Dot & Key Age Defense Night Glow Serum

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract, also known as Moutan or Tree Peony Root Extract, is derived from the root of the Paeonia suffruticosa plant. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Root Extract is commonly used in cosmetics for its various skincare benefits. It is known to help improve skin texture, reduce redness and inflammation, and brighten the complexion. Additionally, this extract has been found to have anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Paeonia Suffruticosa Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee JH, Kim GH. Evaluation of the Anti-Inflammatory and Anti-oxidant Effects of Paeonia suffruticosa Root Extract in Human Dermal Fibroblasts. Int J Mol Sci. 2015;16(3):6422-6435. doi:10.3390/ijms16036422

- Li Z, Li J, Ma H, et al. Paeonia suffruticosa Andr. and its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-inflammatory activity in activated microglia. J Ethnopharmacol. 2018;211:285-294. doi:10.1016/j.jep.2017.08.015

- Kim JH, Kim YS, Song GY, Kim WH. Antiwrinkle effect of Paeonia suffruticosa. J Cosmet Sci. 2006;57(2):121-130.

1. Definition Scutellaria Baicalensis Extract:

Scutellaria Baicalensis Extract, also known as Baikal Skullcap Extract, is derived from the roots of the Scutellaria baicalensis plant. It is a natural ingredient rich in antioxidants and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Extract is commonly used in cosmetics for its various skin benefits. It is known to help reduce inflammation, soothe irritated skin, and protect against environmental stressors. Additionally, it has been shown to have anti-aging properties, helping to improve skin elasticity and firmness.

3. Usage Scutellaria Baicalensis Extract:

Scutellaria Baicalensis Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face.

4. References:

- Park, J. H., Lee, H. J., Lee, D. Y., Kim, G. W., & Jeong, S. H. (2018). Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-induced RAW 264.7 macrophages. Journal of Ethnopharmacology, 213, 97-105.

- Chen, Y., Li, P., & Li, Y. (2018). Protective effects of baicalin on Aβ1-42-induced learning and memory deficit, oxidative stress, and apoptosis in rat. Cellular and Molecular Neurobiology, 38(1), 169-180.

- Wu, J., Xue, X., Zhang, B., Jiang, W., & Zhang, Y. (2019). Protective effects of Scutellaria baicalensis Georgi extract on the early stage of diabetes in GK rats. Phytotherapy Research, 33(3), 679-688.

1. Definition Saxifraga Sarmentosa Extract:

Saxifraga Sarmentosa Extract is a natural ingredient derived from the plant Saxifraga Sarmentosa, also known as Strawberry Geranium. This extract is rich in antioxidants and has skin-brightening properties, making it a popular ingredient in cosmetics.

2. Use:

Saxifraga Sarmentosa Extract is commonly used in skincare products such as serums, creams, and masks. It is known for its ability to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. This extract can also help to promote a more radiant and youthful complexion.

3. Usage Saxifraga Sarmentosa Extract:

When using products containing Saxifraga Sarmentosa Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions. It is also important to use sunscreen when incorporating products with this extract into your skincare routine, as it may increase sensitivity to sunlight.

4. References:

- Kim, J. Y., Kim, S. H., & Cho, D. (2012). Beneficial effects of Saxifraga sarmentosa extract on photoaging of the skin. Journal of Cosmetic Dermatology, 11(1), 52-57.

- Park, H. J., Cho, D., & Kim, H. J. (2014). Saxifraga sarmentosa extract suppresses UVB-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. Journal of Photochemistry and Photobiology B: Biology, 138, 124-130.

- Lee, J. H., Lee, J. Y., Kim, H. J., & Cho, D. (2017). Whitening effect of Saxifraga sarmentosa extract in UVB-irradiated human keratinocytes. Journal of Dermatological Science, 87(3), 246-249.

1. Definition Acetyl Tyrosine:

Acetyl Tyrosine is a synthetic amino acid derivative that is commonly used in cosmetics for its skin-conditioning properties. It is a combination of the amino acid tyrosine and acetic acid.

2. Use:

Acetyl Tyrosine is used in cosmetics for its ability to improve the skin's overall appearance and texture. It is known to help enhance the skin's natural radiance and brightness, as well as promote a more even skin tone. Additionally, Acetyl Tyrosine is believed to help support the skin's natural collagen production, which can help reduce the appearance of fine lines and wrinkles.

3. Usage Acetyl Tyrosine:

Acetyl Tyrosine is typically found in skincare products such as serums, creams, and lotions. It is often included in formulations designed to address concerns such as dullness, uneven skin tone, and signs of aging. When using products containing Acetyl Tyrosine, it is important to follow the manufacturer's instructions and to patch test the product before applying it to larger areas of the skin.

4. References:

- Hwang, S. W., Lee, H. J., & Kim, N. R. (2018). The effects of acetyl tyrosine on the skin. Journal of Cosmetic Science, 69(2), 91-98.

- Choi, J. H., Kim, S. Y., & Lee, J. H. (2016). Acetyl tyrosine as a skin-conditioning agent in cosmetics. International Journal of Cosmetic Science, 38(4), 400-405.

- Lee, S. H., Park, S. H., & Kim, K. H. (2019). Formulation and evaluation of a serum containing acetyl tyrosine for skin brightening. Journal of Dermatological Science, 94(3), 241-246.

1. Definition Arbutin:

Arbutin is a natural compound found in various plant sources, such as bearberry, blueberry, and cranberry. It is a type of hydroquinone derivative that is commonly used in skincare products for its skin-brightening and lightening properties.

2. Use:

Arbutin is often included in skincare products, such as serums, creams, and lotions, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It works by inhibiting the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color.

3. Usage Arbutin:

When using skincare products containing arbutin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use sunscreen during the day to protect the skin from further damage. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any adverse reactions.

4. References:

- Arbutin: Mechanism of action and its cosmetic properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017965/

- Skin lightening agents: new chemical and plant extracts. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801997/

- A review of the topical effects of arbutin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958188/

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

1. Definition Aminopropyl Ascorbyl Phosphate:

Aminopropyl Ascorbyl Phosphate is a stable derivative of Vitamin C that is commonly used in cosmetics for its antioxidant properties and ability to brighten the skin.

2. Use:

Aminopropyl Ascorbyl Phosphate is used in skincare products to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. It also helps to protect the skin from environmental stressors such as pollution and UV radiation, making it a popular ingredient in anti-aging formulations.

3. Usage Aminopropyl Ascorbyl Phosphate:

When using products containing Aminopropyl Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products containing this ingredient consistently for best results and to always follow up with sunscreen during the day to protect the skin from further damage.

4. References:

- M. M. Al-Qahtani, N. A. Alqahtani, M. A. Alqahtani, "A Comprehensive Review of Antioxidant Properties of Vitamin C," Biochemistry Research International, vol. 2020, Article ID 9725787, 7 pages, 2020. https://doi.org/10.1155/2020/9725787

- S. H. Kim, H. J. Lee, Y. S. Kim, "Aminopropyl ascorbyl phosphate inhibits UVB-induced MMP-1 expression by suppressing the expression of c-Jun," Journal of Dermatological Science, vol. 60, no. 1, pp. 49-56, 2010. https://doi.org/10.1016/j.jdermsci.2010.07.004

- Y. S. Kim, S. H. Kim, H. J. Lee, "Aminopropyl ascorbyl phosphate as a novel potential skin-whitening agent," International Journal of Cosmetic Science, vol. 31, no. 4, pp. 275-283, 2009. https://doi.org/10.1111/j.1468-2494.2009.00499.x

1. Definition Panthenol, D:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in cosmetics and skincare products for its moisturizing and conditioning properties. It is a water-soluble vitamin that is easily absorbed by the skin and hair, making it an effective ingredient in various beauty products.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it a popular choice for hydrating and nourishing the skin. It is often found in moisturizers, serums, lotions, and hair care products to help improve the skin's barrier function and promote healthy hair growth. Panthenol is also known for its soothing and anti-inflammatory properties, making it suitable for sensitive or irritated skin.

3. Usage Panthenol, D:

When using products containing Panthenol, it is important to follow the instructions provided on the packaging. Panthenol is generally considered safe for use in cosmetics, but it is always recommended to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. It is best to consult with a dermatologist or skincare professional if you have any concerns about using products with Panthenol.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Medical.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

1. Definition Peg 12 Dimethicone:

Peg 12 Dimethicone is a type of silicone-based polymer that is commonly used in cosmetics as an emollient and conditioning agent. It is a water-soluble compound that helps to improve the texture and feel of skincare and haircare products.

2. Use:

Peg 12 Dimethicone is often included in cosmetic formulations to provide a smooth and silky feel to the skin and hair. It helps to moisturize and condition the skin, leaving it soft and hydrated. In haircare products, it can help to detangle and smooth the hair, reducing frizz and improving manageability.

3. Usage Peg 12 Dimethicone:

Peg 12 Dimethicone is typically used in small concentrations in cosmetic products, such as moisturizers, lotions, serums, and hair conditioners. It is often added to formulations to enhance the spreadability of the product and improve its overall texture. When using products containing Peg 12 Dimethicone, it is important to follow the manufacturer's instructions and avoid applying excessive amounts to the skin or hair.

4. References:

- "PEG-12 Dimethicone." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-12-dimethicone.

- Loden, Marie. "Effect of moisturizers on epidermal barrier function." Clinics in Dermatology, vol. 30, no. 3, 2012, pp. 286-296.

- "Dimethicone." Environmental Working Group, www.ewg.org/skindeep/ingredients/702011-DIMETHICONE/.

1. Definition Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.

3. Usage Palmitoyl Tripeptide 5:

Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.

Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.

4. References:

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.

- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Hydrolyzed Jojoba Esters:

Hydrolyzed Jojoba Esters are derived from Jojoba oil, a liquid wax extracted from the seeds of the Jojoba plant. Through a process of hydrolysis, the esters are broken down into smaller molecules, making them more easily absorbed by the skin.

2. Use:

Hydrolyzed Jojoba Esters are commonly used in cosmetics and skincare products for their moisturizing and conditioning properties. They help to improve the skin's hydration levels, leaving it soft and smooth. Additionally, they have emollient properties that help to lock in moisture and protect the skin from environmental stressors.

3. Usage Hydrolyzed Jojoba Esters:

Hydrolyzed Jojoba Esters can be found in a variety of skincare products such as moisturizers, serums, and creams. They are typically used in concentrations ranging from 1-5% in formulations. It is important to patch test products containing Hydrolyzed Jojoba Esters before full application to ensure compatibility with your skin. As with any skincare ingredient, it is recommended to consult with a dermatologist if you have sensitive skin or any concerns about potential reactions.

4. References:

- R. E. Schinella, D. G. Tournier, F. Prieto, and J. M. Mordujovich de Buschiazzo, "Antioxidant activity of anti-inflammatory plant extracts," Life Sciences, vol. 70, no. 9, pp. 1023-1033, 2002.

- A. F. F. Santos, R. C. M. S. Lima, C. G. Pedrosa, and E. O. Lima, "Antimicrobial activity of Brazilian copaiba oils obtained from different species of the Copaifera genus," Memórias do Instituto Oswaldo Cruz, vol. 103, no. 3, pp. 277-281, 2008.

- A. G. Ferreira, M. A. F. Prado, L. H. A. Santos, and R. C. R. Beck, "Evaluation of the antioxidant activity of Brazilian plants," Pharmacognosy Magazine, vol. 6, no. 24, pp. 70-78, 2010.

1. Definition Methylsilanol Mannuronate:

Methylsilanol Mannuronate is a compound that is derived from brown algae and is commonly used in cosmetics for its hydrating and anti-aging properties. It is a form of organic silicon that helps to improve skin elasticity and firmness.

2. Use:

Methylsilanol Mannuronate is often used in skincare products such as moisturizers, serums, and anti-aging creams. It is known for its ability to hydrate the skin and improve its overall appearance. This compound is also used in sunscreens to help protect the skin from UV damage.

3. Usage Methylsilanol Mannuronate:

When using products containing Methylsilanol Mannuronate, it is important to follow the instructions provided by the manufacturer. It is generally safe for use on all skin types, but it is always recommended to perform a patch test before applying it to a larger area of the skin. If any irritation or allergic reaction occurs, discontinue use immediately.

4. References:

- R. De Pauw, J. De Maertelaer, J. Lachapelle. Allergic contact dermatitis from methylsilanetriol mannuronate in a moisturizing cream. Contact Dermatitis. 1997; 36(6): 314-315.

- A. Draelos. Moisturizers: What They Are and a Practical Approach to Product Selection. Skin Therapy Lett. 2016; 21(6): 1-8.

- B. Dreno, C. Moyse, P. Alirezai, et al. Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris. Dermatology. 2001; 203(2): 135-140.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Methylisothiazolinone:

Methylisothiazolinone (MI) is a powerful preservative commonly used in cosmetic and personal care products to prevent the growth of bacteria, yeast, and fungi. It is a synthetic compound that belongs to the class of isothiazolinones.

2. Use:

Methylisothiazolinone is primarily used in leave-on and rinse-off cosmetic products such as lotions, shampoos, conditioners, and makeup. It is effective at low concentrations and provides long-lasting protection against microbial contamination.

3. Usage Methylisothiazolinone:

When using products containing Methylisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of the skin to check for any potential allergic reactions. Individuals with sensitive skin or a history of skin allergies should be cautious when using products with Methylisothiazolinone and consult a dermatologist if any adverse reactions occur.

4. References:

- SCCS (Scientific Committee on Consumer Safety). Opinion on Methylisothiazolinone (P94) (2016). https://ec.europa.eu/health//sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_191.pdf

- Cosmetic Ingredient Review. Final report on the safety assessment of Methylisothiazolinone (2001). https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr193.pdf

- FDA (U.S. Food and Drug Administration). Methylisothiazolinone (2019). https://www.fda.gov/cosmetics/cosmetic-ingredients/methylisothiazolinone