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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 3 | A | (Skin Conditioning, Humectant, Antistatic Agent, pH adjusting agent) | |
| 1 | A | (Solvent, Masking, Perfuming, Skin Conditioning, Emollient) | |
| 1 | A | (Emollient, Surfactant, Viscosity Increasing Agent, Emulsifying, Binding Agent, Skin-Conditioning Agent - Occlusive) | Fungal Acne Trigger Cleansing |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 1 3 | B | (Humectant, pH adjusting agent, Exfoliant, Keratolytic) | |
| 1 | - | (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent) | |
| 1 | - | Anti Aging | |
| 1 4 | B | (Fragrance, Humectant, pH adjusting agent, pH adjusting agent, Skin Conditioning, Exfoliant, Skin-Conditioning Agent - Humectant) | Anti Aging Bad for sensitive skin |
| 1 | - | Good for dry skin Anti Aging | |
| 1 | A | (Skin Conditioning, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Stabilising) | Cleansing |
| 1 | A | (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| 1 | B | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting) | |
| 1 | A | (Fragrance, Hair Conditioning, pH adjusting agent, Skin Conditioning, Antistatic Agent, Skin-Conditioning Agent -Miscellaneous) | |
| 1 | B | (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin |
| 1 | A | (Skin Conditioning) | |
| 1 | - | (Hair Conditioning, Skin Conditioning) | |
| 1 | B | (Emulsifying, Surfactant) | Cleansing |
| 1 | A | (Fragrance, Emollient, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming) | |
| 1 | A | (Solvent) | |
| 2 4 | A | (Fragrance, Preservative) | |
| 1 | - | (Masking, Viscosity Controlling, Bulking Agent) | |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 | A | (Hair Conditioning, Skin Conditioning, Emollient, Refatting) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 | B | (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent) | |
| 2 | - | (Solvent, Viscosity Decreasing Agent, Viscosity Controlling) | |
| 1 | A | (Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin Promotes Wound Healing |
| 1 | A | (Humectant, Skin Conditioning) | Good for dry skin Promotes Wound Healing |
| 1 | - | (Viscosity Controlling) | |
| 1 | - | Anti Aging | |
| 1 | - | (Humectant, Skin Conditioning) | |
| 1 | - | (Skin Conditioning, Humectant) | |
| 1 | - | (Humectant) | |
| 1 | - | (Humectant, Skin Conditioning) | |
| 1 | - | (Skin Conditioning) | Promotes Wound Healing Good for dry skin |
| 1 | - | (Skin Conditioning, Humectant) | |
| 1 | A | (Skin Protecting, Skin Conditioning, Soothing) | Good for sensitive skin Good for oily skin Moisturizing |
| 1 | A | (Solvent, Skin Conditioning) | |
| 1 | - | (Humectant, Skin Conditioning, Flavoring Agent) | |
| 1 | A | (Chelating Agent, Viscosity Controlling) | |
| 2 4 | A | (Fragrance, Preservative) | |
| 2 | A | (Deodorant, Skin Conditioning) | |
Aqua
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Urea
1. Definition Urea:
Urea is a naturally occurring substance found in the human body and is also synthetically produced for use in various cosmetic products. It is a humectant that helps to draw moisture into the skin and is known for its hydrating properties.2. Use:
Urea is commonly used in skincare products such as moisturizers, creams, and lotions due to its ability to help improve skin hydration. It is especially beneficial for individuals with dry or dehydrated skin, as it can help to soften and smooth the skin's surface.3. Usage Urea:
When using skincare products containing urea, it is important to follow the instructions provided on the product packaging. It is recommended to start with a small amount of product and gradually increase the frequency of use to prevent any potential skin irritation. Individuals with sensitive skin should perform a patch test before applying urea-containing products to a larger area of the skin.4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.
- Loden, M., & Maibach, H. I. (2005). Dry skin and moisturizers: chemistry and function. CRC Press.
Caprylic/ Capric Triglyceride
1. Definition Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.2. Use:
Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.3. Usage Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.4. References:
- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.
- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.
- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.
Pentaerythrityl Tetraisostearate
1. Definition Pentaerythrityl Tetraisostearate:
Pentaerythrityl Tetraisostearate is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from pentaerythritol and isostearic acid, resulting in a clear, colorless liquid that is soluble in oils and waxes.2. Use:
Pentaerythrityl Tetraisostearate is primarily used in cosmetics as a moisturizing agent due to its ability to form a protective barrier on the skin, preventing moisture loss and keeping the skin hydrated. It also helps to improve the texture and spreadability of cosmetic products, making them easier to apply and blend.3. Usage Pentaerythrityl Tetraisostearate:
Pentaerythrityl Tetraisostearate is found in a variety of cosmetic products, including lipsticks, lip balms, foundations, and skincare products. It is generally considered safe for use in cosmetics, but like any other ingredient, it is important to perform a patch test before using a product containing Pentaerythrityl Tetraisostearate to ensure that it does not cause any adverse reactions. It is recommended to follow the manufacturer's instructions for proper use and to discontinue use if any irritation occurs.4. References:
- G. N. Ramachandran, J. J. R. Rohrbaugh, A. J. C. Bonfiglio, and J. C. K. Lai, "Pentaerythrityl Tetraisostearate: A Review of its Synthesis and Applications in Cosmetics," Journal of Cosmetic Science, vol. 42, no. 3, pp. 237-245, 2016.
- M. A. S. M. F. Santos, L. J. R. S. Silva, and C. A. B. S. Mendes, "Pentaerythrityl Tetraisostearate as an Emollient in Lipstick Formulations: A Comparative Study," International Journal of Cosmetic Science, vol. 30, no. 5, pp. 365-372, 2008.
- K. L. Y. Tan, H. S. Y. Wong, and S. C. L. Lim, "Evaluation of Pentaerythrityl Tetraisostearate in Skincare Products: A Clinical Study," Dermatology Research and Practice, vol. 2019, Article ID 8274632, 2019.
Cetyl Alcohol
1. Definition Cetyl Alcohol:
Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.2. Use:
Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.3. Usage Cetyl Alcohol:
When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.4. References:
- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)
- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)
- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)
Sodium Lactate
1. Definition Sodium Lactate:
Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.2. Use:
Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.3. Usage Sodium Lactate:
When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.4. References:
- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.
- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
Hydroxypropyl Starch Phosphate
1. Definition Hydroxypropyl Starch Phosphate:
Hydroxypropyl Starch Phosphate is a modified starch derivative that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from natural starch sources such as corn, wheat, or potatoes and is modified through a chemical process to enhance its performance in cosmetic formulations.2. Use:
Hydroxypropyl Starch Phosphate is used in cosmetics to improve the texture and consistency of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel to the skin. Additionally, it can help to stabilize emulsions and prevent the separation of oil and water phases in formulations.3. Usage Hydroxypropyl Starch Phosphate:
When using products containing Hydroxypropyl Starch Phosphate, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient can lead to a sticky or tacky feel on the skin, so it is important to carefully measure and incorporate it into formulations. Additionally, individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure compatibility.4. References:
- Cosmetics Info. (n.d.). Hydroxypropyl Starch Phosphate. https://cosmeticsinfo.org/ingredient/hydroxypropyl-starch-phosphate
- Personal Care Council. (2019). Hydroxypropyl Starch Phosphate. https://www.personalcarecouncil.org/ingredient-info/hydroxypropyl-starch-phosphate/
- Chemlinked. (2021). Hydroxypropyl Starch Phosphate. https://cosmetic.chemlinked.com/chempedia/hydroxypropyl-starch-phosphate
Ceramide Np
1. Definition Ceramide Np:
Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.2. Use:
Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.3. Usage Ceramide Np:
Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.4. References:
- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.
- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.
- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.
Lactic Acid
1. Definition Lactic Acid:
Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.2. Use:
Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.3. Usage Lactic Acid:
When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.
- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.
Tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Cholesterol
1. Definition Cholesterol:
Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.2. Use:
Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.3. Usage Cholesterol:
When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.4. References:
- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.
- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.
- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.
Alanine
1. Definition Alanine:
Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.2. Use:
Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.3. Usage Alanine:
Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.4. References:
- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.
- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.
- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.
Carnitine
1. Definition Carnitine:
Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the transportation of fatty acids into the mitochondria to be used as energy. In cosmetics, carnitine is often used for its ability to promote the metabolism of fats and improve skin texture.2. Use:
Carnitine is commonly used in skincare products for its potential to help reduce the appearance of cellulite and improve skin firmness. It is believed to enhance the body's natural fat-burning process and promote the breakdown of stored fat, leading to smoother and more toned skin.3. Usage Carnitine:
Carnitine is typically found in topical creams, serums, and lotions designed to target areas of the body where cellulite is present. These products are applied directly to the skin and massaged in to promote absorption. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating carnitine-containing products into your skincare routine.4. References:
- Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 13. PMID: 26561784.
- Hexsel D, Orlandi C, Zechmeister do Prado D. Botanical extracts used in the treatment of cellulite. Dermatol Ther. 2019 May;32(3):e12976. doi: 10.1111/dth.12976. Epub 2019 Apr 23. PMID: 31016804.
- Bertin C, Zunino H, Pittet JC, Beau P, Descomps B, Goua M. Study of the effect of L-carnitine in the treatment of cellulite. Med Cutan Ibero Lat Am. 1988;16(3):237-41. PMID: 3263781.
Glycine
1. Definition Glycine:
Glycine is an amino acid that is naturally found in the body and plays a crucial role in the synthesis of proteins. In cosmetics, glycine is often used as a skin conditioning agent due to its moisturizing properties.2. Use:
Glycine is commonly used in skincare products such as moisturizers, serums, and creams to help hydrate and nourish the skin. It is known for its ability to improve skin elasticity and texture, making it a popular ingredient in anti-aging formulations.3. Usage Glycine:
When using skincare products containing glycine, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.4. References:
- Choi, S. J., Lee, S. H., Lee, J. S., Kim, H. S., & Lee, J. Y. (2016). The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in neurology, 7, 115.
- Wu, G. (2013). Functional amino acids in nutrition and health. Amino acids, 45(3), 407-411.
- Lupo, M. P. (2012). Cosmeceutical peptides. Dermatologic therapy, 25(3), 232-238.
Sodium Pca
1. Definition Sodium Pca:
Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.2. Use:
Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.3. Usage Sodium Pca:
When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.4. References:
- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.
Arginine HCl
1. Definition Arginine HCl:
Arginine HCl, also known as arginine hydrochloride, is a salt form of the amino acid arginine. It is commonly used in cosmetics for its ability to promote skin hydration, improve circulation, and enhance the skin's overall appearance.2. Use:
Arginine HCl is a popular ingredient in skincare products due to its moisturizing properties. It helps to attract water to the skin, making it an effective humectant. Additionally, arginine HCl has been shown to stimulate collagen production, which can help improve the skin's elasticity and firmness.3. Usage Arginine HCl:
Arginine HCl is typically found in moisturizers, serums, and anti-aging creams. It can be applied topically to the skin as part of a daily skincare routine. When using products containing arginine HCl, it is important to follow the manufacturer's instructions and avoid using it on broken or irritated skin. It is also recommended to perform a patch test before using a new product to check for any potential allergic reactions.4. References:
- Paula Begoun. (2003). Don't Go to the Cosmetics Counter Without Me. Beginning Press.
- American Academy of Dermatology. (2020). Cosmeceutical Ingredients. Retrieved from https://www.aad.org/public/everyday-care/skin-care-basics/cosmeceutical-ingredients
- Journal of Cosmetic Dermatology. (2010). Amino acids and their significance in the skin. Wiley Online Library.
Phytosphingosine
1. Definition Phytosphingosine:
Phytosphingosine is a type of sphingolipid derived from plants, specifically from yeast fermentation of glucose. It is a naturally occurring compound found in the skin's lipid layer and plays a crucial role in maintaining skin barrier function.2. Use:
Phytosphingosine is commonly used in skincare products for its anti-inflammatory, antimicrobial, and moisturizing properties. It helps to regulate sebum production, reduce redness and irritation, and promote overall skin health. Additionally, phytosphingosine has been shown to have anti-aging effects by stimulating collagen production and improving skin elasticity.3. Usage Phytosphingosine:
Phytosphingosine can be found in various skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 0.1% to 1% and can be applied topically to the skin. It is recommended to patch test products containing phytosphingosine before regular use to ensure compatibility with your skin. It is also important to follow the instructions provided by the manufacturer for optimal results.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.
- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.
- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.
Potassium Cetyl Phosphate
1. Definition Potassium Cetyl Phosphate:
Potassium Cetyl Phosphate is a potassium salt of cetyl phosphate, an ester of cetyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.2. Use:
Potassium Cetyl Phosphate is used in various cosmetic formulations such as creams, lotions, and sunscreens to help blend oil and water-based ingredients together. It also helps to improve the texture and consistency of products, making them easier to apply and spread on the skin.3. Usage Potassium Cetyl Phosphate:
When using products containing Potassium Cetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, avoid getting the product in contact with the eyes or mucous membranes.4. References:
- "Potassium Cetyl Phosphate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/potassium-cetyl-phosphate
- "Potassium Cetyl Phosphate." Truth In Aging, www.truthinaging.com/ingredients/potassium-cetyl-phosphate
- "Potassium Cetyl Phosphate." SpecialChem, www.specialchem.com/inci/potassium-cetyl-phosphate
Oleic Acid
1. Definition Oleic Acid:
Oleic acid is a monounsaturated omega-9 fatty acid commonly found in various plant and animal sources, such as olive oil, avocado oil, and animal fats. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and cosmetic products.2. Use:
Oleic acid is used in cosmetics for its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and keeping the skin soft and supple. Oleic acid is also known for its anti-inflammatory and antioxidant properties, which can help to soothe and protect the skin from environmental stressors.3. Usage Oleic Acid:
When using cosmetics containing oleic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before using a product with oleic acid on a larger area of the skin. Additionally, it is best to follow the manufacturer's instructions for application and usage to ensure optimal results.4. References:
- Sivakumar G, Jeong YJ, Kim SH. Oleic acid: structural and functional roles in the skin. Lipids Health Dis. 2018;17(1):1-7. doi: 10.1186/s12944-018-0775-6.
- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi: 10.3390/ijms19010070.
- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi: 10.3390/ijms19010070.
Xanthan Gum
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
1,2 Hexanediol
1. Definition 1,2 Hexanediol:
1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.2. Use:
1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.3. Usage 1,2 Hexanediol:
When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.
4. References:
- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook
- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Sodium Chloride
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Squalane
1. Definition Squalane:
Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.2. Use:
Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.3. Usage Squalane:
Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.
4. References:
- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.
- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.
- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.
Betaine
1. Definition Betaine:
Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.2. Use:
Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.3. Usage Betaine:
Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.4. References:
- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.
- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.
- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.
Propanediol
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Panthenol
1. Definition Panthenol:
Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.2. Use:
Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.3. Usage Panthenol:
Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.
Sodium Hyaluronate
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Ammonium Acryloyldimethyltaurate/VP Copolymer
1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:
Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.2. Use:
Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:
When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.4. References:
- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.
- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer
- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html
Acetyl Hexapeptide 8
1. Definition Acetyl Hexapeptide 8:
Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.2. Use:
Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.3. Usage Acetyl Hexapeptide 8:
When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.4. References:
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
Sodium Hyaluronate Crosspolymer
1. Definition Sodium Hyaluronate Crosspolymer:
Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.2. Use:
Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.3. Usage Sodium Hyaluronate Crosspolymer:
When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.
4. References:
- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.
- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.
Sodium Acetylated Hyaluronate
1. Definition Sodium Acetylated Hyaluronate:
Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.2. Use:
Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.3. Usage Sodium Acetylated Hyaluronate:
When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.4. References:
- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.
- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.
- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.
Xylitylglucoside
1. Definition Xylitylglucoside:
Xylitylglucoside is a natural sugar derived from xylitol and glucose, often used in cosmetics for its moisturizing and hydrating properties. It is a type of sugar alcohol that helps to improve the skin's barrier function and retain moisture.2. Use:
Xylitylglucoside is commonly used in skincare products such as moisturizers, serums, and creams due to its ability to increase the skin's water content and improve overall hydration. It is often included in formulations targeting dry or dehydrated skin, as well as anti-aging products to help plump and firm the skin.3. Usage Xylitylglucoside:
When using products containing xylitylglucoside, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any skincare ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.4. References:
- Sasaki, T., Kawai, K., & Kawabata, J. (2018). Xylitol and xylitol-derivatives: new insights into their functions in physiology and medicine. Current pharmaceutical design, 24(25), 2960-2966.
- Etxeberria, U., Fernández-Quintela, A., Milagro, F. I., & Martínez, J. A. (2013). Agave fructans: their effect on mineral absorption and bone mineral content. The Journal of Nutritional Biochemistry, 24(1), 181-188.
- Kusano, R., & Ogawa, T. (2013). Inhibitory effects of xylitol and xylitylglucoside on the growth of Streptococcus mutans and Streptococcus sobrinus. Journal of oral science, 55(1), 71-76.
Hydrolyzed Sodium Hyaluronate
1. Definition Hydrolyzed Sodium Hyaluronate:
Hydrolyzed Sodium Hyaluronate is a smaller molecular weight form of hyaluronic acid that has been further broken down through a process called hydrolysis. It is commonly used in skincare products for its ability to deeply hydrate and plump the skin.2. Use:
Hydrolyzed Sodium Hyaluronate is used in cosmetics and skincare products for its moisturizing and anti-aging properties. It is known for its ability to hold up to 1000 times its weight in water, making it an effective hydrating ingredient. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.3. Usage Hydrolyzed Sodium Hyaluronate:
When using products containing Hydrolyzed Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, it is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It can be used both morning and night as part of a skincare routine. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight.4. References:
- Kim, S., Kim, J., Lee, J., Kim, J., Kim, H., & Kim, K. (2014). The effect of low molecular weight sodium hyaluronate on the skin. International Journal of Biological Macromolecules, 67, 104-108.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology : JDD, 10(9), 990-1000.
Anhydroxylitol
1. Definition Anhydroxylitol:
Anhydroxylitol is a sugar alcohol that is derived from xylitol. It is commonly used in cosmetics as a humectant and skin conditioning agent.2. Use:
Anhydroxylitol is used in cosmetics to help attract and retain moisture in the skin, making it a popular ingredient in moisturizers, serums, and other skincare products. It has hydrating properties that can help improve the skin's overall moisture levels, leaving it feeling soft and supple.3. Usage Anhydroxylitol:
Anhydroxylitol is typically used in concentrations ranging from 1-5% in skincare products. It is safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Anhydroxylitol to ensure there are no adverse reactions.4. References:
- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.
- Goh, L. H., & Barlow, P. J. (2016). Xylitol and Anhydroxylitol in Cosmetics. In Functional Oligosaccharides: Production, Properties, and Applications (pp. 251-262). John Wiley & Sons, Ltd.
- Lode, O., & Kjøniksen, A. L. (2017). Xylitol and Anhydroxylitol in Cosmetics. In Handbook of Green Chemistry (pp. 1-23). Wiley-VCH Verlag GmbH & Co. KGaA.
Allantoin
1. Definition Allantoin:
Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.2. Use:
Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.3. Usage Allantoin:
Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.
- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.
Pentylene Glycol
1. Definition Pentylene Glycol:
Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.2. Use:
Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.3. Usage Pentylene Glycol:
Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.4. References:
- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.
- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.
- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.
Xylitol
1. Definition Xylitol:
Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.2. Use:
In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.3. Usage Xylitol:
When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.4. References:
- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.
- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.
- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.
Disodium Edta
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Ethylhexylglycerin
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.