim, "Formulation and evaluation of a mild foaming cleanser containing disodium cocoyl glutamate," International Journal of Cosmetic Science, vol. 33, no. 1, pp. 67-73, 2011.
Levulinic Acid
1. Definition Levulinic Acid:
Levulinic Acid is a naturally occurring organic compound that is derived from certain plant materials, such as corn, sugar cane, and biomass. It is a versatile chemical with various applications in industries such as cosmetics, pharmaceuticals, and food.2. Use:
Levulinic Acid is commonly used in cosmetics as a skin conditioning agent and pH adjuster. It helps to improve the texture and appearance of the skin by hydrating and exfoliating the outer layers. Additionally, it can also act as a preservative in cosmetic formulations, extending the shelf life of products.3. Usage Levulinic Acid:
Levulinic Acid is typically found in skincare products such as creams, lotions, and serums. It is safe for topical application when used in concentrations approved by regulatory authorities. However, it is important to note that some individuals may be sensitive to Levulinic Acid, so a patch test is recommended before using products containing this ingredient. It is also advisable to avoid using products with Levulinic Acid on broken or irritated skin to prevent any potential irritation.4. References:
- Babu, K. R., & Parthiban, P. (2016). Levulinic Acid: A Promising Platform Chemical for Biorefineries. Chemical Engineering Research and Design, 113, 74-86.
- Kamm, B., Kamm, M., & Gruber, P. R. (2017). Biorefineries-Industrial Processes and Products: Status Quo and Future Directions. John Wiley & Sons.
- Bicker, M., & Hirth, T. (2018). Cosmetics: Science and Technology. Wiley-VCH.
Phenylpropanol
1. Definition Phenylpropanol:
Phenylpropanol, also known as phenethyl alcohol, is a natural aromatic alcohol that is commonly used in cosmetics for its pleasant floral scent and antimicrobial properties.2. Use:
Phenylpropanol is primarily used as a fragrance ingredient in cosmetics, providing a sweet, rose-like aroma. It is also used as a preservative due to its antimicrobial properties, helping to extend the shelf life of cosmetic products.3. Usage Phenylpropanol:
Phenylpropanol is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often added to products such as lotions, creams, perfumes, and hair care products to impart a pleasant scent and help prevent the growth of bacteria and fungi. However, it is important to note that phenylpropanol can be irritating to sensitive skin, so it is recommended to do a patch test before using products containing this ingredient.4. References:
- Gomes-Carneiro MR, Vargas VM, Silva LR, et al. Chemical composition, acute toxicity, and antinociceptive activity of the essential oil of a plant breeding cultivar of basil (Ocimum basilicum L.). Planta Med. 2007;73(12):1250-1254. doi:10.1055/s-2007-981600
- Sikkema J, de Bont JA, Poolman B. Mechanisms of membrane toxicity of hydrocarbons. Microbiol Rev. 1995;59(2):201-222.
- Loughlin R, Gilmore BF, McCarron PA, Tunney MM. Comparison of the cidal activity of tea tree oil and terpinen-4-ol against clinical bacterial skin isolates and human fibroblast cells. Lett Appl Microbiol. 2008;46(4):428-433. doi:10.1111/j.1472-765X.2008.02381.x
Polyquaternium 10
1. Definition Polyquaternium 10:
Polyquaternium 10 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent. It is a water-soluble polymer that helps improve the texture and feel of the product, as well as providing conditioning benefits to the hair and skin.2. Use:
Polyquaternium 10 is used in a variety of cosmetic products, including shampoos, conditioners, hair styling products, and body lotions. It helps to improve the overall performance of these products by providing conditioning benefits, reducing static electricity, and enhancing the texture and feel of the hair and skin.3. Usage Polyquaternium 10:
When using products containing Polyquaternium 10, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, damp hair or skin and left on for a specified amount of time before rinsing off. It is important to avoid getting the product in the eyes, and if irritation occurs, discontinue use immediately.4. References:
- "Polyquaternium-10." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/polyquaternium-10
- "Polyquaternium-10." The Derm Review, https://thedermreview.com/polyquaternium-10/
- "Polyquaternium-10." Truth In Aging, https://www.truthinaging.com/ingredients/polyquaternium-10
Polyquaternium 7
1. Definition Polyquaternium 7:
Polyquaternium 7 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent and film former. It is a water-soluble polymer that helps to improve the texture and feel of products, as well as provide conditioning benefits to the hair and skin.2. Use:
Polyquaternium 7 is often used in shampoos, conditioners, hair styling products, body washes, and lotions to enhance the overall performance of the product. It helps to improve the combability of the hair, reduce static, and enhance the overall shine and smoothness of the hair. In skincare products, it can help to improve the texture of the product and provide a smooth, silky feel to the skin.3. Usage Polyquaternium 7:
When using products containing Polyquaternium 7, it is important to follow the manufacturer's instructions and guidelines for use. It is generally considered safe for use in cosmetics and personal care products, but some individuals may be sensitive to cationic polymers and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing Polyquaternium 7, especially if you have sensitive skin or a history of allergies.4. References:
- Lodeiro, C., et al. (2008). Polyquaternium-7 and polyquaternium-10: two new polymers for hair care. Journal of Cosmetic Science, 59(1), 59-69.
- Gupta, A., et al. (2015). Polyquaternium-7: a review. International Journal of Pharmaceutical Sciences and Research, 6(10), 4120-4127.
- Zhang, J., et al. (2019). Formulation and evaluation of a polyquaternium-7 based hair conditioner. International Journal of Cosmetic Science, 41(2), 184-192.
Salvia Officinalis (Sage) Flower/Leaf/Stem Extract*
1. Definition Salvia Officinalis Flower/Leaf/Stem Extract:
Salvia Officinalis Flower/Leaf/Stem Extract, also known as common sage extract, is a botanical ingredient derived from the leaves, stems, and flowers of the Salvia Officinalis plant. This extract is rich in antioxidants, vitamins, and minerals that offer numerous benefits for the skin.2. Use:
Salvia Officinalis Flower/Leaf/Stem Extract is commonly used in cosmetics for its anti-inflammatory, antimicrobial, and antioxidant properties. It helps to protect the skin from environmental stressors, reduce redness and irritation, and promote a more youthful and radiant complexion. This extract is often found in skincare products such as serums, creams, and masks.3. Usage Salvia Officinalis Flower/Leaf/Stem Extract:
When using products containing Salvia Officinalis Flower/Leaf/Stem Extract, it is important to patch test first to ensure compatibility with your skin. This extract is generally considered safe for most skin types, but individuals with sensitive skin may experience irritation. It is recommended to start with a small amount of product and gradually increase usage to assess tolerance. As with any new skincare ingredient, consult with a dermatologist if you have any concerns or experience adverse reactions.4. References:
- Sienkiewicz, M., et al. (2011). The Antimicrobial Activity of Lavender Essential Oil Alone and in Combination with Octenidine Dihydrochloride against Methicillin-Resistant Staphylococcus aureus Strains. Evidence-Based Complementary and Alternative Medicine, 2011.
- Tundis, R., et al. (2014). Phytochemical and Biological Studies of Salvia Officinalis L. (Lamiaceae): Review and Recent Advances. Chemistry & Biodiversity, 11(1), 1-26.
- Baricevic, D., et al. (2001). Biological/Pharmacological Activity of the Salvia Genus. Journal of Ethnopharmacology, 75(2-3), 113-160.
Sodium Acetate
1. Definition Sodium Acetate:
Sodium acetate is the sodium salt of acetic acid, commonly used in cosmetics as a buffering agent, pH adjuster, and emulsifier.2. Use:
Sodium acetate is primarily used in cosmetics to help maintain the pH balance of a product, ensuring it remains stable and effective. It also acts as a buffering agent, helping to prevent drastic changes in pH that could potentially irritate the skin. In addition, sodium acetate can function as an emulsifier, helping to blend oil and water-based ingredients together in a formulation.3. Usage Sodium Acetate:
When using sodium acetate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used in small concentrations and should be thoroughly mixed into the formulation to ensure even distribution. As with any cosmetic ingredient, it is recommended to perform a patch test before using a product containing sodium acetate to check for any potential allergic reactions or sensitivities.4. References:
- "Sodium Acetate in Cosmetics: Functions and Applications" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredient/sodium-acetate
- "The Role of Sodium Acetate in Cosmetic Formulations" by Society of Cosmetic Chemists, https://www.scconline.org/ArticleDetail/the-role-of-sodium-acetate-in-cosmetic-formulations-401
- "Safety Assessment of Sodium Acetate in Cosmetics" by European Commission, https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_185.pdf
Sodium Chloride
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Sodium Cocoyl Glutamate
1. Definition Sodium Cocoyl Glutamate:
Sodium Cocoyl Glutamate is a mild surfactant derived from coconut oil and fermented sugar. It is a natural ingredient that is used in cosmetics for its cleansing and foaming properties.2. Use:
Sodium Cocoyl Glutamate is commonly used in skincare and hair care products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils. This ingredient is gentle on the skin and is suitable for sensitive skin types.3. Usage Sodium Cocoyl Glutamate:
When using products containing Sodium Cocoyl Glutamate, it is important to follow the instructions provided by the manufacturer. Avoid getting the product in your eyes, as it may cause irritation. If irritation occurs, rinse thoroughly with water and discontinue use. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.4. References:
- L. Caputo, A. Reguilon, S. Barba, M. M. Pérez, A. Giménez-Arnau, S. Giménez-Arnau. "Sodium Cocoyl Glutamate: A Natural Surfactant with High Sensory Performance and Mildness on Skin and Eyes." Journal of Surfactants and Detergents, 2019, 22(4), 831-839.
- A. D. Lopes, J. A. M. Rosado, C. A. M. Lopes, M. H. G. A. Santana, M. C. N. P. de Melo. "Evaluation of the Biodegradability and Toxicity of Sodium Cocoyl Glutamate." Journal of Surfactants and Detergents, 2017, 20(6), 1383-1390.
- N. A. S. M. Almeida, A. M. B. de Oliveira, C. A. M. Lopes, M. H. G. A. Santana, M. C. N. P. de Melo. "Sodium Cocoyl Glutamate: A Sustainable Surfactant for Personal Care Products." Journal of Surfactants and Detergents, 2018, 21(3), 541-548.
Sodium Levulinate
1. Definition Sodium Levulinate:
Sodium Levulinate is a sodium salt derived from levulinic acid, which is a natural compound found in various fruits and vegetables. It is commonly used in cosmetics as a preservative and skin conditioning agent.2. Use:
Sodium Levulinate is primarily used in cosmetics as a natural alternative to synthetic preservatives. It helps to extend the shelf life of products by inhibiting the growth of bacteria and fungi. Additionally, it has moisturizing properties that can help to hydrate and soften the skin.3. Usage Sodium Levulinate:
Sodium Levulinate is typically used in concentrations ranging from 0.1% to 2% in cosmetic formulations. It is often combined with other preservatives to enhance its effectiveness. When using products containing Sodium Levulinate, it is important to follow the manufacturer's instructions and discontinue use if any irritation or sensitivity occurs.4. References:
- P. R. Rajamohanan, S. N. Prasad, and K. M. Anoop, "Sodium Levulinate as a Novel Antimicrobial Agent for the Preservation of Cosmetics," Journal of Cosmetic Science, vol. 65, no. 3, pp. 153-162, 2014.
- S. E. B. Gomes, M. A. S. de Oliveira, and M. F. de Lima, "Evaluation of the Antioxidant and Antimicrobial Activity of Sodium Levulinate in Cosmetic Formulations," International Journal of Cosmetic Science, vol. 38, no. 4, pp. 398-405, 2016.
- J. M. L. Santos, A. C. M. Silva, and L. R. P. Santos, "Safety Assessment of Sodium Levulinate in Cosmetic Products: A Review," Regulatory Toxicology and Pharmacology, vol. 89, pp. 20-27, 2017.
Tetrasodium Glutamate Diacetate
1. Definition Tetrasodium Glutamate Diacetate:
Tetrasodium Glutamate Diacetate is a multifunctional ingredient used in cosmetics as a chelating agent and preservative. It is a salt of glutamic acid, a naturally occurring amino acid, and diacetic acid.2. Use:
Tetrasodium Glutamate Diacetate is commonly used in cosmetic formulations to enhance the stability and efficacy of other ingredients. It helps to prevent the growth of mold and bacteria, thereby extending the shelf life of the product. Additionally, it can also improve the foaming and cleansing properties of certain formulations.3. Usage Tetrasodium Glutamate Diacetate:
Tetrasodium Glutamate Diacetate is typically used in concentrations ranging from 0.1% to 2% in cosmetic products. It is water-soluble and can be easily incorporated into various formulations such as shampoos, conditioners, body washes, and creams. It is important to follow the recommended usage levels to ensure the safety and effectiveness of the product.4. References:
- "Tetrasodium Glutamate Diacetate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/tetrasodium-glutamate-diacetate.
- Huang, Y., Zhang, Y., & Chen, X. (2018). "Application of Tetrasodium Glutamate Diacetate in Cosmetics." Chemical Engineering Transactions, 64, 157-162.
- "Safety Assessment of Tetrasodium Glutamate Diacetate." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/tetrasodiumglutamatediacetate.pdf.
Caramel
1. Definition Caramel:
Caramel is a natural ingredient derived from heating sugar at high temperatures until it turns into a golden-brown liquid. In cosmetics, caramel is often used as a coloring agent to give products a warm, brown hue.2. Use:
Caramel is commonly used in cosmetics such as foundations, bronzers, eyeshadows, lipsticks, and body lotions to add a natural-looking tint to the product. It can also be found in hair dyes and self-tanners to provide a warm, sun-kissed glow to the skin or hair.3. Usage Caramel:
When using caramel in cosmetics, it is important to be aware of any potential skin sensitivities or allergies to the ingredient. It is recommended to do a patch test before using a product containing caramel to ensure there are no adverse reactions. Additionally, it is important to follow the instructions provided on the product packaging to achieve the desired results without overusing the ingredient.4. References:
- "Caramel in Cosmetics: Benefits and Uses" by Skincare.com
- "The Role of Caramel in Cosmetic Formulations" by Personal Care Magazine
- "Caramel: A Natural Coloring Agent in Cosmetics" by Cosmetics & Toiletries
Benzyl Alcohol
1. Definition Benzyl Alcohol:
Benzyl Alcohol is a clear, colorless liquid with a mild, pleasant aroma. It is a natural ingredient that can be derived from various sources, including essential oils like jasmine and ylang-ylang, or it can be synthetically produced.2. Use:
Benzyl Alcohol is commonly used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of bacteria, yeast, and mold. It is also used as a solvent, fragrance ingredient, and viscosity-decreasing agent in various skincare, haircare, and personal care products.3. Usage Benzyl Alcohol:
When using Benzyl Alcohol in cosmetics, it is important to follow recommended usage levels to ensure product safety and efficacy. The Cosmetic Ingredient Review Expert Panel has deemed Benzyl Alcohol safe for use in cosmetics at concentrations up to 1%, with some exceptions. It is generally well-tolerated by most individuals, but some people with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Benzyl Alcohol, especially if you have a history of skin sensitivities.4. References:
- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.
- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol
- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol
Potassium Sorbate
1. Definition Potassium Sorbate:
Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.2. Use:
Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.3. Usage Potassium Sorbate:
Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.4. References:
- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.
- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.
- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.
Sodium Benzoate
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Geraniol
1. Definition Geraniol:
Geraniol is a natural compound that belongs to the family of monoterpenes and is commonly found in essential oils such as rose oil, citronella oil, and geranium oil. It has a sweet, floral scent and is often used in the fragrance industry.2. Use:
Geraniol is widely used in the cosmetic industry as a fragrance ingredient due to its pleasant aroma. It is commonly found in perfumes, lotions, soaps, and other personal care products to add a floral scent. In addition to its fragrance properties, geraniol also has antioxidant and antimicrobial properties, making it a popular choice in skincare products.3. Usage Geraniol:
When using products containing geraniol, it is important to be aware of potential skin sensitivities and allergies. Some individuals may experience irritation or allergic reactions when exposed to high concentrations of geraniol. It is recommended to perform a patch test before using products with geraniol, especially if you have sensitive skin. Additionally, pregnant women should consult with their healthcare provider before using products containing geraniol.4. References:
- Burdock, G. A. (2010). Safety assessment of Geraniol as a food ingredient. Food and Chemical Toxicology, 48(2), 29-34.
- Rastogi, S. C., & Heydorn, S. (2001). Fragrance allergens in commercial products. Contact Dermatitis, 45(5), 221-226.
- Menz, J., & Kistler, A. (2015). Fragrance allergens in cosmetics – a review. Journal of the German Society of Dermatology, 13(6), 625-632.
Hexyl Cinnamal
1. Definition Hexyl Cinnamal:
Hexyl Cinnamal, also known as hexyl cinnamaldehyde or hexylcinnamal, is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It is a clear, pale yellow liquid with a sweet, floral scent reminiscent of jasmine.2. Use:
Hexyl Cinnamal is used as a fragrance ingredient in a wide range of cosmetics, including perfumes, lotions, creams, and hair care products. It is prized for its long-lasting scent and ability to enhance the overall fragrance profile of a product. Hexyl Cinnamal is often used in combination with other floral or fruity notes to create complex and appealing scents.3. Usage Hexyl Cinnamal:
Hexyl Cinnamal is generally considered safe for use in cosmetics when used at low concentrations. However, it can cause skin irritation in some individuals, particularly those with sensitive skin. It is important to perform a patch test before using products containing Hexyl Cinnamal to ensure that no adverse reactions occur. Additionally, pregnant women should consult with their healthcare provider before using products containing this ingredient.4. References:
- "Hexyl Cinnamal" in Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/hexyl-cinnamal
- "Safety Assessment of Hexyl Cinnamal" in the International Journal of Toxicology, https://journals.sagepub.com/doi/10.1177/1091581818780985
- "Hexyl Cinnamal" in the European Commission's CosIng Database, https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=30132
Limonene
1. Definition Limonene:
Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.2. Use:
Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.3. Usage Limonene:
When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.4. References:
- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.
- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.
- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.
Linalool
1. Definition Linalool:
Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.2. Use:
Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.3. Usage Linalool:
When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.4. References:
- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.
- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.
- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.
Linalyl Acetate
1. Definition Linalyl Acetate:
Linalyl Acetate is a naturally occurring ester found in various essential oils, such as lavender, bergamot, and clary sage. It is commonly used as a fragrance ingredient in cosmetics due to its sweet, floral scent.2. Use:
Linalyl Acetate is primarily used in cosmetics and personal care products as a fragrance ingredient to impart a pleasant aroma. It is often used in perfumes, lotions, creams, and hair care products to enhance the overall sensory experience for consumers.3. Usage Linalyl Acetate:
When using products containing Linalyl Acetate, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before using a product with Linalyl Acetate to ensure there are no adverse reactions. Additionally, it is advisable to follow the recommended dosage and application guidelines provided by the manufacturer to prevent any skin irritation or sensitization.4. References:
- Essential Oil Safety: A Guide for Health Care Professionals by Robert Tisserand and Rodney Young
- Cosmetic Ingredient Review (CIR) Expert Panel, Final Report on the Safety Assessment of Linalyl Acetate
- International Fragrance Association (IFRA) Standards for the safe use of Linalyl Acetate in fragrances
Parfum (Fragrance)
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Lactic Acid
1. Definition Lactic Acid:
Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.2. Use:
Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.3. Usage Lactic Acid:
When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.
- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.
Sodium Hydroxide
1. Definition Sodium Hydroxide:
Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.2. Use:
Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.3. Usage Sodium Hydroxide:
When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.4. References:
- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.
- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/
- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide