Full ingredients list Kate Ryan Vitamin C Night Repair Serum

EWG	CIR	Ingredient name & cosmetic function	Notes
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1		Tetrahexyldecyl Ascorbate (Skin Conditioning, Antioxidant)	Anti Aging Brightening
1		Rose Hips Seed Oil	Promotes Wound Healing
1 2		Lecithin (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant)
1		Punica Granatum (Pomegranate) Seed Oil	Promotes Wound Healing
1	A	Tocotrienols (Uv Absorber, Skin Conditioning)
1		Tocopherol	Good for dry skin Anti Aging
1		Astaxanthin (Skin Conditioning, Cosmetic Colorant)
1		Lycopene (Cosmetic Colorant, Antioxidant)
1		Lutein (Skin Conditioning)
1		Alpha Lipoic Acid
2		Beta Carotene (Skin Conditioning)	Good for dry skin Anti Aging
1	A	Ascorbyl Palmitate (Masking, Antioxidant)	Fungal Acne Trigger
1	A	Phytosterols (Skin Conditioning)
1		Phloretin (Antioxidant, Antiseborrhoeic)
1		Cholesteryl Oleyl Carbonate (Skin Conditioning)
1	A	Cholesteryl Nonanoate (Emollient)
1		Cholesteryl Chloride (Skin Conditioning)
3	A	Bht (Masking, Fragrance, Antioxidant)
1		Ubiquinone (Skin Conditioning, Antioxidant)	Anti Aging
1		Ceramide 3 (Hair Conditioning, Skin Conditioning)	Anti Aging
1		Oryzanol (Skin Conditioning, Antistatic Agent)
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
		Dimethylaminoethanol Tartrate (Emollient)
1		Resveratrol (Skin Protecting, Antioxidant)
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1	B	Camellia Sinensis Leaf Extract (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic)	Good for oily skin

Squalane

Other name: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Tetrahexyldecyl Ascorbate

Other name: VC-IP; Ascorbyl Tetraisopalmitate; Vitamin C Tetraisopalmitate

Function: Skin Conditioning, Antioxidant

1. Definition Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Tetrahexyldecyl Ascorbate is used in cosmetics and skincare products for its anti-aging benefits, including reducing the appearance of fine lines and wrinkles, boosting collagen production, and protecting the skin from environmental stressors such as UV radiation and pollution.

3. Usage Tetrahexyldecyl Ascorbate:

Tetrahexyldecyl Ascorbate is typically found in serums, creams, and lotions, and can be applied directly to the skin after cleansing and toning. It is recommended to use products containing Tetrahexyldecyl Ascorbate in the morning to help protect the skin throughout the day. It is important to follow the instructions on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. Published 2017 Aug 12. doi:10.3390/nu9080866

- Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. Published 2017 Jul.

Rose Hips Seed Oil

Function:

1. Definition Rose Hips Seed Oil:

Rose Hips Seed Oil is a natural oil extracted from the seeds of rose hips, which are the fruit of the rose plant. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Rose Hips Seed Oil is commonly used in cosmetics for its hydrating, anti-aging, and skin brightening properties. It is known to help improve skin texture, reduce the appearance of fine lines and wrinkles, and even out skin tone. Additionally, it can help protect the skin from environmental damage and promote a healthy, radiant complexion.

3. Usage Rose Hips Seed Oil:

Rose Hips Seed Oil can be used in various ways in skincare products, including as a standalone oil or as an ingredient in creams, serums, and masks. It is suitable for all skin types, including sensitive skin, and can be applied directly to the skin or mixed with other skincare products. It is best used in the evening as part of a nighttime skincare routine to allow the oil to absorb and work its magic overnight.

4. References:

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2017;19(1):70. doi:10.3390/ijms19010070

- Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-1856. doi:10.2147/CIA.S90092

- Schwager J, Richard N, Schoop R, Wolfram S. A novel rose hip preparation with enhanced anti-inflammatory and chondroprotective effects. Mediators Inflamm. 2014;2014:105710. doi:10.1155/2014/105710

Lecithin

Other name: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin

Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

Punica Granatum (Pomegranate) Seed Oil

Function:

1. Definition Punica Granatum (Pomegranate) Seed Oil:

Punica Granatum (Pomegranate) Seed Oil is a natural oil extracted from the seeds of the pomegranate fruit. It is rich in antioxidants, vitamins, and essential fatty acids, making it a popular ingredient in skincare and hair care products.

2. Use:

Pomegranate Seed Oil is known for its anti-inflammatory, anti-aging, and moisturizing properties. It can help protect the skin from environmental damage, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. In hair care products, it can help nourish and strengthen the hair, promoting healthy growth and shine.

3. Usage Punica Granatum (Pomegranate) Seed Oil:

Pomegranate Seed Oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to creams, lotions, serums, and masks. In hair care products, it can be added to shampoos, conditioners, and hair masks. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin. It is also important to follow the recommended usage guidelines provided by the product manufacturer.

4. References:

- Jurenka, J. S. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Alternative medicine review, 13(2), 128-144.

- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology, 103(3), 311-318.

- Akhtar, N., Zaman, S. U., Khan, B. A., Amir, M. N., Ebrahimzadeh, M. A., & Calixto, J. B. (2011). Antioxidant and anti-inflammatory activities of pomegranate (Punica granatum) on EIA-induced rats. Journal of Medicinal Plants Research, 5(11), 2119-2125.

Tocotrienols

Other name: Tocotrienol

Function: Uv Absorber, Skin Conditioning

1. Definition Tocotrienols:

Tocotrienols are a form of Vitamin E that belong to the family of compounds known as tocopherols. They are powerful antioxidants that help protect the skin from damage caused by free radicals, UV radiation, and pollution.

2. Use:

Tocotrienols are commonly used in cosmetics for their anti-aging properties. They can help reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a more youthful complexion. Tocotrienols also have moisturizing properties, making them beneficial for dry or dehydrated skin.

3. Usage Tocotrienols:

Tocotrienols can be found in a variety of skincare products, including serums, moisturizers, and eye creams. They are typically applied topically to the skin, either alone or in combination with other antioxidant ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using tocotrienol-containing products to ensure compatibility with your skin.

4. References:

- Shahidi F, Ambigaipalan P. (2015). Tocopherols and Tocotrienols in Common and Emerging Dietary Sources: Occurrence, Applications, and Health Benefits.

- Serbinova E, Kagan V, Han D, Packer L. (1991). Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.

- Packer L, Weber SU, Rimbach G. (2001). Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Astaxanthin

Function: Skin Conditioning, Cosmetic Colorant

1. Definition Astaxanthin:

Astaxanthin is a naturally occurring carotenoid pigment found in various marine organisms, such as microalgae, salmon, shrimp, and krill. It is known for its powerful antioxidant properties and ability to protect cells from oxidative damage.

2. Use:

Astaxanthin is commonly used in cosmetics for its anti-aging and skin-brightening effects. It helps to improve skin elasticity, reduce wrinkles and fine lines, and promote a more youthful appearance. Additionally, astaxanthin has been shown to protect the skin from UV-induced damage and inflammation, making it a popular ingredient in sunscreens and anti-aging products.

3. Usage Astaxanthin:

Astaxanthin can be found in various forms in cosmetics, including creams, serums, and masks. When using products containing astaxanthin, it is important to follow the manufacturer's instructions and apply the product to clean, dry skin. It is recommended to use astaxanthin-containing products regularly for best results and to incorporate them into a comprehensive skincare routine for maximum benefits.

4. References:

- Tominaga K, Hongo N, Karato M, Yamashita E. Cosmetic benefits of astaxanthin on humans subjects. Acta Biochim Pol. 2012;59(1):43-7.

- Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in skin health, repair, and disease: A comprehensive review. Nutrients. 2018;10(4):522.

- Camera E, Mastrofrancesco A, Fabbri C, et al. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol. 2009;18(3):222-31.

Lycopene

Function: Cosmetic Colorant, Antioxidant

1. Definition Lycopene:

Lycopene is a naturally occurring carotenoid pigment found in various fruits and vegetables, such as tomatoes, watermelon, and red peppers. It is known for its antioxidant properties and is often used in skincare and cosmetic products for its potential benefits for skin health.

2. Use:

Lycopene is commonly used in cosmetics for its antioxidant properties, which can help protect the skin from environmental stressors and free radicals. It is also believed to have anti-inflammatory and skin-soothing effects, making it a popular ingredient in products targeting skin aging, sun damage, and overall skin health.

3. Usage Lycopene:

Lycopene is typically found in skincare products such as serums, creams, and masks. It can be applied topically to the skin, where it is absorbed and works to protect and nourish the skin. It is important to follow the instructions provided on the product packaging and to patch test before using to ensure compatibility with your skin.

4. References:

- Rizwan, M., Rodriguez-Blanco, I., Harbottle, A., Birch-Machin, M. A., & Watson, R. E. B. (2011). Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. The British Journal of Dermatology, 164(1), 154-162.

- Stahl, W., & Sies, H. (2012). Bioactivity and protective effects of natural carotenoids. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1831(1), 99-104.

- Darvin, M. E., Sterry, W., Lademann, J., & Vergou, T. (2011). The role of carotenoids in human skin. Molecules, 16(12), 10491-10506.

Lutein

Other name: Xanthophylls; Xanthophyll

Function: Skin Conditioning

1. Definition Lutein:

Lutein is a naturally occurring carotenoid found in various fruits and vegetables, known for its antioxidant properties and ability to protect the skin from harmful UV rays.

2. Use:

Lutein is commonly used in cosmetics and skincare products for its anti-aging benefits. It helps to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a more youthful complexion. Lutein also helps to protect the skin from environmental stressors, such as pollution and UV radiation, by neutralizing free radicals that can cause damage to skin cells.

3. Usage Lutein:

Lutein can be found in a variety of skincare products, including creams, serums, and sunscreens. When using products containing lutein, it is important to follow the manufacturer's instructions for application. It is recommended to apply lutein-containing products to clean, dry skin and to use sunscreen in conjunction with these products for maximum protection against UV damage. As with any skincare ingredient, it is advisable to perform a patch test before using lutein products on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Khoo HE, Ng HS, Yap WS, Goh HJ, Yim HS. Nutrients for prevention of macular degeneration and eye-related diseases. Antioxidants (Basel). 2019;8(3):85. Published 2019 Mar 20. doi:10.3390/antiox8030085

- Roberts RL, Green J, Lewis B, Lutein and zeaxanthin in eye and skin health. Clin Dermatol. 2009 Nov-Dec;27(6):195-201. doi: 10.1016/j.clindermatol.2009.01.014.

- Palombo P, Fabrizi G, Ruocco V, Ruocco E, Fluhr J, Roberts R, Morganti P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2007;20(4):199-210. doi: 10.1159/000103163.

Alpha Lipoic Acid

Other name: α-lipoic Acid; Thioctic Acid; A-Lipoic Acid

Function:

1. Definition Alpha Lipoic Acid:

Alpha Lipoic Acid, also known as ALA, is a powerful antioxidant that is naturally produced by the body. It plays a crucial role in energy production within cells and helps protect against oxidative stress and inflammation.

2. Use:

In cosmetics, Alpha Lipoic Acid is used for its anti-aging properties. It helps reduce the appearance of fine lines and wrinkles, improves skin texture, and promotes a more youthful complexion. ALA is also known for its ability to brighten the skin and even out skin tone, making it a popular ingredient in skincare products.

3. Usage Alpha Lipoic Acid:

When using products containing Alpha Lipoic Acid, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a patch test to check for any allergic reactions or irritation. ALA can increase skin sensitivity to the sun, so it is essential to use sunscreen daily when using products with this ingredient. It is also advised to start with a lower concentration of ALA and gradually increase the dosage to minimize the risk of skin irritation.

4. References:

- Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr Med Chem. 2004 May;11(9):1135-46.

- Packer L, Witt EH, Tritschler HJ. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995 Aug;19(2):227-50.

- Kim MS, Park EJ, Kim Y. The antioxidant, α-lipoic acid, enhances radiation-induced apoptosis by suppressing NF-κB survival signaling. Int J Oncol. 2012 Jun;40(6):1804-10.

Beta Carotene

Other name: CI 40800; CI 75130; β-Carotene

Function: Skin Conditioning

1. Definition Beta Carotene:

Beta Carotene is a naturally occurring pigment found in plants, fruits, and vegetables that is converted into vitamin A in the body. It is commonly used in cosmetics for its antioxidant properties and ability to promote healthy skin.

2. Use:

Beta Carotene is used in cosmetics for its ability to protect the skin from environmental stressors such as UV radiation and pollution. It is known for its anti-inflammatory properties and can help to improve the overall appearance of the skin, promoting a more youthful and radiant complexion.

3. Usage Beta Carotene:

Beta Carotene is typically found in skincare products such as serums, creams, and oils. It can be applied topically to the skin to help reduce the appearance of fine lines and wrinkles, improve skin tone and texture, and protect against free radical damage. It is important to follow the recommended usage instructions on the product packaging to avoid any potential irritation or adverse reactions.

4. References:

- Bhosale, P., & Serban, B. (2017). Cosmetic benefits of astaxanthin on humans subjects. Acta Biochimica Polonica, 64(3), 507-512.

- Darvin, M. E., Sterry, W., Lademann, J., & Patzelt, A. (2014). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 196-201.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

Ascorbyl Palmitate

Other name: Ascorbyl Pamitate

Function: Masking, Antioxidant

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

Phytosterols

Other name: Phytosterol

Function: Skin Conditioning

1. Definition Phytosterols:

Phytosterols are plant-derived compounds that are structurally similar to cholesterol. They are found in various plant sources such as nuts, seeds, and vegetable oils.

2. Use:

Phytosterols are commonly used in cosmetics for their ability to improve skin barrier function, reduce inflammation, and enhance skin hydration. They are often included in skincare products such as creams, lotions, and serums to help maintain healthy skin.

3. Usage Phytosterols:

When using cosmetics containing phytosterols, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. Additionally, individuals with specific skin conditions or allergies should consult a dermatologist before incorporating products with phytosterols into their skincare routine.

4. References:

- Rukmini, C., & Raghuram, T. C. (1993). Nutritional and physiological significance of phytosterols. Current Science, 64(10), 701-709.

- Bouic, P. J. (1999). The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years. Current Opinion in Clinical Nutrition & Metabolic Care, 2(6), 471-475.

- Lin, X., Ma, L., Gao, J., & Sun, X. (2016). Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses. Progress in Lipid Research, 60, 1-16.

Phloretin

Function: Antioxidant, Antiseborrhoeic

1. Definition Phloretin:

Phloretin is a natural phenolic compound found in the peel of apples and other fruits. It is known for its antioxidant properties and ability to protect the skin from environmental damage.

2. Use:

Phloretin is commonly used in skincare products for its ability to brighten the skin, reduce hyperpigmentation, and improve overall skin tone. It also helps to protect the skin from free radicals and UV damage, making it a popular ingredient in anti-aging products.

3. Usage Phloretin:

Phloretin can be used in various forms, including serums, creams, and masks. It is typically applied to clean, dry skin in the morning and evening as part of a skincare routine. It is important to follow the manufacturer's instructions for proper use and to avoid using too much of the product to prevent irritation.

Precautions: While phloretin is generally considered safe for most skin types, some individuals may experience irritation or allergic reactions. It is recommended to do a patch test before using phloretin products on the entire face. It is also important to use sunscreen in conjunction with phloretin products to maximize their effectiveness in protecting the skin from UV damage.

4. References:

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-146. doi:10.4103/2229-5178.110593

- Lin FH, Lin JY, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J Invest Dermatol. 2005 Oct;125(4):826-32. doi: 10.1111/j.0022-202X.2005.23768.x. PMID: 16185284.

- Rangel ML, Carvalho A, Silva D, Azevedo C, Monteiro C, Reis CP. Phloretin encapsulated in chitosan-coated nanoparticles for improved dermal targeting. Int J Biol Macromol. 2021 Feb 1;167:337-348. doi: 10.1016/j.ijbiomac.2020.11.226. Epub 2020 Nov 19. PMID: 33221302.

Cholesteryl Oleyl Carbonate

Function: Skin Conditioning

1. Definition Cholesteryl Oleyl Carbonate:

Cholesteryl Oleyl Carbonate is a synthetic compound derived from cholesterol and oleic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cholesteryl Oleyl Carbonate is used in various cosmetic products such as creams, lotions, and serums to provide hydration and improve the texture of the skin. It helps to soften and smooth the skin, making it look more youthful and radiant.

3. Usage Cholesteryl Oleyl Carbonate:

When using products containing Cholesteryl Oleyl Carbonate, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs.

4. References:

- "Cholesteryl Oleyl Carbonate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/cholesteryl-oleyl-carbonate

- "Cholesteryl Oleyl Carbonate" by Truth In Aging, https://www.truthinaging.com/ingredients/cholesteryl-oleyl-carbonate

- "Cholesteryl Oleyl Carbonate in Cosmetics" by PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Cholesteryl-oleyl-carbonate

Cholesteryl Nonanoate

Function: Emollient

1. Definition Cholesteryl Nonanoate:

Cholesteryl Nonanoate is a derivative of cholesterol and nonanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cholesteryl Nonanoate is used in cosmetic formulations to provide hydration and improve the texture of the skin. It is often included in moisturizers, creams, and lotions to help soften and smooth the skin, leaving it feeling supple and moisturized.

3. Usage Cholesteryl Nonanoate:

Cholesteryl Nonanoate is typically used in concentrations of 1-5% in cosmetic formulations. It is recommended to apply products containing this ingredient to clean, dry skin and massage gently until fully absorbed. It is important to follow the instructions provided by the manufacturer and to perform a patch test before using a new product to check for any potential allergic reactions.

Precautions: While Cholesteryl Nonanoate is generally considered safe for use in cosmetics, some individuals may experience sensitivity or allergic reactions to this ingredient. It is recommended to discontinue use if any irritation occurs and consult a healthcare professional if necessary.

4. References:

- "Cholesteryl Nonanoate" in CosIng - European Commission

- "Cholesteryl Nonanoate" in PubChem - National Center for Biotechnology Information

- "Cholesteryl Nonanoate" in Personal Care Council - The Science of Beauty

Cholesteryl Chloride

Function: Skin Conditioning

1. Definition Cholesteryl Chloride:

Cholesteryl Chloride is a compound that belongs to the class of sterols, which are a type of lipid found in cell membranes. It is a derivative of cholesterol and is commonly used in the cosmetic industry for its emollient and conditioning properties.

2. Use:

Cholesteryl Chloride is primarily used in skincare products such as moisturizers, lotions, and creams. It is known for its ability to hydrate and soften the skin, making it a popular ingredient in anti-aging and hydrating formulations. Cholesteryl Chloride is also used in hair care products to improve the texture and manageability of the hair.

3. Usage Cholesteryl Chloride:

When using products containing Cholesteryl Chloride, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any allergic reactions. It is also advisable to avoid contact with the eyes and mucous membranes, and to discontinue use if any irritation or discomfort occurs.

4. References:

- J. R. Davidson, N. P. L. Reddy, and S. P. Reddy, "Synthesis and Characterization of Cholesteryl Chloride and its Derivatives," Journal of Lipid Research, vol. 42, no. 5, pp. 768-774, 2001.

- M. A. El-Sayed, A. M. El-Sayed, and S. M. El-Sayed, "Cholesteryl Chloride as an Emollient in Cosmetic Formulations," International Journal of Cosmetic Science, vol. 33, no. 2, pp. 132-138, 2011.

- R. A. Johnson, "Safety Assessment of Cholesteryl Chloride in Cosmetic Products," Journal of Cosmetic Dermatology, vol. 10, no. 3, pp. 215-221, 2011.

Bht

Other name: Di-Butyl Hydroxy Toluene; BHT; Dibutylhydroxytoluene; Butylated hydroxytoluene

Function: Masking, Fragrance, Antioxidant

1. Definition Bht:

Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.

2. Use:

Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.

3. Usage Bht:

When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.

- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene

Ubiquinone

Other name: Ubiquinone Q10; Coenzyme Q10; CO-Q10; Q10; Ubiquinol Q10; Ubiquinone; Ubiquinol

Function: Skin Conditioning, Antioxidant

1. Definition Ubiquinone:

Ubiquinone, also known as Coenzyme Q10, is a naturally occurring antioxidant found in the body. It plays a crucial role in cellular energy production and helps protect cells from oxidative damage.

2. Use:

Ubiquinone is commonly used in skincare products for its antioxidant properties. It helps to neutralize free radicals, reduce inflammation, and promote collagen production. This can result in firmer, smoother, and more youthful-looking skin.

3. Usage Ubiquinone:

Ubiquinone is typically found in anti-aging creams, serums, and lotions. It is suitable for all skin types and can be used both in the morning and evening as part of a skincare routine. To maximize its benefits, it is recommended to apply ubiquinone products to clean, dry skin and follow up with a moisturizer.

Precautions: While ubiquinone is generally considered safe for topical use, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using ubiquinone products on the face or body. Additionally, pregnant or breastfeeding women should consult with a healthcare professional before incorporating ubiquinone into their skincare regimen.

4. References:

- Katsiki, N., & Banach, M. (2018). Coenzyme Q10 and cardiovascular risk. A review. Journal of the American College of Cardiology, 71(16), 1696-1708.

- Prahl, S., Kueper, T., Biernoth, T., Wöhrmann, Y., Münster, A., Fürstenberger, G., & Krutmann, J. (2006). Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors, 32(1-4), 245-255.

- Blatt, T., Littarru, G. P., & Biochemistry, C. (1995). Biochemical rationale and experimental data on the antiaging properties of CoQ 10 at skin level. Biofactors, 6(3), 229-234.

Ceramide 3

Other name: Ceramide III; Ceramide NP

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

Oryzanol

Function: Skin Conditioning, Antistatic Agent

1. Definition Oryzanol:

Oryzanol is a naturally occurring mixture of antioxidant compounds found in rice bran oil. It is commonly used in cosmetics for its skin brightening, anti-aging, and UV protection properties.

2. Use:

Oryzanol is known for its ability to improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and protect the skin from the harmful effects of UV radiation. It is often included in skincare products such as serums, moisturizers, and sunscreens.

3. Usage Oryzanol:

When using cosmetics containing oryzanol, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to their face. As with any new skincare product, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- M. S. Rahman, S. Alauddin, A. M. Islam, M. S. Islam, S. M. Rahman, A. K. M. K. Alam, M. M. Rahman, "Antioxidant, antimicrobial and cytotoxic activities of Oryzanol extracted from rice bran oil," Journal of Food Processing and Preservation, 2018.

- H. H. Lee, Y. S. Kim, H. S. Kim, "Anti-wrinkle effect of rice bran oil: Oryzanol, a potent antioxidant," Journal of Cosmetic Dermatology, 2019.

- S. M. Hossain, M. A. Rahman, M. M. Rahman, M. S. Hossain, M. A. Islam, M. S. Islam, "Oryzanol: A potential natural ingredient for skin care products," Journal of Natural Products, 2020.

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Dimethylaminoethanol Tartrate

Function: Emollient

1. Definition Dimethylaminoethanol Tartrate:

Dimethylaminoethanol Tartrate, also known as DMAE Tartrate, is a compound derived from the amino acid choline. It is commonly used in skincare products for its potential anti-aging and skin-firming properties.

2. Use:

DMAE Tartrate is often included in skincare formulations for its ability to improve skin tone and firmness. It is believed to help reduce the appearance of fine lines and wrinkles, as well as improve overall skin texture. DMAE Tartrate is commonly found in anti-aging creams, serums, and lotions.

3. Usage Dimethylaminoethanol Tartrate:

When using skincare products containing DMAE Tartrate, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential sensitivity or allergic reactions. DMAE Tartrate should be used as directed and should not be applied to broken or irritated skin.

4. References:

- Perricone, N. V. (2007). The Perricone Promise: Look Younger, Live Longer in Three Easy Steps. Grand Central Life & Style.

- Lupo, M. P. (2007). Cosmeceutical Critique: DMAE. Journal of Drugs in Dermatology, 6(7), 796-798.

- Grossman, R. M. (2005). The Skin Commandments: 10 Rules to Healthy, Beautiful Skin. Fair Winds Press.

Resveratrol

Function: Skin Protecting, Antioxidant

1. Definition Resveratrol:

Resveratrol is a natural compound found in various plants, such as grapes, berries, and peanuts. It is known for its antioxidant properties and has been shown to have potential anti-aging and skin-protecting benefits.

2. Use:

Resveratrol is commonly used in cosmetic products for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It can also help improve the overall appearance of the skin by reducing the appearance of fine lines and wrinkles, promoting collagen production, and brightening the complexion.

3. Usage Resveratrol:

When using products containing Resveratrol, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin. It is also important to use sunscreen when using Resveratrol products, as it can make the skin more sensitive to the sun.

4. References:

- Lin, J.K., Lin-Shiau, S.Y., & Juan, I.M. (2003). Survey of resveratrol contents in grape products and its consumption in Taiwan. Journal of Food and Drug Analysis, 11(2), 177-183.

- Sharma, S., & Anand, S. (2018). Role of Resveratrol in Prevention and Therapy of Cancer: Preclinical and Clinical Studies. Anticancer Agents in Medicinal Chemistry, 18(13), 1850-1861.

- Fauconneau, B., Waffo-Teguo, P., Huguet, F., Barrier, L., Decendit, A., & Merillon, J.M. (1997). Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests. Life Sciences, 61(21), 2103-2110.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Camellia Sinensis Leaf Extract

Function: Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.