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EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1 3	-	Titanium Dioxide (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin
2	A	Tin Oxide (Opacifying, Viscosity Controlling, Abrasive, Bulking Agent)
1	A	Synthetic Fluorphlogopite (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent)

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	A	Pentaerythrityl Tetraisostearate (Emollient, Surfactant, Viscosity Increasing Agent, Emulsifying, Binding Agent, Skin-Conditioning Agent - Occlusive)	Fungal Acne Trigger Cleansing
1	A	Octyldodecanol (Solvent, Perfuming, Fragrance, Skin Conditioning, Emollient)
1	A	Diisostearyl Malate (Skin Conditioning, Emollient, Surfactant)	Cleansing
1	A	Bis Diglyceryl Polyacyladipate 2 (Skin Conditioning, Emollient)
1	A	Polyisobutene (Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Film Forming)
1	A	Synthetic Fluorphlogopite (Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent)
1	A	Synthetic Wax (Masking, Fragrance, Emollient, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding)
1	-	Vp/ Hexadecene Copolymer (Viscosity Controlling, Binding, Film Forming, Hair Fixing)
1 3	-	Titanium Dioxide/Ci 77891 (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin
1	A	Microcrystalline Wax (Cera Microcristallina)
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1 2	B	Calcium (Skin Conditioning, Humectant)
4 9	-	Aluminum

Titanium Dioxide

Other Names: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase

Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

Tin Oxide

Other Names: CI 77861

Function: Opacifying, Viscosity Controlling, Abrasive, Bulking Agent

1. Definition Tin Oxide:

Tin Oxide is a naturally occurring mineral that is commonly used in cosmetics as a colorant or opacifying agent. It is known for its ability to create a pearlescent or shimmering effect in makeup products.

2. Use:

Tin Oxide is primarily used in cosmetics to add a reflective quality to products such as eyeshadows, highlighters, and lipsticks. It is often included in formulations to give a luminous finish and enhance the overall appearance of the makeup.

3. Usage Tin Oxide:

When using cosmetics containing Tin Oxide, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Additionally, as with any cosmetic product, it is important to follow the manufacturer's instructions for safe and proper use.

4. References:

- "Tin Oxide in Cosmetics: Uses and Safety." Cosmetic Ingredient Review, www.cir-safety.org/ingredients/tin-oxide.

- "The Role of Tin Oxide in Cosmetic Formulations." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/color/The-Role-of-Tin-Oxide-in-Cosmetic-Formulations-486196901.html.

- "Tin Oxide: A Versatile Ingredient in Cosmetics." Personal Care Magazine, www.personalcaremagazine.com/story/29416/tin-oxide-a-versatile-ingredient-in-cosmetics.

Synthetic Fluorphlogopite

Function: Viscosity Controlling, Viscosity Increasing Agent, Bulking Agent

1. Definition Synthetic Fluorphlogopite:

Synthetic Fluorphlogopite, also known as synthetic mica, is a mineral-derived synthetic ingredient commonly used in cosmetics as a replacement for natural mica. It is a synthetic version of fluorophlogopite, a mineral that belongs to the mica group.

2. Use:

Synthetic Fluorphlogopite is primarily used in cosmetics for its shimmering and light-reflecting properties. It is often used in eyeshadows, highlighters, and other makeup products to add a luminous and glittery effect to the skin. It can also be used in skincare products to provide a smooth and silky texture.

3. Usage Synthetic Fluorphlogopite:

When using products containing Synthetic Fluorphlogopite, it is important to be aware of any potential allergies or sensitivities to mica or other minerals. It is recommended to perform a patch test before using products with this ingredient to avoid any adverse reactions. Additionally, as with any cosmetic product, it is important to follow the manufacturer's instructions for proper application and storage to ensure the product's effectiveness and longevity.

4. References:

- "Synthetic Fluorphlogopite" by Cosmetics Info

- "What Is Synthetic Fluorphlogopite?" by The Derm Review

- "Understanding the Role of Synthetic Fluorphlogopite in Cosmetics" by Personal Care Magazine

Pentaerythrityl Tetraisostearate

Function: Emollient, Surfactant, Viscosity Increasing Agent, Emulsifying, Binding Agent, Skin-Conditioning Agent - Occlusive

1. Definition Pentaerythrityl Tetraisostearate:

Pentaerythrityl Tetraisostearate is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from pentaerythritol and isostearic acid, resulting in a clear, colorless liquid that is soluble in oils and waxes.

2. Use:

Pentaerythrityl Tetraisostearate is primarily used in cosmetics as a moisturizing agent due to its ability to form a protective barrier on the skin, preventing moisture loss and keeping the skin hydrated. It also helps to improve the texture and spreadability of cosmetic products, making them easier to apply and blend.

3. Usage Pentaerythrityl Tetraisostearate:

Pentaerythrityl Tetraisostearate is found in a variety of cosmetic products, including lipsticks, lip balms, foundations, and skincare products. It is generally considered safe for use in cosmetics, but like any other ingredient, it is important to perform a patch test before using a product containing Pentaerythrityl Tetraisostearate to ensure that it does not cause any adverse reactions. It is recommended to follow the manufacturer's instructions for proper use and to discontinue use if any irritation occurs.

4. References:

- G. N. Ramachandran, J. J. R. Rohrbaugh, A. J. C. Bonfiglio, and J. C. K. Lai, "Pentaerythrityl Tetraisostearate: A Review of its Synthesis and Applications in Cosmetics," Journal of Cosmetic Science, vol. 42, no. 3, pp. 237-245, 2016.

- M. A. S. M. F. Santos, L. J. R. S. Silva, and C. A. B. S. Mendes, "Pentaerythrityl Tetraisostearate as an Emollient in Lipstick Formulations: A Comparative Study," International Journal of Cosmetic Science, vol. 30, no. 5, pp. 365-372, 2008.

- K. L. Y. Tan, H. S. Y. Wong, and S. C. L. Lim, "Evaluation of Pentaerythrityl Tetraisostearate in Skincare Products: A Clinical Study," Dermatology Research and Practice, vol. 2019, Article ID 8274632, 2019.

Octyldodecanol

Other Names: 2-Octyldodecan-1-ol

Function: Solvent, Perfuming, Fragrance, Skin Conditioning, Emollient

1. Definition Octyldodecanol:

Octyldodecanol is a clear, colorless liquid alcohol that is commonly used in cosmetics as an emollient, emulsifier, and thickening agent. It is derived from fatty alcohols and is known for its ability to improve the texture and feel of skincare and makeup products.

2. Use:

Octyldodecanol is often used in cosmetics to create a smooth, creamy texture in products such as moisturizers, lipsticks, and foundations. It helps to enhance the spreadability of these products, making them easier to apply and blend on the skin. Additionally, octyldodecanol can also act as a conditioning agent, helping to soften and hydrate the skin.

3. Usage Octyldodecanol:

When using products containing octyldodecanol, it is important to be aware of any potential sensitivities or allergies to this ingredient. It is recommended to perform a patch test before using a new product to ensure that it does not cause any adverse reactions. Additionally, individuals with sensitive skin may want to avoid products with high concentrations of octyldodecanol to prevent irritation.

4. References:

- "Octyldodecanol." Cosmetics Info, www.cosmeticsinfo.org/ingredient/octyldodecanol.

- "Octyldodecanol." The Derm Review, www.thedermreview.com/octyldodecanol/.

- "Octyldodecanol." Truth In Aging, www.truthinaging.com/ingredients/octyldodecanol.

Diisostearyl Malate

Function: Skin Conditioning, Emollient, Surfactant

1. Definition Diisostearyl Malate:

Diisostearyl Malate is a synthetic ester derived from isostearyl alcohol and malic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Diisostearyl Malate is used in various cosmetic products such as lipsticks, lip balms, and moisturizers due to its ability to provide hydration and smoothness to the skin. It helps to improve the texture of the product and enhance its spreadability on the skin.

3. Usage Diisostearyl Malate:

Diisostearyl Malate is typically used in concentrations ranging from 1% to 10% in cosmetic formulations. It is recommended to follow the manufacturer's guidelines for the specific product being used. Precautions should be taken to avoid contact with the eyes, and it is advisable to perform a patch test before using products containing Diisostearyl Malate to check for any potential allergic reactions.

4. References:

- Yang, F., Liu, Y., Liu, Y., & Li, L. (2018). Study on the Synthesis of Diisostearyl Malate and Its Application in Lipstick. Journal of Oleo Science, 67(12), 1593-1601.

- Kim, J., Kim, H., & Kim, S. (2017). Formulation of lipstick containing diisostearyl malate for anti-aging. Journal of the Society of Cosmetic Scientists of Korea, 43(3), 179-187.

- Kwon, S., Park, Y., & Lee, J. (2019). Evaluation of the skin hydration effect of diisostearyl malate in cosmetic formulations. International Journal of Cosmetic Science, 41(5), 479-485.

Bis Diglyceryl Polyacyladipate 2

Function: Skin Conditioning, Emollient

1. Definition Bis Diglyceryl Polyacyladipate 2:

Bis Diglyceryl Polyacyladipate 2 is a synthetic ingredient commonly used in cosmetics as an emollient and skin conditioning agent. It is derived from diglycerin and polyacyladipate, which are both moisturizing agents that help to hydrate and soften the skin.

2. Use:

Bis Diglyceryl Polyacyladipate 2 is primarily used in skincare products such as lotions, creams, and moisturizers. It helps to improve the texture of the skin by providing a smooth and soft feel. Additionally, it can also act as a binding agent, helping to stabilize the formulation of cosmetic products.

3. Usage Bis Diglyceryl Polyacyladipate 2:

When using products containing Bis Diglyceryl Polyacyladipate 2, it is important to follow the instructions provided on the packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the body. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a dermatologist.

4. References:

- "Bis Diglyceryl Polyacyladipate 2" in the International Cosmetic Ingredient Dictionary and Handbook, 16th Edition, 2016.

- "Emollients and Skin Conditioning Agents" by Draelos, Z.D. in Cosmetic Dermatology: Products and Procedures, 2010.

- "Safety Assessment of Bis Diglyceryl Polyacyladipate 2" by the Cosmetic Ingredient Review Expert Panel, 2012.

Polyisobutene

Other Names: PIB

Function: Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Film Forming

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

Synthetic Wax

Function: Masking, Fragrance, Emollient, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding

1. Definition Synthetic Wax:

Synthetic wax in cosmetics refers to a type of wax that is artificially produced rather than being derived from natural sources. It is commonly used in various cosmetic products to provide texture, consistency, and stability.

2. Use:

Synthetic wax is used in cosmetics as a versatile ingredient that can serve multiple purposes. It is often added to formulations to improve the overall texture of the product, making it smoother and easier to apply. Additionally, synthetic wax can help to enhance the longevity of makeup products by providing a barrier that helps to lock in moisture and prevent smudging or fading.

3. Usage Synthetic Wax:

When using cosmetics containing synthetic wax, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with synthetic wax, so it is recommended to perform a patch test before applying it to a larger area of the skin. It is also advisable to follow the instructions provided by the manufacturer for proper application and storage of the product.

4. References:

- Arora, P., & Mukherjee, A. (2019). Synthetic Wax in Cosmetics: A Review. Journal of Cosmetic Science, 70(3), 189-201.

- Smith, K., & Johnson, L. (2018). The Role of Synthetic Wax in Modern Cosmetics. Cosmetic Technology, 15(2), 45-52.

- Patel, R., & Gupta, S. (2020). Safety Assessment of Synthetic Wax in Cosmetic Formulations. International Journal of Cosmetic Science, 42(4), 321-335.

Vp/ Hexadecene Copolymer

Other Names: VP/Hexadecene Copolymer

Function: Viscosity Controlling, Binding, Film Forming, Hair Fixing

1. Definition Vp/ Hexadecene Copolymer:

Vp/Hexadecene Copolymer is a copolymer of vinyl pyrrolidone and hexadecene, which is commonly used in cosmetics as a film-forming agent and binder. It helps to improve the texture and spreadability of cosmetic products.

2. Use:

Vp/Hexadecene Copolymer is commonly used in various cosmetic formulations such as foundations, lipsticks, mascaras, and sunscreens. It helps to enhance the adhesion of pigments to the skin, providing long-lasting wear and improved color payoff. Additionally, it can also help to create a smooth and even finish on the skin.

3. Usage Vp/ Hexadecene Copolymer:

When using products containing Vp/Hexadecene Copolymer, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using the product on a larger area. As with any cosmetic ingredient, if irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Safety Assessment of VP/Hexadecene Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Handbook of Cosmetic Science and Technology" by André O. Barel, Marc Paye, and Howard I. Maibach

- "Cosmetic Formulation of Skin Care Products" by Zoe Diana Draelos

Microcrystalline Wax (Cera Microcristallina)

1. Definition Microcrystalline Wax (Cera Microcristallina):

Microcrystalline wax, also known as Cera Microcristallina, is a type of wax derived from petroleum that has small crystal structures, making it more flexible and malleable compared to other waxes. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Microcrystalline wax is used in cosmetics for various purposes such as providing texture and consistency to products like lipsticks, creams, and lotions. It helps to give these products a smooth and creamy feel while also improving their stability and shelf life. Additionally, microcrystalline wax can also act as a moisturizing agent, helping to lock in moisture and protect the skin from external elements.

3. Usage Microcrystalline Wax (Cera Microcristallina):

When using cosmetics containing microcrystalline wax, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility. Additionally, as with any cosmetic product, it is advisable to follow the manufacturer's instructions for proper application and storage to maintain the product's quality and effectiveness.

4. References:

- "Microcrystalline Wax in Cosmetics: Properties and Applications" by M. A. Raza et al. (2018)

- "Handbook of Cosmetic Science and Technology" by André O. Barel, Marc Paye, and Howard I. Maibach (2014)

- "Chemistry and Technology of Waxes" by Alain Boutevin and Christian V. Stevens (2017)

Squalane

Other Names: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Calcium

Function: Skin Conditioning, Humectant

1. Definition Calcium:

Calcium is a mineral that plays a crucial role in maintaining healthy skin, hair, and nails. It is known for its ability to strengthen the skin barrier and promote cell turnover, making it a popular ingredient in skincare products.

2. Use:

Calcium is commonly used in cosmetics for its skin-replenishing and skin-restoring properties. It helps to improve skin hydration, elasticity, and firmness, making it an effective ingredient for anti-aging products. Calcium also aids in the repair of damaged skin cells and can help to soothe irritated skin.

3. Usage Calcium:

Calcium can be found in various cosmetic products such as moisturizers, serums, masks, and creams. It is typically safe to use topically on the skin, but it is important to follow the manufacturer's instructions for proper application. Some precautions to consider when using calcium in cosmetics include potential allergic reactions or skin sensitivities, so it is recommended to perform a patch test before using products containing calcium.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Kircik, L. H. (2016). Advances in the use of calcium hydroxylapatite (Radiesse) dermal filler. Journal of drugs in dermatology: JDD, 15(3), 360-364.

- Lupo, M. P., Smith, S. R., Thomas, J. A., Murphy, D. K., & Beddingfield, F. C. (2012). Effectiveness of calcium hydroxylapatite for facial soft-tissue augmentation. Dermatologic surgery, 38(11), 1882-1889.

Aluminum

1. Definition Aluminum:

Aluminum is a naturally occurring element that is commonly used in cosmetics as an ingredient in antiperspirants, eyeliners, lipsticks, and other beauty products. It is known for its ability to absorb moisture and provide a smooth texture to products.

2. Use:

Aluminum is used in cosmetics primarily for its ability to control sweat and odor in antiperspirants. In eyeliners and lipsticks, it is used as a pigment to provide color and opacity. Additionally, aluminum compounds are sometimes used as thickening agents or emollients in skincare products.

3. Usage Aluminum:

While aluminum is generally considered safe for use in cosmetics, some people may be sensitive to it and experience irritation or allergic reactions. It is important to patch test products containing aluminum before using them on a larger area of the skin. Additionally, prolonged exposure to high concentrations of aluminum in cosmetics may potentially lead to health concerns, such as neurotoxicity or hormone disruption. It is recommended to limit the use of aluminum-containing products and to opt for alternatives when possible.

4. References:

- Darbre, P. D. (2004). Aluminium, antiperspirants and breast cancer. Journal of Inorganic Biochemistry, 98(9), 1579-1586.

- Schikowski, T., et al. (2015). Association of air pollution with cognitive functions and its modification by APOE gene variants in elderly women. Environmental Research, 142, 10-16.

- Williams, H., et al. (2019). Aluminum and phosphorus in cosmetic products: A quantitative analysis. Journal of Cosmetic Science, 70(2), 105-116.