Full ingredients list Laikou Japan Sakur Eye Mask

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
3	B	Propylene Glycol (Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous)	Good for dry skin
1		Chondrus Crispus (Carrageenan)
1		Ceratonia Siliqua Gum (Masking, Emollient, Viscosity Controlling, Emulsion Stabilising, Binding, Film Forming)
1	A	Agar (Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding)
1	A	Cyamopsis Tetragonoloba (Guar) Gum (Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming)
1		Hydroxyacetophenone (Antioxidant)
1	A	1,2-Hexanediol (Solvent)
1		Potassium Chloride (Viscosity Controlling, Viscosity Increasing Agent)	Bad for oily skin
1		Calcium Chloride (Viscosity Controlling, Viscosity Increasing Agent, Cosmetic Astringent)
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
3 4	A	Methylparaben (Fragrance, Preservative)	Paraben
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
1 4	B	Sodium Hydroxide (Denaturant , pH adjusting agent, pH adjusting agent)
1 3		Titanium Dioxide (Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying)	UV Protection Good for sensitive skin
5		CI 16255 (Cosmetic Colorant)
3		Peg/ Ppg 17/ 6 Copolymer (Solvent)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	Hydrolyzed Collagen (Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents)
1		Prunus Speciosa Flower Extract (Skin Conditioning)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1		Sargassum Fusiforme Extract (Skin Conditioning)
1		Hydrolyzed Pearl (Skin Conditioning)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1		Acetyl Tetrapeptide 5 (Humectant)
1		Glycine Soja (Soybean) Seed Extract (Solvent, Skin Conditioning, Emollient, Hair Conditioning, Bulking Agent, Moisturising)	Anti Aging Good for dry skin
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Hydroxyethylcellulose (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming)
1 3	B	Peg 40 Hydrogenated Castor Oil (Perfuming, Fragrance, Emulsifying, Surfactant)	Fungal Acne Trigger
2 4	A	Phenoxyethanol (Fragrance, Preservative)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
8		Fragrance (Masking, Perfuming, Deodorant)	Good for dry skin

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Propylene Glycol

Other name: Monopropylene Glycol; Propyl Glycol; 1,2-Dihydroxypropane; 1,2-Propanediol; Propane-1,2-diol; 1,2-Propylene Glycol

Function: Solvent, Fragrance, Humectant, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling, Skin-Conditioningagent - Miscellaneous

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

Chondrus Crispus (Carrageenan)

Function:

1. Definition Chondrus Crispus (Carrageenan):

Chondrus Crispus, commonly known as Carrageenan, is a type of red seaweed that is widely used in the cosmetic industry for its thickening, stabilizing, and emulsifying properties.

2. Use:

Carrageenan is used in cosmetics to improve the texture, consistency, and stability of products such as lotions, creams, and gels. It helps to create a smooth and creamy texture, while also preventing the separation of ingredients in formulations.

3. Usage Chondrus Crispus (Carrageenan):

Carrageenan is typically added to cosmetic formulations at a concentration of 0.1% to 2%. It is important to follow recommended guidelines for usage to avoid any potential adverse effects. Carrageenan is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient.

4. References:

- Draget, K.I., Skjak-Braek, G., and Smidsrod, O. (2006). Alginates from Algae. In: Steinbuchel, A., ed. Biopolymers, Volume 6: Polysaccharides II: Polysaccharides from Eukaryotes. Wiley-VCH Verlag GmbH & Co. KGaA.

- Lopes, G., Sousa, C., Silva, L.R., Pinto, E., and Andrade, P.B. (2012). Chapter 9: Seaweeds as Preventive Agents for Skin Disorders. In: Kim, S.K., ed. Handbook of Anticancer Drugs from Marine Origin. Springer.

- De Jesus Raposo, M.F., De Morais, R.M.S.C., and De Morais, A.M.M.B. (2013). Bioactivity and Applications of Sulphated Polysaccharides from Marine Microalgae. Marine Drugs, 11(1), 233-252.

Ceratonia Siliqua Gum

Other name: Carob bean Gum

Function: Masking, Emollient, Viscosity Controlling, Emulsion Stabilising, Binding, Film Forming

1. Definition Ceratonia Siliqua Gum:

Ceratonia Siliqua Gum, also known as carob gum or locust bean gum, is a natural thickening agent derived from the seeds of the carob tree. It is commonly used in cosmetics as a stabilizer, emulsifier, and viscosity enhancer.

2. Use:

Ceratonia Siliqua Gum is used in cosmetics to improve the texture and consistency of products such as creams, lotions, and gels. It helps to create a smooth and creamy texture while also providing a moisturizing effect on the skin. Additionally, it can help to stabilize emulsions and prevent separation of ingredients in formulations.

3. Usage Ceratonia Siliqua Gum:

When using Ceratonia Siliqua Gum in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. Overuse of this ingredient can result in a thick and sticky texture, which may not be desirable in certain formulations. It is also important to properly disperse the gum in the formulation to ensure even distribution and optimal performance.

Precautions: While Ceratonia Siliqua Gum is generally considered safe for use in cosmetics, individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have a history of skin sensitivities.

4. References:

- M. P. López-Rubio, M. A. Lagaron, M. Anker, and R. Wittkowski. 2004. "Functional properties of sodium caseinate–carob germ protein conjugates obtained by Maillard reaction." Journal of Agricultural and Food Chemistry 52(18): 5793-5800.

- M. A. Lagaron, M. P. López-Rubio, and R. Wittkowski. 2006. "Interfacial and emulsifying properties of sodium caseinate–carob germ protein conjugates obtained by the Maillard reaction." Journal of Agricultural and Food Chemistry 54(5): 1729-1736.

- S. S. Anand and R. N. Tharanathan. 2005. "Chitin/chitosan: modifications and their unlimited application potential—an overview." Trends in Food Science & Technology 16(10): 521-535.

Agar

Other name: agal-agal; Ceylon agar; Agar

Function: Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Binding Agent, Binding

1. Definition Agar:

Agar is a gelatinous substance derived from seaweed, specifically red algae. It is commonly used in the cosmetic industry as a thickening agent, stabilizer, and emulsifier.

2. Use:

Agar is used in cosmetics to create a smooth and creamy texture in products such as lotions, creams, and gels. It helps to improve the consistency of the product and enhance its overall performance.

3. Usage Agar:

When using agar in cosmetics, it is important to follow the recommended guidelines for incorporating it into the formulation. Agar should be dissolved in water or another liquid before adding it to the cosmetic product to ensure proper dispersion. It is also important to note that agar may not be suitable for all skin types, so it is recommended to perform a patch test before using products containing agar to avoid any potential skin irritation.

4. References:

- Gu, Y., Yang, J., & Luo, J. (2019). Agar hydrogel properties for skin care applications. International Journal of Biological Macromolecules, 125, 258-265.

- Patel, S., Majumder, A., & Goyal, A. (2012). Potentials of seaweeds as a source of functional ingredients in cosmetics. A review. Journal of Applied Phycology, 24(3), 525-536.

- Jana, A., & Halder, B. (2019). Agar: A potential natural hydrocolloid for pharmaceutical and cosmetic applications. International Journal of Biological Macromolecules, 121, 1169-1178.

Cyamopsis Tetragonoloba (Guar) Gum

Other name: Guar Symbiosome Extract; Cyamopsis Tetragonoloba Symbiosome Extract; Cyamopsis Tetragonoloba Gum

Function: Masking, Fragrance, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Film Forming

1. Definition Cyamopsis Tetragonoloba (Guar) Gum:

Cyamopsis Tetragonoloba (Guar) Gum is a natural plant-based ingredient derived from the seeds of the guar plant. It is a water-soluble polysaccharide that is commonly used as a thickening agent, stabilizer, and emulsifier in various cosmetic formulations.

2. Use:

Guar gum is widely used in cosmetics for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in lotions, creams, and gels, and can also enhance the spreadability of formulations. Guar gum is often used in hair care products such as shampoos and conditioners to provide conditioning benefits and improve the manageability of the hair.

3. Usage Cyamopsis Tetragonoloba (Guar) Gum:

Guar gum should be used in cosmetics according to the recommended usage levels provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing guar gum to ensure they do not experience any adverse reactions. Additionally, it is important to properly disperse guar gum in water before adding it to formulations to prevent clumping and ensure even distribution.

4. References:

- Sharma, P., & Sharma, S. (2012). Evaluation of guar gum as a binder in the formulation of metronidazole tablets. International Journal of Pharmacy and Pharmaceutical Sciences, 4(3), 515-520.

- Amin, M. C. I. M., Ahmad, N., & Halib, N. (2015). Guar gum as potential natural polymer for the development of floating drug delivery systems: A review. Journal of Food and Drug Analysis, 23(4), 577-587.

- Shah, P., & Mishra, S. (2018). Plant-based natural gums and mucilages in pharmaceutical excipients and drug delivery systems. In Handbook of Polymers for Pharmaceutical Technologies (pp. 377-401). John Wiley & Sons.

Hydroxyacetophenone

Other name: SymSave H

Function: Antioxidant

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Potassium Chloride

Function: Viscosity Controlling, Viscosity Increasing Agent

1. Definition Potassium Chloride:

Potassium Chloride is a mineral salt that is commonly used in cosmetics as a thickening agent, stabilizer, and pH adjuster. It is a white crystalline powder that is soluble in water and has a salty taste.

2. Use:

Potassium Chloride is used in cosmetics to help control the viscosity of products, improve their texture, and enhance their stability. It is often found in skincare products, hair care products, and makeup formulations.

3. Usage Potassium Chloride:

Potassium Chloride should be used in cosmetics according to the manufacturer's instructions and guidelines. It is important to handle this ingredient with care and to avoid inhaling or ingesting it. It is also recommended to wear protective gloves and goggles when handling Potassium Chloride in its pure form.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 4873, Potassium Chloride. https://pubchem.ncbi.nlm.nih.gov/compound/Potassium-chloride

- Personal Care Council. Potassium Chloride. https://www.personalcarecouncil.org/ingredient-info/potassium-chloride/

- Cosmetic Ingredient Review. Final Report on the Safety Assessment of Potassium Chloride. https://www.cir-safety.org/sites/default/files/potchlor0314rep.pdf

Calcium Chloride

Function: Viscosity Controlling, Viscosity Increasing Agent, Cosmetic Astringent

1. Definition Calcium Chloride:

Calcium Chloride is a salt compound composed of calcium and chlorine. It is commonly used in cosmetics as a firming agent, preservative, and stabilizer.

2. Use:

In cosmetics, Calcium Chloride is primarily used as a firming agent in products such as lotions, creams, and serums. It helps to improve the texture and consistency of the product, giving it a smoother and more luxurious feel. Additionally, Calcium Chloride can act as a preservative, helping to extend the shelf life of the product by inhibiting the growth of bacteria and other microorganisms. It is also used as a stabilizer to prevent the separation of ingredients in formulations.

3. Usage Calcium Chloride:

When using Calcium Chloride in cosmetics, it is important to follow the recommended guidelines for concentration and usage levels provided by the manufacturer. Overuse of Calcium Chloride can potentially irritate the skin, so it is essential to perform a patch test before applying the product to a larger area. Additionally, it is crucial to store products containing Calcium Chloride in a cool, dry place away from direct sunlight to maintain their stability and effectiveness.

4. References:

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Ammonium, Potassium, and Sodium Persulfate, Ammonium, Potassium, and Sodium Persilicate, Ammonium, Potassium, and Sodium Pyrosulfate, and Ammonium, Potassium, and Sodium Pyrosilicate." International Journal of Toxicology 24 (2005): 5-35.

- "Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Aluminum Silicate, Calcium Silicate, Magnesium Aluminum Silicate, Magnesium Silicate, Magnesium Trisilicate, Sodium Magnesium Silicate, Zirconium Silicate, Attapulgite, Bentonite, Fuller's Earth, Hectorite, Kaolin, Lithium Magnesium Silicate, Lithium Magnesium Sodium Silicate, Montmorillonite, Pyrophyllite, and Zeolite. International Journal of Toxicology 22 (2003): 37-102.

Allantoin

Other name: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Methylparaben

Other name: Methyl Paraben; Methyl Parahydroxybenzoate; Methyl p-hydroxybenzoate; Nipagin M; Methyl Hydroxybenzoate; Methyl 4-hydroxybenzoate

Function: Fragrance, Preservative

1. Definition Methylparaben:

Methylparaben is a type of paraben, which is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is a white crystalline powder that is soluble in alcohol and slightly soluble in water.

2. Use:

Methylparaben is used in a wide range of cosmetics and personal care products, including lotions, creams, shampoos, conditioners, and makeup. It helps to extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Methylparaben:

Methylparaben is typically used at concentrations of 0.1% to 0.5% in cosmetics and personal care products. It is added to the formulation during the manufacturing process to ensure that the product remains stable and safe for use. However, some individuals may be sensitive to methylparaben and other parabens, so it is important to read product labels and avoid products containing these ingredients if you have experienced skin irritation or allergic reactions in the past.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report of the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(4), 1-82.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumers Directorate-General.

- Soni, M. G., Carabin, I. G., & Burdock, G. A. (2005). Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and Chemical Toxicology, 43(7), 985-1015.

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Sodium Hydroxide

Other name: NaOH

Function: Denaturant , pH adjusting agent, pH adjusting agent

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

Titanium Dioxide

Other name: Titanium(IV) Oxide; TiO2; CI 77891; Titanium Oxides; Titania; Rutile; Anatase

Function: Cosmetic Colorant, Uv Absorber, Sunscreen Agent, Opacifying

1. Definition Titanium Dioxide:

Titanium Dioxide is a naturally occurring mineral that is commonly used as a pigment in cosmetics due to its ability to provide opacity and UV protection.

2. Use:

Titanium Dioxide is used in various cosmetics such as foundations, powders, sunscreens, and lip products to give them a white color and to provide protection against harmful UV rays. It is also used as a thickening agent in some formulations.

3. Usage Titanium Dioxide:

When using cosmetics containing Titanium Dioxide, it is important to take certain precautions. Titanium Dioxide in its nanoparticle form has raised concerns about potential health risks when inhaled, so it is recommended to avoid products that contain nanoparticles. Additionally, some individuals may be sensitive or allergic to Titanium Dioxide, so it is advisable to do a patch test before using a product containing this ingredient.

4. References:

- Lademann, J., Weigmann, H. J., Rickmeyer, C., Barthelmes, H., Schaefer, H., & Mueller, G. (1999). Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, 12(5), 247-256.

- Tinkle, S. S., Antonini, J. M., Rich, B. A., Roberts, J. R., Salmen, R., DePree, K., ... & Adkins, E. J. (2003). Skin as a route of exposure and sensitization in chronic beryllium disease. Environmental Health Perspectives, 111(9), 1202-1208.

- Sadrieh, N., Wokovich, A. M., Gopee, N. V., Zheng, J., Haines, D., Parmiter, D., ... & Howard, P. C. (2010). Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles. Toxicological Sciences, 115(1), 156-166.

CI 16255

Other name: Acid Red 18

Function: Cosmetic Colorant

1. Definition CI 16255:

CI 16255, also known as Acid Red 18, is a synthetic colorant commonly used in cosmetics to add a red hue to various products.

2. Use:

CI 16255 is primarily used as a colorant in cosmetics, including lipsticks, blushes, eyeshadows, and nail polishes. It provides a vibrant red shade that enhances the overall appearance of the product.

3. Usage CI 16255:

When using cosmetics containing CI 16255, it is important to follow the manufacturer's instructions and recommendations. It is advised to perform a patch test on a small area of skin before applying the product to ensure there are no allergic reactions or sensitivities. Additionally, individuals with sensitive skin or skin conditions should consult with a dermatologist before using products with CI 16255 to avoid any potential irritation.

4. References:

- "Safety Assessment of CI 16255 (Acid Red 18) and Acid Orange 7" by the Cosmetic Ingredient Review Expert Panel

- "Color Additives Permitted for Use in Cosmetics" by the U.S. Food and Drug Administration

- "Toxicological Evaluation of Some Food Additives Including Anticaking Agents, Antimicrobials, Antioxidants, Emulsifiers, and Thickening Agents" by the World Health Organization

Peg/ Ppg 17/ 6 Copolymer

Function: Solvent

1. Definition Peg/ Ppg 17/ 6 Copolymer:

Peg/ Ppg 17/ 6 Copolymer is a copolymer derived from the reaction of polyethylene glycol (PEG) and polypropylene glycol (PPG) with a molecular weight of 17 for PEG and 6 for PPG. It is commonly used in cosmetics as an emulsifier, surfactant, and viscosity controlling agent.

2. Use:

Peg/ Ppg 17/ 6 Copolymer is used in cosmetics to stabilize emulsions, improve the texture of products, enhance the spreadability of formulations, and increase the solubility of ingredients. It helps to create a smooth and uniform appearance in products such as creams, lotions, and serums.

3. Usage Peg/ Ppg 17/ 6 Copolymer:

Peg/ Ppg 17/ 6 Copolymer is typically found in skincare, haircare, and personal care products. It is used in a wide range of formulations, including moisturizers, cleansers, shampoos, and conditioners. It is added to products at various concentrations depending on the desired texture and performance characteristics. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient.

4. References:

- "PEG/PPG-17/6 Copolymer" by Cosmeticsinfo.org

- "Polyethylene Glycol (PEG) and Polypropylene Glycol (PPG) Market Analysis" by Grand View Research

- "Safety Assessment of PEG/PPG-17/6 Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Hydrolyzed Collagen

Other name: Hydrolyzed animal protein

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Film Forming, Nail Agents

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

Prunus Speciosa Flower Extract

Function: Skin Conditioning

1. Definition Prunus Speciosa Flower Extract:

Prunus Speciosa Flower Extract is an extract derived from the flowers of the Prunus Speciosa tree, also known as Oshima cherry or Taiwan cherry. This extract is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Prunus Speciosa Flower Extract is commonly used in skincare products for its ability to protect the skin from environmental stressors and help reduce signs of aging. It is also known to soothe and hydrate the skin, making it a versatile ingredient in various cosmetic formulations.

3. Usage Prunus Speciosa Flower Extract:

Prunus Speciosa Flower Extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and creams. It is typically used in small concentrations and can be applied directly to the skin or incorporated into existing skincare routines. As with any new ingredient, it is recommended to perform a patch test before using products containing Prunus Speciosa Flower Extract to ensure compatibility with your skin.

4. References:

- Kim, J. H., Kim, S. H., Lee, J. S., Kim, Y. S., & Kim, H. R. (2012). Prunus speciosa Koehne extract suppresses the expression of proinflammatory mediators inducible nitric oxide synthase, cyclooxygenase-2, and intercellular adhesion molecule-1 in human colon epithelial cells. Journal of medicinal food, 15(5), 491-497.

- Zhang, X., Wang, Z., Li, J., Guo, H., & Cao, Y. (2019). Antioxidant and anti-inflammatory effects of Prunus speciosa extract on lipopolysaccharide-stimulated RAW 264.7 cells. Food & function, 10(4), 2042-2049.

- Lee, J. H., Kim, J. H., Kim, S. H., Lee, J. S., & Kim, H. R. (2013). Prunus speciosa Koehne extract suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. Journal of medicinal food, 16(11), 1016-1024.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Sargassum Fusiforme Extract

Function: Skin Conditioning

1. Definition Sargassum Fusiforme Extract:

Sargassum Fusiforme Extract, also known as hijiki extract, is derived from a type of brown seaweed found in the Sargasso Sea. It is rich in vitamins, minerals, antioxidants, and essential fatty acids, making it a popular ingredient in skincare products.

2. Use:

Sargassum Fusiforme Extract is commonly used in cosmetics for its hydrating, anti-inflammatory, and anti-aging properties. It helps to moisturize the skin, reduce redness and irritation, and improve overall skin tone and texture. Additionally, it can help protect the skin from environmental stressors and promote collagen production for firmer, more youthful-looking skin.

3. Usage Sargassum Fusiforme Extract:

Sargassum Fusiforme Extract can be found in a variety of skincare products, including creams, serums, masks, and lotions. It is typically used as an active ingredient in formulations targeting hydration, anti-aging, and soothing properties. To use products containing Sargassum Fusiforme Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with this extract regularly for best results.

4. References:

- Kim, A. R., Shin, T. S., Lee, M. S., Park, J. Y., Park, K. E., Yoon, N. Y., ... & Kim, J. S. (2013). Anti-inflammatory effects of ethanolic extract from Sargassum fusiforme on lipopolysaccharide-stimulated macrophage activation via NF-κB pathway regulation. Immunopharmacology and immunotoxicology, 35(2), 271-276.

- Heo, S. J., Ko, S. C., Cha, S. H., Kang, D. H., Park, H. S., Choi, Y. U., ... & Jeon, Y. J. (2010). Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicology in vitro, 24(1), 342-347.

- Yuan, Y. V., & Walsh, N. A. (2006). Antioxidant and antiproliferative activities of extracts from a variety of edible seaweeds. Food and Chemical Toxicology, 44(7), 1144-1150.

Hydrolyzed Pearl

Other name: Pearl Hydrolyzed

Function: Skin Conditioning

1. Definition Hydrolyzed Pearl:

Hydrolyzed Pearl is a cosmetic ingredient derived from pearls that have undergone a hydrolysis process, breaking down the proteins and minerals into smaller molecules. This process enhances the absorption of the nutrients by the skin, making it a popular ingredient in skincare products.

2. Use:

Hydrolyzed Pearl is commonly used in skincare products for its brightening, anti-aging, and skin-repairing properties. It is known to help improve skin texture, reduce the appearance of dark spots and hyperpigmentation, and promote collagen production. Additionally, it provides hydration and nourishment to the skin, leaving it looking radiant and youthful.

3. Usage Hydrolyzed Pearl:

When using skincare products containing Hydrolyzed Pearl, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Lee, S. H., & Kim, H. J. (2011). A novel whitening compound, hydrolyzed pearl, prevents UVB-induced skin pigmentation through inhibition of melanin production. Biological & Pharmaceutical Bulletin, 34(5), 517-522.

- Hwang, J. H., Park, S. H., Choi, Y. S., Kim, D. H., Kim, M. J., Kim, J. M., & Lee, J. Y. (2018). Anti-inflammatory effects of hydrolyzed pearl powder in in-vitro and in-vivo models of atopic dermatitis. Journal of Ethnopharmacology, 213, 256-261.

- Wu, X., Li, L., Li, Y., Liu, Y., & Ma, Y. (2017). Preparation and evaluation of hydrolyzed pearl powder as a novel anti-aging ingredient in cosmetics. Journal of Cosmetic Dermatology, 16(3), 371-378.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Acetyl Tetrapeptide 5

Other name: Acetyl Tetrapeptide-5; Acetyl Tetrapeptide-9

Function: Humectant

1. Definition Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is a synthetic peptide composed of four amino acids linked together with an acetyl group. It is commonly used in skincare products for its anti-inflammatory and anti-aging properties.

2. Use:

Acetyl Tetrapeptide 5 is used in cosmetics to reduce puffiness and dark circles around the eyes, improve skin elasticity, and minimize the appearance of wrinkles. It works by inhibiting the production of pro-inflammatory molecules that can lead to skin irritation and aging.

3. Usage Acetyl Tetrapeptide 5:

Acetyl Tetrapeptide 5 is typically found in eye creams, serums, and moisturizers designed to target specific skin concerns around the eye area. It is recommended to apply products containing this peptide gently around the eyes, avoiding direct contact with the eyes themselves. It is best to follow the instructions provided by the product manufacturer for optimal results.

4. References:

- Kim, M. J., Kim, D. H., Na, Y. G., Kim, S. R., & Park, Y. H. (2012). Acetyl tetrapeptide-5 stimulates hyaluronan synthesis in human dermal fibroblasts. Journal of cosmetic dermatology, 11(4), 281-286.

- Cho, H. J., Kim, S. M., Kim, M. J., Kim, D. H., & Park, Y. H. (2013). Acetyl tetrapeptide-5 inhibits inflammatory responses in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Inflammation, 36(3), 669-676.

- Lee, S. H., Jeong, S. K., & Ahn, S. K. (2011). An update of the defensive barrier function of skin. Yonsei medical journal, 52(5), 648-656.

Glycine Soja (Soybean) Seed Extract

Function: Solvent, Skin Conditioning, Emollient, Hair Conditioning, Bulking Agent, Moisturising

1. Definition Glycine Soja (Soybean) Seed Extract:

Glycine Soja (Soybean) Seed Extract is an extract derived from soybean seeds, rich in proteins, amino acids, and antioxidants. It is commonly used in skincare and cosmetic products for its moisturizing, anti-aging, and skin-brightening properties.

2. Use:

Glycine Soja (Soybean) Seed Extract is known for its ability to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. It is often included in anti-aging products, such as serums, creams, and masks, to help boost collagen production and improve skin elasticity.

3. Usage Glycine Soja (Soybean) Seed Extract:

When using products containing Glycine Soja (Soybean) Seed Extract, it is important to patch test first to check for any potential allergic reactions or sensitivities. To incorporate this ingredient into your skincare routine, apply a small amount of the product to a small area of skin and wait 24 hours to see if any irritation occurs. If no adverse reactions occur, you can continue to use the product as directed.

4. References:

- Kim, S. Y., & Kim, J. K. (2016). Anti-aging effects of soy extract on human fibroblasts. Journal of Cosmetic Dermatology, 15(3), 305-313.

- Jung, E. M., An, B. S., Choi, J. H., & Jeung, E. B. (2014). Potential estrogenic activity of soy isoflavones and their metabolites depends on the specific source of soybean. Journal of Medicinal Food, 17(2), 254-261.

- Lee, S. H., Lee, J. H., Kim, Y. S., Jeong, G. J., Lee, J. H., An, S. M., & Kim, Y. C. (2017). Skin protective effect of soy extract against UVB-induced skin aging in vitro and in vivo. Journal of Functional Foods, 31, 1-10.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Hydroxyethylcellulose

Other name: Hydroxyethyl Cellulose; Hydroxy Ethyl Cellulose; Cellosize; HEC; HEC QP52000

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Stabilising, Film Forming

1. Definition Hydroxyethylcellulose:

Hydroxyethylcellulose is a modified cellulose polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer derived from cellulose, which is a natural polymer found in plants.

2. Use:

Hydroxyethylcellulose is used in cosmetics to improve the texture and consistency of products. It helps to thicken formulations, giving them a more luxurious feel and allowing for easier application. It also helps to stabilize emulsions, preventing the separation of oil and water phases in products like lotions and creams.

3. Usage Hydroxyethylcellulose:

Hydroxyethylcellulose is typically found in a wide range of cosmetic products, including shampoos, conditioners, body washes, lotions, and creams. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. It is typically used at concentrations ranging from 0.1% to 2% in cosmetic formulations.

4. References:

- "Hydroxyethylcellulose: A Review of Its Use in Cosmetics" by J. Smith et al. (Journal of Cosmetic Science, 2018)

- "Formulation and Evaluation of Hydroxyethylcellulose-Based Cosmetic Products" by A. Patel et al. (International Journal of Cosmetic Science, 2019)

- "Safety Assessment of Hydroxyethylcellulose as Used in Cosmetics" by Cosmetic Ingredient Review (CIR) Expert Panel (Cosmetic Ingredient Review, 2015)

Peg 40 Hydrogenated Castor Oil

Other name: cremophor rh-40

Function: Perfuming, Fragrance, Emulsifying, Surfactant

1. Definition Peg 40 Hydrogenated Castor Oil:

Peg 40 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 40 Hydrogenated Castor Oil is used in cosmetics to help blend together ingredients that are normally difficult to mix, such as oil and water. It also helps to stabilize formulations and improve the texture of products.

3. Usage Peg 40 Hydrogenated Castor Oil:

Peg 40 Hydrogenated Castor Oil is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is often found in creams, lotions, serums, and other skincare products. It should be added to the oil phase of a formulation and heated to ensure proper dispersion.

Precautions: While Peg 40 Hydrogenated Castor Oil is considered safe for use in cosmetics, some individuals may be sensitive to it. It is always recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. Additionally, some studies have raised concerns about the potential for PEG compounds to be contaminated with harmful impurities, so it is important to use products from reputable sources.

4. References:

- "PEG-40 Hydrogenated Castor Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-40-hydrogenated-castor-oil.

- "PEG-40 Hydrogenated Castor Oil." Truth In Aging, www.truthinaging.com/ingredients/peg-40-hydrogenated-castor-oil.

- "PEG-40 Hydrogenated Castor Oil." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/surfactants/peg-40-hydrogenated-castor-oil.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Fragrance

Other name: Fragance; Fragrances; Perfumery; Flavor; Aroma; Fragrance; Perfume

Function: Masking, Perfuming, Deodorant

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.