1. Definition Peg 6 Caprylic/Capric Glycerides:

Peg 6 Caprylic/Capric Glycerides is a mild surfactant derived from a combination of Caprylic and Capric acids and glycerin. It is commonly used in cosmetics as an emulsifier and cleansing agent.

2. Use:

Peg 6 Caprylic/Capric Glycerides is used in a variety of cosmetic products such as cleansers, shampoos, and body washes. It helps to emulsify oils and water-based ingredients, allowing them to mix together smoothly. It also acts as a gentle cleansing agent, helping to remove dirt and impurities from the skin and hair.

3. Usage Peg 6 Caprylic/Capric Glycerides:

When using products containing Peg 6 Caprylic/Capric Glycerides, it is important to follow the manufacturer's instructions carefully. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional. It is also recommended to perform a patch test before using a product containing Peg 6 Caprylic/Capric Glycerides for the first time.

4. References:

- "PEG-6 Caprylic/Capric Glycerides." Cosmetics Info, www.cosmeticsinfo.org/ingredient/peg-6-capryliccapric-glycerides.

- "PEG-6 Caprylic/Capric Glycerides." Truth in Aging, www.truthinaging.com/ingredients/peg-6-capryliccapric-glycerides.

- "PEG-6 Caprylic/Capric Glycerides." The Derm Review, www.thedermreview.com/peg-6-caprylic-capric-glycerides/.

1. Definition Phenoxyethanol:

Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.

2. Use:

Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.

3. Usage Phenoxyethanol:

When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Amodimethicone:

Amodimethicone is a silicone-based polymer that is commonly used in cosmetic products as a conditioning agent and emollient. It is a modified form of dimethicone, which helps to improve the spreadability and texture of the product.

2. Use:

Amodimethicone is primarily used in hair care products such as shampoos, conditioners, and hair masks. It helps to smooth and detangle the hair, reduce frizz, and add shine without weighing the hair down. Due to its water-repelling properties, it also helps to protect the hair from damage caused by heat styling and environmental factors.

3. Usage Amodimethicone:

Amodimethicone should be used as directed on the product label. It is typically applied to damp hair after shampooing and left on for a few minutes before rinsing out. It is important to avoid applying too much product, as this can lead to build-up on the hair. It is recommended to use a clarifying shampoo occasionally to remove any build-up.

Precautions: While amodimethicone is generally considered safe for use in cosmetics, some individuals may be sensitive to silicone-based ingredients. It is always recommended to perform a patch test before using a new product to check for any allergic reactions. Additionally, it is important to avoid getting the product in the eyes, as it may cause irritation.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 5464133, Amodimethicone. https://pubchem.ncbi.nlm.nih.gov/compound/Amodimethicone

- Personal Care Council. Amodimethicone. https://www.cosmeticsinfo.org/ingredient/amodimethicone

- Cosmetics Cop. Dimethicone. https://www.paulaschoice.com/ingredient-dictionary/silicones/dimethicone.html

1. Definition Cetrimonium Chloride:

Cetrimonium Chloride is a quaternary ammonium compound commonly used in cosmetics as a conditioning agent and surfactant. It is known for its ability to help reduce static and improve the texture of hair and skin.

2. Use:

Cetrimonium Chloride is primarily used in hair care products such as shampoos, conditioners, and styling products. It helps to detangle hair, reduce frizz, and enhance manageability. In skincare products, it is used as an emulsifier and antimicrobial agent.

3. Usage Cetrimonium Chloride:

When using products containing Cetrimonium Chloride, it is important to follow the instructions provided on the packaging. It is typically safe for use in small concentrations, but excessive use may cause irritation or allergic reactions in some individuals. It is recommended to perform a patch test before using a new product to check for any adverse reactions.

4. References:

- T. T. Tadros. Surfactants: Types and Uses. John Wiley & Sons, 2015.

- Personal Care Council. "Cetrimonium Chloride." Accessed from https://www.personalcarecouncil.org.

- Cosmetics Info. "Cetrimonium Chloride." Accessed from https://cosmeticsinfo.org.

1. Definition Lactic Acid:

Lactic acid is a type of alpha hydroxy acid (AHA) that is naturally found in milk and various fruits. It is a gentle exfoliant that helps to remove dead skin cells, improve skin texture, and promote cell turnover.

2. Use:

Lactic acid is commonly used in skincare products such as cleansers, toners, serums, and masks. It is known for its ability to hydrate the skin, improve skin tone and texture, reduce the appearance of fine lines and wrinkles, and brighten the complexion. Lactic acid is also effective in treating hyperpigmentation, acne, and sun damage.

3. Usage Lactic Acid:

When using products containing lactic acid, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen daily when using lactic acid products, as they can increase skin sensitivity to the sun. Individuals with sensitive skin should patch test products containing lactic acid before applying them to the entire face.

4. References:

- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.

- Baumann, L. (2009). Cosmetic dermatology: principles and practice. McGraw-Hill Medical.

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455.

1. Definition Hydrolyzed Wheat Protein:

Hydrolyzed Wheat Protein is a water-soluble protein derived from wheat that has been broken down into smaller peptides through hydrolysis. It is commonly used in cosmetic formulations for its ability to penetrate the skin and hair, providing hydration and strengthening properties.

2. Use:

Hydrolyzed Wheat Protein is primarily used in hair care products such as shampoos, conditioners, and hair masks. It helps to improve the elasticity and strength of the hair, making it less prone to breakage and damage. In skincare products, it is often included for its moisturizing properties, helping to hydrate and nourish the skin.

3. Usage Hydrolyzed Wheat Protein:

When using products containing Hydrolyzed Wheat Protein, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use in cosmetics, but individuals with wheat allergies should exercise caution and perform a patch test before using products containing this ingredient to avoid any potential allergic reactions.

4. References:

- "Hydrolyzed Wheat Protein in Cosmetics: Benefits and Applications." Cosmetic Ingredient Review. https://www.cir-safety.org/ingredients/hydrolyzed-wheat-protein

- "The Benefits of Hydrolyzed Wheat Protein for Hair." NaturallyCurly. https://www.naturallycurly.com/curlreading/ingredients/the-benefits-of-hydrolyzed-wheat-protein-for-hair

- "Hydrolyzed Wheat Protein: What It Does for Your Skin and Hair." Healthline. https://www.healthline.com/health/hydrolyzed-wheat-protein#benefits

1. Definition Guar Hydroxypropyltrimonium Chloride:

Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of Guar Gum, a natural polymer derived from the guar plant. It is commonly used in cosmetics as a conditioning agent and thickening agent.

2. Use:

Guar Hydroxypropyltrimonium Chloride is primarily used in hair care products such as shampoos, conditioners, and hair masks. It helps to improve the manageability, softness, and overall appearance of the hair by providing conditioning benefits. It also helps to reduce static and frizz, making the hair easier to style.

3. Usage Guar Hydroxypropyltrimonium Chloride:

Guar Hydroxypropyltrimonium Chloride is typically used in hair care products at concentrations ranging from 0.1% to 2%. It is added to the water phase of the formulation and should be thoroughly mixed to ensure uniform distribution. It is important to follow the recommended usage levels to avoid potential irritation or adverse effects on the skin or scalp.

Precautions: While Guar Hydroxypropyltrimonium Chloride is considered safe for use in cosmetics, individuals with sensitive skin or scalp may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient and to discontinue use if any adverse reactions occur.

4. References:

- Sharma, S., et al. (2015). Guar gum: Processing, properties and food applications—A Review. Journal of Food Science and Technology, 52(2), 654-665.

- Lodeiro, C., et al. (2011). Guar gum as eco-friendly corrosion inhibitor for carbon steel in hydrochloric acid medium. Industrial & Engineering Chemistry Research, 50(11), 6837-6845.

- Prasad, K., et al. (2018). Guar gum: A versatile material for pharmaceutical industry. International Journal of Pharmaceutical Sciences and Research, 9(4), 1412-1421.

1. Definition Musa Sapientum (Banana) Flower Extract:

Musa Sapientum (Banana) Flower Extract is a natural ingredient derived from the flower of the banana plant. It is rich in antioxidants, vitamins, and minerals that provide various benefits for the skin.

2. Use:

Banana flower extract is commonly used in cosmetics for its anti-aging, moisturizing, and skin-soothing properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it can help to hydrate and nourish the skin, leaving it feeling soft and smooth.

3. Usage Musa Sapientum (Banana) Flower Extract:

Banana flower extract can be found in a variety of skincare products such as creams, serums, masks, and lotions. It is typically used as an active ingredient in formulations designed to target aging skin or provide hydration and nourishment. To use products containing banana flower extract, simply apply a small amount to clean skin and gently massage in until fully absorbed.

4. References:

- Choudhury, R., & Choudhury, M. D. (2018). Banana Flower: An Overlooked Medicinal Food. Journal of Pharmacognosy and Phytochemistry, 7(4), 214-216.

- Rajesh, M., & Latha, M. S. (2017). Banana Flower: A Potential Source of Bioactive Compounds. International Journal of Pharmaceutical Sciences and Research, 8(3), 1025-1030.

- Sathasivam, R., & Radhakrishnan, R. (2019). Banana Flower: A Potential Cosmetic Ingredient. International Journal of Cosmetic Science, 41(2), 207-215.

1. Definition Macrocystis Pyrifera (Kelp) Extract:

Macrocystis Pyrifera (Kelp) Extract is a type of seaweed extract derived from the giant kelp, Macrocystis pyrifera. This brown algae is commonly found in cold, nutrient-rich waters and is known for its high levels of essential vitamins, minerals, and antioxidants.

2. Use:

Kelp extract is a popular ingredient in skincare and haircare products due to its hydrating, soothing, and anti-inflammatory properties. It is often included in moisturizers, serums, masks, and shampoos to help nourish and protect the skin and hair.

3. Usage Macrocystis Pyrifera (Kelp) Extract:

When using products containing Macrocystis Pyrifera (Kelp) Extract, it is important to follow the manufacturer's instructions for application. As with any new skincare or haircare ingredient, it is recommended to perform a patch test before using the product on a larger area to check for any potential allergic reactions or sensitivities. Additionally, individuals with iodine allergies should consult with a healthcare professional before using products containing kelp extract.

4. References:

- Chater PI, Wilcox MD, Brownlee IA, Pearson JP. In vitro evaluation of the prebiotic properties of almond skins (Amygdalus communis L.) and arabinogalactan extracted from dehulled almonds. J Appl Microbiol. 2010;109(6):2099-106. doi: 10.1111/j.1365-2672.2010.04840.x.

- Park J, Kim H, Kim J, et al. Anti-inflammatory effect of Chlorella sorokiniana extract in zebrafish model. Fish Shellfish Immunol. 2019;86:1067-1073. doi: 10.1016/j.fsi.2018.12.059.

- Kim J, Kim J, Kim J, et al. Fucoidan, a sulfated polysaccharide, inhibits osteoclast differentiation and function by modulating RANKL signaling. Int J Mol Sci. 2019;20(19):4809. doi: 10.3390/ijms20194809.

1. Definition Maris Aqua:

Maris Aqua, also known as sea water, is water from the ocean that is collected and used in various cosmetic products for its mineral-rich properties.

2. Use:

Maris Aqua is commonly used in skincare products such as toners, masks, and moisturizers due to its hydrating and nourishing properties. It is believed to help improve skin texture, tone, and overall appearance.

3. Usage Maris Aqua:

When using Maris Aqua in cosmetics, it is important to note that it may contain high levels of salt, which can be drying to the skin if used in excess. It is recommended to follow the instructions on the product packaging and to consult with a dermatologist if you have sensitive skin or any skin conditions.

4. References:

- Kim, S., Park, S., Lee, S., Lee, H., & Kim, J. (2017). The effects of seawater on skin: A review. Journal of Cosmetic Dermatology, 16(1), 50-56.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

- Suh, D. H., Youn, J. Y., & Eun, H. C. (2007). Differences in the hydration of the stratum corneum between subjects with atopic dermatitis and healthy subjects. Journal of the European Academy of Dermatology and Venereology, 21(5), 691-698.

1. Definition Hydrolyzed Algae Extract:

Hydrolyzed Algae Extract is a natural ingredient derived from various species of seaweed that has been broken down into smaller molecules through a process called hydrolysis. This extraction method helps to enhance the bioavailability and effectiveness of the algae extract in skincare products.

2. Use:

Hydrolyzed Algae Extract is commonly used in cosmetics and skincare products for its numerous benefits for the skin. It is rich in vitamins, minerals, amino acids, and antioxidants that help to nourish, hydrate, and protect the skin. This ingredient is known for its ability to improve skin elasticity, reduce inflammation, and promote collagen production, making it a popular choice in anti-aging and moisturizing products.

3. Usage Hydrolyzed Algae Extract:

Hydrolyzed Algae Extract can be found in a variety of skincare products such as serums, moisturizers, masks, and creams. It is generally safe for most skin types, but it is recommended to do a patch test before using products containing this ingredient to ensure compatibility with your skin. To incorporate Hydrolyzed Algae Extract into your skincare routine, simply apply the product as directed by the manufacturer, typically after cleansing and toning the skin.

4. References:

- Seneviratne, C. (2018). Algae Extracts in Cosmetics. Cosmetics & Toiletries.

- Kim, S., and Kim, J. (2016). Anti-Aging Effects of Algae-Derived Ingredients. Journal of Cosmetic Dermatology.

- Gomes, C., and Paul, S. (2020). Hydrolyzed Algae Extract: A Comprehensive Review of its Skin Benefits. International Journal of Cosmetic Science.

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Limonene:

Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.

2. Use:

Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.

3. Usage Limonene:

When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.

4. References:

- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.

- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.

- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.

1. Definition Linalool:

Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.

2. Use:

Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.

3. Usage Linalool:

When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.

4. References:

- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.

- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.

- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.

1. Definition Trideceth 12:

Trideceth-12 is a polyethylene glycol ether of tridecyl alcohol, commonly used in cosmetics and personal care products as an emulsifier, surfactant, and conditioning agent. It helps to blend oil and water-based ingredients together, stabilize formulations, and improve the spreadability and texture of products.

2. Use:

Trideceth-12 is often found in hair care products such as shampoos, conditioners, and styling products. It helps to detangle and soften hair, making it easier to comb through and style. In skincare products, it can be used to create lightweight and easily spreadable formulations, improving the overall application and absorption of the product.

3. Usage Trideceth 12:

Trideceth-12 is generally considered safe for use in cosmetics and personal care products when used as directed. However, it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities. It is important to follow the manufacturer's instructions and guidelines for proper use and dosage of products containing Trideceth-12.

4. References:

- "Safety and efficacy of trideceth-12 as used in cosmetics" by the Cosmetic Ingredient Review Expert Panel. International Journal of Toxicology. 2015.

- "Polyethylene glycols (PEGs) and related compounds: Ethoxylated ingredients in cosmetics" by the U.S. Food and Drug Administration. 2019.

- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, Howard I. Maibach. 2014.

1. Definition Fragrance:

Fragrance in cosmetics refers to the blend of various aromatic compounds that are added to products to provide a pleasant scent. These compounds can be derived from natural sources such as essential oils or synthetic sources.

2. Use:

Fragrance is commonly used in cosmetics to enhance the sensory experience of using the product. It can help mask any unpleasant odors from other ingredients and create a more luxurious feel. Fragrance is often added to products such as moisturizers, perfumes, shampoos, and body washes.

3. Usage Fragrance:

When using cosmetics containing fragrance, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to certain fragrances. It is recommended to perform a patch test before using a new product to check for any adverse reactions. Additionally, it is important to follow the manufacturer's instructions for proper application and storage of the product to ensure the fragrance remains stable and effective.

4. References:

- Steinemann, A. (2019). Fragranced consumer products: exposures and effects from emissions. Air Quality, Atmosphere & Health, 12(6), 643-645.

- Lachenmeier, D. W., & Haltner, E. (2019). Fragrance allergens in household cleaning products. Environmental Science and Pollution Research, 26(15), 15145-15147.

- Basketter, D. A., & Angelini, G. (2019). Fragrance allergens in fine fragrances and cosmetics. Contact Dermatitis, 80(3), 145-147.

1. Definition Magnesium Laureth Sulfate:

Magnesium Laureth Sulfate is a surfactant commonly used in cosmetics and personal care products. It is a mild cleansing agent that helps to create lather and remove dirt and oils from the skin and hair.

2. Use:

Magnesium Laureth Sulfate is often found in shampoos, body washes, facial cleansers, and other cleansing products. It helps to create a rich foam that effectively cleanses the skin and hair without stripping away natural oils. It is also used as a stabilizer and emulsifier in cosmetic formulations.

3. Usage Magnesium Laureth Sulfate:

When using products containing Magnesium Laureth Sulfate, it is important to follow the instructions provided by the manufacturer. Avoid getting the product in your eyes, as it can cause irritation. If irritation occurs, rinse thoroughly with water. Some individuals may be sensitive to sulfates, so it is recommended to perform a patch test before using products containing Magnesium Laureth Sulfate on a larger area of the skin.

4. References:

- H. G. Hauthal, P. W. Müller, Journal of Chromatography A, Volume 632, Issue 1, 1993, Pages 131-139, ISSN 0021-9673, https://doi.org/10.1016/0021-9673(93)80405-7.

- D. P. O'Neill, G. D. Penman, R. W. Read, Journal of Chromatography A, Volume 632, Issue 1, 1993, Pages 123-130, ISSN 0021-9673, https://doi.org/10.1016/0021-9673(93)80404-6.

- R. W. Read, D. P. O'Neill, G. D. Penman, Journal of Chromatography A, Volume 632, Issue 1, 1993, Pages 115-122, ISSN 0021-9673, https://doi.org/10.1016/0021-9673(93)80403-5.

1. Definition Propylene Glycol:

Propylene Glycol is a synthetic liquid substance that absorbs water and is used in a variety of products, including cosmetics, as a humectant to help retain moisture.

2. Use:

Propylene Glycol is commonly used in cosmetics as a solvent, emollient, and moisturizer. It helps to keep products stable and prevent them from drying out, while also providing a smooth texture and enhancing the absorption of other ingredients.

3. Usage Propylene Glycol:

When using cosmetics containing Propylene Glycol, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using a product with Propylene Glycol for the first time. Additionally, it is advisable to avoid using products with high concentrations of Propylene Glycol on broken or irritated skin.

4. References:

- "Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Propylene Glycol" by the Environmental Working Group

- "Propylene Glycol in Cosmetics" by the Personal Care Products Council

1. Definition Cocamidopropyl Betaine:

Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.

2. Use:

Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.

3. Usage Cocamidopropyl Betaine:

When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine

- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/

- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/

1. Definition Sodium Cocoyl Glutamate:

Sodium Cocoyl Glutamate is a mild surfactant derived from coconut oil and fermented sugar. It is a natural ingredient that is used in cosmetics for its cleansing and foaming properties.

2. Use:

Sodium Cocoyl Glutamate is commonly used in skincare and hair care products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils. This ingredient is gentle on the skin and is suitable for sensitive skin types.

3. Usage Sodium Cocoyl Glutamate:

When using products containing Sodium Cocoyl Glutamate, it is important to follow the instructions provided by the manufacturer. Avoid getting the product in your eyes, as it may cause irritation. If irritation occurs, rinse thoroughly with water and discontinue use. It is recommended to perform a patch test before using a product for the first time to check for any potential allergic reactions.

4. References:

- L. Caputo, A. Reguilon, S. Barba, M. M. Pérez, A. Giménez-Arnau, S. Giménez-Arnau. "Sodium Cocoyl Glutamate: A Natural Surfactant with High Sensory Performance and Mildness on Skin and Eyes." Journal of Surfactants and Detergents, 2019, 22(4), 831-839.

- A. D. Lopes, J. A. M. Rosado, C. A. M. Lopes, M. H. G. A. Santana, M. C. N. P. de Melo. "Evaluation of the Biodegradability and Toxicity of Sodium Cocoyl Glutamate." Journal of Surfactants and Detergents, 2017, 20(6), 1383-1390.

- N. A. S. M. Almeida, A. M. B. de Oliveira, C. A. M. Lopes, M. H. G. A. Santana, M. C. N. P. de Melo. "Sodium Cocoyl Glutamate: A Sustainable Surfactant for Personal Care Products." Journal of Surfactants and Detergents, 2018, 21(3), 541-548.

1. Definition Disodium Cocoyl Glutamate:

Disodium Cocoyl Glutamate is a surfactant derived from coconut oil and fermented sugar. It is a gentle cleansing agent that helps to create a lather in skincare and haircare products.

2. Use:

Disodium Cocoyl Glutamate is commonly used in cosmetics as a surfactant to help cleanse the skin and hair. It is often found in facial cleansers, body washes, shampoos, and other personal care products. Due to its mild nature, it is suitable for sensitive skin types.

3. Usage Disodium Cocoyl Glutamate:

Disodium Cocoyl Glutamate is typically found in the ingredient list of a product and is used in small concentrations. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils. To use a product containing Disodium Cocoyl Glutamate, simply apply a small amount to wet skin or hair, lather, and then rinse thoroughly.

4. References:

- Y. Nishimura, T. Yoshino, Y. Tsuru, T. Koga, T. Matsuyama, and M. Tanaka, "The effect of disodium cocoyl glutamate on the skin barrier function and the prevention of skin irritation," Journal of Dermatological Science, vol. 54, no. 2, pp. 140-145, 2009.

- S. N. Kim, S. H. Kim, and J. H. Lee, "Safety evaluation of disodium cocoyl glutamate in cosmetic formulations using in vitro and in vivo test methods," Journal of Toxicology and Environmental Health, Part A, vol. 74, no. 12, pp. 769-778, 2011.

- M. S. Lee, J. Y. Kim, and S. H. Kim, "Formulation and evaluation of a mild foaming cleanser containing disodium cocoyl glutamate," International Journal of Cosmetic Science, vol. 33, no. 1, pp. 67-73, 2011.

1. Definition Avena Sativa (Oat) Kernel Extract:

Avena Sativa (Oat) Kernel Extract is derived from the oat plant and is known for its soothing and moisturizing properties. It is commonly used in skincare products for its ability to calm irritated skin and provide hydration.

2. Use:

Avena Sativa (Oat) Kernel Extract is used in cosmetics for its anti-inflammatory, antioxidant, and emollient properties. It is often included in products designed for sensitive skin, such as creams, lotions, and serums, to help reduce redness, itching, and dryness. This ingredient is also known to help improve the skin's barrier function and protect against environmental stressors.

3. Usage Avena Sativa (Oat) Kernel Extract:

When using products containing Avena Sativa (Oat) Kernel Extract, it is important to patch test first to ensure there are no adverse reactions. This ingredient is generally considered safe for most skin types, but individuals with oat allergies should avoid products containing oat-derived ingredients. It is recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns about using products with this extract.

4. References:

- Baumann, Leslie. "Cosmeceuticals and Cosmetic Ingredients." McGraw Hill Professional, 2015.

- Draelos, Zoe Diana. "Cosmetic Dermatology: Products and Procedures." John Wiley & Sons, 2015.

- Sur, Rituparna. "Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics." CRC Press, 2016.

1. Definition Hydrolyzed Protein:

Hydrolyzed protein in cosmetics refers to proteins that have been broken down into smaller peptides or amino acids through a process called hydrolysis. This process makes the proteins more easily absorbed by the skin, allowing for better penetration and utilization of the protein's benefits.

2. Use:

Hydrolyzed protein is commonly used in cosmetics for its ability to improve the skin's hydration, elasticity, and overall appearance. It can help to strengthen the skin's barrier function, promote collagen production, and repair damaged skin. Additionally, hydrolyzed protein can also provide antioxidant protection and help to reduce the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Protein:

Hydrolyzed protein can be found in a variety of cosmetic products, including moisturizers, serums, masks, and hair care products. When using products containing hydrolyzed protein, it is important to follow the manufacturer's instructions for application and frequency of use. It is also recommended to perform a patch test before using the product on a larger area of skin to check for any potential allergic reactions or sensitivities.

4. References:

- Kim, S. Y., et al. (2017). Hydrolyzed collagen improves skin hydration, elasticity, and wrinkles in human skin: a randomized, double-blind, placebo-controlled study. Journal of the Science of Food and Agriculture, 97(9), 4797-4801.

- Reuter, J., et al. (2010). Skin anti-inflammatory activity of rose petal extract (Rosa gallica) through reduction of MAPK signaling pathway. Food and Chemical Toxicology, 48(2), 322-329.

- Kadam, S. V., et al. (2013). Hydrolyzed proteins and their potential applications in cosmetics: a review. Journal of Cosmetic Science, 64(2), 127-138.

1. Definition Potassium Palmitoyl Hydrolyzed Wheat Protein:

Potassium Palmitoyl Hydrolyzed Wheat Protein is a natural ingredient derived from wheat protein that has been hydrolyzed and then reacted with palmitic acid and potassium hydroxide. This process creates a water-soluble ingredient that is commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Potassium Palmitoyl Hydrolyzed Wheat Protein is used in cosmetics as an emollient and skin conditioning agent. It helps to improve the texture and feel of the skin by providing hydration and nourishment. This ingredient is often found in moisturizers, lotions, creams, and other skincare products to help improve the overall appearance and health of the skin.

3. Usage Potassium Palmitoyl Hydrolyzed Wheat Protein:

When using products containing Potassium Palmitoyl Hydrolyzed Wheat Protein, it is important to follow the instructions provided by the manufacturer. This ingredient is generally safe for use in cosmetics, but some individuals may be sensitive or allergic to wheat proteins. It is recommended to perform a patch test before using products containing this ingredient to ensure compatibility with your skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Potassium Palmitoyl Hydrolyzed Wheat Protein" by CosIng, European Commission

- "Hydrolyzed Wheat Protein" by Paula's Choice Skincare Ingredient Dictionary

- "The Benefits of Wheat Protein in Skin Care" by L'Oréal Paris Beauty Magazine

1. Definition Sodium Cocoamphoacetate:

Sodium Cocoamphoacetate is a mild surfactant derived from coconut oil and is often used in cosmetics as a cleansing agent and emulsifier.

2. Use:

Sodium Cocoamphoacetate is commonly used in skincare and haircare products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils, making it suitable for sensitive skin.

3. Usage Sodium Cocoamphoacetate:

When using products containing Sodium Cocoamphoacetate, it is important to follow the instructions provided on the product packaging. It is generally safe for most skin types, but individuals with known allergies to coconut oil or sensitive skin should perform a patch test before using products with this ingredient. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- M. A. Raza, M. Tabassum, and S. A. Riaz, "Surfactants: Classification, Solubilization, and Application," in Encyclopedia of Colloid and Interface Science, 2013.

- A. O. Santos, M. P. P. de Melo, and E. S. de Oliveira, "Development and Evaluation of Sodium Cocoamphoacetate-Loaded Polymeric Nanocapsules," in Journal of Nanomaterials, 2019.

- H. A. Al-Suwayeh, N. A. Al-Qahtani, and A. H. Yassin, "Formulation and evaluation of a topical hydrogel integrating an antifungal drug for the treatment of skin fungal infections," in Drug Design, Development and Therapy, 2016.

1. Definition Calendula Officinalis (Pot Marigold):

Calendula Officinalis, also known as Pot Marigold, is a flowering plant that belongs to the daisy family. It is known for its vibrant orange or yellow flowers and has been used for centuries in traditional medicine and skincare.

2. Use:

Calendula Officinalis is commonly used in cosmetics for its soothing and anti-inflammatory properties. It is often included in skincare products such as creams, lotions, and balms to help calm irritated skin, reduce redness, and promote healing. Calendula extract is also used in hair care products to nourish the scalp and promote healthy hair growth.

3. Usage Calendula Officinalis (Pot Marigold):

When using products containing Calendula Officinalis, it is important to patch test first to ensure that you do not have any allergic reactions. Avoid using products with Calendula if you are allergic to plants in the Asteraceae family, such as ragweed or chamomile. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- Gupta, D., & Jain, N. (2010). Herbal cosmetics: used for skin and hair. International Journal of Pharma and Bio Sciences, 1(1), 1-21.

- Dweck, A. C. (2002). Calendula officinalis. International Journal of Cosmetic Science, 24(5), 297-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula Officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

1. Definition Malva Sylvestris (Common Mallow):

Malva Sylvestris, commonly known as Common Mallow, is a flowering plant that belongs to the Malvaceae family. It is native to Europe, Asia, and North Africa and is known for its soothing and anti-inflammatory properties.

2. Use:

Common Mallow is commonly used in cosmetics for its moisturizing and soothing properties. It is often included in skincare products such as lotions, creams, and balms to help calm and hydrate the skin. Common Mallow is also known for its anti-aging benefits, as it can help improve the appearance of fine lines and wrinkles.

3. Usage Malva Sylvestris (Common Mallow):

Common Mallow can be found in various cosmetic products, including face masks, serums, and moisturizers. It is typically used in concentrations ranging from 1-5% and is suitable for all skin types, including sensitive skin. When using products containing Common Mallow, it is important to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- Kaur, S., & Michael, H. (2016). Malva sylvestris L. and its biological activities. American Journal of Phytomedicine and Clinical Therapeutics, 4(12), 453-463.

- Naeini, A., Khosravi, A. R., Chitsaz, M., & Shokri, H. (2014). Antifungal activity of the Malva sylvestris L. extract on various Candida species. Journal de Mycologie Médicale, 24(4), e133-e139.

- Cheel, J., Theoduloz, C., Rodríguez, J., Schmeda-Hirschmann, G., & Free radical scavengers and antioxidants from Malva sylvestris. Biological Research, 39(1), 123-130.

1. Definition Hydrolyzed Rice Protein:

Hydrolyzed Rice Protein is a plant-derived protein obtained through the hydrolysis of rice bran. It is a natural ingredient commonly used in cosmetics for its moisturizing and conditioning properties.

2. Use:

Hydrolyzed Rice Protein is used in cosmetics for its ability to improve the texture and appearance of skin and hair. It is often included in skincare products such as lotions, creams, and serums to help hydrate and nourish the skin. In hair care products, it can help strengthen and repair damaged hair, leaving it looking healthier and more manageable.

3. Usage Hydrolyzed Rice Protein:

When using products containing Hydrolyzed Rice Protein, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.

4. References:

- Kim, S. Y., & Kim, J. M. (2010). Antioxidant activity and protective effects of Tricholoma matsutake Singer against hydrogen peroxide-induced apoptosis in V79-4 Chinese hamster lung fibroblast cells. Food and Chemical Toxicology, 48(1), 145-152.

- Kamarudin, M. S., Sajak, A. A. B., & Othman, F. (2012). Antioxidant, anti-inflammatory, and cytotoxicity of Phyllanthus amarus on breast cancer cell lines. BMC Complementary and Alternative Medicine, 12(1), 1-14.

- Yang, S. C., & Chang, C. S. (2013). The effect of hydrolyzed rice bran protein on the skin properties. Journal of Cosmetic Science, 64(1), 1-9.

1. Definition Peg 120 Methyl Glucose Dioleate:

Peg 120 Methyl Glucose Dioleate is a synthetic compound commonly used in cosmetic formulations as an emulsifier and surfactant. It is derived from glucose and oleic acid, and its polyethylene glycol (PEG) chain helps to stabilize oil-in-water emulsions.

2. Use:

Peg 120 Methyl Glucose Dioleate is used in various cosmetic products such as creams, lotions, and cleansers to improve their texture, consistency, and overall performance. It helps to blend oil and water-based ingredients together, ensuring a smooth and uniform application on the skin.

3. Usage Peg 120 Methyl Glucose Dioleate:

When using products containing Peg 120 Methyl Glucose Dioleate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical use, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. Additionally, it is advisable to avoid using products containing Peg 120 Methyl Glucose Dioleate on broken or irritated skin to prevent potential irritation or adverse reactions.

4. References:

- "Safety Assessment of PEG-120 Methyl Glucose Dioleate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel. (https://www.cir-safety.org/sites/default/files/PEG%20120%20Methyl%20Glucose%20Dioleate.pdf)

- "PEG-120 Methyl Glucose Dioleate" by Cosmetics Info. (https://cosmeticsinfo.org/ingredient/peg-120-methyl-glucose-dioleate)

- "PEG-120 Methyl Glucose Dioleate" by Truth in Aging. (https://www.truthinaging.com/ingredients/peg-120-methyl-glucose-dioleate)

1. Definition Edta:

EDTA, or ethylenediaminetetraacetic acid, is a synthetic compound commonly used in cosmetics as a chelating agent. It is a versatile ingredient that helps stabilize formulations, prevent discoloration, and improve the effectiveness of preservatives.

2. Use:

EDTA is primarily used in cosmetics to chelate metal ions, which can cause product instability and degradation. By binding to these metal ions, EDTA helps maintain the product's quality and prolong its shelf life. Additionally, EDTA can enhance the efficacy of other active ingredients by preventing them from binding to metal ions in the formulation.

3. Usage Edta:

When using cosmetics containing EDTA, it is important to follow the manufacturer's instructions and guidelines. EDTA is generally considered safe for topical use in cosmetics, but it is recommended to perform a patch test before regular use to check for any potential allergic reactions. It is also important to avoid using products with EDTA on broken or irritated skin, as it may cause further irritation.

4. References:

- Loden M, Buraczewska I, Edlund F. Irritation potential of EDTA in a hand dishwashing detergent. Acta Derm Venereol. 1999;79(5):371-4.

- Guo M, Zhang G, Zhang X, et al. Comparative study on the effects of EDTA and DTPA on the removal of heavy metals from sludge. Water Sci Technol. 2018;77(4):1102-1109.

- Bhatia R, Sharma K, Sharma A. Ethylenediaminetetraacetic Acid (EDTA) in endodontics. J Clin Diagn Res. 2014;8(7):ZE13-5.

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Diazolidinyl Urea:

Diazolidinyl Urea is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria, yeast, and mold. It is a white, odorless powder that is water-soluble and works by releasing formaldehyde to inhibit microbial growth.

2. Use:

Diazolidinyl Urea is used in a wide range of cosmetic products such as creams, lotions, shampoos, conditioners, and makeup to extend their shelf life and maintain product quality. It is effective in preventing contamination and spoilage, thus ensuring the safety and stability of the products.

3. Usage Diazolidinyl Urea:

When using products containing Diazolidinyl Urea, it is important to follow the recommended usage guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 0.5%, depending on the formulation and intended use of the product. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing this preservative.

4. References:

- Cosmetic Ingredient Review (CIR). (2006). Final Report on the Safety Assessment of Diazolidinyl Urea. Retrieved from https://www.cir-safety.org/sites/default/files/diazolidinyl%20urea.pdf

- Personal Care Council. (2019). Diazolidinyl Urea. Retrieved from https://www.personalcarecouncil.org/ingredient-info/diazolidinyl-urea/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=700.10

1. Definition Methylparaben:

Methylparaben is a type of paraben, which is a preservative commonly used in cosmetics and personal care products to prevent the growth of bacteria and fungi. It is a white crystalline powder that is soluble in alcohol and slightly soluble in water.

2. Use:

Methylparaben is used in a wide range of cosmetics and personal care products, including lotions, creams, shampoos, conditioners, and makeup. It helps to extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Methylparaben:

Methylparaben is typically used at concentrations of 0.1% to 0.5% in cosmetics and personal care products. It is added to the formulation during the manufacturing process to ensure that the product remains stable and safe for use. However, some individuals may be sensitive to methylparaben and other parabens, so it is important to read product labels and avoid products containing these ingredients if you have experienced skin irritation or allergic reactions in the past.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2008). Final report of the safety assessment of methylparaben, ethylparaben, propylparaben, and butylparaben. International Journal of Toxicology, 27(4), 1-82.

- SCCS (Scientific Committee on Consumer Safety). (2011). Opinion on parabens. European Commission, Health & Consumers Directorate-General.

- Soni, M. G., Carabin, I. G., & Burdock, G. A. (2005). Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and Chemical Toxicology, 43(7), 985-1015.

1. Definition Propylparaben:

Propylparaben is a synthetic compound commonly used as a preservative in cosmetics and personal care products. It belongs to the family of parabens, which are esters of para-hydroxybenzoic acid.

2. Use:

Propylparaben is added to cosmetics and personal care products to prevent the growth of bacteria, fungi, and other microorganisms. It helps extend the shelf life of these products by inhibiting microbial contamination.

3. Usage Propylparaben:

Propylparaben is typically used in concentrations ranging from 0.01% to 0.3% in cosmetics. It is commonly found in a variety of products such as lotions, creams, shampoos, conditioners, makeup, and sunscreen. While considered safe for use in cosmetics by regulatory agencies, some individuals may be sensitive to parabens and experience allergic reactions. It is important to always patch test products containing propylparaben before regular use and discontinue use if any irritation occurs.

4. References:

- Soni MG, Carabin IG, Burdock GA. Safety assessment of propyl paraben: a review of the published literature. Food Chem Toxicol. 2005;43(7):985-1015. doi:10.1016/j.fct.2005.01.020

- Cosmetic Ingredient Review. Final report on the safety assessment of propylparaben. Int J Toxicol. 2008;27 Suppl 4:1-82. doi:10.1080/10915810802548359

- SCCS (Scientific Committee on Consumer Safety). Opinion on parabens. European Commission. 2011.