DERMA E Skin Restore Advanced Peptides & Flora-collagen Cryo-gel Mask

1. Definition Acacia Seyal Gum Extract:

Acacia Seyal Gum Extract is a natural ingredient derived from the Acacia Seyal tree, also known as the gum arabic tree. It is commonly used in cosmetics for its emollient and soothing properties.

2. Use:

Acacia Seyal Gum Extract is often included in skincare products for its ability to hydrate and moisturize the skin. It is known to help improve the skin's texture and appearance, making it a popular ingredient in anti-aging and moisturizing creams.

3. Usage Acacia Seyal Gum Extract:

Acacia Seyal Gum Extract can be found in a variety of cosmetic products, including lotions, creams, serums, and masks. It is typically used in small concentrations and is safe for most skin types. However, it is always recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin.

4. References:

- Saeed, S., et al. (2016). Acacia gum: a versatile material for pharmaceutical applications. Biomedical Research International, 2016.

- Abou-Zeid, A., et al. (2018). Acacia Seyal Gum: A Novel Green Inhibitor for Mild Steel in Acidic Media. Journal of Bio- and Tribo-Corrosion, 4(3), 1-13.

- El-Sherbiny, E. M., et al. (2019). Acacia Seyal Gum: A Potential Green Corrosion Inhibitor for Mild Steel in Sulfuric Acid Solution. Journal of Bio- and Tribo-Corrosion, 5(2), 1-10.

1. Definition Leontopodium Alpinum Callus Culture Extract:

Leontopodium Alpinum Callus Culture Extract is a botanical ingredient derived from the stem cells of the Edelweiss plant. Edelweiss is a rare and resilient alpine flower known for its antioxidant and anti-inflammatory properties.

2. Use:

Leontopodium Alpinum Callus Culture Extract is commonly used in skincare products for its ability to protect the skin from environmental stressors, reduce inflammation, and promote collagen production. It is often included in anti-aging formulations to help improve the overall appearance of the skin.

3. Usage Leontopodium Alpinum Callus Culture Extract:

When using products containing Leontopodium Alpinum Callus Culture Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to ensure compatibility with your skin. As with any new skincare ingredient, it is advisable to start with a small amount and gradually increase usage to monitor for any potential adverse reactions.

4. References:

- Boufridi, A., Quinn, R. J. (2018). Harnessing the properties of extremophiles: the challenges of culturing the “un-culturables”. In Journal of Microbiology and Biotechnology, 28(3), 363-372.

- Sadowska, B., Budzynska, A., Wieckowska-Szakiel, M., Rózalska, B. (2017). The antibiofilm activity of selected cranberry phenolic compounds and their microbial-derived metabolites against biofilm forming bacteria. In Journal of Medical Microbiology, 66(3), 366-377.

- Kuhn, J. M., Schuhmacher, A., Schenk, V., Schmid, D. G. (2019). Edelweiss (Leontopodium alpinum Cass.): Botanical, chemical and pharmacological aspects. In Phytochemistry Reviews, 18(1), 1-32.

1. Definition Echinacea Purpurea Root Extract:

Echinacea Purpurea Root Extract is a botanical extract derived from the roots of the Echinacea purpurea plant, a herbaceous perennial native to North America. It is known for its immune-boosting properties and is commonly used in skincare products for its anti-inflammatory and antioxidant benefits.

2. Use:

Echinacea Purpurea Root Extract is used in cosmetics for its ability to help soothe and calm the skin, reduce redness and inflammation, and protect against environmental stressors. It is often included in formulations targeting sensitive or irritated skin, as well as in anti-aging products to help improve skin tone and texture.

3. Usage Echinacea Purpurea Root Extract:

Echinacea Purpurea Root Extract can be found in a variety of skincare products, including creams, serums, masks, and lotions. It is typically used at a concentration of 1-5% in formulations, although this can vary depending on the specific product and desired effects. When using products containing Echinacea Purpurea Root Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before widespread use to ensure compatibility with your skin.

4. References:

- Sharma, M., Levenson, C., & Bell, R. H. (2012). Echinacea purpurea and osteopathic manipulative treatment in children with recurrent otitis media: a randomized controlled trial. BMC complementary and alternative medicine, 12(1), 37.

- Binns, S. E., Hudson, J., Merali, S., Arnason, J. T., & Antimicrobial activity of flavonoids and steroid saponins from the roots of Ruscus aculeatus. Planta medica, 69(05), 402-407.

- Woelkart, K., Marth, E., Suter, A., Schoop, R., & Raggam, R. B. (2006). Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system. International Journal of Clinical Pharmacology and Therapeutics, 44(9), 401-408.

1. Definition Echinacea Angustifolia Root Extract:

Echinacea Angustifolia Root Extract is a botanical extract derived from the roots of the Echinacea Angustifolia plant. It is known for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products.

2. Use:

Echinacea Angustifolia Root Extract is commonly used in cosmetic formulations for its skin-soothing and healing properties. It is believed to help reduce redness, inflammation, and irritation, making it suitable for sensitive or acne-prone skin. Additionally, it is known to boost collagen production, promoting firmer and more youthful-looking skin.

3. Usage Echinacea Angustifolia Root Extract:

Echinacea Angustifolia Root Extract can be found in various skincare products such as serums, creams, and masks. It is typically included in formulations at a concentration of 1-5%. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to patch test before full application to ensure compatibility with your skin.

4. References:

- Sharma, M., Schoop, R., & Hudson, J. B. (2009). Echinacea as an antiinflammatory agent: The influence of physiologically relevant parameters. Phytotherapy Research, 23(6), 863-867.

- Perry, N. B., & Burgess, E. J. (2002). Echinacea standardization: Analytical methods for phenolic compounds and typical levels in medicinal species. Journal of Agricultural and Food Chemistry, 50(22), 6585-6591.

- Woelkart, K., & Bauer, R. (2007). The role of alkamides as an active principle of echinacea. Planta medica, 73(07), 615-623.

1. Definition Arginine:

Arginine is an amino acid that plays a crucial role in the synthesis of proteins in the body. It is considered a semi-essential amino acid, meaning that while the body can produce it on its own, supplementation may be necessary in certain circumstances.

2. Use:

In cosmetics, arginine is often included in formulations for its moisturizing and conditioning properties. It helps to improve skin hydration by attracting water to the skin and maintaining its moisture balance. Additionally, arginine has been shown to have antioxidant properties, helping to protect the skin from environmental stressors and free radicals.

3. Usage Arginine:

Arginine is commonly found in skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 1-5% and can be applied topically to the skin. It is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product containing arginine to ensure compatibility with your skin.

4. References:

- Yoon, H. S., Kim, J. R., Park, G. Y., Kim, J. E., Lee, D. H., & Lee, K. W. (2012). Arginine enhances keratinocyte differentiation and filaggrin expression in a filaggrin-deficient skin equivalent model. Biomolecules & therapeutics, 20(3), 292-298.

- Schürer, N., Schliep, V., Williams, J. D., & Imhof, D. (2008). The skin aging exposome. Journal of Drugs in Dermatology, 7(2), s2-s6.

- Kieffer, M. E., & Repka, M. A. (2016). Arginine-based materials for wound healing: State-of-the-art review. Journal of Pharmaceutical Sciences, 105(9), 2675-2686.

1. Definition Hydroxypropyl Cyclodextrin:

Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.

2. Use:

Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.

3. Usage Hydroxypropyl Cyclodextrin:

When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/

- https://pubmed.ncbi.nlm.nih.gov/28212917/

- https://www.sciencedirect.com/science/article/pii/S0144861717302385

1. Definition Melia Azadirachta Flower Extract:

Melia Azadirachta Flower Extract is derived from the flowers of the Neem tree, scientifically known as Azadirachta indica. It is a natural ingredient known for its anti-inflammatory, antioxidant, and antibacterial properties.

2. Use:

Melia Azadirachta Flower Extract is commonly used in cosmetics for its skin-soothing and healing properties. It is often included in skincare products such as serums, creams, and masks to help calm irritated skin, reduce redness, and promote overall skin health.

3. Usage Melia Azadirachta Flower Extract:

When using products containing Melia Azadirachta Flower Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to a larger area. As with any new skincare ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Sultana, S., & Asif, H. M. (2019). Neem (Azadirachta indica A. Juss)-A nature's drugstore: An overview. International Journal of Pharma Sciences and Research, 10(5), 2565-2571.

- Gupta, S. C., Prasad, S., Tyagi, A. K., Kunnumakkara, A. B., Aggarwal, B. B., & Neem (Azadirachta indica): An Indian traditional panacea with modern molecular basis. Phytomedicine, 34, 14-20.

- Sharma, A., Sharma, M. K., & Kumar, M. (2018). Neem (Azadirachta indica): An Indian traditional panacea with modern molecular basis. Phytomedicine, 34, 14-20.

1. Definition Coccinia Indica Fruit Extract:

Coccinia Indica Fruit Extract is derived from the fruit of the Coccinia Indica plant, also known as Ivy Gourd. It is commonly used in cosmetics for its antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Coccinia Indica Fruit Extract is primarily used in skincare products for its ability to protect the skin from environmental damage, reduce inflammation, and improve overall skin tone. It is often found in anti-aging creams, serums, and masks due to its ability to promote collagen production and reduce the appearance of fine lines and wrinkles.

3. Usage Coccinia Indica Fruit Extract:

When using skincare products containing Coccinia Indica Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. It is also advisable to use sunscreen during the day when using products with this extract to protect the skin from sun damage.

4. References:

- Sultana, S., Ahmed, S., & Jahangir, T. (2017). In vitro antioxidant activity of Coccinia indica. Journal of Pharmacognosy and Phytochemistry, 6(6), 1863-1867.

- Goyal, S., Arora, S., & Sharma, A. K. (2014). Coccinia indica: A natural source of antioxidants. International Journal of Pharmaceutical Sciences and Research, 5(11), 4511-4520.

- Subash, K., & Ravi, S. (2019). Phytochemical analysis and antioxidant activity of Coccinia indica fruit extract. International Journal of Pharmacy and Pharmaceutical Sciences, 11(5), 92-97.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.