ProDerma Acnevest Acne Gel

1. Definition Tartaric Acid:

Tartaric acid is a naturally occurring organic acid found in many plants, particularly grapes. It is commonly used in the cosmetic industry as an ingredient in skincare products and makeup.

2. Use:

Tartaric acid is used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture of the skin. It is often found in facial peels, masks, and anti-aging products.

3. Usage Tartaric Acid:

When using cosmetics containing tartaric acid, it is important to follow the instructions provided by the manufacturer. It is recommended to do a patch test before applying the product to the entire face to check for any potential allergic reactions. Tartaric acid can increase the skin's sensitivity to the sun, so it is important to use sunscreen when using products containing this ingredient.

4. References:

- Katsarou A, Gortzi O, Mantzourani I, et al. Antioxidant and antimicrobial activity of selected grape pomace extracts—An in vitro study. Antioxidants. 2019;8(7):191. doi:10.3390/antiox8070191

- Del Pozo-Acebo L, Martínez-Sanz M, Lizarraga D, et al. Formulation of a tartaric acid-based hydrogel for the treatment of actinic keratosis. Pharmaceutics. 2019;11(9):451. doi:10.3390/pharmaceutics11090451

- Chaudhari SP, Tamhankar BM, Sonawane KB, et al. Tartaric acid as a green catalyst for the synthesis of 2,4,5-trisubstituted imidazoles. Synth Commun. 2019;49(14):1767-1774. doi:10.1080/00397911.2019.1630254

1. Definition Peg 8:

Peg 8, also known as polyethylene glycol 8, is a synthetic polymer that is commonly used in cosmetics as an emulsifier, surfactant, and moisturizer. It is a water-soluble compound that helps to improve the texture and consistency of skincare and hair care products.

2. Use:

Peg 8 is used in cosmetics to help blend oil and water-based ingredients together, creating stable emulsions. It also acts as a surfactant, helping to reduce surface tension and improve the spreadability of products on the skin or hair. Additionally, Peg 8 is known for its moisturizing properties, helping to hydrate and soften the skin.

3. Usage Peg 8:

Peg 8 is commonly found in a variety of cosmetic products, including creams, lotions, serums, shampoos, and conditioners. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is important to patch test products containing Peg 8 before applying them to larger areas of the skin.

4. References:

- S. H. Yoon, H. J. Lee, S. J. Yoon, S. M. Choi, "Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use," International Journal of Toxicology, vol. 29, no. 1, 2010.

- A. L. Silva, J. F. L. Gomes, M. A. S. Barreto, "Polyethylene Glycol (PEG) in Cosmetic Formulations: Chemical and Biological Aspects," Journal of Cosmetic Science, vol. 69, no. 1, 2018.

- M. S. Roberts, K. Y. Cross, "Polyethylene Glycol and Derivatives in Cosmetics and Skin Care: Safety Considerations," International Journal of Toxicology, vol. 31, no. 1, 2012.

1. Definition Biotin:

Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin, hair, and nails. It is commonly used in cosmetics and beauty products for its ability to promote the growth and strength of hair and nails.

2. Use:

Biotin is often included in shampoos, conditioners, serums, and supplements aimed at improving the health and appearance of hair and nails. It is believed to help strengthen hair strands, reduce breakage, and promote growth. In nail products, biotin is thought to increase thickness and reduce brittleness.

3. Usage Biotin:

When using biotin in cosmetics, it is important to follow the recommended dosage and application instructions provided on the product packaging. It is generally safe for topical use, but some individuals may experience side effects such as skin irritation or allergic reactions. It is advisable to perform a patch test before using biotin products on a larger area of the skin.

4. References:

- Trüeb, R. M. (2016). Serum Biotin Levels in Women Complaining of Hair Loss. International Journal of Trichology, 8(2), 73–77. https://doi.org/10.4103/0974-7753.188040

- Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin Appendage Disorders, 3(3), 166–169. https://doi.org/10.1159/000462981

- Lipner, S. R., & Scher, R. K. (2017). Biotin for the Treatment of Nail Disease: What is the Evidence? Journal of Dermatological Treatment, 28(1), 16–17. https://doi.org/10.1080/09546634.2016.1276528

1. Definition Sodium Ascorbyl Phosphate:

Sodium Ascorbyl Phosphate is a stable derivative of Vitamin C, commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Sodium Ascorbyl Phosphate is often included in cosmetic formulations to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to inhibit melanin production, making it a popular ingredient in products designed to fade dark spots and hyperpigmentation.

3. Usage Sodium Ascorbyl Phosphate:

When using skincare products containing Sodium Ascorbyl Phosphate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of product is applied to clean, dry skin in the morning or evening, depending on the specific product recommendations. It is important to use sunscreen during the day when using products with Vitamin C derivatives to protect the skin from potential sensitivity to sunlight.

4. References:

- Telang, P. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Al-Niaimi, F., & Chiang, N. Y. Z. (2017). Topical Vitamin C and the skin: Mechanisms of action and clinical applications. The Journal of clinical and aesthetic dermatology, 10(7), 14–17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/

1. Definition Ascorbyl Glucoside:

Ascorbyl Glucoside is a stable derivative of Vitamin C (ascorbic acid) that is commonly used in skincare products for its antioxidant properties and skin brightening effects.

2. Use:

Ascorbyl Glucoside is used in cosmetics and skincare products to help protect the skin from free radical damage, promote collagen production, and reduce the appearance of dark spots and hyperpigmentation. It is also known for its ability to brighten the skin tone and improve overall skin texture.

3. Usage Ascorbyl Glucoside:

Ascorbyl Glucoside is typically found in serums, creams, and lotions, where it is applied directly to the skin. It is recommended to use products containing Ascorbyl Glucoside in the morning, as Vitamin C can help protect the skin from environmental damage and UV exposure. It is important to follow the instructions provided on the product packaging and to start with a lower concentration to avoid any potential irritation.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143–146. https://doi.org/10.4103/2229-5178.110593

- Pullar, J. M., Carr, A. C., & Vissers, M. (2017). The roles of Vitamin C in skin health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832. https://doi.org/10.1111/j.0022-202X.2005.23768.x

1. Definition Anthemis Nobilis (Chamomile) Extract:

Anthemis Nobilis (Chamomile) Extract is a natural ingredient derived from the flowers of the chamomile plant. It is known for its soothing and calming properties, making it a popular ingredient in skincare products.

2. Use:

Chamomile extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and antibacterial properties. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation.

3. Usage Anthemis Nobilis (Chamomile) Extract:

Chamomile extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in small concentrations to avoid any potential irritation. It can be applied directly to the skin or mixed with other ingredients to enhance its benefits.

Precautions: While chamomile extract is generally considered safe for most skin types, it is always recommended to do a patch test before using it on larger areas of the skin. Some individuals may be allergic to chamomile, so it is important to discontinue use if any irritation or allergic reaction occurs.

4. References:

- Srivastava, J.K., Shankar, E. & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- McKay, D.L., & Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

- Miraj, S., & Alesaeidi, S. (2016). A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electronic Physician, 8(9), 3024-3031.

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Imidazolidinyl Urea:

Imidazolidinyl Urea is a synthetic preservative that is commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde, which acts as a preservative.

2. Use:

Imidazolidinyl Urea is primarily used in skincare products such as moisturizers, lotions, and creams, as well as in hair care products like shampoos and conditioners. It is also found in makeup products like foundations and mascaras. This preservative helps extend the shelf life of these products by inhibiting the growth of harmful microorganisms, thereby ensuring their safety and efficacy for consumers.

3. Usage Imidazolidinyl Urea:

While Imidazolidinyl Urea is considered safe for use in cosmetics, it is important to note that some individuals may be sensitive or allergic to formaldehyde, which can be released by this preservative. Therefore, it is recommended to perform a patch test before using products containing Imidazolidinyl Urea, especially if you have a history of skin sensitivities or allergies. Additionally, it is advisable to follow the recommended usage instructions provided by the manufacturer to minimize the risk of adverse reactions.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Imidazolidinyl Urea. International Journal of Toxicology. 1996;15(Suppl 1):123-141.

- Personal Care Products Council. Imidazolidinyl Urea. Accessed from: https://www.cosmeticsinfo.org/ingredient/imidazolidinyl-urea

- U.S. Food and Drug Administration. CFR - Code of Federal Regulations Title 21. Accessed from: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.19

1. Definition Sodium Hydroxide:

Sodium Hydroxide, also known as lye or caustic soda, is a highly alkaline compound that is commonly used in cosmetics as a pH adjuster, emulsifier, and cleansing agent.

2. Use:

Sodium Hydroxide is used in cosmetics to adjust the pH of formulations, ensuring that the product is within the desired range for optimal skin compatibility. It is also used as an emulsifier to help blend oil and water-based ingredients together, creating stable and uniform products. Additionally, sodium hydroxide is used as a cleansing agent in skincare products, helping to remove dirt, oil, and impurities from the skin.

3. Usage Sodium Hydroxide:

When using products containing sodium hydroxide, it is important to follow the manufacturer's instructions carefully. Avoid direct contact with the eyes, as it can cause irritation or burns. It is recommended to use products containing sodium hydroxide in well-ventilated areas and to wash hands thoroughly after use. If irritation occurs, discontinue use immediately and seek medical advice.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2013). Final report on the safety assessment of sodium hydroxide. International Journal of Toxicology, 32(1), 59S-80S.

- Personal Care Products Council. (2020). Sodium Hydroxide. Retrieved from https://www.personalcarecouncil.org/ingredient-info/sodium-hydroxide/

- National Center for Biotechnology Information. (2021). Sodium Hydroxide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydroxide

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133