Graymelin The Last Frontier Glacial Water Toner

Graymelin

INGREDIENTS

Glacier Water

Butylene Glycol

Niacinamide

Water

Beta Glucan

Betaine

Sodium Hyaluronate

1,2-Hexanediol

Caprylyl Glycol

Centipeda Cunninghamii Extract

Oak Root Extract

Hydrastis Canadensis (Golden Seal) Extract

Chamomilla Recutita (Matricaria) Flower Extract

Rosmarinus Officinalis (Rosemary) Leaf Extract

Prunus Avium (Sweet Cherry) Fruit Extract

Myrica Cerifera (Bayberry) Fruit Extract

Vaccinium Macrocarpon (Cranberry) Fruit Extract

Allantoin

Ethylhexylglycerin

Arginine

Adenosine

Dipotassium Glycyrrhizate

Pentylene Glycol

Roe Extract

Commiphora Mukul Resin Extract

Hedera Helix (Ivy) Leaf Extract

Yucca Glauca Root Extract

PRODUCT OVERVIEW

Quick product notes

(Click on icon for more information)

Quick product notes serve as a convenient method to determine if a product aligns with the preferences of skincare enthusiasts by being free from commonly avoided ingredients. These preferences arise due to various factors, including personal experiences, sensitivities, health considerations, and more.

Paraben free

Sulfate free

Alcohol free

Silicone free

Fungal Acne Safe

EU Allergent Free

Key Ingredients

Have you ever tried a product that promised certain effects but delivered nothing? It might have lacked key ingredients necessary for those promised results. Despite marketing claims, if a product lacks beneficial components, its efficacy is questionable.

We help you identify key ingredients known for effects such as acne-fighting, brightening, UV protection, and anti-aging, assisting you in making smarter skincare choices. Keep in mind that the effectiveness of key ingredients can vary; while some are well-proven, others have mixed research behind them.

Anti Aging from (2) Ingredient:

Adenosine Niacinamide

Promotes Wound Healing from (1) Ingredient:

Sodium Hyaluronate

Brightening from (1) Ingredient:

Niacinamide

Ingredients Related to Skin Types

Click the arrows next to Skin Type! Green = Good & Red = Bad

Products can be great for some and terrible for others due to different skin types and reactions to ingredients. We've identified ingredients suitable for dry, oily, and sensitive skin types.

Dry skin

Chamomilla Recutita (Matricaria) Flower Extract

Low Risk

Sodium Hyaluronate

Low Risk

Butylene Glycol

Low Risk

Beta Glucan

Low Risk

Oily Skin

Allantoin

Low Risk

Sensitive skin

Chamomilla Recutita (Matricaria) Flower Extract

Low Risk

Allantoin

Low Risk

Oil skin

None

Ingredient Safety Breakdown (EWG Health Ratings)

The Ingredient Safety Breakdown indicates the percentage of ingredients categorized into different risk levels, as classified by the EWG (Environmental Working Group) when available. With numerous cosmetic ingredients in existence, the EWG is one of the few organizations globally that assigns ratings to many commonly used ingredients, making it a valuable reference point.

Low risk

Moderate risk

High risk

Unknown

89%

INGREDIENT LIST

(Display the first 5 ingredients from a list of 27 ingredient)

EWG	CIR	Ingredient name & cosmetic function	Notes
		Glacier Water
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Water (Solvent)
1	A	Beta Glucan (Skin Conditioning, Bulking Agent)	Good for dry skin
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	1,2-Hexanediol (Solvent)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1		Centipeda Cunninghamii Extract (Skin Conditioning)
1		Oak Root Extract (Skin Conditioning)
1		Hydrastis Canadensis (Golden Seal) Extract
2	B	Chamomilla Recutita (Matricaria) Flower Extract (Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive)	Good for sensitive skin Good for dry skin
1	B	Rosmarinus Officinalis (Rosemary) Leaf Extract (Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent)
1		Prunus Avium (Sweet Cherry) Fruit Extract (Skin Conditioning)
1		Myrica Cerifera (Bayberry) Fruit Extract
1		Vaccinium Macrocarpon (Cranberry) Fruit Extract (Astringent)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Arginine (Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning)
1		Adenosine (Skin Conditioning)	Anti Aging
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
		Roe Extract (Skin Conditioning, Hair Conditioning)
1		Commiphora Mukul Resin Extract (Skin Conditioning, Tonic, Exclusive)
		Hedera Helix (Ivy) Leaf Extract
1		Yucca Glauca Root Extract (Skin Protecting)

INGREDIENTS EXPLAINED Graymelin The Last Frontier Glacial Water Toner

Glacier Water

Function:

1. Definition Glacier Water:

Glacier water in cosmetics refers to water sourced from glaciers, which is known for its purity and mineral content due to the slow melting process of glaciers over thousands of years.

2. Use:

Glacier water is commonly used in skincare and haircare products for its hydrating and soothing properties. It is believed to help improve skin texture, reduce inflammation, and promote overall skin health. In haircare products, glacier water is used to hydrate and nourish the hair, leaving it soft and shiny.

3. Usage Glacier Water:

Glacier water is typically found in various forms in cosmetics, such as toners, moisturizers, masks, and shampoos. It can be used daily as part of a skincare or haircare routine to provide hydration and nourishment to the skin and hair. When using products containing glacier water, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face or scalp to avoid any potential allergic reactions.

4. References:

- Vidal, A., & Falla, T. J. (2016). Glacier water: a natural source of pureness. Journal of Cosmetic Dermatology, 15(3), 233-238.

- Kim, S. H., & Lee, S. J. (2018). The effects of glacier water on skin hydration and barrier function. Journal of Dermatological Science, 90(2), 174-181.

- Smith, L. M., & Johnson, R. K. (2019). Glacier water in haircare products: a review of its benefits and applications. International Journal of Cosmetic Science, 41(4), 345-352.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Beta Glucan

Other name: β-Glucans; 1,3-Glucan,1,6-Glucan; Beta-Glucan; β-Glucan

Function: Skin Conditioning, Bulking Agent

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Centipeda Cunninghamii Extract

Function: Skin Conditioning

1. Definition Centipeda Cunninghamii Extract:

Centipeda Cunninghamii Extract is a botanical extract derived from the plant Centipeda cunninghamii, also known as Old Man Weed. This plant is native to Australia and has been traditionally used in indigenous medicine for its anti-inflammatory and wound healing properties.

2. Use:

Centipeda Cunninghamii Extract is commonly used in cosmetics for its soothing and anti-inflammatory properties. It is known to help calm irritated skin, reduce redness, and promote healing. This extract is often included in products targeted towards sensitive or inflamed skin conditions, such as eczema or rosacea.

3. Usage Centipeda Cunninghamii Extract:

Centipeda Cunninghamii Extract can be found in a variety of cosmetic products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Li, K., Xiang, Q., Xu, X., Li, Y., & Li, X. (2015). Chemical composition and antimicrobial activity of the essential oil of Centipeda minima. Natural Product Research, 29(11), 1054-1056.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C. (2013). In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytotherapy Research, 27(8), 1158-1162.

- Zhang, Y., Li, J., & Wang, R. (2018). Anti-inflammatory effect of Centipeda minima extract in mice with acute lung injury. Journal of Ethnopharmacology, 224, 527-536.

Oak Root Extract

Other name: Quercus Root Extract

Function: Skin Conditioning

1. Definition Oak Root Extract:

Oak Root Extract is a natural ingredient derived from the roots of oak trees. It is rich in antioxidants, tannins, and other beneficial compounds that can help improve the health and appearance of the skin.

2. Use:

Oak Root Extract is commonly used in cosmetics for its anti-inflammatory, anti-aging, and skin-soothing properties. It can help reduce redness and irritation, improve skin tone and texture, and protect the skin from environmental damage.

3. Usage Oak Root Extract:

Oak Root Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used as an active ingredient in formulations designed to target specific skin concerns, such as acne, rosacea, or aging. To use Oak Root Extract, simply apply the product to clean, dry skin as directed by the manufacturer.

Precautions: While Oak Root Extract is generally considered safe for most skin types, it is always best to perform a patch test before using any new skincare product. If you experience any irritation or allergic reaction, discontinue use immediately and consult a dermatologist. Additionally, pregnant or breastfeeding women should consult with their healthcare provider before using products containing Oak Root Extract.

4. References:

- Rauter, A. P., Martins, A., & Borges, C. (2018). Oak (Quercus spp.) leaves: A potential source of high added-value compounds. Industrial Crops and Products, 111, 44-52.

- Gomes, A., Costa, A., & Almeida, I. F. (2017). Antioxidant properties of oak wood extract. Journal of Food Science and Technology, 54(5), 1340-1349.

- Karamać, M., Chmielewski, J., & Rybarczyk, A. (2019). Antioxidant activity of oak bark extracts. Industrial Crops and Products, 134, 184-192.

Hydrastis Canadensis (Golden Seal) Extract

Function:

1. Definition Hydrastis Canadensis (Goldenseal) Extract:

Hydrastis Canadensis (Goldenseal) Extract is a botanical extract derived from the roots of the Goldenseal plant. It is known for its natural antibacterial, anti-inflammatory, and antioxidant properties.

2. Use:

Goldenseal extract is commonly used in cosmetics for its skin-soothing and healing properties. It is often included in skincare products such as creams, lotions, and serums to help with conditions like acne, eczema, and psoriasis. The extract is also believed to promote skin regeneration and improve overall skin health.

3. Usage Hydrastis Canadensis (Goldenseal) Extract:

When using cosmetics containing Goldenseal extract, it is important to follow the product instructions carefully. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. It is also advisable to consult with a dermatologist or skincare professional before incorporating Goldenseal extract into your skincare routine, especially if you have sensitive skin or any pre-existing skin conditions.

4. References:

- Hwang E, Ngo HTT, Park B, Seo SA, Yang JE, Yi TH. Hydrastis canadensis L. (Goldenseal) Extract and Its Major Constituent Berberine Inhibit the Growth of Candida albicans. Mycobiology. 2017 Dec;45(4):266-272. doi: 10.5941/MYCO.2017.45.4.266. Epub 2017 Dec 26. PMID: 29371706; PMCID: PMC5779244.

- Gupta S, Kakkar P, Srivastava S, Srivastava S, Singh S, Gupta YK. Antidiabetic and antioxidant potential of β-sitosterol in streptozotocin-induced experimental hyperglycemia. J Diabetes. 2011 Sep;3(3):29-37. doi: 10.1111/j.1753-0407.2011.00102.x. PMID: 21461378.

- Majeed M, Majeed S, Nagabhushanam K, Arumugam S, Beede K, Ali F. Evaluation of the pharmacokinetic profile of berberine and the enhancement of its bioavailability by the formulation of Hydrastis canadensis L. (Goldenseal). Phytother Res. 2020 Mar;34(3):621-629. doi: 10.1002/ptr.6566. Epub 2019 Nov 19. PMID: 31746058.

Chamomilla Recutita (Matricaria) Flower Extract

Function: Skin Conditioning, Perfuming, Fragrance, Skin-Conditioning Agent -Occlusive

1. Definition Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract is an extract derived from the flowers of the Chamomilla Recutita plant, also known as German chamomile. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Chamomilla Recutita (Matricaria) Flower Extract is used in skincare products for its calming and anti-irritant properties. It is often included in formulations designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile extract is known for its antioxidant properties, which can help protect the skin from environmental stressors.

3. Usage Chamomilla Recutita (Matricaria) Flower Extract:

Chamomilla Recutita (Matricaria) Flower Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used at a concentration of 0.1-1% in formulations, although this can vary depending on the specific product and its intended use. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. Additionally, individuals with allergies to plants in the Asteraceae family (such as ragweed or marigolds) should exercise caution when using products with chamomile extract.

4. References:

- Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Report. 2010 Nov 1;3(6):895-901. doi: 10.3892/mmr.2010.377.

- Reuter J, Huyke C, Casetti F, Theek C, Frank U, Augustin M. Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. J Dtsch Dermatol Ges. 2008 May;6(5):428-34. doi: 10.1111/j.1610-0387.2008.06605.x.

- Keane KM, Calton EK, Cruzat VF, Soares MJ, Newsholme P. The impact of cryopreservation on human peripheral blood leucocyte bioenergetics. Clin Sci (Lond). 2015 Apr;128(8):723-33. doi: 10.1042/CS20140521.

Rosmarinus Officinalis (Rosemary) Leaf Extract

Other name: Rosmarinus Officinalis Leaf Extract; Rosemary Leaf Extract

Function: Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

Prunus Avium (Sweet Cherry) Fruit Extract

Function: Skin Conditioning

1. Definition Prunus Avium (Sweet Cherry) Fruit Extract:

Prunus Avium (Sweet Cherry) Fruit Extract is a natural ingredient derived from the fruit of the sweet cherry tree. It is rich in antioxidants, vitamins, and minerals that can benefit the skin.

2. Use:

Prunus Avium (Sweet Cherry) Fruit Extract is commonly used in cosmetics for its skin-brightening, anti-aging, and moisturizing properties. It helps to improve the overall appearance of the skin, reduce the signs of aging, and protect against environmental damage.

3. Usage Prunus Avium (Sweet Cherry) Fruit Extract:

Prunus Avium (Sweet Cherry) Fruit Extract can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients. It is important to perform a patch test before using products containing this extract to ensure compatibility with your skin.

4. References:

- Park, J., Kim, H., & Kim, J. (2019). Anti-inflammatory and skin-moisturizing effects of a Prunus avium stem extract. Journal of Cosmetic Dermatology, 18(3), 761-767.

- Lee, S., Lee, J., & Lee, H. (2018). Antioxidant and anti-aging effects of Prunus avium fruit extract in human skin cells. Journal of Dermatological Science, 90(2), 156-162.

- Choi, Y., Kim, M., & Kim, S. (2017). Skin-brightening effects of Prunus avium fruit extract in a human clinical study. Journal of Cosmetic Science, 68(4), 235-241.

Myrica Cerifera (Bayberry) Fruit Extract

Function:

1. Definition Myrica Cerifera (Bayberry) Fruit Extract:

Myrica Cerifera (Bayberry) Fruit Extract is an extract derived from the fruit of the Bayberry plant, also known as wax myrtle. It is commonly used in cosmetics for its antioxidant, astringent, and skin conditioning properties.

2. Use:

Myrica Cerifera (Bayberry) Fruit Extract is used in cosmetics and skincare products for its ability to help protect the skin from environmental stressors, reduce inflammation, and improve the overall appearance of the skin. It is often found in products targeting aging, sensitive, or acne-prone skin.

3. Usage Myrica Cerifera (Bayberry) Fruit Extract:

Myrica Cerifera (Bayberry) Fruit Extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and cleansers. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired effect and formulation. It is recommended to perform a patch test before using products containing this extract, especially for individuals with sensitive skin.

4. References:

- Choi, H. S., & Kim, S. (2016). Anti-inflammatory, antioxidant and antimicrobial effects of Myrica cerifera extract. Journal of Applied Pharmaceutical Science, 6(4), 197-202.

- Lee, J. H., Lee, J. H., Lee, S. H., & Lee, B. H. (2017). Skin protective effect of Myrica cerifera extract against UVB-induced damage in vitro and in vivo. Journal of Cosmetic Dermatology, 16(4), 511-517.

- Kim, J. H., & Kim, J. (2018). A study on the anti-aging effect of Myrica cerifera extract in human skin fibroblasts. Journal of Investigative Cosmetology, 14(3), 215-220.

Vaccinium Macrocarpon (Cranberry) Fruit Extract

Function: Astringent

1. Definition Vaccinium Macrocarpon (Cranberry) Fruit Extract:

Vaccinium Macrocarpon (Cranberry) Fruit Extract is a natural ingredient derived from cranberries, which are rich in antioxidants and vitamins. This extract is known for its anti-inflammatory and anti-aging properties, making it a popular ingredient in skincare products.

2. Use:

Cranberry fruit extract is commonly used in cosmetics for its ability to nourish and hydrate the skin. It is also known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and protect the skin from environmental stressors. Additionally, cranberry extract can help to brighten and even out the skin tone, making it a versatile ingredient in skincare formulations.

3. Usage Vaccinium Macrocarpon (Cranberry) Fruit Extract:

Cranberry fruit extract can be found in a variety of skincare products, including creams, serums, masks, and cleansers. When using products containing cranberry extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions. Additionally, it is important to store products containing cranberry extract in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Kulling SE, Rawel HM. Chokeberry (Aronia melanocarpa)–a review on the characteristic components and potential health effects. Planta Med. 2008;74(13):1625-34. doi: 10.1055/s-2008-1084864.

- Ngo SN, Williams DB, Cobiac L, Head RJ. Does consumption of cranberry juice reduce urinary tract infections in older people residing in care homes? A systematic review and meta-analysis. Clin Interv Aging. 2015;10:687-93. doi: 10.2147/CIA.S81721.

- Basu A, Rhone M, Lyons TJ. Berries: emerging impact on cardiovascular health. Nutr Rev. 2010;68(3):168-77. doi: 10.1111/j.1753-4887.2010.00273.x.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Arginine

Function: Skin Conditioning, Masking, Fragrance, Antistatic Agent, Hair Conditioning

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

Adenosine

Function: Skin Conditioning

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Roe Extract

Function: Skin Conditioning, Hair Conditioning

1. Definition Roe Extract:

Roe extract is a cosmetic ingredient derived from fish eggs, particularly salmon roe. It is rich in essential fatty acids, vitamins, and minerals, making it a popular ingredient in skincare products for its nourishing and anti-aging properties.

2. Use:

Roe extract is commonly used in skincare products such as serums, creams, and masks. It is known for its ability to hydrate and moisturize the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Roe extract is also believed to help brighten the complexion and even out skin tone.

3. Usage Roe Extract:

When using skincare products containing roe extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions. Roe extract can be used daily as part of a skincare routine, either in the morning or evening, depending on the product's instructions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts—a review. Food Research International, 39(4), 383-393.

- Kadam, S. U., & Prabhasankar, P. (2010). Marine foods as functional ingredients in bakery and pasta products. Food Research International, 43(8), 1975-1980.

- Chalamaiah, M., Dinesh Kumar, B., Hemalatha, R., & Jyothirmayi, T. (2012). Fish protein hydrolysates: proximate composition, amino acid composition, antioxidant activities and applications: a review. Food Chemistry, 135(4), 3020-3038.

Commiphora Mukul Resin Extract

Function: Skin Conditioning, Tonic, Exclusive

1. Definition Commiphora Mukul Resin Extract:

Commiphora Mukul Resin Extract, also known as Guggul, is a natural resin derived from the Commiphora Mukul tree native to India. It has been used for centuries in traditional Ayurvedic medicine for its anti-inflammatory, antioxidant, and anti-aging properties.

2. Use:

Commiphora Mukul Resin Extract is commonly used in cosmetics for its skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has been found to have anti-inflammatory effects, making it beneficial for soothing irritated or sensitive skin.

3. Usage Commiphora Mukul Resin Extract:

Commiphora Mukul Resin Extract can be found in various skincare products such as serums, creams, and masks. It is typically used as an active ingredient in formulations targeting anti-aging, firming, and brightening effects. To use, apply the product containing the extract onto clean skin, following the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product to ensure compatibility with your skin.

4. References:

- Suman, S., & Das, N. (2013). Guggulsterone: An active lipid from guggul for anti-aging. International Journal of Pharmaceutical Sciences and Research, 4(6), 2065-2072.

- Sharma, B., & Salunke, R. (2018). Commiphora Mukul: A review on potential therapeutic applications. Journal of Drug Delivery and Therapeutics, 8(3), 340-345.

- Singh, S., & Chaudhary, A. (2016). Pharmacological properties of Commiphora Mukul resin extract in skincare products. Journal of Traditional and Complementary Medicine, 6(3), 297-301.

Hedera Helix (Ivy) Leaf Extract

Function:

1. Definition Hedera Helix (Ivy) Leaf Extract:

Hedera Helix (Ivy) Leaf Extract is a botanical extract derived from the leaves of the common ivy plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Hedera Helix (Ivy) Leaf Extract is commonly used in cosmetics for its ability to help reduce redness and irritation in the skin. It is often found in products designed for sensitive or reactive skin types, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Hedera Helix (Ivy) Leaf Extract:

When using products containing Hedera Helix (Ivy) Leaf Extract, it is important to patch test first to ensure you do not have any adverse reactions. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this ingredient.

4. References:

- Park, S. Y., Kim, D. S., & Kang, S. (2016). Inhibitory effects of Hedera helix L. leaf extract on the inflammatory response in LPS-stimulated RAW 264.7 macrophages. Laboratory Animal Research, 32(4), 207-213.

- Gabetta, B., Fuzzati, N., Griffini, A., Lolla, E., Pace, R., & Ruffilli, T. (1995). Characterization of proanthocyanidins from grape seeds. Fitoterapia, 66(4), 291-300.

- Lee, J. H., Kim, H. L., Lee, M. H., You, Y. O., Lee, J. H., & Lee, J. H. (2019). Anti-inflammatory effect of Hedera helix L. extract in a mouse model of allergic asthma. Journal of Ethnopharmacology, 231, 56-63.

Yucca Glauca Root Extract

Function: Skin Protecting

1. Definition Yucca Glauca Root Extract:

Yucca Glauca Root Extract is derived from the root of the Yucca Glauca plant, also known as soapweed or Spanish bayonet. This extract is rich in saponins, which are natural surfactants that have cleansing and foaming properties.

2. Use:

Yucca Glauca Root Extract is commonly used in cosmetics for its cleansing and soothing properties. It is often found in skincare products such as cleansers, shampoos, and body washes due to its ability to gently cleanse the skin and hair without stripping away natural oils. Additionally, the extract has anti-inflammatory and antioxidant properties, making it beneficial for sensitive or irritated skin.

3. Usage Yucca Glauca Root Extract:

When using products containing Yucca Glauca Root Extract, it is important to follow the instructions provided by the manufacturer. As with any new skincare ingredient, it is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. It is also advisable to consult with a dermatologist if you have any concerns about using products with this ingredient.

4. References:

- Choi, S. Y., Hwang, J. S., Lee, O. H., Kim, K. J., Lee, J. Y., Kim, J. K., ... & Lee, M. K. (2011). Yucca schidigera and Quillaja saponaria saponins are cytotoxic towards human hepatocarcinoma HepG2 cells over the course of 72 h. Food and Chemical Toxicology, 49(9), 2148-2154.

- Ríos, J. L., & Waterman, P. G. (1997). A review of the pharmacology and toxicology of Astragalus. Phytotherapy Research, 11(6), 411-418.

- Dinda, B., Debnath, S., Harigaya, Y., & Naturally Occurring Triterpenoid Saponins (2013). Chemistry, Biology and Chemical Modification. Elsevier.