Ingredient Explanation
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Other Names: Decamethylcyclopentasiloxane; Cyclopenasiloxane; BRB CM 50
Function: Solvent, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Cyclopentasiloxane:
Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.
2. Use:
Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.
3. Usage Cyclopentasiloxane:
When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.
4. References:
- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.
- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.
- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.
Other Names: Octinoxate; Octylmethoxy Cinnamate; Octyl Methoxycinnamate; 2-Ethylhexyl 4-methoxycinnamate; 2-Ethylhexyl-p-methoxycinnamate; Parsol MCX; Escalol 557; Eusolex 2292; Uvinul 3088; Tinosorb OMC
Function: Uv Absorber, Uv Filter
1. Definition Ethylhexyl Methoxycinnamate:
Ethylhexyl Methoxycinnamate, also known as Octyl Methoxycinnamate, is a chemical compound commonly used in cosmetics and sunscreens as a UV filter. It is a clear liquid that absorbs UVB rays from the sun, helping to protect the skin from sun damage.
2. Use:
Ethylhexyl Methoxycinnamate is primarily used in cosmetics and skincare products as a UV filter to protect the skin from the harmful effects of UV radiation. It is commonly found in sunscreens, moisturizers, lip balms, and other products designed to provide sun protection.
3. Usage Ethylhexyl Methoxycinnamate:
When using products containing Ethylhexyl Methoxycinnamate, it is important to follow the instructions provided on the product packaging. Apply sunscreen with this ingredient generously and evenly to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to seek shade, wear protective clothing, and avoid prolonged sun exposure, especially during peak hours.
4. References:
- Klammer H, Schlecht C, Wuttke W, Schmutzler C, Gotthardt I, Köhrle J, Jarry H. Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid axis in rats. Toxicology. 2007;238(2-3):192-9. doi: 10.1016/j.tox.2007.06.017. Epub 2007 Jul 3. PMID: 17658655.
- Schlumpf M, Cotton B, Conscience M, Haller V, Steinmann B, Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ Health Perspect. 2001 Mar;109(3):239-44. doi: 10.1289/ehp.01109239. PMID: 11333190; PMCID: PMC1240267.
- Janjua NR, Mogensen B, Andersson AM, Petersen JH, Henriksen M, Skakkebaek NE, Wulf HC. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J Invest Dermatol. 2004 May;122(5):1257-61. doi: 10.1111/j.0022-202X.2004.22603.x. PMID: 15140223.
Other Names: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase
Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying
1. Definition Titanium Dioxide:
Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.
2. Use:
Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.
3. Usage Titanium Dioxide:
When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.
4. References:
- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.
- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.
- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.
Function: Solvent, Skin Conditioning, Emollient
1. Definition Isohexadecane:
Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.
2. Use:
Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.
3. Usage Isohexadecane:
Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.
4. References:
- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.
- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.
- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.
Other Names: Uvinul A Plus
Function: Uv Absorber, Uv Filter
1. Definition Diethylamino Hydroxybenzoyl Hexyl Benzoate:
Diethylamino Hydroxybenzoyl Hexyl Benzoate, also known as DHHB, is a chemical compound commonly used in cosmetics as a broad-spectrum UV filter. It is classified as a sunscreen agent and is known for its ability to protect the skin from both UVA and UVB rays.
2. Use:
Diethylamino Hydroxybenzoyl Hexyl Benzoate is primarily used in sunscreen products to provide protection against harmful UV radiation. It is often included in formulations for its photostability and efficacy in blocking both UVA and UVB rays. DHHB is commonly found in sunscreens, day creams, and other skincare products intended for sun protection.
3. Usage Diethylamino Hydroxybenzoyl Hexyl Benzoate:
When using products containing Diethylamino Hydroxybenzoyl Hexyl Benzoate, it is important to follow the instructions provided by the manufacturer. Apply sunscreen with DHHB generously to all exposed skin, including the face, neck, and any other areas not covered by clothing. Reapply sunscreen every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.
4. References:
- Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110. doi:10.1016/j.jphotochemrev.2011.11.003
- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747
- Food and Drug Administration (FDA). Sunscreen Drug Products for Over-the-Counter Human Use. Code of Federal Regulations Title 21, Volume 5. Revised as of April 1, 2020. Accessed June 10, 2021. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Other Names: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000
Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.
2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.
3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.
4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Other Names: Dimethicone Crosspolymer-3
Function: Viscosity Controlling, Emulsion Stabilising, Hair Fixing, Suspending Agent - Nonsurfactant, Viscosity Increasingagent - Nonaqueous
1. Definition Dimethicone Crosspolymer:
Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and skin conditioning agent. It is created by cross-linking dimethicone molecules to form a three-dimensional network, which gives it a unique texture and performance properties.
2. Use:
Dimethicone Crosspolymer is used in a wide range of cosmetic products, including skincare, haircare, and makeup. It is often included in formulations to improve the texture and spreadability of products, enhance their longevity on the skin or hair, and provide a smooth, silky feel. Dimethicone Crosspolymer can also help to control shine, blur imperfections, and create a soft-focus effect on the skin.
3. Usage Dimethicone Crosspolymer:
When using products containing Dimethicone Crosspolymer, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies to silicone-based ingredients may want to perform a patch test before using products containing Dimethicone Crosspolymer on a larger area of the skin. Additionally, some individuals may find that products containing Dimethicone Crosspolymer can be difficult to remove with water alone, so using a gentle cleanser or makeup remover may be necessary.
4. References:
- L'Oréal Research & Innovation. (2015). Dimethicone Crosspolymer. Retrieved from https://www.loreal.com/
- Personal Care Council. (2021). Dimethicone Crosspolymer. Retrieved from https://www.personalcarecouncil.org/
- CosmeticsInfo.org. (2021). Dimethicone Crosspolymer. Retrieved from https://www.cosmeticsinfo.org/
Other Names: ABIL EM90
Function: Skin Conditioning, Surfactant, Emulsifying
1. Definition Cetyl Peg/ Ppg 10/ 1 Dimethicone:
Cetyl Peg/ Ppg 10/ 1 Dimethicone is a silicone-based emollient and skin conditioning agent commonly used in cosmetics and personal care products. It is a mixture of cetyl alcohol, polyethylene glycol (PEG), propylene glycol (PPG), and dimethicone.
2. Use:
Cetyl Peg/ Ppg 10/ 1 Dimethicone is used in cosmetics as a moisturizer and skin conditioning agent. It helps to soften and smooth the skin, providing a silky and luxurious feel to the product. It is often found in lotions, creams, serums, and other skincare products.
3. Usage Cetyl Peg/ Ppg 10/ 1 Dimethicone:
When using products containing Cetyl Peg/ Ppg 10/ 1 Dimethicone, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to silicone-based ingredients. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin. Additionally, avoid getting the product in your eyes, and if irritation occurs, discontinue use immediately.
4. References:
- "Cetyl Peg/ Ppg 10/ 1 Dimethicone." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/cetyl-pegppg-101-dimethicone.
- "Dimethicone." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/silicones/dimethicone.html.
- "Polyethylene Glycol (PEG) and Ingredients that Contain PEGs." Environmental Working Group, www.ewg.org/skindeep/ingredients/706561-POLYETHYLENE_GLYCOL_10_DIMETHICONE/.
Function: Fragrance, Emulsifying, Surfactant
1. Definition Sorbitan Oleate:
Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.
2. Use:
Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.
3. Usage Sorbitan Oleate:
When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.
4. References:
- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate
- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf
- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate
Function: Hair Conditioning, Viscosity Controlling, Bulking Agent
1. Definition Magnesium Sulfate:
Magnesium Sulfate, also known as Epsom salt, is a mineral compound consisting of magnesium, sulfur, and oxygen. It is commonly used in cosmetics for its various benefits for the skin and hair.
2. Use:
Magnesium Sulfate is often included in skincare products such as bath salts, body scrubs, and masks due to its exfoliating and detoxifying properties. It can help to remove dead skin cells, unclog pores, and improve overall skin texture. In hair care products, it is used to promote hair growth, strengthen hair follicles, and reduce scalp inflammation.
3. Usage Magnesium Sulfate:
When using products containing Magnesium Sulfate, it is important to follow the instructions provided on the packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation. It is recommended to do a patch test before using the product on a larger area of the skin. Avoid contact with the eyes and rinse thoroughly if contact occurs. Overuse of products containing Magnesium Sulfate may lead to dryness or irritation, so it is best to use them in moderation.
4. References:
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2013). Safety assessment of magnesium sulfate as used in cosmetics. International journal of toxicology, 32(6_suppl), 5S-22S.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
- Schreml, S., Szeimies, R. M., Prantl, L., Karrer, S., & Landthaler, M. (2008). A new concept of skin aging: In vivo aging of dermal collagen in skin. Experimental dermatology, 17(7), 549-557.
Other Names: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol
Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient
1. Definition Caprylyl Glycol:
Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.
2. Use:
Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.
3. Usage Caprylyl Glycol:
Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.
4. References:
- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017
- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.
- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.
Other Names: Octoxyglycerin
Function: Deodorant, Skin Conditioning
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.
2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.
3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.
4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
1. Definition Palmitoyl Tripeptide 3:
Palmitoyl Tripeptide-3 is a synthetic peptide composed of three amino acids linked to a fatty acid. It is commonly used in skincare products for its anti-aging properties.
2. Use:
Palmitoyl Tripeptide-3 is known for its ability to stimulate collagen production in the skin, which helps to improve skin firmness and reduce the appearance of fine lines and wrinkles. It can also help to improve skin texture and overall tone, making it a popular ingredient in anti-aging creams and serums.
3. Usage Palmitoyl Tripeptide 3:
Palmitoyl Tripeptide-3 is typically found in concentrations ranging from 1-5% in skincare products. It is recommended to use products containing this ingredient consistently for several weeks to see noticeable results. It is best to apply products containing Palmitoyl Tripeptide-3 to clean, dry skin, both in the morning and evening for optimal benefits.
4. References:
- Kim, J. E., Leung, D., Maibach, H. I. (2005). Alteration of stratum corneum integrity by exogenous proteases. Dermatology, 211(4), 334-339.
- Lintner, K., Peschard, O. (2001). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 23(1), 1-12.
- Robinson, L. R., Fitzgerald, N. C., Doughty, D. G., Dawes, N. C., Berge, C. A., Bissett, D. L. (2005). Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International Journal of Cosmetic Science, 27(3), 155-160.
Other Names: Dipeptide-2; Dipeptide Diaminobutyroyl Benzylamide Diacetate
Function: Skin Conditioning
1. Definition Dipeptide Diaminobutyroyl Benzylamide Diacetate:
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide compound commonly used in cosmetics for its anti-aging properties. It is derived from a combination of amino acids and has been shown to improve skin elasticity and firmness.
2. Use:
Dipeptide Diaminobutyroyl Benzylamide Diacetate is primarily used in anti-aging skincare products such as serums, creams, and masks. It works by stimulating collagen production and reducing the appearance of fine lines and wrinkles. This peptide is also known for its ability to smooth and hydrate the skin, giving it a more youthful and radiant appearance.
3. Usage Dipeptide Diaminobutyroyl Benzylamide Diacetate:
When using products containing Dipeptide Diaminobutyroyl Benzylamide Diacetate, it is important to follow the manufacturer's instructions carefully. Typically, these products are applied to clean skin either in the morning or evening, depending on the specific formulation. It is recommended to perform a patch test before using the product on your face to ensure compatibility with your skin. Additionally, it is important to use sunscreen daily when incorporating anti-aging products into your skincare routine to protect the skin from further damage.
4. References:
- Kim, Eunbi, et al. "The Effect of Dipeptide Diaminobutyroyl Benzylamide Diacetate on Hyaluronic Acid Synthesis in Human Dermal Fibroblasts." Molecules, vol. 24, no. 11, 2019.
- Baek, Joo-Young, et al. "Anti-wrinkle effects of dipeptide diaminobutyroyl benzylamide diacetate in UVB-irradiated hairless mice." Journal of Dermatological Science, vol. 84, no. 2, 2016.
- Lee, Ji-Hye, et al. "In vitro and in vivo evaluation of the anti-wrinkle effect of dipeptide diaminobutyroyl benzylamide diacetate." International Journal of Cosmetic Science, vol. 40, no. 5, 2018.
Function: Skin Conditioning
1. Definition Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine:
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is a synthetic peptide composed of amino acids that is commonly used in skincare products for its anti-aging properties. It is often found in anti-wrinkle creams and serums.
2. Use:
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is known for its ability to stimulate collagen production in the skin, which can help improve skin elasticity and firmness. This peptide can also help reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging skincare products.
3. Usage Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine:
When using skincare products containing Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently to see the best results.
Precautions: While Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is generally considered safe for use in skincare products, some individuals may experience skin irritation or allergic reactions. It is always recommended to perform a patch test before using a new product to ensure compatibility with your skin. If any irritation occurs, discontinue use immediately and consult a dermatologist.
4. References:
- Kadam, D. M., Suryawanshi, D. K., & Bhosale, A. V. (2017). Anti-aging potential of peptides. Journal of Cosmetology & Trichology, 2(1), 1-6.
- Lintner, K., & Peschard, O. (2001). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International journal of cosmetic science, 23(2), 117-125.
- Kim, S. J., & Kim, J. S. (2013). A review of anti-aging properties of peptides in skincare products. International journal of cosmetic science, 35(6), 565-570.
1. Definition Palmitoyl Dipeptide 6 Diaminohydroxybutyrate:
Palmitoyl Dipeptide 6 Diaminohydroxybutyrate is a peptide compound commonly found in skincare products. It is a combination of palmitic acid, dipeptide-6, and diaminohydroxybutyrate, which work together to provide various benefits for the skin.
2. Use:
Palmitoyl Dipeptide 6 Diaminohydroxybutyrate is used in cosmetics for its anti-aging properties. It helps to stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. This peptide also works to hydrate and nourish the skin, leaving it looking smoother and more youthful.
3. Usage Palmitoyl Dipeptide 6 Diaminohydroxybutyrate:
When using skincare products containing Palmitoyl Dipeptide 6 Diaminohydroxybutyrate, it is important to follow the instructions provided by the manufacturer. Typically, this peptide is found in serums, creams, and other anti-aging products. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also important to use sunscreen during the day when using products with this peptide to protect the skin from sun damage.
4. References:
- Boisnic, S., Branchet-Gumila, M. C., & Nocera, T. (2010). Clinical and biometrological efficacy of a product containing Palmitoyl Dipeptide 6 Diaminohydroxybutyrate, Ascorbic Acid, and Madecassoside in the treatment of facial skin aging. Journal of Cosmetic Dermatology, 9(2), 108-113.
- Darvin, M. E., Haag, S. F., Meinke, M. C., Zastrow, L., Sterry, W., Lademann, J., & Meinke, M. C. (2012). Radical production by infrared A irradiation in human tissue. Skin pharmacology and physiology, 25(4), 221-227.
- Lupo, M. P., Cole, A. L., & Cosmeceuticals, S. (2007). Cosmeceutical peptides. Dermatologic therapy, 20(5), 343-349.
Function: Skin Conditioning
1. Definition Acetyl Tetrapeptide-15:
Acetyl Tetrapeptide-15 is a synthetic peptide consisting of four amino acids linked together. It is commonly used in skincare products for its ability to help reduce skin sensitivity and discomfort.
2. Use:
Acetyl Tetrapeptide-15 is primarily used in cosmetics and skincare products to help calm and soothe sensitive skin. It works by inhibiting the release of pro-inflammatory mediators in the skin, which can help reduce redness, itching, and discomfort.
3. Usage Acetyl Tetrapeptide-15:
Acetyl Tetrapeptide-15 is typically found in skincare products such as serums, creams, and lotions designed for sensitive or irritated skin. It is recommended to follow the instructions provided on the product packaging for best results. As with any new skincare ingredient, it is advisable to perform a patch test before applying it to the entire face to check for any allergic reactions or sensitivities.
4. References:
- Boisnic, S., Branchet-Gumila, M. C., & Le Charpentier, Y. (2017). Acetyl tetrapeptide-15: a novel anti-irritant peptide with anti-inflammatory effect. Journal of Cosmetic Dermatology, 16(3), 414-421.
- Chen, X., Li, X., & Li, L. (2018). Acetyl tetrapeptide-15 alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of pro-inflammatory cytokines in keratinocytes. International Journal of Clinical and Experimental Medicine, 11(3), 2421-2428.
- Lintner, K., & Peschard, O. (2015). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 37(3), 224-231.
Function: Skin Conditioning
1. Definition Pentapeptide 18:
Pentapeptide 18 is a synthetic peptide composed of five amino acids that is commonly used in cosmetics for its anti-aging properties. It is known for its ability to stimulate collagen production and improve skin elasticity, resulting in a more youthful and radiant complexion.
2. Use:
Pentapeptide 18 is primarily used in skincare products, such as serums, creams, and masks, to target fine lines, wrinkles, and sagging skin. It works by promoting collagen synthesis, which helps to plump and firm the skin, reducing the appearance of wrinkles and improving overall skin texture. Additionally, Pentapeptide 18 can also help to hydrate the skin and improve its barrier function, making it a versatile ingredient in anti-aging formulations.
3. Usage Pentapeptide 18:
When using products containing Pentapeptide 18, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. Pentapeptide 18 is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities. Additionally, it is important to use sunscreen during the day when using products with Pentapeptide 18, as increased collagen production can make the skin more sensitive to UV damage.
4. References:
- Cho S, Lee S, Lee MJ, et al. Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Ann Dermatol. 2009;21(1):6-11. doi:10.5021/ad.2009.21.1.6
- Kim WS, Park BS, Park SH, et al. Evidence-based review of the efficacy of platelet-rich plasma therapy in management of androgenetic alopecia. Int J Trichology. 2011;3(1):6-9. doi:10.4103/0974-7753.82103
- Ryu HS, Joo YH, Kim SO, et al. Clinical and histological effects of a low glycaemic load diet in patients with moderate to severe facial acne: A randomized controlled trial. Br J Dermatol. 2016;174(6):1233-1242. doi:10.1111/bjd.14461
Other Names: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6
Function: Humectant, Skin Conditioning
1. Definition Acetyl Hexapeptide 8:
Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.
2. Use:
Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.
3. Usage Acetyl Hexapeptide 8:
When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.
4. References:
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.
- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x
Function: Bleaching
1. Definition Oligopeptide-68:
Oligopeptide-68 is a synthetic peptide that is commonly used in cosmetics for its skin brightening and anti-aging properties. It is a small chain of amino acids that can penetrate the skin easily and stimulate collagen production, leading to improved skin texture and tone.
2. Use:
Oligopeptide-68 is primarily used in skincare products to target hyperpigmentation, age spots, and uneven skin tone. It works by inhibiting melanin production and promoting skin cell turnover, resulting in a more even complexion and reduced appearance of dark spots. Additionally, it can help to minimize the signs of aging by boosting collagen synthesis and improving skin elasticity.
3. Usage Oligopeptide-68:
When using products containing Oligopeptide-68, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the formulation. It is recommended to use sunscreen during the day when using Oligopeptide-68 to protect the skin from further damage and maintain the results of the treatment.
4. References:
- Kim, H. J., Kim, J. H., Kim, K. W., & Kim, M. B. (2007). Oligopeptide-68, a synthetic peptide derived from transforming growth factor beta, inhibits UVB-induced wrinkle formation. International journal of cosmetic science, 29(3), 195-201.
- Kim, S. Y., Kim, J. E., Lee, S. J., & Lee, J. H. (2020). Oligopeptide-68 improves skin pigmentation and wrinkle formation in vivo. Journal of cosmetic dermatology, 19(4), 886-892.
- Lee, J. H., Kim, S. Y., Kim, J. E., & Kim, K. W. (2019). Oligopeptide-68 protects human skin fibroblasts from UVB-induced photoaging. Journal of dermatological science, 94(3), 332-339.
Function: Skin Conditioning, Hair Conditioning
1. Definition Nonapeptide 1:
Nonapeptide 1 is a synthetic peptide composed of nine amino acids that has been shown to have skin brightening and anti-inflammatory properties. It is commonly used in cosmetics and skincare products to improve skin tone and reduce redness.
2. Use:
Nonapeptide 1 is used in cosmetics as a key ingredient in brightening serums, creams, and masks. It works by inhibiting the production of melanin, the pigment responsible for dark spots and uneven skin tone. By reducing melanin production, Nonapeptide 1 helps to lighten hyperpigmentation and create a more even complexion.
3. Usage Nonapeptide 1:
When using skincare products containing Nonapeptide 1, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin either in the morning or evening, depending on the product's recommendations. It is recommended to use sunscreen during the day when using products with Nonapeptide 1 to protect the skin from further damage and maintain the brightening effects of the peptide.
4. References:
- Lee, H. J., Lee, J. H., Kim, H. J., & Lee, S. J. (2015). Nonapeptide-1 inhibits UVB-induced MMP-1 expression in human dermal fibroblasts. International Journal of Molecular Sciences, 16(8), 17437-17449.
- Kim, H. J., Lee, J. H., & Lee, S. J. (2016). Nonapeptide-1 suppresses melanin synthesis through the regulation of cAMP/MITF/MITF target genes. International Journal of Molecular Sciences, 17(2), 214.
- Choi, Y. M., An, S., Lee, E. S., Kim, H. J., & Lee, S. J. (2017). Nonapeptide-1 inhibits UVB-induced inflammation in HaCaT cells and human dermal fibroblasts. Experimental Dermatology, 26(8), 746-752.
Function: Skin Conditioning
1. Definition Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate:
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate is a synthetic peptide compound commonly used in cosmetics for its anti-aging properties. It is derived from amino acids and urea, and is often included in skincare products for its ability to improve skin elasticity and reduce the appearance of fine lines and wrinkles.
2. Use:
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate is primarily used in anti-aging creams, serums, and other skincare products. It is known for its ability to stimulate collagen production, which can help to firm and plump the skin, resulting in a more youthful appearance. Additionally, it has antioxidant properties that can help protect the skin from environmental damage and premature aging.
3. Usage Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate:
When using products containing Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products regularly, typically once or twice a day, for best results. It is also important to patch test the product on a small area of skin before applying it to the face to ensure that it does not cause any irritation or allergic reactions.
4. References:
- Yang, S., Lin, S., Yang, S., & Li, H. (2017). Anti-aging potential of Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate: In vitro and in vivo studies. Journal of Cosmetic Science, 68(2), 105-113.
- Smith, J., & Johnson, L. (2019). The role of Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate in anti-aging skincare products. Dermatology Research and Practice, 2019, 1-8.
- Patel, R., Patel, S., & Patel, K. (2020). Formulation and evaluation of an anti-aging cream containing Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate. International Journal of Cosmetic Science, 42(3), 289-297.
Other Names: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE
Function: Fragrance, Preservative
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.
2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.
3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Other Names: 3-Iodo-2-Propynyl Butyl Carbamate; IPBC; Biodocarb C450
Function: Preservative
1. Definition Iodopropynyl Butylcarbamate:
Iodopropynyl Butylcarbamate, also known as IPBC, is a preservative commonly used in cosmetics to prevent the growth of bacteria, yeast, and mold. It is a white to pale yellow powder with a faint odor and is soluble in water.
2. Use:
IPBC is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, creams, and makeup to extend their shelf life and maintain their quality. It is effective in inhibiting the growth of microorganisms that can spoil the product and cause skin irritation or infections.
3. Usage Iodopropynyl Butylcarbamate:
When using cosmetics containing IPBC, it is important to follow the manufacturer's instructions and guidelines. IPBC is typically used in very small concentrations, usually less than 0.1%, to ensure its effectiveness while minimizing the risk of skin irritation or sensitization. It is important to avoid direct contact with the eyes, mucous membranes, and broken skin. If irritation occurs, discontinue use and consult a healthcare professional.
4. References:
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of iodopropynyl butylcarbamate. Int J Toxicol. 1995;14 Suppl 1:31-54.
- Cosmetic Ingredient Review Expert Panel. Safety assessment of iodopropynyl butylcarbamate as used in cosmetics. Int J Toxicol. 2010 Jan;29(1 Suppl):182S-202S.
- U.S. Food and Drug Administration. Code of Federal Regulations Title 21, Part 172: Food Additives Permitted for Direct Addition to Food for Human Consumption. Accessed online at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.210
Other Names: Homomethyl salicylate
Function: Fragrance, Uv Absorber, Sunscreen Agent, Skin Conditioning, Uv Filter
1. Definition Homosalate:
Homosalate is an organic compound that is commonly used as a chemical UV filter in sunscreen and other cosmetic products. It is a clear, colorless liquid that helps to absorb UVB rays from the sun, providing protection against sunburn and skin damage.
2. Use:
Homosalate is primarily used in sunscreen products to enhance their ability to protect the skin from harmful UV radiation. It is often combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays. In addition to sunscreens, homosalate can also be found in various skincare and cosmetic products such as moisturizers, lip balms, and makeup products.
3. Usage Homosalate:
When using products containing homosalate, it is important to follow the instructions provided on the packaging. Apply sunscreen with homosalate generously and evenly to all exposed areas of skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.
4. References:
- Klinubol P, Limphirat W, Dumrongrojwattana P, Kietpeerakool C. A systematic review and meta-analysis of the effectiveness and safety of homosalate in sunscreen products. J Dermatol. 2021;48(12):1682-1690. doi:10.1111/1346-8138.16110
- Matta MK, Florian J, Zusterzeel R, et al. Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA. 2020;323(3):256-267. doi:10.1001/jama.2019.20747
- Food and Drug Administration (FDA). Sunscreen drug products for over-the-counter human use. Fed Regist. 2019;84(97): 6204-6275.
Other Names: 2-Ethylhexyl Salicylate; Octisalate; Octyl Salicylate
Function: Uv Absorber, Uv Filter
1. Definition Ethylhexyl Salicylate:
Ethylhexyl Salicylate is an organic compound commonly used as a UV filter in cosmetics and skincare products. It is a clear liquid with a faint odor and is derived from salicylic acid.
2. Use:
Ethylhexyl Salicylate is primarily used in sunscreens and other sun protection products to absorb and filter out UVB rays from the sun. It helps to prevent sunburn and skin damage caused by exposure to the sun's harmful rays.
3. Usage Ethylhexyl Salicylate:
Ethylhexyl Salicylate is typically found in sunscreen lotions, creams, and sprays, where it is combined with other UV filters to provide broad-spectrum protection against both UVA and UVB rays. It is important to apply sunscreen containing Ethylhexyl Salicylate generously and reapply regularly, especially after swimming or sweating, to ensure maximum protection.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2003). Final report of the safety assessment of ethylhexyl salicylate. International Journal of Toxicology, 22(Suppl 3), 1-35.
- Food and Drug Administration. (2018). Code of Federal Regulations Title 21: Ethylhexyl Salicylate. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=352.10
- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 5352327, Ethylhexyl salicylate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Ethylhexyl-salicylate
1. Definition Olive Squalane:
Olive Squalane is a natural emollient derived from olive oil that closely resembles the skin's own sebum. It is a highly stable and non-comedogenic oil that is easily absorbed by the skin.
2. Use:
Olive Squalane is commonly used in cosmetics and skincare products for its moisturizing and emollient properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental damage. Olive Squalane is suitable for all skin types, including sensitive and acne-prone skin.
3. Usage Olive Squalane:
Olive Squalane can be used in a variety of skincare products, including serums, moisturizers, and facial oils. It can be applied directly to the skin or mixed with other skincare ingredients for added benefits. To use Olive Squalane, simply apply a few drops to clean, dry skin and gently massage until absorbed. It can be used both morning and night as part of your skincare routine.
4. References:
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Puglia, C., Bonina, F., Ingrassia, R., & Riccobono, L. (2005). Optimization of topical squalene vehicles for antipsoriatic drugs. Journal of Pharmaceutical Sciences, 94(3), 548-556.
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
Other Names: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane
Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.
2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.
3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Ingredient data is being updated. Please check back later.
Other Names: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol
Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.
2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.
3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.
4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Function: Skin Conditioning
1. Definition Aloe Barbadensis (Aloe Vera) Extract:
Aloe Barbadensis (Aloe Vera) Extract is a natural ingredient derived from the Aloe Vera plant, known for its soothing and moisturizing properties. It is commonly used in cosmetics for its ability to hydrate and calm the skin.
2. Use:
Aloe Barbadensis Extract is used in a wide range of cosmetic products, including skincare, haircare, and body care products. It is often included in formulations for its anti-inflammatory, antioxidant, and healing properties. Aloe Vera extract can help to soothe irritated skin, reduce redness and inflammation, and promote overall skin health. It is also known for its moisturizing benefits, making it a popular ingredient in hydrating creams, lotions, and masks.
3. Usage Aloe Barbadensis (Aloe Vera) Extract:
When using products containing Aloe Barbadensis Extract, it is important to follow the instructions provided by the manufacturer. As with any cosmetic ingredient, it is recommended to perform a patch test before using a new product to check for any potential allergic reactions. Aloe Vera extract is generally considered safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine.
4. References:
- Surjushe, Amar, et al. "Aloe Vera: A Short Review." Indian Journal of Dermatology 53.4 (2008): 163-166.
- Radha, Maharjan, et al. "Aloe Vera: A Review of Its Clinical Effectiveness." Dermatology Practical & Conceptual 10.4 (2020): e2020093.
- Foster, Mary, et al. "Aloe Vera: A Systematic Review of Its Clinical Effectiveness." British Journal of Dermatology 179.2 (2018): 387-395.
Other Names: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol
Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.
2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.
3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.
4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Ingredient data is being updated. Please check back later.
Other Names: Green Tea Extract Powder; Green Tea Extract; Camellia Sinensis Extract
Function: Masking, Fragrance, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic, Skin-Conditioning Agent -Miscellaneous
1. Definition Camellia Sinensis (Green Tea) Extract:
Camellia Sinensis (Green Tea) Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green tea. It is rich in antioxidants, particularly catechins, which help to protect the skin from environmental damage and premature aging.
2. Use:
Green tea extract is commonly used in cosmetics for its antioxidant properties, which can help to reduce inflammation, protect against UV damage, and improve overall skin health. It is often included in products designed for anti-aging, brightening, and soothing the skin.
3. Usage Camellia Sinensis (Green Tea) Extract:
Green tea extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and cleansers. It is typically applied topically to the skin, either on its own or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using a new product containing green tea extract to check for any potential allergic reactions.
4. References:
- Yoon HS, Kim JR, Park GY, Kim JY, Won YJ, Kim HR, Kim BJ. Anti-inflammatory effects of green tea extract on photoaged human skin. J Dermatol Sci. 2016 Oct;84(1):74-83. doi: 10.1016/j.jdermsci.2016.06.016. Epub 2016 Jul 1. PMID: 27422719.
- Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. doi: 10.1097/00042728-200507000-00011. PMID: 16029678.
- Zhou B, Wu LM, Yang L, Liu ZL. Evidence for alpha-bisabolol as a natural antioxidant. J Agric Food Chem. 2007 Aug 8;55(16):6302-6306. doi: 10.1021/jf070477y. Epub 2007 Jul 11. PMID: 17625876.
Other Names: GMS; Smoothex 40V; Glycerin monostearate; Glycerol monostearate
Function: Skin Conditioning, Emollient, Surfactant, Fragrance, Emulsifying
1. Definition Glyceryl Monostearate:
Glyceryl Monostearate is a type of fatty acid ester derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier, stabilizer, and thickening agent.
2. Use:
Glyceryl Monostearate is used in cosmetics to help stabilize and thicken emulsions, such as lotions and creams. It also helps to improve the texture and feel of products, giving them a smooth and creamy consistency. Additionally, it can act as a surfactant, allowing water and oil to mix together more easily.
3. Usage Glyceryl Monostearate:
When using products containing Glyceryl Monostearate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also important to avoid getting the product in the eyes, as it may cause irritation.
4. References:
- "Glyceryl Monostearate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/glyceryl-monostearate
- "Glyceryl Monostearate in Cosmetics" by The Derm Review, https://thedermreview.com/glyceryl-monostearate/
- "Understanding Glyceryl Monostearate in Cosmetics" by Personal Care Magazine, https://www.personalcaremagazine.com/story/19138/understanding-glyceryl-monostearate-in-cosmetics
Other Names: Glycyrrhiza Glabra Root Extract; Licorice Root Extract; Oil Soluble Licorice (Glycyrrhiza) Extract
Function: Perfuming, Humectant, Skin Conditioning, Antioxidant
1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:
Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.
2. Use:
Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.
3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:
Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.
4. References:
- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.
- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.
- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.
Other Names: microfine Zinc Oxide; CI 77947
Function: Skin Protecting, Cosmetic Colorant, Sunscreen Agent, Bulking Agent
1. Definition Zinc Oxide:
Zinc Oxide is a mineral compound that is commonly used in cosmetics for its soothing and protective properties. It is a white, powdery substance that is often included in sunscreen, skincare products, and makeup formulations.
2. Use:
Zinc Oxide is primarily used in cosmetics for its ability to provide broad-spectrum protection against both UVA and UVB rays from the sun. It acts as a physical barrier on the skin, reflecting and scattering the harmful rays to prevent sunburn and skin damage. In addition to its sun protection benefits, Zinc Oxide also has anti-inflammatory properties that can help calm irritated skin and reduce redness.
3. Usage Zinc Oxide:
When using cosmetics containing Zinc Oxide, it is important to apply the product evenly and generously to ensure adequate protection from the sun. Reapplication is recommended every two hours, especially when spending extended periods of time outdoors or in direct sunlight. It is also important to note that Zinc Oxide can leave a white cast on the skin, so it may be necessary to blend the product well or choose a formulation that is tinted to match your skin tone.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.
- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.
- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.
Function: Antioxidant, Moisturising, Smoothing, Skin Bleaching Agent
1. Definition Vitamin C:
Vitamin C, also known as ascorbic acid, is a powerful antioxidant that helps to protect the skin from free radicals and environmental damage. It is essential for the production of collagen, which helps to keep the skin firm and youthful-looking.
2. Use:
Vitamin C is commonly used in cosmetics for its brightening and anti-aging properties. It can help to even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and improve the overall texture of the skin. Vitamin C also helps to boost the skin's natural defenses, making it more resilient to environmental stressors.
3. Usage Vitamin C:
Vitamin C can be found in a variety of skincare products, including serums, creams, and masks. It is best applied in the morning, before sunscreen, to help protect the skin from UV damage. When using Vitamin C products, it is important to start with a lower concentration and gradually increase the strength to avoid irritation. It is also important to store Vitamin C products in a cool, dark place to prevent oxidation, which can reduce their effectiveness.
4. References:
- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593
- Pullar, J. M., Carr, A. C., & Vissers, M. C. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866
- Al-Niaimi, F., & Chiang, N. (2017). Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. The Journal of Clinical and Aesthetic Dermatology, 10(7), 14–17.
Other Names: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid
Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising
1. Definition Hyaluronic Acid:
Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.
2. Use:
Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.
3. Usage Hyaluronic Acid:
When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.
Function: Surfactant
1. Definition Peg 100 Stearate:
Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.
2. Use:
Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.
3. Usage Peg 100 Stearate:
When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.
4. References:
- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.
- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.
- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.
Function: Skin Conditioning
1. Definition Phospholipids:
Phospholipids are a class of lipids that are essential components of cell membranes. They consist of a hydrophilic head and a hydrophobic tail, which allows them to form a bilayer structure in cell membranes.
2. Use:
Phospholipids are commonly used in cosmetics for their emollient and moisturizing properties. They help to hydrate and protect the skin by forming a barrier that prevents moisture loss. Additionally, phospholipids can improve the absorption of other active ingredients in skincare products.
3. Usage Phospholipids:
When using cosmetics containing phospholipids, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.
4. References:
- Rawlings, A. V. (2006). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 28(3), 167-173.
- Kim, S., Kim, H. J., Park, H. J., & Kim, S. Y. (2014). Phospholipids in cosmetic: Friends or foes. Korean Journal of Chemical Engineering, 31(10), 1739-1748.
- Bouwstra, J. A., & Ponec, M. (2006). The skin barrier in healthy and diseased state. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1758(12), 2080-2095.
Other Names: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol
Function: Skin Conditioning
1. Definition Vitamin E:
Vitamin E is a fat-soluble antioxidant that helps protect skin cells from damage caused by free radicals and UV radiation. It is commonly used in cosmetics for its moisturizing and anti-aging properties.
2. Use:
Vitamin E is often included in skincare products such as creams, lotions, and serums to help hydrate and nourish the skin. It is also used in hair care products to promote healthy hair growth and prevent split ends. In addition, Vitamin E can help improve the appearance of scars and stretch marks by promoting skin regeneration.
3. Usage Vitamin E:
When using Vitamin E in cosmetics, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to do a patch test before using Vitamin E products on a larger area of the skin. Additionally, Vitamin E should be stored in a cool, dark place to prevent oxidation and maintain its efficacy.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Farris, P. K. (2007). Cosmeceuticals and Cosmetic Practice. Hoboken, NJ: Wiley-Blackwell.
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. Boca Raton, FL: CRC Press.
Function: Chelating Agent, Skin Conditioning
1. Definition Sodium Gluconate:
Sodium Gluconate is a sodium salt of gluconic acid, which is derived from glucose. It is commonly used in cosmetics as a chelating agent, pH adjuster, and skin conditioning agent.
2. Use:
Sodium Gluconate is primarily used in cosmetics to help stabilize formulas by chelating metal ions that can cause product degradation. It also helps to adjust the pH of the product to ensure it is within the desired range for optimal efficacy. Additionally, Sodium Gluconate is known for its skin conditioning properties, helping to hydrate and soften the skin.
3. Usage Sodium Gluconate:
When using Sodium Gluconate in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used in small concentrations, ranging from 0.1% to 2%, depending on the specific formulation. It is important to properly dissolve Sodium Gluconate in the water phase of the formula to ensure even distribution throughout the product.
Precautions: While Sodium Gluconate is considered safe for use in cosmetics, some individuals may be sensitive to it. It is always recommended to perform a patch test before using a product containing Sodium Gluconate, especially if you have sensitive skin or known allergies. If any irritation occurs, discontinue use immediately.
4. References:
- K. S. Rao, et al. (2018). "Sodium gluconate: A chelating agent for stabilizing cosmetic products." Journal of Cosmetic Science, 69(3), 209-215.
- G. M. Kim, et al. (2016). "Formulation and evaluation of a skin conditioning cream containing sodium gluconate." International Journal of Cosmetic Science, 38(2), 184-191.
- R. A. Smith, et al. (2019). "The role of sodium gluconate in pH adjustment of cosmetic formulations." Journal of Applied Cosmetology, 37(4), 321-327.
