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EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Water (Solvent)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger Cleansing
2	-	Citrus Aurantium Amara (Bitter Orange) Oil (Skin Conditioning, Masking, Fragrance, Tonic)
1 2	A	Bisabolol	Promotes Wound Healing Brightening
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
1 2	-	Polyaminopropyl Biguanide (Preservative)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1 3	A	Sodium Benzoate (Masking, Fragrance, Preservative, Anticorrosive)

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Aqua (Water) (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin Moisturizing
1	A	Hexylene Glycol (Solvent, Perfuming, Fragrance, Viscosity Decreasing Agent, Skin Conditioning, Emulsifying, Surfactant)	Cleansing
2 4	A	Poloxamer 184 (Surfactant, Emulsifying)	Cleansing
1	A	Disodium Cocoamphodiacetate (Skin Conditioning, Solvent to dissolve substances insoluble in water, Hair Conditioning, Sufactant, Foam Boosting)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)

Water

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Polysorbate 20

Other Names: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Citrus Aurantium Amara (Bitter Orange) Oil

Function: Skin Conditioning, Masking, Fragrance, Tonic

1. Definition Citrus Aurantium Amara (Bitter Orange) Oil:

Citrus Aurantium Amara (Bitter Orange) Oil is an essential oil derived from the peel of the bitter orange fruit. It is known for its fresh, citrusy scent and is commonly used in cosmetics for its aromatic properties and potential skin benefits.

2. Use:

Bitter Orange Oil is often used in cosmetics as a fragrance ingredient to add a refreshing and uplifting aroma to products. It is also believed to have astringent properties, making it a popular choice for skincare products targeting oily or acne-prone skin. Additionally, the oil is sometimes used in hair care products for its invigorating scent and potential scalp benefits.

3. Usage Citrus Aurantium Amara (Bitter Orange) Oil:

When using products containing Bitter Orange Oil, it is important to be aware of potential skin sensitivities or allergies. It is recommended to perform a patch test before using the product on a larger area of skin to ensure compatibility. As with any essential oil, it is best to dilute Bitter Orange Oil with a carrier oil before applying it directly to the skin to avoid irritation. It is also advisable to avoid using products with Bitter Orange Oil on broken or irritated skin.

4. References:

- Buchbauer G, Jirovetz L, Jager W, Plank C, Dietrich H. Fragrance compounds and essential oils with sedative effects upon inhalation. J Pharm Sci. 1993;82(6):660-4.

- Re L, Barocci S, Sonnino S, et al. Linalool modifies the nicotinic receptor-ion channel kinetics at the mouse neuromuscular junction. Pharmacol Res. 2000;42(2):177-82.

- Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry. 2003;27(1):123-7.

Bisabolol

Other Names: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

Disodium Edta

Other Names: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Polyaminopropyl Biguanide

Function: Preservative

1. Definition Polyaminopropyl Biguanide:

Polyaminopropyl Biguanide (PAPB) is a common preservative used in cosmetics and personal care products. It is a cationic polymer that is effective against a wide range of bacteria, fungi, and yeast.

2. Use:

PAPB is used in cosmetics to prevent microbial contamination and extend the shelf life of products. It is commonly found in skincare products, makeup, shampoos, and conditioners.

3. Usage Polyaminopropyl Biguanide:

When using products containing PAPB, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 0.3%. PAPB should be added to the formulation during the cooling phase to ensure stability and efficacy. It is important to note that PAPB can cause irritation or allergic reactions in some individuals, so it is recommended to perform a patch test before using products containing this preservative.

4. References:

- Kim, H., Lee, H. K., Kim, Y. S., & Kim, Y. H. (2012). Evaluation of the skin irritation potential of cosmetic preservatives using the EpiDerm reconstructed human epidermal model. Journal of toxicology and environmental health. Part A, 75(5), 239-47.

- Draelos, Z. D., & Dover, J. S. (2010). A clinical evaluation of the efficacy and safety of a topical treatment for the signs of skin aging. Journal of cosmetic dermatology, 9(2), 108-12.

- Lode, O., & Moen, L. (2016). Cosmetic preservatives: A review. Journal of cosmetic science, 67(4), 229-44.

Phenoxyethanol

Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Sodium Benzoate

Other Names: natri benzoat

Function: Masking, Fragrance, Preservative, Anticorrosive

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

Glycerin

Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

Hexylene Glycol

Other Names: 2-Methyl-2; 4-pentanediol

Function: Solvent, Perfuming, Fragrance, Viscosity Decreasing Agent, Skin Conditioning, Emulsifying, Surfactant

1. Definition Hexylene Glycol:

Hexylene Glycol is a clear, colorless liquid that belongs to the class of chemicals known as glycols. It is commonly used in cosmetics as a solvent, emollient, and humectant.

2. Use:

Hexylene Glycol is used in a variety of cosmetic products such as skincare, haircare, and makeup. It helps to dissolve other ingredients, improve the texture of products, and provide moisturizing benefits to the skin and hair.

3. Usage Hexylene Glycol:

Hexylene Glycol is typically used in concentrations of 1-10% in cosmetic formulations. It is considered to be safe for use in cosmetics when used as directed. However, it is important to follow the recommended guidelines for usage to avoid any potential skin irritation or allergic reactions.

Precautions when using Hexylene Glycol in cosmetics include conducting a patch test before using a new product containing the ingredient, avoiding contact with the eyes, and discontinuing use if any irritation occurs. It is also recommended to store products containing Hexylene Glycol in a cool, dry place away from direct sunlight to maintain their stability and efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. "Final Report on the Safety Assessment of Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol." International Journal of Toxicology, vol. 20, no. 3, 2001, pp. 61-75.

- Personal Care Products Council. "Hexylene Glycol." The Personal Care Products Council, www.cosmeticsinfo.org/ingredient/hexylene-glycol.

- PubChem. "Hexylene Glycol." National Center for Biotechnology Information, U.S. National Library of Medicine, pubchem.ncbi.nlm.nih.gov/compound/hexylene_glycol.

Poloxamer 184

Function: Surfactant, Emulsifying

1. Definition Poloxamer 184:

Poloxamer 184 is a nonionic surfactant and emulsifier that is commonly used in cosmetics and personal care products. It is a copolymer of ethylene oxide and propylene oxide, with a molecular weight of around 8400 g/mol.

2. Use:

Poloxamer 184 is used in cosmetics as a solubilizer, emulsifier, and stabilizer. It helps to improve the texture and spreadability of products, as well as enhance the overall performance of formulations. It is often found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Poloxamer 184:

When using products containing Poloxamer 184, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is recommended to perform a patch test before using a product with Poloxamer 184, especially if you have sensitive skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Poloxamers." Cosmetics Info, www.cosmeticsinfo.org/ingredient/poloxamers.

- "Poloxamer 184." Truth in Aging, www.truthinaging.com/ingredients/poloxamer-184.

- "Poloxamers in Cosmetics." Personal Care Magazine, www.personalcaremagazine.com/story/21958/poloxamers-in-cosmetics.

Disodium Cocoamphodiacetate

Function: Skin Conditioning, Solvent to dissolve substances insoluble in water, Hair Conditioning, Sufactant, Foam Boosting

1. Definition Disodium Cocoamphodiacetate:

Disodium Cocoamphodiacetate is a mild surfactant derived from coconut oil. It is a water-soluble amphoteric surfactant that is commonly used in cosmetics and personal care products for its gentle cleansing and foaming properties.

2. Use:

Disodium Cocoamphodiacetate is used in a wide range of cosmetic products such as shampoos, body washes, facial cleansers, and makeup removers. It helps to cleanse the skin and hair by removing dirt, oil, and impurities without stripping away natural oils or causing irritation. It also helps to create a rich lather and improve the overall texture of the product.

3. Usage Disodium Cocoamphodiacetate:

Disodium Cocoamphodiacetate is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is considered to be safe for use in skincare products and is suitable for all skin types, including sensitive skin. However, as with any cosmetic ingredient, it is important to perform a patch test before using products containing Disodium Cocoamphodiacetate to ensure that it does not cause any adverse reactions.

4. References:

- "Disodium Cocoamphodiacetate." The Derm Review, www.thedermreview.com/disodium-cocoamphodiacetate/.

- "Ingredient Spotlight: Disodium Cocoamphodiacetate." The Eco Well, theecowell.com/ingredient-spotlight-disodium-cocoamphodiacetate/.

- "Disodium Cocoamphodiacetate." Truth in Aging, www.truthinaging.com/ingredients/disodium-cocoamphodiacetate.