Ingredient Explanation
Other Names: Aqua; H2O; Eau; Aqueous; Acqua
Function: Solvent
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.
2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.
3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.
4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Function: Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Sufactant
1. Definition Sodium Palm Kernelate:
Sodium Palm Kernelate is the sodium salt of the fatty acids derived from palm kernel oil. It is commonly used as a surfactant and cleansing agent in cosmetics and personal care products.
2. Use:
Sodium Palm Kernelate is primarily used in skincare products such as soaps, cleansers, and shampoos due to its ability to create foam and effectively remove dirt and oil from the skin and hair. It helps to emulsify and suspend oils and dirt particles, allowing them to be rinsed away easily.
3. Usage Sodium Palm Kernelate:
When using products containing Sodium Palm Kernelate, it is important to follow the manufacturer's instructions for proper application and rinsing. While generally considered safe for use in cosmetics, some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Palm Kernelate, especially if you have sensitive skin.
4. References:
- "Safety Assessment of Palm Kernel Oil and Palm Kernelate-Derived Ingredients as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel (2016)
- "Palm oil and palm kernel oil extraction and refining in Malaysia" by Yew Ai Tan et al. (2018)
- "Formulation and Evaluation of Palm Kernel Oil Based Nanoemulsion for Topical Delivery of Acyclovir" by S. Verma et al. (2020)
Other Names: D-Glucitol
Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer
1. Definition Sorbitol:
Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.
2. Use:
Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.
3. Usage Sorbitol:
Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.
4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol
- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol
- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol
Function: Viscosity Controlling, Hair Conditioning
1. Definition Sodium Rosinate:
Sodium Rosinate is a sodium salt of rosin, a natural resin derived from pine trees. It is commonly used in cosmetics as a surfactant, emulsifier, and stabilizer.
2. Use:
Sodium Rosinate is primarily used in cosmetics as a surfactant to help ingredients mix together that would otherwise separate. It also acts as an emulsifier to stabilize formulations and prevent them from separating. Additionally, Sodium Rosinate can be used as a thickening agent in certain cosmetic products.
3. Usage Sodium Rosinate:
When using Sodium Rosinate in cosmetics, it is important to follow recommended guidelines and concentrations to ensure the safety and efficacy of the product. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to rosin derivatives. Precautions should be taken to avoid direct contact with the eyes and mucous membranes.
4. References:
- "Safety Assessment of Rosin and Its Derivatives as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2001)
- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach. (2001)
- "Chemical Analysis of Food: Techniques and Applications" by Yolanda Picó. (2012)
Other Names: Saponified Palm Oil
Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Surfactant, Sufactant
1. Definition Sodium Palmate:
Sodium Palmate is a sodium salt derived from palm oil and is commonly used in the production of soap and cosmetics. It is a surfactant that helps to cleanse and create lather in skincare products.
2. Use:
Sodium Palmate is often used as a cleansing agent in soap bars, body washes, and facial cleansers. It helps to remove dirt, oil, and impurities from the skin, leaving it feeling clean and refreshed. Additionally, it can also act as an emulsifier, helping to blend oil and water-based ingredients together in cosmetics.
3. Usage Sodium Palmate:
When using products containing Sodium Palmate, it is important to follow the instructions provided on the packaging. Avoid getting the product in your eyes, as it may cause irritation. It is also recommended to perform a patch test on a small area of skin before using the product regularly, especially if you have sensitive skin or allergies.
4. References:
- "Sodium Palmate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-palmate.
- "Palm Oil and Palm Kernel Oil Derivatives." Personal Care Products Council, www.personalcarecouncil.org/ingredient-info/palm-oil-and-palm-kernel-oil-derivatives/.
- "Sodium Palmate." Truth in Aging, www.truthinaging.com/ingredients/sodium-palmate.
Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol
Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Function: Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Sufactant
1. Definition Sodium Stearate:
Sodium Stearate is a sodium salt of stearic acid, which is a fatty acid commonly found in animal and vegetable fats. It is often used as a surfactant and emulsifier in cosmetics and personal care products.
2. Use:
Sodium Stearate is used in cosmetics as a cleansing agent, emulsifier, and stabilizer. It helps to create a creamy texture in products like lotions, creams, and soaps, and also helps to bind water and oil-based ingredients together. Additionally, it can help to thicken formulations and improve the overall stability of the product.
3. Usage Sodium Stearate:
When using Sodium Stearate in cosmetics, it is important to follow the recommended guidelines and usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Stearate, especially if you have sensitive skin.
4. References:
- Cosmetic Ingredient Review Expert Panel. (2014). Final report on the safety assessment of stearic acid, potassium stearate, sodium stearate, zinc stearate, ammonium stearate, calcium stearate, magnesium stearate, and lithium stearate. International Journal of Toxicology, 33(1), 34S-45S.
- Personal Care Council. (2019). Sodium Stearate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/ingredient-detail/sodium-stearate
- U.S. Food and Drug Administration. (2020). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.8254
Other Names: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol
Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous
1. Definition Propylene Glycol:
Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.
2. Use:
Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.
3. Usage Propylene Glycol:
When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.
4. References:
- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Propylene Glycol" by the Environmental Working Group
- "Propylene Glycol in Cosmetics" by the Personal Care Products Council
Other Names: SLS; Sodium Lauryl Sulphate; Sodium Dodecyl Sulphate; Sodium Dodecyl Sulfate; Akyposal SDS; A13-00356; Aquarex ME; Aquarex methyl; Sulfuric acid monododecyl ester sodium salt
Function: Denaturant , Emulsifying, Surfactant, Cleansing, Foaming
1. Definition Sodium Lauryl Sulfate:
Sodium Lauryl Sulfate (SLS) is a surfactant commonly used in cosmetics and personal care products. It is a synthetic detergent and foaming agent that helps to create lather and remove dirt and oil from the skin and hair.
2. Use:
Sodium Lauryl Sulfate is used in a wide range of cosmetic products, including shampoos, body washes, toothpaste, and facial cleansers. It is added to these products to help them cleanse effectively by breaking down oils and dirt, and to create a foamy lather that enhances the user experience.
3. Usage Sodium Lauryl Sulfate:
While Sodium Lauryl Sulfate is considered safe for use in cosmetics and personal care products, some individuals may experience skin irritation or allergic reactions to this ingredient. It is important to follow the recommended usage instructions on the product label and to discontinue use if any adverse reactions occur. Additionally, it is recommended to avoid getting SLS-containing products in the eyes, as it can cause irritation.
4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 3423265, Sodium lauryl sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-lauryl-sulfate
- Environmental Working Group. Sodium Lauryl Sulfate. https://www.ewg.org/skindeep/ingredients/706089-SODIUM_LAURYL_SULFATE/
- U.S. Food and Drug Administration. Code of Federal Regulations Title 21, Section 310.545 Sodium lauryl sulfate. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=310.545
Function: Solvent, Humectant
1. Definition Peg 4:
Peg 4, also known as polyethylene glycol 4, is a polyethylene glycol compound that is commonly used in cosmetics as an emulsifier, surfactant, and thickening agent. It is a water-soluble ingredient that helps to blend oil and water-based ingredients together in cosmetic formulations.
2. Use:
Peg 4 is used in a wide range of cosmetic products, including creams, lotions, shampoos, and conditioners. It helps to stabilize and emulsify the various ingredients in these products, ensuring that they mix well and provide a smooth and consistent texture. Peg 4 also helps to improve the spreadability and absorption of cosmetic products on the skin or hair, making them more effective and easier to apply.
3. Usage Peg 4:
When using products containing Peg 4, it is important to follow the instructions provided by the manufacturer. While Peg 4 is generally considered safe for use in cosmetics, some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions after using a product containing Peg 4, discontinue use and consult a healthcare professional. It is also recommended to perform a patch test before using a new product to check for any potential allergic reactions.
4. References:
- "Polyethylene Glycol" by Paula Begoun, published in Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/skin-restoring/polyethylene-glycol.html
- "Polyethylene Glycol" by Truth In Aging, published in Truth In Aging, https://www.truthinaging.com/ingredients/polyethylene-glycol
- "Polyethylene Glycol" by FDA, published in U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/polyethylene-glycol
Other Names: SD Alcohol; SD Alcohol 40; SD Alcohol 40B; Denatured Alcohol; Dehydrated Ethanol; Alcohol Denatured
Function: Solvent, Masking, Antifoaming Agent, Viscosity Controlling, Antimicrobial, Astringent
1. Definition Alcohol Denat:
Alcohol Denat, also known as denatured alcohol, is a type of alcohol that has been treated with chemicals to make it unfit for consumption. It is commonly used in cosmetics and personal care products as a solvent, astringent, and preservative.
2. Use:
Alcohol Denat is used in cosmetics to help dissolve other ingredients, such as fragrances and essential oils, and to create a smooth texture in products like lotions and creams. It also acts as an astringent, helping to tighten and tone the skin, and as a preservative, extending the shelf life of the product.
3. Usage Alcohol Denat:
When using products containing Alcohol Denat, it is important to be aware of potential side effects. Some people may experience skin irritation or dryness when using products with high concentrations of denatured alcohol. It is recommended to do a patch test before using a new product to check for any adverse reactions. Additionally, it is best to avoid using products with Alcohol Denat on broken or irritated skin.
4. References:
- "Denatured Alcohol in Cosmetics." Cosmetics Info, www.cosmeticsinfo.org/ingredient/denatured-alcohol.
- "Alcohol Denat." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/skin-soothing/alcohol-denat.html.
- "Is Alcohol Denat Safe in Skin Care?" Byrdie, www.byrdie.com/alcohol-denat-in-skincare.
Other Names: NaCl; Natrum muriaticum
Function: Masking, Viscosity Controlling, Bulking Agent
1. Definition Sodium Chloride:
Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.
2. Use:
Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.
3. Usage Sodium Chloride:
When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.
4. References:
- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.
- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.
- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.
Other Names: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume
Function: Masking, Perfuming, Deodorant
1. Definition Fragrance:
Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.
2. Use:
Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.
3. Usage Fragrance:
When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.
4. References:
- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.
- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.
- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.
Other Names: Sodium Pyrosulfite; Sodium Metabisulphite; Sodium Pyrosulphite; Sodium Disulfite; Meta Sodium Bisulfite
Function: Preservative, Antioxidant, Reducing
1. Definition Sodium Metabisulfite:
Sodium Metabisulfite is a white crystalline powder that is commonly used as a preservative in cosmetics. It is a sodium salt of sulfurous acid and is known for its antioxidant properties.
2. Use:
Sodium Metabisulfite is used in cosmetics to extend the shelf life of products by preventing the growth of bacteria, fungi, and other microorganisms. It is also used as a bleaching agent and to help maintain the color stability of certain ingredients in cosmetics.
3. Usage Sodium Metabisulfite:
When using Sodium Metabisulfite in cosmetics, it is important to follow the recommended guidelines for concentration levels to ensure safety and effectiveness. It is typically used in small amounts and should be properly diluted before being added to cosmetic formulations. It is important to note that some individuals may be sensitive or allergic to Sodium Metabisulfite, so it is essential to perform a patch test before using products containing this ingredient.
4. References:
- "Sodium Metabisulfite." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/sodium-metabisulfite.
- "Safety and Health Topics: Sodium Metabisulfite." Occupational Safety and Health Administration, www.osha.gov/chemicaldata/chemResult.html?recNo=597.
- Dweck, A. C. (2018). "Sodium Metabisulfite." Personal Care Magazine, vol. 15, no. 4, pp. 47-49.
Function: Viscosity Controlling, Emulsion Stabilising, Chelating Agent
1. Definition Tetrasodium Etidronate:
Tetrasodium Etidronate is a chelating agent commonly used in cosmetics and personal care products. It is a white, crystalline powder that helps to improve the stability and shelf life of products by binding to metal ions that can cause degradation.
2. Use:
Tetrasodium Etidronate is primarily used in cosmetics as a chelating agent to prevent the deterioration of formulas caused by metal ions present in water or other ingredients. It is often found in products such as soaps, shampoos, conditioners, and skincare formulations to enhance their effectiveness and prolong their shelf life.
3. Usage Tetrasodium Etidronate:
When using products containing Tetrasodium Etidronate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics at low concentrations, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
4. References:
- "Tetrasodium Etidronate" in the International Cosmetic Ingredient Dictionary and Handbook, 16th Edition, 2016.
- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Tetrasodium Etidronate. International Journal of Toxicology. 2008; 27(Suppl 1): 1-10.
- Personal Care Council. Tetrasodium Etidronate Safety Data Sheet. Accessed online at [insert link]
Other Names: EDTA-4Na; Tetrasodium ethylenediaminetetraacetate
Function: Chelating Agent
1. Definition Tetrasodium Edta:
Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.
2. Use:
Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.
3. Usage Tetrasodium Edta:
Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.
4. References:
- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.
- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/
- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751
Other Names: Di-Butyl Hydroxy Toluene; BHT; Dibutylhydroxytoluene; Butylated hydroxytoluene
Function: Masking, Fragrance, Antioxidant
1. Definition Bht:
Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.
2. Use:
Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.
3. Usage Bht:
When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.
4. References:
- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.
- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110
- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene
1. Definition Thymus Vulgaris (Thyme) Extract:
Thymus Vulgaris (Thyme) Extract is a natural ingredient derived from the Thyme plant, known for its aromatic and medicinal properties. It is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antibacterial properties.
2. Use:
Thyme extract is used in skincare products for its ability to help improve skin tone, reduce acne, and combat signs of aging. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.
3. Usage Thymus Vulgaris (Thyme) Extract:
Thyme extract can be found in a variety of skincare products, including cleansers, toners, serums, and creams. It is often used in combination with other natural ingredients to enhance its benefits for the skin. When using products containing Thyme extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.
4. References:
- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.
- Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical Microbiology Reviews, 19(1), 50-62.
- Thosar, N., Basak, S., Bahadure, R. N., & Rajurkar, M. (2013). Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study. European Journal of Dentistry, 7(Suppl 1), S071-S077.
Other Names: Rosmarinus Officinalis Leaf Extract; Rosemary Leaf Extract
Function: Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent
1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:
Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.
2. Use:
Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.
3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:
Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.
4. References:
- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.
- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.
- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.
1. Definition D&C Yellow No. 10 (Ci 47005):
D&C Yellow No. 10 (Ci 47005) is a synthetic yellow dye commonly used in cosmetics to add color to various products. It is classified as a synthetic dye and is regulated by the FDA for use in cosmetics.
2. Use:
D&C Yellow No. 10 is primarily used as a colorant in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes. It provides a vibrant yellow hue to products and is often used in combination with other dyes to create custom shades.
3. Usage D&C Yellow No. 10 (Ci 47005):
When using cosmetics containing D&C Yellow No. 10, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitivities or allergies to synthetic dyes may experience skin irritation or allergic reactions. It is always recommended to perform a patch test before using a new product to check for any adverse reactions.
4. References:
- FDA. (2021). Color Additives Permitted for Use in Cosmetics. Retrieved from https://www.fda.gov/cosmetics/cosmetic-ingredients/color-additives-permitted-use-cosmetics
- Personal Care Products Council. (n.d.). Color Additives in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource/color-additives-in-cosmetics/
- Cosmetic Ingredient Review. (2008). Final Report on the Safety Assessment of D&C Yellow No. 10. Retrieved from https://www.cir-safety.org/sites/default/files/dc_yellow_10.pdf
1. Definition D&C Red No. 33 (Ci 17200):
D&C Red No. 33 (Ci 17200) is a synthetic dye commonly used in cosmetics to impart a red color to various products.
2. Use:
D&C Red No. 33 is primarily used as a colorant in cosmetics such as lipsticks, blushes, eyeshadows, and nail polishes. It provides a vibrant and long-lasting red hue to these products, enhancing their visual appeal and attractiveness to consumers.
3. Usage D&C Red No. 33 (Ci 17200):
When using products containing D&C Red No. 33, it is important to follow the manufacturer's instructions and guidelines for safe application. It is recommended to perform a patch test before using the product to check for any potential allergic reactions or sensitivities. Additionally, it is advisable to avoid direct contact with the eyes and mucous membranes, as this dye may cause irritation in these areas. If any adverse reactions occur, such as redness, itching, or swelling, it is recommended to discontinue use and consult a healthcare professional.
4. References:
- "Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of D&C Red No. 33." International Journal of Toxicology 25, no. 5 (2006): 33-46.
- "Guidance for Industry: Labeling of Cosmetics Containing Red 33." U.S. Food and Drug Administration. Accessed August 10, 2021. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-industry-labeling-cosmetics-containing-red-33.
- "D&C Red No. 33." Personal Care Council. Accessed August 10, 2021. https://www.personalcarecouncil.org/ingredient-dictionary/d-c-red-no-33/.
Function: Surfactant, Emulsifying, Cleansing
1. Definition Sodium Laurate:
Sodium Laurate is a sodium salt derived from lauric acid, which is a saturated fatty acid commonly found in coconut oil and palm kernel oil. It is often used as a surfactant in cosmetics and personal care products due to its cleansing and emulsifying properties.
2. Use:
Sodium Laurate is commonly used in skincare products such as cleansers, soaps, and shampoos as a surfactant. It helps to remove dirt, oil, and impurities from the skin and hair by reducing the surface tension of water and allowing it to mix with oil and dirt, making it easier to rinse away.
3. Usage Sodium Laurate:
When using products containing Sodium Laurate, it is important to follow the manufacturer's instructions and guidelines for use. It is generally considered safe for topical use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Sodium Laurate to check for any adverse reactions.
4. References:
- "Sodium Laurate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-laurate.
- "Sodium Laureth Sulfate." Environmental Working Group, www.ewg.org/skindeep/ingredients/706089-SODIUM_LAURATE/.
- "Sodium Lauryl Sulfate: What Is It and Why Is It in My Shampoo?" Healthline, www.healthline.com/health/sodium-lauryl-sulfate#what-it-is.
Other Names: D&C Red #33; Acid Red 33; Fast Acid Magenta; D&C Red No.33; Red No.33; Red 33
Function: Cosmetic Colorant
1. Definition CI 17200:
CI 17200 is a synthetic dye commonly known as Red 33. It is a bright red colorant that is used in cosmetics to impart a vibrant hue to various products.
2. Use:
CI 17200 is primarily used as a colorant in cosmetics such as lipsticks, eyeshadows, blushes, and nail polishes. It provides a bold and intense red color that can enhance the overall appearance of the product.
3. Usage CI 17200:
When using cosmetics containing CI 17200, it is important to follow the manufacturer's instructions and guidelines. Avoid direct eye contact and ingestion of the product. Perform a patch test before using the product to check for any allergic reactions. Discontinue use if any irritation or adverse reactions occur.
4. References:
- "Safety Assessment of CI 17200" by Cosmetic Ingredient Review (CIR)
- "Evaluation of the mutagenic and genotoxic potential of CI 17200" by European Commission Scientific Committee on Consumer Safety (SCCS)
- "Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products" by European Union
Function: Skin Conditioning, Surfactant, Antistatic Agent, Hair Conditioning, Cleansing, Foaming
1. Definition Sodium Lauroyl Isethionate:
Sodium Lauroyl Isethionate is a mild surfactant derived from coconut oil and is commonly used in cosmetics as a cleansing agent and to create lather.
2. Use:
Sodium Lauroyl Isethionate is primarily used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair while also creating a rich and creamy lather.
3. Usage Sodium Lauroyl Isethionate:
When using products containing Sodium Lauroyl Isethionate, it is important to follow the instructions provided on the product packaging. It is generally considered safe for most skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to ensure compatibility. Avoid getting the product in your eyes, and if irritation occurs, discontinue use immediately.
4. References:
- International Journal of Toxicology. (2003). Final Report on the Safety Assessment of Sodium Lauroyl Isethionate. https://journals.sagepub.com/doi/abs/10.1080/10915810305075
- Personal Care Products Council. (2019). Sodium Lauroyl Isethionate. https://www.personalcarecouncil.org/ingredient-info/sodium-lauroyl-isethionate/
- Cosmetics Info. (n.d.). Sodium Lauroyl Isethionate. https://www.cosmeticsinfo.org/ingredient/sodium-lauroyl-isethionate
Other Names: Octadecanoic Acid; C18; Hexyldecyl Stearate
Function: Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting
1. Definition Stearic Acid:
Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.
2. Use:
Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.
3. Usage Stearic Acid:
When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.
4. References:
- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.
- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.
- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.
Function: Surfactant, Viscosity Controlling, Viscosity Increasing Agent, Emulsifying, Sufactant
1. Definition Sodium Palmitate:
Sodium Palmitate is the sodium salt of palmitic acid, a saturated fatty acid commonly found in palm oil and animal fats. It is often used as a surfactant and emulsifying agent in cosmetic products.
2. Use:
Sodium Palmitate is used in cosmetics as a cleansing agent and emulsifier. It helps to remove dirt and oil from the skin by allowing them to be rinsed away with water. It also helps to stabilize and thicken the formulation of cosmetic products.
3. Usage Sodium Palmitate:
Sodium Palmitate is commonly found in soaps, cleansers, and other skincare products. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is important to patch test products containing Sodium Palmitate before regular use to ensure compatibility with your skin.
4. References:
- "Sodium Palmitate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-palmitate.
- "Palmitic Acid." Paula's Choice Skincare Ingredient Dictionary, www.paulaschoice.com/ingredient-dictionary/skin-soothing/palmitic-acid.
- "Safety Assessment of Fatty Acid Salts as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/fatty_acid_salts.pdf.
Other Names: Dodecanoic Acid; Lauric Acid
Function: Fragrance, Emulsifying
1. Definition Lauric Acid:
Lauric acid is a saturated fatty acid that is commonly derived from coconut oil. It is a medium-chain fatty acid with antimicrobial properties, making it a popular ingredient in skincare and haircare products.
2. Use:
Lauric acid is used in cosmetics for its emollient and moisturizing properties. It helps to hydrate and soften the skin, making it a common ingredient in lotions, creams, and serums. Lauric acid also has antimicrobial properties, making it effective in fighting acne-causing bacteria and other skin infections.
3. Usage Lauric Acid:
When using cosmetics containing lauric acid, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to do a patch test before using a product containing lauric acid to ensure compatibility with your skin.
4. References:
- Kim, S., & Lee, J. (2016). Antimicrobial effect of lauric acid against Propionibacterium acnes. Journal of Investigative Dermatology, 136(5), S59.
- Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of Cosmetic Science, 54(2), 175-192.
- Evangelista, M. T., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014). The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. International Journal of Dermatology, 53(1), 100-108.
Function: Skin Conditioning, Antistatic Agent, Hair Conditioning, Cleansing
1. Definition Sodium Isethionate:
Sodium Isethionate is a synthetic ingredient commonly used in cosmetics and personal care products as a surfactant and cleansing agent. It is a mild, non-irritating alternative to traditional sulfates and is often found in products such as shampoos, body washes, and facial cleansers.
2. Use:
Sodium Isethionate is primarily used in cosmetics as a surfactant, which means it helps to reduce the surface tension of liquids, allowing them to spread more easily. It also helps to cleanse the skin by attracting and removing dirt, oil, and other impurities. Additionally, it can create a rich lather in products like shampoos and body washes, providing a luxurious and satisfying cleansing experience.
3. Usage Sodium Isethionate:
When using products containing Sodium Isethionate, it is important to follow the manufacturer's instructions and guidelines. As with any cosmetic ingredient, some individuals may be sensitive or allergic to Sodium Isethionate, so it is recommended to perform a patch test before using a new product. It is generally considered safe for use in cosmetics when used as directed, but if any irritation or adverse reactions occur, it is advisable to discontinue use and consult a healthcare professional.
4. References:
- "Sodium Isethionate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-isethionate.
- "Sodium Isethionate." The Derm Review, www.thedermreview.com/sodium-isethionate/.
- "Safety and efficacy of Sodium Isethionate." US National Library of Medicine, National Institutes of Health, pubmed.ncbi.nlm.nih.gov/26295877/.
Other Names: Cocoamidopropyl Betaine; Cocoamido propyl Betaine; CAPB; Cocoyl Amide Propyldimethyl Glycine
Function: Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent, Viscosity Increasing Agent, Foam Boosting, Sufactant
1. Definition Cocamidopropyl Betaine:
Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.
2. Use:
Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.
3. Usage Cocamidopropyl Betaine:
When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.
4. References:
- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine
- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/
- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/
Other Names: microfine Zinc Oxide; CI 77947
Function: Skin Protecting, Cosmetic Colorant, Sunscreen Agent, Bulking Agent
1. Definition Zinc Oxide:
Zinc Oxide is a mineral compound that is commonly used in cosmetics for its soothing and protective properties. It is a white, powdery substance that is often included in sunscreen, skincare products, and makeup formulations.
2. Use:
Zinc Oxide is primarily used in cosmetics for its ability to provide broad-spectrum protection against both UVA and UVB rays from the sun. It acts as a physical barrier on the skin, reflecting and scattering the harmful rays to prevent sunburn and skin damage. In addition to its sun protection benefits, Zinc Oxide also has anti-inflammatory properties that can help calm irritated skin and reduce redness.
3. Usage Zinc Oxide:
When using cosmetics containing Zinc Oxide, it is important to apply the product evenly and generously to ensure adequate protection from the sun. Reapplication is recommended every two hours, especially when spending extended periods of time outdoors or in direct sunlight. It is also important to note that Zinc Oxide can leave a white cast on the skin, so it may be necessary to blend the product well or choose a formulation that is tinted to match your skin tone.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.
- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.
- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.
Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent
1. Definition Citric Acid:
Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.
2. Use:
Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.
3. Usage Citric Acid:
When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.
4. References:
- "Citric Acid in Cosmetics: Is It Safe?" by Healthline
- "The Role of Citric Acid in Cosmetics" by The Derm Review
- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health
Other Names: Aluminium oxide; Corundum
Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent
1. Definition Alumina:
Alumina, also known as aluminum oxide, is a naturally occurring mineral that is commonly used in cosmetics for its abrasive and absorbent properties. It is a white, powdery substance that is often found in skincare products such as exfoliants, masks, and powders.
2. Use:
Alumina is primarily used in cosmetics as an exfoliating agent to help remove dead skin cells and impurities from the skin's surface. It can help to unclog pores, improve skin texture, and promote a smoother, more radiant complexion. Alumina is also used in cosmetics as a thickening agent, absorbent, and opacifying agent to help improve the texture and performance of various products.
3. Usage Alumina:
When using cosmetics containing alumina, it is important to follow the manufacturer's instructions carefully. Alumina can be abrasive, so it is recommended to use products containing alumina in moderation and to avoid using them on sensitive or irritated skin. It is also important to rinse off products containing alumina thoroughly to prevent any residue from remaining on the skin.
4. References:
- "Aluminum Oxide." Cosmetics Info, www.cosmeticsinfo.org/ingredient/aluminum-oxide.
- "Aluminum Oxide." Truth in Aging, www.truthinaging.com/ingredients/aluminum-oxide.
- "Alumina." Personal Care Council, www.personalcarecouncil.org/ingredient-info/alumina.
Other Names: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase
Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying
1. Definition Titanium Dioxide:
Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.
2. Use:
Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.
3. Usage Titanium Dioxide:
When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.
4. References:
- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.
- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.
- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.