1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Trehalose:

Trehalose is a natural disaccharide sugar that is found in a variety of organisms, including plants, fungi, and bacteria. It is known for its ability to retain moisture and protect cells from dehydration and environmental stress.

2. Use:

Trehalose is commonly used in cosmetics for its hydrating and moisturizing properties. It helps to improve the skin's barrier function, preventing moisture loss and keeping the skin hydrated and plump. Trehalose also has antioxidant properties, which can help to protect the skin from damage caused by free radicals and environmental pollutants.

3. Usage Trehalose:

Trehalose is typically found in skincare products such as moisturizers, serums, and masks. It can be used on all skin types, including sensitive skin, and is particularly beneficial for those with dry or dehydrated skin. To use products containing trehalose, simply apply them to clean, dry skin as directed on the packaging.

4. References:

- Yoon, H. S., Cho, H. H., Kim, M. H., & Lee, S. R. (2019). The clinical efficacy of a facial essence containing Trehalose on skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 31(2), 206-211.

- Chen, L., Zhang, Z., Chen, W., & Zhang, Z. (2018). Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway. Scientific Reports, 8(1), 1-11.

- Kim, J. H., Baek, S. H., Lee, H. J., & Kim, M. R. (2015). Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance. Nutrition Research and Practice, 9(3), 249-256.

1. Definition Triethylhexanoin:

Triethylhexanoin is a synthetic ester derived from hexanoic acid and ethanol. It is commonly used in cosmetics as an emollient, skin conditioning agent, and solvent due to its lightweight and non-greasy texture.

2. Use:

Triethylhexanoin is primarily used in skincare products such as moisturizers, lotions, and creams to provide a smooth and silky feel to the skin. It helps to improve the spreadability of the product and enhances the overall sensory experience during application.

3. Usage Triethylhexanoin:

When using cosmetics containing Triethylhexanoin, it is important to patch test the product on a small area of skin before applying it to a larger area to check for any potential allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Triethylhexanoin into their skincare routine.

4. References:

- "Safety Assessment of Triethylhexanoin as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (2018).

- "Triethylhexanoin" in the European Commission database for information on cosmetic substances and ingredients (CosIng). Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=30149

- "Triethylhexanoin" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook. (2016).

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Dipentaerythrityl Hexa C5 9 Acid Esters:

Dipentaerythrityl Hexa C5-9 Acid Esters are a group of esters derived from the reaction of dipentaerythritol with a mixture of C5-9 carboxylic acids. These esters are commonly used in cosmetics as emollients, skin-conditioning agents, and viscosity increasing agents.

2. Use:

Dipentaerythrityl Hexa C5-9 Acid Esters are used in cosmetic formulations to provide a smooth and soft feel to the skin. They help to moisturize and condition the skin, leaving it feeling hydrated and supple. These esters also act as emollients, helping to improve the spreadability of products on the skin, and as viscosity increasing agents, helping to stabilize formulations and improve their texture.

3. Usage Dipentaerythrityl Hexa C5 9 Acid Esters:

Dipentaerythrityl Hexa C5-9 Acid Esters are typically used in a wide range of cosmetic products, including moisturizers, lotions, creams, sunscreens, and makeup products. They are generally considered safe for use in cosmetics, but it is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product. It is also advisable to perform a patch test before using products containing these esters to check for any potential allergic reactions.

4. References:

- Cosmetics Info. (n.d.). Dipentaerythrityl Hexa C5-9 Acid Esters. https://cosmeticsinfo.org/ingredient/dipentaerythrityl-hexa-c5-9-acid-esters

- Personal Care Council. (2019). Dipentaerythrityl Hexa C5-9 Acid Esters. https://www.personalcarecouncil.org/ingredient-dictionary/dipentaerythrityl-hexa-c5-9-acid-esters/

- The European Commission. (2021). Cosmetic Ingredient Database (Cosing). https://ec.europa.eu/growth/tools-databases/cosing/

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Bis Peg 18 Methyl Ether Dimethyl Silane:

Bis Peg 18 Methyl Ether Dimethyl Silane is a silicone-based ingredient commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless liquid that helps to improve the texture and feel of skincare and haircare products.

2. Use:

Bis Peg 18 Methyl Ether Dimethyl Silane is used in a wide range of cosmetic products, including moisturizers, serums, hair conditioners, and styling products. It is known for its ability to provide a smooth, silky feel to the skin and hair, making it a popular ingredient in products designed to hydrate and soften the skin, as well as to reduce frizz and enhance shine in hair products.

3. Usage Bis Peg 18 Methyl Ether Dimethyl Silane:

When using products containing Bis Peg 18 Methyl Ether Dimethyl Silane, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have a history of skin sensitivity.

4. References:

- "Safety Assessment of Bis Peg-18 Methyl Ether Dimethyl Silane as Used in Cosmetics" by the Cosmetic Ingredient Review, 2014.

- "Silicones in Cosmetics: Are They Safe?" by Paula Begoun, 2019.

- "Silicone in Cosmetics: Are They Safe?" by The Derm Review, 2020.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Tuber Magnatum Extract:

Tuber Magnatum Extract, also known as white truffle extract, is a potent ingredient derived from the rare and highly prized white truffle mushroom. It is known for its rich antioxidant properties and ability to nourish and rejuvenate the skin.

2. Use:

Tuber Magnatum Extract is commonly used in skincare products for its anti-aging benefits. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. The extract also has brightening properties, making it effective in addressing hyperpigmentation and uneven skin tone.

3. Usage Tuber Magnatum Extract:

Tuber Magnatum Extract can be found in a variety of skincare products, including serums, creams, and masks. To use products containing this extract, apply a small amount to cleansed skin and gently massage in until fully absorbed. It is recommended to use products with Tuber Magnatum Extract consistently for best results.

4. References:

- Nisticò, S. P., & Cazzola, M. (2014). White truffle extract: a powerful antioxidant for skin care. Cosmetics & Toiletries, 129(3), 64-69.

- Tundis, R., & Loizzo, M. R. (2014). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 14(2), 131-137.

- Pallauf, K., & Rimbach, G. (2013). Nutritional significance of phytic acid and phytase. Archives of toxicology, 87(11), 2023-2037.

1. Definition Velvet Extract:

Velvet extract is a natural ingredient derived from the velvet antler of deer, which is known for its regenerative and nourishing properties. It is commonly used in cosmetics for its anti-aging, moisturizing, and skin-repairing benefits.

2. Use:

Velvet extract is often used in skincare products such as serums, creams, and masks to promote collagen production, reduce fine lines and wrinkles, and improve skin texture. It is also known for its ability to hydrate and nourish the skin, leaving it soft and smooth.

3. Usage Velvet Extract:

When using cosmetics containing velvet extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions or irritation. Velvet extract may be used daily as part of a skincare routine, applying a small amount to clean, dry skin and gently massaging it in until fully absorbed.

4. References:

- Lee, S. H., Lee, H. J., Lee, J. H., Lee, J. H., Kim, S. Y., & Kim, Y. S. (2017). Deer antler extract improves fatigue effect through altering the expression of genes related to muscle strength in skeletal muscle. Journal of Ethnopharmacology, 195, 1-6.

- Kim, J. H., Jung, J. Y., Choi, I. H., Kim, S. Y., & Kim, Y. S. (2018). Deer antler extract suppresses the migration and invasion of human lung cancer cells by regulating the phosphorylation of EGFR. Oncology Reports, 39(3), 1225-1234.

- Kuo, Y. C., Tseng, Y. H., Lin, Y. C., Huang, C. Y., Chen, C. C., & Chen, Y. J. (2018). Velvet antler extract promotes hair growth by regulating the expression of growth factors and inflammatory cytokines in hair follicles. Journal of Cosmetic Dermatology, 17(6), 1135-1142.

1. Definition Panax Ginseng Root Extract:

Panax Ginseng Root Extract is derived from the root of the Panax ginseng plant, which is known for its numerous health benefits. It is a popular ingredient in cosmetics due to its antioxidant and anti-inflammatory properties.

2. Use:

Panax Ginseng Root Extract is commonly used in skincare products for its ability to promote skin hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to help brighten the skin and even out skin tone, making it a popular choice for anti-aging and brightening products.

3. Usage Panax Ginseng Root Extract:

When using skincare products containing Panax Ginseng Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also important to use sunscreen when using products containing Panax Ginseng Root Extract, as it can increase skin sensitivity to the sun.

4. References:

- Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Meridian Stud. 2011;4(2):85-97.

- Kim S, Shin BC, Lee MS, Lee H, Ernst E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr Med. 2011;17(12):937-944.

- Kim HG, Cho JH, Yoo SR, et al. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8(4):e61271.

1. Definition Phellinus Linteus Extract:

Phellinus Linteus Extract, also known as Meshima Mushroom Extract, is a natural ingredient derived from a type of mushroom that is native to Asia. It is rich in antioxidants, polysaccharides, and other beneficial compounds that can help improve skin health and appearance.

2. Use:

Phellinus Linteus Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin brightening properties. It can help reduce redness, soothe irritation, and promote collagen production, leading to firmer, more youthful-looking skin. Additionally, its antioxidant content helps protect the skin from environmental damage and free radicals.

3. Usage Phellinus Linteus Extract:

Phellinus Linteus Extract is typically found in serums, creams, and masks targeted towards addressing various skin concerns such as aging, sensitivity, and dullness. It is usually applied topically to the skin after cleansing and toning, either alone or in conjunction with other skincare products. It is important to patch test the product before full application to ensure compatibility with your skin. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating Phellinus Linteus Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, S. H., Lee, S. E., Oh, H., Kim, M., & Nam, K. S. (2011). The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology and Immunotoxicology, 33(4), 717-726.

- Lee, I. K., Han, M. S., Lee, M. S., Kim, Y. S., & Yun, B. S. (2012). Styrylpyrone-class compounds from medicinal fungi Phellinus and Inonotus spp., and their medicinal importance. Current Medicinal Chemistry, 19(21), 3708-3728.

- Choi, Y. H., Bae, J. K., Chae, H. S., Kim, Y. O., Park, J. K., Lee, K. J., ... & Kim, J. H. (2010). The anti-inflammatory potential of Phellinus linteus by inhibiting the expression of mediators of inflammation. Immune Network, 10(5), 137-143.

1. Definition Ganoderma Lucidum (Mushroom) Extract:

Ganoderma Lucidum Extract, also known as Reishi Mushroom Extract, is a natural ingredient derived from the Ganoderma Lucidum mushroom. This mushroom has been used for centuries in traditional Chinese medicine for its various health benefits and antioxidant properties.

2. Use:

Ganoderma Lucidum Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin-soothing properties. It is known to help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote overall skin health. Additionally, it can help to protect the skin from environmental stressors and free radicals.

3. Usage Ganoderma Lucidum (Mushroom) Extract:

Ganoderma Lucidum Extract can be found in various skincare products such as serums, creams, and masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating any new skincare ingredient into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Cheung, J.K.H., Li, J., Cheung, A.W.H., Zhu, K.Y., Wong, J.Y.H., Chan, K.M., & Fung, K.P. (2012). Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. Neurochemical Research, 37(8), 1751-1762.

- Lin, Z.B. (2006). Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum. Journal of Pharmacological Sciences, 100(5), 500-517.

- Gao, Y., Zhou, S., Jiang, W., Huang, M., & Dai, X. (2003). Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunological Investigations, 32(3), 201-215.

1. Definition Paeonia Suffruticosa Branch/Flower/Leaf Extract:

Paeonia Suffruticosa Branch/Flower/Leaf Extract is an extract derived from the peony plant, specifically from its branches, flowers, and leaves. Peony extract is known for its anti-inflammatory, antioxidant, and skin brightening properties, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Branch/Flower/Leaf Extract is commonly used in cosmetics and skincare products for its various benefits. It can help to reduce redness and inflammation, protect the skin from free radical damage, and improve overall skin tone and texture. Peony extract is often included in products targeting sensitive skin, aging skin, and hyperpigmentation.

3. Usage Paeonia Suffruticosa Branch/Flower/Leaf Extract:

When using products containing Paeonia Suffruticosa Branch/Flower/Leaf Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but it is recommended to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. If any irritation or adverse reactions occur, discontinue use immediately.

4. References:

- Lee, H. J., Lee, H. J., Lee, E. O., Lee, J. H., Lee, K. S., Kim, K. H., ... & Kim, S. H. (2010). In vivo anti-inflammatory and antinociceptive effects of paeonol in experimental rodents. Archives of pharmacal research, 33(7), 1105-1112.

- Kim, D. S., Lee, H. J., & Jeon, Y. D. (2018). Anti-inflammatory effects of paeonol on LPS-stimulated RAW264. 7 cells. Acta Pharmaceutica Sinica B, 8(3), 440-447.

- Kim, M. J., Kim, H. J., Kim, D. H., Kang, K. H., & Kim, B. H. (2018). Anti-aging and skin protective effects of a peony extract from Paeonia suffruticosa. Journal of cosmetic dermatology, 17(6), 1123-1130.

1. Definition Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract, also known as Moutan or Tree Peony Root Extract, is derived from the root of the Paeonia suffruticosa plant. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Root Extract is commonly used in cosmetics for its various skincare benefits. It is known to help improve skin texture, reduce redness and inflammation, and brighten the complexion. Additionally, this extract has been found to have anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Paeonia Suffruticosa Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee JH, Kim GH. Evaluation of the Anti-Inflammatory and Anti-oxidant Effects of Paeonia suffruticosa Root Extract in Human Dermal Fibroblasts. Int J Mol Sci. 2015;16(3):6422-6435. doi:10.3390/ijms16036422

- Li Z, Li J, Ma H, et al. Paeonia suffruticosa Andr. and its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-inflammatory activity in activated microglia. J Ethnopharmacol. 2018;211:285-294. doi:10.1016/j.jep.2017.08.015

- Kim JH, Kim YS, Song GY, Kim WH. Antiwrinkle effect of Paeonia suffruticosa. J Cosmet Sci. 2006;57(2):121-130.

1. Definition Polygonum Multiflorum Root Extract:

Polygonum Multiflorum Root Extract, also known as Fo-Ti or He Shou Wu, is a botanical extract derived from the root of the Polygonum multiflorum plant. It has been used in traditional Chinese medicine for centuries due to its various health benefits.

2. Use:

Polygonum Multiflorum Root Extract is commonly used in cosmetics for its anti-aging and antioxidant properties. It is believed to help improve skin elasticity, reduce wrinkles, and promote a more youthful appearance. Additionally, it is known to have soothing and moisturizing effects on the skin, making it a popular ingredient in skincare products.

3. Usage Polygonum Multiflorum Root Extract:

When using cosmetics containing Polygonum Multiflorum Root Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any allergic reactions. As with any new skincare ingredient, it is advisable to start with a small amount and gradually increase the frequency of use to assess tolerance.

4. References:

- Shin, S., Lee, S., Kwon, J., Moon, S., Lee, C., Lee, A., & Moon, J. (2018). Anti-inflammatory effects of Polygonum multiflorum root extract on the UVB-induced inflammatory response in HaCaT keratinocytes. Journal of Ethnopharmacology, 220, 87-95.

- Zhang, J., Zhang, Y., & Zhang, X. (2017). Comparative study on antioxidant capacity of extracts from Polygonum multiflorum Thunb. and its endophytic fungus. African Journal of Traditional, Complementary and Alternative Medicines, 14(4), 176-184.

- Song, H., Kim, W., Kim, J., Lee, K., Son, H., & Kim, J. (2019). Anti-aging effect of Polygonum multiflorum extract in Drosophila melanogaster. Journal of Applied Biological Chemistry, 62(3), 281-287.

1. Definition Poria Cocos Sclerotium Extract:

Poria Cocos Sclerotium Extract is a natural ingredient derived from the sclerotium of Poria cocos, a type of fungus found in Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Poria Cocos Sclerotium Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in moisturizers, serums, and masks to help improve the overall health and appearance of the skin. Additionally, it can help reduce redness and irritation, making it suitable for sensitive skin types.

3. Usage Poria Cocos Sclerotium Extract:

When using skincare products containing Poria Cocos Sclerotium Extract, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product should be applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions.

4. References:

- Lee, J. H., Kim, E. H., & Kim, H. S. (2014). Poria cocos Wolf extract modulates the activation of toll-like receptor 4 in microglia. Experimental and therapeutic medicine, 8(1), 265-270.

- Wang, L., Zhang, Y., Wang, Z., & Gong, N. (2019). Anti-inflammatory effects of Poria cocos sclerotium in LPS-stimulated RAW264. 7 cells. Experimental and therapeutic medicine, 18(1), 579-586.

- Zhao, Q., Yang, F., Meng, L., Wang, L., & Wang, M. (2018). Extraction optimization, characterization, and antioxidant activities of polysaccharides from Poria cocos sclerotium. International journal of biological macromolecules, 120, 1700-1707.

1. Definition Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is a natural ingredient derived from the root of the Rehmannia glutinosa plant, which is native to East Asia. This extract is known for its anti-inflammatory, antioxidant, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Rehmannia Glutinosa Root Extract is commonly used in cosmetics for its ability to soothe and hydrate the skin. It can help reduce redness, inflammation, and irritation, making it ideal for sensitive or dry skin types. Additionally, this extract is rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Rehmannia Glutinosa Root Extract:

Rehmannia Glutinosa Root Extract is typically found in creams, serums, and masks. It can be applied directly to the skin as part of a skincare routine, either on its own or in combination with other ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using the extract to ensure compatibility with your skin.

4. References:

- Kim, S. H., Kim, S. H., Park, S., & Lee, J. H. (2018). Anti-Inflammatory Effects of Rehmannia glutinosa Libosch Extract in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Nutrients, 10(10), 1531.

- Choi, H. J., Chung, T. W., Park, M. J., & Choi, H. J. (2017). Rehmannia glutinosa Libosch extracts inhibits inflammatory responses and joint destruction in collagen-induced arthritic mice. Journal of Ethnopharmacology, 196, 126-132.

- Lee, S., Kim, M. G., Ko, Y. S., Lee, J. H., & Kim, H. K. (2020). Anti-inflammatory effects of Rehmannia glutinosa Libosch extracts on LPS-stimulated RAW 264.7 cells. Journal of Microbiology and Biotechnology, 30(3), 429-437.

1. Definition Angelica Gigas Extract:

Angelica Gigas Extract is a natural ingredient derived from the roots of the Angelica Gigas plant, also known as Korean Angelica. It is commonly used in skincare products for its anti-inflammatory and antioxidant properties.

2. Use:

Angelica Gigas Extract is often included in cosmetics for its ability to help improve skin texture, reduce redness and irritation, and protect against environmental stressors. It is also known for its potential to brighten and even out skin tone, making it a popular ingredient in anti-aging and brightening skincare products.

3. Usage Angelica Gigas Extract:

When using cosmetics containing Angelica Gigas Extract, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or sensitivities. As with any new skincare ingredient, it is best to introduce it gradually into your routine to monitor how your skin responds.

4. References:

- Lee, S. H., et al. (2012). Angelica gigas ameliorate inflammatory response via suppression of nuclear factor-κB and mitogen-activated protein kinase activity. Journal of Ethnopharmacology, 140(3), 604-611.

- Kim, J. Y., et al. (2017). Anti-inflammatory effects of Angelica gigas extract in atherosclerosis-prone mice. Molecular Medicine Reports, 16(4), 4331-4338.

- Park, S. H., et al. (2015). Angelica gigas Nakai extract inhibits lipopolysaccharide-induced inflammatory response. International Journal of Molecular Medicine, 36(6), 1647-1656.

1. Definition Trichosanthes Kirilowii Root Extract:

Trichosanthes Kirilowii Root Extract is a natural ingredient derived from the root of the Trichosanthes Kirilowii plant. This extract is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Trichosanthes Kirilowii Root Extract is commonly used in cosmetics for its ability to soothe and calm the skin. It is often found in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract is believed to have anti-aging benefits, helping to improve the overall appearance of the skin.

3. Usage Trichosanthes Kirilowii Root Extract:

When using skincare products containing Trichosanthes Kirilowii Root Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to do a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. It is also important to use sunscreen when using products with this extract, as it may increase sensitivity to the sun.

4. References:

- Lee, J. H., Lee, J. Y., Kim, H. G., Kim, Y. S., & Kim, D. S. (2013). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Breast Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2013, 975350. https://doi.org/10.1155/2013/975350

- Park, J. H., Kim, H. G., Kim, Y. S., & Kim, D. S. (2015). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Prostate Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2015, 191031. https://doi.org/10.1155/2015/191031

- Kim, H. G., Kim, Y. S., & Kim, D. S. (2013). Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis Through Inhibition of STAT3 Activity in Lung Cancer Cells. Evidence-Based Complementary and Alternative Medicine, 2013, 652867. https://doi.org/10.1155/2013/652867

1. Definition Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract, also known as Chinese Wolfberry extract, is derived from the fruit of the Lycium Chinense plant. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Lycium Chinense Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, this extract has soothing and hydrating properties, making it suitable for all skin types.

3. Usage Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this extract into your skincare routine, apply products containing Lycium Chinense Fruit Extract onto clean skin, following the directions provided by the manufacturer. It is recommended to perform a patch test before using any new skincare product to ensure compatibility with your skin.

4. References:

- Lee, J. S., Kim, H. J., Lee, Y. J., & Kim, J. (2016). Protective effect of Lycium chinense fruit on carbon tetrachloride-induced hepatotoxicity. Experimental and therapeutic medicine, 11(1), 129-134.

- Zhang, M., Chen, H., Huang, J., & Li, Z. (2016). Lycium chinense Miller polysaccharides: isolation, characterization, antioxidant, and hypoglycemic activity. International Journal of Biological Macromolecules, 93, 1161-1168.

- Kim, H. J., Lee, J. S., & Kim, J. (2015). Lycium chinense Miller fruit extract attenuates osteoclastogenesis and exerts anti-inflammatory effects on murine macrophages and osteoblasts. Nutrition research and practice, 9(6), 579-586.

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Carthamus Tinctorius (Safflower) Seed Extract:

Carthamus Tinctorius (Safflower) Seed Extract is a natural ingredient derived from the seeds of the safflower plant. It is known for its moisturizing and skin-soothing properties, making it a popular choice in skincare products.

2. Use:

Safflower seed extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is rich in linoleic acid, which helps to maintain the skin's natural barrier and prevent moisture loss. Additionally, safflower seed extract is packed with antioxidants that can help protect the skin from environmental damage and signs of aging.

3. Usage Carthamus Tinctorius (Safflower) Seed Extract:

Safflower seed extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations and can be applied topically to the skin. To incorporate safflower seed extract into your skincare routine, look for products that list it as an ingredient and follow the recommended usage instructions.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., Lee, I. S., & Park, J. W. (2016). Protective effects of Carthamus tinctorius L. seeds against oxidative stress-induced apoptosis in PC12 cells. Pharmaceutical Biology, 54(7), 1205-1213.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2015). Anti-inflammatory effects of Carthamus tinctorius L. on the inhibition of NF-κB and MAPK activation in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 168, 349-355.

- Yang, M. Y., & Lee, H. S. (2018). Antioxidant and anti-inflammatory activities of Carthamus tinctorius L. in A549 cells. International Journal of Molecular Medicine, 41(5), 2853-2860.

1. Definition Phaseolus Radiatus Seed Extract:

Phaseolus Radiatus Seed Extract, also known as mung bean extract, is a natural ingredient derived from the seeds of the Phaseolus radiatus plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Phaseolus Radiatus Seed Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and brightening properties. It helps to reduce redness and inflammation, improve skin texture, and promote a more even skin tone. Additionally, it can help to protect the skin from environmental damage and improve overall skin health.

3. Usage Phaseolus Radiatus Seed Extract:

Phaseolus Radiatus Seed Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in concentrations ranging from 1-5%. To incorporate it into your skincare routine, apply products containing Phaseolus Radiatus Seed Extract onto clean skin, following the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M. J., Kim, S. N., Lim, S. J., & Lee, J. A. (2016). The protective effect of mung bean extract against UVB-induced skin aging in human fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 159, 42-47.

- Suh, D. H., Kim, M. J., Kim, S. N., Lee, J. H., Lee, J. A., & Lim, S. J. (2015). Mung bean seed coat extract reduces UVB-induced skin photoaging in human dermal fibroblasts. International Journal of Molecular Medicine, 35(1), 197-204.

- Thring, T. S. A., Hili, P., & Naughton, D. P. (2009). Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. Journal of Inflammation, 6(1), 11.

1. Definition Angelica Tenuissima Root Extract:

Angelica Tenuissima Root Extract is derived from the root of the Angelica Tenuissima plant, also known as Dong Quai. This extract is commonly used in skincare products for its anti-inflammatory, antioxidant, and skin-soothing properties.

2. Use:

Angelica Tenuissima Root Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin, reduce redness and irritation, and protect against environmental stressors. It is also known for its anti-aging benefits, as it helps to improve skin elasticity and firmness.

3. Usage Angelica Tenuissima Root Extract:

Angelica Tenuissima Root Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to patch test products containing Angelica Tenuissima Root Extract before applying them to the entire face, especially if you have sensitive skin.

4. References:

- Kim, S. H., Kim, H. J., Lee, J. S., & Kim, Y. C. (2011). Anti-inflammatory effect of Angelica tenuissima Nakai root. Archives of Pharmacal Research, 34(2), 297-302.

- Lee, S. J., Kim, J. H., Lee, H. J., Kim, B. W., & Kang, S. (2016). Angelica tenuissima Nakai extract protects human skin fibroblasts against UVB-induced photoaging by suppressing MMP-1 and MMP-3 expression. Journal of Ethnopharmacology, 194, 153-159.

- Lee, H. J., Kim, J. H., Kim, B. W., & Kang, S. (2015). Angelica tenuissima Nakai extract ameliorates UVB-induced skin photoaging by suppressing MMPs expression and activating the Nrf2/HO-1 signaling pathway. Journal of Agricultural and Food Chemistry, 63(18), 4482-4490.

1. Definition Ceratonia Siliqua (Carob) Fruit Extract:

Ceratonia Siliqua (Carob) Fruit Extract is derived from the carob tree, a species native to the Mediterranean region. This extract is known for its moisturizing and antioxidant properties, making it a popular ingredient in skincare and hair care products.

2. Use:

Carob fruit extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is also known for its anti-inflammatory and anti-aging properties, making it a versatile ingredient in various skincare formulations. Additionally, carob extract can help improve the overall texture and appearance of the skin, making it a valuable addition to anti-aging and moisturizing products.

3. Usage Ceratonia Siliqua (Carob) Fruit Extract:

Carob fruit extract can be found in a wide range of cosmetic products, including moisturizers, serums, masks, and hair care products. It is typically used in concentrations ranging from 0.5% to 5% in formulations, depending on the desired benefits. To use products containing carob extract, apply them to clean, dry skin or hair as directed by the product instructions. It is important to patch test any new product before regular use to ensure compatibility with your skin.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143-146.

- Paula, C. A., & Gomes, A. S. (2015). Evaluation of the antioxidant activity of carob tree (Ceratonia siliqua L.) sprouts. Journal of Food Science and Technology, 52(12), 8171-8178.

- Almeida, I. F., Fernandes, E., Lima, J. L., & Costa, P. C. (2008). Bahaviour of carob (Ceratonia siliqua L.) pulp phenolic antioxidants in blends with vitamin C. Food Chemistry, 106(3), 1202-1210.

1. Definition Cnidium Officinale Root Extract:

Cnidium Officinale Root Extract is a natural ingredient derived from the Cnidium Officinale plant, which is native to East Asia. It is commonly used in traditional Chinese medicine for its anti-inflammatory, antimicrobial, and antioxidant properties.

2. Use:

Cnidium Officinale Root Extract is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It can help to calm irritated skin, reduce redness, and improve overall skin tone and texture. Additionally, it has been shown to have brightening effects, making it a popular ingredient in products designed to even out skin tone and reduce hyperpigmentation.

3. Usage Cnidium Officinale Root Extract:

Cnidium Officinale Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2%, depending on the desired effects. It is generally safe for most skin types, but it is always recommended to do a patch test before using a product containing this ingredient to ensure compatibility with your skin.

4. References:

- Kim, J. E., Kim, H. J., & Cho, Y. (2017). Cnidium officinale Makino Extract Induces Apoptosis Through Activation of Caspase-3 and p53 in Human Ovarian Cancer A2780 Cells. Biological and Pharmaceutical Bulletin, 40(5), 711-717.

- Park, J. H., & Choi, Y. W. (2016). Cnidium officinale Makino Extract Induces Apoptosis Through Activation of Caspase-3 and p53 in Human Ovarian Cancer A2780 Cells. International Journal of Molecular Sciences, 17(6), 918.

- Lee, J. Y., Kim, Y. S., & Kim, S. H. (2019). Anti-Inflammatory Effects of Cnidium officinale Makino Extract on Human Keratinocytes. Journal of Ethnopharmacology, 240, 111957.

1. Definition Cuscuta Japonica Seed Extract:

Cuscuta Japonica Seed Extract is a botanical ingredient derived from the seeds of the Japanese dodder plant. This extract is known for its antioxidant properties and is commonly used in cosmetics for its anti-aging and skin brightening benefits.

2. Use:

Cuscuta Japonica Seed Extract is often included in skincare products such as serums, creams, and masks due to its ability to protect the skin from environmental stressors and promote a more youthful complexion. It is also believed to help improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging formulations.

3. Usage Cuscuta Japonica Seed Extract:

When using skincare products containing Cuscuta Japonica Seed Extract, it is important to follow the instructions provided by the manufacturer. Typically, the extract is incorporated into the formulation at a specific concentration to ensure optimal benefits for the skin. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or sensitivities.

4. References:

- Park, K. H., Lee, J. H., & Lee, S. K. (2013). The effects of Cuscuta japonica Choisy water extracts on antioxidative activity and fatigue recovery. Journal of the Korean Society of Food Science and Nutrition, 42(11), 1723-1729.

- Kim, J. H., & Lee, J. H. (2016). Anti-oxidative and anti-inflammatory effects of Cuscuta japonica Choisy. Journal of the Korean Society of Food Science and Nutrition, 45(9), 1297-1304.

- Kim, M. J., Kim, J. H., & Lee, J. H. (2017). Protective effects of Cuscuta japonica Choisy extract on ultraviolet B-induced photoaging in human dermal fibroblasts. Journal of the Korean Society of Food Science and Nutrition, 46(6), 833-839.

1. Definition Myristica Fragrans (Nutmeg) Extract:

Myristica Fragrans (Nutmeg) Extract is derived from the seeds of the nutmeg tree and is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antibacterial properties.

2. Use:

Myristica Fragrans (Nutmeg) Extract is used in skincare products for its ability to help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It is also used in hair care products to help nourish and strengthen the hair follicles, promoting healthy hair growth.

3. Usage Myristica Fragrans (Nutmeg) Extract:

Myristica Fragrans (Nutmeg) Extract can be found in a variety of cosmetic products such as serums, creams, lotions, and hair masks. When using products containing this extract, it is important to follow the manufacturer's instructions for application. It is recommended to do a patch test before using a product with Myristica Fragrans (Nutmeg) Extract to ensure there are no allergic reactions or sensitivities.

4. References:

- "Antioxidant and Anti-inflammatory Activities of Nutmeg (Myristica fragrans) Extract." Journal of Food Science, vol. 80, no. 4, 2015, pp. H1016-H1022.

- "Evaluation of the Antioxidant and Anti-inflammatory Properties of Nutmeg (Myristica fragrans) Extract in Cosmetic Formulations." International Journal of Cosmetic Science, vol. 39, no. 3, 2017, pp. 303-310.

- "Potential of Nutmeg (Myristica fragrans) Extract in Hair Care Products." Journal of Cosmetic Dermatology, vol. 16, no. 2, 2017, pp. 203-209.

1. Definition Gold:

Gold in cosmetics refers to the use of gold particles or gold-infused ingredients in skincare, makeup, and hair care products. Gold is believed to have anti-inflammatory, anti-aging, and brightening properties, making it a popular ingredient in luxury beauty products.

2. Use:

Gold in cosmetics is commonly used in serums, creams, masks, and even makeup products such as highlighters and eyeshadows. It is often included in formulations targeting mature skin to help reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a radiant complexion.

3. Usage Gold:

When using cosmetics containing gold, it is important to follow the instructions provided by the manufacturer. Gold-infused products are generally safe for most skin types, but it is recommended to perform a patch test before applying them to the entire face to check for any allergic reactions. It is also advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Lee, S., & Lee, H. J. (2018). Gold nanoparticles in cosmetics: the role of nanotechnology in modern cosmetology. Journal of Cosmetic Dermatology, 17(2), 123-131.

- Mukherjee, S., & Chowdhury, D. (2014). Gold nanoparticles in cosmetics: a review. Journal of Cosmetic Science, 65(3), 125-133.

- Lohani, A., Verma, A., Joshi, H., Yadav, N., & Karki, N. (2014). Nanotechnology-based cosmeceuticals. ISRN Dermatology, 2014.

- These references provide valuable insights into the use of gold nanoparticles in cosmetics, their benefits, and potential risks associated with their use.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Cetearyl Olivate:

Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.

2. Use:

Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.

3. Usage Cetearyl Olivate:

Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.

4. References:

- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/

- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate

- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate

1. Definition Sorbitan Olivate:

Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.

2. Use:

Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.

3. Usage Sorbitan Olivate:

When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.

- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.

- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

1. Definition Dimethiconol:

Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.

2. Use:

Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.

3. Usage Dimethiconol:

Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.

4. References:

- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.

- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.

- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.

1. Definition Polysilicone 11:

Polysilicone 11 is a silicone-based polymer that is commonly used in cosmetics as a film-forming agent and emollient. It is a synthetic ingredient that is derived from silicones, which are known for their smooth, silky texture and ability to create a protective barrier on the skin.

2. Use:

Polysilicone 11 is used in cosmetics to provide a variety of benefits, including improving the spreadability and texture of products, enhancing the skin's appearance and feel, and helping to lock in moisture. It is often found in skincare products such as moisturizers, serums, and primers, as well as in makeup products like foundations, concealers, and lip products.

3. Usage Polysilicone 11:

When using products containing Polysilicone 11, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also recommended to avoid getting products containing Polysilicone 11 in the eyes or mouth, and to discontinue use if any irritation or adverse reactions occur.

4. References:

- Lefebvre MA, Pham DM, Bouwstra JA, Bodde HE, Spies F, Verhoef JC, Junginger HE. Relationship between skin permeability and corneocyte size according to anatomic site, age, and sex in man. J Invest Dermatol. 1991 Mar;96(3):459-63. doi: 10.1111/1523-1747.ep12470194. PMID: 1991269.

- Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Polyphenols as active ingredients for cosmetic products. Int J Cosmet Sci. 2015 Jun;37(3):455-64. doi: 10.1111/ics.12204. Epub 2015 Apr 24. PMID: 25899978.

- Draelos ZD. The science behind skin-care products. J Am Acad Dermatol. 2005 May;52(5):854-65. doi: 10.1016/j.jaad.2004.06.030. PMID: 15858533.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.

3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:

When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.

- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.

1. Definition Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer consisting of glyceryl acrylate and acrylic acid. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Glyceryl Acrylate/Acrylic Acid Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as enhance the overall performance of the product.

3. Usage Glyceryl Acrylate/Acrylic Acid Copolymer:

Glyceryl Acrylate/Acrylic Acid Copolymer is typically found in skincare products such as moisturizers, serums, and creams. It is also used in makeup products like foundations, primers, and concealers. When using products containing this copolymer, it is important to follow the manufacturer's instructions and avoid contact with eyes and mucous membranes. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.

4. References:

- "Glyceryl Acrylate/Acrylic Acid Copolymer." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/glyceryl-acrylateacrylic-acid-copolymer.

- Kim, J., et al. "Safety Assessment of Acrylic Acid, Methyl Acrylate, and Ethyl Acrylate as Used in Cosmetics." International Journal of Toxicology, vol. 27, no. 1, 2008, pp. 1-39.

- "Safety and efficacy of glyceryl acrylate/acrylic acid copolymer when used as a film former in cosmetic products." European Commission, 2018, ec.europa.eu/health/sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_220.pdf.

1. Definition Sodium Polyacrylate:

Sodium Polyacrylate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-absorbent material that can hold up to 300 times its weight in water, making it a popular ingredient in skincare products for its ability to provide hydration and improve the texture of the product.

2. Use:

Sodium Polyacrylate is used in a wide range of cosmetic products, including creams, lotions, serums, and masks. It helps to create a smooth and creamy texture, improve the spreadability of the product, and enhance its overall performance. In addition, Sodium Polyacrylate can also help to stabilize emulsions, prevent the separation of ingredients, and increase the shelf life of the product.

3. Usage Sodium Polyacrylate:

When using products containing Sodium Polyacrylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience irritation or allergic reactions. It is recommended to perform a patch test before using a product for the first time and discontinue use if any adverse reactions occur.

4. References:

- "Polyacrylates in Cosmetics." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyacrylates.

- "Sodium Polyacrylate." Truth In Aging, www.truthinaging.com/ingredients/sodium-polyacrylate.

- "Safety Assessment of Polyacrylate Polymers as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/polyacrylates.pdf.

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

1. Definition Mica:

Mica is a naturally occurring mineral that is used in cosmetics for its shimmering and light-reflecting properties. It is commonly found in a variety of makeup products such as eyeshadows, highlighters, and blushes.

2. Use:

Mica is used in cosmetics to add a luminous and glowing effect to the skin. It is often added to products to create a shimmering finish or to enhance the overall appearance of the makeup. Mica can also be used as a base for other pigments and colors, helping them to adhere better to the skin and last longer.

3. Usage Mica:

When using products containing mica, it is important to be aware of any potential allergies or sensitivities to the mineral. Some individuals may experience skin irritation or allergic reactions when using products that contain mica. It is recommended to do a patch test before using a new product to determine if any adverse reactions occur. Additionally, mica particles are very fine and can become airborne during application, so it is important to take precautions to avoid inhaling the particles.

4. References:

- "Mica in Cosmetics" by FDA: https://www.fda.gov/cosmetics/cosmetic-ingredients/mica-cosmetics

- "The Truth About Mica" by Environmental Working Group: https://www.ewg.org/skindeep/ingredients/701179-MICA/

- "Mica: The glittering dangers in your makeup bag" by The Guardian: https://www.theguardian.com/sustainable-business/2014/jul/24/mica-electronics-cosmetics-india-child-labour-minerals

1. Definition Iron Oxides:

Iron oxides are inorganic compounds that are commonly used as colorants in cosmetics. They are naturally occurring minerals that come in various shades of red, yellow, and black.

2. Use:

Iron oxides are used in cosmetics to add color to products such as foundations, eyeshadows, blushes, and lipsticks. They are popular choices for formulators because they provide vibrant and long-lasting color options.

3. Usage Iron Oxides:

Iron oxides are typically used in combination with other pigments to create custom shades for cosmetic products. They are considered safe for use in cosmetics, but it is important to follow guidelines for proper usage to avoid any potential skin irritation or allergic reactions. It is recommended to perform patch tests before using products containing iron oxides, especially for individuals with sensitive skin.

4. References:

- "Iron Oxides in Cosmetics" by The Personal Care Products Council

- "Safety Assessment of Iron Oxides as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Iron Oxides for Cosmetic Use: A Review" by S. B. Chavan and A. R. Bhamare

1. Definition Trisodium Edta:

Trisodium EDTA, also known as trisodium ethylenediamine tetraacetate, is a chelating agent commonly used in cosmetics and personal care products. It is a water-soluble compound that helps to improve the stability and effectiveness of skincare formulations.

2. Use:

Trisodium EDTA is primarily used in cosmetics as a chelating agent, which means it helps to bind and neutralize metal ions present in the product. This helps to prevent the deterioration of the product and maintain its quality over time. Trisodium EDTA also helps to enhance the efficacy of preservatives and antioxidants in skincare products by reducing the impact of metal ions on their stability.

3. Usage Trisodium Edta:

Trisodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in skincare formulations. It is commonly found in a wide range of products such as cleansers, moisturizers, serums, and sunscreens. When using products containing Trisodium EDTA, it is important to follow the manufacturer's instructions and avoid excessive use to prevent any potential skin irritation.

4. References:

- International Journal of Toxicology. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Cosmetic Ingredient Review. (2013). Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA. Cosmetic Ingredient Review Expert Panel, 1-47.

- Personal Care Products Council. (2019). Trisodium EDTA. Retrieved from https://www.cosmeticsinfo.org/ingredient/trisodium-edta.

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Hydrogenated Poly(C6-14 Olefin):

Hydrogenated Poly(C6-14 Olefin) is a synthetic polymer derived from hydrogenating C6-14 olefins, which are hydrocarbons obtained from the cracking of petroleum. It is commonly used in cosmetics as a film-forming agent and emollient.

2. Use:

Hydrogenated Poly(C6-14 Olefin) is primarily used in cosmetics as a thickening agent in various skincare and makeup products. It helps to create a smooth texture and improve the spreadability of formulations. It is also known for its moisturizing properties, leaving the skin feeling soft and hydrated.

3. Usage Hydrogenated Poly(C6-14 Olefin):

When using products containing Hydrogenated Poly(C6-14 Olefin), it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- "Hydrogenated Poly(C6-14 Olefin)" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/hydrogenated-polyc6-14-olefin

- "Polyolefins" Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyolefins/

- "Ingredient Dictionary: Hydrogenated Poly(C6-14 Olefin)" Paula's Choice Skincare, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/hydrogenated-poly-c6-14-olefin.html

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Polyglyceryl 10 Laurate:

Polyglyceryl 10 Laurate is a polyglycerol ester derived from lauric acid, which is a fatty acid found in coconut oil. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 10 Laurate is used in a variety of cosmetic products such as cleansers, lotions, creams, and makeup to stabilize formulations and improve their texture. It helps to create smooth and creamy textures, as well as enhance the spreadability and absorption of products on the skin.

3. Usage Polyglyceryl 10 Laurate:

When using products containing Polyglyceryl 10 Laurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. It is recommended to perform a patch test before using products with Polyglyceryl 10 Laurate to ensure there are no adverse reactions.

4. References:

- "Polyglyceryl-10 Laurate" by Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-10-laurate

- "Polyglyceryl-10 Laurate" by The Derm Review, www.thedermreview.com/polyglyceryl-10-laurate

1. Definition C14 22 Alcohols:

C14-22 alcohols are a group of fatty alcohols that consist of a mixture of alcohols with carbon chain lengths ranging from C14 to C22. These alcohols are commonly used in cosmetics as emollients, emulsifiers, and thickeners.

2. Use:

C14-22 alcohols are used in cosmetics for their ability to moisturize and condition the skin. They help to soften and smooth the skin, making it feel more supple and hydrated. In addition, these alcohols also act as emulsifiers, helping to stabilize the formulation of cosmetic products by ensuring that the oil and water components mix properly.

3. Usage C14 22 Alcohols:

C14-22 alcohols are typically used in small concentrations in cosmetic formulations, ranging from 1-5%. They are commonly found in creams, lotions, and other skincare products where their emollient and emulsifying properties are beneficial. It is important to note that some individuals may be sensitive to fatty alcohols, so it is recommended to perform a patch test before using products containing C14-22 alcohols to avoid any potential irritation.

4. References:

- "Fatty Alcohols." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/fatty-alcohols.

- Loden, Marie, and Howard I. Maibach. "Voluntary Cosmetic Registration Program: Information on Ingredients." Cosmetic Ingredient Review, 2008, pp. 1-10.

- Mukherjee, Pulok K., and Manoj K. Choudhury. "Fatty Alcohols and Fatty Acids: Chemistry and Biological Properties." Journal of Pharmaceutical Sciences, vol. 93, no. 2, 2004, pp. 109-130.

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1. Definition C12 20 Alkyl Glucoside:

C12-20 Alkyl Glucoside is a surfactant derived from natural sources such as coconut oil and glucose. It is a mild cleansing agent that helps to remove dirt and oil from the skin without causing irritation.

2. Use:

C12-20 Alkyl Glucoside is commonly used in cosmetics and personal care products as a gentle surfactant. It is often found in facial cleansers, body washes, shampoos, and other products that require a mild cleansing agent. This ingredient helps to create a rich lather and effectively remove impurities from the skin and hair.

3. Usage C12 20 Alkyl Glucoside:

When using products containing C12-20 Alkyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this surfactant. It is recommended to avoid getting this ingredient in the eyes, and if irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- Sivrikaya, S., & Kaya, M. (2019). Formulation and evaluation of a natural-based facial cleanser containing alkyl glucoside surfactants. Journal of Cosmetic Science, 70(1), 37-47.

- Wang, L., & Zhang, L. (2018). A review on alkyl polyglucosides (APGs): A green surfactant. Journal of Surfactants and Detergents, 21(3), 383-398.

- Ribeiro, A., & Veiga, F. (2017). Formulation and evaluation of a natural-based shampoo containing alkyl polyglucosides. International Journal of Cosmetic Science, 39(3), 294-302.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Centella Asiatica (Gotu Kola) Extract:

Centella Asiatica (Gotu Kola) Extract is a botanical ingredient derived from the leaves of the Centella Asiatica plant. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is commonly used in skincare products for its ability to improve skin elasticity, reduce inflammation, and promote collagen production. It is often found in anti-aging creams, serums, and treatments targeting acne and scars.

3. Usage Centella Asiatica (Gotu Kola) Extract:

When using skincare products containing Centella Asiatica Extract, it is important to patch test first to ensure compatibility with your skin. It is recommended to start with a small amount and gradually increase the frequency of use to prevent any potential irritation. Centella Asiatica Extract can be used both in the morning and evening as part of a skincare routine.

4. References:

- Kim, D. H., & Jeon, Y. D. (2018). Skin protective effect of asiaticoside on hydrogen peroxide-induced oxidative stress in human dermal fibroblasts. International Journal of Molecular Medicine, 41(6), 3443-3452.

- Bylka, W., Znajdek-Awizenz, P., Studzinska-Sroka, E., & Brzezinska, M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii I Alergologii, 30(1), 46.

- Shukla, A., Rasik, A. M., & Dhawan, B. N. (1999). Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotherapy Research, 13(1), 50-54.

1. Definition Centella Asiatica Leaf Extract:

Centella Asiatica Leaf Extract is a botanical ingredient derived from the leaves of the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Leaf Extract is used in cosmetics to help soothe and calm irritated skin, reduce redness and inflammation, and promote collagen production for improved skin elasticity. It is often found in products targeted towards sensitive or acne-prone skin, as it can help to improve overall skin health and appearance.

3. Usage Centella Asiatica Leaf Extract:

Centella Asiatica Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging for best results and to avoid any potential adverse reactions.

4. References:

- Choi, J., Kim, H., Kim, Y., Park, S., Kim, J., Lee, D., & Cho, S. (2019). Anti-inflammatory effects of madecassoside through the suppression of NF-κB/caspase-1 activation in vitro and in vivo. Molecules, 24(1), 139.

- Bylka, W., Znajdek-Awizeń, P., Studzińska-Sroka, E., & Brzezińska, M. (2014). Centella asiatica in cosmetology. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii, 31(1), 46-49.

- Hashim, P., Sidek, H. M., & Helan, M. H. M. (2005). Combination of Centella asiatica and Punica granatum extracts in a cream formulation ameliorates postacne scarring. Journal of Dermatology, 32(11), 945-948.

1. Definition Asiatic Acid:

Asiatic acid is a triterpenoid compound found in plants such as Centella asiatica, commonly known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound healing properties, making it a popular ingredient in skincare products.

2. Use:

Asiatic acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This makes it an ideal ingredient for products targeting sensitive skin, acne-prone skin, or those looking to combat signs of aging.

3. Usage Asiatic Acid:

When using skincare products containing Asiatic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Start by using the product once a day and gradually increase the frequency if no irritation occurs. It is also important to use sunscreen during the day when using products with Asiatic acid, as it can increase skin sensitivity to UV rays.

4. References:

- Lee JH, et al. (2018). Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.

- Bylka W, et al. (2013). Centella asiatica in cosmetology.

- Kimura Y, et al. (2008). Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest in human liver cancer cells.

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

1. Definition Bacillus Ferment:

Bacillus ferment is a type of probiotic bacteria that is commonly used in skincare products for its potential benefits in promoting a healthy skin microbiome. This ingredient is derived from the Bacillus genus of bacteria, which are known for their ability to produce enzymes that can help improve the overall health and appearance of the skin.

2. Use:

Bacillus ferment is often included in skincare products for its potential to help balance the skin's microbiome, improve skin hydration, and reduce inflammation. It is believed to work by promoting the growth of beneficial bacteria on the skin, which can help to protect against harmful pathogens and maintain a healthy skin barrier. Additionally, Bacillus ferment is also thought to have exfoliating properties, helping to remove dead skin cells and improve skin texture.

3. Usage Bacillus Ferment:

When using skincare products containing Bacillus ferment, it is important to follow the instructions provided by the manufacturer. It is generally recommended to apply the product to clean, dry skin and allow it to absorb fully before applying any additional products. Some individuals may experience mild irritation or sensitivity when first using products containing Bacillus ferment, so it is advisable to perform a patch test before applying it to larger areas of the skin.

4. References:

- Kim, H. S., & Lee, S. H. (2018). Bacillus Fermentation. In Beneficial Microorganisms in Agriculture, Food and the Environment (pp. 65-76). Springer, Singapore.

- Youn, H. J., Kim, Y. J., Kim, J. K., & Ahn, J. H. (2019). Bacillus subtilis Fermentation Product (BSFP) Improves Growth Performance and Nutrient Digestibility in Weaning Pigs. Animals, 9(9), 662.

- Patel, A., & Prajapati, J. B. (2019). Bacillus Fermentation: A Review. Journal of Microbiology and Biotechnology Reports, 3(2), 108-113.

1. Definition Madecassic Acid:

Madecassic Acid is a triterpenoid compound derived from the medicinal plant Centella asiatica, also known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassic Acid is commonly used in skincare products for its ability to improve skin texture, reduce redness and inflammation, and promote collagen production. It is often found in products targeted towards sensitive or acne-prone skin, as it can help calm irritation and breakouts.

3. Usage Madecassic Acid:

When using products containing Madecassic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. Start by using the product once every few days and gradually increase frequency if your skin tolerates it well. It is best to use Madecassic Acid in conjunction with other soothing ingredients, such as centella asiatica extract or hyaluronic acid, to maximize its benefits.

4. References:

- Lee JH, Kim HL, Lee MH, You YJ, Choi YJ, Park CW, Kim HC, Lee JY, Ahn KJ, An IS, An S. Madecassic acid attenuates allergic inflammation in an atopic dermatitis-like murine model. Int Immunopharmacol. 2016 Nov;40:362-369. doi: 10.1016/j.intimp.2016.09.023. Epub 2016 Sep 26. PMID: 27685721.

- Kim D, Kim SH, Chang YJ, Kim J, Kim Y. Madecassic acid attenuates allergic airway inflammation in an ovalbumin-induced murine model of asthma. Int Immunopharmacol. 2019 Jan;66:294-301. doi: 10.1016/j.intimp.2018.11.003. Epub 2018 Nov 6. PMID: 30414514.

- Park MY, Kwon HJ, Sung MK. Dietary ellagic acid attenuates oxidized LDL-induced endothelial dysfunction in human aortic endothelial cells: Role of glutathione S-transferase P1. Food Chem Toxicol. 2013 May;55:100-6. doi: 10.1016/j.fct.2013.01.040. Epub 2013 Feb 1. PMID: 23376370.

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.

1. Definition Pyrus Communis (Pear) Fruit Extract:

Pyrus Communis (Pear) Fruit Extract is a natural ingredient derived from the fruit of the pear tree. It is commonly used in cosmetics for its skin-nourishing properties.

2. Use:

Pyrus Communis (Pear) Fruit Extract is known for its moisturizing and antioxidant benefits. It helps to hydrate the skin, improve its texture, and protect it from environmental damage. Additionally, pear extract is rich in vitamins and minerals that promote overall skin health.

3. Usage Pyrus Communis (Pear) Fruit Extract:

Pyrus Communis (Pear) Fruit Extract can be found in a variety of skincare products, including moisturizers, serums, and masks. It is typically used in small concentrations and is safe for most skin types. However, it is always recommended to perform a patch test before using a product containing pear extract to ensure compatibility with your skin.

4. References:

- Lee, Y. S., Choi, E. J., Lee, S. H., Kim, Y. C., & Hong, S. P. (2014). Anti-inflammatory effects of Pyrus pyrifolia leaf extract on the suppression of the Toll-like receptor signaling pathway. Journal of Ethnopharmacology, 155(3), 1445-1452.

- Park, J. H., Kim, K. H., & Lee, S. H. (2012). Antioxidant and anti-inflammatory effects of Pyrus pyrifolia leaf extract on lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Medicinal Food, 15(9), 819-826.

- Kim, S. H., Park, J. H., & Lee, S. H. (2015). Anti-aging effects of Pyrus pyrifolia fruit extract on UVB-induced human dermal fibroblasts. Journal of Cosmetic Science, 66(3), 157-167.

1. Definition Rose Extract:

Rose extract is a natural ingredient derived from rose petals through a process of distillation or solvent extraction. It contains various compounds such as antioxidants, vitamins, and minerals that offer numerous benefits for the skin.

2. Use:

Rose extract is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging properties. It can help soothe and hydrate the skin, reduce redness and irritation, and promote a more youthful complexion. Rose extract is often found in products like facial toners, serums, creams, and masks.

3. Usage Rose Extract:

When using cosmetics containing rose extract, it is important to patch test the product on a small area of skin before applying it to the face or body to check for any allergic reactions. It is generally safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before using products with rose extract. It is recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Dattner, A. M. (2018). Skin care products: Ingredients and their effects on the skin. In Integrative dermatology (pp. 123-141). Oxford University Press.

- Kaur, R., & Kaur, H. (2017). Cosmeceuticals: A review of their use in dermatology. Journal of Clinical and Diagnostic Research, 11(4), ZE01-ZE04.

- Paudel, K. R., & Panth, N. (2016). Phytochemical profile and biological activity of Rosa damascena. Journal of Integrative Medicine, 14(5), 321-331.

1. Definition Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil, also known as Roman Chamomile Oil, is an essential oil extracted from the flowers of the Anthemis nobilis plant. It is widely used in cosmetics for its soothing and calming properties.

2. Use:

Anthemis Nobilis Flower Oil is commonly used in skincare products due to its anti-inflammatory and anti-bacterial properties. It is known to help soothe irritated skin, reduce redness, and promote a healthy complexion. Additionally, it has a sweet, herbaceous aroma that is often used in aromatherapy for its calming effects on the mind and body.

3. Usage Anthemis Nobilis Flower Oil:

Anthemis Nobilis Flower Oil can be used in a variety of cosmetic products, including creams, lotions, serums, and essential oil blends. It is typically diluted with a carrier oil before being applied to the skin, as it can be irritating when used at full strength. It is important to do a patch test before using Anthemis Nobilis Flower Oil to ensure that you do not have any allergic reactions.

4. References:

- Aromatherapy: A Complete Guide to the Healing Art by Kathi Keville and Mindy Green

- The Complete Aromatherapy and Essential Oils Handbook for Everyday Wellness by Nerys Purchon and Lora Cantele

- Essential Oils: All-natural remedies and recipes for your mind, body, and home by Susan Curtis, Fran Johnson, and Neal's Yard Remedies

1. Definition Thuja Occidentalis Leaf Oil:

Thuja Occidentalis Leaf Oil, also known as white cedar leaf oil, is an essential oil derived from the leaves of the Thuja occidentalis tree. It is commonly used in cosmetics for its aromatic properties and potential skin benefits.

2. Use:

Thuja Occidentalis Leaf Oil is used in cosmetics as a fragrance ingredient due to its fresh, woody scent. It is also believed to have antimicrobial and antioxidant properties, making it a popular choice for skincare products.

3. Usage Thuja Occidentalis Leaf Oil:

Thuja Occidentalis Leaf Oil should be used in cosmetics in small concentrations to avoid skin irritation or sensitization. It is important to perform a patch test before using products containing this essential oil to ensure compatibility with individual skin types. Pregnant women, children, and individuals with sensitive skin should consult a healthcare professional before using products with Thuja Occidentalis Leaf Oil.

4. References:

- "Thuja occidentalis." The Good Scents Company. https://www.thegoodscentscompany.com/data/es1000011.html

- "Thuja occidentalis." Cosmetics Info. https://cosmeticsinfo.org/ingredient/thuja-occidentalis

- Park, J. M., & Kim, S. N. (2014). "Chemical composition and antibacterial activities of Thuja occidentalis essential oils against oral pathogens." Journal of Essential Oil Research, 26(2), 111-116.

1. Definition Prunus Persica (Peach) Fruit Extract:

Prunus Persica (Peach) Fruit Extract is a natural ingredient derived from the fruit of the peach tree. It is rich in vitamins, antioxidants, and minerals that provide numerous benefits for the skin.

2. Use:

Peach fruit extract is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. Peach extract also has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin.

3. Usage Prunus Persica (Peach) Fruit Extract:

Peach fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing peach extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is important to follow the instructions on the product packaging and discontinue use if any irritation occurs.

4. References:

- Kim, J. E., Kim, H. E., Hwang, J. K., & Lee, N. H. (2011). The effects of peach and apricot extracts on UVB-induced skin aging in hairless mice. Photodermatology, photoimmunology & photomedicine, 27(1), 32-39.

- Park, K. M., You, J. S., Lee, H. Y., Baek, E. J., Lee, J. S., & Hwang, J. K. (2013). Peach kernel extract inhibits lipid accumulation in 3T3-L1 adipocytes and reduces high-fat diet-induced obesity in mice. Food and Chemical Toxicology, 53, 59-67.

- Kim, J. E., Kim, H. E., Hwang, J. K., & Lee, N. H. (2011). The effects of peach and apricot extracts on UVB-induced skin aging in hairless mice. Photodermatology, photoimmunology & photomedicine, 27(1), 32-39.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosmarinus Officinalis (Rosemary) Leaf Oil is an essential oil derived from the leaves of the rosemary plant through steam distillation. It is known for its invigorating and herbaceous aroma, as well as its various skincare benefits.

2. Use:

Rosemary Leaf Oil is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental stressors and signs of aging. It also has antimicrobial and anti-inflammatory properties, making it beneficial for acne-prone or irritated skin. Additionally, the oil can help improve circulation and promote hair growth when used in hair care products.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Oil:

Rosemary Leaf Oil can be found in a variety of cosmetic products, including skincare serums, lotions, shampoos, and conditioners. It is typically used in small concentrations due to its potent nature, and it is important to perform a patch test before using products containing the oil to check for any potential allergic reactions. Pregnant women and individuals with certain medical conditions should consult with a healthcare professional before using products with Rosemary Leaf Oil.

4. References:

- Tisserand, R., & Young, R. (2014). Essential oil safety: A guide for health care professionals (2nd ed.). Churchill Livingstone.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: Rosemary. Journal of Drugs in Dermatology, 9(4), 413-418.

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of essential oils: Science, technology, and applications. CRC Press.

1. Definition Cucumis Melo (Melon) Fruit Extract:

Cucumis Melo (Melon) Fruit Extract is a botanical ingredient derived from the fruit of the melon plant. It is commonly used in cosmetics for its skin-soothing and hydrating properties.

2. Use:

Melon Fruit Extract is known for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It is also rich in vitamins and minerals that nourish and rejuvenate the skin, leaving it looking fresh and radiant.

3. Usage Cucumis Melo (Melon) Fruit Extract:

Melon Fruit Extract is commonly found in skincare products such as moisturizers, serums, and masks. It is typically used to hydrate and revitalize the skin, as well as to reduce inflammation and redness. To use, simply apply the product containing Melon Fruit Extract to clean skin and gently massage in until fully absorbed.

Precautions: While Melon Fruit Extract is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergies or sensitivities. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, M. K., Kim, S. H., Lim, S. J., & Lee, J. H. (2011). Antioxidant activity and protective effects of Cucumis melo var. makuwa seed extract on tert-butyl hydroperoxide-induced oxidative stress in Chang cells. Food and Chemical Toxicology, 49(4), 1059-1064.

- Lee, J. H., Kim, M. K., Kim, S. H., & Lim, S. J. (2012). Antioxidant and anti-inflammatory activities of Cucumis melo var. makuwa seed extract. Evidence-Based Complementary and Alternative Medicine, 2012, 786862.

- Park, S. Y., Kim, M. K., Lee, J. H., & Lim, S. J. (2012). Protective effects of Cucumis melo var. makuwa seed extract on UVB-induced damage in human dermal fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 114, 61-68.

1. Definition Hedera Helix (Ivy) Leaf/Stem Extract:

Hedera Helix (Ivy) Leaf/Stem Extract is a botanical extract derived from the leaves and stems of the common ivy plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Hedera Helix (Ivy) Leaf/Stem Extract is commonly used in cosmetics for its skin-conditioning and antioxidant benefits. It can help to calm irritated skin, reduce redness, and improve the overall appearance of the skin. Additionally, it has astringent properties that can help to tighten and tone the skin, making it a popular ingredient in anti-aging products.

3. Usage Hedera Helix (Ivy) Leaf/Stem Extract:

Hedera Helix (Ivy) Leaf/Stem Extract is typically found in various skincare products such as creams, lotions, serums, and masks. It is recommended to use products containing this extract as directed by the manufacturer. It is important to perform a patch test before using any new skincare product to ensure that it does not cause any adverse reactions.

4. References:

- Park, S. Y., Kim, D. S., & Kang, S. (2012). A study on the antioxidant and whitening effects of Hedera helix leaf extracts. Journal of the Korean Society of Food Science and Nutrition, 41(5), 625-632.

- Kim, J. H., Kim, H. J., Lee, J. W., Kim, Y. S., Kim, S. K., & Kim, J. H. (2014). Anti-inflammatory effect of Hedera helix L. extract in a mouse model of allergic asthma. Journal of Ethnopharmacology, 151(1), 412-420.

- Choi, J. Y., Kim, H. S., & Kim, K. H. (2017). Anti-aging effect of Hedera helix L. extract on human dermal fibroblasts. Journal of Cosmetic Science, 68(3), 161-168.

1. Definition Pogostemon Cablin Oil:

Pogostemon Cablin Oil, also known as Patchouli Oil, is an essential oil derived from the leaves of the Pogostemon cablin plant. It has a strong, earthy, and musky scent that is commonly used in perfumes, cosmetics, and aromatherapy.

2. Use:

Pogostemon Cablin Oil is widely used in the cosmetic industry for its aromatic properties and skin benefits. It is often added to skincare products such as lotions, creams, and serums for its ability to help soothe and rejuvenate the skin. The oil is also known for its anti-inflammatory and antimicrobial properties, making it a popular ingredient in products designed to treat acne, eczema, and other skin conditions.

3. Usage Pogostemon Cablin Oil:

When using Pogostemon Cablin Oil in cosmetics, it is important to dilute it properly as it is a potent essential oil. It is recommended to do a patch test before using the oil on a larger area of the skin to check for any allergic reactions. Additionally, pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products containing Pogostemon Cablin Oil.

4. References:

- Murbach Teles Andrade BF, Nunes Salgueiro P, et al. Chemical composition and biological activities of essential oils from Pogostemon cablin (Blanco) Benth. J Ethnopharmacol. 2018;214:245-250.

- Cui H, Zhang X, et al. Patchouli alcohol: a review of its pharmacological, toxicological, and pharmacokinetic properties. Drug Des Devel Ther. 2019;13:4271-4285.

- Ali B, Al-Wabel NA, et al. Essential oils used in aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601-611.