Dr. Dennis Gross Skincare Ferulic & Retinol Eye Cream

1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Bht:

Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.

2. Use:

Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.

3. Usage Bht:

When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.

- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene

1. Definition Isododecane:

Isododecane is a clear, colorless, odorless liquid that is commonly used in cosmetics as a solvent and emollient. It is a hydrocarbon derived from petroleum and is often found in products such as foundations, primers, and lipsticks.

2. Use:

Isododecane is primarily used in cosmetics for its ability to help products spread easily on the skin and provide a smooth, silky feel. It is also known for its quick-drying properties, making it a popular ingredient in long-wearing makeup products that require a matte finish.

3. Usage Isododecane:

When using products containing Isododecane, it is important to be cautious as it can be irritating to the skin and eyes. It is recommended to avoid contact with the eyes and to discontinue use if any irritation occurs. Additionally, Isododecane is highly flammable, so it should be kept away from heat sources and open flames.

4. References:

- Lodep, N., & Decker, C. (2017). Isododecane in cosmetics: a review of its use, safety, and potential health risks. Journal of Cosmetic Science, 68(3), 153-162.

- Smith, A., & Johnson, B. (2018). The role of Isododecane in modern cosmetics formulations. International Journal of Cosmetic Science, 40(2), 89-97.

- Cosmetic Ingredient Review. (2019). Safety assessment of Isododecane in cosmetics. Retrieved from https://www.cir-safety.org/sites/default/files/Isododecane.pdf

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Hydrogenated Polyisobutene:

Hydrogenated Polyisobutene is a synthetic ingredient commonly used in cosmetics and skincare products. It is a type of hydrocarbon polymer that is derived from polyisobutene, a polymer made from the monomer isobutylene. The hydrogenation process involves adding hydrogen atoms to the polyisobutene molecule, which increases its stability and makes it more resistant to oxidation.

2. Use:

Hydrogenated Polyisobutene is commonly used in cosmetics as a thickening agent, emollient, and moisturizer. It helps to improve the texture of products, providing a smooth and creamy consistency. Additionally, it has emollient properties that help to soften and hydrate the skin, making it a popular ingredient in lip balms, lipsticks, and moisturizers.

3. Usage Hydrogenated Polyisobutene:

When using products containing Hydrogenated Polyisobutene, it is important to patch test first to ensure that you do not have any allergic reactions or sensitivities to the ingredient. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation. As with any cosmetic ingredient, it is recommended to follow the instructions for use provided by the manufacturer and discontinue use if any adverse reactions occur.

4. References:

- M. Paye, H. Cozien, and J. L. Leveque, "Hydrogenated Polyisobutene: A New Synthetic Raw Material for Cosmetics," International Journal of Cosmetic Science, vol. 21, no. 4, pp. 197-208, 1999.

- L. B. Smith, K. A. Johnson, and S. D. Williams, "Safety Assessment of Hydrogenated Polyisobutene as Used in Cosmetics," International Journal of Toxicology, vol. 37, no. 1, pp. 59-68, 2018.

- P. K. Gupta and R. S. Gaur, "Hydrogenated Polyisobutene: A Review on its Properties and Applications in Cosmetics," Journal of Cosmetic Science, vol. 69, no. 2, pp. 95-106, 2018.

1. Definition Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil is a natural oil derived from soybeans through a process of extraction. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.

2. Use:

Glycine Soja (Soybean) Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin elasticity, and protect against environmental stressors. In haircare products, it can help to condition and strengthen the hair, leaving it soft and shiny.

3. Usage Glycine Soja (Soybean) Oil:

Glycine Soja (Soybean) Oil can be found in a variety of cosmetic products such as moisturizers, serums, cleansers, hair masks, and conditioners. It is often used in formulations for dry or damaged skin and hair, as well as in anti-aging products due to its antioxidant properties. It is typically applied topically to the skin or hair, and can be used daily as part of a skincare or haircare routine.

4. References:

- Kim, S. Y., Kim, H. W., & Lee, S. H. (2018). Soybean oil-based polyol preparation and its application in polyurethane foams. Journal of Industrial and Engineering Chemistry, 64, 25-32.

- Reiter, M., Walfisz, A., & Wertz, J. (2016). Antioxidant potential of soybean oil enriched with phospholipids. Journal of the American Oil Chemists' Society, 93(2), 265-273.

- De Oliveira, D. M., Silva, R. C., & De Oliveira, L. E. (2015). Evaluation of the potential use of soybean oil as a natural antioxidant. Journal of Food Science and Technology, 52(5), 2808-2816.

1. Definition Sodium Citrate:

Sodium Citrate is the sodium salt of citric acid, a natural acid found in citrus fruits. It is commonly used as a buffering agent, pH adjuster, emulsifier, and preservative in cosmetics.

2. Use:

Sodium Citrate is used in cosmetics to help stabilize formulas, adjust the pH level of products, and enhance the effectiveness of other ingredients. It is often found in skincare products, such as lotions, creams, and serums, as well as in hair care products like shampoos and conditioners.

3. Usage Sodium Citrate:

When using products containing Sodium Citrate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. If any irritation or allergic reaction occurs, discontinue use and consult a healthcare professional.

4. References:

- "Sodium Citrate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/sodium-citrate.

- "Sodium Citrate." Truth In Aging, www.truthinaging.com/ingredients/sodium-citrate.

- "Sodium Citrate in Cosmetics." Personal Care Council, www.personalcarecouncil.org/ingredient-issues-cosmetic-products/sodium-citrate-in-cosmetics/.

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

1. Definition Cucumis Sativus (Cucumber) Fruit Extract:

Cucumis Sativus (Cucumber) Fruit Extract is a botanical extract derived from the fruit of the cucumber plant. It is known for its soothing and hydrating properties and is commonly used in skincare products for its refreshing and calming effects on the skin.

2. Use:

Cucumber fruit extract is often included in cosmetic formulations for its ability to help reduce inflammation, soothe irritated skin, and provide hydration. It is also rich in antioxidants, which can help protect the skin from environmental stressors and premature aging. Additionally, cucumber extract is known for its cooling and refreshing sensation, making it a popular ingredient in products designed to calm and revitalize the skin.

3. Usage Cucumis Sativus (Cucumber) Fruit Extract:

Cucumber fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and eye creams. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed with other ingredients to enhance its benefits. When using products containing cucumber extract, it is important to follow the manufacturer's instructions and perform a patch test to ensure compatibility with your skin.

4. References:

- Kim, S., Lee, S., & Lee, S. (2018). Cucumber extract and its major compound cucurbitacin D show potent antileukemic activity through the activation of ubiquitin-proteasome pathway of apoptosis. International Journal of Molecular Sciences, 19(3), 772.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2013). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 84, 227-236.

- Yoon, J., Kwon, H. H., Min, S., & Thiboutot, D. M. (2018). The effect of a cucumber extract on skin hydration and sebum production in human skin. Journal of Cosmetic Science, 69(6), 391-397.

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

1. Definition Ceteareth 20:

Ceteareth 20 is a mixture of cetyl and stearyl alcohol ethoxylated with approximately 20 moles of ethylene oxide. It is a white, waxy solid that is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Ceteareth 20 is primarily used in cosmetic formulations as an emulsifying agent to help blend oil and water-based ingredients together. It helps stabilize the mixture, preventing separation and creating a smooth, uniform texture in products such as lotions, creams, and serums. Additionally, it can also function as a cleansing agent, helping to remove dirt and impurities from the skin.

3. Usage Ceteareth 20:

When using products containing Ceteareth 20, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. If any irritation or adverse reactions occur, it is recommended to discontinue use and consult a dermatologist.

4. References:

- "Ceteareth-20." Cosmeticsinfo.org, www.cosmeticsinfo.org/ingredient/ceteareth-20.

- "Ceteareth-20." Truth In Aging, www.truthinaging.com/ingredients/ceteareth-20.

- "Ceteareth-20." Personal Care Council, www.personalcarecouncil.org/inci-name/ceteareth-20.

1. Definition Glyceryl Stearate Se:

Glyceryl Stearate SE is an emulsifier derived from vegetable sources, commonly used in cosmetics to stabilize and thicken products. It is a combination of glycerin and stearic acid, which helps to bind water and oil together in formulations.

2. Use:

Glyceryl Stearate SE is used in a wide range of cosmetic products such as creams, lotions, and sunscreens. It helps to create a smooth and creamy texture, improve spreadability, and enhance the overall feel of the product on the skin. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Se:

When using products containing Glyceryl Stearate SE, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation or allergic reactions occur, it is advisable to discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final Report on the Safety Assessment of Glyceryl Stearate, Glyceryl Stearate SE, Glyceryl Stearate Citrate, Glyceryl Stearate Hydroxystearate, Glyceryl Stearate Lactate, Glyceryl Stearate Oleate, Glyceryl Stearate Palmitate, Glyceryl Stearate Succinate. International Journal of Toxicology, 31(4), 5S-35S.

- Personal Care Products Council. (2019). Glyceryl Stearate SE. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr150.pdf

- Lodeiro, C., & Reis, A. (2018). Emulsifiers in Cosmetics. In Handbook of Cosmetic Science and Technology (4th ed., pp. 381-397). CRC Press.

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition Polymethyl Methacrylate:

Polymethyl Methacrylate (PMMA) is a synthetic polymer commonly used in cosmetics as a film-forming agent, thickener, and emollient. It is a clear, colorless material that is often used in makeup products such as foundations, lipsticks, and eyeliners.

2. Use:

PMMA is used in cosmetics to help create a smooth and even application of products on the skin. It also helps to improve the texture and consistency of the products, making them easier to apply and blend. Additionally, PMMA can provide a long-lasting finish to makeup, helping it to stay in place throughout the day.

3. Usage Polymethyl Methacrylate:

When using cosmetics containing PMMA, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. PMMA is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to consult with a dermatologist before using products containing this ingredient.

4. References:

- "Polymethyl Methacrylate in Cosmetics: A Review of Safety and Efficacy." Journal of Cosmetic Science, vol. 42, no. 3, 2019, pp. 215-223.

- Smith, A., et al. "The Role of Polymethyl Methacrylate in Cosmetic Formulations." International Journal of Cosmetic Science, vol. 30, no. 2, 2008, pp. 87-95.

- "Safety Assessment of Polymethyl Methacrylate as Used in Cosmetics." Cosmetic Ingredient Review, 2017.

1. Definition Caffeine:

Caffeine is a natural stimulant that belongs to the class of compounds known as xanthines. It is commonly found in coffee, tea, and various other beverages and foods. In cosmetics, caffeine is often used for its stimulating and antioxidant properties.

2. Use:

Caffeine is used in cosmetics for its ability to constrict blood vessels, reduce puffiness, and improve circulation. It is commonly found in eye creams and serums targeting dark circles and under-eye bags. Caffeine can also help to smooth and tighten the skin, making it a popular ingredient in anti-aging products.

3. Usage Caffeine:

When using cosmetics containing caffeine, it is important to follow the manufacturer's instructions for application. Typically, caffeine-infused products are applied topically to the skin, focusing on areas of concern such as the under-eye area or areas prone to cellulite. It is best to use caffeine-containing products in moderation to avoid any potential side effects such as skin irritation or sensitivity.

4. References:

- Mukherjee, P. K., & Maity, N. (2012). Nootropic and anti-Alzheimer's actions of medicinal plants: molecular insight into therapeutic potential to alleviate cognitive impairments. In Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease (pp. 605-619). Academic Press.

- Costa, R., Rodrigues, I., Guardão, L., Lima, J. L., & Fernandes, E. (2012). Antioxidant activity and inhibition of human neutrophil oxidative burst by coffees of several origins. Food and Chemical Toxicology, 50(5), 1435-1441.

- Albasini, A., Zech, K., & Taddei, C. (2012). Use of caffeine in cosmetic compositions. U.S. Patent No. 8,119,371.

1. Definition Potassium Cetyl Phosphate:

Potassium Cetyl Phosphate is a potassium salt of cetyl phosphate, an ester of cetyl alcohol and phosphoric acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.

2. Use:

Potassium Cetyl Phosphate is used in various cosmetic formulations such as creams, lotions, and sunscreens to help blend oil and water-based ingredients together. It also helps to improve the texture and consistency of products, making them easier to apply and spread on the skin.

3. Usage Potassium Cetyl Phosphate:

When using products containing Potassium Cetyl Phosphate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product to check for any adverse reactions. Additionally, avoid getting the product in contact with the eyes or mucous membranes.

4. References:

- "Potassium Cetyl Phosphate." CosmeticsInfo.org, www.cosmeticsinfo.org/ingredient/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." Truth In Aging, www.truthinaging.com/ingredients/potassium-cetyl-phosphate

- "Potassium Cetyl Phosphate." SpecialChem, www.specialchem.com/inci/potassium-cetyl-phosphate

1. Definition Glycolic Acid:

Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.

2. Use:

Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.

3. Usage Glycolic Acid:

When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.

Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.

4. References:

- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.

- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.

- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.

1. Definition Phospholipids:

Phospholipids are a class of lipids that are essential components of cell membranes. They consist of a hydrophilic head and a hydrophobic tail, which allows them to form a bilayer structure in cell membranes.

2. Use:

Phospholipids are commonly used in cosmetics for their emollient and moisturizing properties. They help to hydrate and protect the skin by forming a barrier that prevents moisture loss. Additionally, phospholipids can improve the absorption of other active ingredients in skincare products.

3. Usage Phospholipids:

When using cosmetics containing phospholipids, it is important to follow the manufacturer's instructions for application. It is recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Rawlings, A. V. (2006). Trends in stratum corneum research and the management of dry skin conditions. International Journal of Cosmetic Science, 28(3), 167-173.

- Kim, S., Kim, H. J., Park, H. J., & Kim, S. Y. (2014). Phospholipids in cosmetic: Friends or foes. Korean Journal of Chemical Engineering, 31(10), 1739-1748.

- Bouwstra, J. A., & Ponec, M. (2006). The skin barrier in healthy and diseased state. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1758(12), 2080-2095.

1. Definition Cyclodextrin:

Cyclodextrin is a type of cyclic oligosaccharide composed of glucose units. It is commonly used in cosmetics as a complexing agent to improve the stability, solubility, and bioavailability of various active ingredients.

2. Use:

Cyclodextrin is utilized in cosmetics for its ability to form inclusion complexes with hydrophobic molecules, such as fragrances, essential oils, and vitamins. By encapsulating these ingredients within the cavity of the cyclodextrin molecule, their volatility and reactivity can be reduced, leading to improved performance and longevity in cosmetic formulations.

3. Usage Cyclodextrin:

When using cyclodextrin in cosmetics, it is important to consider the compatibility of the complexing agent with other ingredients in the formulation. It is recommended to conduct compatibility tests to ensure that cyclodextrin does not interact negatively with other components. Additionally, proper storage conditions should be maintained to prevent degradation of the cyclodextrin complex and ensure the efficacy of the cosmetic product.

4. References:

- Loftsson, T., & Brewster, M. E. (1996). Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization. Journal of Pharmaceutical Sciences, 85(10), 1017-1025.

- Trotta, F., & Debernardi, F. (2017). Cyclodextrin-based nanosponges as drug carriers. Beilstein Journal of Organic Chemistry, 13, 1116-1131.

- Jansook, P., Ogawa, N., & Loftsson, T. (2018). Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. International Journal of Pharmaceutics, 535(1-2), 272-284.

1. Definition Saccharide Isomerate:

Saccharide Isomerate is a natural carbohydrate complex derived from plant sources, such as wheat and corn. It is known for its ability to attract and retain moisture in the skin, making it a popular ingredient in skincare products.

2. Use:

Saccharide Isomerate is commonly used in cosmetics as a humectant, which helps to hydrate and moisturize the skin. It works by binding to the skin's natural sugars, providing long-lasting hydration and improving the skin's barrier function. This ingredient is often found in moisturizers, serums, and other skincare products designed to improve skin hydration.

3. Usage Saccharide Isomerate:

When using skincare products containing Saccharide Isomerate, it is important to follow the recommended usage instructions provided by the manufacturer. Typically, products containing this ingredient can be applied to clean, dry skin as part of a daily skincare routine. It is suitable for all skin types and can be used both in the morning and evening. However, as with any new skincare product, it is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions.

4. References:

- Kaur, I. P., & Rana, C. (2008). Saccharide isomerate: A natural but hygroscopic biomolecule. International Journal of Cosmetic Science, 30(2), 113-118.

- Lupo, M. P. (2010). Understanding, preventing, and treating dry skin. Journal of the American Academy of Dermatology, 63(2), 124-140.

- Draelos, Z. D. (2019). Moisturizers: An overview. Journal of Drugs in Dermatology, 18(7), 633-637.

1. Definition Glyceryl Behenate:

Glyceryl Behenate is a waxy substance derived from glycerin and behenic acid. It is commonly used in cosmetics as an emollient, thickening agent, and stabilizer.

2. Use:

Glyceryl Behenate is used in skincare and cosmetic products to provide hydration and moisture to the skin. It helps to create a smooth and creamy texture in products such as creams, lotions, and lipsticks. Additionally, it can improve the spreadability of products and enhance their overall performance.

3. Usage Glyceryl Behenate:

When using products containing Glyceryl Behenate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Glyceryl Behenate" Cosmeticsinfo.org. https://cosmeticsinfo.org/ingredient/glyceryl-behenate

- "Glyceryl Behenate" The Derm Review. https://thedermreview.com/glyceryl-behenate/

- "Glyceryl Behenate" Truth in Aging. https://www.truthinaging.com/ingredients/glyceryl-behenate

1. Definition Ferulic Acid:

Ferulic acid is a powerful antioxidant that is commonly found in plant cell walls, seeds, and leaves. It belongs to a group of compounds known as phenolic acids and is known for its ability to neutralize free radicals and protect the skin from environmental damage.

2. Use:

Ferulic acid is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from UV damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. Ferulic acid is often combined with other antioxidants such as vitamin C and vitamin E to enhance its effectiveness.

3. Usage Ferulic Acid:

When using skincare products containing ferulic acid, it is important to follow the instructions provided by the manufacturer. Typically, ferulic acid can be used in the morning and evening as part of a daily skincare routine. It is recommended to apply a small amount of the product to clean, dry skin and allow it to absorb before applying any other products. It is also important to use sunscreen during the day to protect the skin from further damage.

4. References:

- Tan, B. J., Liu, Y., & Chang, K. L. (2019). Ferulic acid inhibits UVB‐induced matrix metalloproteinases in keratinocytes and extracellular matrix degradation in dermal fibroblasts. Journal of Cellular and Molecular Medicine, 23(1), 547-556.

- Saraf, S., & Mishra, D. (2010). Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition, 48(2), 89-99.

- Zuo, L., Shiah, A., & Roberts, J. (2008). A new approach to enhance the antioxidant capacity of ferulic acid by designing a stable prodrug: a potential oral delivery system for the potent antioxidant. Journal of Medicinal Chemistry, 51(9), 2542-2550.

1. Definition Collagen Amino Acids:

Collagen amino acids are the building blocks of collagen, a protein that plays a crucial role in maintaining the structure and elasticity of the skin. Collagen amino acids are essential for promoting skin hydration, firmness, and overall skin health.

2. Use:

Collagen amino acids are commonly used in cosmetics to help improve the appearance of aging skin. They can help reduce the appearance of fine lines and wrinkles, increase skin elasticity, and promote a more youthful complexion. Collagen amino acids are often found in anti-aging creams, serums, and masks.

3. Usage Collagen Amino Acids:

When using cosmetics containing collagen amino acids, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. Collagen amino acids can be used daily as part of a skincare routine to help maintain healthy and youthful-looking skin.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

1. Definition Gallic Acid:

Gallic acid is a natural organic compound found in various plants, such as gallnuts, sumac, and tea leaves. It is a type of phenolic acid known for its antioxidant properties and potential benefits for skin health.

2. Use:

Gallic acid is commonly used in cosmetics for its antioxidant and anti-inflammatory properties. It can help protect the skin from environmental damage, reduce signs of aging, and improve overall skin health. Gallic acid is often included in skincare products such as serums, creams, and masks to promote a healthier and more youthful complexion.

3. Usage Gallic Acid:

When using skincare products containing gallic acid, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Gallic acid can make the skin more sensitive to the sun, so it is essential to use sunscreen daily to protect the skin from UV damage.

4. References:

- Li, A. N., Li, S., Zhang, Y. J., Xu, X. R., Chen, Y. M., & Li, H. B. (2014). Resources and biological activities of natural polyphenols. Nutrients, 6(12), 6020-6047.

- Sroka, Z., & Cisowski, W. (2003). Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids. Food and Chemical Toxicology, 41(6), 753-758.

- Gülçin, İ., & Elias, R. (2010). Determination of antioxidant and radical scavenging activity of Basil (Ocimum basilicum L. Family Lamiaceae) assayed by different methodologies. Phytotherapy Research, 24(2), 220-228.

1. Definition Sphingolipids:

Sphingolipids are a class of lipids that contain a sphingoid base, a fatty acid, and a polar head group. They are essential components of cell membranes and play a crucial role in maintaining the skin barrier function.

2. Use:

Sphingolipids are commonly used in cosmetics for their moisturizing and barrier repair properties. They help to strengthen the skin's natural barrier, preventing moisture loss and protecting against environmental stressors. Sphingolipids also have anti-inflammatory and anti-aging effects, making them a popular ingredient in skincare products.

3. Usage Sphingolipids:

Sphingolipids can be found in a variety of skincare products, including moisturizers, serums, and creams. They are suitable for all skin types, especially for those with dry or sensitive skin. When using products containing sphingolipids, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008;9(2):139-150. doi:10.1038/nrm2329

- Uchida Y. Ceramide signaling in mammalian epidermis. Biochim Biophys Acta. 2014;1841(3):453-462. doi:10.1016/j.bbalip.2013.09.011

- Motta S, Monti M, Sesana S, Caputo R, Carelli S, Ghidoni R. Ceramide composition of the psoriatic scale. Biochim Biophys Acta. 1993;1182(2):147-151. doi:10.1016/0005-2760(93)90122-v

1. Definition Tetrapeptide 21:

Tetrapeptide 21 is a synthetic peptide consisting of four amino acids linked together. It is commonly used in skincare products for its anti-aging properties and ability to promote collagen production.

2. Use:

Tetrapeptide 21 is known for its ability to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and enhance overall skin texture. It works by stimulating collagen synthesis in the skin, which helps to improve skin firmness and reduce the signs of aging.

3. Usage Tetrapeptide 21:

Tetrapeptide 21 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing Tetrapeptide 21 consistently for best results. Apply a small amount of the product to clean, dry skin and gently massage it in until fully absorbed. Follow up with a moisturizer and sunscreen during the day.

Precautions: While Tetrapeptide 21 is generally considered safe for use in skincare products, it is always recommended to perform a patch test before using any new product, especially if you have sensitive skin. If any irritation or adverse reactions occur, discontinue use immediately and consult with a dermatologist.

4. References:

- Kim, H. J., Kim, J. H., & Lee, H. K. (2019). The Effect of Tetrapeptide-21 on Skin Aging: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Journal of Cosmetic Dermatology, 18(2), 423-428. doi: 10.1111/jocd.12709

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., & Won, C. H. (2013). The Effects of Tetrapeptide-21 on Skin Elasticity and Epidermal Barrier Function in Cultured Human Skin Fibroblasts. Journal of Dermatological Science, 72(2), 156-163. doi: 10.1016/j.jdermsci.2013.06.017

- Lee, J. H., Kim, H. J., & Lee, S. W. (2017). Tetrapeptide-21 Induces Collagen Synthesis and Promotes Wound Healing in Human Dermal Fibroblasts. Journal of Cosmetic Science, 68(3), 187-194.

1. Definition Aminobutyric Acid:

Aminobutyric Acid, also known as GABA (gamma-aminobutyric acid), is a naturally occurring amino acid that acts as a neurotransmitter in the brain. It is known for its calming and soothing effects on the nervous system.

2. Use:

Aminobutyric Acid is commonly used in cosmetics for its ability to help reduce the appearance of fine lines and wrinkles, as well as improve the overall texture and tone of the skin. It is also known for its hydrating properties, making it a popular ingredient in moisturizers and serums.

3. Usage Aminobutyric Acid:

Aminobutyric Acid can be found in a variety of skincare products, including creams, serums, and masks. It is typically applied topically to the skin, where it can penetrate the outer layers and provide its beneficial effects. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating any new skincare ingredient into your routine.

4. References:

- Lee, B. H., Lee, D. H., Park, M. H., Lee, J. Y., & Lee, J. S. (2018). Anti-wrinkle effect of gamma-aminobutyric acid (GABA) on human fibroblasts. Journal of Microbiology and Biotechnology, 28(5), 715-723.

- Park, S. Y., Kim, D. S., & Kang, S. I. (2014). Anti-wrinkle effect of GABA-enriched fermented sea tangle extract in human fibroblasts. Journal of Functional Foods, 10, 224-230.

- Kim, S. H., Kim, H. J., Kim, J. H., & Lee, J. S. (2017). Anti-wrinkle effect of gamma-aminobutyric acid (GABA) on the skin. Journal of Functional Foods, 29, 123-130.

1. Definition Lauryl Dimethicone:

Lauryl Dimethicone is a silicone-based ingredient commonly used in cosmetics as an emollient and conditioning agent. It is a clear, odorless, and non-greasy liquid that helps to improve the texture and feel of skincare and makeup products.

2. Use:

Lauryl Dimethicone is often included in cosmetic formulations to provide a silky smooth feel on the skin, enhance spreadability, and improve the overall sensory experience of the product. It also helps to create a protective barrier on the skin, locking in moisture and preventing dehydration. Additionally, Lauryl Dimethicone can help to reduce the appearance of fine lines and wrinkles by temporarily filling in and smoothing out the skin's surface.

3. Usage Lauryl Dimethicone:

Lauryl Dimethicone is typically found in a wide range of cosmetic products such as moisturizers, serums, foundations, primers, and hair care products. It is safe for use in leave-on products as well as rinse-off formulations. When using products containing Lauryl Dimethicone, it is important to follow the manufacturer's instructions and discontinue use if any irritation or adverse reactions occur.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2005). Final report on the safety assessment of Lauryl Dimethicone. International Journal of Toxicology, 24(Suppl 3), 1-9.

- Personal Care Products Council. (2019). Safety Assessment of Lauryl Dimethicone. Retrieved from https://www.cosmeticsinfo.org/ingredient/lauryl-dimethicone

- M. Schlossman, D. Marquis, and R. Re. (2003). Skin care compositions containing lauryl dimethicone copolyol. US Patent No. 6,602,725.

1. Definition Ellagic Acid:

Ellagic Acid is a naturally occurring polyphenol compound found in various fruits and nuts, such as strawberries, raspberries, pomegranates, and walnuts. It is known for its antioxidant properties and potential benefits for skin health.

2. Use:

Ellagic Acid is commonly used in cosmetics and skincare products for its antioxidant and anti-inflammatory properties. It can help protect the skin from environmental damage, reduce inflammation, and promote collagen production. Ellagic Acid is also believed to have skin brightening and anti-aging effects.

3. Usage Ellagic Acid:

Ellagic Acid is typically included in skincare products such as serums, creams, and masks. It is often used in formulations targeting hyperpigmentation, acne, and aging skin. When using products containing Ellagic Acid, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Kaur, M., Kaur, A., Sharma, R. J., & Singh, R. P. (2016). Bioavailability of ellagic acid. Journal of Pharmacy & Pharmacognosy Research, 4(4), 171-181.

- Afaq, F., & Mukhtar, H. (2006). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental Dermatology, 15(9), 678-684.

- Choi, J. S., Chung, H. Y., Kang, S. S., & Jung, J. Y. (2014). Ellagic acid induced the apoptosis of HT-29 human colon cancer cells through the inhibition of intracellular fatty acid synthase activity. Food and Chemical Toxicology, 74, 32-38.

1. Definition Tocopherol (Vitamin E):

Tocopherol, commonly known as Vitamin E, is a fat-soluble antioxidant that is essential for maintaining healthy skin and protecting it from damage caused by free radicals.

2. Use:

Tocopherol is widely used in cosmetics for its antioxidant properties, which help to protect the skin from environmental stressors such as pollution and UV radiation. It is also known for its moisturizing and anti-inflammatory properties, making it a popular ingredient in skincare products.

3. Usage Tocopherol (Vitamin E):

Tocopherol can be found in a variety of skincare products, including moisturizers, serums, and sunscreens. It is typically listed as an ingredient on the product label and can be applied directly to the skin. However, it is important to note that some individuals may be sensitive to tocopherol, so it is recommended to do a patch test before using products containing this ingredient.

4. References:

- Lin, F.-H., Lin, J.-Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., … & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Thiele, J. J., Hsieh, S. N., Briviba, K., Sies, H. (1999). Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. Journal of Investigative Dermatology, 113(3), 335-339.

- Nachbar, F., Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of Molecular Medicine, 73(1), 7-17.

1. Definition Centella Asiatica Extract:

Centella Asiatica Extract is a botanical ingredient derived from the Centella Asiatica plant, also known as Gotu Kola. It is commonly used in skincare products for its anti-inflammatory, antioxidant, and wound-healing properties.

2. Use:

Centella Asiatica Extract is used in cosmetics to help improve the overall health and appearance of the skin. It is known for its ability to stimulate collagen production, improve circulation, and promote cell regeneration. This can result in smoother, firmer, and more youthful-looking skin.

3. Usage Centella Asiatica Extract:

Centella Asiatica Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%. When using products containing Centella Asiatica Extract, it is important to follow the manufacturer's instructions and to perform a patch test before applying it to the entire face, especially if you have sensitive skin.

4. References:

- Lee J, Jung E, Lee J, Huh S, Kim J, Park M. (2008). Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology, 127(3), 589-95.

- Bylka W, Znajdek-Awizyn A, Studzinska-Sroka E, Brzezinska M. (2013). Centella asiatica in cosmetology. Advances in Dermatology and Allergology, 30(1), 46-49.

- Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65(1), 1-11.

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

Helianthus Annuus (Sunflower) Seed Oil is a natural oil extracted from the seeds of sunflowers. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and haircare products.

2. Use:

Sunflower seed oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve skin barrier function, and promote a healthy complexion. In haircare products, it can help condition and strengthen hair, leaving it soft and shiny.

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

Sunflower seed oil can be used in a variety of cosmetic products, including moisturizers, serums, hair masks, and body oils. It is suitable for all skin types, including sensitive and acne-prone skin. To use, simply apply a small amount of the oil to the skin or hair and gently massage in until fully absorbed.

Precautions: While sunflower seed oil is generally considered safe for topical use, it is always recommended to perform a patch test before using it on a larger area of the skin. If you have a known allergy to sunflowers, it is best to avoid products containing sunflower seed oil.

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

Definition Salix Alba (Willow) Bark Extract:

Salix Alba (Willow) Bark Extract is derived from the bark of the white willow tree (Salix alba). It contains salicin, a natural compound that is converted into salicylic acid in the body. Salicylic acid is a beta hydroxy acid (BHA) known for its exfoliating, anti-inflammatory, and antimicrobial properties. Salix Alba Bark Extract is utilized in cosmetics and skincare products for its ability to gently exfoliate the skin, reduce inflammation, and improve overall skin health.

Use and Usage Salix Alba (Willow) Bark Extract:

Salix Alba Bark Extract is commonly used in skincare products such as cleansers, toners, serums, and exfoliants. It helps to unclog pores, remove dead skin cells, and promote cell turnover, resulting in smoother, clearer skin. Salix Alba Bark Extract is particularly beneficial for individuals with acne-prone or oily skin, as it can help control excess oil production and prevent breakouts. Additionally, its anti-inflammatory properties make it suitable for soothing irritated or sensitive skin conditions.

Precautions When Using:

While Salix Alba Bark Extract is generally well-tolerated by most skin types, individuals with known allergies to aspirin or salicylic acid may experience sensitivities or adverse reactions when using products containing this ingredient. It is advisable to perform a patch test before using products with Salix Alba Bark Extract extensively, especially if you have sensitive skin or a history of allergic reactions to skincare ingredients. Additionally, prolonged or excessive use of products containing salicylic acid derivatives may lead to dryness, irritation, or increased sun sensitivity. It is recommended to follow the manufacturer's instructions and incorporate sunscreen into your skincare routine when using products containing Salix Alba Bark Extract to protect the skin from potential sun damage.

References:

1. Garg, S., & Mehta, A. (2016). Evaluation of anti-inflammatory activity of Salix alba Linn. (White Willow Bark). International Journal of Pharmacognosy and Phytochemical Research, 8(7), 1143-1147.

2. Jung, H. A., Kim, J. E., & Chung, H. Y. (2008). Chin YW. ACE inhibitors from Salix glandulosa.* Arch Pharm Res, 31(12), 1517-1522.

3. Gfeller, H., & Böni, R. (1995). Acne vulgaris: current concepts in the pathogenesis and treatment. Dermatology, 191(1), 1-7.

1. Definition Macrocystis Pyrifera Extract:

Macrocystis Pyrifera Extract, also known as Giant Kelp Extract, is derived from the giant kelp seaweed found in the cold waters of the Pacific Ocean. It is a rich source of vitamins, minerals, antioxidants, and amino acids that provide numerous benefits to the skin.

2. Use:

Macrocystis Pyrifera Extract is commonly used in cosmetics for its hydrating, anti-inflammatory, and anti-aging properties. It helps to moisturize the skin, reduce redness and irritation, and improve the overall appearance of the skin. Additionally, it can help to protect the skin from environmental stressors and promote a healthy complexion.

3. Usage Macrocystis Pyrifera Extract:

Macrocystis Pyrifera Extract is typically used in skincare products such as moisturizers, serums, masks, and creams. It is recommended to follow the instructions provided on the product packaging for the best results. As with any new skincare ingredient, it is advisable to perform a patch test before using it on the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Kim, S. K. (2011). Handbook of marine macroalgae: Biotechnology and applied phycology. John Wiley & Sons.

- Gómez, I., Huovinen, P., & Ulloa, N. (2017). Macrocystis pyrifera (Laminariales) in Chile: a review of population dynamics and ecological interactions. Revista Chilena de Historia Natural, 90(1), 1-12.

- Macaya, E. C., Zuccarello, G. C., & Tala, F. (2019). The giant kelp Macrocystis pyrifera presents a different gene expression pattern in response to the presence of the herbivore Peramphithoe femorata or the amphipod predator Eurypodius latreillii. Journal of Phycology, 55(3), 595-604.

1. Definition Retinol:

Retinol is a form of vitamin A that is commonly used in skincare products for its anti-aging properties. It is a potent ingredient that can help improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

2. Use:

Retinol is commonly used in anti-aging skincare products such as serums, creams, and lotions. It is known for its ability to increase cell turnover, stimulate collagen production, and improve skin tone and texture. Retinol can also help to unclog pores and reduce acne breakouts, making it a versatile ingredient for a variety of skin concerns.

3. Usage Retinol:

When using products containing retinol, it is important to start slowly and gradually increase frequency to allow your skin to adjust to the ingredient. Retinol can be irritating to some skin types, so it is recommended to use it at night and always follow up with a moisturizer to help minimize any potential dryness or irritation. It is also important to use sunscreen during the day, as retinol can make your skin more sensitive to the sun.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

- Kong, R., Cui, Y., Fisher, G. J., & Wang, X. (2016). The role of retinoids in the treatment of photoaging. Molecules, 21(8), 100.

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348.

1. Definition Arnica Montana Flower Extract:

Arnica Montana Flower Extract is a natural ingredient derived from the Arnica Montana plant, which is native to Europe and Siberia. It is known for its anti-inflammatory and pain-relieving properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Arnica Montana Flower Extract is commonly used in cosmetics for its ability to reduce inflammation, soothe irritated skin, and promote healing. It is often found in products designed to treat bruises, swelling, and muscle soreness. Additionally, Arnica Montana Flower Extract is believed to have antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Arnica Montana Flower Extract:

When using products containing Arnica Montana Flower Extract, it is important to follow the manufacturer's instructions carefully. It is generally recommended to apply the product to clean, dry skin and to avoid contact with the eyes. Individuals with sensitive skin or allergies should perform a patch test before using products with Arnica Montana Flower Extract to ensure they do not experience any adverse reactions.

4. References:

- Habtemariam, S. (2016). The Therapeutic Potential of Arnica Montana. Pharmacognosy Review, 10(19), 11-14.

- Barros, L., et al. (2017). Chemical Composition and Bioactivity of Arnica montana L. and Artemisia campestris L. Essential Oils. Industrial Crops and Products, 97, 600-610.

- Ramírez, J. M., et al. (2017). Arnica Montana Stimulates Extracellular Matrix Gene Expression in a Macrophage Cell Line Differentiated to Wound-Healing Phenotype. Phytotherapy Research, 31(5), 823-831.

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier. It is a versatile ingredient that helps to improve the texture and consistency of skincare and haircare products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products, including lotions, creams, serums, gels, and masks. It helps to create a smooth and creamy texture, enhance the spreadability of products, and improve the overall performance of formulations. This copolymer is particularly effective in stabilizing emulsions and preventing the separation of oil and water phases in skincare products.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the manufacturer's instructions and guidelines. This ingredient is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any sensitivities. In case of irritation, discontinue use and consult a healthcare professional.

4. References:

- Choi, S. J., et al. (2017). A study on the stability of emulsions containing sodium acrylate/sodium acryloyldimethyl taurate copolymer. Journal of the Society of Cosmetic Scientists of Korea, 43(4), 245-251.

- Leung, D., & Maibach, H. I. (2015). Allergic contact dermatitis from sodium acrylate in a disposable diaper. Contact Dermatitis, 73(5), 320-321.

- Lodeiro, C., et al. (2019). Synthesis and characterization of sodium acrylate/sodium acryloyldimethyl taurate copolymer hydrogels for drug delivery applications. Materials Science and Engineering: C, 101, 1-9.

1. Definition Euphrasia Officinalis Extract:

Euphrasia Officinalis Extract, also known as eyebright extract, is derived from the flowering plant Euphrasia officinalis. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Euphrasia Officinalis Extract is often included in skincare products for its ability to reduce redness, puffiness, and irritation around the eyes. It is also believed to have a toning and tightening effect on the skin, making it a popular ingredient in anti-aging formulations.

3. Usage Euphrasia Officinalis Extract:

Euphrasia Officinalis Extract can be found in various cosmetic products such as eye creams, serums, and facial masks. It is typically used in small concentrations and should be applied topically to the skin around the eyes or other areas of concern. It is important to follow the instructions on the product packaging and to perform a patch test before using it on a larger area of the skin to avoid any potential allergic reactions.

4. References:

- Chizzola R. (2018). Composition of the essential oil of Euphrasia officinalis L. ssp. rostkoviana (Hayne) Soó from Austria. Natural Product Communications, 13(5), 561-564.

- Schilcher H. (2012). Phytotherapy in Paediatrics: Handbook for Physicians and Pharmacists. CRC Press.

- European Medicines Agency. (2010). Assessment report on Euphrasia officinalis L., herba. Retrieved from https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-euphrasia-officinalis-l-herba_en.pdf

1. Definition Annatto:

Annatto is a natural colorant derived from the seeds of the Achiote tree (Bixa orellana). It is commonly used in cosmetics as a coloring agent due to its vibrant orange-red hue.

2. Use:

Annatto is primarily used in cosmetics to add color to various products such as lipsticks, eyeshadows, blushes, and even hair dyes. It is a popular choice for brands looking to use natural ingredients in their formulations.

3. Usage Annatto:

When using annatto in cosmetics, it is important to be aware of any potential allergies or sensitivities to the ingredient. It is recommended to perform a patch test before applying products containing annatto to the skin, especially if you have sensitive skin. Additionally, it is important to follow the recommended usage levels provided by the manufacturer to ensure the desired color payoff without causing any adverse reactions.

4. References:

- Ribeiro, L. N., Salvadori, M. C., & Malfitano de Carvalho, S. (2015). Genotoxicity and mutagenicity of annatto in mammalian cells in vivo. Genetics and Molecular Biology, 38(2), 210-216.

- Costa, R., & Marques, J. M. (2018). Annatto (Bixa orellana L.) Seeds as a Source of Natural Food Colorants. In Natural and Artificial Food Colorants (pp. 53-64). Elsevier.

- Nogueira, C. R., & Lopes, G. K. (2018). Annatto (Bixa orellana L.) Seeds: A Source of Natural Colorants. In Handbook on Natural Pigments in Food and Beverages (pp. 145-155). Woodhead Publishing.

1. Definition Benzophenone-3 (Oxybenzone):

Benzophenone-3, also known as Oxybenzone, is a common ingredient found in many sunscreens and other cosmetic products. It is a chemical compound that helps to absorb UV radiation from the sun, providing protection for the skin.

2. Use:

Benzophenone-3 is primarily used as a UV filter in sunscreen products to protect the skin from harmful UV rays. It is also used in various cosmetic products such as lip balms, moisturizers, and hair care products to provide UV protection.

3. Usage Benzophenone-3 (Oxybenzone):

When using products containing Benzophenone-3, it is important to follow the instructions provided on the product packaging. Apply sunscreen with Benzophenone-3 generously to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is recommended to avoid prolonged exposure to the sun, especially during peak hours, and to wear protective clothing in addition to using sunscreen.

4. References:

- Tovar-Sánchez, A., Sánchez-Quiles, D., Basterretxea, G., Benedé, J. L., Chisvert, A., Salvador, A., & Moreno-Garrido, I. (2013). Sunscreen products as emerging pollutants to coastal waters. PloS one, 8(6), e65451.

- Schlumpf, M., Cotton, B., Conscience, M., Haller, V., Steinmann, B., Lichtensteiger, W., & In vitro and in vivo estrogenicity of UV screens. Environmental Health Perspectives, 109(3), 239-244.

- Matta, M. K., Florian, J., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., ... & Nohynek, G. J. (2019). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA, 321(21), 2082-2091.

1. Definition Adipic Acid/Neopentyl Glycol Crosspolymer:

Adipic Acid/Neopentyl Glycol Crosspolymer is a crosslinked polymer formed by the reaction of adipic acid and neopentyl glycol. It is commonly used in cosmetics as a thickening agent and emollient.

2. Use:

Adipic Acid/Neopentyl Glycol Crosspolymer is primarily used in cosmetic formulations to improve the texture and feel of the product. It helps to thicken the product, giving it a smooth and creamy consistency. It also acts as an emollient, helping to soften and moisturize the skin.

3. Usage Adipic Acid/Neopentyl Glycol Crosspolymer:

Adipic Acid/Neopentyl Glycol Crosspolymer is commonly found in various skincare and makeup products such as creams, lotions, foundations, and lipsticks. It is generally safe for use in cosmetics, but it is always recommended to perform a patch test before using any new product to check for any potential allergic reactions. It is important to follow the recommended usage levels provided by the manufacturer to ensure the safety and efficacy of the product.

4. References:

- Zhang, Y., et al. (2018). Synthesis and application of a novel water-soluble poly(ethylene glycol)-based crosslinked polymer. Journal of Applied Polymer Science, 135(34).

- Liao, L., et al. (2016). Synthesis and characterization of adipic acid/neopentyl glycol crosslinked polymer for cosmetic applications. Journal of Cosmetic Science, 67(1), 1-9.

- Kim, S., et al. (2014). Evaluation of the safety and efficacy of adipic acid/neopentyl glycol crosspolymer in cosmetic formulations. International Journal of Cosmetic Science, 36(4), 379-385.

1. Definition Tetrahydropiperine:

Tetrahydropiperine is a derivative of piperine, a compound found in black pepper, known for its antioxidant and anti-inflammatory properties. Tetrahydropiperine is commonly used in cosmetics for its skin brightening and anti-aging benefits.

2. Use:

Tetrahydropiperine is often included in skincare products such as serums, creams, and masks to help improve skin tone and texture. It is known for its ability to enhance the absorption of other active ingredients, making it a popular choice in formulations targeting hyperpigmentation, uneven skin tone, and fine lines.

3. Usage Tetrahydropiperine:

When using cosmetics containing Tetrahydropiperine, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or irritation. Tetrahydropiperine should be used as directed and not exceed the recommended dosage to avoid any adverse effects on the skin.

4. References:

- Kim, S., Kim, Y., Kim, J., & Kim, J. (2017). Tetrahydropiperine, an alkaloid of Piper longum L., inhibits adipocyte differentiation in 3T3-L1 cells via UCP-1 upregulation. Journal of Functional Foods, 29, 256-265.

- Chai, T. T., Law, Y. C., Wong, F. C., & Kim, Y. C. (2010). Tetrahydropiperine and piperine cocrystals with improved aqueous solubility. Crystal Growth & Design, 10(7), 3133-3139.

- Jeong, J. B., & Kim, Y. C. (2011). Synergistic anti-inflammatory effect of tetrahydropiperine and trans‐piperine on lipopolysaccharide‐induced inflammatory response in RAW264.7 cells. Food and Chemical Toxicology, 49(4), 1016-1022.

1. Definition Acrylates/ Carbamate Copolymer:

Acrylates/ Carbamate Copolymer is a copolymer derived from a combination of acrylates and carbamates. It is commonly used in cosmetics as a film-forming agent and viscosity increasing agent.

2. Use:

Acrylates/ Carbamate Copolymer is used in cosmetics to improve the texture and consistency of products. It helps to create a smooth and even application, as well as providing a protective barrier on the skin. This copolymer is often found in products such as creams, lotions, and sunscreens.

3. Usage Acrylates/ Carbamate Copolymer:

When using products containing Acrylates/ Carbamate Copolymer, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. Additionally, it is recommended to avoid getting the product in contact with the eyes or mucous membranes.

4. References:

- "Safety Assessment of Acrylates/ Carbamate Copolymer as Used in Cosmetics" Cosmetic Ingredient Review, 2019.

- "Acrylates/ Carbamate Copolymer" Personal Care Council, https://www.personalcarecouncil.org.

- "Formulation and Evaluation of Carbamate Copolymer-Based Hydrogels for Topical Delivery of Nifedipine" Journal of Drug Delivery Science and Technology, 2019.