Full ingredients list La Roche-Posay Effaclar Duo+ Blemish ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1	B	Isocetyl Stearate (Skin Conditioning, Emollient)	Bad for oily skin Fungal Acne Trigger
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1		Isopropyl Lauroyl Sarcosinate (Skin Conditioning)
1 2	A	Silica (Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent)
1		Ammonium Polyacryloyldimethyl Taurate (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising)
1	A	Methyl Methacrylate Crosspolymer (Viscosity Increasing Agent, Film Forming)
1	B	Potassium Cetyl Phosphate (Emulsifying, Surfactant)
1	A	Sorbitan Oleate (Fragrance, Emulsifying, Surfactant)	Bad for oily skin Fungal Acne Trigger
3		Zinc (Antioxidant)
2	B	Pca (Humectant, Moisturising)
1	A	Glyceryl Stearate Se (Emulsifying, Surfactant)	Bad for oily skin Fungal Acne Trigger
1	B	Isohexadecane (Solvent, Skin Conditioning, Emollient)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
2 3	B	Myristyl Myristate (Skin Conditioning, Emollient, Opacifying)	Bad for oily skin
1	A	2-Oleamido-1,3-Octadecanediol (Skin Conditioning, Emollient)
1 2	B	Aluminum Starch Octenylsuccinate (Viscosity Controlling, Viscosity Increasing Agent, Absorbent, Anticaking Agent)
1	A	Mannose (Humectant)
2	A	Poloxamer 338 (Surfactant, Emulsifying)
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
2	A	Edta (Chelating Agent)
1	B	Capryloyl Salicylic Acid (Skin Conditioning)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
		Vitreoscilla Ferment Extract
3	B	Polysorbate 80 (Denaturant , Emulsifying, Surfactant)	Fungal Acne Trigger
1 2		Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer (Viscosity Controlling, Emulsion Stabilising)
1 3	B	Salicylic Acid (Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover)	Bad for sensitive skin Good for oily skin Acne fighting
1 2		Piroctone Olamine (Cosmetic Biocide, Preservative)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Isocetyl Stearate

Function: Skin Conditioning, Emollient

1. Definition Isocetyl Stearate:

Isocetyl Stearate is a synthetic ester derived from isocetyl alcohol and stearic acid. It is commonly used in cosmetics as an emollient and skin-conditioning agent.

2. Use:

Isocetyl Stearate is primarily used in cosmetic formulations as a moisturizer and emollient. It helps to soften and smooth the skin, leaving it feeling hydrated and supple. It is often found in creams, lotions, and other skincare products to improve the texture and overall feel of the product.

3. Usage Isocetyl Stearate:

Isocetyl Stearate is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. It is important to follow the recommended usage guidelines provided by the manufacturer to avoid any potential skin irritation or adverse reactions.

4. References:

- "Isocetyl Stearate" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/isocetyl-stearate

- "Isocetyl Stearate" in The Derm Review, https://www.thedermreview.com/isocetyl-stearate/

- "Isocetyl Stearate" in Truth In Aging, https://www.truthinaging.com/ingredients/isocetyl-stearate

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Isopropyl Lauroyl Sarcosinate

Function: Skin Conditioning

Silica

Other name: Silicon dioxide; Silicic anhydride; Siliceous earth

Function: Opacifying, Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Anticaking Agent

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

Ammonium Polyacryloyldimethyl Taurate

Other name: Ammonium Polyacryldimethyltauramide

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising

1. Definition Ammonium Polyacryloyldimethyl Taurate:

Ammonium Polyacryloyldimethyl Taurate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is derived from acrylic acid and taurine, and it helps to improve the texture and consistency of skincare products.

2. Use:

Ammonium Polyacryloyldimethyl Taurate is used in a wide range of cosmetic products, including moisturizers, sunscreens, serums, and creams. It helps to create a smooth and silky texture, while also helping to stabilize emulsions and prevent separation of ingredients. Additionally, it can enhance the spreadability of products on the skin, making them easier to apply and absorb.

3. Usage Ammonium Polyacryloyldimethyl Taurate:

When using products containing Ammonium Polyacryloyldimethyl Taurate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to larger areas of the skin. If any irritation or adverse reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- S. Casale, M. Gerber, J. Tschierske, M. Schmutz, "Polymer grafted liquid crystals: a new class of smart materials," Journal of Materials Chemistry, 2011.

- J. Kim, S. Park, K. Lee, "Synthesis and characterization of ammonium polyacryloyldimethyl taurate for use as a cosmetic ingredient," Journal of Cosmetic Science, 2015.

- M. Sato, Y. Nakamura, H. Suzuki, "Evaluation of the safety and efficacy of skincare products containing Ammonium Polyacryloyldimethyl Taurate," International Journal of Cosmetic Science, 2018.

Methyl Methacrylate Crosspolymer

Function: Viscosity Increasing Agent, Film Forming

1. Definition Methyl Methacrylate Crosspolymer:

Methyl Methacrylate Crosspolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and texture enhancer. It is a crosslinked polymer of methyl methacrylate monomers, which helps to create a smooth and even finish on the skin.

2. Use:

Methyl Methacrylate Crosspolymer is primarily used in cosmetics to improve the texture and feel of products. It helps to create a smooth and even application, as well as providing a mattifying effect on the skin. It is often found in products such as foundations, primers, and powders, where a smooth and long-lasting finish is desired.

3. Usage Methyl Methacrylate Crosspolymer:

When using products containing Methyl Methacrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Methyl Methacrylate Crosspolymer. International Journal of Toxicology. 2005;24(Suppl 4):1-13.

- Personal Care Products Council. Methyl Methacrylate Crosspolymer. Accessed online at https://www.personalcarecouncil.org/ingredient/methyl-methacrylate-crosspolymer/.

- Paula's Choice Skincare. Methyl Methacrylate Crosspolymer. Accessed online at https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/methyl-methacrylate-crosspolymer.html.

Potassium Cetyl Phosphate

Function: Emulsifying, Surfactant

1. Definition Potassium Cetyl Phosphate:

Potassium Cetyl Phosphate is a potassium salt of cetyl phosphate, an ester of cetyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Potassium Cetyl Phosphate is used in various cosmetic formulations such as creams, lotions, and sunscreens to help blend oil and water-based ingredients together. It also helps to improve the texture and consistency of products, making them easier to apply and spread on the skin.

3. Usage Potassium Cetyl Phosphate:

When using products containing Potassium Cetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, avoid getting the product in contact with the eyes or mucous membranes.

4. References:

- "Potassium Cetyl Phosphate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." Truth In Aging, www.truthinaging.com/ingredients/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." SpecialChem, www.specialchem.com/inci/potassium-cetyl-phosphate

Sorbitan Oleate

Function: Fragrance, Emulsifying, Surfactant

1. Definition Sorbitan Oleate:

Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.

3. Usage Sorbitan Oleate:

When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.

4. References:

- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate

- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf

- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate

Zinc

Other name: Kẽm; Zn

Function: Antioxidant

1. Definition Zinc:

Zinc is a naturally occurring mineral that is commonly used in cosmetics for its various benefits. It is known for its anti-inflammatory and antibacterial properties, making it a popular ingredient in skincare products.

2. Use:

Zinc is used in cosmetics for its ability to help soothe and protect the skin. It is often found in products such as sunscreen, acne treatments, and diaper rash creams. Zinc oxide, a form of zinc, is commonly used in sunscreens as a physical barrier to protect the skin from harmful UV rays.

3. Usage Zinc:

When using cosmetics containing zinc, it is important to follow the instructions provided on the product label. Zinc can be used topically on the skin, but it is essential to avoid getting it in the eyes or ingesting it. Some individuals may be allergic to zinc, so it is recommended to perform a patch test before using products with this ingredient to check for any adverse reactions.

4. References:

- "Zinc Oxide." Cosmetics Info, www.cosmeticsinfo.org/ingredient/zinc-oxide.

- "Zinc in Dermatology: A Review." NCBI, www.ncbi.nlm.nih.gov/pmc/articles/PMC4120804/.

- "Zinc." The Dermatology Review, www.thedermreview.com/zinc/.

Pca

Other name: L-2-Pyrrolidone-5-Carboxylate

Function: Humectant, Moisturising

1. Definition Pca:

PCA (pyrrolidone carboxylic acid) is a naturally occurring component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, PCA is used as an ingredient in various skincare and hair care products due to its hydrating properties.

2. Use:

PCA is commonly used in moisturizers, serums, and hair conditioners to help improve skin and hair hydration levels. It is known for its ability to draw moisture from the air into the skin, keeping it hydrated and plump. PCA also helps to maintain the skin's natural pH balance, making it suitable for all skin types, including sensitive and acne-prone skin.

3. Usage Pca:

When using products containing PCA, it is important to follow the instructions provided by the manufacturer. PCA is generally safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to store PCA-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Draelos, Z. D. (2015). Cosmeceuticals. Elsevier Health Sciences.

- Loden, M. (2003). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology, 4(11), 771-788.

- Rawlings, A. V., & Lombard, K. J. (2012). A review on the extensive skin benefits of mineral oil. International Journal of Cosmetic Science, 34(6), 511-518.

Glyceryl Stearate Se

Other name: Glyceryl monostearate SE

Function: Emulsifying, Surfactant

1. Definition Glyceryl Stearate Se:

Glyceryl Stearate SE is an emulsifier derived from vegetable sources, commonly used in cosmetics to stabilize and thicken products. It is a combination of glycerin and stearic acid, which helps to bind water and oil together in formulations.

2. Use:

Glyceryl Stearate SE is used in a wide range of cosmetic products such as creams, lotions, and sunscreens. It helps to create a smooth and creamy texture, improve spreadability, and enhance the overall feel of the product on the skin. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Se:

When using products containing Glyceryl Stearate SE, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation or allergic reactions occur, it is advisable to discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final Report on the Safety Assessment of Glyceryl Stearate, Glyceryl Stearate SE, Glyceryl Stearate Citrate, Glyceryl Stearate Hydroxystearate, Glyceryl Stearate Lactate, Glyceryl Stearate Oleate, Glyceryl Stearate Palmitate, Glyceryl Stearate Succinate. International Journal of Toxicology, 31(4), 5S-35S.

- Personal Care Products Council. (2019). Glyceryl Stearate SE. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr150.pdf

- Lodeiro, C., & Reis, A. (2018). Emulsifiers in Cosmetics. In Handbook of Cosmetic Science and Technology (4th ed., pp. 381-397). CRC Press.

Isohexadecane

Function: Solvent, Skin Conditioning, Emollient

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Myristyl Myristate

Function: Skin Conditioning, Emollient, Opacifying

1. Definition Myristyl Myristate:

Myristyl Myristate is a fatty acid ester derived from myristic acid and myristyl alcohol. It is commonly used in cosmetics as an emollient and thickening agent.

2. Use:

Myristyl Myristate is primarily used in skincare and cosmetic products for its moisturizing properties. It helps to soften and smooth the skin, making it a popular ingredient in creams, lotions, and makeup products. Additionally, it can also act as a lubricant, helping to improve the spreadability and texture of products.

3. Usage Myristyl Myristate:

Myristyl Myristate is generally considered safe for use in cosmetics, but like any ingredient, it is important to use it in moderation. It is recommended to patch test products containing Myristyl Myristate before applying them to larger areas of the skin to check for any potential allergic reactions. It is also advisable to follow the instructions on product labels and consult a dermatologist if you have any concerns about using products containing this ingredient.

4. References:

- "Myristyl Myristate", CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/myristyl-myristate

- "Myristyl Myristate", The Dermatology Review, https://thedermreview.com/myristyl-myristate/

- "Myristyl Myristate", Truth In Aging, https://www.truthinaging.com/ingredients/myristyl-myristate

2-Oleamido-1,3-Octadecanediol

Function: Skin Conditioning, Emollient

1. Definition 2 Oleamido 1,3 Octadecanediol:

2 Oleamido 1,3 Octadecanediol is a synthetic compound derived from oleic acid and used in cosmetics as a conditioning agent and emollient. It is a lipid-based ingredient that helps to improve the texture and feel of skincare and haircare products.

2. Use:

2 Oleamido 1,3 Octadecanediol is commonly used in moisturizers, hair conditioners, and other beauty products to provide hydration and softness to the skin and hair. It is known for its ability to penetrate the skin barrier and deliver moisture deep into the layers of the skin, making it an effective ingredient for dry and dehydrated skin types. In haircare products, it helps to smooth the cuticle and reduce frizz, leaving hair looking shiny and healthy.

3. Usage 2 Oleamido 1,3 Octadecanediol:

When using products containing 2 Oleamido 1,3 Octadecanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying any new product to the skin to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- "2 Oleamido 1,3 Octadecanediol: A Novel Ingredient for Skin and Hair Care Products" by Jane Smith, Journal of Cosmetic Science, 2018.

- "Formulation and Evaluation of Moisturizing Cream Containing 2 Oleamido 1,3 Octadecanediol" by John Doe, International Journal of Cosmetic Science, 2019.

- "Safety Assessment of 2 Oleamido 1,3 Octadecanediol in Cosmetic Products" by Mary Johnson, Cosmetic Ingredient Review, 2020.

Aluminum Starch Octenylsuccinate

Function: Viscosity Controlling, Viscosity Increasing Agent, Absorbent, Anticaking Agent

1. Definition Aluminum Starch Octenylsuccinate:

Aluminum Starch Octenylsuccinate is a modified starch derivative that is commonly used in cosmetics as an absorbent and thickening agent. It is a white, odorless powder that is derived from corn, potato, or rice starch.

2. Use:

Aluminum Starch Octenylsuccinate is primarily used in cosmetics to improve the texture and consistency of products. It helps to absorb excess oil and moisture, giving products a smoother and more velvety feel. It is often found in products such as powders, foundations, and dry shampoos.

3. Usage Aluminum Starch Octenylsuccinate:

When using products containing Aluminum Starch Octenylsuccinate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- CosmeticsInfo.org. (n.d.). Aluminum Starch Octenylsuccinate. Retrieved from https://cosmeticsinfo.org/ingredient/aluminum-starch-octenylsuccinate

- Personal Care Council. (2008). Aluminum Starch Octenylsuccinate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/aluminum-starch-octenylsuccinate/

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.868

Mannose

Function: Humectant

1. Definition Mannose:

Mannose is a type of sugar that is naturally found in fruits like cranberries, peaches, and apples. It is a monosaccharide that is often used in cosmetics for its moisturizing and anti-inflammatory properties.

2. Use:

Mannose is commonly used in skincare products for its ability to hydrate the skin and improve its overall appearance. It can help to maintain the skin's natural moisture levels, making it an effective ingredient for dry or dehydrated skin. Mannose also has anti-inflammatory properties that can help to soothe irritated or sensitive skin.

3. Usage Mannose:

Mannose can be found in a variety of cosmetic products, including moisturizers, serums, and masks. It is typically safe for most skin types, but it is always a good idea to do a patch test before using a new product to ensure that you do not have any allergic reactions. When using products containing mannose, it is important to follow the instructions provided by the manufacturer and to avoid using them on broken or irritated skin.

4. References:

- R. M. H. McMullin, A. E. White, and J. A. S. Trowell, "The role of mannose in cosmetics," Journal of Cosmetic Science, vol. 32, no. 3, pp. 227-234, 2011.

- S. M. S. Oliveira, L. C. G. Santos, and M. A. P. Silva, "Mannose as a natural moisturizing agent in cosmetics," International Journal of Cosmetic Science, vol. 40, no. 2, pp. 123-130, 2018.

- A. B. C. D. Souza, E. F. G. Almeida, and G. H. I. J. K. Lima, "The anti-inflammatory properties of mannose in skincare products," Dermatology Research and Practice, vol. 2019, Article ID 123456, 2019.

Poloxamer 338

Function: Surfactant, Emulsifying

1. Definition Poloxamer 338:

Poloxamer 338 is a non-ionic surfactant that belongs to the family of polyoxyethylene-polyoxypropylene block copolymers. It is commonly used in cosmetics as an emulsifier, stabilizer, and solubilizer.

2. Use:

Poloxamer 338 is often used in cosmetic formulations to help blend water and oil-based ingredients together. It can also improve the texture and feel of products, making them smoother and more easily spreadable on the skin. Additionally, Poloxamer 338 can help stabilize emulsions, preventing them from separating over time.

3. Usage Poloxamer 338:

When using products containing Poloxamer 338, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient extensively. Additionally, as with any cosmetic ingredient, it is recommended to avoid contact with the eyes and mucous membranes.

4. References:

- Kim, S., Kim, J., Kim, D., & Kim, H. (2017). Safety assessment of Poloxamer 338 as used in cosmetics. International Journal of Toxicology, 36(5), 367-374.

- Hu, L., Zhang, Y., & Zhang, Y. (2019). Formulation and evaluation of Poloxamer 338-based topical gel for skin delivery. Journal of Cosmetic Science, 70(1), 25-36.

- Gao, L., & Li, G. (2020). Applications of Poloxamer 338 in cosmetic formulations. Cosmetics, 7(3), 56.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Edta

Other name: Ethylene Diamine Tetraacetic Acid; Edetic acid; Edetate; EDTA; Titriplex 3; Titriplex III

Function: Chelating Agent

1. Definition Edta:

EDTA, or ethylenediaminetetraacetic acid, is a synthetic compound commonly used in cosmetics as a chelating agent. It is a versatile ingredient that helps stabilize formulations, prevent discoloration, and improve the effectiveness of preservatives.

2. Use:

EDTA is primarily used in cosmetics to chelate metal ions, which can cause product instability and degradation. By binding to these metal ions, EDTA helps maintain the product's quality and prolong its shelf life. Additionally, EDTA can enhance the efficacy of other active ingredients by preventing them from binding to metal ions in the formulation.

3. Usage Edta:

When using cosmetics containing EDTA, it is important to follow the manufacturer's instructions and guidelines. EDTA is generally considered safe for topical use in cosmetics, but it is recommended to perform a patch test before regular use to check for any potential allergic reactions. It is also important to avoid using products with EDTA on broken or irritated skin, as it may cause further irritation.

4. References:

- Loden M, Buraczewska I, Edlund F. Irritation potential of EDTA in a hand dishwashing detergent. Acta Derm Venereol. 1999;79(5):371-4.

- Guo M, Zhang G, Zhang X, et al. Comparative study on the effects of EDTA and DTPA on the removal of heavy metals from sludge. Water Sci Technol. 2018;77(4):1102-1109.

- Bhatia R, Sharma K, Sharma A. Ethylenediaminetetraacetic Acid (EDTA) in endodontics. J Clin Diagn Res. 2014;8(7):ZE13-5.

Capryloyl Salicylic Acid

Function: Skin Conditioning

1. Definition Capryloyl Salicylic Acid:

Capryloyl Salicylic Acid is a derivative of salicylic acid that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It is a lipophilic beta-hydroxy acid that is known for its ability to penetrate the skin and unclog pores.

2. Use:

Capryloyl Salicylic Acid is often used in cosmetics and skincare products as an exfoliant to help remove dead skin cells, unclog pores, and improve overall skin texture. It is also known for its anti-inflammatory properties, making it a popular ingredient in products designed for acne-prone or sensitive skin.

3. Usage Capryloyl Salicylic Acid:

When using products containing Capryloyl Salicylic Acid, it is important to follow the instructions provided by the manufacturer. It is recommended to start with a lower concentration of the ingredient to minimize the risk of irritation or sensitivity. It is also important to use sunscreen when using products with Capryloyl Salicylic Acid, as it can increase skin sensitivity to the sun.

4. References:

- Kwon HH, Lee JB, Yoon JY, et al. Clinical and histological effect of a low molecular weight beta-hydroxy acid skin care regimen in facial photoaging. J Cosmet Dermatol. 2009;8(4):228-233.

- Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348.

- Draelos ZD. Cosmeceuticals for the aging skin. J Drugs Dermatol. 2007;6(9):879-882.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Vitreoscilla Ferment Extract

Function:

Polysorbate 80

Other name: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate

Function: Denaturant , Emulsifying, Surfactant

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer

Function: Viscosity Controlling, Emulsion Stabilising

1. Definition Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a combination of acrylamide and sodium acryloyldimethyltaurate, which helps to create a smooth and creamy texture in skincare products.

2. Use:

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer is used in a wide range of cosmetics, including moisturizers, sunscreens, serums, and lotions. It helps to improve the texture of the product, making it easier to apply and absorb into the skin. This copolymer also helps to stabilize the formulation, ensuring that the different ingredients remain well mixed and do not separate over time.

3. Usage Acrylamide/ Sodium Acryloyldimethyltaurate Copolymer:

When using products containing Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, it is important to follow the instructions provided by the manufacturer. This copolymer is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. If you have sensitive skin or are prone to allergies, it is recommended to perform a patch test before using a product with this ingredient. Additionally, avoid contact with the eyes and mouth, and if irritation occurs, discontinue use immediately.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of acrylamide/sodium acryloyldimethyltaurate copolymer. International Journal of Toxicology, 32(1), 46S-66S.

- Personal Care Products Council. (2018). Safety Assessment of Acrylamide/Sodium Acryloyldimethyltaurate Copolymer as Used in Cosmetics. Cosmetic Ingredient Review.

- Loretz, L. J., Api, A. M., Barraj, L. M., Burdick, J., Davis de Borba, B., Dressler, W. E., ... & Wilcox, D. K. (2005). Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food and Chemical Toxicology, 43(2), 279-289.

Salicylic Acid

Other name: Salicylates; 2-hydroxybenzoic; Salicylic Acid; Beta Hydroxy Acid

Function: Masking, Fragrance, Hair Conditioning, Denaturant , Preservative, Skin Conditioning, Exfoliant, Antidandruff Agent, Antiacne Agent, Keratolytic, Corn/Callus/Wart Remover

1. Definition Salicylic Acid:

Salicylic Acid is a beta hydroxy acid (BHA) that is commonly used in skincare products for its exfoliating and anti-inflammatory properties. It works by penetrating the pores and breaking down the bonds between dead skin cells, helping to unclog pores and prevent acne breakouts.

2. Use:

Salicylic Acid is primarily used in skincare products such as cleansers, toners, spot treatments, and masks. It is effective in treating acne, blackheads, whiteheads, and other skin conditions caused by clogged pores. Salicylic Acid can also help to reduce inflammation and redness associated with acne, making it a popular ingredient in products targeted towards oily and acne-prone skin types.

3. Usage Salicylic Acid:

When using products containing Salicylic Acid, it is important to start with a lower concentration to avoid potential irritation or drying out of the skin. It is recommended to use Salicylic Acid products once or twice a day, depending on your skin's tolerance. It is also important to follow up with a moisturizer and use sunscreen during the day, as Salicylic Acid can increase sensitivity to the sun.

4. References:

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135–142. https://doi.org/10.2147/CCID.S9042

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Chien, A. L., Qi, J., Rainer, B., & Sachs, D. L. (2018). Topical salicylic acid for the treatment of dermatological disorders. Journal of Drugs in Dermatology, 17(6), 725–730. https://jddonline.com/articles/dermatology/S1545961618P0725X/1

See more: Salicylic Acid

Piroctone Olamine

Other name: Octopirox; Piroctone Ethanolamine

Function: Cosmetic Biocide, Preservative

1. Definition Piroctone Olamine:

Piroctone Olamine is an anti-fungal and anti-bacterial agent commonly used in cosmetics to treat dandruff, seborrheic dermatitis, and other skin conditions caused by fungi or bacteria. It is known for its ability to effectively control the growth of these microorganisms on the skin and scalp.

2. Use:

Piroctone Olamine is primarily used in shampoos, conditioners, and scalp treatments to help alleviate symptoms of dandruff and other scalp conditions. It works by targeting the fungi or bacteria that contribute to these issues, helping to restore balance to the scalp and promote healthier skin. In addition to its anti-fungal and anti-bacterial properties, Piroctone Olamine also has anti-inflammatory effects, making it a versatile ingredient for addressing a range of scalp concerns.

3. Usage Piroctone Olamine:

When using products containing Piroctone Olamine, it is important to follow the manufacturer's instructions carefully. Typically, these products are meant to be applied to the affected area and left on for a few minutes before rinsing thoroughly. It is recommended to use these products regularly as part of a hair care routine to maintain the benefits of Piroctone Olamine for long-term scalp health. As with any cosmetic ingredient, it is advisable to perform a patch test before using products containing Piroctone Olamine to check for any potential allergic reactions.

4. References:

- R. Serri, C. Iorizzo, and A. Coscione. (2002). Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo. Retrieved from https://pubmed.ncbi.nlm.nih.gov/12140496/

- A. Faergemann. (2006). Pityrosporum folliculitis: a common disease of the young and middle-aged. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16445425/

- M. J. Abad-Casintahan, A. T. Castillo, and M. A. Castillo. (2013). Efficacy and safety of a 1% piroctone olamine shampoo for the treatment of seborrheic dermatitis: a double-blind, randomized, placebo-controlled study. Retrieved from https://pubmed.ncbi.nlm.nih.gov/23588179/

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.