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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) |  Good for dry skin Moisturizing |
| 2 4 | A | (Fragrance, Preservative) | |
| 1 | - | Good for dry skin Anti Aging | |
| 2 | A | (Deodorant, Skin Conditioning) | |
| 1 | A |  Bad for oily skin  Fungal Acne Trigger | |
| 1 | A | (Solvent, Masking, Perfuming, Skin Conditioning, Emollient) | |
| 1 | A | (Solvent, Skin Conditioning, Masking, Emollient, Fragrance, Hair Conditioning) | Bad for oily skin Fungal Acne Trigger |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming) | |
| 1 3 | - | | |
| 1 | - | (Skin Conditioning, Emollient) | |
| 1 | A | (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous) | Cleansing |
| 1 | - | (Skin Conditioning, Emollient, Hair Conditioning, Abrasive) | |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 1 | A | Bad for oily skin | |
| 1 | A | (Skin Conditioning) | Good for dry skin Bad for oily skin |
| 1 | A | (Skin Conditioning, Emollient, Emulsifying, Surfactant) | Cleansing |
| 1 | A | (Skin Conditioning, Masking, Perfuming) | |
| 1 | A | (Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding) | |
| 1 | A | (Solvent, Masking, Fragrance, Antioxidant, Plasticizer, Deodorant) | |
| 2 | B | (Emulsifying, Surfactant) | Cleansing |
| 1 | - | (Masking, Fragrance, Flavoring Agent) |  Fragrance-free |
| 1 | B | (Skin Conditioning, Emollient, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 | A | (Skin Conditioning, Fragrance, Skin-Conditioning Agent -Occlusive) | Bad for oily skin Fungal Acne Trigger |
| 1 | - | (Humectant) | |
| 1 | - | (Solvent, Perfuming, Fragrance) | |
| 1 | - | (Solvent, Perfuming, Fragrance) | |
| 2 | - | (Masking, Perfuming) | |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 | B | (Solvent, Perfuming, Fragrance, Emollient) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 2 | - | (Solvent, Viscosity Decreasing Agent, Viscosity Controlling) | |
| 1 | A | (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents) | Good for dry skin |
| 1 | A | (Solvent) | |
| 1 3 | A | (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent) |  Silicone Moisturizing |
| 2 | B | (Opacifying, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding, Film Forming) | |
| 1 | - | (Viscosity Controlling, Emulsion Stabilising, Film Forming) | |
| 1 | B | (Humectant, Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin |
| 1 | - | (Antioxidant) | |
| 1 | A | (Solvent, Skin Conditioning) | |
| 1 2 | - | (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant) | Cleansing |
| 1 4 | B | (Denaturant , pH adjusting agent, pH adjusting agent) | |
| 2 3 | A | (Skin Conditioning, Antioxidant) | Anti Aging |
| 1 | A | (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising) | Promotes Wound Healing Moisturizing |
| 1 | - | (Solvent, Masking, Perfuming) | |
| 1 | - | (Skin Conditioning, Humectant, Hair Conditioning) | |
| 1 | A | (Humectant, Skin Conditioning) | Good for dry skin Promotes Wound Healing |
| 1 | - | (Humectant, Hair Conditioning, Skin Conditioning) | Promotes Wound Healing |
| 1 | - | (Skin Conditioning, Humectant) | |
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Ethylhexylglycerin
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Butyrospermum Parkii (Shea) Butter
1. Definition Butyrospermum Parkii (Shea) Butter:
Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.2. Use:
Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.3. Usage Butyrospermum Parkii (Shea) Butter:
When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.4. References:
- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.
- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.
- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.
Caprylic/ Capric Triglyceride
1. Definition Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.2. Use:
Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.3. Usage Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.4. References:
- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.
- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.
- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.
Cocos Nucifera (Coconut) Oil
1. Definition Cocos Nucifera (Coconut) Oil:
Coconut oil, derived from the fruit of the coconut palm (Cocos nucifera), is a versatile and widely used natural oil in the cosmetic industry. It is rich in fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.2. Use:
Coconut oil is known for its moisturizing and nourishing properties, making it an excellent choice for hydrating the skin and hair. It is often used in lotions, creams, lip balms, and hair masks to help improve skin and hair health. Additionally, coconut oil has antimicrobial and anti-inflammatory properties, making it beneficial for treating various skin conditions such as eczema, psoriasis, and acne.3. Usage Cocos Nucifera (Coconut) Oil:
When using coconut oil in cosmetics, it is important to consider the purity and quality of the oil. Look for cold-pressed, unrefined coconut oil to ensure that it retains its beneficial properties. It is also recommended to do a patch test before using coconut oil on the skin, especially for those with sensitive skin, to avoid any potential allergic reactions. Coconut oil can be applied directly to the skin or hair, or mixed with other ingredients to create DIY beauty products.4. References:
- Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of cosmetic science, 54(2), 175-192.
- Evangelista, M. T., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014). The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. International Journal of Dermatology, 53(1), 100-108.
- Nevin, K. G., & Rajamohan, T. (2010). Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clinical biochemistry, 43(4-5), 349-357.
Xanthan Gum
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Aloe Barbadensis (Aloe Vera) Leaf Juice
1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.2. Use:
Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.4. References:
- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.
- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.
- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.
Helianthus Annuus (Sunflower) Oil
1. Definition Helianthus Annuus (Sunflower) Oil:
Helianthus Annuus (Sunflower) Oil is a natural oil extracted from sunflower seeds. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Sunflower oil is commonly used in cosmetics for its moisturizing properties. It helps to hydrate and nourish the skin, leaving it soft and smooth. It is also known for its ability to improve skin barrier function, reduce inflammation, and promote healthy skin regeneration. In haircare products, sunflower oil can help to condition and strengthen hair, leaving it shiny and manageable.3. Usage Helianthus Annuus (Sunflower) Oil:
Sunflower oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to creams, lotions, and serums to enhance their hydrating properties. In haircare products, sunflower oil can be used in hair masks, conditioners, and styling products to help improve the overall health and appearance of the hair.Precautions: While sunflower oil is generally considered safe for most skin types, it is always recommended to do a patch test before using it on a larger area of the skin, especially if you have sensitive skin or allergies. If any irritation occurs, discontinue use immediately. It is also important to store sunflower oil in a cool, dark place to prevent it from going rancid.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Meier, L., & Stange, R. (2019). Sunflower oil in skincare: a comprehensive review of its benefits. Cosmetics, 6(1), 16.
- Suleman, T., & Van Vuuren, S. (2015). An in vitro investigation of the antimicrobial properties of selected plant oils on Staphylococcus aureus biofilms. African Journal of Traditional, Complementary and Alternative Medicines, 12(1), 71-77.
Cetearyl Alcohol
1. Definition Cetearyl Alcohol:
Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.2. Use:
Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.3. Usage Cetearyl Alcohol:
When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.4. References:
- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html
- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/
- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf
Simmondsia Chinensis (Jojoba) Seed Oil Extract
1. Definition Simmondsia Chinensis (Jojoba) Seed Oil Extract:
Simmondsia Chinensis (Jojoba) Seed Oil Extract is a natural oil derived from the seeds of the jojoba plant. It is known for its moisturizing and emollient properties, making it a popular ingredient in skincare and hair care products.2. Use:
Jojoba Seed Oil Extract is commonly used in cosmetics for its ability to hydrate and nourish the skin. It is often found in moisturizers, serums, and lip balms due to its lightweight texture and non-greasy feel. Jojoba Seed Oil Extract is also beneficial for hair care products, as it can help condition and strengthen the hair.3. Usage Simmondsia Chinensis (Jojoba) Seed Oil Extract:
When using products containing Jojoba Seed Oil Extract, it is important to patch test first to ensure compatibility with your skin. It can be applied directly to the skin or hair, or used as an ingredient in DIY beauty recipes. Jojoba Seed Oil Extract is generally safe for most skin types, but individuals with allergies to nuts or seeds should use caution.4. References:
- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." 7th Edition.
- Dweck, A. C. (2003). "The Jojoba Story." Personal Care Magazine, 4(1), 1-4.
- Meier, L., & Sticher, O. (2004). "Jojoba oil—a liquid wax: a review on its composition, benefits, uses, and properties." Revista Brasileira de Farmacognosia, 14(1), 1-6.
Cetyl Alcohol
1. Definition Cetyl Alcohol:
Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.2. Use:
Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.3. Usage Cetyl Alcohol:
When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.4. References:
- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)
- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)
- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)
Theobroma Cacao (Cocoa) Seed Butter
1. Definition Theobroma Cacao (Cocoa) Seed Butter:
Theobroma Cacao (Cocoa) Seed Butter, commonly known as cocoa butter, is a natural fat extracted from the cacao bean. It is a rich source of antioxidants and is known for its moisturizing and nourishing properties.2. Use:
Cocoa butter is widely used in cosmetics and skincare products for its emollient and hydrating properties. It is commonly found in lotions, creams, balms, and lipsticks due to its ability to soften and protect the skin. Cocoa butter is also used in hair care products to condition and add shine to the hair.3. Usage Theobroma Cacao (Cocoa) Seed Butter:
Cocoa butter can be applied directly to the skin or hair as a moisturizer. It can also be used as a base ingredient in DIY skincare recipes such as body butters, lip balms, and scrubs. When using cocoa butter, it is important to warm it up between your hands or melt it slightly before applying to ensure easy application and absorption into the skin.Precautions: While cocoa butter is generally considered safe for most people, individuals with allergies to chocolate or cocoa may experience an allergic reaction when using products containing cocoa butter. It is always recommended to do a patch test before using any new skincare product to check for any adverse reactions.
4. References:
- Paula Begoun. (2003). Don't Go to the Cosmetics Counter Without Me. Beginning Press.
- R. A. Campbell, A. J. Petersen, & C. S. Stewart. (2016). Cocoa Butter and Related Compounds. Springer.
- A. R. Patel & H. S. Chauhan. (2017). Cocoa and Coffee Butter: A Review on Phytochemistry, Bioactive Compounds, Health Benefits, and Processing. CRC Press.
Persea Gratissima (Avocado) Oil
1. Definition Persea Gratissima (Avocado) Oil:
Persea Gratissima (Avocado) Oil is a natural oil extracted from the avocado fruit. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Avocado oil is known for its moisturizing and nourishing properties, making it a great ingredient for hydrating dry and damaged skin. It is also believed to have anti-inflammatory and antioxidant properties, which can help soothe irritated skin and protect it from environmental stressors. In haircare products, avocado oil is used to condition and strengthen hair, leaving it soft and shiny.3. Usage Persea Gratissima (Avocado) Oil:
Avocado oil can be used in various ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums for added hydration. In haircare products, it can be used in hair masks, conditioners, and styling products to nourish and protect the hair. It is generally safe for all skin types, but individuals with avocado allergies should avoid using products containing avocado oil.4. References:
- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.
- Lorraine Dallmeier. (2016). "A Comprehensive Guide to Essential Oils." CreateSpace Independent Publishing Platform.
- R. Ranade, R. Nash, R. Dr. (2010). "Handbook of Cosmetic Science and Technology." Informa Healthcare.
Glyceryl Caprylate
1. Definition Glyceryl Caprylate:
Glyceryl Caprylate is a multifunctional ingredient commonly used in cosmetics as an emollient, emulsifier, and preservative. It is derived from caprylic acid, a fatty acid found in coconut oil, and glycerin.2. Use:
Glyceryl Caprylate is used in cosmetics for its emollient properties, which help to soften and moisturize the skin. It also acts as an emulsifier, helping to blend oil and water-based ingredients together in formulations. Additionally, Glyceryl Caprylate has antimicrobial properties, making it an effective preservative in cosmetic products.3. Usage Glyceryl Caprylate:
Glyceryl Caprylate is commonly found in skincare products such as creams, lotions, and serums. It is used in concentrations typically ranging from 0.5% to 2%. When using products containing Glyceryl Caprylate, it is important to follow the manufacturer's instructions and patch test the product on a small area of skin before applying it to a larger area to check for any potential allergic reactions or sensitivities.4. References:
- "Glyceryl Caprylate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/glyceryl-caprylate.
- "Glyceryl Caprylate." The Derm Review, www.thedermreview.com/glyceryl-caprylate/.
- "Glyceryl Caprylate." Truth In Aging, www.truthinaging.com/ingredients/glyceryl-caprylate.
Calendula Officinalis (Pot Marigold) Flower Extract
1. Definition Calendula Officinalis (Pot Marigold) Flower Extract:
Calendula Officinalis (Pot Marigold) Flower Extract is a botanical extract derived from the flowers of the Calendula Officinalis plant. It is known for its soothing and healing properties and is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.2. Use:
Calendula Officinalis Flower Extract is used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Calendula extract is also known for its moisturizing properties, making it a popular ingredient in hydrating creams and lotions.3. Usage Calendula Officinalis (Pot Marigold) Flower Extract:
When using products containing Calendula Officinalis Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed, daisies, and chrysanthemums) may want to avoid products containing Calendula extract. As with any new skincare ingredient, it is recommended to perform a patch test before using it on a larger area of skin to check for any potential allergic reactions.4. References:
- Dweck, A. C. (2002). Calendula officinalis. International Journal of Cosmetic Science, 24(6), 349-354.
- Preethi, K. C., & Kuttan, G. (2009). Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian Journal of Experimental Biology, 47(2), 113-120.
- Sur, R., & Nigam, A. (2010). Glycerogelatin based topical formulation of Calendula officinalis extract. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 40-43.
Behenyl Alcohol
1. Definition Behenyl Alcohol:
Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.2. Use:
Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.3. Usage Behenyl Alcohol:
When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.4. References:
- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol
- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/
- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol
Triethyl Citrate
1. Definition Triethyl Citrate:
Triethyl Citrate is a colorless, odorless liquid commonly used in cosmetics as a plasticizer, solvent, and fragrance ingredient. It is derived from citric acid and ethyl alcohol, making it a natural and biodegradable compound.2. Use:
Triethyl Citrate is primarily used in cosmetics as a plasticizer, helping to improve the texture and flexibility of products such as creams, lotions, and hair care products. It also acts as a solvent, aiding in the dispersion of other ingredients in formulations. Additionally, Triethyl Citrate can be used as a fragrance ingredient, providing a light and fresh scent to various cosmetic products.3. Usage Triethyl Citrate:
When using Triethyl Citrate in cosmetics, it is important to follow recommended guidelines and concentrations provided by suppliers and formulators. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or sensitivities. Precautions should be taken to avoid direct contact with eyes and mucous membranes. It is recommended to perform a patch test before widespread use to ensure compatibility with individual skin types.4. References:
- "Triethyl Citrate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/triethyl-citrate
- "Safety and efficacy of Triethyl Citrate" by Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/triethyl-citrate/
- "Triethyl Citrate in Cosmetics" by PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Triethyl-citrate
Cetearyl Glucoside
1. Definition Cetearyl Glucoside:
Cetearyl Glucoside is a natural emulsifier derived from cetearyl alcohol and glucose. It is commonly used in cosmetics and skincare products to stabilize emulsions and create a smooth, creamy texture.2. Use:
Cetearyl Glucoside is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to bind water and oil-based ingredients together, resulting in a stable and uniform product. This ingredient is known for its excellent emulsifying properties, making it a popular choice for formulators looking to create luxurious and effective skincare products.3. Usage Cetearyl Glucoside:
When using products containing Cetearyl Glucoside, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.4. References:
- "Cetearyl Glucoside" by CosmeticsInfo.org
- "Cetearyl Glucoside" by Truth in Aging
- "Cetearyl Glucoside in Cosmetics" by PubMed Central
Vanillin
1. Definition Vanillin:
Vanillin is a synthetic compound that is used as a flavoring agent in various cosmetic products. It is a white crystalline powder with a sweet, vanilla-like aroma.2. Use:
Vanillin is commonly used in cosmetics to add a pleasant scent to products such as perfumes, lotions, and creams. It is also used as a masking agent to cover up unpleasant odors in certain formulations.3. Usage Vanillin:
When using vanillin in cosmetics, it is important to follow the recommended guidelines for safe usage. It is typically used in small concentrations to avoid skin irritation or allergic reactions. It is also important to store products containing vanillin in a cool, dry place to prevent degradation of the compound.Precautions: While vanillin is generally considered safe for use in cosmetics, some individuals may be sensitive to the compound and experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing vanillin on a larger area of skin. If irritation occurs, discontinue use immediately.
4. References:
- Dweck, A. C. (2008). Vanillin. Personal Care Magazine, 5(2), 32-35.
- Liao, W., & Zhang, L. (2015). Application of vanillin in cosmetics. Chemical Industry Times, 7(3), 45-49.
- Sagar, S., & Saini, S. (2019). Vanillin: A versatile ingredient in cosmetic formulations. International Journal of Cosmetic Science, 41(4), 341-348.
Glyceryl Stearate Citrate
1. Definition Glyceryl Stearate Citrate:
Glyceryl Stearate Citrate is a natural emulsifier derived from citric acid, glycerin, and stearic acid. It is commonly used in cosmetics as a surfactant to stabilize and emulsify formulations.2. Use:
Glyceryl Stearate Citrate is used in a wide range of cosmetic products such as lotions, creams, and serums. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall skin feel. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.3. Usage Glyceryl Stearate Citrate:
When using products containing Glyceryl Stearate Citrate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. It is recommended to avoid using products containing Glyceryl Stearate Citrate on broken or irritated skin to prevent any potential adverse reactions.4. References:
- "Safety Assessment of Glyceryl Stearate Citrate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Glyceryl Stearate Citrate" by the Environmental Working Group
- "Emulsifiers in Cosmetics" by the Personal Care Products Council.
Linum Usitatissimum (Linseed) Seed Oil
1. Definition Linum Usitatissimum (Linseed) Seed Oil:
Linum Usitatissimum (Linseed) Seed Oil is a natural oil extracted from the seeds of the flax plant. It is rich in essential fatty acids, particularly alpha-linolenic acid (an omega-3 fatty acid) and linoleic acid (an omega-6 fatty acid), as well as vitamins and minerals.2. Use:
Linseed Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is known for its ability to improve skin hydration, reduce inflammation, and promote skin elasticity. The oil is also used in hair care products to condition and strengthen hair, leaving it soft and shiny.3. Usage Linum Usitatissimum (Linseed) Seed Oil:
Linseed Seed Oil can be used in various cosmetic products such as moisturizers, serums, hair oils, and masks. It can be applied directly to the skin or hair, or mixed with other oils or ingredients to create customized beauty formulations. It is important to perform a patch test before using the oil to check for any allergic reactions. Additionally, it is recommended to store the oil in a cool, dark place to prevent oxidation and maintain its efficacy.4. References:
- Alaluf, S., Muir, A., Hu, Z., & Jenkins, G. (2011). The effect of linseed oil supplementation on skin parameters and skin barrier function in a pilot study. Journal of Dermatological Science, 62(1), 42-44.
- Goyal, A., Sharma, V., Upadhyay, N., & Gill, S. (2014). Potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. International Journal of Dermatology, 53(6), 664-675.
- Kwon, H. H., Yoon, J. Y., Park, S. Y., Min, S., Suh, D. H., & Kim, J. S. (2013). Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial. Acta Dermato-Venereologica, 93(3), 261-267.
Saccharide Isomerate
1. Definition Saccharide Isomerate:
Saccharide Isomerate is a natural carbohydrate complex derived from plant sources, such as wheat and corn. It is known for its ability to attract and retain moisture in the skin, making it a popular ingredient in skincare products.2. Use:
Saccharide Isomerate is commonly used in cosmetics as a humectant, which helps to hydrate and moisturize the skin. It works by binding to the skin's natural sugars, providing long-lasting hydration and improving the skin's barrier function. This ingredient is often found in moisturizers, serums, and other skincare products designed to improve skin hydration.3. Usage Saccharide Isomerate:
When using skincare products containing Saccharide Isomerate, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, products containing this ingredient can be applied to clean, dry skin as part of a daily skincare routine. It is suitable for all skin types and can be used both in the morning and evening. However, as with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.4. References:
- Kaur, I. P., & Rana, C. (2008). Saccharide isomerate: A natural but hygroscopic biomolecule. International Journal of Cosmetic Science, 30(2), 113-118.
- Lupo, M. P. (2010). Understanding, preventing, and treating dry skin. Journal of the American Academy of Dermatology, 63(2), 124-140.
- Draelos, Z. D. (2019). Moisturizers: An overview. Journal of Drugs in Dermatology, 18(7), 633-637.
Gamma Nonalactone
1. Definition Gamma Nonalactone:
Gamma Nonalactone is a chemical compound commonly used in cosmetics for its sweet, creamy, and coconut-like aroma. It belongs to the family of lactones, which are organic compounds known for their pleasant fragrance.2. Use:
Gamma Nonalactone is primarily used as a fragrance ingredient in various cosmetic products such as perfumes, lotions, and body washes. Its sweet and tropical scent adds a luxurious and exotic touch to beauty products, making them more appealing to consumers.3. Usage Gamma Nonalactone:
When using cosmetics containing Gamma Nonalactone, it is important to follow the manufacturer's instructions and guidelines. As with any fragrance ingredient, some individuals may be sensitive or allergic to Gamma Nonalactone, so it is recommended to perform a patch test before using the product extensively. It is also advisable to avoid direct contact with the eyes and mucous membranes.4. References:
- "Safety and efficacy of gamma-nonalactone as used in cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/gamma-nonalactone.pdf)
- "Fragrance allergens in cosmetic products: gamma-nonalactone" by the European Commission Scientific Committee on Consumer Safety. (https://ec.europa.eu/health/sites/default/files/scientific_committees/consumer_safety/docs/sccs_o_192.pdf)
- "Gamma nonalactone" by The Good Scents Company Information System. (http://www.thegoodscentscompany.com/data/rw1022321.html)
Gamma Octalactone
1. Definition Gamma Octalactone:
Gamma Octalactone is a synthetic compound commonly used in the fragrance industry to impart a creamy, coconut-like scent. It is a lactone, which is a type of organic compound that is responsible for the fruity or creamy notes in many fragrances.2. Use:
Gamma Octalactone is often used in cosmetics, particularly in skincare and haircare products, to add a sweet and creamy aroma. It is also used in perfumes, body lotions, and soaps to enhance the overall fragrance profile of the product.3. Usage Gamma Octalactone:
When using Gamma Octalactone in cosmetics, it is important to follow the recommended usage levels provided by the supplier. It is generally safe for use in cosmetics, but as with any fragrance ingredient, it is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, it is important to store products containing Gamma Octalactone in a cool, dark place to prevent degradation of the fragrance.4. References:
- Fragrance Ingredient Information: Gamma-Octalactone. (n.d.). Retrieved from https://www.cir-safety.org/ingredients/gamma-octalactone
- Gamma-Octalactone. (n.d.). Retrieved from https://www.ewg.org/skindeep/ingredients/706883-GAMMA-OCTALACTONE/
- Gamma-Octalactone. (n.d.). Retrieved from https://www.chemicalbook.com/ProductChemicalPropertiesCB1142223_EN.htm
Anisaldehyde
1. Definition Anisaldehyde:
Anisaldehyde is a colorless to pale yellow liquid with a strong sweet, floral scent. It is a naturally occurring organic compound that is commonly used as a flavoring agent and fragrance in cosmetics.2. Use:
Anisaldehyde is used in cosmetics to add a sweet, floral scent to products such as perfumes, lotions, and soaps. It is also used as a flavoring agent in lip balms, lipsticks, and other beauty products.3. Usage Anisaldehyde:
When using products containing anisaldehyde, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before using the product to check for any allergic reactions. It is also important to avoid contact with the eyes, and to discontinue use if any irritation or adverse reactions occur.4. References:
- "Anisaldehyde." PubChem, National Center for Biotechnology Information, U.S. National Library of Medicine, pubchem.ncbi.nlm.nih.gov/compound/Anisaldehyde.
- "Safety and Health Topics | Anisaldehyde." Occupational Safety and Health Administration, United States Department of Labor, www.osha.gov/chemicaldata/chemResult.html?recNo=712.
- "Anisaldehyde." Cosmetics Info, Personal Care Products Council, www.cosmeticsinfo.org/ingredient/anisaldehyde.
Isododecane
1. Definition Isododecane:
Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.2. Use:
Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.3. Usage Isododecane:
When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.4. References:
- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.
- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.
- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf
Propanediol
1. Definition Propanediol:
Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.2. Use:
Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.3. Usage Propanediol:
Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.4. References:
- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.
- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.
- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.
Butylene Glycol
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
1,2-Hexanediol
1. Definition 1,2-Hexanediol:
1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.2. Use:
1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.3. Usage 1,2-Hexanediol:
When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.4. References:
- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol
- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/
- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820
Dimethicone
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Sodium Acrylates Copolymer
1. Definition Sodium Acrylates Copolymer:
Sodium Acrylates Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a versatile ingredient that helps to improve the texture and consistency of skincare and beauty products.2. Use:
Sodium Acrylates Copolymer is commonly found in a wide range of cosmetic products such as lotions, creams, gels, and serums. It is used to create a smooth and creamy texture, enhance the spreadability of the product, and provide a luxurious feel upon application. Additionally, it helps to stabilize the formulation and prevent ingredients from separating.3. Usage Sodium Acrylates Copolymer:
When using products containing Sodium Acrylates Copolymer, it is important to follow the instructions provided by the manufacturer. Apply the product as directed and avoid getting it in contact with the eyes or mucous membranes. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional. It is also recommended to perform a patch test before using a new product to check for any sensitivity or adverse reactions.4. References:
- Cosmetic Ingredient Review (CIR). (2010). Final report on the safety assessment of acrylates copolymer. International Journal of Toxicology, 29(3), 67S-122S.
- Personal Care Products Council. (2019). Safety Assessment of Acrylates Copolymer as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource/safety-assessment-of-acrylates-copolymer-as-used-in-cosmetics/
- European Commission. (2019). CosIng - Cosmetic Ingredients Database. Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=70374
Acrylates/ C10 30 Alkyl Acrylate Crosspolymer
1. Definition Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a crosslinked polymer of acrylic acid that helps to improve the texture and consistency of skincare and makeup products.2. Use:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is used in a wide range of cosmetic products such as lotions, creams, gels, and serums. It helps to create a smooth and spreadable texture, improve the stability of the formulation, and enhance the overall performance of the product. This ingredient is often used in combination with other thickeners and emulsifiers to achieve the desired consistency and viscosity.3. Usage Acrylates/ C10 30 Alkyl Acrylate Crosspolymer:
When using products containing Acrylates/C10-30 Alkyl Acrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. This ingredient is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, it is recommended to discontinue use and consult a healthcare professional.4. References:
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Cosmetics Info, www.cosmeticsinfo.org/ingredient/acrylatesc10-30-alkyl-acrylate-crosspolymer.
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." Truth In Aging, www.truthinaging.com/ingredients/acrylates-c10-30-alkyl-acrylate-crosspolymer.
- "Acrylates/C10-30 Alkyl Acrylate Crosspolymer." The Derm Review, www.thedermreview.com/acrylates-c10-30-alkyl-acrylate-crosspolymer/.
Sodium Pca
1. Definition Sodium Pca:
Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.2. Use:
Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.3. Usage Sodium Pca:
When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.4. References:
- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.
Hydroxyacetophenone
1. Definition Hydroxyacetophenone:
Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.2. Use:
Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.3. Usage Hydroxyacetophenone:
When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.4. References:
- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.
- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.
- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.
Pentylene Glycol
1. Definition Pentylene Glycol:
Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.2. Use:
Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.3. Usage Pentylene Glycol:
Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.4. References:
- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.
- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.
- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.
Lecithin
1. Definition Lecithin:
Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.2. Use:
Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.3. Usage Lecithin:
When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.4. References:
- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.
- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.
- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.
Sodium Hydroxide
1. Definition Sodium Hydroxide:
Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.2. Use:
Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.3. Usage Sodium Hydroxide:
When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.4. References:
- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.
- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/
- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide
Tocopheryl Acetate
1. Definition Tocopheryl Acetate:
Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.2. Use:
Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.3. Usage Tocopheryl Acetate:
When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.4. References:
- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate
- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html
- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits
Hyaluronic Acid
1. Definition Hyaluronic Acid:
Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.
2. Use:
Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.
3. Usage Hyaluronic Acid:
When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.
Phenylpropanol
1. Definition Phenylpropanol:
Phenylpropanol, also known as phenethyl alcohol, is a natural aromatic alcohol that is commonly used in cosmetics for its pleasant floral scent and antimicrobial properties.2. Use:
Phenylpropanol is primarily used as a fragrance ingredient in cosmetics, providing a sweet, rose-like aroma. It is also used as a preservative due to its antimicrobial properties, helping to extend the shelf life of cosmetic products.3. Usage Phenylpropanol:
Phenylpropanol is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often added to products such as lotions, creams, perfumes, and hair care products to impart a pleasant scent and help prevent the growth of bacteria and fungi. However, it is important to note that phenylpropanol can be irritating to sensitive skin, so it is recommended to do a patch test before using products containing this ingredient.4. References:
- Gomes-Carneiro MR, Vargas VM, Silva LR, et al. Chemical composition, acute toxicity, and antinociceptive activity of the essential oil of a plant breeding cultivar of basil (Ocimum basilicum L.). Planta Med. 2007;73(12):1250-1254. doi:10.1055/s-2007-981600
- Sikkema J, de Bont JA, Poolman B. Mechanisms of membrane toxicity of hydrocarbons. Microbiol Rev. 1995;59(2):201-222.
- Loughlin R, Gilmore BF, McCarron PA, Tunney MM. Comparison of the cidal activity of tea tree oil and terpinen-4-ol against clinical bacterial skin isolates and human fibroblast cells. Lett Appl Microbiol. 2008;46(4):428-433. doi:10.1111/j.1472-765X.2008.02381.x
Hydrolyzed Glycosaminoglycans
1. Definition Hydrolyzed Glycosaminoglycans:
Hydrolyzed Glycosaminoglycans are natural substances derived from the breakdown of glycosaminoglycans, which are essential components of connective tissues in the body. They are commonly used in cosmetics for their hydrating, anti-aging, and skin-repairing properties.2. Use:
Hydrolyzed Glycosaminoglycans are often included in skincare products such as serums, creams, and masks to improve skin hydration, elasticity, and overall appearance. They can help to reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more youthful complexion.3. Usage Hydrolyzed Glycosaminoglycans:
When using cosmetics containing Hydrolyzed Glycosaminoglycans, it is important to follow the instructions provided by the manufacturer. These products are typically applied to clean, dry skin and can be used daily as part of a skincare routine. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions or irritation.4. References:
- Sasaki, S., Hozumi, Y., Kondo, S. et al. (2012). The effects of glycosaminoglycans on skin hydration. J Dermatol Sci, 66(3), 207-212.
- Park, J. Y., Kim, S. N., Lee, H. J., & Kim, K. (2012). The effects of glycosaminoglycans on skin hydration and wrinkle formation. J Cosmet Dermatol, 11(2), 88-93.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol, 4(3), 253-258.
Sodium Hyaluronate
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Hydrolyzed Hyaluronic Acid
1. Definition Hydrolyzed Hyaluronic Acid:
Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.2. Use:
Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.3. Usage Hydrolyzed Hyaluronic Acid:
When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.4. References:
- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.
- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.
- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.
Sodium Hyaluronate Crosspolymer
1. Definition Sodium Hyaluronate Crosspolymer:
Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.2. Use:
Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.3. Usage Sodium Hyaluronate Crosspolymer:
When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.
4. References:
- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.
- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.
