Up&Up Benzoyl Peroxide Gel 10%

1. Definition Benzoyl Peroxide:

Benzoyl Peroxide is a topical medication commonly used in skincare products to treat acne. It works by reducing the amount of acne-causing bacteria on the skin and helping to unclog pores.

2. Use:

Benzoyl Peroxide is primarily used in over-the-counter and prescription acne treatments, such as creams, gels, and washes. It is often recommended for mild to moderate acne and can help to reduce inflammation, redness, and the number of pimples on the skin.

3. Usage Benzoyl Peroxide:

When using products containing Benzoyl Peroxide, it is important to follow the instructions provided by the manufacturer or healthcare provider. Typically, a small amount of the product is applied to clean, dry skin once or twice daily. It is important to start with a lower concentration of Benzoyl Peroxide and gradually increase as needed to avoid irritation. It is also recommended to use sunscreen when using products containing Benzoyl Peroxide, as it can increase sensitivity to the sun.

4. References:

- Draelos, Z. D. (2016). Over-the-counter acne treatments. Dermatologic clinics, 34(2), 175-184.

- Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., ... & Bhushan, R. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.

- Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A., Araviiskaia, E., Barona Cabal, M. I., ... & Layton, A. M. (2019). Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne. Journal of the American Academy of Dermatology, 81(3), 775-789.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Hydroxypropyl Methylcellulose:

Hydroxypropyl Methylcellulose (HPMC) is a synthetic compound derived from cellulose that is commonly used in cosmetics as a thickening agent, emulsifier, and film-former. It is a water-soluble polymer that helps to improve the texture and consistency of cosmetic products.

2. Use:

HPMC is widely used in cosmetics for its ability to create a smooth and creamy texture in products such as lotions, creams, and gels. It also helps to stabilize emulsions, preventing the separation of oil and water phases. Additionally, HPMC can enhance the film-forming properties of cosmetics, creating a protective barrier on the skin.

3. Usage Hydroxypropyl Methylcellulose:

When using products containing HPMC, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products with HPMC to their entire face or body. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Kim, S., et al. (2017). Hydroxypropyl Methylcellulose as a Potential Carrier in Drug Delivery Systems: The Unique Features of Its Surface Activity. Journal of Pharmaceutical Sciences, 106(6), 1956-1963.

- Lopes, M., et al. (2019). Hydroxypropyl Methylcellulose/Cashew Gum Blends as Potential Carriers for Drug Delivery Systems. Carbohydrate Polymers, 216, 1-9.

- Ribeiro, L., et al. (2020). Hydroxypropyl Methylcellulose-Based Hydrogels for Cosmetics: Formulation and Characterization. International Journal of Cosmetic Science, 42(1), 89-98.