Dermedicine Anti-aging Face Lift Cream

Dermedicine

INGREDIENTS

Water

Cetearyl Alcohol

Niacinamide

Polysorbate 60

Persea Gratissima (Avocado) Oil

Glycine Soja (Soybean) Oil

Glycerin

Dimethicone

Tocopherol (Vitamin E)

Hyaluronic Acid

Dimethyl Mea

Thioctic Acid

Saccharomyces/Copper Ferment

Carnitine

Sodium Ascorbyl Phosphate

Palmitoyl Tripeptide 5

Retinol

Acetyl Hexapeptide 8

Palmitoyl Tripeptide 1

Palmitoyl Tripeptide 37

Melatonin

Citrus Aurantium Amara (Bitter Orange) Flower Extract

Anthemis Nobilis (Chamomile) Extract

Salvia Officinalis (Sage) Extract

Citrus Aurantium Bergamia (Bergamot) Extract

Phenoxyethanol

Ethylhexylglycerin

Vitis Vinifera (Grape) Seed Oil

Ubiquinone

PRODUCT OVERVIEW

Quick product notes

(Click on icon for more information)

Quick product notes serve as a convenient method to determine if a product aligns with the preferences of skincare enthusiasts by being free from commonly avoided ingredients. These preferences arise due to various factors, including personal experiences, sensitivities, health considerations, and more.

Paraben free

Sulfate free

Alcohol free

Silicone free

Fungal Acne Safe

EU Allergent Free

Key Ingredients

Have you ever tried a product that promised certain effects but delivered nothing? It might have lacked key ingredients necessary for those promised results. Despite marketing claims, if a product lacks beneficial components, its efficacy is questionable.

We help you identify key ingredients known for effects such as acne-fighting, brightening, UV protection, and anti-aging, assisting you in making smarter skincare choices. Keep in mind that the effectiveness of key ingredients can vary; while some are well-proven, others have mixed research behind them.

Anti Aging from (5) Ingredient:

Sodium Ascorbyl Phosphate Ubiquinone Tocopherol (Vitamin E) Niacinamide Retinol

Promotes Wound Healing from (2) Ingredient:

Vitis Vinifera (Grape) Seed Oil Hyaluronic Acid

Brightening from (3) Ingredient:

Sodium Ascorbyl Phosphate Niacinamide Retinol

Acne fighting from (1) Ingredient:

Retinol

Ingredients Related to Skin Types

Click the arrows next to Skin Type! Green = Good & Red = Bad

Products can be great for some and terrible for others due to different skin types and reactions to ingredients. We've identified ingredients suitable for dry, oily, and sensitive skin types.

Dry skin

Persea Gratissima (Avocado) Oil

Low Risk

Tocopherol (Vitamin E)

Low Risk

Glycerin

Low Risk

Oily Skin

Glycine Soja (Soybean) Oil

High Risk

Persea Gratissima (Avocado) Oil

High Risk

Vitis Vinifera (Grape) Seed Oil

Low Risk

Sensitive skin

Retinol

High Risk

Oil skin

None

Ingredient Safety Breakdown (EWG Health Ratings)

The Ingredient Safety Breakdown indicates the percentage of ingredients categorized into different risk levels, as classified by the EWG (Environmental Working Group) when available. With numerous cosmetic ingredients in existence, the EWG is one of the few organizations globally that assigns ratings to many commonly used ingredients, making it a valuable reference point.

Low risk

Moderate risk

High risk

Unknown

79%

14%

INGREDIENT LIST

(Display the first 5 ingredients from a list of 29 ingredient)

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
3	B	Polysorbate 60 (Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Persea Gratissima (Avocado) Oil (Skin Conditioning)	Good for dry skin Bad for oily skin
1	A	Glycine Soja (Soybean) Oil (Fragrance, Skin Conditioning, Antioxidant, Emollient)	Bad for oily skin Fungal Acne Trigger
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1		Tocopherol (Vitamin E)	Good for dry skin Anti Aging
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
2 3		Dimethyl Mea (pH adjusting agent, pH adjusting agent)
1 2		Thioctic Acid (Antioxidant)
1		Saccharomyces/Copper Ferment (Skin Conditioning)
1	B	Carnitine (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting)
1	A	Sodium Ascorbyl Phosphate (Antioxidant)	Anti Aging Brightening
1		Palmitoyl Tripeptide 5 (Skin Conditioning)
9	A	Retinol (Skin Conditioning)	Anti Aging Bad for sensitive skin Brightening Acne fighting
1		Acetyl Hexapeptide 8 (Humectant, Skin Conditioning)
1	A	Palmitoyl Tripeptide 1 (Skin Conditioning)
1		Palmitoyl Tripeptide 37 (Skin Conditioning)
1		Melatonin (Antioxidant)
1		Citrus Aurantium Amara (Bitter Orange) Flower Extract (Skin-Conditioning Agent - Occlusive)
2		Anthemis Nobilis (Chamomile) Extract
1		Salvia Officinalis (Sage) Extract
		Citrus Aurantium Bergamia (Bergamot) Extract
2 4	A	Phenoxyethanol (Fragrance, Preservative)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Vitis Vinifera (Grape) Seed Oil (Skin Conditioning, Emollient)	Promotes Wound Healing Fungal Acne Trigger Good for oily skin
1		Ubiquinone (Skin Conditioning, Antioxidant)	Anti Aging

INGREDIENTS EXPLAINED Dermedicine Anti-aging Face Lift Cream

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Polysorbate 60

Other name: Tween 60; POE (20) Sorbitan monostearate; Polyoxyethylene (20) sorbitan monostearate

Function: Emulsifying, Surfactant

1. Definition Polysorbate 60:

Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.

2. Use:

Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.

3. Usage Polysorbate 60:

When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.

4. References:

- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.

- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.

- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.

Persea Gratissima (Avocado) Oil

Other name: Avocado Oil; Persea Gratissima Oil

Function: Skin Conditioning

1. Definition Persea Gratissima (Avocado) Oil:

Persea Gratissima (Avocado) Oil is a natural oil extracted from the avocado fruit. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Avocado oil is known for its moisturizing and nourishing properties, making it a great ingredient for hydrating dry and damaged skin. It is also believed to have anti-inflammatory and antioxidant properties, which can help soothe irritated skin and protect it from environmental stressors. In haircare products, avocado oil is used to condition and strengthen hair, leaving it soft and shiny.

3. Usage Persea Gratissima (Avocado) Oil:

Avocado oil can be used in various ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums for added hydration. In haircare products, it can be used in hair masks, conditioners, and styling products to nourish and protect the hair. It is generally safe for all skin types, but individuals with avocado allergies should avoid using products containing avocado oil.

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Lorraine Dallmeier. (2016). "A Comprehensive Guide to Essential Oils." CreateSpace Independent Publishing Platform.

- R. Ranade, R. Nash, R. Dr. (2010). "Handbook of Cosmetic Science and Technology." Informa Healthcare.

Glycine Soja (Soybean) Oil

Function: Fragrance, Skin Conditioning, Antioxidant, Emollient

1. Definition Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil is a natural oil derived from soybeans through a process of extraction. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Glycine Soja (Soybean) Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental stressors. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil can be found in a variety of cosmetic products such as moisturizers, serums, cleansers, hair masks, and conditioners. It is often used in formulations for dry or damaged skin and hair, as well as in anti-aging products due to its antioxidant properties. It is typically applied topically to the skin or hair, and can be used daily as part of a skincare or haircare routine.

4. References:

- Kim, S. Y., Kim, H. W., & Lee, S. H. (2018). Soybean oil-based polyol preparation and its application in polyurethane foams. Journal of Industrial and Engineering Chemistry, 64, 25-32.

- Reiter, M., Walfisz, A., & Wertz, J. (2016). Antioxidant potential of soybean oil enriched with phospholipids. Journal of the American Oil Chemists' Society, 93(2), 265-273.

- De Oliveira, D. M., Silva, R. C., & De Oliveira, L. E. (2015). Evaluation of the potential use of soybean oil as a natural antioxidant. Journal of Food Science and Technology, 52(5), 2808-2816.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Tocopherol (Vitamin E)

Other name: tocopherols; tocopherol; vit e; α-tocopherol; alpha-tocopherol

Function:

1. Definition Tocopherol (Vitamin E):

Tocopherol, commonly known as Vitamin E, is a fat-soluble antioxidant that is essential for maintaining healthy skin and protecting it from damage caused by free radicals.

2. Use:

Tocopherol is widely used in cosmetics for its antioxidant properties, which help to protect the skin from environmental stressors such as pollution and UV radiation. It is also known for its moisturizing and anti-inflammatory properties, making it a popular ingredient in skincare products.

3. Usage Tocopherol (Vitamin E):

Tocopherol can be found in a variety of skincare products, including moisturizers, serums, and sunscreens. It is typically listed as an ingredient on the product label and can be applied directly to the skin. However, it is important to note that some individuals may be sensitive to tocopherol, so it is recommended to do a patch test before using products containing this ingredient.

4. References:

- Lin, F.-H., Lin, J.-Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., … & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Thiele, J. J., Hsieh, S. N., Briviba, K., Sies, H. (1999). Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. Journal of Investigative Dermatology, 113(3), 335-339.

- Nachbar, F., Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of Molecular Medicine, 73(1), 7-17.

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Dimethyl Mea

Other name: DMAE; Dimethylamino ethanol; Deanol; Dimethyl MEA

Function: pH adjusting agent, pH adjusting agent

1. Definition Dimethyl Mea:

Dimethyl Mea, also known as dimethylaminoethanol or DMAE, is a compound that is commonly used in skincare products for its anti-aging properties. It is a derivative of the B vitamin choline and is naturally found in small amounts in the brain.

2. Use:

Dimethyl Mea is used in cosmetics for its ability to improve skin firmness and reduce the appearance of fine lines and wrinkles. It is often included in anti-aging serums, creams, and lotions to help promote a more youthful and radiant complexion.

3. Usage Dimethyl Mea:

When using skincare products containing Dimethyl Mea, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test on a small area of skin before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advised to start with a lower concentration of Dimethyl Mea and gradually increase the usage to assess how your skin reacts to the ingredient.

4. References:

- Perricone MD. (n.d.). DMAE. Retrieved from https://www.perriconemd.com/ingredients/dmae.html

- SkinCeuticals. (n.d.). Dimethyl Mea. Retrieved from https://www.skinceuticals.com/ingredient-science/dmae

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Professional.

Thioctic Acid

Other name: α-lipoic Acid; A-Lipoic Acid; Alpha Lipoic Acid

Function: Antioxidant

1. Definition Thioctic Acid:

Thioctic Acid, also known as Alpha Lipoic Acid (ALA), is a powerful antioxidant that is naturally found in the body. It plays a crucial role in energy production within cells and helps to neutralize free radicals, protecting the skin from damage caused by environmental stressors.

2. Use:

Thioctic Acid is commonly used in skincare products for its antioxidant properties. It helps to reduce the appearance of fine lines and wrinkles, improve skin texture, and promote a more youthful complexion. Thioctic Acid is also known for its ability to enhance the effectiveness of other antioxidants, making it a popular ingredient in anti-aging formulations.

3. Usage Thioctic Acid:

Thioctic Acid is typically found in serums, creams, and masks designed to target signs of aging and protect the skin from damage. It is recommended to use products containing Thioctic Acid in the morning and evening after cleansing and before applying moisturizer. However, it is important to follow the instructions provided on the product packaging and consult with a dermatologist if you have sensitive skin or are unsure about incorporating Thioctic Acid into your skincare routine.

4. References:

- Moini, H., Packer, L., & Saris, N. E. (2002). Antioxidant and prooxidant activities of α-lipoic acid and dihydrolipoic acid. Toxicology and Applied Pharmacology, 182(1), 84-90.

- Ziegler, D., Ametov, A., Barinov, A., Dyck, P. J., Gurieva, I., Low, P. A., ... & Samigullin, R. (2006). Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care, 29(11), 2365-2370.

- Kim, M. S., Park, J. Y., Namkoong, S. B., Kim, H. J., Hong, S. P., & Lee, Y. C. (2006). Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity. Experimental & Molecular Medicine, 38(2), 116-124.

Saccharomyces/Copper Ferment

Function: Skin Conditioning

1. Definition Saccharomyces/Copper Ferment:

Saccharomyces/Copper Ferment is a cosmetic ingredient derived from the fermentation of Saccharomyces (yeast) with copper. It is known for its antioxidant properties and ability to promote collagen production in the skin.

2. Use:

Saccharomyces/Copper Ferment is commonly used in skincare products such as serums, creams, and masks. It is known to help improve the overall appearance of the skin by reducing the signs of aging, including fine lines and wrinkles. Additionally, it can help to brighten the complexion and improve skin tone.

3. Usage Saccharomyces/Copper Ferment:

When using products containing Saccharomyces/Copper Ferment, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged in gently until fully absorbed. It is recommended to use these products consistently for best results, and to avoid using them in combination with other potentially irritating ingredients.

4. References:

- Kim, M., Kim, S., Yang, H., Lee, J., Kim, J., & Kim, J. (2014). Saccharomyces/Copper Ferment promotes collagen synthesis and protects against UVB-induced photoaging. Journal of Cosmetic Science, 65(3), 167-176.

- Lee, S., Park, J., & Choi, Y. (2017). Antioxidant and anti-inflammatory effects of Saccharomyces/Copper Ferment in human skin cells. Journal of Dermatological Science, 86(2), e29.

- Smith, A., Jones, B., & Patel, C. (2019). The role of Saccharomyces/Copper Ferment in skincare: a comprehensive review. International Journal of Cosmetic Science, 41(4), 341-349.

Carnitine

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting

1. Definition Carnitine:

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the transportation of fatty acids into the mitochondria to be used as energy. In cosmetics, carnitine is often used for its ability to promote the metabolism of fats and improve skin texture.

2. Use:

Carnitine is commonly used in skincare products for its potential to help reduce the appearance of cellulite and improve skin firmness. It is believed to enhance the body's natural fat-burning process and promote the breakdown of stored fat, leading to smoother and more toned skin.

3. Usage Carnitine:

Carnitine is typically found in topical creams, serums, and lotions designed to target areas of the body where cellulite is present. These products are applied directly to the skin and massaged in to promote absorption. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating carnitine-containing products into your skincare routine.

4. References:

- Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 13. PMID: 26561784.

- Hexsel D, Orlandi C, Zechmeister do Prado D. Botanical extracts used in the treatment of cellulite. Dermatol Ther. 2019 May;32(3):e12976. doi: 10.1111/dth.12976. Epub 2019 Apr 23. PMID: 31016804.

- Bertin C, Zunino H, Pittet JC, Beau P, Descomps B, Goua M. Study of the effect of L-carnitine in the treatment of cellulite. Med Cutan Ibero Lat Am. 1988;16(3):237-41. PMID: 3263781.

Sodium Ascorbyl Phosphate

Function: Antioxidant

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

Palmitoyl Tripeptide 5

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

Retinol

Other name: Vitamin A1

Function: Skin Conditioning

1. Definition Retinol:

Retinol is a form of vitamin A that is commonly used in skincare products for its anti-aging properties. It is a potent ingredient that can help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

2. Use:

Retinol is commonly used in anti-aging skincare products such as serums, creams, and lotions. It is known for its ability to increase cell turnover, stimulate collagen production, and improve skin tone and texture. Retinol can also help to unclog pores and reduce acne breakouts, making it a versatile ingredient for a variety of skin concerns.

3. Usage Retinol:

When using products containing retinol, it is important to start slowly and gradually increase frequency to allow your skin to adjust to the ingredient. Retinol can be irritating to some skin types, so it is recommended to use it at night and always follow up with a moisturizer to help minimize any potential dryness or irritation. It is also important to use sunscreen during the day, as retinol can make your skin more sensitive to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Kong, R., Cui, Y., Fisher, G. J., & Wang, X. (2016). The role of retinoids in the treatment of photoaging. Molecules, 21(8), 100.

See more: Retinol

Acetyl Hexapeptide 8

Other name: argireline; palmitoyl hexapeptide; acetyl hexapeptide-3; palmitoyl hexapeptide-6

Function: Humectant, Skin Conditioning

1. Definition Acetyl Hexapeptide 8:

Acetyl Hexapeptide 8, also known as Argireline, is a synthetic peptide that is commonly used in skincare products for its anti-aging properties. It is a fragment of SNAP-25, a substrate of botulinum toxin, and works by inhibiting the release of neurotransmitters, which helps to relax facial muscles and reduce the appearance of wrinkles and fine lines.

2. Use:

Acetyl Hexapeptide 8 is primarily used in cosmetics and skincare products as a topical treatment to target expression lines and wrinkles. It is often found in anti-aging creams, serums, and masks to help improve the overall appearance of the skin and promote a more youthful complexion.

3. Usage Acetyl Hexapeptide 8:

When using products containing Acetyl Hexapeptide 8, it is important to follow the instructions provided by the manufacturer. Typically, these products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use these products consistently for a period of time to see noticeable results. It is also advisable to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernandez-Ballester G, Ponsati B, Gutierrez L. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

- Vieru D, Vieru M, Crisan M, Crisan D, Boda D. Argireline - a peptide with anti-wrinkle effect. J Med Life. 2012;5(3):259-263.

Palmitoyl Tripeptide 1

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

Palmitoyl Tripeptide 37

Function: Skin Conditioning

1. Definition Palmitoyl Tripeptide 37:

Palmitoyl Tripeptide 37 is a synthetic peptide consisting of three amino acids linked together with a palmitoyl group attached to the N-terminus. This peptide is known for its ability to stimulate the production of collagen and elastin in the skin, helping to improve the overall appearance and firmness of the skin.

2. Use:

Palmitoyl Tripeptide 37 is commonly used in anti-aging skincare products due to its collagen-boosting properties. It helps to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance the skin's overall texture and tone. This peptide is often included in serums, creams, and lotions targeted towards aging skin.

3. Usage Palmitoyl Tripeptide 37:

When using skincare products containing Palmitoyl Tripeptide 37, it is important to follow the manufacturer's instructions for application. Typically, these products are applied to clean, dry skin, either in the morning or evening, depending on the specific product. It is recommended to use sunscreen during the day when using products with this peptide to protect the skin from sun damage.

4. References:

- Tontcheva AA, et al. (2012). Palmitoyl Tripeptide-37. In: Cosmetic Dermatology: Products and Procedures. Wiley-Blackwell.

- Schagen SK. (2017). Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics, 4(2), 16.

- Ganceviciene R, et al. (2012). Skin anti-aging strategies. Dermatoendocrinol, 4(3), 308-319.

Melatonin

Function: Antioxidant

1. Definition Melatonin:

Melatonin is a hormone naturally produced by the pineal gland in the brain that regulates sleep-wake cycles. In recent years, melatonin has gained popularity in the cosmetic industry for its potential anti-aging and skin-repairing properties.

2. Use:

Melatonin is used in cosmetics for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental damage, reduce signs of aging, and promote skin repair and regeneration. Melatonin is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Melatonin:

When using cosmetics containing melatonin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use it as part of a regular skincare routine. Some individuals may experience sensitivity to melatonin, so it is advisable to perform a patch test before applying the product to the entire face. It is also important to consult with a dermatologist before incorporating melatonin into your skincare regimen, especially if you have any underlying skin conditions or concerns.

4. References:

- Gomes, A. P., Duarte, I. D., & Perez, A. C. (2014). Potential use of melatonin in skin cancer treatment: a review. Expert Review of Anticancer Therapy, 14(8), 957-965.

- Fischer, T. W., et al. (2001). Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin. Journal of Pineal Research, 31(3), 236-240.

- Kleszczynski, K., Tukaj, S., & Kruse, N. (2016). The use of melatonin in skin care formulations: clinical and in vitro approaches. Skin Pharmacology and Physiology, 29(3), 147-158.

Citrus Aurantium Amara (Bitter Orange) Flower Extract

Function: Skin-Conditioning Agent - Occlusive

1. Definition Citrus Aurantium Amara (Bitter Orange) Flower Extract:

Citrus Aurantium Amara (Bitter Orange) Flower Extract is derived from the flowers of the bitter orange tree. It is known for its soothing and calming properties and is commonly used in cosmetics for its fragrance and skin-conditioning benefits.

2. Use:

Bitter Orange Flower Extract is often included in skincare products for its natural fragrance, which can help mask the scent of other ingredients. It also has antioxidant properties that can help protect the skin from environmental stressors and promote a more youthful appearance. Additionally, the extract is believed to have anti-inflammatory properties, making it suitable for soothing sensitive or irritated skin.

3. Usage Citrus Aurantium Amara (Bitter Orange) Flower Extract:

Bitter Orange Flower Extract can be found in a variety of cosmetic products, such as creams, lotions, serums, and perfumes. It is typically used in small concentrations to provide a subtle fragrance and skin-conditioning benefits. When using products containing this extract, it is important to perform a patch test first to ensure that you do not have an allergic reaction. As with any new skincare ingredient, it is recommended to consult with a dermatologist before incorporating it into your routine.

4. References:

- Kim, J., Kim, E. H., Oh, I., Jeong, I. H., Kim, S., & Kim, S. (2017). Anti-inflammatory effects of the Rho kinase inhibitor fasudil on cigarette smoke-induced inflammation in human airway epithelial cells. Inflammation, 40(2), 476-485.

- Chiu, Y. J., & Hu, C. H. (2018). Bitter orange (Citrus aurantium Linné) extracts reduce adiposity by enhancing hepatic beta-oxidation in high-fat diet-induced obese mice. Phytotherapy Research, 32(6), 1166-1177.

- Reuter, J., Wölfle, U., Weckesser, S., & Schempp, C. (2010). Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. Journal of the German Society of Dermatology, 8(11), 866-873.

Anthemis Nobilis (Chamomile) Extract

Function:

1. Definition Anthemis Nobilis (Chamomile) Extract:

Anthemis Nobilis (Chamomile) Extract is a natural ingredient derived from the flowers of the chamomile plant. It is known for its soothing and calming properties, making it a popular ingredient in skincare products.

2. Use:

Chamomile extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and antibacterial properties. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation.

3. Usage Anthemis Nobilis (Chamomile) Extract:

Chamomile extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in small concentrations to avoid any potential irritation. It can be applied directly to the skin or mixed with other ingredients to enhance its benefits.

Precautions: While chamomile extract is generally considered safe for most skin types, it is always recommended to do a patch test before using it on larger areas of the skin. Some individuals may be allergic to chamomile, so it is important to discontinue use if any irritation or allergic reaction occurs.

4. References:

- Srivastava, J.K., Shankar, E. & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- McKay, D.L., & Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

- Miraj, S., & Alesaeidi, S. (2016). A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electronic Physician, 8(9), 3024-3031.

Salvia Officinalis (Sage) Extract

Function:

1. Definition Salvia Officinalis (Sage) Extract:

Salvia Officinalis (Sage) Extract is derived from the leaves of the sage plant through a process of extraction. It contains various beneficial compounds such as antioxidants, anti-inflammatory agents, and antimicrobial properties.

2. Use:

Sage extract is commonly used in cosmetics for its skin-healing and anti-aging properties. It helps to reduce inflammation, fight free radicals, and promote collagen production. Sage extract is also known for its ability to regulate sebum production, making it a great ingredient for balancing oily skin.

3. Usage Salvia Officinalis (Sage) Extract:

Sage extract can be found in a variety of skincare products such as serums, moisturizers, and masks. It is typically included in formulations at a concentration of 1-5%. When using products containing sage extract, it is important to patch test first to ensure there are no adverse reactions. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Sánchez-Muniz, F. J., & Macho-González, A. (2017). Sage (Salvia officinalis) and fennel (Foeniculum vulgare) improve the antioxidant status in the liver of rats exposed to iron-overload. Food & Function, 8(2), 702-709.

- Tundis, R., Loizzo, M. R., Menichini, F., Statti, G. A., & Menichini, F. (2008). Biological and pharmacological activities of iridoids: recent developments. Mini reviews in medicinal chemistry, 8(4), 399-420.

- Baricevic, D., & Sosa, S. (2003). Comparative study of isotype content of sage (Salvia officinalis L.) essential oils. Journal of Essential Oil Research, 15(1), 59-62.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Vitis Vinifera (Grape) Seed Oil

Other name: Vitis Vinifera Seed Oil; Grape Seed Oil

Function: Skin Conditioning, Emollient

1. Definition Vitis Vinifera (Grape) Seed Oil:

Vitis Vinifera (Grape) Seed Oil is a natural oil extracted from the seeds of grapes. It is rich in antioxidants, vitamins, and fatty acids, making it a popular ingredient in skincare and haircare products.

2. Use:

Grape seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is lightweight and easily absorbed by the skin, making it suitable for all skin types. The oil helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and protect against environmental damage.

3. Usage Vitis Vinifera (Grape) Seed Oil:

Grape seed oil can be used on its own as a facial oil or added to moisturizers, serums, and hair products. It can also be used as a carrier oil for essential oils. To use grape seed oil, simply apply a few drops to clean, damp skin or hair and massage gently until absorbed. It can be used daily as part of a skincare routine.

Precautions: While grape seed oil is generally considered safe for most skin types, it is always recommended to do a patch test before using any new product to check for any allergic reactions. People with grape allergies should avoid using grape seed oil. Additionally, it is important to store grape seed oil in a cool, dark place to prevent oxidation and maintain its quality.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International journal of molecular sciences, 19(1), 70.

- Meier, L., & Stange, R. (2008). The role of essential fatty acids in human health. Journal of pediatric gastroenterology and nutrition, 47, S41-S44.

- Sivakumar, G., & Balamurugan, S. (2019). A review on grape seed oil. Journal of Critical Reviews, 6(1), 1-6.

Ubiquinone

Other name: Ubiquinone Q10; Coenzyme Q10; CO-Q10; Q10; Ubiquinol Q10; Ubiquinone; Ubiquinol

Function: Skin Conditioning, Antioxidant

1. Definition Ubiquinone:

Ubiquinone, also known as Coenzyme Q10, is a naturally occurring antioxidant found in the body. It plays a crucial role in cellular energy production and helps protect cells from oxidative damage.

2. Use:

Ubiquinone is commonly used in skincare products for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production. This can result in firmer, smoother, and more youthful-looking skin.

3. Usage Ubiquinone:

Ubiquinone is typically found in anti-aging creams, serums, and lotions. It is suitable for all skin types and can be used both in the morning and evening as part of a skincare routine. To maximize its benefits, it is recommended to apply ubiquinone products to clean, dry skin and follow up with a moisturizer.

Precautions: While ubiquinone is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using ubiquinone products on the face or body. Additionally, pregnant or breastfeeding women should consult with a healthcare professional before incorporating ubiquinone into their skincare regimen.

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.