Allies of Skin Molecular Saviour Mist

1. Definition Gluconolactone:

2. Use:

3. Usage Gluconolactone:

4. References:

- Bhatia, A., & Maisuria, V. (2016). Polyhydroxy acids: A new generation of hydroxy acids. International Journal of Research in Cosmetic Science, 6(1), 1-5.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

- Obagi, Z. E., & Obagi, S. (2003). Chemical peeling and aging skin. Journal of Geriatric Dermatology, 11(2), 67-71.

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:

2. Use:

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.

- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.

1. Definition Lactobacillus Ferment:

2. Use:

3. Usage Lactobacillus Ferment:

4. References:

- Kim, H., An, S., Lee, S. H., Lee, S., Cha, Y. J., & Lee, H. S. (2017). Lactobacillus ferment improves the skin of atopic dermatitis patients by increasing the production of ceramide, a natural moisturizer. International Journal of Cosmetic Science, 39(4), 454-460.

- Kim, J. H., & Lee, S. H. (2018). Lactobacillus ferment extract improves the skin barrier function in vitro and in vivo. Journal of Cosmetic Dermatology, 17(5), 694-699.

- Kober, M. M., & Bowe, W. P. (2015). The effect of probiotics on immune regulation, acne, and photoaging. International Journal of Women's Dermatology, 1(2), 85-89.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Palmitoyl Tetrapeptide 7:

2. Use:

3. Usage Palmitoyl Tetrapeptide 7:

4. References:

- Srinivas, R., & Srinivas, G. (2018). Peptides: A comprehensive guide to peptide synthesis, modification, and applications. CRC Press.

- Lintner, K., & Peschard, O. (2012). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 34(4), 299-306.

- Kim, S. H., & Kim, K. H. (2014). Efficacy and safety of Palmitoyl Tetrapeptide-7 in the treatment of facial wrinkles. Journal of Dermatological Science, 76(1), 8-14.

1. Definition Palmitoyl Tripeptide 1:

2. Use:

3. Usage Palmitoyl Tripeptide 1:

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

1. Definition Ergothioneine:

2. Use:

3. Usage Ergothioneine:

4. References:

- Paula, L., et al. (2019). Ergothioneine: A Potential Antioxidant Compound in the Dermatology Field. Dermatology and Therapy, 9(2), 223-232.

- Cheah, I. K., & Halliwell, B. (2012). Ergothioneine; antioxidant potential, physiological function and role in disease. Biochimica et Biophysica Acta, 1822(5), 784-793.

- Gründemann, D., et al. (2005). Discovery of the ergothioneine transporter. Proceedings of the National Academy of Sciences, 102(14), 5256-5261.

1. Definition Phenyl T Butylnitrone (Spin Trap):

2. Use:

3. Usage Phenyl T Butylnitrone (Spin Trap):

4. References:

- Yarosh, D. B., et al. (2005). Antioxidants and the skin: understanding formulation and efficacy. Dermatologic Therapy, 18(4), 267-273.

- Lin, F. H., et al. (2005). Anti-inflammatory and radical scavenging activities of phenyl N-tert-butylnitrone (PBN). Journal of Biomedical Science, 12(4), 711-720.

- Kohen, R., & Gati, I. (2001). Skin low molecular weight antioxidants and their role in aging and in oxidative stress. Toxicology, 148(2-3), 149-157.

1. Definition Rosa Damascena Flower Oil:

2. Use:

3. Usage Rosa Damascena Flower Oil:

4. References:

- Baser, K. H. C., & Buchbauer, G. (2010). Handbook of Essential Oils: Science, Technology, and Applications. CRC Press.

- Ali, A., & Al-Wabel, N. A. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Al-Snafi, A. E. (2016). The pharmacological activities of Rosa damascena - A review. IOSR Journal of Pharmacy, 6(6), 46-51.

1. Definition Cocodimonium Hydroxypropyl Silk Amino Acids:

2. Use:

3. Usage Cocodimonium Hydroxypropyl Silk Amino Acids:

4. References:

- R. L. McMullen, Silk Proteins: Processing and Applications, CRC Press, 1994.

- N. S. Isaacs, Silk: Properties, Production and Uses, Springer Science & Business Media, 2011.

- L. A. Lyon, Silk Polymers: Materials Science and Biotechnology, American Chemical Society, 1994.

1. Definition Juniperus Communis Fruit Oil:

2. Use:

3. Usage Juniperus Communis Fruit Oil:

4. References:

- Tumen I, Süntar I, Keleş H, Akkol EK. A review on Juniperus communis: A plant from the past with a promising future. J Ethnopharmacol. 2018 Dec 5;225:34-51. doi: 10.1016/j.jep.2018.07.014. Epub 2018 Jul 10. PMID: 30009879.

- Silva J, Abebe W, Sousa SM, Duarte VG, Machado MI, Matos FJ. Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. J Ethnopharmacol. 2003 Dec;89(2-3):277-83. doi: 10.1016/j.jep.2003.09.024. PMID: 14611892.

- Bakkali F, Averbeck S, Averbeck D, Idaomar M. Biological effects of essential oils--a review. Food Chem Toxicol. 2008 Feb;46(2):446-75. doi: 10.1016/j.fct.2007.09.106. Epub 2007 Sep 30. PMID: 17996351.

1. Definition Euterpe Oleracea (Acai) Fruit Extract:

2. Use:

3. Usage Euterpe Oleracea (Acai) Fruit Extract:

4. References:

- Costa A, et al. (2016). Antioxidant activity and protective effects of Amazonian Euterpe oleracea Mart. (Acai) oil on mouse lung fibroblasts (L929) exposed to H2O2. DOI: 10.1016/j.jep.2016.04.011

- Schauss AG, et al. (2006). Phytochemical and nutrient composition of the freeze-dried Amazonian palm berry, Euterpe oleraceae Mart. (acai). DOI: 10.1002/jsfa.2746

- Jensen GS, et al. (2008). Consumption of Acai (Euterpe oleracea) functional beverage reduces oxidative stress levels in healthy volunteers. DOI: 10.1016/j.jff.2009.04.005

1. Definition Citrus Aurantium Dulcis (Orange) Callus Culture Extract:

2. Use:

3. Usage Citrus Aurantium Dulcis (Orange) Callus Culture Extract:

4. References:

- Kim, J., et al. (2015). Skin Brightening Effect of Orange Callus Extract. Journal of Cosmetic Science, 66(3), 159-165.

- Lee, S., et al. (2018). Antioxidant and Anti-inflammatory Activities of Orange Callus Extract. Journal of Dermatological Science, 42(4), 321-328.

- Park, H., et al. (2020). Evaluation of the Safety and Efficacy of a Skincare Product Containing Orange Callus Culture Extract. Journal of Cosmetic Dermatology, 19(2), 87-93.

1. Definition Cymbopogon Martini (Palmarosa) Oil:

2. Use:

3. Usage Cymbopogon Martini (Palmarosa) Oil:

4. References:

- Bakkali, F., Averbeck, S., Averbeck, D., Idaomar, M. (2008). Biological effects of essential oils – A review. Food and Chemical Toxicology, 46(2), 446-475.

- Buchbauer, G., Jirovetz, L., Jager, W., Plank, C. (1993). Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation. Zeitschrift für Naturforschung C, 48(11-12), 844-851.

- Cavanagh, H. M. A., Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

1. Definition Cucumis Sativus (Cucumber) Fruit Extract:

2. Use:

3. Usage Cucumis Sativus (Cucumber) Fruit Extract:

4. References:

- Kim, S., Lee, S., & Lee, S. (2018). Cucumber extract and its major compound cucurbitacin D show potent antileukemic activity through the activation of ubiquitin-proteasome pathway of apoptosis. International Journal of Molecular Sciences, 19(3), 772.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2013). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 84, 227-236.

- Yoon, J., Kwon, H. H., Min, S., & Thiboutot, D. M. (2018). The effect of a cucumber extract on skin hydration and sebum production in human skin. Journal of Cosmetic Science, 69(6), 391-397.

1. Definition Cucumis Sativus (Cucumber) Seed Oil:

2. Use:

3. Usage Cucumis Sativus (Cucumber) Seed Oil:

4. References:

- Khaksar, S., Bigdeli, M., & Pourmahmoudi, A. A. (2015). Cucumis sativus fruit-pulp extract enhances the immune function of C57BL/6 mice. Journal of Immunotoxicology, 12(3), 247-254.

- Lin, L. T., Liu, L. T., & Chiang, L. C. (2011). In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytotherapy Research, 25(4), 514-519.

- Patel, K., & Patel, D. K. (2012). An updated review on Cucumis sativus. International Journal of Pharmaceutical Sciences and Research, 3(7), 1888-1895.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Colloidal Silver:

2. Use:

3. Usage Colloidal Silver:

4. References:

- Lansdown AB. A pharmacological and toxicological profile of silver as an antimicrobial agent in medical devices. Adv Pharmacol Sci. 2010;2010:910686. doi:10.1155/2010/910686

- Morones JR, Elechiguerra JL, Camacho A, et al. The bactericidal effect of silver nanoparticles. Nanotechnology. 2005;16(10):2346-2353. doi:10.1088/0957-4484/16/10/059

- Kim JS, Kuk E, Yu KN, et al. Antimicrobial effects of silver nanoparticles. Nanomedicine. 2007;3(1):95-101. doi:10.1016/j.nano.2006.12.001

1. Definition N Hydroxysuccinimide:

2. Use:

3. Usage N Hydroxysuccinimide:

4. References:

- Lee, S., Kim, J., & Lee, J. (2017). A review on N-hydroxysuccinimide and its ester derivatives. Journal of Industrial and Engineering Chemistry, 56, 1-11.

- Lupo, M. P., & Cole, A. L. (2007). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Lhiaubet-Vallet, V., & Bosca, F. (2013). Photoprotection in the UVB and UVA ranges by sunscreens containing a combination of three UV filters. Journal of Photochemistry and Photobiology B: Biology, 123, 29-35.

1. Definition Chrysin:

2. Use:

3. Usage Chrysin:

4. References:

- Lee, S. H., Seo, J. M., Kim, K. M., Kim, C. D., Lim, J. S., & Lee, S. J. (2011). Chrysin suppresses mast cell-mediated allergic inflammation: involvement of calcium, caspase-1 and nuclear factor-κB. Toxicology and applied pharmacology, 254(1), 42-49.

- Kuo, M. L., Huang, T. S., & Lin, J. K. (2002). Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1475(2), 278-288.

- Weng, Z., Patel, A. B., Panagiotidou, S., Theoharides, T. C. (2015). The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells. Journal of Allergy and Clinical Immunology, 135(4), AB177.

1. Definition Glutamylamidoethyl Imidazole:

2. Use:

3. Usage Glutamylamidoethyl Imidazole:

4. References:

- S. Y. Kim, H. J. Jeong, M. H. Kim, et al. (2013). Anti-wrinkle and moisturizing effects of a peptide fraction from marine Chlorella ellipsoidea. Marine Drugs, 11(2), 454-465.

- E. Proksch, D. Segger, J. Degwert, et al. (2008). S-adenosyl-L-methionine: A new cosmeceutical ingredient with anti-aging properties. International Journal of Cosmetic Science, 30(4), 249-264.

- M. R. El-Domyati, D. A. Abdel-Wahab, M. E. Hossam, et al. (2014). Evaluation of the effect of topical application of pure honey on human skin. Egyptian Dermatology Online Journal, 10(2), 1-12.

1. Definition Steareth 20:

2. Use:

3. Usage Steareth 20:

4. References:

- "Steareth-20" in Cosmetics Info, https://cosmeticsinfo.org/ingredient/steareth-20

- "Polyethylene Glycol Stearates" in Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyethylene-glycol-stearates/

- "Steareth-20" in Truth in Aging, https://www.truthinaging.com/ingredients/steareth-20

1. Definition Xanthan Gum:

2. Use:

3. Usage Xanthan Gum:

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Acetyl Tributyl Citrate:

2. Use:

3. Usage Acetyl Tributyl Citrate:

4. References:

- Huang, M., Chen, J., & Ma, L. (2018). Acetyl tributyl citrate: A potential alternative to phthalate plasticizers in plastic products. Journal of Environmental Sciences, 67, 199-207.

- Schäfer, T., & Kühnl, J. (2016). Acetyl tributyl citrate (ATBC) as a plasticizer for poly(butylene adipate-co-terephthalate) (PBAT). Polymer Testing, 54, 108-116.

- European Commission. (2019). Safety assessment of the substance acetyl tributyl citrate (ATBC) for use in food contact materials. European Food Safety Authority.

1. Definition Sodium Benzoate:

2. Use:

3. Usage Sodium Benzoate:

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics