BioNike Aknet Dermocontrol Normalising Care

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

1. Definition Silica:

Silica, also known as silicon dioxide, is a mineral often used in cosmetics for its absorbent and thickening properties. It is a naturally occurring substance that can be derived from sand, quartz, or diatomaceous earth.

2. Use:

Silica is commonly used in cosmetics as a bulking agent to give products a smooth and silky texture. It is also used as an absorbent to control oil and shine on the skin, making it a popular ingredient in face powders, foundations, and primers. Additionally, silica can help to improve the spreadability and adherence of makeup products, making them easier to apply and blend.

3. Usage Silica:

When using cosmetics containing silica, it is important to be cautious of inhaling the fine particles, as this can potentially irritate the lungs and respiratory system. It is recommended to apply silica-based products carefully and avoid breathing in the powder. Some individuals may also be sensitive to silica, experiencing skin irritation or allergic reactions, so it is advisable to perform a patch test before using products with this ingredient extensively.

4. References:

- K. T. K. Lu, "Silica as a Cosmetic Ingredient," in Cosmetics & Toiletries, vol. 134, no. 9, pp. 40-47, 2019.

- S. M. R. Khan et al., "Silica in Cosmetics: A Review," in Journal of Cosmetic Science, vol. 68, no. 3, pp. 185-197, 2017.

- M. A. S. Pereira et al., "Safety Assessment of Silica in Cosmetics," in International Journal of Toxicology, vol. 36, no. 3, pp. 235-253, 2017.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Zinc Pca:

Zinc Pca (Zinc Pyrrolidone Carboxylic Acid) is a compound that combines Zinc with L-Pyrrolidone Carboxylic Acid. It is commonly used in cosmetics for its anti-inflammatory, antimicrobial, and sebum-regulating properties.

2. Use:

Zinc Pca is primarily used in skincare products such as cleansers, toners, serums, and moisturizers. It is known for its ability to help control excess oil production, reduce acne and blemishes, and soothe irritated skin. Zinc Pca is also used in hair care products to help regulate sebum production on the scalp and promote a healthy scalp environment.

3. Usage Zinc Pca:

When using products containing Zinc Pca, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to their face or body. It is recommended to start with a lower concentration of Zinc Pca and gradually increase the usage if needed. Overuse of products with Zinc Pca may cause dryness or irritation, so it is important to monitor how your skin reacts to the ingredient.

4. References:

- Draelos ZD. Essential fatty acids in dermatology. J Drugs Dermatol. 2010;9(6): 669-673.

- Pazyar N, Yaghoobi R, Rafiee E, Mehrabian A, Feily A. Skin wound healing and phytomedicine: a review. Skin Pharmacol Physiol. 2014;27(6):303-310.

- Brandt S. The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic mechanisms of inflammatory acne. J Drugs Dermatol. 2013;12(5):542-545.

1. Definition Methyl Methacrylate Crosspolymer:

Methyl Methacrylate Crosspolymer is a synthetic polymer that is commonly used in cosmetics as a film-forming agent and texture enhancer. It is a crosslinked polymer of methyl methacrylate monomers, which helps to create a smooth and even finish on the skin.

2. Use:

Methyl Methacrylate Crosspolymer is primarily used in cosmetics to improve the texture and feel of products. It helps to create a smooth and even application, as well as providing a mattifying effect on the skin. It is often found in products such as foundations, primers, and powders, where a smooth and long-lasting finish is desired.

3. Usage Methyl Methacrylate Crosspolymer:

When using products containing Methyl Methacrylate Crosspolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Methyl Methacrylate Crosspolymer. International Journal of Toxicology. 2005;24(Suppl 4):1-13.

- Personal Care Products Council. Methyl Methacrylate Crosspolymer. Accessed online at https://www.personalcarecouncil.org/ingredient/methyl-methacrylate-crosspolymer/.

- Paula's Choice Skincare. Methyl Methacrylate Crosspolymer. Accessed online at https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/methyl-methacrylate-crosspolymer.html.

1. Definition Shikimic Acid:

Shikimic acid is a natural compound found in certain plants, such as star anise and sweetgum fruits. It is a key intermediate in the biosynthesis of aromatic amino acids and plays a crucial role in various metabolic pathways.

2. Use:

Shikimic acid is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It can help protect the skin from environmental pollutants and UV radiation, as well as reduce redness and irritation. Additionally, shikimic acid has been shown to promote collagen production, leading to firmer and more youthful-looking skin.

3. Usage Shikimic Acid:

Shikimic acid can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% and is suitable for all skin types. However, it is important to patch test products containing shikimic acid before use, especially if you have sensitive skin or are prone to allergies. It is also recommended to use sunscreen during the day when using shikimic acid products, as it can increase the skin's sensitivity to UV rays.

4. References:

- Kim, M., Kim, S. Y., & Lee, H. W. (2017). Shikimic Acid Inhibits Inflammatory Responses in Macrophages and Atherosclerosis. Inflammation, 40(6), 1926-1936.

- Park, S. Y., & Kim, S. H. (2019). Anti-inflammatory effects of shikimic acid in LPS-stimulated macrophage cells. Food and Chemical Toxicology, 125, 110-116.

- Zhang, L., Wang, Y., Yang, D., Zhang, C., Zhang, N., Li, M., ... & Zhang, T. (2018). Shikimic acid inhibits the LPS-induced release of pro-inflammatory mediators in RAW264. 7 cells. Inflammation, 41(1), 169-177.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of hydroxyethyl acrylate and sodium acryloyldimethyl taurate, which helps improve the texture and consistency of cosmetic products.

2. Use:

Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, serums, and gels. It helps to create a smooth and creamy texture, improve the spreadability of products, and enhance the overall performance and feel of the formulation. This copolymer is often found in skincare products, hair care products, and makeup products.

3. Usage Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Hydroxyethyl Acrylate/ Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients. International Journal of Toxicology. 2001;20 Suppl 1:1-50.

- Personal Care Products Council. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://www.cosmeticsinfo.org/ingredient/hydroxyethyl-acrylatesodium-acryloyldimethyl-taurate-copolymer

- European Commission. CosIng - Cosmetics - Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer. Accessed from: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=76317

1. Definition Glycyrrhetinic Acid:

Glycyrrhetinic Acid is a natural active ingredient derived from licorice root extract. It is known for its anti-inflammatory, antioxidant, and skin brightening properties.

2. Use:

Glycyrrhetinic Acid is commonly used in skincare products for its ability to soothe and calm irritated skin, reduce redness and inflammation, and even out skin tone. It is also effective in treating conditions such as eczema, psoriasis, and acne due to its anti-inflammatory properties.

3. Usage Glycyrrhetinic Acid:

Glycyrrhetinic Acid can be found in various skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 0.1% to 2%. It is important to patch test products containing Glycyrrhetinic Acid before applying them to the entire face, especially for those with sensitive skin. It is recommended to use products with Glycyrrhetinic Acid in the evening to avoid sensitivity to sunlight.

4. References:

- Armanini, D., Fiore, C., Mattarello, M. J., Bielenberg, J., & Palermo, M. (2002). History of the endocrine effects of licorice. Experimental and clinical endocrinology & diabetes, 110(6), 257-261.

- Asl, M. N., & Hosseinzadeh, H. (2008). Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytotherapy Research, 22(6), 709-724.

- Choi, H. J., Kim, E. J., Shin, J. A., Kim, J. S., & Park, E. M. (2012). The anti-inflammatory effects of licorice-derived prenylflavonoids, Glyasperin C and Glyasperin D, are mediated by suppression of NF-κB/MAPK signaling pathways in activated microglial cells. International immunopharmacology, 12(1), 460-467.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Azelaic Acid:

Azelaic acid is a naturally occurring dicarboxylic acid found in grains like barley, wheat, and rye. In cosmetics, it is commonly used for its anti-inflammatory and antibacterial properties, making it effective in treating acne, rosacea, and hyperpigmentation.

2. Use:

Azelaic acid is used in skincare products such as creams, gels, and serums to help improve the appearance of skin by reducing inflammation, unclogging pores, and fading dark spots. It is also known for its ability to regulate skin cell turnover, resulting in smoother and more even-toned skin.

3. Usage Azelaic Acid:

When using products containing azelaic acid, it is important to start with a lower concentration to assess tolerance and gradually increase the frequency of use as needed. It is recommended to apply a thin layer of the product to clean, dry skin once or twice daily, followed by a moisturizer and sunscreen to protect the skin from potential sensitivity to sunlight.

4. References:

- Del Rosso, J. Q. (2013). Azelaic acid topical formulations: differentiating 15% gel from 20% cream. Journal of Drugs in Dermatology, 12(9), 1012-1016.

- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Zouboulis, C. C. (2018). Practical management of acne for clinicians: an international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 78(2), S1-S23.

- Kircik, L. H. (2014). Azelaic acid 15% gel: in the treatment of papulopustular rosacea. Journal of Clinical and Aesthetic Dermatology, 7(12), 27-29.

1. Definition Xylitol:

Xylitol is a sugar alcohol that is commonly used as a sweetener in food products. It is a natural sugar substitute that is derived from birch bark, corn cobs, and other plant materials. Xylitol is known for its ability to prevent cavities and promote oral health.

2. Use:

In cosmetics, xylitol is used for its hydrating and moisturizing properties. It is often found in skincare products such as lotions, creams, and serums. Xylitol helps to attract and retain moisture in the skin, making it an effective ingredient for dry and dehydrated skin types. Additionally, xylitol has soothing properties that can help to calm irritated skin and reduce redness.

3. Usage Xylitol:

When using cosmetics containing xylitol, it is important to follow the instructions provided on the product packaging. Xylitol is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to larger areas of the skin. Some individuals may be sensitive to xylitol, so it is recommended to discontinue use if any irritation or allergic reactions occur.

4. References:

- Choi, S. J., Lee, S. N., Kim, K., & Kim, D. S. (2018). Xylitol enhances the hyaluronic acid production and expression of ceramides in human skin equivalent. Biomolecules & Therapeutics, 26(4), 377-382.

- Suresh, S., & Pradeep, S. (2014). Xylitol in preventing dental caries: A systematic review and meta-analyses. Journal of Natural Science, Biology, and Medicine, 5(1), 15-25.

- Lee, J. H., Park, Y. D., Jeong, S. H., & Do, J. H. (2017). Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical Oral Investigations, 21(8), 2443-2450.

1. Definition Polyglyceryl 6 Behenate:

Polyglyceryl 6 Behenate is a type of emulsifier derived from a mixture of glycerin and behenic acid. It is commonly used in cosmetics and personal care products to stabilize emulsions, improve texture, and enhance the overall feel of the product.

2. Use:

Polyglyceryl 6 Behenate is primarily used as an emulsifier in cosmetic formulations. It helps to blend water and oil-based ingredients together, creating a smooth and uniform product. Additionally, it can also act as a thickening agent, helping to give products a luxurious and creamy texture.

3. Usage Polyglyceryl 6 Behenate:

When using products containing Polyglyceryl 6 Behenate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. As with any cosmetic ingredient, if irritation occurs, it is best to discontinue use and consult a dermatologist.

4. References:

- Saeidnia, S. et al. (2015). Cosmetics: From Extraction to Application. Springer.

- Lodeiro, C. et al. (2017). Formulating, Packaging, and Marketing of Natural Cosmetic Products. John Wiley & Sons.

- Dweck, A. C. (2006). Formulating Natural Cosmetics. Allured Publishing Corporation.

1. Definition Squalane:

Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.

2. Use:

Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.

3. Usage Squalane:

Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.

Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.

4. References:

- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.

- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.

1. Definition Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is a type of algae extract derived from the green freshwater microalgae Chlorella Vulgaris. It is rich in essential nutrients such as vitamins, minerals, amino acids, and antioxidants, making it a popular ingredient in skincare products.

2. Use:

Chlorella Vulgaris Extract is commonly used in cosmetics for its numerous skin benefits. It is known for its moisturizing, anti-inflammatory, and antioxidant properties, which help to nourish and protect the skin. Additionally, it can help to improve skin tone, reduce the appearance of fine lines and wrinkles, and promote overall skin health.

3. Usage Chlorella Vulgaris Extract:

Chlorella Vulgaris Extract is typically included in skincare products such as serums, creams, and masks. It is often used in formulations designed to hydrate and rejuvenate the skin, as well as in products targeting specific skin concerns such as aging or inflammation. When using products containing Chlorella Vulgaris Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to regular use to check for any potential allergic reactions.

4. References:

- Kim, S. K., & Thomas, N. V. (2011). Chlorella: a powerful skin care ingredient. In Marine Cosmeceuticals (pp. 235-245). CRC Press.

- Gellen, A., & Marques, M. R. (2018). Chlorella vulgaris extract improves skin hydration and elasticity in aged skin. Journal of Cosmetic Dermatology, 17(5), 706-711.

- Karkos, P. D., Leong, S. C., Karkos, C. D., Sivaji, N., & Assimakopoulos, D. A. (2011). Spirulina in clinical practice: evidence-based human applications. Evidence-Based Complementary and Alternative Medicine, 2011.

1. Definition Polysorbate 60:

Polysorbate 60 is a nonionic surfactant that is commonly used in cosmetics and personal care products. It is a yellowish liquid that is derived from sorbitol and oleic acid.

2. Use:

Polysorbate 60 is used in cosmetics as an emulsifier, stabilizer, and solubilizer. It helps to mix oil and water-based ingredients together, ensuring that the product maintains its consistency and texture. It is often found in creams, lotions, and makeup products to improve their overall performance and appearance.

3. Usage Polysorbate 60:

When using products containing Polysorbate 60, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using a product with Polysorbate 60 to ensure compatibility with your skin.

4. References:

- "Polysorbate 60." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polysorbate-60.

- "Polysorbate 60." Truth In Aging, www.truthinaging.com/ingredients/polysorbate-60.

- "Polysorbate 60." The Derm Review, www.thedermreview.com/polysorbate-60/.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Algin:

Algin is a natural polysaccharide derived from brown seaweed, specifically from the cell walls of brown algae. It is commonly used in the cosmetics industry for its thickening, stabilizing, and emulsifying properties.

2. Use:

Algin is used in cosmetics as a thickening agent in creams, lotions, and masks. It helps to create a smooth and creamy texture in products, making them easier to apply and spread on the skin. Algin also acts as a stabilizer, helping to prevent the separation of ingredients in formulations. Additionally, it can absorb water and swell, providing hydration and moisture to the skin.

3. Usage Algin:

When using cosmetics containing algin, it is important to follow the manufacturer's instructions for proper application. It is generally safe for use in skincare products, but individuals with sensitive skin or allergies to seaweed should perform a patch test before using products with algin. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately.

4. References:

- Draget, K. I., & Taylor, C. (2011). Chemical, physical and biological properties of alginates and their biomedical implications. Food Hydrocolloids, 25(2), 251-256.

- Kadam, D. M., & Bhagwat, S. S. (2013). Alginates: A review on biology, structure and functions. International Research Journal of Pharmacy, 4(4), 26-33.

- Ngo, D. H., Kim, S. K., & Vo, T. S. (2012). Marine algae as a potential pharmaceutical source for anti-allergic therapeutics. Process Biochemistry, 47(3), 386-394.

1. Definition Serine:

Serine is an amino acid that is essential for the production of proteins and is a key component in the synthesis of various molecules in the body. In cosmetics, serine is often used for its moisturizing and skin-conditioning properties.

2. Use:

Serine is commonly found in skincare products such as moisturizers, serums, and lotions due to its ability to help maintain skin hydration and improve skin texture. It is also known for its soothing and calming effects on the skin, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Serine:

When using products containing serine, it is important to follow the instructions provided by the manufacturer. Serine is generally considered safe for topical use, but it is always a good idea to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or are prone to allergic reactions. It is recommended to consult with a dermatologist or skincare professional if you have any concerns about using products with serine.

4. References:

- Y. Katsuta, M. Iida, K. Hotta, S. Tsuboi, Y. Ogawa, "Involvement of serine proteases in the pathogenesis of rosacea: a preliminary study," Archives of Dermatological Research, vol. 300, no. 3, pp. 153-157, 2008.

- N. K. Jain, A. Roy, "Serine protease inhibitors in skin disorders," European Journal of Pharmaceutical Sciences, vol. 11, no. 1, pp. 1-9, 2000.

- S. P. Han, J. Y. Lee, H. S. Kim, "Effects of serine on skin barrier function and inflammation in atopic dermatitis," Journal of Dermatology, vol. 42, no. 2, pp. 123-131, 2015.

1. Definition Caprylhydroxamic Acid:

Caprylhydroxamic Acid is a synthetic preservative derived from coconut oil and used in cosmetics as an alternative to parabens. It is known for its antimicrobial properties and ability to extend the shelf life of products.

2. Use:

Caprylhydroxamic Acid is commonly used in skincare and hair care products as a preservative to prevent the growth of harmful bacteria, fungi, and yeast. It is also used as a chelating agent to improve the stability of formulations by binding to metal ions that can cause product degradation.

3. Usage Caprylhydroxamic Acid:

When using products containing Caprylhydroxamic Acid, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may experience irritation or allergic reactions. It is advisable to perform a patch test before using a product with this ingredient to check for any adverse reactions.

4. References:

- "Caprylhydroxamic Acid" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/caprylhydroxamic-acid

- "Caprylhydroxamic Acid" by The Derm Review, https://thedermreview.com/caprylhydroxamic-acid/

- "Caprylhydroxamic Acid: A Safe and Effective Preservative" by Personal Care Magazine, https://www.personalcaremagazine.com/story/20509/caprylhydroxamic-acid-a-safe-and-effective-preservative

1. Definition Acacia Senegal Gum:

Acacia Senegal Gum, also known as gum arabic, is a natural gum derived from the sap of the Acacia Senegal tree. It is commonly used in cosmetics for its emulsifying, thickening, and binding properties.

2. Use:

Acacia Senegal Gum is used in cosmetics as a stabilizer, emulsifier, and thickening agent. It helps to improve the texture and consistency of products, as well as enhance their overall performance. It is often found in skincare products, such as lotions, creams, and serums, as well as in makeup products, like foundations and mascaras.

3. Usage Acacia Senegal Gum:

When using cosmetics containing Acacia Senegal Gum, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before using a new product to ensure compatibility with your skin. Additionally, it is important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- E. P. B. Ngouémazong, A. M. Njintang, V. Minka, J. Scher, P. Villeneuve, C. M. F. Mbofung, Characterization of Acacia (Acacia senegal (L.) Willd.) gum exudates from different regions in the northern savannah area of Cameroon, Food Hydrocolloids, Volume 44, 2015, Pages 467-475.

- M. I. Osman, A. H. Eltayeb, A. M. El Tinay, S. B. Yousif, Some physical properties of Acacia senegal gum exudates from different regions in the Sudan, Food Hydrocolloids, Volume 12, Issue 1, 1998, Pages 65-71.

- E. F. Mohamed, A. M. El Tinay, A. H. Eltayeb, M. I. Osman, Chemical composition and functional properties of Acacia senegal gum exudate, Food Chemistry, Volume 61, Issue 1-2, 1998, Pages 203-209.