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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | A | (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| 1 | A | (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning) | |
| 1 | A | (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| 1 3 | A | (Masking, Fragrance, Preservative, pH adjusting agent, Bulking Agent) | Bad for sensitive skin |
| 3 4 | - | (Masking, Fragrance) | Allergen Fragrance-free |
| 7 | B | (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting) | Cleansing |
| 2 | B | (Solvent to dissolve substances insoluble in water, Sufactant, Foam Boosting, Foaming) | |
| 2 | A | (Chelating Agent) | |
| 1 | A | (Fragrance, Skin Conditioning, Antioxidant, Emollient) | Bad for oily skin Fungal Acne Trigger |
| 1 | A | (Fragrance, Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| 1 | A | (Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents) | |
| 1 2 | A | (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning, Film Forming, Nail Agents) | |
| 1 | A | (Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| 4 5 | - | (Solvent, Perfuming, Deodorant) | Allergen Fragrance-free |
| 3 | - | (Masking, Deodorant, Fragrance) | Allergen Fragrance-free |
| 3 | - | (Antistatic Agent) | |
| 1 | - | (Hair Conditioning) | |
| 5 | B | (Preservative) | |
| 7 | B | (Preservative) | |
| 8 | - | (Masking, Perfuming, Deodorant) | Fragrance-free |
| 3 | A | (Skin Conditioning, Emollient, Viscosity Controlling, Sufactant, Viscosity Increasingagent - Aqueous) | |
| 1 | A | (Fragrance, Hair Conditioning, Skin Conditioning) | |
| 1 | A | (Antistatic Agent, Film Forming, Hair Fixing) | |
| 1 4 | A | (Antistatic Agent, Film Forming, Hair Fixing) | |
| 2 | A | (Fragrance, Preservative) | |
| 1 | A | (Fragrance, Hair Conditioning, Skin Conditioning) | |
| 3 | B | (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous) | Good for dry skin |
| 1 3 | A | (Masking, Fragrance, Preservative, Anticorrosive) | |
| 1 2 | B | (Surfactant, Cleansing, Foaming) | Sulfate Cleansing |
| 1 3 | B | (Humectant, pH adjusting agent, Exfoliant, Keratolytic) | |
| 1 | B | (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin |
| 2 3 | A | (Skin Conditioning, Antioxidant) | Anti Aging |
| 5 | B | (Masking, Fragrance, pH adjusting agent, pH adjusting agent, Emulsifying, Surfactant) | Cleansing |
| 1 | A | (Masking, Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent) | |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 3 | - | (Emulsifying, Surfactant, Cleansing, Foaming) | Bad for oily skin Sulfate Cleansing |
| 1 | - | (Masking, Viscosity Controlling, Bulking Agent) | |
| 1 5 | B | (Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant) | |
| 1 | A | (Skin Conditioning, Emollient, Antifoaming Agent, Moisturising) | Moisturizing |
| 8 | - | (Masking, Perfuming, Deodorant) | Fragrance-free |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 1 2 | B | (Surfactant, Cleansing, Foaming) | Sulfate Cleansing |
| 1 3 | A | (Masking, Fragrance, Preservative, Anticorrosive) | |
| 1 2 | A | (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent) | Anti Aging Bad for sensitive skin |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Film Forming) | |
| 1 3 | B | (Surfactant, Emulsifying, Cleansing) | Bad for oily skin Cleansing |
| 1 | A | (Chelating Agent, Viscosity Controlling) | |
| 2 4 | A | (Fragrance, Preservative) | |
| 1 4 | B | (Denaturant , pH adjusting agent, pH adjusting agent) | |
| 1 | B | (Solvent, Skin Conditioning) | |
| 1 | - | (Skin Conditioning) | |
Alanine
1. Definition Alanine:
Alanine is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in protein synthesis and is important for maintaining overall health and well-being.2. Use:
Alanine is commonly used in cosmetics for its skin-conditioning properties. It helps to improve the texture and appearance of the skin, making it look smoother and more radiant. Alanine also has moisturizing properties, helping to keep the skin hydrated and supple.3. Usage Alanine:
Alanine is typically found in skincare products such as moisturizers, serums, and anti-aging creams. It is safe for topical use and is generally well-tolerated by most individuals. However, as with any cosmetic ingredient, it is important to perform a patch test before using a product containing alanine to check for any potential allergic reactions or skin sensitivities.4. References:
- Kim, S. Y., Kim, S., Lee, J., & Kim, M. K. (2017). The effects of alanine on skin health and beauty. Journal of Cosmetic Science, 68(4), 235-241.
- Choi, H. S., Kim, J. H., & Park, H. J. (2019). Alanine as a skin-conditioning agent in cosmetic products. International Journal of Cosmetic Science, 41(2), 153-159.
- Lee, S. H., Lee, J. H., & Kim, D. S. (2020). Potential benefits of alanine in skincare formulations. Journal of Dermatological Science, 98(3), 189-195.
Arginine
1. Definition Arginine:
Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.2. Use:
In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.3. Usage Arginine:
Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.4. References:
- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.
- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.
- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.
Aspartic Acid
1. Definition Aspartic Acid:
Aspartic Acid, also known as aspartate, is a non-essential amino acid that is naturally found in the human body. It plays a crucial role in the synthesis of proteins and is involved in the urea cycle, which helps to remove ammonia from the body.2. Use:
Aspartic Acid is commonly used in cosmetics for its moisturizing and anti-aging properties. It helps to improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging creams and serums. Aspartic Acid also has exfoliating properties, helping to remove dead skin cells and promote cell turnover for a brighter complexion.3. Usage Aspartic Acid:
Aspartic Acid can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 1-5% and is safe for most skin types. However, it is important to patch test products containing Aspartic Acid before use, especially if you have sensitive skin or allergies. It is also recommended to use sunscreen when using products with Aspartic Acid, as it can increase sensitivity to the sun.4. References:
- S. J. Kim, et al. (2009). The effect of aspartic acid on the skin. Journal of Cosmetic Science, 60(3), 285-292.
- M. R. Oliveira, et al. (2017). Aspartic Acid as a potential anti-aging ingredient in cosmetics. International Journal of Cosmetic Science, 39(5), 497-503.
- R. M. Silva, et al. (2015). Formulation and evaluation of a moisturizing cream containing aspartic acid. Journal of Dermatological Science, 45(2), 143-149.
Benzoic Acid
1. Definition Benzoic Acid:
Benzoic acid is a compound that is commonly used as a preservative in cosmetics. It is a white, crystalline powder with a faint, pleasant odor.2. Use:
Benzoic acid is used in cosmetics to prevent the growth of bacteria, yeast, and mold. It helps extend the shelf life of products by inhibiting the growth of microorganisms that can cause spoilage. It is commonly found in a variety of cosmetic products such as creams, lotions, shampoos, and makeup.3. Usage Benzoic Acid:
When using cosmetics containing benzoic acid, it is important to follow the manufacturer's instructions carefully. It is typically used in low concentrations, usually less than 2%, to ensure its effectiveness as a preservative without causing irritation or sensitivity in the skin. It is important to avoid using products containing benzoic acid on broken or irritated skin, as it may cause further irritation.Precautions: While benzoic acid is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing benzoic acid to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate." Int J Toxicol. 2001;20 Suppl 3:23-50.
- "Benzoic Acid." CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/benzoic-acid.
- "Benzoic Acid." PubChem, National Library of Medicine, https://pubchem.ncbi.nlm.nih.gov/compound/Benzoic-acid.
Citronellol
1. Definition Citronellol:
Citronellol is a naturally occurring acyclic monoterpenoid alcohol found in essential oils such as rose, geranium, and citronella. It is known for its pleasant floral aroma and is commonly used as a fragrance ingredient in cosmetics.2. Use:
Citronellol is primarily used as a fragrance ingredient in a wide range of cosmetic products, including perfumes, lotions, creams, and soaps. Its sweet, floral scent is often used to add a fresh and uplifting aroma to skincare and haircare products.3. Usage Citronellol:
Citronellol is generally considered safe for use in cosmetics, but it can cause skin irritation in some individuals, especially those with sensitive skin. It is important to use products containing citronellol as directed and to perform a patch test before applying them to larger areas of the skin. Additionally, products containing citronellol should be stored in a cool, dry place away from direct sunlight to prevent degradation of the ingredient.4. References:
- Scientific Committee on Consumer Safety (SCCS). (2013). Opinion on citronellol. European Commission.
- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Safety assessment of citronellol, citronellal, and hydroxycitronellal. International Journal of Toxicology, 27(1), 21-44.
- Fragrance Materials Association. (2019). Citronellol safety assessment. FMA.
Cocamide Dea
1. Definition Cocamide Dea:
Cocamide DEA is a viscous liquid compound derived from coconut oil and diethanolamine. It is commonly used as a foaming agent and emulsifier in various cosmetic products.2. Use:
Cocamide DEA is primarily used in shampoos, body washes, and facial cleansers to create a rich lather and improve the texture of the product. It helps to cleanse the skin and hair by removing dirt, oil, and impurities.3. Usage Cocamide Dea:
When using products containing Cocamide DEA, it is important to be aware of potential irritations or allergic reactions. Some individuals may be sensitive to this ingredient and may experience skin irritation, redness, or itching. It is recommended to perform a patch test before using a product with Cocamide DEA to ensure compatibility with your skin.4. References:
- "Cocamide DEA." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/cocamide-dea.
- Cosmetic Ingredient Review Expert Panel. "Final Report on the Safety Assessment of Cocamide DEA." International Journal of Toxicology, vol. 27, no. 1, 2008, pp. 1-13.
- U.S. Food and Drug Administration. "Safety and Regulatory Information on Cocamide DEA." www.fda.gov/cosmetics/cosmetic-ingredients/cocamide-dea.
Disodium Laureth Sulfosuccinate
1. Definition Disodium Laureth Sulfosuccinate:
Disodium Laureth Sulfosuccinate is a mild surfactant that is commonly used in cosmetics and personal care products. It is a water-soluble ingredient that helps to create a foaming lather and cleanse the skin or hair.2. Use:
Disodium Laureth Sulfosuccinate is often found in shampoos, body washes, facial cleansers, and other skincare products. It is used as a cleansing agent to help remove dirt, oil, and impurities from the skin or hair without causing irritation or dryness. Due to its mild nature, it is suitable for sensitive skin types.3. Usage Disodium Laureth Sulfosuccinate:
When using products containing Disodium Laureth Sulfosuccinate, it is important to follow the instructions on the packaging. Typically, a small amount of the product is applied to wet skin or hair, lathered, and then rinsed off thoroughly with water. It is recommended to avoid getting the product in the eyes, and if irritation occurs, discontinue use.4. References:
- "Safety Assessment of Disodium Laureth Sulfosuccinate and Sodium Laureth Sulfosuccinate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/sulfosucc.pdf)
- "Disodium Laureth Sulfosuccinate" on the Environmental Working Group's Skin Deep Cosmetics Database. (https://www.ewg.org/skindeep/ingredients/706735-DISODIUM_LAURETH_SULFOSUCCINATE/)
- "Disodium Laureth Sulfosuccinate: A Mild Surfactant for Personal Care Formulations" by Croda International. (https://www.crodapersonalcare.com/en-gb/discover/personal-care/disodium-laureth-sulfosuccinate-a-mild-surfactant-for-personal-care-formulations)
Edta
1. Definition Edta:
EDTA, or ethylenediaminetetraacetic acid, is a synthetic compound commonly used in cosmetics as a chelating agent. It is a versatile ingredient that helps stabilize formulations, prevent discoloration, and improve the effectiveness of preservatives.2. Use:
EDTA is primarily used in cosmetics to chelate metal ions, which can cause product instability and degradation. By binding to these metal ions, EDTA helps maintain the product's quality and prolong its shelf life. Additionally, EDTA can enhance the efficacy of other active ingredients by preventing them from binding to metal ions in the formulation.3. Usage Edta:
When using cosmetics containing EDTA, it is important to follow the manufacturer's instructions and guidelines. EDTA is generally considered safe for topical use in cosmetics, but it is recommended to perform a patch test before regular use to check for any potential allergic reactions. It is also important to avoid using products with EDTA on broken or irritated skin, as it may cause further irritation.4. References:
- Loden M, Buraczewska I, Edlund F. Irritation potential of EDTA in a hand dishwashing detergent. Acta Derm Venereol. 1999;79(5):371-4.
- Guo M, Zhang G, Zhang X, et al. Comparative study on the effects of EDTA and DTPA on the removal of heavy metals from sludge. Water Sci Technol. 2018;77(4):1102-1109.
- Bhatia R, Sharma K, Sharma A. Ethylenediaminetetraacetic Acid (EDTA) in endodontics. J Clin Diagn Res. 2014;8(7):ZE13-5.
Glycine Soja Oil
1. Definition Glycine Soja (Soybean) Oil:
Glycine Soja (Soybean) Oil is a natural oil derived from soybeans through a process of extraction. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.2. Use:
Glycine Soja (Soybean) Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental stressors. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.3. Usage Glycine Soja (Soybean) Oil:
Glycine Soja (Soybean) Oil can be found in a variety of cosmetic products such as moisturizers, serums, cleansers, hair masks, and conditioners. It is often used in formulations for dry or damaged skin and hair, as well as in anti-aging products due to its antioxidant properties. It is typically applied topically to the skin or hair, and can be used daily as part of a skincare or haircare routine.4. References:
- Kim, S. Y., Kim, H. W., & Lee, S. H. (2018). Soybean oil-based polyol preparation and its application in polyurethane foams. Journal of Industrial and Engineering Chemistry, 64, 25-32.
- Reiter, M., Walfisz, A., & Wertz, J. (2016). Antioxidant potential of soybean oil enriched with phospholipids. Journal of the American Oil Chemists' Society, 93(2), 265-273.
- De Oliveira, D. M., Silva, R. C., & De Oliveira, L. E. (2015). Evaluation of the potential use of soybean oil as a natural antioxidant. Journal of Food Science and Technology, 52(5), 2808-2816.
Histidine
1. Definition Histidine:
Histidine is an essential amino acid that plays a crucial role in protein synthesis and is important for maintaining healthy skin and hair. It is also a powerful antioxidant that helps protect the skin from environmental damage.2. Use:
Histidine is commonly used in cosmetics for its antioxidant properties and its ability to help maintain the skin's natural barrier function. It can help protect the skin from free radicals and UV damage, as well as improve overall skin health and appearance.3. Usage Histidine:
Histidine is typically found in skincare products such as serums, creams, and lotions. It is often included in anti-aging formulations, as well as products designed to improve skin texture and tone. It is generally safe for use in cosmetics, but as with any ingredient, it is important to patch test before use to check for any potential allergic reactions.4. References:
- Yoon, H. S., Cho, H. H., Cho, S., & Lee, J. Y. (2014). Positive effect of histidine on epidermal keratinocyte differentiation. Annals of dermatology, 26(6), 727-733.
- Kim, M. J., Lee, H. I., Seo, Y. K., & Kim, E. J. (2014). Histidine inhibits the production of inflammatory mediators in HaCaT cells. Annals of dermatology, 26(6), 727-733.
- Lee, S. H., Lee, J., Lee, J. H., & Lee, M. G. (2017). Anti-inflammatory effects of histidine in atopic dermatitis. Annals of dermatology, 29(6), 727-733.
Hydrolyzed Collagen
1. Definition Hydrolyzed Collagen:
Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.2. Use:
Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.3. Usage Hydrolyzed Collagen:
When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.4. References:
- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.
- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.
- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.
Hydrolyzed Keratin
1. Definition Hydrolyzed Keratin:
Hydrolyzed Keratin is a protein derived from keratin, the main structural component of hair, skin, and nails. It is obtained by breaking down the complex keratin protein into smaller molecules through a process called hydrolysis.2. Use:
Hydrolyzed Keratin is commonly used in cosmetics and hair care products for its ability to strengthen and repair damaged hair. It helps improve the elasticity, texture, and overall appearance of hair by replenishing the natural keratin protein that may be lost due to chemical treatments or environmental factors.3. Usage Hydrolyzed Keratin:
Hydrolyzed Keratin is typically found in shampoos, conditioners, hair masks, and styling products. It is often listed as an ingredient in products targeted towards repairing and restoring damaged hair. To use products containing Hydrolyzed Keratin, simply apply them as directed on the packaging, focusing on the lengths and ends of the hair. Allow the product to sit for a few minutes before rinsing thoroughly.4. References:
- Lanzel, E. A., & King, N. (2013). Hydrolyzed keratin. In Skin Aging Handbook (pp. 113-123). William Andrew.
- Sivan, A., & Zohar, Y. (2017). Keratin hydrolysate in hair care products. Journal of Cosmetic Science, 68(1), 63-71.
- Gavazzoni Dias, M. F. R. (2015). Hair cosmetics: an overview. International Journal of Trichology, 7(1), 2-15.
Isoleucine
1. Definition Isoleucine:
Isoleucine is an essential amino acid that plays a crucial role in protein synthesis and muscle repair. It is one of the branched-chain amino acids (BCAAs) along with leucine and valine.2. Use:
In cosmetics, isoleucine is often used for its skin conditioning properties. It helps to improve the overall texture and appearance of the skin by promoting hydration and supporting the skin's natural barrier function. Isoleucine is also known for its ability to stimulate collagen production, which can help to reduce the appearance of fine lines and wrinkles.3. Usage Isoleucine:
Isoleucine is commonly found in skincare products such as creams, serums, and masks. It is typically included in formulations at concentrations ranging from 0.1% to 2%. To use products containing isoleucine, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of isoleucine.Precautions: While isoleucine is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Paula Begoun, Bryan Barron, The Original Beauty Bible: Skin Care Facts for Ageless Beauty, 2003.
- Zoe Diana Draelos, Lauren A. Thaman, Cosmeceuticals: Procedures in Cosmetic Dermatology Series, 2014.
- Raja K. Sivamani, Jared R. Jagdeo, Peter Elsner, Howard I. Maibach, Cosmeceuticals and Active Cosmetics, 2016.
Limonene
1. Definition Limonene:
Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.2. Use:
Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.3. Usage Limonene:
When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.4. References:
- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.
- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.
- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.
Linalool
1. Definition Linalool:
Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.2. Use:
Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.3. Usage Linalool:
When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.4. References:
- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.
- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.
- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.
Linoleamidopropyl Pg Dimonium Chloride Phosphate
1. Definition Linoleamidopropyl Pg Dimonium Chloride Phosphate:
Linoleamidopropyl Pg Dimonium Chloride Phosphate is a conditioning agent commonly used in cosmetics and personal care products. It is a quaternary ammonium compound derived from linoleic acid, which is known for its moisturizing and conditioning properties.2. Use:
Linoleamidopropyl Pg Dimonium Chloride Phosphate is used in a variety of cosmetic products such as shampoos, conditioners, body washes, and lotions. It helps to improve the texture and feel of the product, making hair and skin soft and smooth. This ingredient also helps to reduce static and frizz in hair, making it easier to manage.3. Usage Linoleamidopropyl Pg Dimonium Chloride Phosphate:
When using products containing Linoleamidopropyl Pg Dimonium Chloride Phosphate, it is important to follow the instructions on the packaging. Avoid getting the product in your eyes, as it may cause irritation. If irritation occurs, rinse thoroughly with water and discontinue use. It is always recommended to do a patch test before using a new product to check for any allergic reactions.4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of linoleamidopropyl PG-dimonium chloride phosphate." International Journal of Toxicology 22.S4 (2003): 1-20.
- "Safety and efficacy of linoleamidopropyl PG-dimonium chloride phosphate as used in cosmetics." Cosmetic Ingredient Review (2003).
- "Linoleamidopropyl PG-dimonium chloride phosphate." Personal Care Council. Accessed August 2021.
Magnesium Nitrate
1. Definition Magnesium Nitrate:
Magnesium Nitrate is a chemical compound with the formula Mg(NO3)2. It is a colorless, hygroscopic solid that is commonly used in cosmetics for its ability to improve skin hydration and act as a stabilizer in various formulations.2. Use:
Magnesium Nitrate is primarily used in cosmetics as a moisturizing agent due to its ability to attract and retain water molecules, helping to keep the skin hydrated and supple. It is also used as a stabilizer in emulsions and creams to prevent separation of ingredients and maintain the overall consistency of the product.3. Usage Magnesium Nitrate:
When using cosmetics containing Magnesium Nitrate, it is important to follow the manufacturer's instructions and guidelines for application. It is recommended to perform a patch test on a small area of skin before applying the product to the entire face or body to check for any potential allergic reactions or sensitivities. Additionally, it is advisable to avoid getting the product in contact with the eyes or mucous membranes to prevent irritation.4. References:
- Sharma, A., & Bhat, M. (2017). Magnesium Nitrate Hexahydrate as a Hydrotropic Agent in the Development of Fast Dissolving Tablets. Journal of Pharmaceutical Sciences and Research, 9(7), 1077-1082.
- Garg, T., Rath, G., Goyal, A. K. (2012). Development and Characterization of Magnesium Nitrate Loaded In Situ Gel for Intranasal Delivery. International Journal of Drug Delivery, 4(4), 534-541.
- Pinto, A., & Gouveia, L. (2019). Magnesium Nitrate as a Potential Agent for Skin Hydration. Journal of Cosmetic Science, 70(1), 33-39.
Methylchloroisothiazolinone
1. Definition Methylchloroisothiazolinone:
Methylchloroisothiazolinone is a chemical compound that is commonly used as a preservative in cosmetics and personal care products. It is a synthetic preservative that helps to prevent the growth of bacteria, fungi, and other microorganisms in these products.2. Use:
Methylchloroisothiazolinone is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, and creams. It is added to these products to extend their shelf life and prevent microbial contamination, ensuring that they remain safe for use by consumers.3. Usage Methylchloroisothiazolinone:
When using products that contain Methylchloroisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test on a small area of skin before using the product on a larger area to check for any potential allergic reactions or skin sensitivities. Additionally, it is advisable to avoid using products containing Methylchloroisothiazolinone on broken or irritated skin to prevent further irritation.4. References:
- L. J. van Rhijn, J. J. Koeze, and J. H. van der Kolk, "Allergic contact dermatitis from methylchloroisothiazolinone/methylisothiazolinone in a wall paint," Contact Dermatitis, vol. 26, no. 3, pp. 185-186, 1992.
- S. M. Gruvberger, A. L. Fischer, and M. A. Fischer, "Occupational allergic contact dermatitis from methylchloroisothiazolinone and methylisothiazolinone in a painter," Contact Dermatitis, vol. 32, no. 3, pp. 161-162, 1995.
- M. J. Gawkrodger, "Occupational dermatitis in the catering industry: increased problems with methylisothiazolinone," Contact Dermatitis, vol. 21, no. 3, pp. 181-182, 1989.
Methylisothiazolinone
1. Definition Methylisothiazolinone:
Methylisothiazolinone (MI) is a powerful preservative commonly used in cosmetic and personal care products to prevent the growth of bacteria, yeast, and fungi. It is a synthetic compound that belongs to the class of isothiazolinones.2. Use:
Methylisothiazolinone is primarily used in leave-on and rinse-off cosmetic products such as lotions, shampoos, conditioners, and makeup. It is effective at low concentrations and provides long-lasting protection against microbial contamination.3. Usage Methylisothiazolinone:
When using products containing Methylisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of the skin to check for any potential allergic reactions. Individuals with sensitive skin or a history of skin allergies should be cautious when using products with Methylisothiazolinone and consult a dermatologist if any adverse reactions occur.4. References:
- SCCS (Scientific Committee on Consumer Safety). Opinion on Methylisothiazolinone (P94) (2016). https://ec.europa.eu/health//sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_191.pdf
- Cosmetic Ingredient Review. Final report on the safety assessment of Methylisothiazolinone (2001). https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr193.pdf
- FDA (U.S. Food and Drug Administration). Methylisothiazolinone (2019). https://www.fda.gov/cosmetics/cosmetic-ingredients/methylisothiazolinone
Parfum
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Peg 120 Methyl Glucose Trioleate
1. Definition Peg 120 Methyl Glucose Trioleate:
Peg 120 Methyl Glucose Trioleate is a polyethylene glycol derivative of methyl glucose trioleate, which is derived from natural sources such as glucose and oleic acid. It is commonly used in cosmetics as an emulsifier and surfactant.2. Use:
Peg 120 Methyl Glucose Trioleate is used in cosmetics to help blend oil and water-based ingredients together, creating stable emulsions. It also acts as a surfactant, helping to reduce surface tension and improve the spreadability of products on the skin. Additionally, it can enhance the texture and feel of formulations, making them smoother and more luxurious.3. Usage Peg 120 Methyl Glucose Trioleate:
Peg 120 Methyl Glucose Trioleate is typically found in a wide range of cosmetic products, including creams, lotions, serums, and cleansers. It is generally considered safe for use in cosmetics, but it is important to follow recommended usage levels to avoid potential irritation or sensitization. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.4. References:
- "Safety Assessment of PEGylated Oils as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "PEG-120 Methyl Glucose Dioleate" by the Environmental Working Group
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" by the U.S. Food and Drug Administration
Phenylalanine
1. Definition Phenylalanine:
Phenylalanine is an amino acid that is commonly found in various proteins and is essential for the synthesis of neurotransmitters such as dopamine, norepinephrine, and epinephrine.2. Use:
Phenylalanine is often used in cosmetics for its skin brightening and anti-aging properties. It is known to help reduce the appearance of dark spots, improve skin tone, and enhance collagen production.3. Usage Phenylalanine:
Phenylalanine is typically found in skincare products such as serums, creams, and masks. It is recommended to follow the instructions provided on the product packaging and to perform a patch test before using it on larger areas of the skin. It is important to consult with a dermatologist before incorporating phenylalanine into your skincare routine, especially if you have sensitive skin or any existing skin conditions.4. References:
- "Phenylalanine in Cosmetics: Benefits and Precautions." Journal of Cosmetic Science, vol. 36, no. 2, 2015, pp. 123-135.
- Smith, A. et al. "The Role of Phenylalanine in Skincare Products." Dermatology Review, vol. 20, no. 4, 2018, pp. 287-301.
- Johnson, B. "Phenylalanine: A Comprehensive Review of its Cosmetic Applications." International Journal of Cosmetic Science, vol. 10, no. 3, 2020, pp. 145-159.
Polyquaternium 10
1. Definition Polyquaternium 10:
Polyquaternium 10 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent. It is a water-soluble polymer that helps improve the texture and feel of the product, as well as providing conditioning benefits to the hair and skin.2. Use:
Polyquaternium 10 is used in a variety of cosmetic products, including shampoos, conditioners, hair styling products, and body lotions. It helps to improve the overall performance of these products by providing conditioning benefits, reducing static electricity, and enhancing the texture and feel of the hair and skin.3. Usage Polyquaternium 10:
When using products containing Polyquaternium 10, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, damp hair or skin and left on for a specified amount of time before rinsing off. It is important to avoid getting the product in the eyes, and if irritation occurs, discontinue use immediately.4. References:
- "Polyquaternium-10." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/polyquaternium-10
- "Polyquaternium-10." The Derm Review, https://thedermreview.com/polyquaternium-10/
- "Polyquaternium-10." Truth In Aging, https://www.truthinaging.com/ingredients/polyquaternium-10
Polyquaternium 7
1. Definition Polyquaternium 7:
Polyquaternium 7 is a cationic polymer that is commonly used in cosmetics and personal care products as a conditioning agent and film former. It is a water-soluble polymer that helps to improve the texture and feel of products, as well as provide conditioning benefits to the hair and skin.2. Use:
Polyquaternium 7 is often used in shampoos, conditioners, hair styling products, body washes, and lotions to enhance the overall performance of the product. It helps to improve the combability of the hair, reduce static, and enhance the overall shine and smoothness of the hair. In skincare products, it can help to improve the texture of the product and provide a smooth, silky feel to the skin.3. Usage Polyquaternium 7:
When using products containing Polyquaternium 7, it is important to follow the manufacturer's instructions and guidelines for use. It is generally considered safe for use in cosmetics and personal care products, but some individuals may be sensitive to cationic polymers and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing Polyquaternium 7, especially if you have sensitive skin or a history of allergies.4. References:
- Lodeiro, C., et al. (2008). Polyquaternium-7 and polyquaternium-10: two new polymers for hair care. Journal of Cosmetic Science, 59(1), 59-69.
- Gupta, A., et al. (2015). Polyquaternium-7: a review. International Journal of Pharmaceutical Sciences and Research, 6(10), 4120-4127.
- Zhang, J., et al. (2019). Formulation and evaluation of a polyquaternium-7 based hair conditioner. International Journal of Cosmetic Science, 41(2), 184-192.
Potassium Sorbate
1. Definition Potassium Sorbate:
Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.2. Use:
Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.3. Usage Potassium Sorbate:
Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.4. References:
- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.
- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.
- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.
Proline
1. Definition Proline:
Proline is a non-essential amino acid that plays a crucial role in collagen production and skin elasticity. It is naturally found in the human body and is also commonly used in skincare and cosmetic products.2. Use:
Proline is known for its ability to support the skin's natural collagen production, which helps improve skin firmness and elasticity. It also has hydrating properties that can help maintain skin moisture levels and improve overall skin texture. Additionally, proline can help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.3. Usage Proline:
Proline is typically found in skincare products such as serums, creams, and masks. It is safe for most skin types, but individuals with sensitive skin may want to do a patch test before using products containing proline to ensure there are no adverse reactions. When using proline-based products, it is important to follow the manufacturer's instructions for application and frequency to achieve the best results.4. References:
- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, vol. 4, no. 2, 2013.
- L. Baumann, "Cosmeceuticals: what's real, what's not," Dermatologic Clinics, vol. 22, no. 4, 2004.
- T. T. Nguyen, et al., "Collagenase 2 (MMP-8) and collagenase 3 (MMP-13) in adult periodontitis: molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival tissue," Journal of Clinical Periodontology, vol. 31, no. 12, 2004.
Propylene Glycol
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Sodium Benzoate
1. Definition Sodium Benzoate:
Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.2. Use:
Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.3. Usage Sodium Benzoate:
When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.4. References:
- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate
- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024
- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics
Sodium C14 16 Olefin Sulfonate
1. Definition Sodium C14 16 Olefin Sulfonate:
Sodium C14-16 Olefin Sulfonate is a surfactant derived from olefin, a type of hydrocarbon. It is commonly used in cosmetics as a cleansing agent and emulsifier.2. Use:
Sodium C14-16 Olefin Sulfonate is used in various cosmetic products such as shampoos, body washes, facial cleansers, and hand soaps. It helps to remove dirt, oil, and other impurities from the skin and hair, leaving them clean and refreshed.3. Usage Sodium C14 16 Olefin Sulfonate:
When using products containing Sodium C14-16 Olefin Sulfonate, it is important to follow the instructions provided on the packaging. It is typically used by applying the product to wet skin or hair, lathering it up, and then rinsing thoroughly with water. It is advisable to avoid getting the product in the eyes, and if contact occurs, rinse immediately with water. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before regular use.4. References:
- "Sodium C14-16 Olefin Sulfonate" in CosmeticsInfo.org
- "Safety Assessment of Sodium C14-16 Olefin Sulfonate" in the International Journal of Toxicology
- "Formulation and Evaluation of Shampoo Containing Sodium C14-16 Olefin Sulfonate" in the Journal of Cosmetic Science.
Sodium Lactate
1. Definition Sodium Lactate:
Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.2. Use:
Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.3. Usage Sodium Lactate:
When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.4. References:
- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.
- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.
Sodium Pca
1. Definition Sodium Pca:
Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.2. Use:
Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.3. Usage Sodium Pca:
When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.4. References:
- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.
Tocopheryl Acetate
1. Definition Tocopheryl Acetate:
Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.2. Use:
Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.3. Usage Tocopheryl Acetate:
When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.4. References:
- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate
- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html
- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits
Triethanolamine
1. Definition Triethanolamine:
Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.2. Use:
Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.3. Usage Triethanolamine:
While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.4. References:
- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine
- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf
- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120
Valine
1. Definition Valine:
Valine is an essential amino acid that plays a crucial role in protein synthesis and muscle growth. It is one of the three branched-chain amino acids (BCAAs) along with leucine and isoleucine.2. Use:
Valine is commonly used in cosmetics for its skin conditioning properties. It helps to improve the texture and appearance of the skin by promoting hydration and maintaining the skin's natural moisture balance. Valine also has antioxidant properties that help to protect the skin from environmental damage and premature aging.3. Usage Valine:
Valine can be found in a variety of cosmetic products such as moisturizers, serums, and creams. It is typically included in formulations at concentrations ranging from 0.1% to 2%. Valine is generally well-tolerated by most skin types, but it is always recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.4. References:
- Takahashi, H., et al. (2019). Effects of branched-chain amino acids on skin aging. Journal of Dermatological Science, 94(1), 221-225.
- Pappas, A., et al. (2017). The role of amino acids in skin health. Journal of Clinical and Aesthetic Dermatology, 10(7), 19-27.
- Zhang, L., et al. (2015). Valine ameliorates LPS-induced inflammation in human bronchial epithelial cells. Inflammation, 38(5), 1740-1748.
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Sodium Laureth Sulfate
1. Definition Sodium Laureth Sulfate:
Sodium Laureth Sulfate is a surfactant and detergent commonly used in cosmetics and personal care products. It is a type of sulfate that helps to create a foaming lather and cleanse the skin or hair by removing dirt and oils.2. Use:
Sodium Laureth Sulfate is often found in products such as shampoos, body washes, facial cleansers, and toothpaste. It is used to create a rich lather that effectively removes dirt, oils, and impurities from the skin or hair.3. Usage Sodium Laureth Sulfate:
While Sodium Laureth Sulfate is considered safe for use in cosmetics, some people may experience skin irritation or sensitivity to this ingredient. It is important to patch test products containing Sodium Laureth Sulfate before using them regularly, especially if you have sensitive skin. Additionally, it is recommended to avoid getting products containing this ingredient in your eyes, as it can cause irritation.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 23665879, Sodium Laureth Sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-laureth-sulfate
- Environmental Working Group. Sodium Laureth Sulfate. https://www.ewg.org/skindeep/ingredients/706089-SODIUM_LAURETH_SULFATE/
- Cosmeticsinfo.org. Sodium Laureth Sulfate. http://cosmeticsinfo.org/ingredient/sodium-laureth-sulfate
Sodium Chloride
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Cocamidopropyl Betaine
1. Definition Cocamidopropyl Betaine:
Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.2. Use:
Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.3. Usage Cocamidopropyl Betaine:
When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine
- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/
- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/
Dimethiconol
1. Definition Dimethiconol:
Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.2. Use:
Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.3. Usage Dimethiconol:
Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.4. References:
- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.
- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.
- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Tea Dodecylbenzenesulfonate
1. Definition Tea Dodecylbenzenesulfonate:
Tea Dodecylbenzenesulfonate is a surfactant commonly used in cosmetics and personal care products. It is a type of anionic surfactant that helps to cleanse the skin by removing dirt, oil, and other impurities.2. Use:
Tea Dodecylbenzenesulfonate is used in a variety of cosmetic products such as cleansers, shampoos, body washes, and facial scrubs. It helps to create a lather and improve the spreadability of products, making them more effective at cleansing the skin and hair.3. Usage Tea Dodecylbenzenesulfonate:
When using products containing Tea Dodecylbenzenesulfonate, it is important to follow the instructions provided on the packaging. It is generally safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient to ensure that it is suitable for your skin.Precautions: While Tea Dodecylbenzenesulfonate is considered safe for use in cosmetics, it is always important to use products containing this ingredient as directed. Avoid contact with the eyes and rinse thoroughly with water if contact occurs. If irritation or allergic reactions occur, discontinue use and consult a healthcare professional.
4. References:
- "Safety Assessment of Tea Dodecylbenzenesulfonate as Used in Cosmetics" by the Cosmetic Ingredient Review, 2019.
- "Surfactants in Cosmetics" by R. M. Pearson, 2006.
- "Formulating, Packaging, and Marketing of Cosmetic Products" by Nava Dayan and Lambros Kromidas, 2011.
Citric Acid
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
Guar Hydroxypropyltrimonium Chloride
1. Definition Guar Hydroxypropyltrimonium Chloride:
Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of Guar Gum, a natural polymer derived from the guar plant. It is commonly used in cosmetics as a conditioning agent and thickening agent.2. Use:
Guar Hydroxypropyltrimonium Chloride is primarily used in hair care products such as shampoos, conditioners, and hair masks. It helps to improve the manageability, softness, and overall appearance of the hair by providing conditioning benefits. It also helps to reduce static and frizz, making the hair easier to style.3. Usage Guar Hydroxypropyltrimonium Chloride:
Guar Hydroxypropyltrimonium Chloride is typically used in hair care products at concentrations ranging from 0.1% to 2%. It is added to the water phase of the formulation and should be thoroughly mixed to ensure uniform distribution. It is important to follow the recommended usage levels to avoid potential irritation or adverse effects on the skin or scalp.Precautions: While Guar Hydroxypropyltrimonium Chloride is considered safe for use in cosmetics, individuals with sensitive skin or scalp may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient and to discontinue use if any adverse reactions occur.
4. References:
- Sharma, S., et al. (2015). Guar gum: Processing, properties and food applications—A Review. Journal of Food Science and Technology, 52(2), 654-665.
- Lodeiro, C., et al. (2011). Guar gum as eco-friendly corrosion inhibitor for carbon steel in hydrochloric acid medium. Industrial & Engineering Chemistry Research, 50(11), 6837-6845.
- Prasad, K., et al. (2018). Guar gum: A versatile material for pharmaceutical industry. International Journal of Pharmaceutical Sciences and Research, 9(4), 1412-1421.
Laureth 23
1. Definition Laureth 23:
Laureth 23 is a polyethylene glycol ether of lauryl alcohol, commonly used in cosmetics and personal care products as an emulsifier, surfactant, and cleansing agent. It is known for its ability to help ingredients mix together and create a smooth texture in various skincare and haircare products.2. Use:
Laureth 23 is often included in formulations such as creams, lotions, shampoos, and conditioners to improve the texture and consistency of the product. It can also help to enhance the spreadability of skincare products and aid in the removal of dirt and oil from the skin and hair.3. Usage Laureth 23:
When using products containing Laureth 23, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Laureth 23 to ensure compatibility with your skin.4. References:
- Steinmetz, W. E., & Vogt, T. C. (2016). Surfactants in consumer products: Theory, technology and application. Springer.
- Cosmetic Ingredient Review. (2005). Final report on the safety assessment of laureth-23. International Journal of Toxicology, 24(4), 79-94.
- Personal Care Products Council. (2020). Safety Assessment of Laureth-23. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr766.pdf
Disodium Edta
1. Definition Disodium Edta:
Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.2. Use:
Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.3. Usage Disodium Edta:
Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.
- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/
- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Sodium Hydroxide
1. Definition Sodium Hydroxide:
Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.2. Use:
Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.3. Usage Sodium Hydroxide:
When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.4. References:
- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.
- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/
- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide
Ppg 7
1. Definition Ppg 7:
Ppg 7 is a polyethylene glycol derivative that is commonly used in cosmetics as an emulsifier, surfactant, and solvent. It is a synthetic compound that helps to stabilize and blend different ingredients in cosmetic formulations.2. Use:
Ppg 7 is used in cosmetics to create a smooth and even texture in products such as lotions, creams, and makeup. It helps to improve the spreadability of products and enhance their overall performance. Ppg 7 also acts as a moisturizer and can help to hydrate the skin when used in skincare products.3. Usage Ppg 7:
When using products containing Ppg 7, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or allergic reactions when using products with Ppg 7, so it is recommended to perform a patch test before using a new product. Additionally, it is important to follow the instructions on the product label and avoid using products containing Ppg 7 in sensitive areas such as around the eyes.4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 442153, Polyethylene glycol 7. https://pubchem.ncbi.nlm.nih.gov/compound/Polyethylene-glycol-7
- Cosmetics Info. Polyethylene glycol (PEG) compounds. https://cosmeticsinfo.org/ingredient/polyethylene-glycol-peg-compounds
- Personal Care Products Council. Ppg-7. https://www.cosmeticsinfo.org/ingredient/ppg-7
Hydrolyzed Pearl
1. Definition Hydrolyzed Pearl:
Hydrolyzed Pearl is a cosmetic ingredient derived from pearls that have undergone a hydrolysis process, breaking down the proteins and minerals into smaller molecules. This process enhances the absorption of the nutrients by the skin, making it a popular ingredient in skincare products.2. Use:
Hydrolyzed Pearl is commonly used in skincare products for its brightening, anti-aging, and skin-repairing properties. It is known to help improve skin texture, reduce the appearance of dark spots and hyperpigmentation, and promote collagen production. Additionally, it provides hydration and nourishment to the skin, leaving it looking radiant and youthful.3. Usage Hydrolyzed Pearl:
When using skincare products containing Hydrolyzed Pearl, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.4. References:
- Lee, S. H., & Kim, H. J. (2011). A novel whitening compound, hydrolyzed pearl, prevents UVB-induced skin pigmentation through inhibition of melanin production. Biological & Pharmaceutical Bulletin, 34(5), 517-522.
- Hwang, J. H., Park, S. H., Choi, Y. S., Kim, D. H., Kim, M. J., Kim, J. M., & Lee, J. Y. (2018). Anti-inflammatory effects of hydrolyzed pearl powder in in-vitro and in-vivo models of atopic dermatitis. Journal of Ethnopharmacology, 213, 256-261.
- Wu, X., Li, L., Li, Y., Liu, Y., & Ma, Y. (2017). Preparation and evaluation of hydrolyzed pearl powder as a novel anti-aging ingredient in cosmetics. Journal of Cosmetic Dermatology, 16(3), 371-378.