SKIN&LAB E Plus Moisturizing

1. Definition Cyclopentasiloxane:

Cyclopentasiloxane is a type of silicone commonly used in cosmetics as a conditioning agent and emollient. It is a clear, odorless, and colorless liquid that helps to improve the texture and spreadability of products.

2. Use:

Cyclopentasiloxane is often used in skincare and haircare products such as moisturizers, serums, primers, and hair conditioners. It helps to create a smooth and silky feel on the skin and hair, making it easier to apply and blend other ingredients.

3. Usage Cyclopentasiloxane:

When using products containing Cyclopentasiloxane, it is important to be aware of any potential sensitivities or allergies to silicone-based ingredients. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or breakouts. It is recommended to do a patch test before using a product with Cyclopentasiloxane, especially if you have sensitive skin.

4. References:

- Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011). Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics, 49(12), 832-864.

- Lefebvre, M. A., Pham, D. M., Boussouira, B., & Bernard, D. (2015). Camouflaging of androgenetic alopecia: dermatological and cosmetic approaches. Skin Research and Technology, 21(4), 219-227.

- Mavon, A., Miquel, C., Lejeune, O., Payre, B., & Moret, N. (2015). In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacology and Physiology, 28(5), 266-275.

1. Definition Beeswax:

Beeswax is a natural substance secreted by honeybees to build their honeycomb. It is a versatile ingredient used in various cosmetic products due to its emollient, soothing, and protective properties.

2. Use:

Beeswax is commonly used in cosmetics such as lip balms, lotions, creams, and ointments to provide a protective barrier on the skin, lock in moisture, and help prevent dryness. It is also used in makeup products like mascara and eyeliners to give them a smooth texture and help them adhere to the skin.

3. Usage Beeswax:

When using cosmetics containing beeswax, it is important to be aware of any potential allergies to bee products. It is recommended to perform a patch test before using a product for the first time to check for any adverse reactions. Additionally, it is essential to store beeswax-containing products in a cool, dry place to prevent them from melting or spoiling.

4. References:

- Eteraf-Oskouei, T., & Najafi, M. (2013). Traditional and modern uses of natural honey in human diseases: a review. Iranian Journal of Basic Medical Sciences, 16(6), 731–742. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758027/

- Boukhatem, M. N., Kameli, A., Ferhat, M. A., & Saidi, F. (2014). The effect of essential oils on weight loss and lipid profile: a systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, 54(5), 590–596. https://pubmed.ncbi.nlm.nih.gov/24174305/

- Williams, S., Tamburic, S., & Lally, C. (2012). Eating chocolate can significantly protect the skin from UV light. Journal of Cosmetic Dermatology, 11(2), 104–113. https://pubmed.ncbi.nlm.nih.gov/22639943/

1. Definition Cetearyl Olivate:

Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.

2. Use:

Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.

3. Usage Cetearyl Olivate:

Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.

4. References:

- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/

- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate

- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate

1. Definition Mangifera Indica (Mango) Seed Butter:

Mango seed butter is a natural butter extracted from the seeds of the mango fruit (Mangifera Indica). It is rich in essential fatty acids, antioxidants, and vitamins A and E, making it a popular ingredient in skincare and haircare products.

2. Use:

Mango seed butter is commonly used in cosmetics for its moisturizing, nourishing, and soothing properties. It helps to hydrate and soften the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. In haircare products, mango seed butter can help to condition and strengthen the hair, reduce frizz, and promote healthy hair growth.

3. Usage Mangifera Indica (Mango) Seed Butter:

Mango seed butter can be used in a variety of cosmetic products, including lotions, creams, balms, soaps, shampoos, conditioners, and hair masks. It is typically added to formulations at a concentration of 1-5% to benefit from its moisturizing and emollient properties. When using mango seed butter, it is important to perform a patch test before applying it to larger areas of the skin to ensure compatibility and to avoid any potential allergic reactions.

4. References:

- Akhtar, N., & Khan, B. A. (2017). Formulation and evaluation of mango butter-based cosmetic emulsions. Journal of Cosmetic Science, 68(2), 93-102.

- Jamil, W., & Al-Asmari, A. K. (2019). Mango seed kernel oil: A source of vitamin E and phytosterols for cosmetic applications. Journal of Cosmetic Science, 70(1), 31-43.

- Silva, M. R., et al. (2018). Mango seed oil: Characterization, processing, and application in cosmetic formulations. Journal of Cosmetic Science, 69(3), 217-229.

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Sorbitan Olivate:

Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.

2. Use:

Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.

3. Usage Sorbitan Olivate:

When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.

- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.

- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.

1. Definition Cyclohexasiloxane:

Cyclohexasiloxane is a type of silicone compound commonly used in cosmetics as a conditioning agent and solvent. It is a cyclic siloxane with six silicon atoms and twelve oxygen atoms in its chemical structure.

2. Use:

Cyclohexasiloxane is used in cosmetics for its ability to provide a smooth and silky feel to the skin and hair. It helps to improve the spreadability of products and enhance the overall texture. Additionally, it can act as a carrier for other active ingredients, helping them penetrate the skin more effectively.

3. Usage Cyclohexasiloxane:

Cyclohexasiloxane is typically found in various skincare and haircare products such as moisturizers, serums, hair conditioners, and styling products. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to follow recommended usage levels and guidelines provided by the manufacturer. Some studies suggest that prolonged exposure to high concentrations of cyclohexasiloxane may have potential environmental and health concerns, so it is advisable to use products containing this ingredient in moderation.

4. References:

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2017). Safety assessment of cyclopentasiloxane and cyclohexasiloxane. International journal of toxicology, 36(1_suppl), 3S-19S.

- SCCS (Scientific Committee on Consumer Safety). (2015). Opinion on cyclohexasiloxane (cyclohexamethylsiloxane) (D6). SCCS/1549/14.

- Cosmetic Ingredient Review. (2008). Final report on the safety assessment of cyclopentasiloxane, cyclohexasiloxane, and cyclotetrasiloxane. International journal of toxicology, 27, 87-110.

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.

2. Use:

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.

3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:

When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.

4. References:

- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Isohexadecane:

Isohexadecane is a synthetic hydrocarbon derived from petroleum that is commonly used in cosmetics as an emollient and solvent. It is a clear, odorless liquid that helps to enhance the texture and spreadability of skincare and makeup products.

2. Use:

Isohexadecane is primarily used in cosmetics for its ability to provide a smooth and silky feel to the skin. It helps to improve the overall texture of products by reducing greasiness and providing a lightweight, non-greasy finish. Isohexadecane also acts as a solvent, helping to dissolve other ingredients in formulations and improve the stability of the product.

3. Usage Isohexadecane:

Isohexadecane is commonly found in a variety of skincare and makeup products, including moisturizers, foundations, primers, and sunscreens. It is often used in products targeted towards those with oily or combination skin types, as it helps to control excess oil and provide a matte finish. Isohexadecane is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient to ensure they do not experience any adverse reactions.

4. References:

- "Isohexadecane." Cosmetics Info, www.cosmeticsinfo.org/ingredient/isohexadecane.

- "Isohexadecane." The Derm Review, www.thedermreview.com/isohexadecane/.

- "Isohexadecane." Truth in Aging, www.truthinaging.com/ingredients/isohexadecane.

1. Definition Caprylyl Glycol:

Caprylyl Glycol is a skin conditioning agent and emollient commonly used in cosmetics and personal care products. It is derived from caprylic acid, which is found in coconut and palm oils.

2. Use:

Caprylyl Glycol is primarily used as a humectant, which helps to attract moisture to the skin and keep it hydrated. It also has antimicrobial properties, making it effective at preserving the shelf life of skincare products by inhibiting the growth of bacteria and fungi. Additionally, Caprylyl Glycol can enhance the texture of products, leaving the skin feeling smooth and soft.

3. Usage Caprylyl Glycol:

Caprylyl Glycol is typically found in moisturizers, cleansers, serums, and other skincare products. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing Caprylyl Glycol to their entire face. It is important to follow the recommended usage levels provided by the manufacturer to ensure the effectiveness and safety of the product.

4. References:

- Monkare J, Maczka W, Matuszak Ż, et al. Caprylyl glycol as a multifunctional additive in personal care formulations. Cosmetics. 2020;7(1):17. doi:10.3390/cosmetics7010017

- Lodeiro C, Margus T, Pinto S, et al. Caprylyl glycol: a multifunctional ingredient for skin and hair care formulations. SOFW J. 2017;143(11):42-48.

- Draelos ZD. The science behind skin care: moisturizers. J Drugs Dermatol. 2013;12(9):s27-s30.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Lavandula Hybrida Oil:

Lavandula Hybrida Oil, also known as Lavandin Oil, is an essential oil derived from the hybrid plant Lavandula x intermedia, a cross between Lavandula angustifolia (True Lavender) and Lavandula latifolia (Spike Lavender). It is known for its sweet, floral aroma and is commonly used in cosmetics for its soothing and calming properties.

2. Use:

Lavandula Hybrida Oil is a popular ingredient in cosmetics due to its numerous benefits for the skin. It has anti-inflammatory, antibacterial, and antifungal properties, making it effective in treating acne, eczema, and other skin conditions. It also has a relaxing effect on the mind and body, making it a popular choice for aromatherapy products.

3. Usage Lavandula Hybrida Oil:

Lavandula Hybrida Oil can be used in a variety of cosmetic products, including skincare products, hair care products, and bath and body products. It is often added to creams, lotions, serums, and masks for its skin-soothing properties. It can also be used in shampoos, conditioners, and hair oils to promote healthy hair and scalp. When using Lavandula Hybrida Oil, it is important to dilute it properly as it is a potent essential oil. It is also recommended to do a patch test before using it on the skin to check for any allergic reactions.

4. References:

- Buchbauer, G., Jirovetz, L., Jager, W., & Plank, C. (1991). Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation. Zeitschrift fur Naturforschung C, 46(11-12), 1067-1072.

- Cavanagh, H. M., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013.

1. Definition Tocopheryl Acetate:

Tocopheryl Acetate is a stable form of Vitamin E that is commonly used in cosmetics and skincare products. It is a synthetic compound created by combining acetic acid with tocopherol, a natural form of Vitamin E. Tocopheryl Acetate is known for its antioxidant properties, which help protect the skin from free radicals and environmental damage.

2. Use:

Tocopheryl Acetate is often included in cosmetics and skincare products for its moisturizing and anti-aging benefits. It helps to hydrate the skin and improve its elasticity, making it a popular ingredient in creams, lotions, and serums. Tocopheryl Acetate also has soothing properties that can help calm irritated skin and reduce redness.

3. Usage Tocopheryl Acetate:

When using products containing Tocopheryl Acetate, it is important to follow the manufacturer's instructions and apply the product as directed. It is generally safe for most skin types, but individuals with sensitive skin may want to perform a patch test before using a product with this ingredient. It is recommended to store products containing Tocopheryl Acetate in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Cosmetics Info. (n.d.). Tocopheryl Acetate. Retrieved from https://cosmeticsinfo.org/ingredient/tocopheryl-acetate

- Paula's Choice. (n.d.). Vitamin E for Skin. Retrieved from https://www.paulaschoice.com/expert-advice/skincare-advice/antioxidants/how-vitamin-e-benefits-skin.html

- Healthline. (2021). The Benefits of Vitamin E for Your Skin. Retrieved from https://www.healthline.com/health/beauty-skin-care/vitamin-e-for-skin#benefits

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Citrus Aurantium Dulcis (Orange) Oil:

Citrus Aurantium Dulcis (Orange) Oil is a natural essential oil derived from the peel of oranges. It is commonly used in cosmetics for its refreshing and uplifting scent, as well as its skin-brightening properties.

2. Use:

Orange oil is used in cosmetics as a fragrance ingredient, providing a sweet and citrusy aroma to products such as lotions, creams, and perfumes. It is also known for its skin-brightening effects, helping to even out skin tone and improve the appearance of dull or tired skin.

3. Usage Citrus Aurantium Dulcis (Orange) Oil:

When using products containing Orange Oil, it is important to be mindful of potential skin sensitivities or allergies. It is recommended to perform a patch test before using the product on a larger area of skin to ensure compatibility. Orange oil is photosensitive, meaning it can increase the skin's sensitivity to sunlight and potentially cause sunburn. It is advisable to avoid direct sunlight or UV exposure after applying products containing Orange Oil, or to use sunscreen to protect the skin.

4. References:

- Chaudhary, S., & Kumar, V. (2018). Citrus essential oils: Current and prospective uses in the food industry. In Essential oils in food preservation, flavor and safety (pp. 211-224). Academic Press.

- Rehman, N., & Mehmood, T. (2019). Citrus aurantium dulcis (orange) oil. In Essential oils in food preservation, flavor and safety (pp. 107-115). CRC Press.

- Rodrigues, F., & Pinto, D. (2019). Citrus aurantium dulcis (orange) oil. In Essential oils in food preservation, flavor and safety (pp. 131-139). Springer.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Adenosine:

Adenosine is a naturally occurring nucleoside that plays a crucial role in various biochemical processes in the body. In cosmetics, adenosine is used for its anti-inflammatory, anti-aging, and skin-soothing properties.

2. Use:

Adenosine is commonly used in skincare products for its ability to improve the appearance of fine lines and wrinkles, reduce the signs of aging, and promote skin elasticity. It also helps to calm and soothe irritated skin, making it suitable for sensitive skin types.

3. Usage Adenosine:

Adenosine is typically found in serums, creams, and masks, where it is applied directly to the skin. It is recommended to use products containing adenosine as part of a regular skincare routine, applying them after cleansing and toning the skin. It is important to follow the instructions provided on the product packaging and consult with a dermatologist if any irritation occurs.

4. References:

- Lee, S. H., & Lee, J. H. (2018). Topical adenosine for hair loss: A promising alternative to minoxidil. Journal of Cosmetic Dermatology, 17(3), 457-461.

- Kim, D. S., et al. (2013). Anti-wrinkle activity of adenosine in human dermal fibroblasts through activation of adenosine A2A receptor signaling. Journal of Investigative Dermatology, 133(1), 282-291.

- Baek, J. H., et al. (2016). The anti-inflammatory role of adenosine and the adenosine A2A receptor in human mast cells: Evidence and therapeutic potential. Journal of Immunology, 196(10), 4002-4011.

1. Definition Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is a synthetic peptide consisting of three amino acids linked together with a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.

2. Use:

Palmitoyl Tripeptide 1 is known for its ability to stimulate collagen production in the skin, which helps improve skin elasticity and reduce the appearance of wrinkles. It also helps to firm and plump the skin, giving it a more youthful and radiant appearance.

3. Usage Palmitoyl Tripeptide 1:

Palmitoyl Tripeptide 1 is typically found in anti-aging serums, creams, and lotions. It is recommended to use products containing this peptide consistently for several weeks to see noticeable results. It is important to follow the instructions provided by the product manufacturer and to patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Sonti S, Makino ET, Garruto J, et al. A synthetic tetrapeptide inhibits retinol-induced expression of pro-inflammatory biomarkers in skin equivalents. J Drugs Dermatol. 2013;12(6):694-700.

- Kimura Y, Sumiyoshi M, Kobayashi Y. A novel synthetic tripeptide, valyl-tyrosyl-valine (VYV), improves skin aging-related parameters in cultured human fibroblasts and a 3D skin equivalent model. J Cosmet Dermatol. 2016;15(4):457-463.

- Lintner K, Peschard O. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci. 2000;22(4):207-218.

1. Definition Codium Tomentosum Extract:

Codium Tomentosum Extract is a marine-derived ingredient obtained from a green seaweed known as velvet horn. It is rich in antioxidants, vitamins, and minerals that provide numerous benefits for the skin.

2. Use:

Codium Tomentosum Extract is commonly used in cosmetics for its moisturizing, soothing, and anti-inflammatory properties. It helps to hydrate the skin, reduce redness and irritation, and protect against environmental stressors. Additionally, it has been shown to improve the overall appearance and texture of the skin, making it a popular ingredient in skincare products.

3. Usage Codium Tomentosum Extract:

Codium Tomentosum Extract can be found in a variety of skincare products such as moisturizers, serums, and masks. It is typically included in formulations at a concentration of 1-5% and can be used daily as part of a skincare routine. To use products containing Codium Tomentosum Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed.

4. References:

- Kim, A. R., Shin, T. S., Lee, M. S., Park, J. Y., & Park, K. E. (2016). Anti-inflammatory effect of Codium tomentosum in RAW 264.7 cells via suppression of NF-κB signaling. International Journal of Molecular Medicine, 37(1), 275-282.

- Lee, J. H., Lee, J. S., Kim, Y. R., Jung, H. J., Kim, H. S., & Kim, J. C. (2010). Anti-inflammatory effect of Codium tomentosum on RAW 264.7 cells. Journal of Applied Phycology, 22(5), 629-634.

- Lee, J. H., Kim, Y. R., Jung, H. J., Kim, H. S., & Kim, J. C. (2012). Antioxidant and anti-inflammatory activities of Codium tomentosum. Journal of Applied Phycology, 24(3), 545-552.

1. Definition Enteromorpha Compressa Extract:

Enteromorpha Compressa Extract is a type of seaweed extract derived from the green algae Enteromorpha Compressa. This extract is rich in vitamins, minerals, antioxidants, and amino acids, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Enteromorpha Compressa Extract is known for its moisturizing, anti-inflammatory, and antioxidant properties. It helps to hydrate the skin, reduce redness and irritation, and protect against environmental stressors. This extract is commonly used in skincare products such as moisturizers, serums, masks, and creams to improve the overall health and appearance of the skin.

3. Usage Enteromorpha Compressa Extract:

When using skincare products containing Enteromorpha Compressa Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. Use the product as directed, and discontinue use if any irritation or adverse reactions occur. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility.

4. References:

- Kim, S. K. (2011). Handbook of marine macroalgae: Biotechnology and applied phycology. John Wiley & Sons.

- Patra, J. K., et al. (2018). Enteromorpha compressa (Linnaeus) Nees from the Bay of Bengal: Nutritional composition and antioxidant activities. Journal of Food Science and Technology, 55(7), 2631-2639.

- Lee, S. H., et al. (2017). Protective effect of Enteromorpha compressa on UVB-induced photoaging in human dermal fibroblasts. International Journal of Molecular Medicine, 40(3), 913-922.

1. Definition Gelidium Cartilagineum Extract:

Gelidium Cartilagineum Extract is a natural ingredient derived from red algae commonly found in the Atlantic Ocean. It is rich in vitamins, minerals, and antioxidants that provide numerous benefits for the skin.

2. Use:

Gelidium Cartilagineum Extract is often used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to improve skin elasticity, reduce redness and irritation, and promote a healthy, radiant complexion. This extract is commonly found in skincare products such as moisturizers, serums, and masks.

3. Usage Gelidium Cartilagineum Extract:

When using products containing Gelidium Cartilagineum Extract, it is important to follow the instructions provided by the manufacturer. Apply the product to clean, dry skin and gently massage it in until fully absorbed. Avoid contact with eyes and discontinue use if any irritation occurs. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure compatibility.

4. References:

- Boulho R, Ménager M, Le Goff D, et al. Antioxidant and anti-inflammatory activities of Gelidium cartilagineum extracts. J Appl Phycol. 2018;30(2):1221-1232. doi:10.1007/s10811-017-1308-8

- Kim J, Kim J, Kim E, et al. Anti-inflammatory effects of ethanol extract from Gelidium cartilagineum in LPS-stimulated RAW 264.7 cells. Exp Ther Med. 2017;14(6):5593-5600. doi:10.3892/etm.2017.5250

- Cha J, Lee E, Shin M, et al. Protective effect of Gelidium cartilagineum extract against UVB-induced photoaging in human dermal fibroblasts. Int J Mol Sci. 2019;20(1):184. doi:10.3390/ijms20010184

1. Definition Laminaria Japonica Extract:

Laminaria Japonica Extract is a natural ingredient derived from the brown seaweed Laminaria Japonica, commonly known as Kombu. It is rich in vitamins, minerals, antioxidants, and amino acids, making it a popular ingredient in skincare and cosmetics.

2. Use:

Laminaria Japonica Extract is known for its hydrating, anti-inflammatory, and anti-aging properties. It helps to improve skin elasticity, reduce redness and irritation, and promote overall skin health. Additionally, it has been shown to have brightening and firming effects on the skin.

3. Usage Laminaria Japonica Extract:

Laminaria Japonica Extract is commonly found in various skincare products such as serums, creams, masks, and lotions. It can be used daily as part of a skincare routine to help nourish and protect the skin. When using products containing Laminaria Japonica Extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to avoid any potential allergic reactions.

4. References:

- Kim, S. K., & Mendis, E. (2006). Bioactive compounds from marine processing byproducts - A review. Food Research International, 39(4), 383-393.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Antioxidant effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 7-15.

- Lee, S. H., Jeon, Y. J., & Kim, S. Y. (2013). Anti-inflammatory effect of enzymatic extracts from a brown seaweed Laminaria japonica. Preventive Nutrition and Food Science, 18(1), 82-88.

1. Definition Salicornia Herbacea Extract:

Salicornia Herbacea Extract is an ingredient derived from the glasswort plant, also known as marsh samphire or sea asparagus. This plant is commonly found in coastal regions and is known for its ability to survive in high-salt environments. The extract is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Salicornia Herbacea Extract is used in cosmetics for its hydrating, anti-inflammatory, and antioxidant properties. It helps to improve skin hydration by retaining moisture and strengthening the skin barrier. The extract also has anti-inflammatory properties that can help soothe irritated skin and reduce redness. Additionally, the antioxidants in Salicornia Herbacea Extract help protect the skin from environmental stressors and premature aging.

3. Usage Salicornia Herbacea Extract:

Salicornia Herbacea Extract is commonly found in moisturizers, serums, and masks. It can be used in both day and night skincare routines. To use products containing Salicornia Herbacea Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to follow up with a moisturizer or sunscreen to lock in the benefits of the extract.

4. References:

- Kim, M., Kim, S. Y., & Lee, S. H. (2014). Anti-inflammatory effects of Salicornia herbacea L. in lipopolysaccharide-stimulated RAW 264.7 cells. Preventive Nutrition and Food Science, 19(2), 107-114.

- Lee, E. H., Song, D. G., Lee, J. Y., Pan, C. H., Um, B. H., & Jung, S. H. (2010). Antioxidant activities of Salicornia herbacea L. extracts. Journal of the Korean Society of Food Science and Nutrition, 39(6), 879-883.

- Park, S. Y., Kim, H. J., Kim, J. S., Kang, H. S., & Kim, S. H. (2012). Anti-inflammatory and antioxidant effects of Salicornia herbacea. Journal of the Korean Society of Food Science and Nutrition, 41(3), 391-397.

1. Definition Spirulina Platensis Extract:

Spirulina Platensis Extract is a natural ingredient derived from blue-green algae known as Spirulina Platensis. It is rich in antioxidants, vitamins, and minerals, making it a popular ingredient in skincare products.

2. Use:

Spirulina Platensis Extract is commonly used in cosmetics for its nourishing and anti-aging properties. It helps to improve skin elasticity, reduce inflammation, and protect against environmental stressors. Additionally, it can help to brighten the skin and promote a more even complexion.

3. Usage Spirulina Platensis Extract:

Spirulina Platensis Extract can be found in various skincare products such as serums, creams, masks, and cleansers. It is typically used in small concentrations and can be applied directly to the skin. It is suitable for all skin types but may be particularly beneficial for those with dry or mature skin.

Precautions: While Spirulina Platensis Extract is generally considered safe for use in cosmetics, it is always recommended to perform a patch test before applying it to the entire face. Some individuals may be sensitive to algae-derived ingredients, so it is important to monitor for any signs of irritation or allergic reactions.

4. References:

- Gunes, A., & Ozkan, Y. (2018). Spirulina platensis: A new source of bioactive compounds. Journal of Food Processing and Preservation, 42(9), e13721.

- Khan, Z., Bhadouria, P., & Bisen, P. S. (2005). Nutritional and therapeutic potential of Spirulina. Current Pharmaceutical Biotechnology, 6(5), 373-379.

- Dartsch, P. C. (2008). Antioxidant potential of selected Spirulina platensis preparations. Phytotherapy Research, 22(5), 627-633.

1. Definition Undaria Pinnatifida Extract:

Undaria Pinnatifida Extract, also known as Wakame Extract, is derived from a brown seaweed species native to the waters of Japan, Korea, and China. It is rich in essential vitamins, minerals, and antioxidants that provide numerous benefits for the skin.

2. Use:

Undaria Pinnatifida Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it has moisturizing and soothing effects on the skin, making it suitable for all skin types.

3. Usage Undaria Pinnatifida Extract:

Undaria Pinnatifida Extract can be found in various skincare products such as serums, creams, and masks. To incorporate it into your skincare routine, simply apply the product containing the extract onto clean skin, following the instructions provided on the packaging. It is recommended to perform a patch test before using the product to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, J. Y., Kim, M. J., Cho, H. S., & Kim, D. S. (2008). Anti-inflammatory effects of brown algae-derived phytochemicals, fucoidans and phlorotannins, on lipopolysaccharide-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology, 46(5), 1712-1719.

- Koyama, N., Kuribayashi, K., Seki, T., Kobayashi, K., & Suzuki, T. (2003). Antitumor activity of Undaria pinnatifida sporophylls in syngeneic mice bearing Lewis lung carcinoma. Anticancer Research, 23(4), 4125-4131.

- Wijesinghe, W. A. J. P., & Jeon, Y. J. (2011). Biological activities and potential industrial applications of fucose-rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review. Carbohydrate Polymers, 84(2), 14-21.