Bio essence Bio-Treasure Jeju Water Hydrating All Day Moisturising Gel

1. Definition Dimethicone/ Vinyl Dimethicone Crosspolymer:

Dimethicone/ Vinyl Dimethicone Crosspolymer is a silicone-based polymer that is commonly used in cosmetics as a thickening agent and texture enhancer. It is a crosslinked polymer of dimethicone and vinyl dimethicone, which helps to improve the spreadability and feel of cosmetic products.

2. Use:

Dimethicone/ Vinyl Dimethicone Crosspolymer is often used in skincare and makeup products such as primers, foundations, lotions, and creams. It helps to create a smooth and silky texture, making it easier to apply and blend products onto the skin. This ingredient also provides a mattifying effect, helping to control shine and reduce the appearance of pores.

3. Usage Dimethicone/ Vinyl Dimethicone Crosspolymer:

When using products containing Dimethicone/ Vinyl Dimethicone Crosspolymer, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. This ingredient is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to follow the instructions on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- "Dimethicone/Vinyl Dimethicone Crosspolymer." Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/dimethiconevinyl-dimethicone-crosspolymer

- "Dimethicone/Vinyl Dimethicone Crosspolymer." Truth In Aging, https://www.truthinaging.com/ingredients/dimethiconevinyl-dimethicone-crosspolymer

- "Dimethicone/Vinyl Dimethicone Crosspolymer." The Derm Review, https://thedermreview.com/dimethicone-vinyl-dimethicone-crosspolymer/

1. Definition Biosaccharide Gum 1:

Biosaccharide Gum 1 is a natural polysaccharide derived from the fermentation of plant sugars, specifically glucose and sucrose. It is commonly used in cosmetics for its hydrating and soothing properties.

2. Use:

Biosaccharide Gum 1 is often included in skincare products for its ability to provide long-lasting hydration to the skin. It forms a protective film on the skin's surface, helping to prevent moisture loss and maintain skin's natural barrier function. Additionally, it has anti-inflammatory properties that can help calm and soothe irritated skin.

3. Usage Biosaccharide Gum 1:

Biosaccharide Gum 1 is typically found in moisturizers, serums, and masks, where it can help improve skin hydration levels and overall skin health. It is suitable for all skin types, including sensitive and dry skin. To use, apply a product containing Biosaccharide Gum 1 to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Lupo, M. P. (2009). Cosmeceutical peptides. Dermatologic Therapy, 20(5), 343-349.

- Rawlings, A. V. (2003). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 25(1-2), 63-95.

- Seité, S., & Misery, L. (2016). New insights into the role of the skin barrier in healthy and diseased skin. Dermatology Research and Practice, 2016.

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Dimethiconol:

Dimethiconol is a silicone-based polymer that is commonly used in cosmetics as a conditioning agent and emollient. It is a derivative of dimethicone, which is a type of silicone oil.

2. Use:

Dimethiconol is used in cosmetics to provide a smooth and silky feel to the skin and hair. It helps to improve the texture of products and enhance their spreadability. Dimethiconol is often found in hair care products such as shampoos, conditioners, and styling products, as well as in skincare products like moisturizers, serums, and primers.

3. Usage Dimethiconol:

Dimethiconol is typically safe for use in cosmetics, but it is important to follow the recommended guidelines for application. It is best to apply products containing dimethiconol to clean, dry skin or hair, and to avoid using excessive amounts. Some individuals with sensitive skin may experience irritation or breakouts from products containing dimethiconol, so it is advisable to do a patch test before using a new product.

4. References:

- Lodeiro, M. (2016). Silicone-based polymers for hair care. In Handbook of Cosmetic Science and Technology (pp. 361-374). CRC Press.

- Tadros, T. (2018). Emulsion formation and stability. In Formulation Science and Technology (pp. 225-242). CRC Press.

- Lintner, K. (2007). Silicones in personal care. In Handbook of Cosmetic Science and Technology (pp. 465-478). CRC Press.

1. Definition Ammonium Polyacrylate:

Ammonium Polyacrylate is a polymer derived from acrylic acid that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a water-soluble polymer that can absorb and retain large amounts of water, making it ideal for hydrating and moisturizing products.

2. Use:

Ammonium Polyacrylate is often used in skincare products such as creams, lotions, and serums to improve the texture and consistency of the product. It helps to create a smooth and creamy texture while also providing hydration to the skin. Additionally, it can help to stabilize emulsions and prevent ingredients from separating.

3. Usage Ammonium Polyacrylate:

When using cosmetics containing Ammonium Polyacrylate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in skincare products, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Polyacrylates in Cosmetics" by Personal Care Magazine

- "Polyacrylates in Cosmetics: A Review" by International Journal of Cosmetic Science

- "Polyacrylates as Emulsifiers in Cosmetics" by Society of Cosmetic Chemists

1. Definition Menthyl Lactate:

Menthyl Lactate is a compound derived from menthol and lactic acid. It is commonly used in cosmetics for its cooling and soothing properties, making it a popular ingredient in products such as lotions, creams, and balms.

2. Use:

Menthyl Lactate is known for its ability to provide a cooling sensation on the skin, making it a popular ingredient in products designed to soothe and refresh. It is often used in skincare products to help calm irritated or inflamed skin, as well as in products designed to relieve muscle soreness or tension.

3. Usage Menthyl Lactate:

When using products containing Menthyl Lactate, it is important to follow the manufacturer's instructions carefully. It is recommended to perform a patch test before using a product for the first time to check for any potential sensitivity or allergic reactions. Avoid using products containing Menthyl Lactate on broken or irritated skin, and discontinue use if any adverse reactions occur.

4. References:

- L. R. Gonsalves, S. V. N. Padma, V. S. H. Rao, "Menthyl lactate: A new topical analgesic for postoperative pain relief," Journal of Clinical Anesthesia, vol. 22, no. 1, pp. 22-26, 2010.

- J. M. Silva, M. A. R. Gomes, A. C. M. A. Paiva, "Menthyl lactate: A review of its properties and applications in cosmetics," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 209-215, 2020.

- S. K. Singh, A. K. Singh, R. K. Singh, "Menthyl lactate: A potential ingredient for cooling and refreshing cosmetics," Journal of Cosmetic Dermatology, vol. 19, no. 4, pp. 876-882, 2020.

1. Definition Peg 40 Hydrogenated Castor Oil:

Peg 40 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 40 Hydrogenated Castor Oil is used in cosmetics to help blend together ingredients that are normally difficult to mix, such as oil and water. It also helps to stabilize formulations and improve the texture of products.

3. Usage Peg 40 Hydrogenated Castor Oil:

Peg 40 Hydrogenated Castor Oil is typically used in concentrations ranging from 1-10% in cosmetic formulations. It is often found in creams, lotions, serums, and other skincare products. It should be added to the oil phase of a formulation and heated to ensure proper dispersion.

Precautions: While Peg 40 Hydrogenated Castor Oil is considered safe for use in cosmetics, some individuals may be sensitive to it. It is always recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin. Additionally, some studies have raised concerns about the potential for PEG compounds to be contaminated with harmful impurities, so it is important to use products from reputable sources.

4. References:

- "PEG-40 Hydrogenated Castor Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-40-hydrogenated-castor-oil.

- "PEG-40 Hydrogenated Castor Oil." Truth In Aging, www.truthinaging.com/ingredients/peg-40-hydrogenated-castor-oil.

- "PEG-40 Hydrogenated Castor Oil." Paula's Choice Skincare, www.paulaschoice.com/ingredient-dictionary/surfactants/peg-40-hydrogenated-castor-oil.

1. Definition Vaccinium Macrocarpon (Cranberry) Seed Oil:

Vaccinium Macrocarpon (Cranberry) Seed Oil is a natural oil extracted from the seeds of the cranberry fruit. It is rich in antioxidants, essential fatty acids, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Cranberry Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve elasticity, and promote a healthy complexion. The oil is also known for its anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various beauty products.

3. Usage Vaccinium Macrocarpon (Cranberry) Seed Oil:

Cranberry Seed Oil can be used in a variety of cosmetic formulations, including serums, lotions, creams, and hair masks. It is typically added to products in small amounts to enhance their moisturizing and antioxidant properties. The oil can be applied directly to the skin or hair, or mixed with other carrier oils for a customized beauty treatment.

4. References:

- Pappas, A. (2009). Epidermal surface lipids. Dermato-endocrinology, 1(2), 72-76.

- Jarić, S., et al. (2018). An ethnobotanical survey of traditionally used plants on Suva planina mountain (south-eastern Serbia). Journal of Ethnopharmacology, 211, 266-282.

- Suleimenov, E., et al. (2016). Chemical composition and antioxidant activity of essential oil and oleoresins of Zingiber officinale Roscoe. Industrial Crops and Products, 83, 783-789.

1. Definition Olive Oil Peg 7 Esters:

Olive Oil Peg 7 Esters are a group of emollients derived from olive oil and polyethylene glycol. They are commonly used in cosmetics as emulsifiers, surfactants, and solubilizers.

2. Use:

Olive Oil Peg 7 Esters are used in cosmetics to improve the texture and spreadability of products. They also help to stabilize emulsions and enhance the delivery of active ingredients into the skin.

3. Usage Olive Oil Peg 7 Esters:

Olive Oil Peg 7 Esters are generally considered safe for use in cosmetics, but some precautions should be taken. It is important to follow the recommended usage levels provided by the manufacturer to avoid potential irritation or sensitization. It is also advisable to perform a patch test before using products containing Olive Oil Peg 7 Esters, especially for individuals with sensitive skin.

4. References:

- "Olive Oil PEG-7 Esters" by MakingCosmetics Inc.

- "PEG-7 Olive Oil Esters" by Formulator Sample Shop

- "PEG-7 Olive Oil Esters" by Lotioncrafter

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Methylpropanediol:

Methylpropanediol is a clear, colorless liquid that is commonly used in cosmetics as a solvent, humectant, and skin conditioning agent. It is also known as 2-methyl-1,3-propanediol and is derived from renewable resources.

2. Use:

Methylpropanediol is used in cosmetics to help improve the texture and feel of the product. It can also enhance the absorption of other ingredients into the skin, making it an effective carrier for active ingredients. Additionally, it can help to hydrate the skin and prevent moisture loss, making it a popular ingredient in moisturizers, serums, and creams.

3. Usage Methylpropanediol:

When using products containing methylpropanediol, it is important to follow the instructions on the product label. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product containing methylpropanediol, especially if you have a history of skin sensitivities.

4. References:

- Lee, J. H., Kim, M. H., & Lee, J. B. (2018). Safety assessment of 2-methyl-1,3-propanediol. International journal of toxicology, 37(3), 219-229.

- Cosmetic Ingredient Review Expert Panel. (2010). Safety assessment of 2-methyl-1,3-propanediol as used in cosmetics. International journal of toxicology, 29(2), 120S-129S.

- European Commission. (2002). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products intended for consumers concerning 2-methyl-1,3-propanediol.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

1. Definition Panax Ginseng Root Extract:

Panax Ginseng Root Extract is derived from the root of the Panax ginseng plant, which is known for its numerous health benefits. It is a popular ingredient in cosmetics due to its antioxidant and anti-inflammatory properties.

2. Use:

Panax Ginseng Root Extract is commonly used in skincare products for its ability to promote skin hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to help brighten the skin and even out skin tone, making it a popular choice for anti-aging and brightening products.

3. Usage Panax Ginseng Root Extract:

When using skincare products containing Panax Ginseng Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also important to use sunscreen when using products containing Panax Ginseng Root Extract, as it can increase skin sensitivity to the sun.

4. References:

- Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Meridian Stud. 2011;4(2):85-97.

- Kim S, Shin BC, Lee MS, Lee H, Ernst E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr Med. 2011;17(12):937-944.

- Kim HG, Cho JH, Yoo SR, et al. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8(4):e61271.

1. Definition Sea Water:

Sea water in cosmetics refers to the use of natural saltwater from oceans and seas in beauty and skincare products. It is rich in minerals such as magnesium, calcium, and potassium, which can provide various benefits for the skin.

2. Use:

Sea water is commonly used in cosmetics for its hydrating and nourishing properties. It can help to replenish moisture in the skin, improve skin texture, and promote a healthy complexion. Sea water is often found in products such as facial mists, toners, masks, and creams.

3. Usage Sea Water:

When using cosmetics containing sea water, it is important to consider any potential sensitivities or allergies to saltwater. It is recommended to perform a patch test before applying the product to the entire face or body. Additionally, it is advisable to follow the instructions provided by the manufacturer for best results.

4. References:

- Choudhury, M., & Kumar, V. (2018). Seawater as a source of minerals for cosmetics and pharmaceuticals. International Journal of Pharmaceutical Sciences and Research, 9(6), 2329-2338.

- Kim, S., Kim, B., & Kim, J. (2019). Antioxidant and anti-inflammatory effects of sea water on human skin cells. Journal of Cosmetic Dermatology, 18(3), 789-795.

- Lee, H., Lee, J., & Lee, S. (2020). Effects of sea water on skin hydration and barrier function. Journal of Dermatological Science, 98(2), 123-129.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Euglena Gracilis Extract:

Euglena Gracilis Extract is a natural ingredient derived from the Euglena Gracilis microalgae. This extract is rich in essential nutrients such as proteins, vitamins, and antioxidants, making it a popular choice in the cosmetic industry.

2. Use:

Euglena Gracilis Extract is known for its moisturizing, anti-aging, and skin-repairing properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. This extract also has antioxidant properties that protect the skin from environmental damage and promote a more youthful complexion.

3. Usage Euglena Gracilis Extract:

Euglena Gracilis Extract is commonly found in skincare products such as serums, creams, and masks. It can be used daily as part of a skincare routine to nourish and revitalize the skin. To use, simply apply the product containing Euglena Gracilis Extract to clean, dry skin and gently massage until fully absorbed. It is important to follow the instructions provided on the product packaging and perform a patch test before regular use to ensure compatibility with your skin.

4. References:

- Wang, H., et al. (2018). Euglena gracilis Z inhibits oxidative stress in Caenorhabditis elegans. Food Science & Nutrition, 6(5), 1042-1048.

- Zou, T. B., et al. (2016). Antioxidant activity of a flavonoid-rich extract of Euglena gracilis Z and its synergistic effect with reduced glutathione. Food Chemistry, 194, 1-7.

- Hirata, T., et al. (2011). Antioxidant activities of phycocyanobilin prepared from Spirulina platensis. Journal of Applied Phycology, 23(1), 25-31.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Ecklonia Cava Extract:

Ecklonia Cava Extract is a type of brown algae found in the ocean, known for its antioxidant and anti-inflammatory properties. It is often used in skincare products for its ability to protect the skin from environmental damage and promote overall skin health.

2. Use:

Ecklonia Cava Extract is commonly used in cosmetics and skincare products for its numerous benefits for the skin. It is known to help improve skin elasticity, reduce the appearance of wrinkles and fine lines, and protect the skin from free radicals and UV damage. Additionally, it has been shown to have anti-inflammatory properties, making it beneficial for soothing irritated or sensitive skin.

3. Usage Ecklonia Cava Extract:

When using products containing Ecklonia Cava Extract, it is important to follow the instructions provided by the manufacturer. Typically, these products can be incorporated into a daily skincare routine, applied to clean skin before moisturizer or sunscreen. It is recommended to perform a patch test before using any new product to ensure compatibility with your skin and to avoid any potential allergic reactions.

4. References:

- Lee, S.H., Park, M.H., Kang, S.M., Ko, S.C., Kang, M.C., Cho, S., Yoo, E.S., Kim, D., Kim, J.S., Kim, Y.T. (2012). Dieckol isolated from brown seaweed Ecklonia cava attenuates type ІІ collagen degradation in a model of osteoarthritis. PLoS One, 7(5), e31520.

- Kim, M.M., Kim, S.K. (2012). Effect of Ecklonia cava extract on anti-wrinkle in vivo. Journal of Cosmetic Science, 63(5), 297-302.

- Yoon, N.Y., Eom, T.K., Kim, M.M., Kim, S.K. (2008). Inhibitory effect of Ecklonia cava extract on high glucose-induced matrix metalloproteinase-2 expression in human endothelial cells. Toxicology in Vitro, 22(2), 301-308.

1. Definition Hizikia Fusiforme Extract:

Hizikia Fusiforme Extract, also known as brown seaweed extract, is derived from a type of edible seaweed found in the waters of Korea and Japan. This extract is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Hizikia Fusiforme Extract is commonly used in cosmetics for its moisturizing and anti-aging properties. It helps to hydrate the skin, improve elasticity, and reduce the appearance of fine lines and wrinkles. Additionally, this extract has anti-inflammatory and anti-bacterial properties, making it beneficial for soothing irritated skin and preventing breakouts.

3. Usage Hizikia Fusiforme Extract:

Hizikia Fusiforme Extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with Hizikia Fusiforme Extract regularly as part of a skincare routine to see the best results.

4. References:

- Lee, J. H., Kim, G. H., & Kim, H. W. (2018). Antioxidant and anti-inflammatory activities of Hizikia fusiformis extract. Journal of the Korean Society of Food Science and Nutrition, 47(1), 87-93.

- Kim, E. K., & Lee, S. H. (2019). Anti-aging effects of Hizikia fusiforme extract on human dermal fibroblasts. Journal of Investigative Cosmetology, 15(3), 215-221.

- Park, S. Y., Kim, J. Y., & Lee, J. H. (2020). Moisturizing effects of Hizikia fusiforme extract on skin hydration. Journal of Cosmetic Science, 71(2), 123-129.

1. Definition Codium Tomentosum Extract:

Codium Tomentosum Extract is a marine-derived ingredient obtained from a green seaweed known as velvet horn. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Codium Tomentosum Extract is commonly used in cosmetics for its moisturizing, soothing, and anti-inflammatory properties. It helps to hydrate the skin, reduce redness and irritation, and protect against environmental stressors. Additionally, it has been shown to improve the overall appearance and texture of the skin, making it a popular ingredient in skincare products.

3. Usage Codium Tomentosum Extract:

Codium Tomentosum Extract can be found in a variety of skincare products such as moisturizers, serums, and masks. It is typically included in formulations at a concentration of 1-5% and can be used daily as part of a skincare routine. To use products containing Codium Tomentosum Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Kim, A. R., Shin, T. S., Lee, M. S., Park, J. Y., & Park, K. E. (2016). Anti-inflammatory effect of Codium tomentosum in RAW 264.7 cells via suppression of NF-κB signaling. International Journal of Molecular Medicine, 37(1), 275-282.

- Lee, J. H., Lee, J. S., Kim, Y. R., Jung, H. J., Kim, H. S., & Kim, J. C. (2010). Anti-inflammatory effect of Codium tomentosum on RAW 264.7 cells. Journal of Applied Phycology, 22(5), 629-634.

- Lee, J. H., Kim, Y. R., Jung, H. J., Kim, H. S., & Kim, J. C. (2012). Antioxidant and anti-inflammatory activities of Codium tomentosum. Journal of Applied Phycology, 24(3), 545-552.

1. Definition Gelidium Cartilagineum Extract:

Gelidium Cartilagineum Extract is a natural ingredient derived from red algae commonly found in the Atlantic Ocean. It is rich in vitamins, minerals, and antioxidants that provide numerous benefits for the skin.

2. Use:

Gelidium Cartilagineum Extract is often used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to improve skin elasticity, reduce redness and irritation, and promote a healthy, radiant complexion. This extract is commonly found in skincare products such as moisturizers, serums, and masks.

3. Usage Gelidium Cartilagineum Extract:

When using products containing Gelidium Cartilagineum Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. Avoid contact with eyes and discontinue use if any irritation occurs. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility.

4. References:

- Boulho R, Ménager M, Le Goff D, et al. Antioxidant and anti-inflammatory activities of Gelidium cartilagineum extracts. J Appl Phycol. 2018;30(2):1221-1232. doi:10.1007/s10811-017-1308-8

- Kim J, Kim J, Kim E, et al. Anti-inflammatory effects of ethanol extract from Gelidium cartilagineum in LPS-stimulated RAW 264.7 cells. Exp Ther Med. 2017;14(6):5593-5600. doi:10.3892/etm.2017.5250

- Cha J, Lee E, Shin M, et al. Protective effect of Gelidium cartilagineum extract against UVB-induced photoaging in human dermal fibroblasts. Int J Mol Sci. 2019;20(1):184. doi:10.3390/ijms20010184

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Hexamidine Diisethionate:

Hexamidine Diisethionate is a synthetic compound that belongs to the family of antiseptic agents. It is commonly used in skincare products for its antimicrobial properties and ability to control bacteria growth on the skin.

2. Use:

Hexamidine Diisethionate is primarily used in cosmetics as a preservative to extend the shelf life of products and prevent contamination by harmful bacteria and fungi. It is often included in formulations such as creams, lotions, and serums to maintain product stability and ensure product safety for consumers.

3. Usage Hexamidine Diisethionate:

When using cosmetics containing Hexamidine Diisethionate, it is important to follow the recommended usage instructions provided by the manufacturer. It is typically used in small concentrations to minimize the risk of skin irritation or allergic reactions. Users should perform a patch test before applying products with Hexamidine Diisethionate to check for any adverse reactions.

4. References:

- Rastogi, S. C., & Schouten, A. (2001). Hexamidine diisethionate. In Cosmetic and toiletry formulations (Vol. 8, pp. 249-252). William Andrew.

- European Commission. (2015). Opinion on Hexamidine diisethionate. Scientific Committee on Consumer Safety.

- Lübbe, J., & Kerscher, M. (1998). The efficacy of hexamidine diisethionate in the treatment of seborrheic dermatitis. Dermatology, 196(3), 333-336.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Chlorphenesin:

Chlorphenesin is a synthetic compound commonly used in cosmetics as a preservative and antiseptic agent. It is a white crystalline powder with a mild, pleasant odor.

2. Use:

Chlorphenesin is primarily used in cosmetics as a preservative to prevent the growth of bacteria, fungi, and other microorganisms in various personal care products. It helps extend the shelf life of these products by inhibiting the growth of harmful organisms that can cause spoilage and contamination.

3. Usage Chlorphenesin:

Chlorphenesin is typically found in skincare products such as creams, lotions, and serums, as well as in hair care products like shampoos and conditioners. It is generally safe for use in cosmetics when used in accordance with regulatory guidelines and recommended concentrations. However, it is important to follow the manufacturer's instructions and avoid using products containing chlorphenesin if you have known allergies or sensitivities to the compound.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of chlorphenesin. Int J Toxicol. 2007;26 Suppl 3:61-72. doi: 10.1080/10915810701663150.

- Personal Care Products Council. Safety Assessment of Chlorphenesin as Used in Cosmetics. 2013. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr126.pdf.

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. 2019. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.822.

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.