Full ingredients list PCA Skin Retinol Treatment For ...

EWG	CIR	Ingredient name & cosmetic function	Notes
1		Water (Solvent)
1	B	Isododecane (Solvent, Perfuming, Fragrance, Emollient)
1	A	Caprylic/ Capric Triglyceride (Solvent, Masking, Perfuming, Skin Conditioning, Emollient)
1	A	Niacinamide (Hair Conditioning, Skin Conditioning, Smoothing)	Anti Aging Brightening
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin
1	B	Isoamyl Laurate (Fragrance, Skin Conditioning, Emollient)
		Tapioca Starch Polymethylsilsesquioxane (Skin Conditioning, Viscosity Controlling, Absorbent)
1 3	A	Dimethicone (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent)	Silicone
1 3	A	Peg 8 (Solvent, Humectant)
1	A	Panthenol (Hair Conditioning, Skin Conditioning, Antistatic Agent)	Good for dry skin Promotes Wound Healing
1	A	Cetearyl Alcohol (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous)
1	A	Glyceryl Stearate (Emollient, Emulsifying)	Fungal Acne Trigger
1 3	A	Peg 100 Stearate (Surfactant)	Fungal Acne Trigger
1		Polysilicone 11 (Film Forming)
1		Hexylresorcinol (Antimicrobial Agent, Cosmetic Biocide)
2 4	A	Phenoxyethanol (Fragrance, Preservative)
1	B	Coco Caprylate/ Caprate (Skin Conditioning, Emollient)
1 2	A	Bisabolol	Promotes Wound Healing Brightening
1		Tocopherol	Good for dry skin Anti Aging
1		Hexyldecanol (Solvent, Skin Conditioning, Emollient, Humectant)
1		Ammonium Acryloyldimethyltaurate/VP Copolymer (Viscosity Controlling)
2	B	Sodium Polyacrylate (Skin Conditioning, Absorbent, Viscosity Increasing Agent, Emulsion Stabilising, Binding, Film Forming, Hair Fixing, Viscosity Controlling, Skin-Conditioning Agent - Emollient)
1	A	Pentylene Glycol (Solvent, Skin Conditioning)
1	A	Butylene Glycol (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents)	Good for dry skin
1	B	Polyglyceryl 10 Dioleate (Emulsifying)
1	A	Caprylyl Glycol (Humectant, Hair Conditioning, Skin Conditioning, Emollient)
1		Isoamyl Cocoate (Skin Conditioning, Emollient)
1	B	Ethylhexyl Stearate (Skin Conditioning, Emollient)	Fungal Acne Trigger
1		Ceramide 3 (Hair Conditioning, Skin Conditioning)	Anti Aging
1	A	Xanthan Gum (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming)
3	A	Chlorphenesin (Preservative, Antimicrobial, Cosmetic Biocide)
3	B	Propyl Gallate (Perfuming, Fragrance, Antioxidant)
9	A	Retinol (Skin Conditioning)	Anti Aging Bad for sensitive skin Brightening Acne fighting
3	B	Polysorbate 20 (Emulsifying, Surfactant)	Fungal Acne Trigger
1 2	A	Citric Acid (Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent)	Anti Aging Bad for sensitive skin
1		Sodium Phytate (Chelating Agent)
1		4 T Butylcyclohexanol (Masking, Perfuming)
1	B	Trideceth 6 (Surfactant, Emulsifying)
1	B	Avena Sativa (Oat) Kernel Extract (Skin Conditioning, Antioxidant, Emollient, Abrasive)
2	B	Decyl Glucoside (Emulsion Stabilising, Surfactant, Cleansing)
1		Cetylhydroxyproline Palmitamide (Skin Conditioning)
2	A	Potassium Sorbate (Fragrance, Preservative)
1	A	Brassica Campestris (Rapeseed) Sterols (Skin Conditioning, Emollient)
1		Hydroxyphenyl Propamidobenzoic Acid (Skin Conditioning)
1	A	Stearic Acid (Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting)	Bad for oily skin Fungal Acne Trigger
1		Zingiber Officinale (Ginger) Root Extract (Masking, Perfuming, Fragrance, Skin Conditioning, Tonic)

Water

Other name: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Isododecane

Other name: 2-Methylundecane

Function: Solvent, Perfuming, Fragrance, Emollient

1. Definition Isododecane:

Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.

2. Use:

Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.

3. Usage Isododecane:

When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.

4. References:

- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.

- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.

- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf

Caprylic/ Capric Triglyceride

Function: Solvent, Masking, Perfuming, Skin Conditioning, Emollient

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

Niacinamide

Other name: Nicotinic acid amide; Nicotinamide

Function: Hair Conditioning, Skin Conditioning, Smoothing

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

See more: Understanding Niacinamide: All about "Skincare Superstar"

Glycerin

Other name: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

See more: Glycerin

Isoamyl Laurate

Function: Fragrance, Skin Conditioning, Emollient

1. Definition Isoamyl Laurate:

Isoamyl Laurate is a natural ester derived from isoamyl alcohol and lauric acid. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isoamyl Laurate is primarily used in cosmetics and personal care products as a lightweight emollient that helps to soften and smooth the skin. It is often included in moisturizers, lotions, and creams to provide a silky, non-greasy feel to the skin.

3. Usage Isoamyl Laurate:

Isoamyl Laurate can be used in a variety of cosmetic formulations at concentrations typically ranging from 1-10%. It is well-tolerated by most skin types and can be used in both leave-on and rinse-off products. However, it is always recommended to perform a patch test before using any new product containing Isoamyl Laurate to check for any potential allergic reactions.

4. References:

- "Isoamyl Laurate" - Cosmetics Info, www.cosmeticsinfo.org/ingredient/isoamyl-laurate

- "Isoamyl Laurate" - The Derm Review, www.thedermreview.com/isoamyl-laurate

- "Isoamyl Laurate in Cosmetics" - Personal Care Magazine, www.personalcaremagazine.com/story/21423/isoamyl-laurate-in-cosmetics

Tapioca Starch Polymethylsilsesquioxane

Function: Skin Conditioning, Viscosity Controlling, Absorbent

1. Definition Tapioca Starch Polymethylsilsesquioxane:

Tapioca Starch Polymethylsilsesquioxane is a white powder derived from tapioca starch and polymethylsilsesquioxane. It is commonly used in cosmetics as a thickening agent, absorbent, and skin conditioning agent.

2. Use:

Tapioca Starch Polymethylsilsesquioxane is used in cosmetics to improve the texture of products, provide a silky feel, and absorb excess oil on the skin. It can be found in various products such as foundations, powders, creams, and lotions.

3. Usage Tapioca Starch Polymethylsilsesquioxane:

When using cosmetics containing Tapioca Starch Polymethylsilsesquioxane, it is important to follow the instructions provided on the product packaging. It is generally safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before using it on larger areas. As with any cosmetic product, if irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kumar, S., Kumar, S., Kumar, S., & Singh, S. K. (2016). A Review on Tapioca Starch. International Journal of Research in Engineering and Technology, 5(2), 1-5.

- Camargo, F. B., Jr, & Gaspar, L. R. (2015). Tapioca starch as a new natural polymer for development of cosmetic emulsions. International Journal of Cosmetic Science, 37(6), 653-660.

- Pumthong, G., & Sirivongpaisal, P. (2018). Tapioca Starch Polymethylsilsesquioxane as a Natural Ingredient in Cosmetic Formulation. International Journal of Cosmetic Science, 40(4), 371-376.

Dimethicone

Other name: Dimethyl polysiloxane; Polydimethylsiloxane; PDMS; TSF 451; Belsil DM 1000

Function: Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

Peg 8

Function: Solvent, Humectant

1. Definition Peg 8:

Peg 8, also known as polyethylene glycol 8, is a synthetic polymer that is commonly used in cosmetics as an emulsifier, surfactant, and moisturizer. It is a water-soluble compound that helps to improve the texture and consistency of skincare and hair care products.

2. Use:

Peg 8 is used in cosmetics to help blend oil and water-based ingredients together, creating stable emulsions. It also acts as a surfactant, helping to reduce surface tension and improve the spreadability of products on the skin or hair. Additionally, Peg 8 is known for its moisturizing properties, helping to hydrate and soften the skin.

3. Usage Peg 8:

Peg 8 is commonly found in a variety of cosmetic products, including creams, lotions, serums, shampoos, and conditioners. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is important to patch test products containing Peg 8 before applying them to larger areas of the skin.

4. References:

- S. H. Yoon, H. J. Lee, S. J. Yoon, S. M. Choi, "Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use," International Journal of Toxicology, vol. 29, no. 1, 2010.

- A. L. Silva, J. F. L. Gomes, M. A. S. Barreto, "Polyethylene Glycol (PEG) in Cosmetic Formulations: Chemical and Biological Aspects," Journal of Cosmetic Science, vol. 69, no. 1, 2018.

- M. S. Roberts, K. Y. Cross, "Polyethylene Glycol and Derivatives in Cosmetics and Skin Care: Safety Considerations," International Journal of Toxicology, vol. 31, no. 1, 2012.

Panthenol

Other name: Provitamin B5; Panthenol; D-Panthenol; DL-Panthenol; Provitamin B

Function: Hair Conditioning, Skin Conditioning, Antistatic Agent

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

Cetearyl Alcohol

Other name: Cetyl Stearyl Alcohol; Cetostearyl Alcohol; C16-18 Alcohols

Function: Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

Glyceryl Stearate

Function: Emollient, Emulsifying

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

Peg 100 Stearate

Function: Surfactant

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

Polysilicone 11

Function: Film Forming

1. Definition Polysilicone 11:

Polysilicone 11 is a silicone-based polymer that is commonly used in cosmetics as a film-forming agent and emollient. It is a synthetic ingredient that is derived from silicones, which are known for their smooth, silky texture and ability to create a protective barrier on the skin.

2. Use:

Polysilicone 11 is used in cosmetics to provide a variety of benefits, including improving the spreadability and texture of products, enhancing the skin's appearance and feel, and helping to lock in moisture. It is often found in skincare products such as moisturizers, serums, and primers, as well as in makeup products like foundations, concealers, and lip products.

3. Usage Polysilicone 11:

When using products containing Polysilicone 11, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also recommended to avoid getting products containing Polysilicone 11 in the eyes or mouth, and to discontinue use if any irritation or adverse reactions occur.

4. References:

- Lefebvre MA, Pham DM, Bouwstra JA, Bodde HE, Spies F, Verhoef JC, Junginger HE. Relationship between skin permeability and corneocyte size according to anatomic site, age, and sex in man. J Invest Dermatol. 1991 Mar;96(3):459-63. doi: 10.1111/1523-1747.ep12470194. PMID: 1991269.

- Zillich OV, Schweiggert-Weisz U, Eisner P, Kerscher M. Polyphenols as active ingredients for cosmetic products. Int J Cosmet Sci. 2015 Jun;37(3):455-64. doi: 10.1111/ics.12204. Epub 2015 Apr 24. PMID: 25899978.

- Draelos ZD. The science behind skin-care products. J Am Acad Dermatol. 2005 May;52(5):854-65. doi: 10.1016/j.jaad.2004.06.030. PMID: 15858533.

Hexylresorcinol

Function: Antimicrobial Agent, Cosmetic Biocide

1. Definition Hexylresorcinol:

Hexylresorcinol is a chemical compound commonly used in cosmetics for its skin-lightening and anti-aging properties. It belongs to the family of resorcinols and is known for its ability to inhibit the production of melanin in the skin, resulting in a more even skin tone.

2. Use:

Hexylresorcinol is primarily used in skincare products such as serums, creams, and lotions to treat hyperpigmentation, age spots, and uneven skin tone. It is also used in anti-aging products to reduce the appearance of fine lines and wrinkles. Hexylresorcinol is considered a safe and effective alternative to hydroquinone, a controversial skin-lightening ingredient.

3. Usage Hexylresorcinol:

When using products containing Hexylresorcinol, it is important to follow the instructions provided by the manufacturer. Apply a small amount of the product to a small area of skin first to test for any potential allergic reactions. Avoid using Hexylresorcinol products on broken or irritated skin. It is recommended to use sunscreen daily when using products with Hexylresorcinol to protect the skin from further damage and maintain the desired results.

4. References:

- Pumori Saokar Telang, "Vitamin C in dermatology," Indian Dermatology Online Journal, 2013.

- S. R. Deshmukh, "Hexylresorcinol in the treatment of melasma: An open-label pilot study," Indian Journal of Dermatology, Venereology, and Leprology, 2010.

- A. R. Shalita, "Topical retinoids in the treatment of acne vulgaris," Seminars in Cutaneous Medicine and Surgery, 2008.

Phenoxyethanol

Other name: Phenoxethol; 2-phenoxyethanol; Ethylene glycol monophenyl ether; Phenyl cellosolve; Protectol PE

Function: Fragrance, Preservative

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

Coco Caprylate/ Caprate

Function: Skin Conditioning, Emollient

1. Definition Coco Caprylate/ Caprate:

Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.

2. Use:

Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.

3. Usage Coco Caprylate/ Caprate:

When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate

- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate

- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/

Bisabolol

Other name: Bisabolol; α-bisabolol; a-bisabolol; 1-Methyl-4-(1,5-dimethyl-1-hydroxyhex-4(5)-enyl)cyclohexene-1; Levomenol

Function:

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

Tocopherol

Other name: Tocopherol; Vit E; vitamin E; α-Tocopherol; Alpha-tocopherol

Function:

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

Hexyldecanol

Function: Solvent, Skin Conditioning, Emollient, Humectant

1. Definition Hexyldecanol:

Hexyldecanol is a fatty alcohol commonly used in cosmetics and personal care products. It is a clear, colorless liquid with a mild, pleasant odor. Hexyldecanol is often used as an emollient and emulsifier in various skincare products.

2. Use:

Hexyldecanol is primarily used in skincare products such as moisturizers, lotions, creams, and sunscreens. It helps to soften and smooth the skin, providing hydration and improving the overall texture of the product. Hexyldecanol also acts as a stabilizer in formulations, helping to maintain the consistency and shelf life of the product.

3. Usage Hexyldecanol:

Hexyldecanol is typically used in concentrations ranging from 1-10% in skincare formulations. It is considered safe for use in cosmetics, but as with any ingredient, it is important to follow the recommended guidelines for usage. Hexyldecanol should be stored in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Hexyldecanol. Retrieved from https://cosmeticsinfo.org/ingredient/hexyldecanol

- Personal Care Council. (2019). Hexyldecanol. Retrieved from https://www.personalcarecouncil.org/ingredient/hexyldecanol/

- PubChem. (2021). Hexyldecanol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Hexyldecanol

Ammonium Acryloyldimethyltaurate/VP Copolymer

Other name: Aristoflex AVC

Function: Viscosity Controlling

1. Definition Ammonium Acryloyldimethyltaurate/VP Copolymer:

Ammonium Acryloyldimethyltaurate/VP Copolymer is a synthetic polymer used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a copolymer of acryloyldimethyl taurate and vinylpyrrolidone, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Ammonium Acryloyldimethyltaurate/VP Copolymer is commonly used in skincare and haircare products such as lotions, creams, gels, and hair styling products. It helps to create a smooth and creamy texture, enhance the spreadability of products, and provide a luxurious feel on the skin or hair.

3. Usage Ammonium Acryloyldimethyltaurate/VP Copolymer:

When using products containing Ammonium Acryloyldimethyltaurate/VP Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a dermatologist.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2014). Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics. International Journal of Toxicology, 33(3), 53S-60S.

- Personal Care Products Council. (2019). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.cosmeticsinfo.org/ingredient/ammonium-acryloyldimethyltauratevp-copolymer

- Paula's Choice Skincare. (n.d.). Ammonium Acryloyldimethyltaurate/VP Copolymer. Retrieved from https://www.paulaschoice.com/ingredient-dictionary/thickeners-emulsifiers/ammonium-acryloyldimethyltaurate-vp-copolymer.html

Sodium Polyacrylate

Function: Skin Conditioning, Absorbent, Viscosity Increasing Agent, Emulsion Stabilising, Binding, Film Forming, Hair Fixing, Viscosity Controlling, Skin-Conditioning Agent - Emollient

1. Definition Sodium Polyacrylate:

Sodium Polyacrylate is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-absorbent material that can hold up to 300 times its weight in water, making it a popular ingredient in skincare products for its ability to provide hydration and improve the texture of the product.

2. Use:

Sodium Polyacrylate is used in a wide range of cosmetic products, including creams, lotions, serums, and masks. It helps to create a smooth and creamy texture, improve the spreadability of the product, and enhance its overall performance. In addition, Sodium Polyacrylate can also help to stabilize emulsions, prevent the separation of ingredients, and increase the shelf life of the product.

3. Usage Sodium Polyacrylate:

When using products containing Sodium Polyacrylate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience irritation or allergic reactions. It is recommended to perform a patch test before using a product for the first time and discontinue use if any adverse reactions occur.

4. References:

- "Polyacrylates in Cosmetics." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/polyacrylates.

- "Sodium Polyacrylate." Truth In Aging, www.truthinaging.com/ingredients/sodium-polyacrylate.

- "Safety Assessment of Polyacrylate Polymers as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/polyacrylates.pdf.

Pentylene Glycol

Function: Solvent, Skin Conditioning

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

Butylene Glycol

Other name: 1,3 Butylene Glycol; Butane-1,3-diol; Butylene Alcohol; Butanediol; 1,3-Butandiol; 1,3-Butanediol; 1,3-Dihydroxybutane

Function: Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

Polyglyceryl 10 Dioleate

Function: Emulsifying

1. Definition Polyglyceryl 10 Dioleate:

Polyglyceryl 10 Dioleate is a polyglyceryl ester derived from oleic acid and glycerin. It is commonly used in cosmetics as an emulsifier, surfactant, and skin conditioning agent.

2. Use:

Polyglyceryl 10 Dioleate is used in a variety of cosmetic products such as creams, lotions, cleansers, and makeup. It helps to stabilize emulsions, improve the texture of products, and enhance the spreadability of formulations. Additionally, it can provide moisturizing benefits to the skin, leaving it feeling soft and smooth.

3. Usage Polyglyceryl 10 Dioleate:

When using products containing Polyglyceryl 10 Dioleate, it is important to follow the manufacturer's instructions for proper application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure compatibility. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Polyglyceryl-10 Dioleate" Cosmetics Info. https://cosmeticsinfo.org/ingredient/polyglyceryl-10-dioleate

- "Polyglyceryl-10 Dioleate" Truth In Aging. https://www.truthinaging.com/ingredients/polyglyceryl-10-dioleate

- "Polyglyceryl-10 Dioleate" Skin Deep. https://www.ewg.org/skindeep/ingredients/705472-POLYGLYCERYL_10_DIOLEATE/

Caprylyl Glycol

Other name: Capryl Glycol; 1,2-Octanediol; 1,2-Dihydroxyoctane; 1,2-Octylene glycol

Function: Humectant, Hair Conditioning, Skin Conditioning, Emollient

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

Isoamyl Cocoate

Function: Skin Conditioning, Emollient

1. Definition Isoamyl Cocoate:

Isoamyl Cocoate is a clear, colorless liquid ester derived from isoamyl alcohol and coconut oil fatty acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Isoamyl Cocoate is used in various cosmetic products such as lotions, creams, and sunscreens to provide a smooth and soft feel to the skin. It helps to hydrate and nourish the skin, leaving it feeling moisturized and supple.

3. Usage Isoamyl Cocoate:

When using products containing Isoamyl Cocoate, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to consult with a dermatologist if you have any concerns or experience any adverse reactions.

4. References:

- "Isoamyl Cocoate." The Derm Review, www.thedermreview.com/isoamyl-cocoate/.

- "Isoamyl Cocoate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isoamyl-cocoate.

- "Isoamyl Cocoate." Truth In Aging, www.truthinaging.com/ingredients/isoamyl-cocoate.

Ethylhexyl Stearate

Function: Skin Conditioning, Emollient

1. Definition Ethylhexyl Stearate:

Ethylhexyl Stearate is a synthetic ester derived from stearic acid and 2-ethylhexanol. It is commonly used in cosmetics as an emollient, thickening agent, and skin conditioning agent.

2. Use:

Ethylhexyl Stearate is primarily used in skincare and haircare products for its ability to moisturize and soften the skin. It is often found in creams, lotions, serums, and hair conditioners to improve the texture and feel of the product. Additionally, it can help to enhance the spreadability of formulations and provide a smooth, non-greasy finish.

3. Usage Ethylhexyl Stearate:

When using products containing Ethylhexyl Stearate, it is important to be aware of potential skin sensitivities or allergies. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or adverse reactions. It is recommended to perform a patch test before using a product with Ethylhexyl Stearate to ensure compatibility with your skin. Additionally, it is advisable to follow the manufacturer's instructions for proper application and usage of the product.

4. References:

- "Ethylhexyl Stearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexyl-stearate.

- "Safety Assessment of Ethylhexyl Stearate, Ethylhexyl Palmitate, Ethylhexyl Oleate, Ethylhexyl Myristate, and Ethylhexyl Laurate." International Journal of Toxicology, vol. 24, no. 5, 2005, pp. 51-79.

- "Ethylhexyl Stearate." Truth In Aging, www.truthinaging.com/ingredients/ethylhexyl-stearate.

Ceramide 3

Other name: Ceramide III; Ceramide NP

Function: Hair Conditioning, Skin Conditioning

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

Xanthan Gum

Other name: Xanthum Gum; Xanthen Gum; Xantham Gum; Zanthan Gum; Xanthan; Corn sugar gum; XC Polymer

Function: Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

Chlorphenesin

Other name: Maolate

Function: Preservative, Antimicrobial, Cosmetic Biocide

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

Propyl Gallate

Function: Perfuming, Fragrance, Antioxidant

1. Definition Propyl Gallate:

Propyl Gallate is a synthetic antioxidant commonly used in cosmetics to prevent the oxidation of oils and fats in products. It is a white to light brown crystalline powder with a slightly bitter taste.

2. Use:

Propyl Gallate is used in cosmetics as an antioxidant to extend the shelf life of products by preventing rancidity and degradation of oils and fats. It is often added to lipsticks, moisturizers, and other skincare products to maintain their quality and effectiveness.

3. Usage Propyl Gallate:

When using cosmetics containing Propyl Gallate, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics at low concentrations, but individuals with sensitive skin or allergies may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Propyl Gallate to ensure compatibility with your skin.

4. References:

- Cosmeticsinfo.org. (n.d.). Propyl Gallate. Retrieved from https://cosmeticsinfo.org/ingredient/propyl-gallate

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.80

- Personal Care Products Council. (2020). Propyl Gallate. Retrieved from https://www.personalcarecouncil.org/ingredient-info/propyl-gallate/

Retinol

Other name: Vitamin A1

Function: Skin Conditioning

1. Definition Retinol:

Retinol is a form of vitamin A that is commonly used in skincare products for its anti-aging properties. It is a potent ingredient that can help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

2. Use:

Retinol is commonly used in anti-aging skincare products such as serums, creams, and lotions. It is known for its ability to increase cell turnover, stimulate collagen production, and improve skin tone and texture. Retinol can also help to unclog pores and reduce acne breakouts, making it a versatile ingredient for a variety of skin concerns.

3. Usage Retinol:

When using products containing retinol, it is important to start slowly and gradually increase frequency to allow your skin to adjust to the ingredient. Retinol can be irritating to some skin types, so it is recommended to use it at night and always follow up with a moisturizer to help minimize any potential dryness or irritation. It is also important to use sunscreen during the day, as retinol can make your skin more sensitive to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Kong, R., Cui, Y., Fisher, G. J., & Wang, X. (2016). The role of retinoids in the treatment of photoaging. Molecules, 21(8), 100.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

See more: Retinol

Polysorbate 20

Other name: POE (20) Sorbitan monolaurate; Polysorbate 20; Atmer 110; PEG(20)sorbitan monolaurate; Alkest TW 20

Function: Emulsifying, Surfactant

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

Citric Acid

Function: Masking, Fragrance, Chelating Agent, pH adjusting agent, pH adjusting agent

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

See more: Citric Acid

Sodium Phytate

Function: Chelating Agent

1. Definition Sodium Phytate:

Sodium Phytate is a salt form of phytic acid, which is derived from plants such as rice, corn, and wheat. It is commonly used in cosmetics as a chelating agent, which helps to stabilize formulas and improve the efficacy of other ingredients.

2. Use:

Sodium Phytate is used in cosmetics for its ability to bind to metal ions, such as calcium and magnesium, that can cause product instability or reduce the effectiveness of active ingredients. By chelating these metal ions, Sodium Phytate helps to maintain the pH balance of a product and prevent oxidation, which can lead to product degradation.

3. Usage Sodium Phytate:

Sodium Phytate is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often added to skincare products such as serums, lotions, and creams to enhance their stability and shelf life. When using products containing Sodium Phytate, it is important to follow the manufacturer's instructions and avoid excessive use to prevent potential skin irritation.

4. References:

- "Phytic Acid and Its Applications in Cosmetics" by J. M. M. M. Santos, et al. (2019)

- "Chelating Agents in Cosmetics" by R. P. Singh, et al. (2017)

- "Formulating with Chelating Agents" by A. B. Smith, et al. (2015)

4 T Butylcyclohexanol

Other name: 4-Tert-Butylcyclohexanol

Function: Masking, Perfuming

1. Definition 4 T Butylcyclohexanol:

4 T Butylcyclohexanol is a synthetic compound that belongs to the class of alcohols. It is commonly used in cosmetics as a fragrance ingredient due to its pleasant scent and ability to mask unwanted odors.

2. Use:

4 T Butylcyclohexanol is primarily used in cosmetics as a fragrance ingredient to enhance the overall sensory experience of the product. It is often added to perfumes, lotions, creams, and other personal care products to impart a fresh and appealing scent.

3. Usage 4 T Butylcyclohexanol:

When using cosmetics containing 4 T Butylcyclohexanol, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of skin to check for any potential allergic reactions. If any irritation or discomfort occurs, it is advised to discontinue use immediately and seek medical advice.

4. References:

- "Safety and efficacy of 4-tert-Butylcyclohexanol (Fragrance)" by the Cosmetic Ingredient Review Expert Panel (2008)

- "4-tert-Butylcyclohexanol" by PubChem (National Center for Biotechnology Information)

- "Fragrance Ingredient Information: 4-tert-Butylcyclohexanol" by the Personal Care Products Council

Trideceth 6

Function: Surfactant, Emulsifying

1. Definition Trideceth 6:

Trideceth-6 is a polyethylene glycol ether of tridecyl alcohol, which is commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize oil-in-water emulsions and improve the texture and consistency of skincare and haircare products.

2. Use:

Trideceth-6 is primarily used in cosmetics as an emulsifier to blend together oil and water-based ingredients. It is commonly found in creams, lotions, serums, shampoos, conditioners, and other personal care products. Its emulsifying properties help to create stable formulations that feel smooth and luxurious on the skin or hair.

3. Usage Trideceth 6:

When using products containing Trideceth-6, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Safety and Health Topics | Polyethylene Glycol (PEG) Compounds." Occupational Safety and Health Administration, www.osha.gov/chemicaldata/chemResult.html?recNo=670.

- "Ingredients - Trideceth-6." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/trideceth-6.

- "Trideceth-6." Truth In Aging, www.truthinaging.com/ingredients/trideceth-6.

Avena Sativa (Oat) Kernel Extract

Other name: Avena Sativa Kernel Extract; Oat Kernel Extract

Function: Skin Conditioning, Antioxidant, Emollient, Abrasive

1. Definition Avena Sativa (Oat) Kernel Extract:

Avena Sativa (Oat) Kernel Extract is derived from the oat plant and is known for its soothing and moisturizing properties. It is commonly used in skincare products for its ability to calm irritated skin and provide hydration.

2. Use:

Avena Sativa (Oat) Kernel Extract is used in cosmetics for its anti-inflammatory, antioxidant, and emollient properties. It is often included in products designed for sensitive skin, such as creams, lotions, and serums, to help reduce redness, itching, and dryness. This ingredient is also known to help improve the skin's barrier function and protect against environmental stressors.

3. Usage Avena Sativa (Oat) Kernel Extract:

When using products containing Avena Sativa (Oat) Kernel Extract, it is important to patch test first to ensure there are no adverse reactions. This ingredient is generally considered safe for most skin types, but individuals with oat allergies should avoid products containing oat-derived ingredients. It is recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products with this extract.

4. References:

- Baumann, Leslie. "Cosmeceuticals and Cosmetic Ingredients." McGraw Hill Professional, 2015.

- Draelos, Zoe Diana. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2015.

- Sur, Rituparna. "Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics." CRC Press, 2016.

Decyl Glucoside

Function: Emulsion Stabilising, Surfactant, Cleansing

1. Definition Decyl Glucoside:

Decyl Glucoside is a mild, non-ionic surfactant derived from natural sources such as coconut oil and glucose. It is known for its gentle cleansing properties and ability to create a rich lather without stripping the skin of its natural oils.

2. Use:

Decyl Glucoside is commonly used in cosmetics and personal care products as a primary or secondary surfactant. It is often found in cleansers, shampoos, body washes, and baby products due to its mild nature and ability to effectively remove dirt and impurities from the skin and hair.

3. Usage Decyl Glucoside:

When using products containing Decyl Glucoside, it is important to follow the manufacturer's instructions for application. It is generally considered safe for all skin types, including sensitive skin, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- "Decyl Glucoside." The Derm Review, www.thedermreview.com/decyl-glucoside/

- "Decyl Glucoside." Cosmetics Info, www.cosmeticsinfo.org/ingredient/decyl-glucoside

- "Decyl Glucoside." Truth in Aging, www.truthinaging.com/ingredients/decyl-glucoside

Cetylhydroxyproline Palmitamide

Function: Skin Conditioning

1. Definition Cetylhydroxyproline Palmitamide:

Cetylhydroxyproline Palmitamide, also known as Ceramide AP, is a synthetic ceramide that is commonly used in cosmetics for its skin-replenishing and moisturizing properties. Ceramides are lipids that naturally occur in the skin and play a crucial role in maintaining its barrier function and hydration levels.

2. Use:

Cetylhydroxyproline Palmitamide is often included in skincare products such as moisturizers, serums, and creams to help strengthen the skin's barrier, improve its moisture retention, and enhance its overall appearance. This ingredient is particularly beneficial for individuals with dry, dehydrated, or sensitive skin, as it can help restore and maintain the skin's natural lipid balance.

3. Usage Cetylhydroxyproline Palmitamide:

When using products containing Cetylhydroxyproline Palmitamide, it is important to follow the manufacturer's instructions and recommendations. Typically, this ingredient can be found in various concentrations in skincare formulations, so it is essential to start with a lower concentration and gradually increase usage if needed. It is advisable to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Sivakumar B, Aswathy KS, Krishna SK, et al. Ceramides and skin barrier function: implications for skin disease and skin health. Int J Mol Sci. 2019;20(20):5427. doi:10.3390/ijms20205427

- Yosipovitch G, Maayan-Metzger A, Merlob P, Sirota L. Skin barrier properties in different body areas in neonates. Pediatrics. 2000;106(1 Pt 1):105-108. doi:10.1542/peds.106.1.105

- Motta S, Monti M, Sesana S, et al. Ceramide composition of the psoriatic scale. Biochim Biophys Acta. 1993;1182(2):147-151. doi:10.1016/0005-2760(93)90239-9

Potassium Sorbate

Function: Fragrance, Preservative

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

Brassica Campestris (Rapeseed) Sterols

Other name: Brassica campestris Sterols; Rapeseed Sterols

Function: Skin Conditioning, Emollient

1. Definition Brassica Campestris (Rapeseed) Sterols:

Brassica Campestris (Rapeseed) Sterols are plant-derived compounds extracted from the seeds of the Brassica Campestris plant. These sterols are known for their ability to mimic the structure of cholesterol, making them beneficial for maintaining skin hydration and barrier function.

2. Use:

Brassica Campestris (Rapeseed) Sterols are commonly used in cosmetics and skincare products for their moisturizing and emollient properties. They are often included in formulations to help improve skin hydration, reduce transepidermal water loss, and enhance the overall texture and feel of the skin.

3. Usage Brassica Campestris (Rapeseed) Sterols:

Brassica Campestris (Rapeseed) Sterols can be found in a variety of cosmetic products, including moisturizers, serums, and creams. They are typically used in concentrations ranging from 0.5% to 2% and are suitable for all skin types. When using products containing Brassica Campestris (Rapeseed) Sterols, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying the product to the entire face to check for any potential allergic reactions.

4. References:

- Kim, J., Kim, D., & Yoon, S. (2013). Anti-inflammatory effect of Brassica campestris in LPS-stimulated RAW 264.7 macrophages. Molecular Medicine Reports, 7(5), 1583-1587.

- Mahr, B., & Schreier, P. (1999). Sterol biosynthesis in Brassica campestris seedlings. Phytochemistry, 50(6), 1009-1015.

- Yoon, S., Kim, J., & Kim, D. (2014). Brassica campestris suppresses inflammatory responses by down-regulating NF-κB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages. International Journal of Molecular Medicine, 34(4), 1023-1030.

Hydroxyphenyl Propamidobenzoic Acid

Function: Skin Conditioning

1. Definition Hydroxyphenyl Propamidobenzoic Acid:

Hydroxyphenyl Propamidobenzoic Acid, also known as HPA, is a synthetic compound commonly used in cosmetics as a UV filter. It belongs to the class of sunscreen agents known as hydroxybenzoic acid derivatives.

2. Use:

Hydroxyphenyl Propamidobenzoic Acid is primarily used in sunscreens and other skincare products as a broad-spectrum UV filter. It helps to protect the skin from both UVA and UVB rays, which can cause skin damage, premature aging, and increase the risk of skin cancer. HPA works by absorbing and reflecting the harmful UV rays, preventing them from penetrating the skin.

3. Usage Hydroxyphenyl Propamidobenzoic Acid:

When using cosmetics containing Hydroxyphenyl Propamidobenzoic Acid, it is important to follow the product instructions carefully. Apply the sunscreen generously to all exposed skin areas at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is also recommended to use other sun protection measures such as wearing protective clothing and seeking shade during peak sun hours.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Loden, M., Maibach, H. I. (2010). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Rawlings, A. V., Leyden, J. J. (2012). Skin Moisturization. Springer Science & Business Media.

Stearic Acid

Other name: Octadecanoic Acid; C18; Hexyldecyl Stearate

Function: Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

Zingiber Officinale (Ginger) Root Extract

Other name: Zingiber Officinale Root Extract; Ginger Root Extract

Function: Masking, Perfuming, Fragrance, Skin Conditioning, Tonic

1. Definition Zingiber Officinale (Ginger) Root Extract:

Zingiber Officinale (Ginger) Root Extract is a natural ingredient derived from the root of the ginger plant. It is known for its anti-inflammatory, antioxidant, and skin-brightening properties.

2. Use:

Ginger root extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and inflammation, and improve overall skin tone. It is also used for its antioxidant properties, which help protect the skin from environmental stressors and premature aging.

3. Usage Zingiber Officinale (Ginger) Root Extract:

Ginger root extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effect. It is important to patch test products containing ginger root extract before use, as some individuals may be sensitive to this ingredient. Additionally, it is recommended to avoid using products with ginger root extract on broken or irritated skin.

4. References:

- Lee, S. H., Cekanova, M., & Baek, S. J. (2008). Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Molecular Carcinogenesis, 47(3), 197-208.

- Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food and Chemical Toxicology, 46(2), 409-420.

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, S. M. (2011). Antioxidant and anti-inflammatory activities of barettin. Food and Chemical Toxicology, 49(9), 2054-2059.