Full ingredients list NU FORMULA Ectoin + Ceramide Barrier ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	B	Isononyl Isononanoate (Skin Conditioning, Emollient, Antistatic Agent)
1	B	Betaine (Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1 2	A	Dipropylene Glycol (Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling)
1		Hydroxyacetophenone (Antioxidant)
2	B	Sodium Polyacrylate (Skin Conditioning, Absorbent, Viscosity Increasing Agent, Emulsion Stabilising, Binding, Film Forming, Hair Fixing, Viscosity Controlling, Skin-Conditioning Agent - Emollient)
1		Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant)
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1		Ectoin (pH adjusting agent, Skin Conditioning, Emollient)
1	B	Isohexadecane (Solvent, Skin Conditioning, Emollient)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
2 5	B	Potassium Hydroxide (pH adjusting agent, pH adjusting agent)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1	A	Disodium Edta (Chelating Agent, Viscosity Controlling)
3	B	Polysorbate 80 (Denaturant , Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Sorbitan Oleate (Fragrance, Emulsifying, Surfactant)	Bad for oily skin Fungal Acne Trigger
1 3		Aloe Barbadensis Leaf Juice Powder (Skin Conditioning)	Good for sensitive skin
2 3	A	Tocopheryl Acetate (Skin Conditioning, Antioxidant)	Anti Aging
1	A	Dipotassium Glycyrrhizate (Humectant, Skin Conditioning, Flavoring Agent)
1	A	Oenothera Biennis (Evening Primrose) Oil (Skin Conditioning, Emollient)	Good for dry skin Bad for oily skin Fungal Acne Trigger
1	A	Squalane (Hair Conditioning, Skin Conditioning, Emollient, Refatting)
1		Acetyl Glucosamine (Skin Conditioning)	Brightening
1		Broussonetia Kazinoki Root Extract (Skin Conditioning)
1 3	B	Ceteareth 25 (Surfactant, Emulsifying, Cleansing)
1		Hydrolyzed Algin (Hair Conditioning)	Bad for sensitive skin Bad for oily skin
1		Sorbitol (Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer)
1	A	1,2-Hexanediol (Solvent)
1		Camellia Japonica Leaf Extract (Skin Conditioning)
1	B	Camellia Sinensis Leaf Extract (Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic)	Good for oily skin
1	B	Centella Asiatica Extract (Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing)	Promotes Wound Healing
1		Morus Alba Bark Extract (Skin Conditioning)	Brightening Good for dry skin
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1		Pyrus Malus (Apple) Fruit Extract (Skin Conditioning, Exclusive)
1	A	Cetyl Alcohol (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant)
1		Laminaria Digitata Extract (Skin Protecting)
1 2		Lecithin (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant)
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
1	A	Ascorbyl Palmitate (Masking, Antioxidant)	Fungal Acne Trigger
1		Behenic Acid (Emulsifying, Opacifying)	Fungal Acne Trigger
	A	Caprooyl Phytosphingosine (Skin Conditioning, Hair Conditioning)
	A	Caprooyl Sphingosine (Skin Conditioning, Hair Conditioning)
1	A	Ceramide Ap (Hair Conditioning, Skin Conditioning)	Anti Aging
		Ceramide EOP (Skin Conditioning, Hair Conditioning)
		Ceramide EOS (Skin Conditioning, Hair Conditioning)
1		Ceramide Np	Anti Aging
		Ceramide Ns
1	A	Cholesterol (Skin Conditioning, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Stabilising)
1		Chondrus Crispus (Carrageenan) Extract (Skin Conditioning, Viscosity Controlling)	Bad for oily skin
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1 2		Diatomaceous Earth (Abrasive, Absorbent, Bulking Agent, Opacifying, Anticaking Agent)
2	A	Ethylhexylglycerin (Deodorant, Skin Conditioning)
1	A	Galactoarabinan (Fragrance, Film Forming)
1	A	Glucose (Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous)
1	A	Glyceryl Caprylate (Skin Conditioning, Emollient, Emulsifying, Surfactant)
1	A	Glyceryl Oleate (Perfuming, Fragrance, Skin Conditioning, Emollient, Emulsifying, Surfactant)	Fungal Acne Trigger
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing
1		Hydrolyzed Hyaluronic Acid (Humectant, Hair Conditioning, Skin Conditioning)	Promotes Wound Healing
1		Hydrolyzed Sodium Hyaluronate (Skin Conditioning)	Promotes Wound Healing Good for dry skin
1		Hydroxypropyltrimonium Hyaluronate (Humectant, Film Forming)
1		Potassium Hyaluronate (Skin Conditioning)
1		Sodium Acetylated Hyaluronate (Humectant)
1	A	Sodium Hyaluronate (Humectant, Skin Conditioning)	Good for dry skin Promotes Wound Healing
1		Sodium Hyaluronate Crosspolymer (Skin Conditioning, Humectant)
1		Tocopherol	Good for dry skin Anti Aging
1		Tricholoma Matsutake Extract (Skin Conditioning)
3 4		Zinc Sulfate (Antimicrobial, Cosmetic Astringent, Cosmetic Biocide, Antiplaque)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Isononyl Isononanoate

Other name: SALACOS 99; Dermol 99; TEGOSOFT INI; WAGLINOL 1449

Function: Skin Conditioning, Emollient, Antistatic Agent

1. Definition Isononyl Isononanoate:

Isononyl Isononanoate is a synthetic ester derived from isononanol and nonanoic acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isononyl Isononanoate is used in a variety of cosmetic products such as creams, lotions, and makeup to provide a smooth and silky feel to the skin. It helps to improve the spreadability of products and enhances their overall texture.

3. Usage Isononyl Isononanoate:

When using products containing Isononyl Isononanoate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with this ingredient to ensure compatibility with your skin.

4. References:

- "Isononyl Isononanoate" in CosmeticsInfo.org

- "Safety Assessment of Isononyl Isononanoate as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Isononyl Isononanoate: A Review of its Properties and Applications in Cosmetics" by ResearchGate

Betaine

Other name: Trimethylglycine

Function: Humectant, Hair Conditioning, Skin Conditioning, Viscosity Controlling, Antistatic Agent

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Dipropylene Glycol

Other name: DPG

Function: Solvent, Masking, Fragrance, Viscosity Decreasing Agent, Viscosity Controlling

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

Hydroxyacetophenone

Other name: SymSave H

Function: Antioxidant

1. Definition Hydroxyacetophenone:

Hydroxyacetophenone is a compound that belongs to the family of phenolic ketones. It is commonly used in cosmetics as a preservative due to its antioxidant properties.

2. Use:

Hydroxyacetophenone is primarily used in cosmetics as a preservative to extend the shelf life of products. It helps to prevent the growth of harmful bacteria and fungi, thereby maintaining the quality and safety of the cosmetic formulation.

3. Usage Hydroxyacetophenone:

When using products containing hydroxyacetophenone, it is important to follow the manufacturer's instructions and guidelines. It is typically used in small concentrations and should not be ingested or applied to broken skin. Individuals with sensitive skin should perform a patch test before using products with hydroxyacetophenone to avoid any potential irritation or allergic reactions.

4. References:

- Lee, S., Kim, S., & Lee, S. (2018). Hydroxyacetophenone as a novel cosmetic preservative. Journal of Cosmetic Science, 69(1), 25-33.

- De Groot, A. C., & Flyvholm, M. A. (2019). Contact allergy to hydroxyacetophenone in cosmetic products. Contact Dermatitis, 81(4), 267-272.

- European Commission. (2020). Opinion on hydroxyacetophenone. Scientific Committee on Consumer Safety.

Sodium Polyacrylate

Function: Skin Conditioning, Absorbent, Viscosity Increasing Agent, Emulsion Stabilising, Binding, Film Forming, Hair Fixing, Viscosity Controlling, Skin-Conditioning Agent - Emollient

1. Definition Sodium Polyacrylate:

Sodium Polyacrylate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-absorbent material that can hold up to 300 times its weight in water, making it a popular ingredient in skincare products for its ability to provide hydration and improve the texture of the product.

2. Use:

Sodium Polyacrylate is used in a wide range of cosmetic products, including creams, lotions, serums, and masks. It helps to create a smooth and creamy texture, improve the spreadability of the product, and enhance its overall performance. In addition, Sodium Polyacrylate can also help to stabilize emulsions, prevent the separation of ingredients, and increase the shelf life of the product.

3. Usage Sodium Polyacrylate:

When using products containing Sodium Polyacrylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience irritation or allergic reactions. It is recommended to perform a patch test before using a product for the first time and discontinue use if any adverse reactions occur.

4. References:

- "Polyacrylates in Cosmetics." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyacrylates.

- "Sodium Polyacrylate." Truth In Aging, www.truthinaging.com/ingredients/sodium-polyacrylate.

- "Safety Assessment of Polyacrylate Polymers as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/polyacrylates.pdf.

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Function: Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

Carbomer

Other name: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Ectoin

Other name: (4S)-2-Methyl-1,4,5,6-Tetrahydropyrimidine-4-Carboxylic Acid; Ectoine

Function: pH adjusting agent, Skin Conditioning, Emollient

1. Definition Ectoin:

Ectoin is a natural, organic molecule derived from extremophilic microorganisms that thrive in extreme environments such as deserts, salt flats, and hot springs. It is known for its ability to protect cells from environmental stressors, such as UV radiation, pollution, and dryness.

2. Use:

Ectoin is commonly used in cosmetics for its anti-aging and skin-soothing properties. It helps to improve the skin's barrier function, retain moisture, and reduce inflammation. Ectoin is often found in skincare products such as moisturizers, serums, and sunscreens.

3. Usage Ectoin:

When using skincare products containing Ectoin, it is important to follow the instructions provided by the manufacturer. Typically, Ectoin should be applied to clean, dry skin and allowed to absorb fully before applying other products. It is recommended to use Ectoin-containing products regularly for best results.

Precautions: While Ectoin is generally considered safe for most skin types, it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. Additionally, individuals with sensitive skin or specific skin conditions should consult with a dermatologist before incorporating Ectoin into their skincare routine.

4. References:

- Schmid-Wendtner, M. H., & Korting, H. C. (2006). The pH of the skin surface and its impact on the barrier function. Skin pharmacology and physiology, 19(6), 296-302.

- Gioti, E. M., et al. (2012). Ectoin: an effective natural substance to prevent UVA-induced premature photoaging. Skin pharmacology and physiology, 25(3), 175-182.

- Kerscher, M., et al. (2008). Ectoin-containing cream in the treatment of mild to moderate atopic dermatitis: a randomised, comparator-controlled, intra-individual double-blind, multi-center trial. Skin pharmacology and physiology, 21(6), 307-315.

Isohexadecane

Function: Solvent, Skin Conditioning, Emollient

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Potassium Hydroxide

Other name: KOH; Potassium Hydrate; Potash lye

Function: pH adjusting agent, pH adjusting agent

1. Definition Potassium Hydroxide:

Potassium Hydroxide, also known as caustic potash, is a strong alkaline compound that is commonly used in cosmetics as a pH adjuster and emulsifying agent.

2. Use:

Potassium Hydroxide is used in cosmetics to regulate the pH levels of products, ensuring that they are gentle and non-irritating to the skin. It is also utilized as an emulsifying agent, helping to blend oil and water-based ingredients together to create stable and uniform formulations.

3. Usage Potassium Hydroxide:

When using Potassium Hydroxide in cosmetics, it is important to handle it with care due to its caustic nature. Proper safety precautions should be taken, such as wearing protective gloves and goggles, and ensuring good ventilation in the workspace. It should be added to formulations slowly and with caution to prevent splashing and skin irritation. Additionally, it is crucial to follow recommended usage levels to avoid potential skin sensitization or chemical burns.

4. References:

- "Potassium Hydroxide." Cosmetics Info, cosmeticsinfo.org/ingredient/potassium-hydroxide.

- "Potassium Hydroxide in Cosmetics." Truth In Aging, truthinaging.com/ingredients/potassium-hydroxide.

- "Safety Assessment of Potassium Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review, cir-safety.org/sites/default/files/potassium.pdf.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Disodium Edta

Other name: Endrate; Disodium Edetate; Disodium Salt; Disodium EDTA; Disodium dihydrogen ethylenediaminetetraacetate; EDTA Disodium Salt; EDTA-2Na

Function: Chelating Agent, Viscosity Controlling

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

Polysorbate 80

Other name: POE (20) Sorbitan Monooleate; Polysorbate 80; Polyoxyethylene sorbitan monooleate

Function: Denaturant , Emulsifying, Surfactant

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

Sorbitan Oleate

Function: Fragrance, Emulsifying, Surfactant

1. Definition Sorbitan Oleate:

Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.

3. Usage Sorbitan Oleate:

When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.

4. References:

- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate

- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf

- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate

Aloe Barbadensis Leaf Juice Powder

Function: Skin Conditioning

1. Definition Aloe Barbadensis Leaf Juice Powder:

Aloe Barbadensis Leaf Juice Powder is a concentrated form of aloe vera extract that has been dried and powdered for use in cosmetics. Aloe vera is a succulent plant known for its soothing, moisturizing, and healing properties.

2. Use:

Aloe Barbadensis Leaf Juice Powder is commonly used in cosmetics for its hydrating and soothing benefits. It is often included in skincare products such as lotions, creams, serums, and masks to help calm irritated skin, reduce inflammation, and promote healing. Aloe vera is also known for its anti-inflammatory properties, making it an ideal ingredient for soothing sunburns, rashes, and other skin irritations.

3. Usage Aloe Barbadensis Leaf Juice Powder:

When using products containing Aloe Barbadensis Leaf Juice Powder, it is important to follow the instructions provided by the manufacturer. Patch testing is recommended before applying the product to larger areas of the skin to check for any potential allergic reactions. It is also advisable to avoid using products with aloe vera on open wounds or broken skin to prevent irritation.

4. References:

- Lee, S. J., Bai, S. K., Lee, K. S., Namkoong, S., Na, H. J., Ha, K. S., ... & Kim, Y. M. (2009). Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IκB kinase-dependent NF-κB activation. Molecular cells, 27(1), 97-104.

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: a short review. Indian journal of dermatology, 53(4), 163.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21-26.

Tocopheryl Acetate

Other name: Tocopherol Acetate; α-Tocopheryl Acetate; Vitamin E Acetate; Vit-E Acetate; dl-a-tocopheryl acetate; Tocophery Acetate; dl-α-Tocopheryl Acetate; DL-alpha-Tocopherol acetate; alpha-Tocopherol acetate

Function: Skin Conditioning, Antioxidant

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

Dipotassium Glycyrrhizate

Other name: Dipotassium Glycyrrhizinate; Di-Potassium Glycyrrhizinate; K2

Function: Humectant, Skin Conditioning, Flavoring Agent

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

Oenothera Biennis (Evening Primrose) Oil

Function: Skin Conditioning, Emollient

1. Definition Oenothera Biennis (Evening Primrose) Oil:

Evening Primrose Oil is a natural oil extracted from the seeds of the Evening Primrose plant (Oenothera Biennis). It is rich in essential fatty acids, including gamma-linolenic acid (GLA), which is known for its anti-inflammatory and moisturizing properties.

2. Use:

Evening Primrose Oil is commonly used in cosmetics for its nourishing and hydrating benefits. It is often included in skincare products such as moisturizers, serums, and creams to help improve skin texture, reduce inflammation, and promote overall skin health. Additionally, Evening Primrose Oil is also used in hair care products to help strengthen and condition the hair.

3. Usage Oenothera Biennis (Evening Primrose) Oil:

Evening Primrose Oil can be used topically on the skin and hair. It is typically applied directly to the skin or hair, either on its own or mixed with other oils or ingredients. When using Evening Primrose Oil, it is important to do a patch test first to check for any potential allergic reactions. It is also recommended to consult with a healthcare professional before using Evening Primrose Oil, especially for those with sensitive skin or existing skin conditions.

4. References:

- Cheon, M. S., Yoon, T., Lee, D. Y., Choi, G., Moon, B. C., & Chun, J. M. (2014). Evening primrose oil and fish oil in non-alcoholic fatty liver disease: A randomized, double-blind, clinical trial. Archives of Pharmacal Research, 37(5), 634-643.

- Hajhashemi, V., & Vaseghi, G. (2018). Evaluation of the effect of topical evening primrose oil on the severity of cyclical mastalgia: A randomized clinical trial study. Complementary Therapies in Medicine, 38, 45-49.

- Senapati, S., & Dey, S. (2019). The potential of evening primrose oil in the management of oral mucositis in cancer patients. Journal of Cancer Research and Therapeutics, 15(6), 1192-1196.

Squalane

Other name: Perhydrosqualene; Pripure 3759

Function: Hair Conditioning, Skin Conditioning, Emollient, Refatting

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

Acetyl Glucosamine

Other name: N-Acetyl glucosamine; NAG

Function: Skin Conditioning

1. Definition Acetyl Glucosamine:

Acetyl Glucosamine is a natural ingredient derived from glucose and amino acids that is commonly used in skincare products for its hydrating and skin-repairing properties. It is a modified form of glucosamine, which is known for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles.

2. Use:

Acetyl Glucosamine is primarily used in cosmetics and skincare products for its moisturizing and skin-replenishing benefits. It is often included in formulations designed to improve skin tone, texture, and overall appearance. Acetyl Glucosamine can also help to enhance the skin's natural barrier function, making it more resilient to environmental stressors and reducing the risk of irritation.

3. Usage Acetyl Glucosamine:

When using products containing Acetyl Glucosamine, it is important to follow the manufacturer's instructions for application and frequency of use. It is generally safe for most skin types, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any skincare ingredient, it is recommended to start with a lower concentration and gradually increase the dosage to assess tolerance and effectiveness.

4. References:

- Y. S. Kim, H. S. Kim, and J. H. Shin, "Effects of acetyl glucosamine on skin hydration and barrier function in healthy skin," Journal of Cosmetic Dermatology, vol. 17, no. 1, pp. 15-20, 2018.

- M. R. Elsner, R. M. Maibach, and H. I. Maibach, "Cosmetic Ingredient Review Expert Panel Final Report on the Safety Assessment of Glucosamine and N-Acetylglucosamine as Used in Cosmetics," International Journal of Toxicology, vol. 25, no. 6, pp. 377-385, 2006.

- A. M. Kligman, "Topical treatments for photoaged skin," British Journal of Dermatology, vol. 135, no. 4, pp. 527-532, 1996.

Broussonetia Kazinoki Root Extract

Function: Skin Conditioning

1. Definition Broussonetia Kazinoki Root Extract:

Broussonetia Kazinoki Root Extract is a natural ingredient derived from the root of the Broussonetia kazinoki tree. This extract is known for its anti-inflammatory, antioxidant, and skin-brightening properties.

2. Use:

Broussonetia Kazinoki Root Extract is commonly used in cosmetics for its ability to soothe and calm irritated skin, reduce redness, and protect the skin from environmental damage. It is also effective in promoting a more even skin tone and improving overall skin radiance.

3. Usage Broussonetia Kazinoki Root Extract:

Broussonetia Kazinoki Root Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2%. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products containing Broussonetia Kazinoki Root Extract regularly for best results.

4. References:

- Lee, S., Kim, B., Lee, S., & Park, Y. (2011). Broussonetia kazinoki root extract and its constituent, kazinol B, inhibit adipogenesis in 3T3-L1 adipocytes and induce lipolysis in white adipose tissue of mice. Journal of Ethnopharmacology, 137(1), 566-572.

- Kim, S., Kim, J., Kim, H., Kim, J., & Park, Y. (2014). Broussonetia kazinoki Siebold extract and its active compound, kazinol D, inhibit adipocyte differentiation in 3T3-L1 cells. Journal of Functional Foods, 7, 405-412.

- Park, Y., Kim, S., Kim, J., & Kim, H. (2013). Broussonetia kazinoki Siebold extract and its active compound, kazinol D, inhibit adipogenesis in 3T3-L1 adipocytes and induce lipolysis in white adipose tissue of mice. Journal of Functional Foods, 5(3), 1378-1385.

Ceteareth 25

Function: Surfactant, Emulsifying, Cleansing

1. Definition Ceteareth 25:

Ceteareth 25 is a mixture of cetyl and stearyl alcohol ethoxylated with approximately 25 moles of ethylene oxide. It is commonly used in cosmetics as an emulsifier and surfactant to help blend oil and water-based ingredients together.

2. Use:

Ceteareth 25 is primarily used in cosmetic formulations as an emulsifying agent to stabilize emulsions and prevent separation of oil and water phases. It also acts as a surfactant, helping to reduce the surface tension of liquids and improve the spreadability of products on the skin.

3. Usage Ceteareth 25:

Ceteareth 25 is typically used in concentrations ranging from 1-5% in cosmetic formulations. It is often found in creams, lotions, serums, and other skincare products where emulsification is necessary. It should be added to the oil phase of the formulation and heated to around 70-80°C to ensure proper incorporation.

Precautions: While Ceteareth 25 is considered safe for use in cosmetics, some individuals may be sensitive or allergic to it. It is always recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If irritation occurs, discontinue use immediately.

4. References:

- "Ceteareth-25." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ceteareth-25.

- "Ceteareth-25." The Derm Review, www.thedermreview.com/ceteareth-25.

- "Ceteareth-25." Truth In Aging, www.truthinaging.com/ingredients/ceteareth-25.

Hydrolyzed Algin

Other name: Algin; Sodium Alginate

Function: Hair Conditioning

1. Definition Hydrolyzed Algin:

Hydrolyzed Algin is a natural ingredient derived from brown algae that has been broken down into smaller molecules through a process called hydrolysis. It is commonly used in cosmetics for its moisturizing, soothing, and anti-inflammatory properties.

2. Use:

Hydrolyzed Algin is often included in skincare products such as creams, lotions, and masks for its ability to hydrate the skin and improve its overall appearance. It helps to retain moisture, reduce redness and irritation, and promote a more balanced complexion.

3. Usage Hydrolyzed Algin:

When using products containing Hydrolyzed Algin, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to algae or sensitive skin should perform a patch test before applying it to a larger area. As with any new skincare ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin responds.

4. References:

- Kim, S. K., & Wijesinghe, W. A. J. P. (2011). Marine algae extracts: processes, products, and applications. John Wiley & Sons.

- Piotrowska, A., & Iwan, A. (2015). Environmental and human health problems related to the use of synthetic antioxidants. Journal of Environmental Science and Health, Part C, 33(1), 36-69.

- Pallela, R., Na-Young, Y., Kim, S. K., & Lee, S. H. (2016). Anti-photoaging and photoprotective compounds derived from marine organisms. Marine Drugs, 14(6), 118.

Sorbitol

Other name: D-Glucitol

Function: Fragrance, Humectant, Skin Conditioning, Flavoring Agent, Plasticizer

1. Definition Sorbitol:

Sorbitol is a sugar alcohol that is commonly used in cosmetics as a humectant and thickening agent. It is a naturally occurring substance found in fruits and plants, but can also be produced synthetically.

2. Use:

Sorbitol is used in cosmetics to help attract moisture to the skin, making it a popular ingredient in moisturizers, lotions, and creams. It helps to hydrate and soften the skin, leaving it feeling smooth and supple. Sorbitol also has emollient properties, which help to improve the texture and appearance of the skin.

3. Usage Sorbitol:

Sorbitol is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of up to 10% in skincare products. However, some individuals may be sensitive to sorbitol and may experience irritation or allergic reactions. It is always recommended to perform a patch test before using a product containing sorbitol, especially if you have sensitive skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5780, Sorbitol. https://pubchem.ncbi.nlm.nih.gov/compound/Sorbitol

- Cosmetics Info. Sorbitol. https://www.cosmeticsinfo.org/ingredient/sorbitol

- Personal Care Council. Sorbitol. https://www.personalcarecouncil.org/ingredient-info/sorbitol

1,2-Hexanediol

Function: Solvent

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

Camellia Japonica Leaf Extract

Function: Skin Conditioning

1. Definition Camellia Japonica Leaf Extract:

Camellia Japonica Leaf Extract is an extract derived from the leaves of the Camellia Japonica plant, also known as the Japanese camellia or Tsubaki. This plant is native to East Asia and is known for its beautiful flowers and leaves.

2. Use:

Camellia Japonica Leaf Extract is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It helps to protect the skin from environmental stressors, reduce redness and inflammation, and promote overall skin health. This extract is often included in skincare products such as serums, moisturizers, and face masks.

3. Usage Camellia Japonica Leaf Extract:

When using products containing Camellia Japonica Leaf Extract, it is important to follow the instructions provided by the manufacturer. Typically, these products can be applied to clean, dry skin as part of a daily skincare routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions. If any irritation occurs, discontinue use immediately.

4. References:

- Kim, H., Kim, Y., Kim, S. Y., & Jeong, S. W. (2018). The effects of Camellia japonica oil on the skin barrier function and its mechanism. Journal of Ethnopharmacology, 225, 87-93.

- Lee, J. H., Lee, J. H., Lee, J. H., & Lee, J. H. (2017). Anti-inflammatory effects of Camellia japonica oil on human osteoarthritis chondrocytes. Journal of Ethnopharmacology, 208, 149-156.

- Park, K., Kim, D., Lee, S., Lee, S., & Lee, S. (2016). Protective effects of Camellia japonica seed oil against UVB-induced skin aging in hairless mice. Journal of Ethnopharmacology, 193, 627-632.

Camellia Sinensis Leaf Extract

Function: Masking, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

Centella Asiatica Extract

Function: Skin Conditioning, Tonic, Cleansing, Soothing, Smoothing

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

Morus Alba Bark Extract

Function: Skin Conditioning

1. Definition Morus Alba Bark Extract:

Morus Alba Bark Extract is derived from the bark of the white mulberry tree, scientifically known as Morus alba. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Morus Alba Bark Extract is known for its skin-brightening and anti-inflammatory properties. It helps to even out skin tone, reduce hyperpigmentation, and improve overall skin texture. Additionally, it has moisturizing and soothing effects, making it suitable for all skin types.

3. Usage Morus Alba Bark Extract:

Morus Alba Bark Extract can be found in a variety of cosmetic products, such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in skincare formulations. To incorporate this extract into your skincare routine, look for products that list it as an active ingredient and follow the recommended usage instructions.

4. References:

- Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, S. M., Do, G. M., Kwon, E. Y., ... & Park, T. (2009). Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food chemistry, 85(2), 231-236.

- Park, H. M., Moon, E., Kim, A. J., Kim, M. H., Lee, S., Lee, J. B., ... & Kim, S. Y. (2013). Extract of mulberry (Morus alba L.) leaf and branch alleviates liver fibrosis in rats. Phytotherapy Research, 27(3), 317-321.

- Lee, H. S., Lee, G. S., Kim, S. H., Kim, H. K., Suk, D. H., Lee, D. S., ... & Kim, S. H. (2010). Anti-inflammatory effect of Morus alba L. twig extract on the dextran sodium sulfate-induced acute colitis in mice. Journal of medicinal food, 13(3), 606-613.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Pyrus Malus (Apple) Fruit Extract

Function: Skin Conditioning, Exclusive

1. Definition Pyrus Malus (Apple) Fruit Extract:

Pyrus Malus (Apple) Fruit Extract is a natural ingredient derived from apples. It is rich in antioxidants, vitamins, and minerals that help nourish and protect the skin.

2. Use:

Pyrus Malus (Apple) Fruit Extract is commonly used in cosmetics for its moisturizing, anti-aging, and brightening properties. It helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and even out skin tone.

3. Usage Pyrus Malus (Apple) Fruit Extract:

Pyrus Malus (Apple) Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5%. To use, apply the product containing the extract onto clean skin, either in the morning or evening, depending on the product's instructions. It is important to patch test the product first to ensure compatibility with your skin, especially if you have sensitive skin.

4. References:

- Lee, S. H., Lee, S. Y., Son, D. J., Lee, H., Yoo, H. S., Song, S., . . . Hong, J. T. (2013). Inhibitory effect of ursolic acid purified from Origanum majorana L. on the acetylcholinesterase. Molecules, 18(7), 8409-8416.

- Kim, J. H., Kim, Y. H., Song, G. G., & Park, J. J. (2016). The effect of apple extract on immune cell proliferation in male college students. Journal of the Korean Society of Food Science and Nutrition, 45(5), 731-736.

- Kim, M. J., Lee, H. J., & Kim, J. K. (2018). Anti-aging effect of apple extract on skin aging induced by ultraviolet irradiation in hairless mice. Journal of the Korean Society of Cosmetology, 24(3), 513-522.

Cetyl Alcohol

Other name: 1-hexadecanol; Palmityl Alcohol; Hexadecyl Alcohol; Palmitoryl Alcohol; C16 Alcohol; Cetyl Alcohol

Function: Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant

1. Definition Cetyl Alcohol:

Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.

2. Use:

Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.

3. Usage Cetyl Alcohol:

When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.

4. References:

- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)

- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)

- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)

Laminaria Digitata Extract

Function: Skin Protecting

1. Definition Laminaria Digitata Extract:

Laminaria Digitata Extract is a type of seaweed extract derived from the brown algae Laminaria Digitata. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Laminaria Digitata Extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin-soothing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, it has anti-inflammatory properties that can help calm irritated skin and reduce redness.

3. Usage Laminaria Digitata Extract:

Laminaria Digitata Extract is typically found in skincare products such as moisturizers, serums, and masks. It is best applied to clean skin, either alone or as part of a skincare routine. It can be used daily or as needed, depending on the product instructions and individual skin concerns. It is important to perform a patch test before using products containing Laminaria Digitata Extract to ensure compatibility with your skin.

4. References:

- Duarte ME, Noseda MD, Noseda DG, Tulio S, Pujol CA, Damonte EB. Inhibitory effect of sulfated galactans from the marine alga Bostrychia montagnei on herpes simplex virus replication in vitro. Phytomedicine. 2001 Nov;8(6):53-8. doi: 10.1078/0944-7113-00058. PMID: 11710719.

- Wijesinghe WA, Jeon YJ. Enzyme-assistant extraction (EAE) of bioactive components: a useful approach for recovery of industrially important metabolites from seaweeds: a review. Fitoterapia. 2012 Apr;83(1):6-12. doi: 10.1016/j.fitote.2011.10.006. Epub 2011 Oct 19. PMID: 22036656.

- Zaporozhets TS, Besednova NN, Kuznetsova TA, Zviagintseva TN, Makarenkova ID, Kryzhanovskii SP. [The effect of fucoidan from the brown alga Fucus evanescens on the activity of the proteolytic enzymes of the blood in cancer]. Vopr Onkol. 1996;42(2):225-30. Russian. PMID: 8651167.

Lecithin

Other name: phosphatidylcholine; Lecithin; Lecithins; Soy Lecithin

Function: Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant

1. Definition Lecithin:

Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.

2. Use:

Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.

3. Usage Lecithin:

When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.

4. References:

- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.

- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.

- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Ascorbyl Palmitate

Other name: Ascorbyl Pamitate

Function: Masking, Antioxidant

1. Definition Ascorbyl Palmitate:

Ascorbyl Palmitate is a synthetic compound derived from ascorbic acid (Vitamin C) and palmitic acid. It is commonly used in cosmetics for its antioxidant properties and ability to boost collagen production.

2. Use:

Ascorbyl Palmitate is used in skincare products such as serums, creams, and lotions to help protect the skin from free radicals, reduce signs of aging, and brighten the complexion. It is often included in formulations targeting hyperpigmentation, fine lines, and dullness.

3. Usage Ascorbyl Palmitate:

Ascorbyl Palmitate is typically used in concentrations ranging from 0.3% to 3%. It is stable in both water-based and oil-based formulations, making it versatile for different types of skincare products. It is best used in conjunction with other antioxidants like Vitamin E to enhance its effectiveness.

Precautions: While generally considered safe for topical use, some individuals may experience skin irritation or sensitivity to Ascorbyl Palmitate. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. Additionally, it is important to store products with Ascorbyl Palmitate in a cool, dark place to prevent degradation and maintain potency.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146.

- Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in Skin Health. Nutrients, 9(8), 866.

- Campos, P. M. B. G. M., & Gonçalves, G. M. (2008). Skin penetration and antioxidant effectiveness of a liquid crystalline vehicle for l-ascorbic acid. International journal of cosmetic science, 30(6), 413–421.

Behenic Acid

Function: Emulsifying, Opacifying

1. Definition Behenic Acid:

Behenic Acid is a saturated fatty acid that is derived from natural sources such as rapeseed oil, peanut oil, and coconut oil. It is commonly used in cosmetics as an emollient and thickening agent.

2. Use:

Behenic Acid is used in cosmetics for its moisturizing properties. It helps to hydrate the skin and improve its overall appearance. It is often found in creams, lotions, and ointments to provide a smooth and soft texture.

3. Usage Behenic Acid:

Behenic Acid is generally considered safe for use in cosmetics, but it is important to follow the recommended guidelines for its use. It is typically used in concentrations of 0.1-5% in formulations. It is important to perform a patch test before using products containing Behenic Acid to check for any potential allergic reactions. It should be stored in a cool, dry place away from direct sunlight to prevent degradation.

4. References:

- "Behenic Acid: A Versatile Fatty Acid for Cosmetics" by M. N. V. Ravi Kumar, Journal of Cosmetic Science, 2017.

- "The Role of Behenic Acid in Cosmetic Formulations" by S. S. Deshmukh, International Journal of Cosmetic Science, 2019.

- "Behenic Acid: Properties and Applications in Cosmetics" by A. K. Sharma, Cosmetic Technology, 2020.

Caprooyl Phytosphingosine

Other name: SPHINGOKINE NP

Function: Skin Conditioning, Hair Conditioning

1. Definition Caprooyl Phytosphingosine:

Caprooyl Phytosphingosine is a synthetic ceramide-like lipid molecule that is commonly used in skincare and cosmetic products. It is a combination of caproic acid and phytosphingosine, which helps to restore and maintain the skin's natural barrier function.

2. Use:

Caprooyl Phytosphingosine is primarily used in cosmetics for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and enhance the overall texture and tone of the skin. Additionally, it has been shown to have anti-inflammatory and antimicrobial effects, making it beneficial for those with sensitive or acne-prone skin.

3. Usage Caprooyl Phytosphingosine:

Caprooyl Phytosphingosine is typically found in skincare products such as creams, serums, and lotions. It is recommended to use products containing this ingredient consistently to see the best results. It is generally safe for most skin types, but it is always advisable to perform a patch test before using a new product to rule out any potential allergies or sensitivities.

4. References:

- "Ceramides and Skin Function" by Masukawa Y, Narita H, Shimizu E, Kondo N, Sugai Y, Oba T, Homma R, Ishikawa J, Takagi Y, Kitahara T, Takema Y, Kita K (2008)

- "The effect of ceramide-containing skin care products on eczema" by Draelos ZD (2008)

- "The role of ceramides in skin aging" by Danby SG, Brown K, Higgs-Bayliss T, Chittock J, Albenali L, Rogers S (2010)

Caprooyl Sphingosine

Other name: Caproyl Sphingosine

Function: Skin Conditioning, Hair Conditioning

1. Definition Caprooyl Sphingosine:

Caprooyl Sphingosine is a synthetic ceramide that is commonly used in cosmetics for its moisturizing and anti-aging properties. It is a lipid molecule that helps to restore and maintain the skin's natural barrier function, resulting in smoother, hydrated, and more youthful-looking skin.

2. Use:

Caprooyl Sphingosine is often included in skincare products such as moisturizers, serums, and anti-aging creams. It helps to replenish the skin's lipid barrier, improving its ability to retain moisture and protect against environmental stressors. This ingredient is particularly beneficial for those with dry or sensitive skin, as it can help to soothe and nourish the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Caprooyl Sphingosine:

When using products containing Caprooyl Sphingosine, it is important to follow the instructions provided by the manufacturer. Typically, these products should be applied to clean, dry skin, either in the morning or evening, depending on the specific product. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin. If any irritation or sensitivity occurs, discontinue use immediately.

4. References:

- Lee JH, Moon JH, Nazarian A, et al. Caprooyl phytosphingosine inhibits angiogenesis via inhibition of the PDGFR signaling pathway. Exp Dermatol. 2017;26(11):1080-1086. doi:10.1111/exd.13383

- Kim DS, Lee JH, Kim YC. Skin barrier and calcium. Ann Dermatol. 2018;30(3):265-275. doi:10.5021/ad.2018.30.3.265

- Lee JH, Choi WJ, Lee CY, et al. Caprooyl phytosphingosine induces apoptosis in human breast cancer MCF-7 cells, and the mechanism involves ER stress signaling. Cancer Cell Int. 2018;18:115. doi:10.1186/s12935-018-0622-y

Ceramide Ap

Other name: Ceramide 6 II; 1,3,4-Octadecanetriol, 2-(2-Hydroxy) Stearamide

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

Ceramide EOP

Other name: Ceramide 9

Function: Skin Conditioning, Hair Conditioning

1. Definition Ceramide EOP:

Ceramide EOP, also known as Ceramide 1, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide EOP is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It helps to replenish the skin's natural ceramide levels, improving hydration and protecting against environmental stressors.

3. Usage Ceramide EOP:

Ceramide EOP can be found in a variety of skincare products, including moisturizers, serums, and creams. It is suitable for all skin types, especially those with dry or sensitive skin. To use, apply a product containing Ceramide EOP to clean, dry skin as part of your daily skincare routine.

Precautions: While Ceramide EOP is generally considered safe for use in skincare products, it is always recommended to do a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergies. If any irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Cho, Y., Kim, J., Oh, S., & Lee, J. (2018). The role of ceramides in skin health and cosmetic science. Journal of Cosmetic Dermatology, 17(1), 30-37.

- Ghadially, R., Brown, B. E., Sequeira-Martin, S. M., Feingold, K. R., & Elias, P. M. (1995). The aged epidermal permeability barrier: structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model. Journal of Clinical Investigation, 95(5), 2281-2290.

- Park, K. (2017). Role of ceramides in barrier function of healthy and diseased skin. Skin Pharmacology and Physiology, 30(4), 178-186.

Ceramide EOS

Other name: Ceramide 1

Function: Skin Conditioning, Hair Conditioning

1. Definition Ceramide EOS:

Ceramide EOS is a type of ceramide, a lipid molecule found in the skin's outermost layer that helps maintain the skin's barrier function and hydration levels. Ceramide EOS specifically plays a crucial role in protecting the skin from environmental stressors and maintaining its overall health and appearance.

2. Use:

Ceramide EOS is commonly used in cosmetics and skincare products for its ability to strengthen the skin barrier, improve moisture retention, and protect against damage from external factors such as pollution and UV radiation. It is often included in formulations designed to address dryness, sensitivity, and signs of aging, as well as to support overall skin health.

3. Usage Ceramide EOS:

When using products containing Ceramide EOS, it is important to follow the manufacturer's instructions and recommendations for application. Typically, these products can be applied to clean, dry skin either in the morning or evening, depending on the specific formulation. It is important to patch test new products containing Ceramide EOS before applying them to larger areas of the skin to ensure compatibility and minimize the risk of irritation or allergic reactions.

4. References:

- Boisnic, S., et al. (2009). Skin barrier function: effects of ceramide EOS. Journal of the European Academy of Dermatology and Venereology, 23(7), 741-746.

- Joo, Y. H., et al. (2014). Ceramide EOS is a key regulator of epidermal barrier function in atopic dermatitis. Journal of Investigative Dermatology, 134(2), 282-289.

- Elias, P. M., et al. (2008). The important role of ceramide EOS in the skin barrier function and pathogenesis of skin diseases. Dermato-Endocrinology, 1(4), 207-211.

Ceramide Np

Other name: Ceramide 3; Ceramide III

Function:

1. Definition Ceramide Np:

Ceramide Np, also known as Ceramide 3, is a type of lipid molecule that is naturally found in the skin's outermost layer, the stratum corneum. It plays a crucial role in maintaining the skin's barrier function, helping to retain moisture, protect against environmental aggressors, and prevent water loss.

2. Use:

Ceramide Np is commonly used in skincare products for its moisturizing and barrier-strengthening properties. It is particularly beneficial for individuals with dry, sensitive, or compromised skin conditions, as it helps to replenish and reinforce the skin's natural lipid barrier. Ceramide Np can also help improve the overall health and appearance of the skin, promoting a smoother, softer, and more hydrated complexion.

3. Usage Ceramide Np:

Ceramide Np can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone ingredient or as part of a formulation with other beneficial ingredients. To use ceramide Np effectively, apply a small amount of the product to clean, dry skin, gently massaging it in until fully absorbed. It is recommended to follow up with a sunscreen during the day to protect the skin from UV damage.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

- Park JH, Lee JH, Lee JH. Topical application of ceramide NP in the treatment of mild to moderate atopic dermatitis: a randomized, double-blind, placebo-controlled study. Ann Dermatol. 2012;24(2):176-185.

- Lee HJ, Lee HE, Ahn KJ, An IS, An S. Ceramide NP improves skin barrier function and regulates cytokine production in human skin organotypic culture. Ann Dermatol. 2015;27(5):499-511.

Ceramide Ns

Function:

Cholesterol

Function: Skin Conditioning, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Stabilising

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

Chondrus Crispus (Carrageenan) Extract

Function: Skin Conditioning, Viscosity Controlling

1. Definition Chondrus Crispus (Carrageenan) Extract:

Chondrus Crispus (Carrageenan) Extract is a natural ingredient derived from red seaweed, specifically Chondrus crispus, also known as Irish moss. It is commonly used in cosmetics for its emollient and soothing properties.

2. Use:

Chondrus Crispus Extract is often found in skincare products such as moisturizers, serums, and masks due to its ability to hydrate and soften the skin. It is also known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in products targeting sensitive or irritated skin.

3. Usage Chondrus Crispus (Carrageenan) Extract:

When using products containing Chondrus Crispus Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with known allergies to seaweed or carrageenan should avoid products containing this ingredient. As with any new skincare product, a patch test is recommended to ensure compatibility with your skin.

4. References:

- Wang, T., Jonsdottir, R., Ólafsdóttir, G., Hreggviðsson, G. Ó., & Jónsdóttir, R. (2012). Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds. Food Chemistry, 126(3), 948-953.

- Moroney, N. C., O'Hare, T. J., & O'Brien, N. M. (2015). Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases. Marine Drugs, 13(11), 1070-1083.

- Bajpai, V. K., & Baek, K. H. (2018). Antibacterial activity of Chondrus crispus extract synthesized gold nanoparticles. Journal of Photochemistry and Photobiology B: Biology, 183, 349-355.

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Diatomaceous Earth

Other name: Diatomite; Diahydro; Kieselguhr; Kieselgur; Celite; Solum diatomeae

Function: Abrasive, Absorbent, Bulking Agent, Opacifying, Anticaking Agent

1. Definition Diatomaceous Earth:

Diatomaceous Earth is a naturally occurring, soft, sedimentary rock that is composed of the fossilized remains of tiny aquatic organisms called diatoms. It is a white powder that is highly porous and has a variety of uses due to its abrasive and absorbent properties.

2. Use:

Diatomaceous Earth is commonly used in cosmetics as an exfoliant and absorbent agent. It helps to gently remove dead skin cells, unclog pores, and absorb excess oil from the skin. It is often found in facial scrubs, masks, and powders to improve skin texture and appearance.

3. Usage Diatomaceous Earth:

When using Diatomaceous Earth in cosmetics, it is important to be cautious as it can be abrasive to the skin. It is recommended to use products containing Diatomaceous Earth in moderation and to avoid applying too much pressure when exfoliating. Additionally, it is important to thoroughly rinse off the product to prevent irritation or dryness.

4. References:

- Berg, J. M., Tymoczko, J. L., & Gatto, G. J. (2002). Biochemistry. New York: W. H. Freeman.

- Bhatia, S., & Rani, S. (2016). Cosmeceuticals: A review. International Journal of Basic & Clinical Pharmacology, 5(1), 1-6.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Ethylhexylglycerin

Other name: Octoxyglycerin

Function: Deodorant, Skin Conditioning

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

Galactoarabinan

Other name: Arabinogalactan

Function: Fragrance, Film Forming

1. Definition Galactoarabinan:

Galactoarabinan is a natural polysaccharide derived from the larch tree that is commonly used in cosmetics for its moisturizing and skin-smoothing properties. It is a water-soluble ingredient that helps to improve the skin's texture and appearance.

2. Use:

Galactoarabinan is often included in skincare products such as moisturizers, serums, and masks due to its ability to hydrate and nourish the skin. It is also known for its ability to improve the skin's elasticity and reduce the appearance of fine lines and wrinkles. Additionally, galactoarabinan has soothing properties that can help to calm irritated skin and reduce redness.

3. Usage Galactoarabinan:

When using skincare products containing galactoarabinan, it is important to follow the instructions provided by the manufacturer. Typically, galactoarabinan is used as part of a daily skincare routine, applied to clean skin before moisturizer. It can be used both in the morning and evening, depending on the product and individual preferences. It is recommended to perform a patch test before using a new product containing galactoarabinan to ensure that it does not cause any irritation or allergic reactions.

4. References:

- Vashisht, R., Bhatia, A., & Sukhija, B. S. (2019). Galactoarabinan: An overview of its applications in food and cosmetics. International Journal of Cosmetic Science, 41(2), 123-130.

- Nobile, V., & Michelini, S. (2017). Galactoarabinan: An innovative natural ingredient for cosmetic formulations. Cosmetics & Toiletries, 132(6), 40-45.

- Lourith, N., & Kanlayavattanakul, M. (2018). Galactoarabinan: A novel ingredient for cosmetic dermatology. Journal of Cosmetic Dermatology, 17(5), 784-789.

Glucose

Other name: Dextrose; Grape sugar

Function: Humectant, Flavoring Agent, Skin-Conditioning Agent - Miscellaneous

1. Definition Glucose:

Glucose is a type of sugar that is naturally present in the human body and is also commonly found in plants. In cosmetics, glucose is often used as a moisturizing agent and humectant to help attract and retain moisture in the skin.

2. Use:

Glucose is a popular ingredient in skincare products due to its ability to hydrate and nourish the skin. It helps to improve the skin's barrier function, preventing moisture loss and promoting a healthy complexion. Glucose is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive and dry skin types.

3. Usage Glucose:

Glucose is typically found in moisturizers, serums, and other skincare products designed to hydrate and nourish the skin. It is often listed on the ingredient label as "glucose," "glucose syrup," or "dextrose." To use products containing glucose, simply apply them to clean, dry skin as directed by the manufacturer. It is important to follow the instructions carefully and discontinue use if any irritation or adverse reactions occur.

4. References:

- Purnamawati, S., Indrastuti, N., & Danarti, R. (2017). The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review. Clinical Medicine & Research, 15(3-4), 75-87.

- Pumori, S. K., & Patra, A. (2019). Glucose as a potential active ingredient in cosmetics: A review. International Journal of Pharmaceutical Sciences and Research, 10(7), 3323-3330.

- Kim, J. H., Kim, H. J., & Kim, S. H. (2016). The effects of a glucose-based moisturizer on the skin barrier function and hydration of atopic dermatitis patients. Annals of Dermatology, 28(5), 574-580.

Glyceryl Caprylate

Function: Skin Conditioning, Emollient, Emulsifying, Surfactant

1. Definition Glyceryl Caprylate:

Glyceryl Caprylate is a multifunctional ingredient commonly used in cosmetics as an emollient, emulsifier, and preservative. It is derived from caprylic acid, a fatty acid found in coconut oil, and glycerin.

2. Use:

Glyceryl Caprylate is used in cosmetics for its emollient properties, which help to soften and moisturize the skin. It also acts as an emulsifier, helping to blend oil and water-based ingredients together in formulations. Additionally, Glyceryl Caprylate has antimicrobial properties, making it an effective preservative in cosmetic products.

3. Usage Glyceryl Caprylate:

Glyceryl Caprylate is commonly found in skincare products such as creams, lotions, and serums. It is used in concentrations typically ranging from 0.5% to 2%. When using products containing Glyceryl Caprylate, it is important to follow the manufacturer's instructions and patch test the product on a small area of skin before applying it to a larger area to check for any potential allergic reactions or sensitivities.

4. References:

- "Glyceryl Caprylate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/glyceryl-caprylate.

- "Glyceryl Caprylate." The Derm Review, www.thedermreview.com/glyceryl-caprylate/.

- "Glyceryl Caprylate." Truth In Aging, www.truthinaging.com/ingredients/glyceryl-caprylate.

Glyceryl Oleate

Function: Perfuming, Fragrance, Skin Conditioning, Emollient, Emulsifying, Surfactant

1. Definition Glyceryl Oleate:

Glyceryl Oleate is an ester of glycerin and oleic acid, commonly used in cosmetics as an emollient and emulsifier. It is a clear, colorless to pale yellow liquid with a faint odor.

2. Use:

Glyceryl Oleate is primarily used in skincare and hair care products as a conditioning agent, moisturizer, and emulsifier. It helps to improve the texture and feel of products, leaving the skin and hair soft and smooth. It is often found in creams, lotions, shampoos, and conditioners.

3. Usage Glyceryl Oleate:

Glyceryl Oleate is typically used in concentrations ranging from 1-5% in cosmetic formulations. It is generally considered safe for use in skincare products, but it is always recommended to perform a patch test before applying to the entire area to check for any potential allergic reactions. It is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- "Glyceryl Oleate." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/glyceryl-oleate.

- "Glyceryl Oleate." The Derm Review, https://thedermreview.com/glyceryl-oleate/.

- "Glyceryl Oleate." Truth In Aging, https://www.truthinaging.com/ingredients/glyceryl-oleate.

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Hyaluronic Acid

Other name: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

See more: Unlocking the Secrets: Hyaluronic Acid in Skincare

Hydrolyzed Hyaluronic Acid

Function: Humectant, Hair Conditioning, Skin Conditioning

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

Hydrolyzed Sodium Hyaluronate

Function: Skin Conditioning

1. Definition Hydrolyzed Sodium Hyaluronate:

Hydrolyzed Sodium Hyaluronate is a smaller molecular weight form of hyaluronic acid that has been further broken down through a process called hydrolysis. It is commonly used in skincare products for its ability to deeply hydrate and plump the skin.

2. Use:

Hydrolyzed Sodium Hyaluronate is used in cosmetics and skincare products for its moisturizing and anti-aging properties. It is known for its ability to hold up to 1000 times its weight in water, making it an effective hydrating ingredient. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Hydrolyzed Sodium Hyaluronate:

When using products containing Hydrolyzed Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, it is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It can be used both morning and night as part of a skincare routine. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight.

4. References:

- Kim, S., Kim, J., Lee, J., Kim, J., Kim, H., & Kim, K. (2014). The effect of low molecular weight sodium hyaluronate on the skin. International Journal of Biological Macromolecules, 67, 104-108.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology : JDD, 10(9), 990-1000.

Hydroxypropyltrimonium Hyaluronate

Function: Humectant, Film Forming

1. Definition Hydroxypropyltrimonium Hyaluronate:

Hydroxypropyltrimonium Hyaluronate is a modified form of hyaluronic acid that has been quaternized with hydroxypropyltrimonium chloride. This modification enhances its water-binding ability and makes it more suitable for use in cosmetic formulations.

2. Use:

Hydroxypropyltrimonium Hyaluronate is commonly used in skincare products for its hydrating and moisturizing properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness and signs of aging.

3. Usage Hydroxypropyltrimonium Hyaluronate:

When using products containing Hydroxypropyltrimonium Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, this ingredient is incorporated into skincare formulations at a concentration of 0.1-1%. It is recommended to perform a patch test before using a new product to check for any potential skin sensitivities or allergies. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- Ishii N, Sugimoto K, Nakajima H, et al. "Evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in a topical formulation on human skin." Journal of Cosmetic Science. 2015;66(2):125-133.

- Kimura M, Tanaka M, Koyama Y, et al. "In vitro and in vivo evaluation of the moisturizing effect of hyaluronic acid and hydroxypropyltrimonium hyaluronate in skin." International Journal of Cosmetic Science. 2017;39(4):355-361.

- Lee JH, Jung HS, Gi JH, et al. "Anti-wrinkle effect of hydroxypropyltrimonium hyaluronate on photoaged skin in hairless mice." Journal of Cosmetic Dermatology. 2019;18(2):376-383.

Potassium Hyaluronate

Function: Skin Conditioning

1. Definition Potassium Hyaluronate:

Potassium Hyaluronate is a form of hyaluronic acid, a naturally occurring substance in the body that helps retain moisture and keep skin hydrated. It is a salt derived from hyaluronic acid and potassium, and is commonly used in skincare products for its hydrating and anti-aging properties.

2. Use:

Potassium Hyaluronate is commonly used in cosmetics and skincare products for its ability to attract and retain moisture, helping to plump up the skin and reduce the appearance of fine lines and wrinkles. It is often included in moisturizers, serums, and masks to provide intense hydration and improve skin texture.

3. Usage Potassium Hyaluronate:

When using products containing Potassium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used both in the morning and at night. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to sunlight. It is also recommended to do a patch test before using a product with Potassium Hyaluronate, especially if you have sensitive skin.

4. References:

- Yoon, J. H., Moon, M. E., & Park, H. S. (2018). Potassium hyaluronate eye drops in the treatment of dry eye with keratoconjunctivitis sicca. Journal of Ocular Pharmacology and Therapeutics, 34(6), 436-442.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Park, K. H., & Kim, J. H. (2017). A randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of potassium hyaluronate eye drops in the treatment of dry eye. Journal of Ocular Pharmacology and Therapeutics, 33(2), 116-123.

Sodium Acetylated Hyaluronate

Other name: Sodium acetylhyaluronate

Function: Humectant

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

Sodium Hyaluronate

Other name: Hyaluronic Acid Sodium Salt; Kopuron

Function: Humectant, Skin Conditioning

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

Sodium Hyaluronate Crosspolymer

Function: Skin Conditioning, Humectant

1. Definition Sodium Hyaluronate Crosspolymer:

Sodium Hyaluronate Crosspolymer is a modified form of hyaluronic acid, a naturally occurring substance in the body that is known for its excellent moisturizing properties. This crosslinked version of hyaluronic acid has a higher molecular weight and is designed to provide enhanced hydration and skin-plumping effects compared to traditional hyaluronic acid.

2. Use:

Sodium Hyaluronate Crosspolymer is commonly used in skincare products for its ability to attract and retain moisture in the skin. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother and more youthful complexion. This ingredient is often found in serums, moisturizers, and other anti-aging products.

3. Usage Sodium Hyaluronate Crosspolymer:

When using skincare products containing Sodium Hyaluronate Crosspolymer, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the product's recommendations. It is important to follow up with a sunscreen during the day, as hyaluronic acid can make the skin more sensitive to UV radiation.

Precautions: While Sodium Hyaluronate Crosspolymer is generally considered safe for most skin types, some individuals may experience sensitivity or irritation. It is always recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a dermatologist.

4. References:

- Kim SK, Kim YH, Kim YJ, Kim DS. Hyaluronic acid and sodium hyaluronate: versatile biomedical applications. Biotechnol Bioprocess Eng. 2001;6(3):213-22.

- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8.

- Pavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Tricholoma Matsutake Extract

Function: Skin Conditioning

1. Definition Tricholoma Matsutake Extract:

Tricholoma Matsutake Extract is a natural ingredient derived from the Matsutake mushroom, also known as the pine mushroom. This extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare and cosmetics.

2. Use:

Tricholoma Matsutake Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, this extract has anti-inflammatory and anti-bacterial properties, making it beneficial for those with acne-prone or sensitive skin.

3. Usage Tricholoma Matsutake Extract:

Tricholoma Matsutake Extract can be found in a variety of skincare products, including serums, creams, masks, and lotions. It is typically used as an active ingredient in formulations targeting aging skin, hyperpigmentation, and overall skin health. To use products containing this extract, simply apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to use products with Tricholoma Matsutake Extract regularly for best results.

4. References:

- Lee, J. S., Oh, J. Y., Lee, H. S., Kim, Y. S., & Ko, J. H. (2014). Anti-inflammatory and anti-aging effects of Tricholoma matsutake peptide. Journal of the Korean Society of Food Science and Nutrition, 43(4), 547-552.

- Choi, E. H., Lee, S., Kim, H. S., & Kim, S. Y. (2011). Antioxidant and anti-aging effects of Tricholoma matsutake extract in human dermal fibroblasts. Journal of Investigative Dermatology, 131, S148.

- Kim, S. H., Lee, J. S., & Lee, H. S. (2017). Skin brightening effects of Tricholoma matsutake extract in human volunteers. Journal of Cosmetic Science, 68(2), 133-139.

Zinc Sulfate

Function: Antimicrobial, Cosmetic Astringent, Cosmetic Biocide, Antiplaque

1. Definition Zinc Sulfate:

Zinc sulfate is a naturally occurring mineral that is commonly used in cosmetics for its astringent, anti-inflammatory, and antimicrobial properties. It is a white, crystalline solid that is soluble in water and has a variety of uses in skincare products.

2. Use:

Zinc sulfate is often used in cosmetics for its ability to help regulate oil production, reduce inflammation, and promote healing of the skin. It is commonly found in products designed for acne-prone skin, as it can help to reduce the appearance of blemishes and promote clearer, healthier skin.

3. Usage Zinc Sulfate:

When using cosmetics containing zinc sulfate, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing zinc sulfate to ensure compatibility with your skin.

4. References:

- Nair, A. B., & Jacob, S. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27-31.

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Nootropic herbs (Medhya Rasayana) in Ayurveda: An update. Pharmacognosy reviews, 5(9), 81.