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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 4 | - | (Emollient, Hair Conditioning, Skin Protecting, Uv Absorber, Moisturising, Skin-Conditioning Agent - Occlusive) | Bad for oily skin Moisturizing |
| 1 3 | - | (Solvent, Perfuming, Fragrance, Hair Conditioning, Skin Protecting, Skin Conditioning, Emollient, Antistatic Agent) | Moisturizing |
| 1 | A | (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous) | Cleansing |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 3 | B | (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous) | Good for dry skin |
| 3 | A | (Solvent, Hair Conditioning, Skin Conditioning, Emollient) | |
| 3 | B | (Emulsifying, Surfactant) | Fungal Acne Trigger Cleansing |
| 1 | - | (Skin Conditioning, Antimicrobial, Soothing, Tonic, Astringent, Anticaking Agent) | |
| 1 | - | (Skin Conditioning, Stabilising, Soothing, Tonic, Astringent, Refreshing) | |
| - | A | (Skin Conditioning) | |
| 1 | - | (Masking, Fragrance) | |
| 1 | - | (Skin Conditioning, Drug Astringent - Skin Protecting) | Good for oily skin |
| 1 | - | (Skin Conditioning) | |
| 1 | - | (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming) | |
| 1 | A | (Humectant, Skin Conditioning) | Good for dry skin Promotes Wound Healing |
| 1 | - | (Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer) | |
| 2 | A | (Deodorant, Skin Conditioning) | |
| 1 | A | (Surfactant, Cleansing, Foaming) | Cleansing |
| 2 | A | (Solvent, Hair Conditioning, Skin Conditioning, Emollient) | |
| 1 4 | B | (Denaturant , pH adjusting agent, pH adjusting agent) | |
| 1 2 | A | (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent) | Anti Aging Bad for sensitive skin |
| 1 | A | (Masking, pH adjusting agent, pH adjusting agent, Chelating) | |
| 1 | - | Good for dry skin Anti Aging | |
| 2 4 | A | (Fragrance, Preservative) | |
| 4 5 | - | (Solvent, Perfuming, Deodorant) | Allergen |
| 3 5 | - | (Masking, Fragrance, Denaturant , Tonic) | Allergen |
| 3 | - | (Masking, Deodorant, Fragrance) | Allergen |
| 1 | - | (Masking, Perfuming) | Allergen |
| 4 5 | - | (Masking, Fragrance) | Allergen |
| 3 5 | - | (Masking, Fragrance, Tonic) | Allergen |
| 3 | - | (Masking, Fragrance) | Allergen |
| 8 | - | (Masking, Perfuming, Deodorant) | Fragrance-free |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 3 | - | (Antiacne Agent, Oxidising Agent) | Acne fighting |
| 1 | - | (Solvent) | |
| 1 | - | (Solvent, Fragrance, Humectant) | Anti Aging |
| 1 | A | (Emollient, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 3 | A | (Surfactant, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 3 | A | (Surfactant) | Fungal Acne Trigger Cleansing |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 1 3 | A | (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent) | Moisturizing |
| 1 | A | (Opacifying, Viscosity Controlling, Absorbent, Anticaking Agent, Viscosity Increasing Agent, Slip Modifier) | |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming) | |
| 4 6 | A | (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Preservative, External Analgesic ) | Allergen |
| 2 3 | - | (pH adjusting agent, pH adjusting agent, Denaturant ) | |
| 1 | A | (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning) | |
| 1 3 | A | (Masking, Fragrance, Preservative, pH adjusting agent, Bulking Agent) | Bad for sensitive skin |
| 2 | A | (Fragrance, Preservative) | |
| 1 3 | - | (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying) | UV Protection Good for sensitive skin |
Aqua (Water)
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Paraffinum Liquidum
1. Definition White Petrolatum:
White Petrolatum, also known as white petroleum jelly or white soft paraffin, is a purified mixture of semi-solid hydrocarbons derived from petroleum. It is a colorless and odorless substance that is commonly used in skincare and cosmetic products for its moisturizing and protective properties.2. Use:
White Petrolatum is used in a wide range of cosmetic products such as lip balms, lotions, creams, ointments, and hair care products. It is known for its ability to create a protective barrier on the skin, locking in moisture and preventing water loss. This helps to soothe and hydrate dry, chapped skin, making it a popular ingredient in products designed to treat dryness and irritation.3. Usage White Petrolatum:
When using products containing White Petrolatum, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for external use, but precautions should be taken to avoid ingestion or contact with eyes. Individuals with sensitive skin or allergies should perform a patch test before using products containing White Petrolatum to ensure compatibility with their skin.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 8003, White Petrolatum. [https://pubchem.ncbi.nlm.nih.gov/compound/White-petrolatum]
- Cosmetics Info. White Petrolatum. [https://www.cosmeticsinfo.org/ingredient/white-petrolatum]
- Personal Care Products Council. White Petrolatum. [https://www.personalcarecouncil.org/ingredient-info/white-petrolatum/]
Mineral Oil
1. Definition Mineral Oil:
Mineral oil is a colorless and odorless oil derived from petroleum. It is a common ingredient in skincare and cosmetic products due to its ability to lock in moisture and create a protective barrier on the skin.2. Use:
Mineral oil is used in cosmetics as an emollient to soften and smooth the skin. It is often found in moisturizers, lip balms, and makeup products to provide hydration and improve the overall texture of the skin.3. Usage Mineral Oil:
When using products containing mineral oil, it is important to note that it may clog pores for some individuals, leading to breakouts or irritation. It is recommended to perform a patch test before applying mineral oil-based products to the entire face or body to ensure compatibility with your skin.4. References:
- "Mineral Oil: The Good, the Bad, and the Ugly" by Paula Begoun
- "Mineral Oil in Skin Care: Good or Bad?" by Dr. Cynthia Bailey
- "The Truth About Mineral Oil" by Dr. Leslie Baumann
Cetearyl Alcohol
1. Definition Cetearyl Alcohol:
Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.2. Use:
Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.3. Usage Cetearyl Alcohol:
When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.4. References:
- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html
- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/
- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf
Cetyl Alcohol
1. Definition Cetyl Alcohol:
Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.2. Use:
Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.3. Usage Cetyl Alcohol:
When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.4. References:
- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)
- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)
- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)
Propylene Glycol
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Cyclopentasiloxane
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Polysorbate 60
1. Definition Polysorbate 60:
Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.2. Use:
Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.3. Usage Polysorbate 60:
When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.4. References:
- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.
- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.
- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.
Hedera Helix (Ivy) Extract
1. Definition Hedera Helix (Ivy) Extract:
Hedera Helix (Ivy) Extract is derived from the leaves of the common ivy plant. It is known for its soothing, astringent, and anti-inflammatory properties, making it a popular ingredient in skincare products.2. Use:
Hedera Helix (Ivy) Extract is commonly used in cosmetics for its ability to improve skin texture and tone. It is also known for its antioxidant properties, which help protect the skin from environmental stressors and premature aging. Additionally, Ivy Extract is often included in products designed to reduce inflammation and redness, making it suitable for sensitive or irritated skin.3. Usage Hedera Helix (Ivy) Extract:
Hedera Helix (Ivy) Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effects. When using products containing Ivy Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to larger areas of the skin to ensure compatibility.4. References:
- Fernandes, L. (2018). The benefits of ivy extract for skin. Retrieved from https://www.healthline.com/health/ivy-extract-for-skin
- Kim, S. H., et al. (2014). Anti-inflammatory and anti-oxidative effects of Hedera helix L. extract on lipopolysaccharide-stimulated RAW 264.7 cells. Retrieved from https://pubmed.ncbi.nlm.nih.gov/24679917/
- Singh, S., et al. (2017). Anti-inflammatory and analgesic activity of Hedera helix Linn. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661189/
Ruscus Aculeatus Root Extract
1. Definition Ruscus Aculeatus Root Extract:
Ruscus Aculeatus Root Extract, also known as Butcher's Broom Extract, is derived from the roots of the Ruscus aculeatus plant. This plant is native to the Mediterranean region and has been used for centuries in traditional medicine for its anti-inflammatory and vasoconstrictive properties.2. Use:
Ruscus Aculeatus Root Extract is commonly used in cosmetics for its ability to improve circulation, reduce inflammation, and strengthen blood vessels. It is often included in skincare products designed to target issues such as dark circles, puffiness, and redness. Additionally, it is known for its soothing and calming effects on the skin, making it a popular ingredient in products for sensitive or reactive skin types.3. Usage Ruscus Aculeatus Root Extract:
When using products containing Ruscus Aculeatus Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. As with any new skincare ingredient, it is advisable to consult with a dermatologist or skincare professional if you have any concerns about its use.4. References:
- Arnaud, L., et al. (2009). Butcher's Broom Extract: A Multifaceted Ingredient for the Cosmetic Industry. Cosmetic Science Technology, 1-4.
- Guarrera, P. M., & Savo, V. (2013). Perceived health properties of wild and cultivated food plants in local and popular traditions of Italy: A review. Journal of Ethnopharmacology, 146(3), 659-680.
- Piazza, C., et al. (2017). Ruscus Aculeatus Extract: A Review of Its Phytochemistry and Pharmacology. Phytotherapy Research, 31(12), 1853-1869.
Hypericum Perforatum Flower/Leaf/Stem Extract
1. Definition Hypericum Perforatum Flower/Leaf/Stem Extract:
Hypericum Perforatum Flower/Leaf/Stem Extract, also known as St. John's Wort extract, is derived from the flowering plant Hypericum perforatum. This extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and soothing properties.2. Use:
Hypericum Perforatum Flower/Leaf/Stem Extract is used in cosmetics to help improve the overall appearance of the skin. It is known for its ability to reduce redness, calm irritation, and protect the skin from environmental stressors. This extract is often included in skincare products such as serums, creams, and masks to help promote a healthier complexion.3. Usage Hypericum Perforatum Flower/Leaf/Stem Extract:
When using cosmetics containing Hypericum Perforatum Flower/Leaf/Stem Extract, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to avoid using products with this extract if you are pregnant or breastfeeding, as it may have hormonal effects.4. References:
- Schempp, C. M., & Schöpf, E. (2002). Topical treatment of atopic dermatitis with St. John's Wort cream—a randomized, placebo controlled, double blind half-side comparison. Phytomedicine, 9(3), 131-137.
- Butterweck, V. (2003). Mechanism of action of St John's wort in depression: what is known?. CNS drugs, 17(8), 539-562.
- Linde, K., Berner, M. M., & Kriston, L. (2008). St John's wort for major depression. Cochrane Database of Systematic Reviews, (4).
Heterotheca Inuloides (Arnica Mexicana) Flower Extract
1. Definition Heterotheca Inuloides Flower Extract:
Heterotheca Inuloides Flower Extract, also known as Arnica Flower Extract, is derived from the bright yellow flowers of the Heterotheca inuloides plant. This extract is rich in antioxidants, flavonoids, and essential oils, making it a popular ingredient in skincare products.2. Use:
Heterotheca Inuloides Flower Extract is commonly used in cosmetics for its anti-inflammatory and soothing properties. It is known to help reduce redness, calm irritated skin, and promote overall skin health. Additionally, this extract is often included in products designed to target bruising, swelling, and muscle soreness.3. Usage Heterotheca Inuloides Flower Extract:
When using products containing Heterotheca Inuloides Flower Extract, it is important to patch test first to check for any potential allergic reactions. This extract is generally considered safe for topical use, but it is always recommended to follow the instructions provided by the manufacturer. Avoid contact with eyes and mucous membranes, and discontinue use if any irritation occurs.4. References:
- Gavrilova, V., & Kajdzanoska, M. (2015). Extraction of bioactive compounds from arnica flowers by different solvents. Journal of Chemical Technology and Metallurgy, 50(4), 399-406.
- Lopes, G., Pinto, E., Andrade, P. B., & Valentão, P. (2017). Insights into the chemical composition of arnica (Heterotheca inuloides Cass.) under abiotic stress. Industrial Crops and Products, 97, 244-252.
- Sánchez-Medina, A., González-Andrade, M., & Martínez-Vázquez, M. (2011). Arnica (Heterotheca inuloides Cass) as a functional ingredient for cosmetic products. Revista Mexicana de Ciencias Farmacéuticas, 42(2), 37-42.
Hamamelis Virginiana (Witch Hazel) Water
1. Definition Hamamelis Virginiana (Witch Hazel) Water:
Hamamelis Virginiana (Witch Hazel) Water is a natural astringent derived from the Witch Hazel shrub, native to North America. It is commonly used in skincare products for its soothing and toning properties.2. Use:
Witch Hazel Water is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products such as toners, cleansers, and moisturizers. It is often used to help reduce redness, inflammation, and irritation, making it suitable for all skin types, including sensitive skin.3. Usage Hamamelis Virginiana (Witch Hazel) Water:
Witch Hazel Water can be applied directly to the skin using a cotton pad or spray bottle. It can be used as a toner after cleansing the skin to help tighten pores and remove excess oil. It can also be used as a spot treatment for acne or as a soothing mist throughout the day to refresh the skin. It is important to patch test before applying to the entire face to ensure there is no allergic reaction.4. References:
- Lee, J. H., Choi, H. R., & Kim, H. K. (2017). Anti-inflammatory and anti-oxidant effects of a combination of flavonoids and saponins from the roots of Platycodon grandiflorum in RAW 264.7 cells. Journal of Pharmacy and Pharmacology, 69(10), 1349-1358.
- Thring, T. S., Hili, P., & Naughton, D. P. (2009). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 6(1), 1-11.
- Yoon, J. Y., Kwon, H. H., Min, S. U., Thiboutot, D. M., & Suh, D. H. (2013). Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. Journal of Investigative Dermatology, 133(2), 429-440.
Aesculus Hippocastanum (Horse Chestnut) Seed Extract
1. Definition Aesculus Hippocastanum (Horse Chestnut) Seed Extract:
Aesculus Hippocastanum (Horse Chestnut) Seed Extract is a natural ingredient derived from the seeds of the horse chestnut tree. It is known for its anti-inflammatory, antioxidant, and skin conditioning properties.2. Use:
Horse chestnut seed extract is commonly used in cosmetics for its ability to improve the appearance of skin by reducing inflammation, redness, and puffiness. It is also believed to help strengthen blood vessels and improve circulation, making it beneficial for treating conditions such as varicose veins and dark circles under the eyes.3. Usage Aesculus Hippocastanum (Horse Chestnut) Seed Extract:
Horse chestnut seed extract is typically found in skincare products such as creams, serums, and eye treatments. It can be applied directly to the skin or incorporated into formulations to target specific skin concerns. When using products containing horse chestnut seed extract, it is important to follow the manufacturer's instructions and perform a patch test to check for any potential allergic reactions.4. References:
- 1. Schempp CM, Lüdtke R, Winghofer B, Simon JC. Effect of topical application of a cream containing the extract of Aesculus hippocastanum on the intensity of blue and red skin discolorations. Int J Cosmet Sci. 2005 Jun;27(3):183-7. doi: 10.1111/j.1467-2494.2005.00269.x. PMID: 18492112.
- 2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;2012(11):CD003230. doi: 10.1002/14651858.CD003230.pub4. PMID: 23152216; PMCID: PMC6513435.
- 3. Facino RM, Carini M, Stefani R, Aldini G, Saibene L. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharm (Weinheim). 1995 Nov;328(11):720-4. doi: 10.1002/ardp.19953281110. PMID: 8552953.
Soluble Collagen
1. Definition Soluble Collagen:
Soluble Collagen is a type of collagen that has been hydrolyzed to break down the protein into smaller peptides, making it water-soluble and easier for the skin to absorb. It is commonly derived from animal sources such as fish or bovine skin.2. Use:
Soluble Collagen is often used in cosmetics for its moisturizing and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it can help to strengthen the skin barrier and protect against environmental stressors.3. Usage Soluble Collagen:
Soluble Collagen can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or as part of a skincare regimen. It is important to follow the instructions on the product packaging and to perform a patch test before using, especially if you have sensitive skin. Some individuals may experience allergic reactions or irritation when using products containing collagen, so it is best to consult with a dermatologist before incorporating it into your routine.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Kim, H. J., Kim, J. H., & Lee, H. S. (2017). Soluble collagen isolated from the skin of Nile tilapia (Oreochromis niloticus): extraction, characterization, and study of antioxidant properties. Journal of Food Science and Technology, 54(13), 4261-4270.
- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. The American Journal of Pathology, 168(6), 1861-1868.
Sodium Hyaluronate
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Sorbitol
1. Definition Sorbitol:
Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.2. Use:
Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.3. Usage Sorbitol:
Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol
- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol
- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol
Ethylhexylglycerin
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Sodium Cetearyl Sulfate
1. Definition Sodium Cetearyl Sulfate:
Sodium Cetearyl Sulfate is a surfactant and emulsifying agent commonly used in cosmetics and personal care products. It is a combination of cetearyl alcohol and sulfuric acid, which helps to cleanse and emulsify oils and dirt from the skin.2. Use:
Sodium Cetearyl Sulfate is used in a variety of cosmetic products such as creams, lotions, shampoos, and cleansers. It helps to stabilize and emulsify the ingredients in the product, allowing for a smooth and even application on the skin or hair. It also helps to enhance the cleansing properties of the product, making it more effective in removing impurities.3. Usage Sodium Cetearyl Sulfate:
When using products containing Sodium Cetearyl Sulfate, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. It is recommended to avoid getting the product in contact with the eyes, as it may cause irritation. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.4. References:
- "Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol as Used in Cosmetics." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/cetearyl-alcohol.
- "Cetearyl Alcohol and Cetearyl Glucoside." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol-and-cetearyl-glucoside.
- "Sodium Cetearyl Sulfate." Truth in Aging, www.truthinaging.com/ingredients/sodium-cetearyl-sulfate.
Cyclohexasiloxane
1. Definition Cyclohexasiloxane:
Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.2. Use:
Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.3. Usage Cyclohexasiloxane:
Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.
- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.
- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.
Sodium Hydroxide
1. Definition Sodium Hydroxide:
Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.2. Use:
Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.3. Usage Sodium Hydroxide:
When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.4. References:
- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.
- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/
- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide
Citric Acid
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
Sodium Citrate
1. Definition Sodium Citrate:
Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.2. Use:
Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.3. Usage Sodium Citrate:
When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.4. References:
- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.
- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.
- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.
Tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Limonene
1. Definition Limonene:
Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.2. Use:
Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.3. Usage Limonene:
When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.4. References:
- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.
- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.
- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.
Eugenol
1. Definition Eugenol:
Eugenol is a naturally occurring phenylpropene compound found in essential oils such as clove oil, nutmeg, cinnamon, and bay leaf. It is known for its pleasant aroma and is commonly used in the fragrance industry.2. Use:
Eugenol is widely used in cosmetics for its fragrance and flavoring properties. It is often added to perfumes, soaps, lotions, and hair care products to provide a warm, spicy scent. Additionally, eugenol is used as a natural preservative due to its antimicrobial properties.3. Usage Eugenol:
When using cosmetics containing eugenol, it is important to be aware of potential skin sensitization and irritation. Eugenol has been identified as a contact allergen, so individuals with sensitive skin or allergies may experience adverse reactions. It is recommended to perform a patch test before using products with eugenol to determine if any sensitivities exist. Additionally, it is advised to avoid using products with high concentrations of eugenol on broken or damaged skin to prevent further irritation.4. References:
- Prashar, A., Locke, I. C., & Evans, C. S. (2006). Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Proliferation, 39(4), 241-248.
- Jirovetz, L., Buchbauer, G., Shafi, M. P., & Kaniampady, M. M. (2006). Chemical composition and antimicrobial activities of the essential oil of Eugenia caryophyllata. International Journal of Aromatherapy, 16(1), 41-47.
- Valente, J., Zuzarte, M., Gonçalves, M. J., Lopes, M. C., Cavaleiro, C., Salgueiro, L., & Cruz, M. T. (2013). Antifungal, antioxidant and anti-inflammatory activities of Oenanthe crocata L. essential oil. Food and Chemical Toxicology, 62, 349-354.
Linalool
1. Definition Linalool:
Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.2. Use:
Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.3. Usage Linalool:
When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.4. References:
- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.
- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.
- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.
Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde
1. Definition Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde:
Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde, also known as Lyral, is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It is a clear, colorless liquid with a floral scent and is often used to add a fresh and clean aroma to various products.2. Use:
Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde is primarily used as a fragrance ingredient in a wide range of cosmetic products, including perfumes, lotions, creams, and hair care products. It is valued for its long-lasting scent and ability to enhance the overall fragrance profile of a product.3. Usage Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde:
When using products containing Hydroxyisohexyl 3 Cyclohexene Carboxaldehyde, it is important to be aware of potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or allergic reactions when exposed to this fragrance compound. It is recommended to perform a patch test before using products with this ingredient and to discontinue use if any adverse reactions occur.4. References:
- SCCS (Scientific Committee on Consumer Safety). Opinion on Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. European Commission, 2018.
- CosmeticsInfo.org. Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. https://cosmeticsinfo.org/ingredient/hydroxyisohexyl-3-cyclohexene-carboxaldehyde
- Personal Care Council. Safety Assessment of Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. Cosmetic Ingredient Review, 2013.
Coumarin
1. Definition Coumarin:
Coumarin is a fragrant organic compound that can be found naturally in plants such as tonka beans, sweet clover, and cassia cinnamon. It is commonly used in the fragrance industry due to its sweet, vanilla-like scent.2. Use:
Coumarin is primarily used as a fragrance ingredient in cosmetics, particularly in perfumes, colognes, and lotions. Its sweet aroma adds a warm and comforting note to various beauty products, enhancing their overall scent profile.3. Usage Coumarin:
When using cosmetics containing coumarin, it is important to be aware of potential sensitivities or allergies to this compound. Some individuals may experience skin irritation or allergic reactions when exposed to high concentrations of coumarin. It is recommended to perform a patch test before using products with coumarin extensively, especially if you have sensitive skin.4. References:
- European Commission Scientific Committee on Consumer Safety. (2016). Opinion on Coumarin. Retrieved from https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_199.pdf
- Cosmetic Ingredient Review. (2006). Final Report on the Safety Assessment of Coumarin. Retrieved from https://www.cir-safety.org/sites/default/files/coumarin.pdf
- U.S. Food and Drug Administration. (2018). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=310.545
Geraniol
1. Definition Geraniol:
Geraniol is a natural compound that belongs to the family of monoterpenes and is commonly found in essential oils such as rose oil, citronella oil, and geranium oil. It has a sweet, floral scent and is often used in the fragrance industry.2. Use:
Geraniol is widely used in the cosmetic industry as a fragrance ingredient due to its pleasant aroma. It is commonly found in perfumes, lotions, soaps, and other personal care products to add a floral scent. In addition to its fragrance properties, geraniol also has antioxidant and antimicrobial properties, making it a popular choice in skincare products.3. Usage Geraniol:
When using products containing geraniol, it is important to be aware of potential skin sensitivities and allergies. Some individuals may experience irritation or allergic reactions when exposed to high concentrations of geraniol. It is recommended to perform a patch test before using products with geraniol, especially if you have sensitive skin. Additionally, pregnant women should consult with their healthcare provider before using products containing geraniol.4. References:
- Burdock, G. A. (2010). Safety assessment of Geraniol as a food ingredient. Food and Chemical Toxicology, 48(2), 29-34.
- Rastogi, S. C., & Heydorn, S. (2001). Fragrance allergens in commercial products. Contact Dermatitis, 45(5), 221-226.
- Menz, J., & Kistler, A. (2015). Fragrance allergens in cosmetics – a review. Journal of the German Society of Dermatology, 13(6), 625-632.
Hexyl Cinnamal
1. Definition Hexyl Cinnamal:
Hexyl Cinnamal, also known as hexyl cinnamaldehyde or hexylcinnamal, is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It is a clear, pale yellow liquid with a sweet, floral scent reminiscent of jasmine.2. Use:
Hexyl Cinnamal is used as a fragrance ingredient in a wide range of cosmetics, including perfumes, lotions, creams, and hair care products. It is prized for its long-lasting scent and ability to enhance the overall fragrance profile of a product. Hexyl Cinnamal is often used in combination with other floral or fruity notes to create complex and appealing scents.3. Usage Hexyl Cinnamal:
Hexyl Cinnamal is generally considered safe for use in cosmetics when used at low concentrations. However, it can cause skin irritation in some individuals, particularly those with sensitive skin. It is important to perform a patch test before using products containing Hexyl Cinnamal to ensure that no adverse reactions occur. Additionally, pregnant women should consult with their healthcare provider before using products containing this ingredient.4. References:
- "Hexyl Cinnamal" in Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/hexyl-cinnamal
- "Safety Assessment of Hexyl Cinnamal" in the International Journal of Toxicology, https://journals.sagepub.com/doi/10.1177/1091581818780985
- "Hexyl Cinnamal" in the European Commission's CosIng Database, https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=30132
Parfum (Fragrance)
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Benzoyl Peroxide (10%)
1. Definition Benzoyl Peroxide:
Benzoyl Peroxide is a topical medication commonly used in skincare products to treat acne. It works by reducing the amount of acne-causing bacteria on the skin and helping to unclog pores.2. Use:
Benzoyl Peroxide is primarily used in over-the-counter and prescription acne treatments, such as creams, gels, and washes. It is often recommended for mild to moderate acne and can help to reduce inflammation, redness, and the number of pimples on the skin.3. Usage Benzoyl Peroxide:
When using products containing Benzoyl Peroxide, it is important to follow the instructions provided by the manufacturer or healthcare provider. Typically, a small amount of the product is applied to clean, dry skin once or twice daily. It is important to start with a lower concentration of Benzoyl Peroxide and gradually increase as needed to avoid irritation. It is also recommended to use sunscreen when using products containing Benzoyl Peroxide, as it can increase sensitivity to the sun.4. References:
- Draelos, Z. D. (2016). Over-the-counter acne treatments. Dermatologic clinics, 34(2), 175-184.
- Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Bhushan, R. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.
- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Layton, A. M. (2019). Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 81(3), 775-789.
Gluconolactone
1. Definition Gluconolactone:
Gluconolactone is a polyhydroxy acid (PHA) that is derived from natural sources such as fruits and honey. It is a gentle exfoliant and humectant that helps to improve skin texture and hydration.2. Use:
Gluconolactone is commonly used in skincare products such as exfoliants, toners, and moisturizers. It helps to gently exfoliate the skin by removing dead skin cells, unclogging pores, and promoting cell turnover. Additionally, it has hydrating properties that help to attract and retain moisture, making it suitable for all skin types, including sensitive skin.3. Usage Gluconolactone:
When using skincare products containing Gluconolactone, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration to assess skin tolerance and gradually increase the frequency of use as needed. It is also important to use sunscreen daily when using products with Gluconolactone, as it can increase skin sensitivity to UV radiation.4. References:
- Bhatia, A., & Maisuria, V. (2016). Polyhydroxy acids: A new generation of hydroxy acids. International Journal of Research in Cosmetic Science, 6(1), 1-5.
- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.
- Obagi, Z. E., & Obagi, S. (2003). Chemical peeling and aging skin. Journal of Geriatric Dermatology, 11(2), 67-71.
Glyceryl Stearate
1. Definition Glyceryl Stearate:
Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.2. Use:
Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.3. Usage Glyceryl Stearate:
When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.4. References:
- "Glyceryl Stearate" by The Personal Care Products Council
- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review
- "Glyceryl Stearate" by Paula's Choice Skincare
Peg 40 Stearate
1. Definition Peg 40 Stearate:
Peg 40 Stearate is a polyethylene glycol derivative of stearic acid that is commonly used in cosmetics as an emulsifier and surfactant. It helps to blend oil and water-based ingredients together, creating stable and uniform formulations.2. Use:
Peg 40 Stearate is primarily used in cosmetics and personal care products such as creams, lotions, and makeup. It helps to improve the texture and consistency of products, making them easier to apply and spread on the skin. Additionally, it can enhance the solubility of other ingredients in the formulation, increasing their effectiveness.3. Usage Peg 40 Stearate:
When using products containing Peg 40 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use but may cause irritation or allergic reactions in some individuals, especially those with sensitive skin. It is recommended to perform a patch test before using a new product to check for any adverse reactions.4. References:
- "PEG-40 Stearate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/peg-40-stearate
- "PEG-40 Stearate" by Truth In Aging, https://www.truthinaging.com/ingredients/peg-40-stearate
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" by FDA, https://www.fda.gov/cosmetics/cosmetic-ingredients/polyethylene-glycol-peg-compounds-cosmetics
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Peg 100 Stearate
1. Definition Peg 100 Stearate:
Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.2. Use:
Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.3. Usage Peg 100 Stearate:
When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.4. References:
- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.
- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.
Dimethicone
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Magnesium Aluminum Silicate
1. Definition Magnesium Aluminum Silicate:
Magnesium Aluminum Silicate is a naturally occurring mineral derived from refined and purified clay. It is commonly used in cosmetics as a thickening agent, stabilizer, and opacifying agent.2. Use:
Magnesium Aluminum Silicate is primarily used in cosmetic formulations to improve the texture and consistency of products such as creams, lotions, and makeup. It helps to create a smooth and creamy texture, while also providing a matte finish. Additionally, it can help to absorb excess oil and reduce shine on the skin.3. Usage Magnesium Aluminum Silicate:
Magnesium Aluminum Silicate should be used in cosmetics according to the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is important to perform a patch test before using products containing this ingredient, especially for those with sensitive skin. It is recommended to avoid inhaling the powder form of Magnesium Aluminum Silicate and to wash hands thoroughly after handling.4. References:
- Cosmetics Info. (n.d.). Magnesium Aluminum Silicate. https://cosmeticsinfo.org/ingredient/magnesium-aluminum-silicate
- Personal Care Council. (2019). International Cosmetic Ingredient Dictionary and Handbook. Washington, DC: Personal Care Products Council.
- Loretz, L., Api, A. M., Babcock, L., Barraj, L., Burdick, J., Cater, K. C., ... & Wilcox, D. K. (2008). Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadow. Food and Chemical Toxicology, 46(5), 1516-1524.
Xanthan Gum
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Benzyl Alcohol
1. Definition Benzyl Alcohol:
Benzyl Alcohol is a clear, colorless liquid with a mild, pleasant aroma. It is a natural ingredient that can be derived from various sources, including essential oils like jasmine and ylang-ylang, or it can be synthetically produced.2. Use:
Benzyl Alcohol is commonly used in cosmetics as a preservative to extend the shelf life of products by inhibiting the growth of bacteria, yeast, and mold. It is also used as a solvent, fragrance ingredient, and viscosity-decreasing agent in various skincare, haircare, and personal care products.3. Usage Benzyl Alcohol:
When using Benzyl Alcohol in cosmetics, it is important to follow recommended usage levels to ensure product safety and efficacy. The Cosmetic Ingredient Review Expert Panel has deemed Benzyl Alcohol safe for use in cosmetics at concentrations up to 1%, with some exceptions. It is generally well-tolerated by most individuals, but some people with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Benzyl Alcohol, especially if you have a history of skin sensitivities.4. References:
- Cosmetic Ingredient Review Expert Panel. (2008). Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. International Journal of Toxicology, 27(1), 1-23.
- Personal Care Products Council. (2019). Benzyl Alcohol. Retrieved from https://www.cosmeticsinfo.org/ingredient/benzyl-alcohol
- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 244, Benzyl Alcohol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-alcohol
Ammonium Hydroxide
1. Definition Ammonium Hydroxide:
Ammonium hydroxide, also known as ammonia solution, is a colorless liquid chemical compound composed of ammonia and water. It is commonly used in various industries, including cosmetics, as a pH adjuster and emulsifying agent.2. Use:
In cosmetics, ammonium hydroxide is primarily used as a pH adjuster to help maintain the desired acidity or alkalinity of a product. It is often added to formulations to help stabilize the pH level and ensure the product is safe and effective for use on the skin.3. Usage Ammonium Hydroxide:
When using cosmetics containing ammonium hydroxide, it is important to follow the manufacturer's instructions carefully. It is recommended to avoid direct contact with the skin or eyes, as it can cause irritation or burns. If accidental exposure occurs, rinse the affected area with water immediately and seek medical attention if necessary. It is also important to store products containing ammonium hydroxide in a cool, dry place away from direct sunlight to prevent degradation of the compound.4. References:
- "Ammonium Hydroxide." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/ammonium-hydroxide.
- "Ammonium Hydroxide." Personal Care Council, www.personalcarecouncil.org/ingredient-ammonium-hydroxide/.
- "Ammonium Hydroxide." Environmental Working Group, www.ewg.org/skindeep/ingredients/702159-AMMONIUM_HYDROXIDE/.
Arginine
1. Definition Arginine:
Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.2. Use:
In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.3. Usage Arginine:
Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.4. References:
- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.
- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.
- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.
Benzoic Acid
1. Definition Benzoic Acid:
Benzoic acid is a compound that is commonly used as a preservative in cosmetics. It is a white, crystalline powder with a faint, pleasant odor.2. Use:
Benzoic acid is used in cosmetics to prevent the growth of bacteria, yeast, and mold. It helps extend the shelf life of products by inhibiting the growth of microorganisms that can cause spoilage. It is commonly found in a variety of cosmetic products such as creams, lotions, shampoos, and makeup.3. Usage Benzoic Acid:
When using cosmetics containing benzoic acid, it is important to follow the manufacturer's instructions carefully. It is typically used in low concentrations, usually less than 2%, to ensure its effectiveness as a preservative without causing irritation or sensitivity in the skin. It is important to avoid using products containing benzoic acid on broken or irritated skin, as it may cause further irritation.Precautions: While benzoic acid is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing benzoic acid to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate." Int J Toxicol. 2001;20 Suppl 3:23-50.
- "Benzoic Acid." CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/benzoic-acid.
- "Benzoic Acid." PubChem, National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/Benzoic-acid.
Sorbic Acid
1. Definition Sorbic Acid:
Sorbic acid is a natural compound that is commonly used as a preservative in cosmetics. It is a white, crystalline powder that is soluble in water and has a slightly acidic taste.2. Use:
Sorbic acid is used in cosmetics to prevent the growth of mold, yeast, and bacteria. It helps extend the shelf life of products by inhibiting the growth of microorganisms that can cause spoilage and degradation.3. Usage Sorbic Acid:
Sorbic acid is typically used in concentrations of 0.2% to 1% in cosmetic formulations. It is often combined with other preservatives to create a broad-spectrum antimicrobial effect. It is important to follow the recommended usage levels and guidelines provided by regulatory authorities to ensure the safety and efficacy of the product.Precautions: While sorbic acid is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing sorbic acid, especially if you have sensitive skin. Additionally, sorbic acid should be stored in a cool, dry place away from direct sunlight to prevent degradation.
4. References:
- Cosmetics Info. (n.d.). Sorbic Acid. https://cosmeticsinfo.org/ingredient/sorbic-acid
- Personal Care Council. (2019). Sorbic Acid. https://www.personalcarecouncil.org/ingredient/sorbic-acid/
- U.S. Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.185
Titanium Dioxide
1. Definition Titanium Dioxide:
Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.2. Use:
Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.3. Usage Titanium Dioxide:
When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.4. References:
- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.
- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.
- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.
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