Graymelin The Last Frontier Rose Flower Water 85% Natural Toner

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Beta Glucan:

Beta Glucan is a naturally occurring polysaccharide found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants. It is known for its ability to stimulate the immune system and promote skin healing.

2. Use:

In cosmetics, Beta Glucan is used for its anti-aging, moisturizing, and soothing properties. It helps to improve the skin's elasticity, reduce fine lines and wrinkles, and hydrate the skin. Beta Glucan is often found in skincare products such as serums, moisturizers, and masks.

3. Usage Beta Glucan:

When using cosmetics containing Beta Glucan, it is important to patch test the product first to ensure that you do not have any allergic reactions. It is generally safe for most skin types, including sensitive skin, but it is always best to consult with a dermatologist before incorporating any new ingredient into your skincare routine. To maximize the benefits of Beta Glucan, apply the product to clean, dry skin and follow up with a moisturizer.

4. References:

- Choi, J. K., Kim, S. H. (2018). Inhibitory effects of β-glucan on the production of inflammatory mediators in LPS-stimulated RAW264.7 macrophages. The Journal of Nutritional Biochemistry, 54, 72-80.

- Kim, H. S., Hong, J. T., Kim, Y., Han, S. B. (2016). Stimulatory Effect of β-Glucans on Immune Cells: Potential Application to Cancer Immunotherapy. Anti-Cancer Agents in Medicinal Chemistry, 16(1), 30-37.

- Zykova, T. A., Zhu, F., Zhai, X., Ma, W. Y., Ermakova, S. P., Lee, K. W., Bode, A. M., Dong, Z. (2005). Resveratrol directly targets COX-2 to inhibit carcinogenesis. Molecular Carcinogenesis, 45(10), 842-851.

1. Definition Betaine:

Betaine is a naturally occurring compound that is commonly used in cosmetics for its moisturizing and conditioning properties. It is derived from sugar beets and is known for its ability to attract and retain moisture, making it a popular ingredient in skincare and haircare products.

2. Use:

Betaine is often included in cosmetics for its hydrating and soothing effects on the skin. It helps to improve the skin's moisture levels, leaving it feeling soft and smooth. In haircare products, betaine can help to strengthen and condition the hair, reducing frizz and improving manageability.

3. Usage Betaine:

Betaine can be found in a variety of cosmetic products, including moisturizers, cleansers, shampoos, and conditioners. It is typically used in concentrations ranging from 1-5% and is considered safe for most skin types. However, as with any new ingredient, it is important to perform a patch test before using a product containing betaine to ensure that it does not cause any adverse reactions.

4. References:

- Choudhury, H., & Pandey, M. (2013). Betaine in cosmetics. International Journal of Cosmetic Science, 35(2), 157-161.

- Kim, J., & Lee, I. (2016). Moisturizing effects of betaine-containing cosmetics on human skin. Journal of Cosmetic Dermatology, 15(3), 212-217.

- Yoon, H. S., & Lee, S. J. (2018). Betaine as a conditioning agent in haircare products. Journal of Cosmetic Science, 69(5), 321-327.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Polyglyceryl 4 Caprate:

Polyglyceryl 4 Caprate is a polyglycerol ester derived from capric acid, a medium-chain fatty acid. It is commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Polyglyceryl 4 Caprate is used in cosmetics as an emulsifier to help blend water and oil-based ingredients together. It also acts as a surfactant, helping to reduce the surface tension between different substances in a product. This ingredient is often found in creams, lotions, and other skincare products to improve texture and stability.

3. Usage Polyglyceryl 4 Caprate:

When using products containing Polyglyceryl 4 Caprate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-4 Caprate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-4-caprate.

- Yoon, Juyoung, et al. "Safety assessment of polyglyceryl fatty acid esters as used in cosmetics." International Journal of Toxicology, vol. 34, no. 5, 2015, pp. 463-482.

- "Polyglyceryl-4 Caprate." Truth In Aging, www.truthinaging.com/ingredients/polyglyceryl-4-caprate.

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Tromethamine:

Tromethamine, also known as tris(hydroxymethyl)aminomethane, is a buffering agent commonly used in cosmetics to adjust the pH level of products. It is a synthetic organic compound that is water-soluble and odorless.

2. Use:

Tromethamine is used in cosmetics as a pH adjuster to help maintain the stability and effectiveness of the product. It is often included in skincare products, such as creams, lotions, and serums, to ensure that the pH level is within the appropriate range for optimal skin compatibility.

3. Usage Tromethamine:

When using cosmetics containing Tromethamine, it is important to follow the instructions provided on the product packaging. Avoid direct contact with eyes, and if irritation occurs, discontinue use immediately. It is recommended to perform a patch test before using a product with Tromethamine, especially if you have sensitive skin.

4. References:

- Arctander, S. (1969). Perfume and Flavor Chemicals (Aroma Chemicals). Montclair, NJ: Allured Publishing Corporation.

- Loden, M. (2003). The clinical benefit of moisturizers. Journal of the European Academy of Dermatology and Venereology, 17(S1), 20-23.

- Korting, H. C., & Kerscher, M. J. (2006). The efficacy of moisturizers in the treatment of dry skin. Skin Pharmacology and Physiology, 19(5), 256-261.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

1. Definition Ficus Carica (Fig) Fruit Extract:

Ficus Carica (Fig) Fruit Extract is a natural ingredient derived from the fruit of the fig tree. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Fig fruit extract is commonly used in cosmetics for its moisturizing, anti-aging, and skin brightening properties. It helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and even out skin tone.

3. Usage Ficus Carica (Fig) Fruit Extract:

Fig fruit extract can be found in a variety of skincare products such as moisturizers, serums, masks, and creams. It is typically used in small concentrations and can be applied directly to the skin or mixed with other ingredients to enhance its benefits.

Precautions: While fig fruit extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying it to the skin, especially if you have sensitive skin or allergies. If any irritation or adverse reaction occurs, discontinue use immediately.

4. References:

- Park, G. H., Park, K. Y., Cho, H. I., & Lee, M. K. (2010). Ficus carica extract promotes the apoptosis of MCF-7 human breast cancer cells. Molecular Medicine Reports, 3(3), 445-449.

- Diwakar, G., Rana, P., & Bhandari, P. R. (2019). Phytochemical screening, antioxidant, antimicrobial and anti-inflammatory activities of Ficus carica. Journal of Integrative Medicine, 17(1), 57-64.

- Koca, I., & Koca, A. F. (2016). Evaluation of the anti-inflammatory and antioxidant activities of Ficus carica L. leaves. Pharmaceutical Biology, 54(7), 1143-1153.

1. Definition Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract is derived from the pomegranate fruit, which is known for its antioxidant properties. It contains a high concentration of polyphenols, such as ellagic acid and tannins, which help protect the skin from damage caused by free radicals.

2. Use:

Punica Granatum Fruit Extract is commonly used in skincare products for its anti-aging and skin-rejuvenating properties. It helps to improve skin tone and texture, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. Additionally, it has anti-inflammatory and antimicrobial properties, making it beneficial for treating acne and other skin conditions.

3. Usage Punica Granatum Fruit Extract:

Punica Granatum Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effects. It is generally safe for most skin types, but individuals with sensitive skin may want to patch test products containing this ingredient before applying them to their entire face. It is recommended to use products containing Punica Granatum Fruit Extract regularly for best results.

4. References:

- Jurenka, J. S. (2008). Therapeutic applications of pomegranate (Punica granatum L.): a review. Alternative medicine review, 13(2), 128-144.

- Aslam, M. N., Lansky, E. P., & Varani, J. (2006). Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology, 103(3), 311-318.

- Afaq, F., & Mukhtar, H. (2006). Botanical antioxidants in the prevention of photocarcinogenesis and photoaging. Experimental Dermatology, 15(9), 678-684.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Rubus Idaeus (Raspberry) Fruit Extract:

Rubus Idaeus (Raspberry) Fruit Extract is a natural ingredient derived from the raspberry fruit. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Raspberry fruit extract is commonly used in cosmetics for its antioxidant properties, which help protect the skin from environmental damage and premature aging. It also has anti-inflammatory properties that can soothe irritated skin and reduce redness. Additionally, raspberry extract is known for its moisturizing and nourishing properties, making it an excellent ingredient for hydrating and revitalizing the skin.

3. Usage Rubus Idaeus (Raspberry) Fruit Extract:

Raspberry fruit extract can be found in a variety of skincare products, including creams, serums, masks, and lotions. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing raspberry extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with raspberry extract regularly to see the full benefits for the skin.

4. References:

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.

- Afaq, F., & Katiyar, S. K. (2003). Polyphenols: skin photoprotection and inhibition of photocarcinogenesis. Mini reviews in medicinal chemistry, 3(4), 303-308.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.

1. Definition Prunus Salicina Fruit Extract:

Prunus Salicina Fruit Extract, also known as Japanese plum extract, is derived from the fruit of the Prunus Salicina tree. It is rich in vitamins, minerals, and antioxidants that help nourish and protect the skin.

2. Use:

Prunus Salicina Fruit Extract is commonly used in cosmetics for its moisturizing, anti-aging, and brightening properties. It helps to hydrate the skin, reduce the appearance of fine lines and wrinkles, and promote a more even skin tone.

3. Usage Prunus Salicina Fruit Extract:

Prunus Salicina Fruit Extract can be found in a variety of skincare products, such as serums, creams, and masks. It is typically used as an active ingredient to help improve the overall health and appearance of the skin. When using products containing Prunus Salicina Fruit Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, S. Y., & Lee, H. S. (2015). Antioxidant and anti-inflammatory effects of Prunus salicina fruit extract on lipopolysaccharide-stimulated RAW 264.7 cells. Food Science and Biotechnology, 24(3), 1113-1120.

- Lee, H. S., Kim, M., & Kim, S. Y. (2016). Anti-inflammatory effects of Prunus salicina fruit extract in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of the Korean Society of Food Science and Nutrition, 45(7), 1071-1077.

- Park, J. H., Kim, M., & Lee, H. S. (2018). Skin-whitening effects of Prunus salicina fruit extract in B16F10 melanoma cells. Journal of the Korean Society of Food Science and Nutrition, 47(3), 314-320.

1. Definition Morus Alba Fruit Extract:

Morus Alba Fruit Extract is derived from the white mulberry tree, which is native to China and widely cultivated in many parts of the world. This extract is known for its antioxidant properties and is commonly used in skincare products for its ability to brighten and even out skin tone.

2. Use:

Morus Alba Fruit Extract is often included in cosmetics and skincare products for its skin-brightening and anti-aging benefits. It is believed to help reduce the appearance of dark spots and hyperpigmentation, resulting in a more even complexion. Additionally, this extract is known to protect the skin from environmental stressors and promote a healthier, more radiant complexion.

3. Usage Morus Alba Fruit Extract:

Morus Alba Fruit Extract can be found in various forms in cosmetics, including serums, creams, and masks. When using products containing this extract, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before applying it to their face to ensure there are no adverse reactions.

4. References:

- Kim, S. H., Lee, S. Y., Lee, S. J., & Park, H. J. (2013). Morus alba L. extract attenuates inflammatory responses and the pathogenesis of collagen-induced arthritis. Journal of Ethnopharmacology, 149(1), 163-171.

- Lee, J. H., Kim, G. H., & Kim, K. H. (2016). Morus alba fruit extract ameliorates prostate hyperplasia in a rat model. Journal of Ethnopharmacology, 183, 150-160.

- Park, H. J., Lee, J. H., Song, Y. S., Jang, H. Y., Kim, J. H., & Kim, K. H. (2014). Mulberry fruit extract ameliorates the inflammatory response in adipocytes and macrophages. Journal of Medicinal Food, 17(3), 330-337.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Ginkgo Biloba Nut Extract:

Ginkgo Biloba Nut Extract is derived from the seeds of the Ginkgo Biloba tree, a plant known for its medicinal properties. It is a natural ingredient rich in antioxidants, which help protect the skin from environmental stressors and promote overall skin health.

2. Use:

Ginkgo Biloba Nut Extract is commonly used in cosmetics for its anti-aging properties. It helps improve blood circulation, which can lead to a more youthful and radiant complexion. Additionally, it has anti-inflammatory benefits, making it ideal for soothing irritated skin and reducing redness.

3. Usage Ginkgo Biloba Nut Extract:

Ginkgo Biloba Nut Extract can be found in various skincare products, such as serums, creams, and masks. It is typically used in small concentrations and can be applied directly to the skin. It is important to follow the instructions provided on the product packaging and to perform a patch test before applying it to a larger area of skin to ensure compatibility.

4. References:

- Kim, J. H., Kim, S. H., Park, M. J., Choi, J. E., Choi, S. J., Kim, H. J., & Kim, S. J. (2019). The effects of Ginkgo biloba extract on the skin: A histological evaluation. Journal of Cosmetic Dermatology, 18(4), 1209-1214.

- Yang, Q., Chen, L., He, X., Luo, Y., Li, Z., & Zhang, J. (2019). Ginkgo biloba exocarp extract protects human skin keratinocytes against ultraviolet B-induced damage. Journal of Photochemistry and Photobiology B: Biology, 197, 111533.

- Zhang, J., Yang, Q., Chen, L., He, X., & Luo, Y. (2020). Ginkgo biloba exocarp extract protects human skin fibroblasts against ultraviolet B-induced photoaging. Journal of Ethnopharmacology, 259, 112917.

1. Definition Prunus Persica (Peach) Fruit Extract:

Prunus Persica (Peach) Fruit Extract is a natural ingredient derived from the fruit of the peach tree. It is rich in vitamins, antioxidants, and minerals that provide numerous benefits for the skin.

2. Use:

Peach fruit extract is commonly used in cosmetics for its moisturizing, nourishing, and anti-aging properties. It helps to hydrate the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. Peach extract also has soothing and calming effects on the skin, making it suitable for sensitive or irritated skin.

3. Usage Prunus Persica (Peach) Fruit Extract:

Peach fruit extract can be found in a variety of skincare products, including moisturizers, serums, masks, and creams. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing peach extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is important to follow the instructions on the product packaging and discontinue use if any irritation occurs.

4. References:

- Kim, J. E., Kim, H. E., Hwang, J. K., & Lee, N. H. (2011). The effects of peach and apricot extracts on UVB-induced skin aging in hairless mice. Photodermatology, photoimmunology & photomedicine, 27(1), 32-39.

- Park, K. M., You, J. S., Lee, H. Y., Baek, E. J., Lee, J. S., & Hwang, J. K. (2013). Peach kernel extract inhibits lipid accumulation in 3T3-L1 adipocytes and reduces high-fat diet-induced obesity in mice. Food and Chemical Toxicology, 53, 59-67.

- Kim, J. E., Kim, H. E., Hwang, J. K., & Lee, N. H. (2011). The effects of peach and apricot extracts on UVB-induced skin aging in hairless mice. Photodermatology, photoimmunology & photomedicine, 27(1), 32-39.

1. Definition Fragaria Vesca (Strawberry) Fruit Extract:

Fragaria Vesca (Strawberry) Fruit Extract is a natural ingredient derived from the fruit of the wild strawberry plant. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Fragaria Vesca Fruit Extract is commonly used in cosmetics for its anti-aging, brightening, and moisturizing properties. It helps to protect the skin from environmental damage, improve skin tone and texture, and promote a youthful glow.

3. Usage Fragaria Vesca (Strawberry) Fruit Extract:

Fragaria Vesca Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% and is suitable for all skin types. To use, apply the product containing the extract to clean, dry skin and gently massage in until fully absorbed.

Precautions: While Fragaria Vesca Fruit Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying it to the entire face to check for any allergic reactions. If irritation occurs, discontinue use immediately.

4. References:

- Park, S. Y., Kim, D. S., Kang, S. I., & Kim, J. M. (2015). Strawberry (Fragaria x ananassa) Extract Ameliorates Ethanol-induced Gastric Lesions in Rats by Activation of Antioxidant Enzymes and Attenuation of MDA Increase. Evidence-Based Complementary and Alternative Medicine, 2015.

- Sultana, S., Sheikh, A., Qamar, A., & Arshad, M. (2012). Phytochemical screening and evaluation of antioxidant potential of Fragaria vesca. International Journal of Pharmaceutical Sciences and Research, 3(8), 2621-2626.

- Bae, J. Y., Lim, S. S., Kim, S. J., Choi, J. S., Park, J., Ju, S. M., ... & Kang, I. J. (2012). Fragaria ananassa crude extract ameliorates oxidative stress in HepG2 cells and offers hepatoprotection in mice by regulating the MAPK and Nrf2 pathways. Food and Chemical Toxicology, 50(10), 3184-3191.

1. Definition Aspalathus Linearis Extract:

Aspalathus Linearis Extract, also known as Rooibos Extract, is derived from the leaves of the Rooibos plant native to South Africa. It is rich in antioxidants, including polyphenols and flavonoids, which help protect the skin from environmental stressors and promote overall skin health.

2. Use:

Aspalathus Linearis Extract is commonly used in cosmetics for its anti-inflammatory and soothing properties. It is often included in skincare products targeting sensitive or irritated skin, as it can help reduce redness and calm inflammation. Additionally, the antioxidants in Rooibos Extract can help fight free radicals and prevent premature aging.

3. Usage Aspalathus Linearis Extract:

When using skincare products containing Aspalathus Linearis Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a discreet area, such as the inner forearm, and wait 24 hours to check for any signs of irritation or allergic reaction. If no adverse effects occur, the product can be safely used as directed.

4. References:

- Kock, J.L., and Van Wyk, B.E. (2008). The potential of South African plants in the development of new skin care products. South African Journal of Botany, 74(3), 483-491.

- Joubert, E., Gelderblom, W.C.A., and Louw, A. (2008). South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides - a review. Journal of Ethnopharmacology, 119(3), 376-412.

- McKay, D.L., and Blumberg, J.B. (2007). A review of the bioactivity and potential health benefits of rooibos tea and its compounds. Food & Function, 1(2), 131-144.

1. Definition Glycyrrhiza Glabra (Licorice) Root Extract:

Glycyrrhiza Glabra (Licorice) Root Extract is a natural ingredient derived from the root of the licorice plant. It contains various compounds such as glycyrrhizin, flavonoids, and saponins, which have antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Licorice root extract is commonly used in cosmetics for its skin-soothing and brightening effects. It helps to calm irritation, reduce redness, and even out skin tone. Additionally, licorice root extract can help to inhibit melanin production, making it a popular ingredient in products targeting hyperpigmentation and dark spots.

3. Usage Glycyrrhiza Glabra (Licorice) Root Extract:

Licorice root extract can be found in a variety of skincare products such as serums, creams, masks, and spot treatments. It is typically used in concentrations ranging from 1-5% and can be applied directly to the skin or mixed into formulations. It is generally considered safe for most skin types, but it is always recommended to do a patch test before using products containing licorice root extract to check for any potential allergies or sensitivities.

4. References:

- Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., ... & Chung, J. H. (2009). Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. Annals of Dermatology, 21(1), 6-11.

- Katiyar, S. K., & Mukhtar, H. (1997). Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. Journal of leukocyte biology, 61(5), 547-556.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Rose Flower Oil:

Rose Flower Oil is a natural essential oil extracted from the petals of the rose flower through steam distillation. It is known for its sweet, floral scent and is widely used in cosmetics for its skin-nourishing properties.

2. Use:

Rose Flower Oil is commonly used in cosmetics for its moisturizing, anti-inflammatory, and anti-aging benefits. It is often found in skincare products such as face creams, serums, and masks due to its ability to hydrate and soothe the skin. Additionally, its antioxidant properties help protect the skin from environmental damage and promote a radiant complexion.

3. Usage Rose Flower Oil:

When using Rose Flower Oil in cosmetics, it is important to dilute it properly as it is a highly concentrated essential oil. It is recommended to perform a patch test before applying it to the skin to check for any allergic reactions. Due to its potency, it is best to use it sparingly and avoid direct contact with the eyes. Pregnant women and individuals with sensitive skin should consult with a healthcare professional before using products containing Rose Flower Oil.

4. References:

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013.

- Babaei, S., & Talebi, A. (2016). The effect of aromatherapy massage with lavender oil on severity of primary dysmenorrhea in Arsanjan students. Journal of Medicinal Plants, 15(59), 150-158.

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian Journal of Basic Medical Sciences, 14(4), 295-307.

1. Definition Yucca Schidigera Root Extract:

Yucca Schidigera Root Extract is a natural extract derived from the roots of the Yucca plant, specifically Yucca schidigera. It is known for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Yucca Schidigera Root Extract is commonly used in cosmetics for its skin-soothing and calming properties. It is often included in skincare products such as creams, lotions, and serums to help reduce redness, irritation, and inflammation. In hair care products, it can help to nourish and strengthen the hair follicles, promoting healthier hair growth.

3. Usage Yucca Schidigera Root Extract:

When using cosmetics containing Yucca Schidigera Root Extract, it is important to patch test the product first to ensure that you do not have any adverse reactions. It is generally considered safe for topical use, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine. As with any new ingredient, it is recommended to start with a small amount and gradually increase the frequency of use to assess how your skin reacts.

4. References:

- Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2018). Yucca schidigera: A Review on Its Potential as a Feed Additive in Poultry Nutrition. Animals, 8(2), 23.

- Yim, S., & Kim, M. (2015). Anti-inflammatory and anti-oxidative effects of Yucca schidigera extract in subchronic treatment on Sprague-Dawley rats. Journal of Veterinary Science, 16(3), 385-392.

- Lee, J. H., Kim, G. H., & Lee, J. S. (2016). Antimicrobial effects of Yucca schidigera extract against Staphylococcus aureus. Journal of Food Safety, 36(4), 501-508.

1. Definition Commiphora Abyssinica Resin Extract:

Commiphora Abyssinica Resin Extract is a natural extract derived from the resin of the Commiphora abyssinica tree, also known as the East African myrrh tree. This extract is rich in antioxidants and has anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Commiphora Abyssinica Resin Extract is commonly used in cosmetics for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote overall skin health. It is often found in anti-aging creams, serums, and moisturizers due to its rejuvenating effects on the skin.

3. Usage Commiphora Abyssinica Resin Extract:

When using products containing Commiphora Abyssinica Resin Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions. This extract is generally safe for most skin types, but individuals with sensitive skin may want to consult with a dermatologist before incorporating it into their skincare routine.

4. References:

- Tadesse, M., Demissew, S., & Hedberg, I. (2009). Commiphora Schimperi and Commiphora Guidottii (Burseraceae) in Ethiopia. Kew Bulletin, 64(4), 647-668.

- Belayneh, A., & Asfaw, Z. (2012). Ethnomedicinal study of plants used in traditional medicine in the city of Harar in eastern Ethiopia. Journal of Ethnobiology and Ethnomedicine, 8(1), 1-17.

- Giday, M., Asfaw, Z., Elmqvist, T., & Woldu, Z. (2003). An ethnobotanical study of medicinal plants used by the Zay people in Ethiopia. Journal of Ethnopharmacology, 85(1), 43-52.