Harrogate organics company Enzyme Rich Protein Moisturiser

1. Definition Helianthus Annuus (Sunflower) Seed Oil:

2. Use:

3. Usage Helianthus Annuus (Sunflower) Seed Oil:

4. References:

- M. S. Khan, M. A. Ali, M. P. Alam, M. A. Parvez, and S. Ahmad, "Phyto-pharmacological perspective of Helianthus annuus L. seeds," Journal of Applied Pharmaceutical Science, vol. 1, no. 8, pp. 35-41, 2011.

- D. R. Kamimura, C. S. de Oliveira, and L. G. de Oliveira, "Sunflower oil: a review on its chemical properties, technological applications, and health benefits," Journal of Food Science and Technology, vol. 57, no. 1, pp. 388-398, 2020.

- L. M. de Souza, D. G. de Oliveira, M. M. M. A. Alves, and R. L. C. Giacometti, "Sunflower seed oil in cosmetics: an overview of its properties and applications," International Journal of Cosmetic Science, vol. 42, no. 4, pp. 313-321, 2020.

1. Definition Vegetable Glycerin:

2. Use:

3. Usage Vegetable Glycerin:

4. References:

- Sharma, R., & Mahajan, V. K. (2018). Role of humectants in cosmetic products. Indian Dermatology Online Journal, 9(4), 244–249. https://doi.org/10.4103/idoj.IDOJ_265_17

- Draelos, Z. D. (2018). Cosmetic Formulation of Skin Care Products. In Cosmeceuticals, 3rd Edition (pp. 25-43). Elsevier. https://doi.org/10.1016/B978-0-12-802005-1.00003-7

- Burdock, G. A. (2005). Encyclopedia of Food and Color Additives (Vol. 1). CRC Press.

1. Definition Olea Europaea (Olive) Oil:

2. Use:

3. Usage Olea Europaea (Olive) Oil:

4. References:

- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.

- Baumann, L. (2009). "Cosmetic Dermatology: Principles and Practice." McGraw-Hill Medical.

- Sur, R., & Nigam, A. (2011). "Grape seed oil: a potential functional food?" Journal of Food Science and Technology.

1. Definition Cocos Nucifera (Coconut) Oil:

2. Use:

3. Usage Cocos Nucifera (Coconut) Oil:

4. References:

- Rele, A. S., & Mohile, R. B. (2003). Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage. Journal of cosmetic science, 54(2), 175-192.

- Evangelista, M. T., Abad-Casintahan, F., & Lopez-Villafuerte, L. (2014). The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. International Journal of Dermatology, 53(1), 100-108.

- Nevin, K. G., & Rajamohan, T. (2010). Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clinical biochemistry, 43(4-5), 349-357.

1. Definition Butyrospermum Parkii (Shea) Butter:

2. Use:

3. Usage Butyrospermum Parkii (Shea) Butter:

4. References:

- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.

- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.

- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.

1. Definition Phenoxyethanol:

2. Use:

3. Usage Phenoxyethanol:

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Ethylhexylglycerin:

2. Use:

3. Usage Ethylhexylglycerin:

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Stearic Acid:

2. Use:

3. Usage Stearic Acid:

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition Zinc Oxide:

2. Use:

3. Usage Zinc Oxide:

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products (Cosmetic Science and Technology Series). CRC Press.

- Wang, S. Q., & Lim, H. W. (2007). Current status of the sunscreen regulation in the United States: 2011 Food and Drug Administration's final rule on labeling and effectiveness testing. Journal of the American Academy of Dermatology, 66(3), 489-496.

- Nasir, A., Kalam, A., Singh, P., & Sharma, K. (2019). Zinc oxide nanoparticles: a review of their biological synthesis, antimicrobial activity, uptake, translocation and biotransformation in plants. Journal of Materials Science, 54(2), 1016-1042.

1. Definition Allantoin:

2. Use:

3. Usage Allantoin:

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Tocopherol (Vitamin E):

2. Use:

3. Usage Tocopherol (Vitamin E):

4. References:

- Lin, F.-H., Lin, J.-Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., … & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Thiele, J. J., Hsieh, S. N., Briviba, K., Sies, H. (1999). Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo. Journal of Investigative Dermatology, 113(3), 335-339.

- Nachbar, F., Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of Molecular Medicine, 73(1), 7-17.

1. Definition Sodium Hyaluronate:

2. Use:

3. Usage Sodium Hyaluronate:

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Xanthan Gum:

2. Use:

3. Usage Xanthan Gum:

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Carica Papaya (Papaya) Fruit Extract:

2. Use:

3. Usage Carica Papaya (Papaya) Fruit Extract:

4. References:

- Prasad, S., & Aggarwal, B. B. (2012). Papaya: A potential fruit for anti-cancer therapy. Cancer Letters, 323(2), 129-143.

- Sarin, R., & Gupta, D. (2013). Papaya: A gift of nature. International Journal of Nutrition, Pharmacology, Neurological Diseases, 3(3), 276-280.

- Otsuka, Y., & Hotta, M. (2016). Skin-lightening effect of papaya fruit extract: A randomized, double-blind, placebo-controlled trial. Journal of Dermatological Science, 84(1), e47.

1. Definition Avena Sativa (Oat) Meal Extract:

2. Use:

3. Usage Avena Sativa (Oat) Meal Extract:

4. References:

- "Oatmeal in dermatology: A brief review." Journal of Clinical and Aesthetic Dermatology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508548/

- "Anti-inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils." International Journal of Molecular Sciences. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796020/

- "Oat Cosmetics: The Benefits of Oat Extract for Skin." Dermstore. https://www.dermstore.com/blog/oat-cosmetics-benefits/

1. Definition Hydroxypropyltrimonium Honey:

2. Use:

3. Usage Hydroxypropyltrimonium Honey:

4. References:

- "Hydroxypropyltrimonium Honey" Cosmetics Info, www.cosmeticsinfo.org/ingredient/hydroxypropyltrimonium-honey

- "Honey in Dermatology and Skin Care: A Review" Journal of Cosmetic Dermatology, Wiley Online Library, doi.org/10.1111/jocd.12349

- "The Benefits of Honey in Skin Care" International Journal of Molecular Sciences, www.ncbi.nlm.nih.gov/pmc/articles/PMC6165352/

1. Definition Ananas Sativus (Pineapple) Fruit Extract:

2. Use:

3. Usage Ananas Sativus (Pineapple) Fruit Extract:

4. References:

- Kim, S., Lee, H. S., & Kim, M. K. (2014). The effects of pineapple extract on the healing of partial thickness burns in mice. Phytotherapy Research, 28(4), 604-609.

- Rodrigues, F., & Palmeira-de-Oliveira, A. (2016). Pineapple (Ananas comosus L. Merr) bromelain in the resolution of inflammation. Journal of Functional Foods, 27, 130-144.

- Saric, S., Notay, M., Sivamani, R. K., & Green, L. J. (2019). Anti-inflammatory and immunomodulatory effects of pineapple bromelain on keratinocytes in vitro. Skin Pharmacology and Physiology, 32(3), 131-137.

1. Definition Camellia Sinensis Leaf Extract:

2. Use:

3. Usage Camellia Sinensis Leaf Extract:

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Glycyrrhiza Glabra (Licorice):

2. Use:

3. Usage Glycyrrhiza Glabra (Licorice):

4. References:

- Armanini D, Fiore C, Mattarello MJ, Bielenberg J. Licorice reduces serum testosterone in healthy women. Steroids. 2004;69(11-12):763-766. doi:10.1016/j.steroids.2004.10.002

- Choi J, Kim H, Jung H, et al. Anti-inflammatory and anti-aging effects of licorice extract. Food Sci Biotechnol. 2016;25(3):887-894. doi:10.1007/s10068-016-0125-4

- Fukai T, Marumo A, Kaitou K, Kanda T, Terada S, Nomura T. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002;71(12):1449-1463. doi:10.1016/s0024-3205(02)01854-9