Name: Garden of Wisdom Azelaic Acid 12% Serum (PAD)
Brand: Garden of Wisdom
Rating: 5 (6 reviews)

Water

Other Names: Aqua; H2O; Eau; Aqueous; Acqua

Function: Solvent

1. Definition Water:

Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.

2. Use:

Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.

3. Usage Water:

When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.

- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.

Potassium Azeloyl Diglycinate

Other Names: Potassium Azeloyl Diglycina; AZELOGLICINA; Potassium Azelaoyl Diglycinate

Function: Skin Conditioning

1. Definition Potassium Azeloyl Diglycinate:

Potassium Azeloyl Diglycinate is a water-soluble derivative of azelaic acid, a naturally occurring acid found in grains like barley, wheat, and rye. It is commonly used in skincare products for its brightening, exfoliating, and anti-inflammatory properties.

2. Use:

Potassium Azeloyl Diglycinate is primarily used in cosmetics and skincare products as a skin brightening agent. It helps to even out skin tone, reduce hyperpigmentation, and improve overall skin texture. Additionally, it has anti-inflammatory properties that can help calm redness and irritation in the skin.

3. Usage Potassium Azeloyl Diglycinate:

Potassium Azeloyl Diglycinate is typically found in serums, creams, and lotions targeted towards individuals looking to improve the appearance of their skin. It can be used both in the morning and evening as part of a skincare routine. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have sensitive skin or any concerns about using this ingredient.

4. References:

- Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin Cosmet Investig Dermatol. 2015;8:455-61. doi: 10.2147/CCID.S84765. Epub 2015 Aug 7. PMID: 26347269; PMCID: PMC4554394.

- Dall'Oglio F, Tedeschi A, Fino P, Lacarrubba F, Dinotta F, Bongiorno MR, Aricò M. A new topical azelaic acid foam: treatment for acne. Expert Opin Pharmacother. 2013 Nov;14(16):2271-9. doi: 10.1517/14656566.2013.844174. Epub 2013 Oct 9. PMID: 24102681.

- Grimes PE. The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. Dermatol Surg. 1999 Jan;25(1):18-22. doi: 10.1046/j.1524-4725.1999.08164.x. PMID: 9935084.

Glycerin

Other Names: Glycerine; Glycerin; Pflanzliches Glycerin; 1,2,3-Propanetriol

Function: Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

Sodium Lactate

Other Names: L-Sodium Lactate

Function: Humectant, pH adjusting agent, Exfoliant, Keratolytic

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

Leucidal Sf

Ingredient data is being updated. Please check back later.

Jojoba Protein

Ingredient data is being updated. Please check back later.

Silica Gel

Function: Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Opacifying, Anticaking Agent

1. Definition Silica Gel:

Silica gel is a desiccant commonly used in cosmetics to absorb excess moisture and prevent spoilage or degradation of products. It is a porous, granular form of silicon dioxide that is highly absorbent and non-toxic.

2. Use:

Silica gel is used in cosmetics to maintain the stability and shelf-life of products by absorbing excess moisture that can lead to bacterial growth, mold, or deterioration of active ingredients. It is commonly found in powdered cosmetics, such as loose powders, blushes, and eyeshadows, to prevent clumping and extend the product's lifespan.

3. Usage Silica Gel:

When using cosmetics containing silica gel, it is important to follow the manufacturer's instructions and guidelines. Avoid inhaling the powder or getting it in contact with the eyes, as it can cause irritation. Store products containing silica gel in a cool, dry place away from direct sunlight to prevent moisture absorption and maintain their effectiveness.

4. References:

- "Silica Gel: A Versatile Tool for the Manipulation of Drug Release in Topical Formulations" by J. C. Carreño-Gómez et al. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752184/)

- "Silica Gel: An Efficient and Versatile Catalyst for Organic Synthesis" by P. K. Parhi et al. (https://pubs.acs.org/doi/10.1021/acs.joc.8b02274)

- "Silica Gel: A Review of Its Adsorption Mechanism and Application in Water Treatment" by S. A. Al-Ghouti et al. (https://www.sciencedirect.com/science/article/abs/pii/S0043135410006307)

Carbomer

Other Names: Carboxypolymethylene; Carbopol; Cabomer

Function: Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

Dehydro Xanthan Gum

Function: Viscosity Controlling, Emulsion Stabilising, Film Forming, Hair Fixing

1. Definition Dehydro Xanthan Gum:

Dehydro Xanthan Gum is a modified version of xanthan gum, a natural polysaccharide produced by fermentation of sugar with a specific strain of bacteria. It is commonly used in cosmetics as a thickening agent, stabilizer, and emulsifier to improve the texture and consistency of products.

2. Use:

Dehydro Xanthan Gum is used in a wide range of cosmetic products, including creams, lotions, serums, and gels. It helps to create a smooth and creamy texture, enhances the spreadability of products, and provides a luxurious feel to the skin. Additionally, it can also help to stabilize emulsions and prevent the separation of oil and water phases in formulations.

3. Usage Dehydro Xanthan Gum:

When using Dehydro Xanthan Gum in cosmetics, it is important to follow the recommended usage levels provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 2% in formulations, depending on the desired viscosity and texture of the product. It is important to properly disperse the gum in the water phase of the formulation to ensure even distribution and optimal performance.

4. References:

- "Xanthan Gum in Cosmetics: Functions, Benefits, and Formulation Tips" by Lotioncrafter

- "Thickening Agents for Cosmetic Formulations" by Society of Cosmetic Chemists

- "Evaluation of the Safety and Efficacy of Xanthan Gum as a Cosmetic Ingredient" by International Journal of Cosmetic Science

Liposomes

1. Definition Liposomes:

Liposomes are small vesicles composed of phospholipid bilayers that are used as carriers for active ingredients in cosmetics. They have a structure similar to cell membranes, allowing them to easily fuse with the skin and deliver their payload effectively.

2. Use:

Liposomes are commonly used in cosmetics to improve the delivery of active ingredients to the skin. They can encapsulate both hydrophilic and hydrophobic compounds, allowing for a wider range of ingredients to be incorporated into skincare products. Liposomes can enhance the stability and bioavailability of active ingredients, leading to better results for the skin.

3. Usage Liposomes:

When using cosmetics containing liposomes, it is important to follow the instructions provided by the manufacturer. Generally, liposomal products should be applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use sunscreen during the day when using products containing liposomes, as they can increase the skin's sensitivity to UV radiation. Additionally, individuals with sensitive skin should perform a patch test before using products with liposomes to avoid any potential allergic reactions.

4. References:

- Lopes LB, Overcoming the cutaneous barrier with microemulsions. Pharmaceutics. 2014;6(1):52-77.

- Dragicevic-Curic N, et al. Lipid nanoparticles: an emerging approach for oral delivery of lipophilic drugs. Front Pharmacol. 2013;4:73.

- Du Plessis J, et al. The use of topical liposomes for enhancing drug delivery: mechanisms, formulation, and therapeutic applications. Front Pharmacol. 2018;9:1390.

Allantoin

Other Names: Glyoxyldiureide; Allantion

Function: Skin Protecting, Skin Conditioning, Soothing

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

Hyaluronic Acid

Other Names: Hyaluronate; Hyaluronic Acid; Biohyaluronic acid

Function: Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

EWG	CIR	Ingredient Name & Cosmetic Function	Notes
1	-	Water (Solvent)
1	-	Potassium Azeloyl Diglycinate (Skin Conditioning)
1 2	A	Glycerin (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant )	Good for dry skin Moisturizing
1 3	B	Sodium Lactate (Humectant, pH adjusting agent, Exfoliant, Keratolytic)
-	-	Leucidal Sf
-	-	Jojoba Protein
1	A	Silica Gel (Viscosity Controlling, Abrasive, Absorbent, Bulking Agent, Opacifying, Anticaking Agent)
1	A	Carbomer (Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Gel Forming)
1	A	Dehydro Xanthan Gum (Viscosity Controlling, Emulsion Stabilising, Film Forming, Hair Fixing)
1	-	Liposomes
1	A	Allantoin (Skin Protecting, Skin Conditioning, Soothing)	Good for sensitive skin Good for oily skin Moisturizing
1	A	Hyaluronic Acid (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising)	Promotes Wound Healing Moisturizing

Garden of Wisdom Azelaic Acid 12% Serum (PAD)

Ingredients

Analysis results of Ingredients

Ingredient List