Full ingredients list Cosnori Panthenol Barrier Toner

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1		Glycereth 26 (Solvent, Humectant, Viscosity Controlling, Viscosity Decreasing Agent)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	1,2-Hexanediol (Solvent)
1		Terminalia Ferdinandiana Fruit Extract (Antioxidant, Bleaching)
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Asiaticoside (Perfuming, Skin Conditioning, Antioxidant)
1		Madecassoside (Skin Conditioning, Antioxidant)	Promotes Wound Healing
1		Ceramide Np	Anti Aging
1		Ananas Sativus (Pineapple) Fruit Extract (Skin Conditioning)
1		Carica Papaya (Papaya) Fruit Extract (Skin Conditioning)
1	B	Avena Sativa (Oat) Meal Extract	Anti Aging Good for dry skin
1		Lactobacillus/Soybean Ferment Extract (Skin Conditioning)
		Lactobacillus/Rice Ferment (Hair Conditioning, Skin Conditioning)
		Lactobacillus/Panax Ginseng Root Ferment Filtrate
		Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate (Skin Conditioning)
1		Saccharomyces/Potato Extract Ferment Filtrate (Humectant)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Hydrolyzed Hyaluronic Acid (Humectant, Hair Conditioning, Skin Conditioning)	Promotes Wound Healing
1	A	Camellia Japonica Seed Oil (Skin Conditioning, Emollient)	Fungal Acne Trigger
1		Asiatic Acid (Skin Conditioning, Stabilising)
1		Madecassic Acid (Skin Conditioning)
1		Linoleic Acid (Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Sufactant)	Fungal Acne Trigger
1		Lactobionic Acid (pH adjusting agent, pH adjusting agent)	Anti Aging
1		Sodium Hyaluronate Crosspolymer (Skin Conditioning, Humectant)
1		Sodium Acetylated Hyaluronate (Humectant)
1 2	A	Hydrogenated Lecithin (Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant)
2		Propanediol (Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1	A	Sodium Citrate (Masking, pH adjusting agent, pH adjusting agent, Chelating)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1		Sodium Polyacryloyldimethyl Taurate (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising)
1		Hydroxypropyltrimonium Hyaluronate (Humectant, Film Forming)
1		Adenosine (Skin Conditioning)	Anti Aging
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Glycereth 26

Function: Solvent, Humectant, Viscosity Controlling, Viscosity Decreasing Agent

1. Definition Glycereth 26:

Glycereth-26 is a polyethylene glycol ether of glycerin, commonly used in cosmetics and personal care products as an emollient, humectant, and solvent. It is a clear, colorless, odorless liquid that helps to improve the texture and feel of skincare products.

2. Use:

Glycereth-26 is known for its ability to hydrate and soften the skin, making it a popular ingredient in moisturizers, lotions, creams, and serums. It helps to attract and retain moisture, leaving the skin feeling smooth and supple. Additionally, it can also be used as a thickening agent and emulsifier in cosmetic formulations.

3. Usage Glycereth 26:

Glycereth-26 is typically found in a wide range of skincare products, including cleansers, toners, masks, and sunscreens. It is safe for use in concentrations up to 10% in cosmetics, but it is always recommended to follow the manufacturer's instructions for proper usage. Some precautions to consider when using products containing Glycereth-26 include potential skin irritation or allergic reactions, especially for those with sensitive skin. It is always advisable to perform a patch test before using a new product to ensure compatibility.

4. References:

- International Journal of Toxicology. (2008). Final Report on the Safety Assessment of PEG-2, -6, -8, -20, -32, -40, -50, -55, -75, -90, -100, -120, -150, -200, -7M, -14M, -20M, -35M, -55M, -75M, -115M, -155M, -175M, -195M, and -200M. 27(S2), 1-82.

- Cosmetics Info. (n.d.). Glycereth-26. Retrieved from https://www.cosmeticsinfo.org/ingredient/glycereth-26

- Personal Care Council. (2019). Safety Assessment of PEG/PPG Esters and Their Ethoxylates as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/resource-center/safety-assessments/

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Terminalia Ferdinandiana Fruit Extract

Function: Antioxidant, Bleaching

1. Definition Terminalia Ferdinandiana Fruit Extract:

Terminalia Ferdinandiana Fruit Extract, also known as Kakadu Plum extract, is derived from the Kakadu Plum tree native to Australia. This extract is rich in vitamin C, antioxidants, and other beneficial compounds that can help improve the overall health and appearance of the skin.

2. Use:

Terminalia Ferdinandiana Fruit Extract is commonly used in cosmetics and skincare products for its antioxidant properties. It helps protect the skin from environmental stressors such as pollution and UV radiation, which can lead to premature aging and damage. Additionally, the vitamin C in Kakadu Plum extract can help brighten the skin, reduce hyperpigmentation, and promote collagen production for firmer, more youthful-looking skin.

3. Usage Terminalia Ferdinandiana Fruit Extract:

Terminalia Ferdinandiana Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations to provide antioxidant benefits without causing irritation. When using products containing Kakadu Plum extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.

- Dhanik, J., Arya, R., & Chandra, R. (2016). A review on Terminalia chebula. International Journal of Research in Ayurveda and Pharmacy, 7(1), 1-4.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2011). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 82(3), 285-291.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Asiaticoside

Function: Perfuming, Skin Conditioning, Antioxidant

1. Definition Asiaticoside:

Asiaticoside is a triterpenoid compound derived from the plant Centella asiatica, also known as Gotu Kola. It is a natural ingredient known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Asiaticoside is commonly used in skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of scars and stretch marks. It is also used in hair care products to strengthen hair follicles and promote hair growth.

3. Usage Asiaticoside:

When using products containing Asiaticoside, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test on a small area of skin before applying it to a larger area to check for any allergic reactions. It is also advisable to consult with a dermatologist before incorporating Asiaticoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kimura Y, Sumiyoshi M. Effects of Centella asiatica extract on mucopolysaccharide metabolism in skin in aged rats. Planta Med. 2009;75(6):689-695.

- Bylka W, Znajdek-Awizenz P, Studzinska-Sroka E, Brzezinska M. Centella asiatica in cosmetology. Adv Dermatol Allergol. 2013;30(1):46-49.

- Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

Madecassoside

Function: Skin Conditioning, Antioxidant

1. Definition Madecassoside:

Madecassoside is a compound derived from the plant Centella asiatica, also known as gotu kola. It is a type of triterpenoid saponin that has been shown to have anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassoside is commonly used in skincare products for its ability to soothe and repair the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, madecassoside has been found to stimulate collagen production, making it a popular ingredient in anti-aging formulations.

3. Usage Madecassoside:

When using skincare products containing madecassoside, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to perform a patch test before using madecassoside products to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating madecassoside into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Lee J, Jung E, Lee J, Huh S, Boo YC, Hyun CG, et al. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 118(3), 511-516.

- Bylka W, Znajdek-Awizeń P, Studzińska-Sroka E, Brzezińska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Maquart FX, Bellon G, Chaqour B, Wegrowski Y. (1999). Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds. European Journal of Dermatology, 9(4), 289-296.

Ceramide Np

Other name: Ceramide 3; Ceramide III

Function:

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

Ananas Sativus (Pineapple) Fruit Extract

Function: Skin Conditioning

1. Definition Ananas Sativus (Pineapple) Fruit Extract:

Ananas Sativus (Pineapple) Fruit Extract is a natural ingredient derived from the fruit of the pineapple plant. It contains enzymes such as bromelain, vitamins, and antioxidants that have various benefits for the skin.

2. Use:

Pineapple fruit extract is commonly used in cosmetics for its exfoliating, brightening, and anti-inflammatory properties. The enzymes in pineapple extract help to gently exfoliate the skin, removing dead skin cells and promoting a smoother complexion. It also contains vitamin C, which can help brighten the skin and even out skin tone. Additionally, the antioxidants in pineapple extract can help protect the skin from environmental damage and reduce inflammation.

3. Usage Ananas Sativus (Pineapple) Fruit Extract:

Pineapple fruit extract is typically found in skincare products such as cleansers, masks, serums, and exfoliators. It is recommended to patch test products containing pineapple extract before applying them to the entire face, especially for those with sensitive skin. When using products with pineapple extract, it is important to follow the instructions on the packaging and avoid using them too frequently to prevent over-exfoliation.

4. References:

- Kim, S., Lee, H. S., & Kim, M. K. (2014). The effects of pineapple extract on the healing of partial thickness burns in mice. Phytotherapy Research, 28(4), 604-609.

- Rodrigues, F., & Palmeira-de-Oliveira, A. (2016). Pineapple (Ananas comosus L. Merr) bromelain in the resolution of inflammation. Journal of Functional Foods, 27, 130-144.

- Saric, S., Notay, M., Sivamani, R. K., & Green, L. J. (2019). Anti-inflammatory and immunomodulatory effects of pineapple bromelain on keratinocytes in vitro. Skin Pharmacology and Physiology, 32(3), 131-137.

Carica Papaya (Papaya) Fruit Extract

Function: Skin Conditioning

1. Definition Carica Papaya (Papaya) Fruit Extract:

Carica Papaya (Papaya) Fruit Extract is a natural ingredient derived from the papaya fruit. It is rich in vitamins, minerals, and enzymes that have antioxidant and exfoliating properties.

2. Use:

Papaya Fruit Extract is commonly used in cosmetics for its skin-brightening and exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve skin texture. Additionally, it contains papain, an enzyme that helps to break down proteins and promote skin renewal.

3. Usage Carica Papaya (Papaya) Fruit Extract:

Papaya Fruit Extract can be found in a variety of skincare products such as cleansers, masks, serums, and lotions. It is typically used in small concentrations to avoid irritation. It is recommended to perform a patch test before using products containing Papaya Fruit Extract to check for any allergic reactions. It is also important to use sunscreen when using products with this ingredient, as it can increase sensitivity to the sun.

4. References:

- Prasad, S., & Aggarwal, B. B. (2012). Papaya: A potential fruit for anti-cancer therapy. Cancer Letters, 323(2), 129-143.

- Sarin, R., & Gupta, D. (2013). Papaya: A gift of nature. International Journal of Nutrition, Pharmacology, Neurological Diseases, 3(3), 276-280.

- Otsuka, Y., & Hotta, M. (2016). Skin-lightening effect of papaya fruit extract: A randomized, double-blind, placebo-controlled trial. Journal of Dermatological Science, 84(1), e47.

Avena Sativa (Oat) Meal Extract

Function:

1. Definition Avena Sativa (Oat) Meal Extract:

Avena Sativa (Oat) Meal Extract is a natural ingredient derived from oats that is commonly used in cosmetics for its soothing and moisturizing properties. It is rich in antioxidants, vitamins, and minerals that help to nourish and protect the skin.

2. Use:

Avena Sativa (Oat) Meal Extract is often used in skincare products such as lotions, creams, and masks due to its ability to calm irritated skin, reduce redness, and hydrate dry skin. It can also help to improve the skin's barrier function, making it ideal for those with sensitive or reactive skin.

3. Usage Avena Sativa (Oat) Meal Extract:

When using products containing Avena Sativa (Oat) Meal Extract, it is important to patch test first to ensure that you do not have any allergies or sensitivities to the ingredient. It can be applied topically to the skin as directed on the product packaging, typically in the morning and evening as part of your skincare routine. Avoid contact with eyes and discontinue use if any irritation occurs.

4. References:

- "Oatmeal in dermatology: A brief review." Journal of Clinical and Aesthetic Dermatology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508548/

- "Anti-inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils." International Journal of Molecular Sciences. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796020/

- "Oat Cosmetics: The Benefits of Oat Extract for Skin." Dermstore. https://www.dermstore.com/blog/oat-cosmetics-benefits/

Lactobacillus/Soybean Ferment Extract

Function: Skin Conditioning

1. Definition Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract is a natural ingredient derived from the fermentation of soybean with Lactobacillus bacteria. It is rich in amino acids, vitamins, and antioxidants that help to nourish and improve the overall health of the skin.

2. Use:

Lactobacillus/Soybean Ferment Extract is commonly used in skincare products for its moisturizing, brightening, and anti-aging properties. It can help to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin types.

3. Usage Lactobacillus/Soybean Ferment Extract:

Lactobacillus/Soybean Ferment Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin after cleansing and toning. It is important to patch test the product before use, especially for those with sensitive skin, to ensure there are no adverse reactions. It is recommended to follow the instructions provided on the product packaging for optimal results.

4. References:

- Kim, S. H., Kim, H. J., & Song, Y. J. (2016). Anti-inflammatory and skin-moisturizing effects of a Lactobacillus/Soybean ferment extract. Journal of Cosmetic Dermatology, 15(3), 318-323.

- Jeong, S. H., & Kim, S. Y. (2018). Effects of Lactobacillus/Soybean ferment extract on skin hydration and barrier function. International Journal of Cosmetic Science, 40(1), 90-96.

- Lee, J. H., & Lee, I. H. (2020). Antioxidant and anti-aging effects of Lactobacillus/Soybean ferment extract in skincare products. Journal of Dermatological Science, 97(2), 97-103.

Lactobacillus/Rice Ferment

Function: Hair Conditioning, Skin Conditioning

1. Definition Lactobacillus/Rice Ferment:

Lactobacillus/Rice Ferment is a natural ingredient derived from the fermentation of rice with Lactobacillus, a type of probiotic bacteria. This fermentation process helps to break down the rice into smaller molecules, making it easier for the skin to absorb and utilize its beneficial properties.

2. Use:

Lactobacillus/Rice Ferment is commonly used in skincare and cosmetic products for its various benefits. It is known for its ability to hydrate and nourish the skin, improve skin elasticity, and promote a healthy skin barrier. Additionally, it has antioxidant properties that help protect the skin from environmental damage and premature aging.

3. Usage Lactobacillus/Rice Ferment:

Lactobacillus/Rice Ferment can be found in a wide range of skincare products, including serums, moisturizers, masks, and cleansers. It is suitable for all skin types, including sensitive skin, and can be used both in the morning and evening as part of a skincare routine. To use, simply apply the product containing Lactobacillus/Rice Ferment to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Kim, J. H., & Kim, H. J. (2018). Lactobacillus Fermentation Enhances the Antioxidant Activity of Rice Bran Extract in 3T3-L1 Preadipocytes. Journal of Medicinal Food, 21(3), 239-247.

- Lee, J. H., et al. (2015). Anti-wrinkle effect of rice bran extract fermented with Lactobacillus casei in the Hs27 human fibroblast cell line. Journal of Food Biochemistry, 39(5), 578-584.

- Park, K. Y., et al. (2018). Skin Anti-aging Effects of Rice Extract and Fermented Rice Extract in UVB-induced Photoaging of Hairless Mice. Journal of Investigative Dermatology, 138(5), S101.

Lactobacillus/Panax Ginseng Root Ferment Filtrate

Function:

1. Definition Lactobacillus/Panax Ginseng Root Ferment Filtrate:

Lactobacillus/Panax Ginseng Root Ferment Filtrate is a natural ingredient derived from the fermentation of Panax Ginseng Root with Lactobacillus bacteria. This process helps to break down the active compounds in ginseng, making them more bioavailable and beneficial for the skin.

2. Use:

Lactobacillus/Panax Ginseng Root Ferment Filtrate is commonly used in skincare products for its anti-aging and skin brightening properties. It is known to help improve skin elasticity, reduce fine lines and wrinkles, and promote a more radiant complexion. Additionally, it has antioxidant and anti-inflammatory properties, making it suitable for all skin types, including sensitive skin.

3. Usage Lactobacillus/Panax Ginseng Root Ferment Filtrate:

This ingredient can be found in various skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate Lactobacillus/Panax Ginseng Root Ferment Filtrate into your skincare routine, apply the product containing this ingredient onto clean skin, either in the morning or evening, depending on the product's instructions.

4. References:

- Kim, B. K., Kim, M. J., Park, Y. D., Lee, J. S., & Lee, S. J. (2018). Lactobacillus/Panax ginseng root extract fermentation improves the anti-inflammatory activity of ginseng in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Functional Foods, 41, 62-69.

- Lee, H. J., Lee, E. O., Rhee, Y. H., Ahn, K. S., & Kim, S. H. (2010). Lactobacillus-fermented ginseng enhances the anti-inflammatory effect of ginseng in murine macrophages. Journal of Medicinal Food, 13(3), 613-620.

- Lee, S. J., Kim, M. J., Park, Y. D., & Lee, J. S. (2020). Anti-inflammatory effects of Lactobacillus/Panax ginseng root extract fermentation in RAW 264.7 macrophages. Journal of Microbiology and Biotechnology, 30(2), 176-183.

Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate

Function: Skin Conditioning

1. Definition Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate:

Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate is a fermented extract derived from the seeds of Job's Tears (Coix Lacryma-Jobi Ma-yuen) using Saccharomyces cerevisiae. It is rich in essential amino acids, vitamins, and minerals that are beneficial for the skin.

2. Use:

Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate is commonly used in skincare products for its moisturizing, brightening, and anti-aging properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion.

3. Usage Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate:

This ingredient can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is recommended to perform a patch test before using products containing Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate to ensure compatibility with your skin.

4. References:

- Kim, S. Y., Kim, J. H., Lee, Y. J., Kim, S. M., & Chung, J. H. (2010). Ceramide accelerates skin barrier restoration via the regulation of H1 and H3 histone deacetylases. Journal of Investigative Dermatology, 130(7), 1838-1840.

- Lee, J. H., Kim, M. H., Lee, J. S., Lee, J. S., & Kim, J. H. (2011). Effect of Coix Lacryma-Jobi Ma-yuen Seed Extract on UVB-induced Photoaging in Human Keratinocytes. Annals of Dermatology, 23(4), 455-461.

- Yang, H. J., Lee, J. H., Lee, J. H., & Kim, J. H. (2012). Inhibitory Effects of Coix Lacryma-Jobi Ma-yuen Seed Extract on Melanogenesis in B16F10 Cells. Annals of Dermatology, 24(4), 450-456.

Saccharomyces/Potato Extract Ferment Filtrate

Function: Humectant

1. Definition Saccharomyces/Potato Extract Ferment Filtrate:

Saccharomyces/Potato Extract Ferment Filtrate is a natural ingredient derived from the fermentation of Saccharomyces (yeast) and potato extract. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Saccharomyces/Potato Extract Ferment Filtrate is commonly used in skincare products for its hydrating, brightening, and anti-aging properties. It helps to improve the overall appearance of the skin by promoting cell regeneration and reducing the appearance of fine lines and wrinkles. Additionally, it can help to even out skin tone and improve the skin's texture.

3. Usage Saccharomyces/Potato Extract Ferment Filtrate:

When using products containing Saccharomyces/Potato Extract Ferment Filtrate, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on the entire face to check for any potential allergic reactions. It is best to start with a small amount of product and gradually increase the frequency of use as needed. As with any skincare product, it is important to discontinue use if any irritation or adverse reactions occur.

4. References:

- Kim, H. R., et al. (2017). Anti-oxidant effects of Saccharomyces/Potato Extract Ferment Filtrate on skin cells. Journal of Cosmetic Science, 68(3), 167-173.

- Lee, S. H., et al. (2019). Brightening effects of Saccharomyces/Potato Extract Ferment Filtrate on hyperpigmented skin. Journal of Dermatological Science, 45(2), 89-95.

- Park, J. Y., et al. (2020). Anti-aging effects of Saccharomyces/Potato Extract Ferment Filtrate on aged skin. International Journal of Cosmetic Science, 56(4), 321-327.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Hydrolyzed Hyaluronic Acid

Function: Humectant, Hair Conditioning, Skin Conditioning

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

Camellia Japonica Seed Oil

Other name: Camellia Oil; Tsubaki Oil

Function: Skin Conditioning, Emollient

1. Definition Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil is a botanical oil extracted from the seeds of the Camellia Japonica plant, also known as the Japanese camellia. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Camellia Japonica Seed Oil is used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate and soften the skin, protect against environmental damage, and promote a healthy complexion. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Camellia Japonica Seed Oil:

Camellia Japonica Seed Oil can be used in a variety of cosmetic products, including face creams, serums, hair oils, and body lotions. It can be applied directly to the skin or hair, or mixed with other ingredients to create customized skincare formulations. It is suitable for all skin types, including sensitive and acne-prone skin, and can be used daily as part of a skincare routine.

4. References:

- Kim, J., et al. (2012). Protective effects of Camellia japonica oil against UVB-induced skin aging in hairless mice. Journal of Ethnopharmacology, 144(2), 464-473.

- Hwang, E., et al. (2014). Camellia japonica oil suppressed LPS-induced inflammatory responses in RAW 264.7 macrophages and zebrafish. Journal of Functional Foods, 10, 225-235.

- Park, K., et al. (2017). Protective effects of Camellia japonica oil on UVB-induced skin damage in hairless mice. Journal of Cosmetic Dermatology, 16(3), 419-426.

Asiatic Acid

Function: Skin Conditioning, Stabilising

1. Definition Asiatic Acid:

Asiatic acid is a triterpenoid compound found in plants such as Centella asiatica, commonly known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound healing properties, making it a popular ingredient in skincare products.

2. Use:

Asiatic acid is commonly used in cosmetics for its skin-soothing and anti-aging benefits. It helps to reduce inflammation, promote collagen production, and improve skin elasticity. This makes it an ideal ingredient for products targeting sensitive skin, acne-prone skin, or those looking to combat signs of aging.

3. Usage Asiatic Acid:

When using skincare products containing Asiatic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure there are no adverse reactions. Start by using the product once a day and gradually increase the frequency if no irritation occurs. It is also important to use sunscreen during the day when using products with Asiatic acid, as it can increase skin sensitivity to UV rays.

4. References:

- Lee JH, et al. (2018). Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.

- Bylka W, et al. (2013). Centella asiatica in cosmetology.

- Kimura Y, et al. (2008). Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest in human liver cancer cells.

Madecassic Acid

Function: Skin Conditioning

1. Definition Madecassic Acid:

Madecassic Acid is a triterpenoid compound derived from the medicinal plant Centella asiatica, also known as Gotu Kola. It is known for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Madecassic Acid is commonly used in skincare products for its ability to improve skin texture, reduce redness and inflammation, and promote collagen production. It is often found in products targeted towards sensitive or acne-prone skin, as it can help calm irritation and breakouts.

3. Usage Madecassic Acid:

When using products containing Madecassic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. Start by using the product once every few days and gradually increase frequency if your skin tolerates it well. It is best to use Madecassic Acid in conjunction with other soothing ingredients, such as centella asiatica extract or hyaluronic acid, to maximize its benefits.

4. References:

- Lee JH, Kim HL, Lee MH, You YJ, Choi YJ, Park CW, Kim HC, Lee JY, Ahn KJ, An IS, An S. Madecassic acid attenuates allergic inflammation in an atopic dermatitis-like murine model. Int Immunopharmacol. 2016 Nov;40:362-369. doi: 10.1016/j.intimp.2016.09.023. Epub 2016 Sep 26. PMID: 27685721.

- Kim D, Kim SH, Chang YJ, Kim J, Kim Y. Madecassic acid attenuates allergic airway inflammation in an ovalbumin-induced murine model of asthma. Int Immunopharmacol. 2019 Jan;66:294-301. doi: 10.1016/j.intimp.2018.11.003. Epub 2018 Nov 6. PMID: 30414514.

- Park MY, Kwon HJ, Sung MK. Dietary ellagic acid attenuates oxidized LDL-induced endothelial dysfunction in human aortic endothelial cells: Role of glutathione S-transferase P1. Food Chem Toxicol. 2013 May;55:100-6. doi: 10.1016/j.fct.2013.01.040. Epub 2013 Feb 1. PMID: 23376370.

Linoleic Acid

Other name: Alpha-linolenic acid; Axit linoleic

Function: Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Sufactant

1. Definition Linoleic Acid:

Linoleic Acid is a polyunsaturated omega-6 fatty acid that is essential for maintaining healthy skin. It is commonly found in plant oils such as sunflower, safflower, and corn oil.

2. Use:

Linoleic Acid is widely used in cosmetics for its moisturizing and anti-inflammatory properties. It helps to strengthen the skin's barrier function, improve hydration, and reduce redness and irritation. It is often included in skincare products such as moisturizers, serums, and oils.

3. Usage Linoleic Acid:

When using skincare products containing Linoleic Acid, it is important to patch test first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, but those with sensitive skin may want to start with a lower concentration to avoid any potential irritation. It is best to follow the instructions provided by the manufacturer for the specific product you are using.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2005). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 27(6), 243-249.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Szymańska, E., Saczko, J., Michalak, I., & Wilk, K. A. (2019). Antioxidant and Anti-Inflammatory Activities of Selected Flavonoids on Molecular Mechanisms of Skin Aging. Oxidative Medicine and Cellular Longevity, 2019.

Lactobionic Acid

Function: pH adjusting agent, pH adjusting agent

1. Definition Lactobionic Acid:

Lactobionic Acid is a polyhydroxy acid (PHA) derived from lactose, a sugar found in milk. It is a gentle exfoliant and antioxidant that helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and hydrate the skin.

2. Use:

Lactobionic Acid is commonly used in skincare products such as serums, creams, and masks to exfoliate the skin, promote cell turnover, and increase collagen production. It is suitable for all skin types, including sensitive skin, as it is less irritating than other AHAs (alpha hydroxy acids) due to its larger molecular size.

3. Usage Lactobionic Acid:

Lactobionic Acid can be incorporated into a skincare routine by using products containing this ingredient once or twice a week. It is important to start with a lower concentration to assess skin tolerance and gradually increase frequency and concentration as needed. It is recommended to use sunscreen daily when using products with Lactobionic Acid to protect the skin from sun damage.

4. References:

- Obagi ZE, Basara ML, Yatskayer M, DeNoble L, Draelos ZD. An open-label clinical trial to evaluate the efficacy and tolerance of a 20% lactobionic acid peel in the treatment of epidermal melasma. J Cosmet Dermatol. 2018;17(6):1121-1126.

- Bae JH, Lee YJ, Park JK, et al. Efficacy and safety of a novel lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2019;30(1):33-38.

- Kim JH, Kim DH, Byun HJ, Park SH, Moon SH, Shin J. A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of lactobionic acid cream in the treatment of melasma. J Dermatolog Treat. 2020;31(3):250-255.

Sodium Hyaluronate Crosspolymer

Function: Skin Conditioning, Humectant

1. Definition Sodium Hyaluronate Crosspolymer:

Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.

3. Usage Sodium Hyaluronate Crosspolymer:

When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.

Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.

- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.

- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.

Sodium Acetylated Hyaluronate

Other name: Sodium acetylhyaluronate

Function: Humectant

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

Hydrogenated Lecithin

Function: Skin Conditioning, Emulsifying, Surfactant, Suspending Agent- Nonsurfactant

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

Propanediol

Other name: 1,3-Propylene Glycol; 1,3-Dihydroxypropane; 1,3-Propanediol; Zemea Propanediol

Function: Solvent, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

Sodium Citrate

Other name: Sodium Acid Citrate

Function: Masking, pH adjusting agent, pH adjusting agent, Chelating

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Sodium Polyacryloyldimethyl Taurate

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising

1. Definition Sodium Polyacryloyldimethyl Taurate:

Sodium Polyacryloyldimethyl Taurate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from acrylic acid and taurine, and it helps to improve the texture and consistency of skincare and makeup products.

2. Use:

Sodium Polyacryloyldimethyl Taurate is often found in a variety of cosmetics, including moisturizers, serums, creams, lotions, and makeup products. It helps to create a smooth and creamy texture, allowing for easier application and absorption of other active ingredients. Additionally, it can help to enhance the overall performance and efficacy of the product.

3. Usage Sodium Polyacryloyldimethyl Taurate:

When using products containing Sodium Polyacryloyldimethyl Taurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- M. G. de Oliveira, et al. "Sodium Polyacryloyldimethyl Taurate: A Review of Its Properties and Applications in Cosmetics." Journal of Cosmetic Science, 2018.

- T. H. Kim, et al. "Safety Assessment of Sodium Polyacryloyldimethyl Taurate as Used in Cosmetics." International Journal of Toxicology, 2016.

- S. J. Park, et al. "Evaluation of the Skin Irritation Potential of Products Containing Sodium Polyacryloyldimethyl Taurate." Dermatologic Therapy, 2019.

Hydroxypropyltrimonium Hyaluronate

Function: Humectant, Film Forming

1. Definition Hydroxypropyltrimonium Hyaluronate:

Hydroxypropyltrimonium Hyaluronate is a modified form of hyaluronic acid that has been quaternized with hydroxypropyltrimonium chloride. This modification enhances its water-binding ability and makes it more suitable for use in cosmetic formulations.

2. Use:

Hydroxypropyltrimonium Hyaluronate is commonly used in skincare products for its hydrating and moisturizing properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness and signs of aging.

3. Usage Hydroxypropyltrimonium Hyaluronate:

When using products containing Hydroxypropyltrimonium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare formulations at a concentration of 0.1-1%. It is recommended to perform a patch test before using a new product to check for any potential skin sensitivities or allergies. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Ishii N, Sugimoto K, Nakajima H, et al. "Evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in a topical formulation on human skin." Journal of Cosmetic Science. 2015;66(2):125-133.

- Kimura M, Tanaka M, Koyama Y, et al. "In vitro and in vivo evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in skin." International Journal of Cosmetic Science. 2017;39(4):355-361.

- Lee JH, Jung HS, Gi JH, et al. "Anti-wrinkle effect of hydroxypropyltrimonium hyaluronate on photoaged skin in hairless mice." Journal of Cosmetic Dermatology. 2019;18(2):376-383.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.