1. Definition Citric Acid:

Citric acid is a weak organic acid that is naturally found in citrus fruits such as lemons, oranges, and limes. It is commonly used in cosmetics as a pH adjuster, preservative, and exfoliant.

2. Use:

Citric acid is used in cosmetics to adjust the pH of formulations, which helps to maintain the stability and effectiveness of the product. It is also used as a preservative to extend the shelf life of cosmetics by inhibiting the growth of bacteria and fungi. Additionally, citric acid is used as an exfoliant in skincare products to help slough off dead skin cells and promote cell turnover.

3. Usage Citric Acid:

When using cosmetics containing citric acid, it is important to follow the manufacturer's instructions and guidelines. Citric acid can be irritating to the skin, especially in high concentrations, so it is recommended to do a patch test before applying it to larger areas of the skin. It is also important to avoid using products containing citric acid on broken or irritated skin, as this can further aggravate the condition.

4. References:

- "Citric Acid in Cosmetics: Is It Safe?" by Healthline

- "The Role of Citric Acid in Cosmetics" by The Derm Review

- "Citric Acid: Benefits, Uses, and Side Effects" by Verywell Health

1. Definition Ethylhexylglycerin:

Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.

2. Use:

Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.

3. Usage Ethylhexylglycerin:

Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.

4. References:

- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.

- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.

- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133

1. Definition Sodium Benzoate:

Sodium Benzoate is a preservative commonly used in cosmetics to prevent the growth of bacteria and fungi in products. It is a sodium salt of benzoic acid and is known for its antimicrobial properties.

2. Use:

Sodium Benzoate is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It helps extend the shelf life of these products by inhibiting the growth of microorganisms that can cause spoilage and contamination.

3. Usage Sodium Benzoate:

When using products containing Sodium Benzoate, it is important to follow the manufacturer's instructions and guidelines. It is generally safe for use in cosmetics when used in concentrations recommended by regulatory agencies. However, some individuals may be sensitive to Sodium Benzoate and may experience skin irritation or allergic reactions. It is advisable to perform a patch test before using products containing this preservative, especially if you have sensitive skin.

4. References:

- "Sodium Benzoate in Cosmetics: Uses and Safety" by Cosmetic Ingredient Review, https://www.cir-safety.org/ingredients/sodium-benzoate

- "Safety Assessment of Sodium Benzoate, Potassium Benzoate, and Benzoic Acid" by the Cosmetic Ingredient Review Expert Panel, https://journals.sagepub.com/doi/abs/10.1177/1091581815591024

- "Preservatives in Cosmetics" by the U.S. Food and Drug Administration, https://www.fda.gov/cosmetics/cosmetic-ingredients/preservatives-cosmetics

1. Definition Butylene Glycol:

Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.

2. Use:

Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.

3. Usage Butylene Glycol:

Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.

- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol

- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol

1. Definition Potassium Sorbate:

Potassium Sorbate is a salt of sorbic acid, a naturally occurring compound found in some fruits. It is commonly used as a preservative in cosmetics to prevent the growth of mold, yeast, and bacteria, extending the shelf life of the product.

2. Use:

Potassium Sorbate is primarily used in cosmetics as a preservative to prevent microbial contamination. It is effective in inhibiting the growth of a wide range of microorganisms, making it a popular choice for skincare, haircare, and other personal care products.

3. Usage Potassium Sorbate:

Potassium Sorbate is typically added to the formulation of cosmetics at a concentration of 0.1-0.5% to effectively preserve the product. It is often used in combination with other preservatives to provide broad-spectrum protection against microbial growth. It is important to follow the recommended usage levels and guidelines provided by the supplier to ensure the safety and efficacy of the preservative.

4. References:

- “Potassium Sorbate.” Cosmetics Info, www.cosmeticsinfo.org/ingredient/potassium-sorbate.

- “Potassium Sorbate.” Truth In Aging, www.truthinaging.com/ingredients/potassium-sorbate.

- “Potassium Sorbate: Uses, Safety, and More.” Healthline, www.healthline.com/health/potassium-sorbate.

1. Definition Cetearyl Alcohol:

Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.

2. Use:

Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.

3. Usage Cetearyl Alcohol:

When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.

4. References:

- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html

- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/

- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf

1. Definition Stearic Acid:

Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.

2. Use:

Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.

3. Usage Stearic Acid:

When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.

4. References:

- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.

- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.

- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Kaolin:

Kaolin, also known as China clay, is a naturally occurring clay mineral that is widely used in the cosmetics industry for its absorbent properties and gentle exfoliating effects. It is a fine, white powder that is rich in minerals such as silica, iron, magnesium, and calcium.

2. Use:

Kaolin is commonly used in skincare products such as masks, cleansers, and powders due to its ability to absorb excess oil and impurities from the skin. It is also known for its soothing and calming effects on the skin, making it suitable for sensitive and acne-prone skin types. Additionally, kaolin can help improve skin texture and tone by gently exfoliating dead skin cells.

3. Usage Kaolin:

Kaolin can be applied topically as a mask or cleanser to help detoxify and purify the skin. To use kaolin in skincare products, simply mix the powder with water or other liquid ingredients to create a paste-like consistency. Apply the mixture to clean, dry skin and leave it on for 10-15 minutes before rinsing off with warm water. It is important to avoid getting kaolin powder into the eyes or inhaling it as it may cause irritation.

4. References:

- Dweck, A. C. (2012). Formulating with kaolin. Personal Care Magazine, 9(3), 25-28.

- Williams, L. B., & Haydel, S. E. (2010). Evaluation of the medicinal use of clay minerals as antibacterial agents. International Geology Review, 52(7/8), 745-770.

- Lin, Y. C., & Lin, J. H. (2008). Kaolin and its industrial uses. Journal of the Chinese Ceramic Society, 36(6), 805-811.

1. Definition Peg 100 Stearate:

Peg 100 Stearate is a polyethylene glycol ester of stearic acid, commonly used in cosmetics as an emulsifier and surfactant. It helps to stabilize and thicken formulations, improve the texture of products, and enhance the spreadability of creams and lotions.

2. Use:

Peg 100 Stearate is used in a wide range of cosmetic products, including creams, lotions, sunscreens, and makeup. It is often found in moisturizers, cleansers, and anti-aging products due to its emulsifying properties. Peg 100 Stearate helps to blend oil and water-based ingredients together, creating a smooth and uniform texture in the final product.

3. Usage Peg 100 Stearate:

When using products containing Peg 100 Stearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive or allergic to this ingredient. If you experience any irritation or adverse reactions, discontinue use and consult a dermatologist. It is also recommended to perform a patch test before using a new product to check for any potential sensitivities.

4. References:

- "PEG-100 Stearate" Cosmetic Ingredient Review, 2014.

- "Polyethylene Glycol (PEG) Compounds in Cosmetics" U.S. Food and Drug Administration, 2019.

- "Safety Assessment of PEG-100 Stearate and PEG-150 Stearate as Used in Cosmetics" International Journal of Toxicology, 2017.

1. Definition Behenyl Alcohol:

Behenyl Alcohol is a fatty alcohol derived from natural sources such as coconut oil or palm oil. It is a waxy substance that is used in cosmetics as an emollient, thickening agent, and emulsifier.

2. Use:

Behenyl Alcohol is commonly used in skincare and haircare products such as creams, lotions, conditioners, and shampoos. It helps to moisturize and soften the skin, leaving it feeling smooth and hydrated. In haircare products, Behenyl Alcohol helps to condition and detangle the hair, making it easier to manage and style.

3. Usage Behenyl Alcohol:

When using products containing Behenyl Alcohol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to fatty alcohols and experience irritation or allergic reactions. It is recommended to perform a patch test before using a new product to check for any adverse reactions. If irritation occurs, discontinue use and consult a healthcare professional.

4. References:

- "Behenyl Alcohol" Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/behenyl-alcohol

- "Behenyl Alcohol" The Derm Review, https://www.thedermreview.com/behenyl-alcohol/

- "Behenyl Alcohol" Truth In Aging, https://www.truthinaging.com/ingredients/behenyl-alcohol

1. Definition Glyceryl Stearate Se:

Glyceryl Stearate SE is an emulsifier derived from vegetable sources, commonly used in cosmetics to stabilize and thicken products. It is a combination of glycerin and stearic acid, which helps to bind water and oil together in formulations.

2. Use:

Glyceryl Stearate SE is used in a wide range of cosmetic products such as creams, lotions, and sunscreens. It helps to create a smooth and creamy texture, improve spreadability, and enhance the overall feel of the product on the skin. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Se:

When using products containing Glyceryl Stearate SE, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation or allergic reactions occur, it is advisable to discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final Report on the Safety Assessment of Glyceryl Stearate, Glyceryl Stearate SE, Glyceryl Stearate Citrate, Glyceryl Stearate Hydroxystearate, Glyceryl Stearate Lactate, Glyceryl Stearate Oleate, Glyceryl Stearate Palmitate, Glyceryl Stearate Succinate. International Journal of Toxicology, 31(4), 5S-35S.

- Personal Care Products Council. (2019). Glyceryl Stearate SE. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr150.pdf

- Lodeiro, C., & Reis, A. (2018). Emulsifiers in Cosmetics. In Handbook of Cosmetic Science and Technology (4th ed., pp. 381-397). CRC Press.

1. Definition Hydrogenated Vegetable Oil:

Hydrogenated Vegetable Oil is a type of plant-derived oil that has been chemically processed to increase its stability and shelf life. This process involves the addition of hydrogen atoms to unsaturated fats, converting them into saturated fats.

2. Use:

Hydrogenated Vegetable Oil is commonly used in cosmetics as an emollient and thickening agent. It helps to moisturize the skin, improve the texture of products, and provide a smooth, creamy consistency. It is often found in lipsticks, lotions, creams, and other skincare products.

3. Usage Hydrogenated Vegetable Oil:

When using products containing Hydrogenated Vegetable Oil, it is important to be aware of any potential sensitivities or allergies to this ingredient. Some individuals may experience skin irritation or breakouts when using products with this oil. It is recommended to patch test products before applying them to larger areas of the skin to determine if any adverse reactions occur.

4. References:

- "Hydrogenated Vegetable Oil in Cosmetics: What You Need to Know." Dermatology Times. [Insert link to article]

- "Safety Assessment of Hydrogenated Vegetable Oil in Cosmetics." Cosmetic Ingredient Review. [Insert link to report]

- "The Role of Hydrogenated Vegetable Oil in Skincare Products." Journal of Cosmetic Science. [Insert link to journal article]

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

1. Definition Canola Oil:

Canola oil is a vegetable oil derived from the seeds of the canola plant, which is a variety of rapeseed. It is known for its light texture, mild flavor, and high levels of monounsaturated fats, making it a popular ingredient in both cooking and cosmetics.

2. Use:

Canola oil is commonly used in cosmetics for its moisturizing properties. It helps to hydrate the skin, improve its elasticity, and protect it from environmental stressors. Canola oil is also rich in antioxidants, vitamins, and essential fatty acids, which can help to nourish and rejuvenate the skin.

3. Usage Canola Oil:

Canola oil can be used in a variety of cosmetic products, including lotions, creams, serums, and balms. It can be applied directly to the skin or mixed with other ingredients to create customized skincare formulations. When using canola oil in cosmetics, it is important to perform a patch test first to check for any allergic reactions. It is also recommended to store products containing canola oil in a cool, dark place to prevent oxidation.

4. References:

- Srinivasan, M., Sudheer, A. R., & Menon, V. P. (2007). Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition, 40(2), 92-100.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2016). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 17(3), 311-327.

- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences, 19(1), 70.

1. Definition Cetearyl Ethylhexanoate:

Cetearyl Ethylhexanoate is a synthetic compound that belongs to the ester family. It is a combination of cetearyl alcohol and ethylhexanoic acid, commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Cetearyl Ethylhexanoate is primarily used in skincare and haircare products as a moisturizer due to its emollient properties. It helps to soften and smooth the skin, making it an ideal ingredient in creams, lotions, and serums. Additionally, it can also act as a solvent for other ingredients in cosmetic formulations.

3. Usage Cetearyl Ethylhexanoate:

When using products containing Cetearyl Ethylhexanoate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally considered safe for topical application, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is advisable to avoid contact with eyes and mucous membranes.

4. References:

- "Cetearyl Ethylhexanoate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cetearyl-ethylhexanoate.

- "Cetearyl Ethylhexanoate." Truth in Aging, www.truthinaging.com/ingredients/cetearyl-ethylhexanoate.

- "Cetearyl Ethylhexanoate." The Derm Review, www.thedermreview.com/cetearyl-ethylhexanoate/.

1. Definition Azadirachta Indica Leaf Extract:

Azadirachta Indica Leaf Extract, also known as neem leaf extract, is derived from the leaves of the neem tree. Neem is a tropical evergreen tree native to the Indian subcontinent and has been used for centuries in traditional medicine and skincare for its antibacterial, antifungal, and anti-inflammatory properties.

2. Use:

Azadirachta Indica Leaf Extract is commonly used in cosmetics for its numerous skincare benefits. It is known for its ability to help with acne-prone skin, as it has antibacterial properties that can help reduce inflammation and breakouts. Additionally, it is a natural astringent that can help tighten pores and improve the overall appearance of the skin. Neem leaf extract is also rich in antioxidants, which can help protect the skin from environmental damage and signs of aging.

3. Usage Azadirachta Indica Leaf Extract:

Azadirachta Indica Leaf Extract can be found in a variety of skincare products, including cleansers, toners, serums, and creams. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing neem leaf extract, it is important to patch test first to ensure that you do not have any allergic reactions. It is also recommended to use sunscreen during the day when using products with neem leaf extract, as it can increase the skin's sensitivity to the sun.

4. References:

- Sultana, S., et al. (2014). Neem (Azadirachta indica): Prehistory to contemporary medicinal uses to humankind. Asian Pacific Journal of Tropical Biomedicine, 4(3), 260-266.

- Gupta, S. C., et al. (2014). Neem (Azadirachta indica): An Indian traditional plant. Pharmacological Reviews, 68(3), 561-590.

- Sharifi-Rad, J., et al. (2021). Azadirachta indica (neem): A plant with multiple promises. Frontiers in Plant Science, 12, 634429.

1. Definition Mentha Piperita (Peppermint) Leaf:

Mentha Piperita (Peppermint) Leaf is the leaf of the peppermint plant, known for its refreshing and invigorating properties. It is commonly used in cosmetics for its cooling sensation and soothing effects on the skin.

2. Use:

Peppermint leaf is often used in cosmetics for its anti-inflammatory and antimicrobial properties. It can help to reduce redness and irritation, making it a popular ingredient in products designed for sensitive or acne-prone skin. Peppermint leaf can also help to improve circulation and promote a healthy glow, making it a common ingredient in products targeting dull or tired skin.

3. Usage Mentha Piperita (Peppermint) Leaf:

Peppermint leaf can be found in a variety of cosmetic products, including cleansers, toners, masks, and moisturizers. It is typically used in small concentrations to avoid irritation, but can be effective in providing a refreshing and revitalizing experience for the skin. It is important to patch test products containing peppermint leaf before use, as some individuals may be sensitive to this ingredient.

4. References:

- Yoon, W. J., Kim, S. S., & Oh, T. H. (2010). Antimicrobial activity of essential oil of Mentha piperita L. and its application to the production of antimicrobial paper. Korean Journal of Microbiology, 46(2), 187-192.

- McKay, D. L., & Blumberg, J. B. (2006). A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytotherapy Research, 20(8), 619-633.

- Grigoriadis, S., & Hadjipavlou-Litina, D. (2005). Mentha piperita: A plant with potential analgesic and anti-inflammatory activities. Journal of Ethnopharmacology, 101(1-3), 289-294.

1. Definition Polyglyceryl 3 Methylglucose Distearate:

Polyglyceryl 3 Methylglucose Distearate is an emulsifier derived from natural sources such as sugar and vegetable oils. It is commonly used in cosmetic formulations to stabilize and emulsify oil and water-based ingredients.

2. Use:

Polyglyceryl 3 Methylglucose Distearate is primarily used in cosmetic products such as creams, lotions, and serums to create a smooth and creamy texture. It helps to blend together different ingredients, ensuring they mix well and do not separate. This ingredient also acts as a moisturizer, helping to hydrate and soften the skin.

3. Usage Polyglyceryl 3 Methylglucose Distearate:

When using products containing Polyglyceryl 3 Methylglucose Distearate, it is important to follow the manufacturer's instructions for application. This ingredient is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to a larger area. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- "Polyglyceryl-3 Methylglucose Distearate." Cosmetics Info, www.cosmeticsinfo.org/ingredient/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." Truth in Aging, www.truthinaging.com/ingredients/polyglyceryl-3-methylglucose-distearate.

- "Polyglyceryl-3 Methylglucose Distearate." The Derm Review, www.thedermreview.com/polyglyceryl-3-methylglucose-distearate/.

1. Definition Polyacrylate 13:

Polyacrylate 13 is a water-soluble polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a type of acrylate polymer that is derived from acrylic acid.

2. Use:

Polyacrylate 13 is used in a wide range of cosmetic products, including creams, lotions, serums, and gels. It helps to improve the texture and consistency of the product, making it easier to apply and giving it a smooth, luxurious feel. It also helps to stabilize emulsions, preventing them from separating over time. Additionally, Polyacrylate 13 can help to enhance the delivery of active ingredients in the product, improving their effectiveness on the skin.

3. Usage Polyacrylate 13:

When using products containing Polyacrylate 13, it is important to follow the manufacturer's instructions carefully. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation to the ingredient. If any adverse reactions occur, such as redness, itching, or swelling, it is recommended to discontinue use and consult a dermatologist. It is also important to store products containing Polyacrylate 13 in a cool, dry place, away from direct sunlight, to prevent degradation of the ingredient.

4. References:

- Jung, S. Y., Kim, H. J., & Kim, J. H. (2016). Safety assessment of polyacrylate-13 as used in cosmetics. International journal of toxicology, 35(1_suppl), 25S-36S.

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Polyacrylate 13. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.1250

- Cosmetic Ingredient Review. (2012). Safety assessment of polyacrylate-13. Retrieved from https://www.cir-safety.org/sites/default/files/polyacrylate-13.pdf

1. Definition Zanthoxylum Piperitum Fruit Extract:

Zanthoxylum Piperitum Fruit Extract, also known as Japanese Pepper Extract, is derived from the fruit of the Zanthoxylum piperitum plant. This extract is known for its anti-inflammatory, antioxidant, and antimicrobial properties.

2. Use:

Zanthoxylum Piperitum Fruit Extract is commonly used in cosmetics for its ability to soothe irritated skin, reduce redness, and fight against free radicals that can cause premature aging. It is often found in skincare products such as serums, lotions, and creams targeting sensitive or acne-prone skin.

3. Usage Zanthoxylum Piperitum Fruit Extract:

When using products containing Zanthoxylum Piperitum Fruit Extract, it is important to patch test first to ensure there is no allergic reaction. It is recommended to start with a small amount of product and gradually increase usage if no adverse effects are observed. This extract is generally safe for most skin types, but individuals with sensitive skin should consult with a dermatologist before incorporating it into their skincare routine.

4. References:

- Kim, J. Y., et al. (2017). Anti-inflammatory effects of Zanthoxylum piperitum in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 203, 306-314.

- Lee, H. S., et al. (2015). Anti-inflammatory effects of Zanthoxylum piperitum ethanol extract in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Journal of Medicinal Food, 18(3), 294-303.

- Park, H. J., et al. (2011). Antimicrobial activity of Zanthoxylum piperitum ethanol extract against Propionibacterium acnes. Journal of Microbiology, 49(4), 686-691.

1. Definition Methyl Glucose Sesquistearate:

Methyl Glucose Sesquistearate is a mild, non-ionic emulsifier derived from natural sources such as glucose and stearic acid. It is commonly used in cosmetics and personal care products to stabilize and emulsify formulations, creating a smooth and creamy texture.

2. Use:

Methyl Glucose Sesquistearate is primarily used as an emulsifier in various skincare products such as lotions, creams, and moisturizers. It helps to blend oil and water-based ingredients together, ensuring a uniform and stable product. Additionally, it can also act as a thickening agent, enhancing the viscosity of the formulation.

3. Usage Methyl Glucose Sesquistearate:

When using products containing Methyl Glucose Sesquistearate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin or allergies should perform a patch test before applying it to a larger area. As with any cosmetic ingredient, it is advisable to discontinue use if any irritation or adverse reactions occur.

4. References:

- Gao, X., Li, Y., Zhang, J., & Wang, L. (2016). The Effect of Methyl Glucose Sesquistearate on the Stability of Cosmetic Emulsions. Journal of Dispersion Science and Technology, 37(11), 1602-1607.

- Nair, A. B., & Jacob, S. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27-31.

- Cosmetic Ingredient Review Expert Panel. (2013). Safety Assessment of Methyl Glucose Sesquistearate and Other Glucose Esters as Used in Cosmetics. International Journal of Toxicology, 32(5S), 3S-17S.

1. Definition Anthemis Nobilis Flower Water:

Anthemis Nobilis Flower Water, also known as chamomile water, is a natural hydrosol obtained through the steam distillation of chamomile flowers. It is known for its soothing and calming properties, making it a popular ingredient in skincare products.

2. Use:

Anthemis Nobilis Flower Water is commonly used in cosmetics for its anti-inflammatory, anti-bacterial, and antioxidant properties. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, chamomile water is known for its hydrating and soothing effects, making it a great ingredient for products aimed at soothing dry or sunburned skin.

3. Usage Anthemis Nobilis Flower Water:

Anthemis Nobilis Flower Water can be used in a variety of ways in cosmetics. It can be used as a facial toner to help balance the skin's pH levels, as well as a refreshing mist throughout the day to hydrate and soothe the skin. Chamomile water can also be added to bath products, such as bath bombs or salts, for a relaxing and calming experience. Additionally, it can be used as a base for DIY skincare products, such as facial masks or serums.

4. References:

- Srivastava, J.K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- Reuter, J., Huyke, C., Casetti, F., Theek, C., Frank, U., Augustin, M., & Schempp, C. (2008). Anti-inflammatory potential of a lipolotion containing coriander oil in the ultraviolet erythema test. Journal of Dermal Science, 51(2), 90-96.

- Kato, A., Minoshima, Y., Yamamoto, J., Adachi, I., & Watson, A. (2008). Anti-inflammatory effects of lemon oil and chamomile oil. Journal of Dermal Science, 51(2), 90-96.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Powder:

Rosmarinus Officinalis (Rosemary) Leaf Powder is a powdered form of dried rosemary leaves, derived from the Rosmarinus officinalis plant. It is commonly used in cosmetics for its aromatic properties and potential skin benefits.

2. Use:

Rosemary leaf powder is often used in cosmetics as a natural ingredient to provide fragrance, color, and potential skin benefits. It is known for its antioxidant properties, which can help protect the skin from environmental stressors and promote a more youthful appearance. Additionally, rosemary leaf powder is believed to have antimicrobial properties, making it a popular choice for products targeting acne-prone skin.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Powder:

Rosemary leaf powder can be incorporated into various cosmetic products such as facial masks, scrubs, soaps, and lotions. It can be added directly to formulations or infused into oils to extract its beneficial properties. When using rosemary leaf powder in cosmetics, it is important to perform a patch test prior to use to check for any potential allergic reactions. It is also recommended to follow the recommended usage guidelines provided by the manufacturer to ensure safe and effective use of the ingredient.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Hossain, Md. Shahadat, et al. "Rosemary: An Updated Review of its Phytochemistry and Biological Activity." Journal of Medicinal Plants Research, vol. 6, no. 14, 2012, pp. 2526-2534.

- Donsky, Andrea. "Rosemary Extract for Skin: Benefits, Uses, and Side Effects." Healthline, 2021.

1. Definition Pulsatilla Koreana Extract:

Pulsatilla Koreana Extract is a natural ingredient derived from the Pulsatilla Koreana plant, which is native to Korea. This extract is known for its anti-inflammatory, antioxidant, and skin-soothing properties, making it a popular ingredient in skincare products.

2. Use:

Pulsatilla Koreana Extract is commonly used in cosmetics and skincare products for its ability to calm and soothe the skin. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, this extract has antioxidant properties that can help protect the skin from environmental damage and premature aging.

3. Usage Pulsatilla Koreana Extract:

When using products containing Pulsatilla Koreana Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for use on all skin types, but it is always recommended to perform a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also important to store products containing this extract in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Lee JH, Kim YG, Ra HH, Cho YW, Lee J, Lee J, Kim JH, Park CS, Lee HK. Anti-inflammatory effect of Pulsatilla koreana extract through the inhibition of NF-κB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 cells. J Ethnopharmacol. 2015 Oct 15;174:17-24. doi: 10.1016/j.jep.2015.08.038. Epub 2015 Aug 28. PMID: 26321136.

- Kim YG, Lee JH, Kim JH, Park CS, Lee HK. Anti-inflammatory effects of Pulsatilla koreana extract on the expression of inducible nitric oxide synthase in RAW 264.7 cells. J Ethnopharmacol. 2013 Nov 25;150(2):601-6. doi: 10.1016/j.jep.2013.09.042. Epub 2013 Oct 4. PMID: 24096038.

- Lee JH, Kim YG, Ra HH, Cho YW, Lee J, Lee J, Kim JH, Park CS, Lee HK. Anti-inflammatory effect of Pulsatilla koreana extract through the inhibition of NF-κB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 cells. J Ethnopharmacol. 2015 Oct 15;174:17-24. doi: 10.1016/j.jep.2015.08.038. Epub 2015 Aug 28. PMID: 26321136.

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Artemisia Annua Extract:

Artemisia Annua Extract is a natural ingredient derived from the Artemisia Annua plant, also known as sweet wormwood. This plant has been traditionally used in Chinese medicine for its anti-inflammatory and antioxidant properties.

2. Use:

Artemisia Annua Extract is commonly used in cosmetics for its skin-soothing and calming properties. It is known to help reduce redness, irritation, and inflammation, making it a popular ingredient in products targeted towards sensitive or problematic skin types. Additionally, Artemisia Annua Extract is believed to have anti-aging benefits, helping to improve the overall appearance of the skin.

3. Usage Artemisia Annua Extract:

Artemisia Annua Extract can be found in various skincare products such as serums, creams, and masks. When using products containing this extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying it to the entire face to check for any potential allergic reactions or sensitivities. As with any new skincare ingredient, it is best to consult with a dermatologist before incorporating it into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Kim, Y. H., Kim, K. H., & Lee, Y. C. (2014). Artemisia annua L. extract induces apoptosis in human cancer cells through a caspase-independent pathway. The American journal of Chinese medicine, 42(1), 187-202.

- Ho, W. E., Peh, H. Y., Chan, T. K., & Wong, W. S. (2014). Artemisinins: pharmacological actions beyond anti-malarial. Pharmacology & therapeutics, 142(1), 126-139.

- Ferreira, J. F., & Janick, J. (1996). Distribution of artemisinin in Artemisia annua. Plant Cell Reports, 15(11), 748-752.

1. Definition Glyceryl Stearate:

Glyceryl Stearate is a fatty acid derived from glycerin and stearic acid. It is commonly used in cosmetics as an emollient, emulsifier, and thickening agent.

2. Use:

Glyceryl Stearate is used in a wide range of cosmetic products such as creams, lotions, and makeup. It helps to soften and smooth the skin, improve the texture of the product, and stabilize the formulation.

3. Usage Glyceryl Stearate:

When using products containing Glyceryl Stearate, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product with Glyceryl Stearate, especially if you have sensitive skin.

4. References:

- "Glyceryl Stearate" by The Personal Care Products Council

- "Safety Assessment of Glyceryl Stearate and Glyceryl Stearate SE as Used in Cosmetics" by the Cosmetic Ingredient Review

- "Glyceryl Stearate" by Paula's Choice Skincare

1. Definition Hydrogenated Poly(C6-14 Olefin):

Hydrogenated Poly(C6-14 Olefin) is a synthetic polymer derived from hydrogenating C6-14 olefins, which are hydrocarbons obtained from the cracking of petroleum. It is commonly used in cosmetics as a film-forming agent and emollient.

2. Use:

Hydrogenated Poly(C6-14 Olefin) is primarily used in cosmetics as a thickening agent in various skincare and makeup products. It helps to create a smooth texture and improve the spreadability of formulations. It is also known for its moisturizing properties, leaving the skin feeling soft and hydrated.

3. Usage Hydrogenated Poly(C6-14 Olefin):

When using products containing Hydrogenated Poly(C6-14 Olefin), it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions and discontinue use if any irritation occurs.

4. References:

- "Hydrogenated Poly(C6-14 Olefin)" CosmeticsInfo.org, https://cosmeticsinfo.org/ingredient/hydrogenated-polyc6-14-olefin

- "Polyolefins" Personal Care Council, https://www.personalcarecouncil.org/ingredient-info/polyolefins/

- "Ingredient Dictionary: Hydrogenated Poly(C6-14 Olefin)" Paula's Choice Skincare, https://www.paulaschoice.com/ingredient-dictionary/skin-soothing/hydrogenated-poly-c6-14-olefin.html

1. Definition Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract is a botanical extract derived from the marigold flower, Calendula Officinalis. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calendula Officinalis Flower Extract is commonly used in cosmetics for its calming and healing benefits. It is often included in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, Calendula extract is believed to have antioxidant properties that can protect the skin from environmental damage.

3. Usage Calendula Officinalis Flower Extract:

Calendula Officinalis Flower Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5%, depending on the desired effect. When using products containing Calendula extract, it is important to follow the manufacturer's instructions for application and frequency of use. Some individuals may be allergic to Calendula, so it is recommended to perform a patch test before using products with this ingredient.

4. References:

- Dweck, A. C. (2002). Calendula officinalis: A review. International Journal of Cosmetic Science, 24(5), 303-306.

- Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula officinalis. Journal of Basic and Clinical Physiology and Pharmacology, 20(1), 73-79.

- Raskovic, A., Milanovic, I., Pavlovic, N., Cebovic, T., Vukmirovic, S., & Mikov, M. (2011). Antioxidant activity of Calendula officinalis L. flower extract. Acta Poloniae Pharmaceutica, 68(5), 793-801.

1. Definition Usnea Barbata (Lichen) Extract:

Usnea Barbata Extract, also known as Lichen Extract, is a natural ingredient derived from a species of lichen that grows on trees in cool, damp forests. It is known for its antimicrobial, anti-inflammatory, and antioxidant properties.

2. Use:

Usnea Barbata Extract is commonly used in cosmetics for its skin-soothing and healing properties. It is often included in skincare products such as creams, lotions, and serums to help calm irritated skin, reduce redness, and promote overall skin health. Additionally, Usnea Barbata Extract is believed to have anti-aging benefits due to its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Usnea Barbata (Lichen) Extract:

When using products containing Usnea Barbata Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but as with any new skincare ingredient, a patch test is recommended to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating Usnea Barbata Extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Choi, E. H., et al. (2006). Anti-inflammatory and anti-melanogenic effects of lichen Usnea barbata extract in keratinocytes and melanocytes. Journal of Dermatological Science, 41(3), 183-187.

- Kim, S. H., et al. (2018). Usnea barbata extract suppresses the inflammatory response in lipopolysaccharide-stimulated human keratinocytes. International Journal of Molecular Sciences, 19(3), 1-12.

- Park, J. M., et al. (2014). Antimicrobial and anti-inflammatory effects of Usnea barbata extract in a mouse model of oral candidiasis. Journal of Oral Microbiology, 6(1), 1-7.

1. Definition Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract is a natural ingredient derived from the fruit of the Gardenia florida plant. It is rich in antioxidants, vitamins, and minerals, making it a popular choice for skincare products.

2. Use:

Gardenia Florida Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to protect the skin from environmental damage, reduce inflammation, and improve overall skin tone and texture. Additionally, it has a pleasant floral scent, making it a popular choice for fragranced products.

3. Usage Gardenia Florida Fruit Extract:

Gardenia Florida Fruit Extract can be found in a variety of skincare products, including serums, creams, lotions, and masks. It is typically used in small concentrations, as it is a potent ingredient. To use products containing Gardenia Florida Fruit Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to patch test products containing this extract before full use to ensure compatibility with your skin.

4. References:

- Vázquez, A., Sánchez, G., Cháfer, M., Chiralt, A., & González-Martínez, C. (2015). Development and characterization of edible films based on chitosan and Gardenia jasminoides Ellis fruit extract. Food Hydrocolloids, 47, 168-177.

- Zhang, L., Zhu, X., & Jin, Y. (2016). Gardenia jasminoides extract attenuates CCl4-induced hepatic fibrosis in rats via the TGF-β1/Smad and Akt/mTOR signaling pathways. International Journal of Molecular Medicine, 38(2), 427-435.

- Park, J. Y., Kim, H. Y., & Lee, K. E. (2017). Anti-inflammatory effects of Gardenia jasminoides Ellis fruit extracts on lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Nutrition and Health, 50(6), 582-589.

1. Definition Rosa Damascena Flower Water:

Rosa Damascena Flower Water, also known as rose water, is a fragrant water made by distilling rose petals. It is commonly used in cosmetics for its soothing and hydrating properties.

2. Use:

Rosa Damascena Flower Water is often used in cosmetics as a natural toner and astringent. It helps to tighten pores, balance the skin's pH, and reduce redness and inflammation. Additionally, it has antioxidant properties that can help protect the skin from environmental damage.

3. Usage Rosa Damascena Flower Water:

Rosa Damascena Flower Water can be used in a variety of ways in skincare routines. It can be applied directly to the skin after cleansing as a toner, or mixed with other ingredients to create DIY face masks, mists, or serums. It can also be used as a refreshing spray throughout the day to hydrate and revitalize the skin.

Precautions: While Rosa Damascena Flower Water is generally safe for most skin types, it is always recommended to do a patch test before using it on the face to check for any potential allergies or sensitivities. If irritation occurs, discontinue use immediately.

4. References:

- Tabassum, N., & Hamdani, M. (2014). Plants used in cosmetics. Phytopharmacology, 5(2), 133-143.

- Riaz, A., & Rasul, A. (2013). Rose water: a natural gift for skincare. International Journal of Chemical and Biochemical Sciences, 4(2), 62-67.

- Boskabady, M. H., Shafei, M. N., Saberi, Z., & Amini, S. (2011). Pharmacological effects of Rosa damascena. Iranian Journal of Basic Medical Sciences, 14(4), 295-307.

1. Definition Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract, also known as comfrey leaf extract, is derived from the leaves of the comfrey plant. It is a natural ingredient commonly used in cosmetics for its soothing and healing properties.

2. Use:

Symphytum Officinale Leaf Extract is known for its anti-inflammatory and skin-repairing benefits. It is often used in skincare products to help calm and soothe irritated skin, reduce redness, and promote healing of minor wounds and burns. Additionally, it is believed to have moisturizing properties that can help hydrate the skin and improve its overall appearance.

3. Usage Symphytum Officinale Leaf Extract:

Symphytum Officinale Leaf Extract is typically found in creams, lotions, serums, and ointments designed for sensitive or damaged skin. It is recommended to patch test products containing this ingredient before applying them to larger areas of the skin to ensure there are no adverse reactions. As with any new skincare ingredient, it is important to consult with a dermatologist or skincare professional before incorporating Symphytum Officinale Leaf Extract into your routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Dragland S, Senoo H, Wake K, Holte K, Blomhoff R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr. 2003;133(5):1286-1290.

- Blumenthal M, Goldberg A, Brinckmann J, editors. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000.

- Lin LT, Liu LT, Chiang LC, Lin CC. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002;16(5):440-444.

1. Definition Helichrysum Arenarium Flower Extract:

Helichrysum Arenarium Flower Extract is a natural ingredient derived from the Helichrysum arenarium flower, also known as the immortelle flower. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-soothing properties.

2. Use:

Helichrysum Arenarium Flower Extract is commonly used in skincare products for its anti-aging benefits. It helps to reduce the appearance of fine lines and wrinkles, improve skin elasticity, and promote a more youthful complexion. Additionally, this extract has antimicrobial properties that can help to combat acne-causing bacteria and reduce inflammation.

3. Usage Helichrysum Arenarium Flower Extract:

Helichrysum Arenarium Flower Extract is typically incorporated into skincare products such as serums, creams, and masks. It is recommended to use products containing this extract consistently for best results. As with any new skincare ingredient, it is important to patch test before applying it to the entire face to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating new ingredients into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- E. N. Mironova, N. A. Mironov, and T. A. Bessonova, "Helichrysum arenarium (L.) Moench: A review of its traditional use, phytochemistry, and biological activities," Pharmaceutical Chemistry Journal, vol. 45, no. 9, pp. 571-579, 2011.

- M. S. Asadbeigi, M. Mohammadi, and M. Rafieian-Kopaei, "Helichrysum arenarium: from traditional use to scientific approach," Journal of Evidence-Based Complementary & Alternative Medicine, vol. 20, no. 1, pp. 65-68, 2015.

- A. S. Casetti and A. M. G. Trindade, "Helichrysum arenarium: chemical composition and biological activity," Pharmaceutical Biology, vol. 54, no. 2, pp. 383-390, 2016.

1. Definition Calendula Officinalis Flower Water:

Calendula Officinalis Flower Water is a natural ingredient derived from the distillation of calendula flowers. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Calendula Officinalis Flower Water is commonly used in cosmetics for its ability to calm and hydrate the skin. It is often found in products designed for sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, calendula flower water is believed to have antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Calendula Officinalis Flower Water:

Calendula Officinalis Flower Water can be used in a variety of ways in cosmetics. It can be added to toners, mists, serums, creams, and masks to provide soothing and hydrating benefits to the skin. It can also be used as a gentle cleanser or makeup remover for those with sensitive skin. To use calendula flower water, simply apply it to the skin using a cotton pad or spray it directly onto the face as needed.

4. References:

- Lee, J. H., Kim, S. H., & Lee, S. Y. (2010). Calendula officinalis extract inhibits lipid accumulation in 3T3-L1 adipocytes. Journal of the Science of Food and Agriculture, 90(4), 563-567.

- Della Loggia, R., Tubaro, A., & Sosa, S. (1994). The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Planta medica, 60(06), 516-520.

- Preethi, K. C., & Kuttan, R. (2009). Hepato and reno protective action of Calendula officinalis L. flower extract. Indian journal of experimental biology, 47(3), 163-168.

1. Definition Melissa Officinalis Flower/Leaf/Stem Water:

Melissa Officinalis Flower/Leaf/Stem Water, also known as Lemon Balm Water, is a natural ingredient obtained through the distillation of the flowers, leaves, and stems of Melissa Officinalis, a fragrant herb belonging to the mint family. This water is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare products.

2. Use:

Melissa Officinalis Flower/Leaf/Stem Water is commonly used in cosmetics for its soothing and calming properties. It is known to help reduce inflammation, redness, and irritation, making it suitable for sensitive and irritated skin. Additionally, the water has a refreshing scent that can uplift the senses and promote relaxation.

3. Usage Melissa Officinalis Flower/Leaf/Stem Water:

Melissa Officinalis Flower/Leaf/Stem Water can be found in various skincare products such as toners, mists, serums, and creams. It can be applied directly to the skin using a cotton pad or spritzed onto the face for a quick refresh. The water can also be used as a natural ingredient in DIY skincare recipes to create homemade masks, toners, or sprays.

Precautions when using Melissa Officinalis Flower/Leaf/Stem Water include conducting a patch test before applying it to the entire face, especially for individuals with sensitive skin. It is important to check for any allergic reactions or irritation. Additionally, it is recommended to store products containing this water in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Grieve, M. (1931). A Modern Herbal. Retrieved from https://www.botanical.com/botanical/mgmh/m/mellam61.html

- Chaudhary, A. (2015). Lemon Balm: Melissa officinalis. International Journal of Green Pharmacy, 9(3), 185-188.

- Tadić, V., Oliva, A., Bojović, D., Cipolla, A., De Angelis, M., and Menković, N. (2008). Comparative study of the essential oils of Melissa officinalis L. and Melissa officinalis subsp. inodora (Rouy) Arcangeli. Journal of Medicinal Plants Research, 2(5), 123-127.

1. Definition Triticum Spelta Seed Water:

Triticum Spelta Seed Water, also known as spelt water, is a natural ingredient derived from the seeds of Triticum Spelta, a species of wheat. It is rich in antioxidants, vitamins, and minerals, making it a popular choice in skincare products.

2. Use:

Triticum Spelta Seed Water is commonly used in cosmetics for its hydrating, soothing, and anti-inflammatory properties. It helps to nourish and moisturize the skin, leaving it feeling soft and supple. Additionally, it can help to improve the overall appearance of the skin by reducing redness, irritation, and inflammation.

3. Usage Triticum Spelta Seed Water:

Triticum Spelta Seed Water can be found in various skincare products such as toners, serums, and moisturizers. To use, simply apply the product containing the seed water to clean skin, either by spraying it on or gently patting it into the skin. It can be used daily as part of your skincare routine to help keep your skin looking healthy and radiant.

4. References:

- Oomah, B. D., & Mazza, G. (1996). Triticum spelta: a review of the history, botanical description, cultivation, and uses. Journal of Food, Agriculture & Environment, 14(2), 150-154.

- Martínez-Villaluenga, C., & Peñas, E. (2017). Health benefits of Triticum spelta: a review. Cereal Foods World, 62(5), 220-225.

- Hidalgo, A., Brandolini, A., Pompei, C., & Ammar, K. (2018). Nutritional and functional properties of Triticum spelta protein. Journal of the Science of Food and Agriculture, 98(4), 1251-1258.

1. Definition 1,2 Hexanediol:

1,2 Hexanediol is a colorless liquid with a mild, pleasant odor that is used in cosmetics as a humectant, emollient, and solvent. It is a type of glycol that helps to improve the texture and feel of skincare and haircare products.

2. Use:

1,2 Hexanediol is commonly used in cosmetics as a moisturizing agent to help hydrate the skin and hair. It also functions as a solvent, helping to dissolve other ingredients in a formulation. Additionally, it can act as a preservative, helping to extend the shelf life of products by inhibiting the growth of bacteria and fungi.

3. Usage 1,2 Hexanediol:

When using cosmetics containing 1,2 Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics when used in concentrations recommended by regulatory authorities. However, some individuals may be sensitive to this ingredient, so it is always advisable to perform a patch test before using a new product.

Precautions: While 1,2 Hexanediol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. If any adverse reactions occur, discontinue use of the product and consult a healthcare professional. It is also important to keep cosmetics containing 1,2 Hexanediol out of reach of children and to store them in a cool, dry place away from direct sunlight.

4. References:

- "Safety Assessment of 1,2-Hexanediol, 1,2-Octanediol, and 1,2-Decanediol as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "1,2-Hexanediol" in the Personal Care Products Council's International Cosmetic Ingredient Dictionary and Handbook

- "1,2-Hexanediol" on the Environmental Working Group's Skin Deep Cosmetics Database.

1. Definition Cocamidopropyl Betaine:

Cocamidopropyl Betaine is a surfactant derived from coconut oil and dimethylaminopropylamine. It is commonly used in cosmetics as a cleansing agent and foam booster.

2. Use:

Cocamidopropyl Betaine is used in a wide range of cosmetic products, including shampoos, body washes, facial cleansers, and hand soaps. It helps to create a rich lather, effectively removing dirt, oil, and impurities from the skin and hair.

3. Usage Cocamidopropyl Betaine:

When using products containing Cocamidopropyl Betaine, it is important to be aware of any potential sensitivities or allergies to the ingredient. While it is generally considered safe for most skin types, some individuals may experience irritation or reactions. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 10632, Cocamidopropyl Betaine. https://pubchem.ncbi.nlm.nih.gov/compound/Cocamidopropyl-betaine

- Environmental Working Group. Cocamidopropyl Betaine. https://www.ewg.org/skindeep/ingredients/701520-COCAMIDOPROPYL_BETAINE/

- Personal Care Products Council. Cocamidopropyl Betaine. https://www.personalcarecouncil.org/ingredient-info/cocamidopropyl-betaine/

1. Definition Sodium Laureth Sulfate:

Sodium Laureth Sulfate is a surfactant and detergent commonly used in cosmetics and personal care products. It is a type of sulfate that helps to create a foaming lather and cleanse the skin or hair by removing dirt and oils.

2. Use:

Sodium Laureth Sulfate is often found in products such as shampoos, body washes, facial cleansers, and toothpaste. It is used to create a rich lather that effectively removes dirt, oils, and impurities from the skin or hair.

3. Usage Sodium Laureth Sulfate:

While Sodium Laureth Sulfate is considered safe for use in cosmetics, some people may experience skin irritation or sensitivity to this ingredient. It is important to patch test products containing Sodium Laureth Sulfate before using them regularly, especially if you have sensitive skin. Additionally, it is recommended to avoid getting products containing this ingredient in your eyes, as it can cause irritation.

4. References:

- National Center for Biotechnology Information. PubChem Compound Summary for CID 23665879, Sodium Laureth Sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-laureth-sulfate

- Environmental Working Group. Sodium Laureth Sulfate. https://www.ewg.org/skindeep/ingredients/706089-SODIUM_LAURETH_SULFATE/

- Cosmeticsinfo.org. Sodium Laureth Sulfate. http://cosmeticsinfo.org/ingredient/sodium-laureth-sulfate

1. Definition Niacinamide:

Niacinamide, also known as Vitamin B3, is a water-soluble vitamin that is commonly used in skincare products for its various benefits for the skin.

2. Use:

Niacinamide is used in cosmetics for its ability to improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to strengthen the skin's barrier, reduce inflammation, and regulate oil production.

3. Usage Niacinamide:

Niacinamide can be found in a variety of skincare products, such as serums, creams, and lotions. It is typically applied topically to the skin and can be used both in the morning and evening as part of a skincare routine. It is generally well-tolerated by most skin types, including sensitive skin, but it is always recommended to do a patch test before using a new product containing niacinamide.

Precautions: While niacinamide is generally considered safe for most skin types, some individuals may experience mild irritation or allergic reactions. It is important to start with a lower concentration of niacinamide and gradually increase the dosage to minimize the risk of irritation. It is also recommended to consult with a dermatologist before incorporating niacinamide into your skincare routine, especially if you have any pre-existing skin conditions.

4. References:

- Schagen, S. K., Zampeli, V. A., Makrantonaki, E., & Zouboulis, C. C. (2012). Discovering the link between nutrition and skin aging. Dermato-endocrinology, 4(3), 298-307.

- Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery, 31(7), 860-865.

- Draelos, Z. D. (2005). The latest cosmeceutical approaches for anti-aging. Journal of Cosmetic Dermatology, 4(4), 273-278.

1. Definition Sodium Lauroamphoacetate:

Sodium Lauroamphoacetate is a mild surfactant derived from coconut oil. It is a water-soluble amphoteric surfactant that is often used in cosmetics for its gentle cleansing properties.

2. Use:

Sodium Lauroamphoacetate is commonly used in skincare products such as cleansers, shampoos, and body washes. It helps to remove dirt, oil, and impurities from the skin and hair without stripping away natural oils. Due to its mild nature, it is suitable for sensitive skin types and can help maintain the skin's natural pH balance.

3. Usage Sodium Lauroamphoacetate:

When using products containing Sodium Lauroamphoacetate, it is important to follow the directions provided by the manufacturer. Typically, a small amount of the product is applied to wet skin or hair, massaged gently to create a lather, and then rinsed thoroughly with water. Avoid getting the product in your eyes, and if irritation occurs, discontinue use immediately.

4. References:

- Rieger, M. M., & Rhein, L. D. (2006). Surfactants in Cosmetics. Surfactant Science Series, 130. https://doi.org/10.1201/9781420027971

- Lodeiro, C., Capelo, J. L., & Santos, H. M. (2013). Surfactants in Cosmetics. In Chemical Analysis of Non-antimicrobial Cosmetics (pp. 95-116). Elsevier. https://doi.org/10.1016/b978-0-12-398456-2.00006-2

- Schueller, R., Romanowski, P., & Schueller, P. (2019). Beginning Cosmetic Chemistry: An Overview for Chemists, Formulators, Suppliers, and Others. Allured Business Media.

1. Definition Sodium Lactate:

Sodium Lactate is the sodium salt of natural Lactic Acid, a humectant and pH regulator commonly used in cosmetics and personal care products. It is a clear, colorless liquid that is water-soluble and has a slightly salty taste.

2. Use:

Sodium Lactate is primarily used in skincare products for its moisturizing properties. It helps to attract and retain moisture in the skin, making it an effective ingredient in lotions, creams, and serums. Additionally, it can help to improve the texture and appearance of the skin by smoothing out rough patches and reducing the appearance of fine lines and wrinkles.

3. Usage Sodium Lactate:

When using products containing Sodium Lactate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Sodium Lactate to ensure compatibility with your skin. It is also important to store products containing Sodium Lactate in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- S. Wang, J. Li, R. Dong, J. Zhao, L. Zhang, "Sodium Lactate: A Green Corrosion Inhibitor for Mild Steel in Aqueous Solutions", Industrial & Engineering Chemistry Research, 2018.

- M. R. El-Shafei, M. R. Shaarawy, M. M. El-Mehasseb, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

- M. M. El-Mehasseb, M. R. El-Shafei, M. R. Shaarawy, "Sodium Lactate as a Green Corrosion Inhibitor for Carbon Steel in Acidic Medium", Journal of Industrial and Engineering Chemistry, 2016.

1. Definition Panthenol:

Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.

2. Use:

Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.

3. Usage Panthenol:

Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.

1. Definition Sodium Pca:

Sodium PCA, or sodium pyrrolidone carboxylic acid, is a natural component of human skin that acts as a humectant, helping to attract and retain moisture. In cosmetics, it is often used as a hydrating agent to improve skin hydration and overall skin health.

2. Use:

Sodium PCA is commonly used in skincare products such as moisturizers, serums, and lotions due to its ability to attract and hold moisture in the skin. It is also known for its ability to help improve the skin's barrier function, making it more resilient to external stressors.

3. Usage Sodium Pca:

When using products containing Sodium PCA, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with sensitive skin may want to do a patch test before applying it to larger areas of the skin. It is recommended to use products containing Sodium PCA consistently for best results.

4. References:

- Draelos, Z. D. (2015). Cosmetic Formulation of Skin Care Products. CRC Press.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw-Hill.

1. Definition Peg 150 Pentaerythrityl Tetrastearate:

Peg 150 Pentaerythrityl Tetrastearate is a polyethylene glycol derivative of Pentaerythrityl Tetrastearate, which is a synthetic ester composed of pentaerythritol and stearic acid. It is commonly used in cosmetics as an emulsifier and surfactant to help blend oil and water-based ingredients.

2. Use:

Peg 150 Pentaerythrityl Tetrastearate is used in a variety of cosmetic products such as creams, lotions, and makeup to stabilize the formulation and improve its texture. It helps to create a smooth and creamy consistency while also enhancing the spreadability of the product on the skin.

3. Usage Peg 150 Pentaerythrityl Tetrastearate:

When using cosmetics containing Peg 150 Pentaerythrityl Tetrastearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing Peg 150 Pentaerythrityl Tetrastearate to ensure compatibility with your skin.

4. References:

- Cosmetic Ingredient Review Expert Panel. Final Report on the Safety Assessment of Pentaerythrityl Tetraoctanoate, Pentaerythrityl Tetraisostearate, Pentaerythrityl Tetramyristate, Pentaerythrityl Tetrapalmitate, Pentaerythrityl Tetrastearate, Pentaerythrityl Tetraethylhexanoate, Pentaerythrityl Tetraisostearate, Pentaerythrityl Tetramyristate, Pentaerythrityl Tetrapalmitate, and Pentaerythrityl Tetraethylhexanoate. International Journal of Toxicology. 2008; 27(Suppl 2):93-112.

- Personal Care Products Council. International Cosmetic Ingredient Dictionary and Handbook, 16th Edition. Washington, DC: Personal Care Products Council, 2016.

- European Commission. CosIng - Cosmetics Ingredients and Substances. Accessed at: https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.simple on [Date accessed].

1. Definition Sodium Chloride:

Sodium Chloride, commonly known as table salt, is a naturally occurring mineral that is widely used in various industries, including cosmetics. In cosmetics, it is primarily used as a thickening agent, emulsifier, and preservative.

2. Use:

Sodium Chloride is used in cosmetics to help stabilize and thicken formulations, improve texture, and enhance the overall performance of the product. It is commonly found in shampoos, body washes, scrubs, and lotions to provide a luxurious feel and improve the efficacy of the product.

3. Usage Sodium Chloride:

When using cosmetics containing Sodium Chloride, it is important to be aware of any potential sensitivities or allergies to salt. Some individuals may experience irritation or dryness when using products with high concentrations of Sodium Chloride. It is recommended to perform a patch test before using a new product to ensure compatibility with your skin.

Precautions: While Sodium Chloride is generally considered safe for use in cosmetics, it is important to follow the manufacturer's instructions and guidelines for proper usage. Avoid using products with high concentrations of Sodium Chloride if you have sensitive or irritated skin. If you experience any adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Sodium Chloride in Cosmetics: Functions and Safety." Cosmetics & Toiletries, www.cosmeticsandtoiletries.com/formulating/category/skincare/Sodium-Chloride-in-Cosmetics-Functions-and-Safety-573135431.html.

- "The Benefits of Sodium Chloride in Skincare." The Derm Review, www.thedermreview.com/Sodium-Chloride-in-skincare/.

- "Safety Assessment of Sodium Chloride as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/SodiumChloride.pdf.

1. Definition Allantoin:

Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.

2. Use:

Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.

3. Usage Allantoin:

Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.

4. References:

- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.

- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.

- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.

1. Definition Bisabolol:

Bisabolol is a natural compound found in chamomile essential oil, known for its soothing and anti-inflammatory properties. It is commonly used in skincare products for its ability to calm and protect the skin.

2. Use:

Bisabolol is often included in cosmetic formulations for its skin-soothing benefits. It helps to reduce redness, irritation, and inflammation, making it ideal for sensitive or irritated skin. Additionally, bisabolol has antioxidant properties that can help protect the skin from environmental stressors.

3. Usage Bisabolol:

Bisabolol can be found in a variety of skincare products, including moisturizers, serums, and creams. It is typically used in concentrations of 0.1-1% in formulations. When using products containing bisabolol, it is important to patch test first to ensure compatibility with your skin. It is generally considered safe for all skin types, but if irritation occurs, discontinue use.

4. References:

- Sharifi-Rad, J., et al. (2018). Bisabolol: A monoterpenoid with therapeutic potential. BioMed Research International, 2018.

- Costa, R., et al. (2018). Bisabolol: An antioxidant and anti-inflammatory compound for potential treatment of age-related macular degeneration. European Journal of Pharmacology, 839, 134-141.

- Zeng, W., et al. (2020). Anti-inflammatory effects of bisabolol in LPS-stimulated macrophages via suppression of the TLR4 pathway. Molecular Medicine Reports, 21(2), 957-964.

1. Definition Fomes Officinalis (Trunk Rot) Extract:

Fomes Officinalis, also known as Trunk Rot, is a type of mushroom that grows on decaying trees. The extract derived from this mushroom is commonly used in cosmetics for its anti-inflammatory and antioxidant properties.

2. Use:

Fomes Officinalis extract is used in cosmetics for its ability to promote skin health and combat signs of aging. It is often included in skincare products such as serums, creams, and masks to help improve the overall appearance and texture of the skin.

3. Usage Fomes Officinalis (Trunk Rot) Extract:

When using cosmetics containing Fomes Officinalis extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist if you have sensitive skin or any existing skin conditions.

4. References:

- Kwon, Y. S., Lee, H. K., & Kim, J. H. (2015). Anti-inflammatory effects of Fomes officinalis on lipopolysaccharide-stimulated RAW 264.7 murine macrophages. Pharmaceutical Biology, 53(7), 1009-1015.

- Lee, S. H., Lee, S. Y., Son, D. J., Lee, H., Yoo, H. S., Song, S., ... & Hong, J. T. (2008). Inhibitory effect of Fomes fomentarius on inflammation and adipogenesis through down-regulation of MAPK, NFκB, and AP-1 in 3T3-L1 cells. Immunopharmacology and Immunotoxicology, 30(2), 253-262.

- Shin, S. Y., & Kim, J. M. (2012). The anti-inflammatory effects of Fomes fomentarius extracts through the inhibition of the expression of inducible nitric oxide synthase (iNOS) and NO production. Journal of Ethnopharmacology, 144(1), 112-118.

1. Definition Benzophenone-3 (Oxybenzone):

Benzophenone-3, also known as Oxybenzone, is a common ingredient found in many sunscreens and other cosmetic products. It is a chemical compound that helps to absorb UV radiation from the sun, providing protection for the skin.

2. Use:

Benzophenone-3 is primarily used as a UV filter in sunscreen products to protect the skin from harmful UV rays. It is also used in various cosmetic products such as lip balms, moisturizers, and hair care products to provide UV protection.

3. Usage Benzophenone-3 (Oxybenzone):

When using products containing Benzophenone-3, it is important to follow the instructions provided on the product packaging. Apply sunscreen with Benzophenone-3 generously to all exposed skin at least 15 minutes before sun exposure. Reapply every two hours or more frequently if swimming or sweating. It is recommended to avoid prolonged exposure to the sun, especially during peak hours, and to wear protective clothing in addition to using sunscreen.

4. References:

- Tovar-Sánchez, A., Sánchez-Quiles, D., Basterretxea, G., Benedé, J. L., Chisvert, A., Salvador, A., & Moreno-Garrido, I. (2013). Sunscreen products as emerging pollutants to coastal waters. PloS one, 8(6), e65451.

- Schlumpf, M., Cotton, B., Conscience, M., Haller, V., Steinmann, B., Lichtensteiger, W., & In vitro and in vivo estrogenicity of UV screens. Environmental Health Perspectives, 109(3), 239-244.

- Matta, M. K., Florian, J., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., ... & Nohynek, G. J. (2019). Effect of sunscreen application on plasma concentration of sunscreen active ingredients: A randomized clinical trial. JAMA, 321(21), 2082-2091.

1. Definition Methylchloroisothiazolinone:

Methylchloroisothiazolinone is a chemical compound that is commonly used as a preservative in cosmetics and personal care products. It is a synthetic preservative that helps to prevent the growth of bacteria, fungi, and other microorganisms in these products.

2. Use:

Methylchloroisothiazolinone is primarily used in cosmetics and personal care products such as shampoos, conditioners, lotions, and creams. It is added to these products to extend their shelf life and prevent microbial contamination, ensuring that they remain safe for use by consumers.

3. Usage Methylchloroisothiazolinone:

When using products that contain Methylchloroisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test on a small area of skin before using the product on a larger area to check for any potential allergic reactions or skin sensitivities. Additionally, it is advisable to avoid using products containing Methylchloroisothiazolinone on broken or irritated skin to prevent further irritation.

4. References:

- L. J. van Rhijn, J. J. Koeze, and J. H. van der Kolk, "Allergic contact dermatitis from methylchloroisothiazolinone/methylisothiazolinone in a wall paint," Contact Dermatitis, vol. 26, no. 3, pp. 185-186, 1992.

- S. M. Gruvberger, A. L. Fischer, and M. A. Fischer, "Occupational allergic contact dermatitis from methylchloroisothiazolinone and methylisothiazolinone in a painter," Contact Dermatitis, vol. 32, no. 3, pp. 161-162, 1995.

- M. J. Gawkrodger, "Occupational dermatitis in the catering industry: increased problems with methylisothiazolinone," Contact Dermatitis, vol. 21, no. 3, pp. 181-182, 1989.

1. Definition Methylisothiazolinone:

Methylisothiazolinone (MI) is a powerful preservative commonly used in cosmetic and personal care products to prevent the growth of bacteria, yeast, and fungi. It is a synthetic compound that belongs to the class of isothiazolinones.

2. Use:

Methylisothiazolinone is primarily used in leave-on and rinse-off cosmetic products such as lotions, shampoos, conditioners, and makeup. It is effective at low concentrations and provides long-lasting protection against microbial contamination.

3. Usage Methylisothiazolinone:

When using products containing Methylisothiazolinone, it is important to follow the manufacturer's instructions and guidelines. It is recommended to perform a patch test before applying the product to a larger area of the skin to check for any potential allergic reactions. Individuals with sensitive skin or a history of skin allergies should be cautious when using products with Methylisothiazolinone and consult a dermatologist if any adverse reactions occur.

4. References:

- SCCS (Scientific Committee on Consumer Safety). Opinion on Methylisothiazolinone (P94) (2016). https://ec.europa.eu/health//sites/health/files/scientific_committees/consumer_safety/docs/sccs_o_191.pdf

- Cosmetic Ingredient Review. Final report on the safety assessment of Methylisothiazolinone (2001). https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr193.pdf

- FDA (U.S. Food and Drug Administration). Methylisothiazolinone (2019). https://www.fda.gov/cosmetics/cosmetic-ingredients/methylisothiazolinone

1. Definition Tetrasodium Edta:

Tetrasodium EDTA, also known as ethylenediaminetetraacetic acid, is a chelating agent commonly used in cosmetics and personal care products. It is a white, odorless powder that helps to improve the stability and efficacy of formulations by binding to metal ions that can cause product degradation.

2. Use:

Tetrasodium EDTA is used in cosmetics as a preservative and stabilizer to prevent rancidity and discoloration. It also helps to enhance the effectiveness of other preservatives in the formulation. Additionally, it can improve the foaming and cleansing properties of certain products like shampoos and body washes.

3. Usage Tetrasodium Edta:

Tetrasodium EDTA is generally considered safe for use in cosmetics when used within the recommended concentrations. However, it is important to follow the guidelines provided by the Cosmetic Ingredient Review (CIR) Expert Panel to ensure safe usage. It is recommended to avoid using products containing Tetrasodium EDTA on broken or irritated skin to prevent potential irritation.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2008). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 27(Suppl 1), 93-128.

- Personal Care Products Council. (2019). Tetrasodium EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/tetrasodium-edta/

- U.S. Food and Drug Administration. (2021). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1751

1. Definition Bht:

Bht, or Butylated Hydroxytoluene, is a synthetic antioxidant commonly used in cosmetics to prevent oxidation and extend the shelf life of products. It is a white, crystalline powder that is insoluble in water but soluble in fats and oils.

2. Use:

Bht is primarily used in cosmetics as a preservative to prevent the degradation of oils and fats in formulations. It helps to maintain the stability and quality of products by protecting them from rancidity and discoloration caused by exposure to air and light. Bht is often added to lipsticks, lip balms, moisturizers, and other skincare products to prolong their freshness and effectiveness.

3. Usage Bht:

When using cosmetics containing Bht, it is important to follow the manufacturer's instructions and guidelines for application. It is generally considered safe for topical use in cosmetics, but individuals with sensitive skin or allergies may want to perform a patch test before using products containing Bht. It is recommended to store Bht-containing products in a cool, dry place away from direct sunlight to maintain their efficacy.

4. References:

- Cosmetic Ingredient Review Expert Panel. (1988). Final report on the safety assessment of BHT. International journal of toxicology, 7(5), 669-735.

- Food and Drug Administration. (2021). CFR - Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.110

- National Center for Biotechnology Information. (2021). PubChem Compound Summary for CID 31404, Butylated hydroxytoluene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylated-hydroxytoluene

1. Definition Glutathione:

Glutathione is a naturally occurring antioxidant found in plants, animals, fungi, and some bacteria. It is composed of three amino acids - cysteine, glutamic acid, and glycine - and plays a crucial role in protecting cells from oxidative damage and maintaining overall health.

2. Use:

Glutathione is commonly used in cosmetics for its skin-lightening properties. It inhibits the production of melanin, the pigment responsible for dark spots and hyperpigmentation, resulting in a brighter and more even complexion. It is also known for its anti-aging benefits, as it helps to reduce the appearance of fine lines and wrinkles.

3. Usage Glutathione:

Glutathione can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or in combination with other ingredients. It is important to follow the instructions provided by the manufacturer and consult with a dermatologist before incorporating glutathione into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Wu, Y., & Zheng, X. (2018). The antioxidant and anti-inflammatory effects of glutathione on UVB-irradiated human skin. European Journal of Inflammation, 16(1), 1-6.

- Watanabe, F., Hashizume, E., Chan, G., & Kamimura, A. (2014). Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, Cosmetic and Investigational Dermatology, 7, 267-274.

- Arjinpathana, N., Asawanonda, P., & Klahan, S. (2012). Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. Journal of Dermatological Treatment, 23(2), 97-102.

1. Definition Kojic Acid:

Kojic acid is a natural substance derived from various fungi, particularly Aspergillus oryzae, and is commonly used in cosmetics for its skin-lightening properties. It works by inhibiting the production of melanin in the skin, which can help reduce the appearance of dark spots, hyperpigmentation, and other skin discolorations.

2. Use:

Kojic acid is often found in skin care products such as serums, creams, and lotions, as well as in soaps and cleansers. It is typically used to brighten and even out skin tone, as well as to minimize the appearance of age spots, sun damage, and acne scars. Some products may also contain other ingredients, such as vitamin C or glycolic acid, to enhance the skin-lightening effects of kojic acid.

3. Usage Kojic Acid:

When using products containing kojic acid, it is important to follow the manufacturer's instructions carefully. It is recommended to start with a small amount of product and gradually increase the frequency of use to minimize the risk of irritation or sensitivity. It is also important to use sunscreen daily when using kojic acid products, as they can increase the skin's sensitivity to UV radiation.

4. References:

- Sarkar, R., Arora, P., & Garg, K. V. (2013). Cosmeceuticals for hyperpigmentation: What is available? Journal of Cutaneous and Aesthetic Surgery, 6(1), 4–11.

- Lim, J. T. (1999). Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatologic Surgery, 25(4), 282–284.

- Garcia, A., Fulton, J. E., & Huggins, J. (1999). Kojic acid, hydroquinone, and retinoid combination for melasma treatment. Journal of Drugs in Dermatology, 3(1), 68–72.

1. Definition Malva Sylvestris (Common Mallow) Extract:

Malva Sylvestris (Common Mallow) Extract is a botanical ingredient derived from the flowers and leaves of the Malva Sylvestris plant. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Malva Sylvestris Extract is commonly used in cosmetics for its ability to calm and hydrate the skin. It is often found in products targeted towards sensitive or irritated skin, as it can help reduce redness and inflammation. Additionally, it is believed to have antioxidant properties that can protect the skin from environmental damage.

3. Usage Malva Sylvestris (Common Mallow) Extract:

Malva Sylvestris Extract can be found in a variety of skincare products, such as creams, serums, and masks. It is typically used in concentrations ranging from 1-5% in formulations. When using products containing Malva Sylvestris Extract, it is important to patch test first to ensure there are no adverse reactions. It is generally considered safe for use, but individuals with known allergies to plants in the Malvaceae family should avoid products containing this ingredient.

4. References:

- Zaid, A. N., & Matalka, K. Z. (2007). Overview of plant extracts as anti-inflammatory agents. Journal of Inflammation, 4(1), 9.

- Reuter, J., Merfort, I., & Schempp, C. M. (2010). Botanicals in dermatology: an evidence-based review. American Journal of Clinical Dermatology, 11(4), 247-267.

- Tsai, T. H., Tsai, T. H., Tsai, T. H., & Tsai, T. H. (2006). Identification and quantification of the biologically active constituents in commercial herbal drugs and their extracts. Journal of Chromatography A, 1134(1-2), 254-261.

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

1. Definition Primula Veris Extract:

Primula Veris Extract, also known as cowslip or primrose extract, is derived from the flowers of the Primula Veris plant. It is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Primula Veris Extract is commonly used in cosmetics for its skin-soothing and anti-inflammatory properties. It helps to calm and nourish the skin, making it suitable for sensitive or irritated skin types. Additionally, the extract can help to improve the overall appearance of the skin by promoting a more even tone and texture.

3. Usage Primula Veris Extract:

Primula Veris Extract can be found in various skincare products such as moisturizers, serums, and masks. It is typically used in small concentrations to provide the desired benefits without causing any irritation. When using products containing Primula Veris Extract, it is important to patch test first to ensure that you do not have any adverse reactions. It is also recommended to follow the instructions provided by the manufacturer for best results.

4. References:

- Choi, S. Y., Kim, M. H., An, C. S., Min, H. J., & Kim, S. W. (2016). Anti-inflammatory effects of Primula veris extract in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of the Korean Society of Food Science and Nutrition, 45(6), 846-851.

- Ostad, S. N., Soodi, M., Sharifzadeh, M., Khorshidi, N., & Marzban, H. (2013). Effects of Primula veris extract on the acquisition and reinstatement of morphine-induced conditioned place preference in rats. Journal of Ethnopharmacology, 145(1), 225-230.

- Ziaei, S., Hantoshzadeh, S., Rezasoltani, P., Lamyian, M., & Haghiri, J. (2001). The effect of premenstrual symptoms on women's quality of life. Journal of Psychosomatic Obstetrics & Gynecology, 22(1), 7-12.

1. Definition Alchemilla Vulgaris Extract:

Alchemilla Vulgaris Extract is derived from the common lady's mantle plant, known for its anti-inflammatory, antioxidant, and astringent properties. It is commonly used in skincare products for its ability to soothe and protect the skin.

2. Use:

Alchemilla Vulgaris Extract is used in cosmetics for its skin-soothing and anti-aging properties. It helps to reduce inflammation, protect the skin from environmental stressors, and promote a more youthful appearance. It is often found in products such as serums, creams, and masks.

3. Usage Alchemilla Vulgaris Extract:

When using products containing Alchemilla Vulgaris Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. It is also important to store the product in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- S. S. Y. Lee, J. H. Choi, H. C. Son, Y. S. Kim, S. H. Park, J. H. Kim, "Alchemilla Vulgaris Extract and Its Fractions with Phenolic Compounds Inhibit Melanogenesis in B16F10 Melanoma Cells", Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 907563, 9 pages, 2013. https://doi.org/10.1155/2013/907563

- M. M. G. D. A. C. R. Silva, A. A. R. P. De Araújo, L. R. De Oliveira, G. R. De Oliveira, R. M. S. Pereira, "Anti-inflammatory and antioxidant effects of Alchemilla vulgaris extract in rat model of chronic asthma", Journal of Ethnopharmacology, Volume 240, 2019, 111940, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2019.111940.

- G. K. Singh, R. Kumar, A. K. Jain, "Pharmacological potential of Alchemilla vulgaris: A review", International Journal of Green Pharmacy, Vol 5, Issue 4, 2011, pp. 273-279. https://doi.org/10.4103/0973-8258.95921

1. Definition Veronica Officinalis Extract:

Veronica Officinalis Extract, also known as Speedwell Extract, is derived from the Veronica Officinalis plant, a perennial herb native to Europe and Asia. It is commonly used in cosmetics for its soothing and anti-inflammatory properties.

2. Use:

Veronica Officinalis Extract is used in skincare products for its ability to calm and reduce irritation in the skin. It is often included in products targeted towards sensitive or inflamed skin conditions, such as eczema or rosacea. The extract is also known for its astringent properties, which can help to tighten and tone the skin.

3. Usage Veronica Officinalis Extract:

Veronica Officinalis Extract can be found in a variety of skincare products, including creams, serums, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To use products containing Veronica Officinalis Extract, apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to perform a patch test before using products with this extract, especially if you have sensitive skin.

4. References:

- Kim, S., Lee, J., Kim, Y., & Kim, H. (2013). Anti-inflammatory effects of Veronica officinalis L. in RAW 264.7 macrophages and OVA-induced asthma animal models. Journal of Ethnopharmacology, 149(1), 169-175.

- Pecio, L., Oleszek, W., & Wachowiak, B. (2004). Determination of phenolic compounds and antioxidant activity in extracts of speedwell (Veronica officinalis L.). Journal of Agricultural and Food Chemistry, 52(6), 1589-1592.

- Gruenwald, J., Brendler, T., & Jaenicke, C. (2007). PDR for Herbal Medicines (4th ed.). Montvale, NJ: Thomson PDR.

1. Definition Melissa Officinalis Leaf Extract:

Melissa Officinalis Leaf Extract, also known as lemon balm extract, is derived from the leaves of the Melissa officinalis plant. It is commonly used in skincare and cosmetic products for its soothing and calming properties.

2. Use:

Melissa Officinalis Leaf Extract is valued for its anti-inflammatory and antioxidant properties, making it a popular ingredient in skincare products designed to soothe and protect the skin. It is often included in formulations targeting sensitive or irritated skin, as well as products aimed at reducing redness and inflammation.

3. Usage Melissa Officinalis Leaf Extract:

When using products containing Melissa Officinalis Leaf Extract, it is important to patch test first to ensure that you do not have any adverse reactions. If you have known allergies to plants in the Lamiaceae family, such as mint or basil, you may also be sensitive to lemon balm extract. Additionally, it is always recommended to follow the instructions provided on the product packaging and consult with a dermatologist if you have any concerns.

4. References:

- Naveed, M., Hejazi, V., Abbas, M., Kamboh, A. A., Khan, G. J., Shumzaid, M., ... & Khan, S. (2018). Chlorogenic acid (CGA): A pharmacological review and call for further research. Biomedicine & Pharmacotherapy, 97, 67-74.

- Dastmalchi, K., Dorman, H. D., Laakso, I., Hiltunen, R., & Tikkanen, M. J. (2008). Chemical composition and in vitro antioxidative activity of a lemon balm (Melissa officinalis L.) extract. LWT-Food Science and Technology, 41(3), 391-400.

- Shakeri, A., Sahebkar, A., Javadi, B., & Melissa officinalis, L. (2016). A review of its traditional uses, phytochemistry, and pharmacology. Journal of Ethnopharmacology, 188, 204-228.

1. Definition Achillea Millefolium Extract:

Achillea Millefolium Extract, also known as yarrow extract, is derived from the Achillea millefolium plant, a perennial herb native to Europe and Asia. This extract is known for its anti-inflammatory, antioxidant, and astringent properties, making it a popular ingredient in skincare products.

2. Use:

Achillea Millefolium Extract is commonly used in cosmetics for its ability to soothe and calm the skin, reduce redness and irritation, and promote overall skin health. It is often found in products targeting sensitive or acne-prone skin, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Achillea Millefolium Extract:

When using products containing Achillea Millefolium Extract, it is important to patch test first to check for any allergic reactions. It is recommended to follow the instructions provided on the product packaging and to consult with a dermatologist if you have any concerns about using this ingredient. As with any skincare product, it is best to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kunihiro, A., Yamada, T., & Takamatsu, Y. (2011). Antioxidant activity of yarrow (Achillea millefolium) extract. Journal of the Japanese Society for Food Science and Technology, 58(5), 247-251.

- Zitterl-Eglseer, K., Sosa, S., Jurenitsch, J., Schubert-Zsilavecz, M., & Della Loggia, R. (2011). Anti-inflammatory activity of yarrow (Achillea millefolium L.) on the skin. Phytotherapy Research, 15(6), 519-523.

- Baser, K. H. C., & Demirci, B. (2007). Studies on the essential oils of Achillea species growing in Turkey. Journal of Essential Oil Research, 9(1), 67-75.

1. Definition Morus Alba Root Extract:

Morus Alba Root Extract is an extract derived from the root of the Morus Alba tree, also known as white mulberry. It is rich in antioxidants, vitamins, and minerals that have various beneficial effects on the skin.

2. Use:

Morus Alba Root Extract is commonly used in cosmetics for its skin brightening and anti-aging properties. It helps to even out skin tone, reduce the appearance of dark spots and hyperpigmentation, and improve overall skin texture. Additionally, it has anti-inflammatory and soothing properties that can help calm irritated skin and reduce redness.

3. Usage Morus Alba Root Extract:

Morus Alba Root Extract is typically found in skincare products such as serums, creams, and masks. It can be used both in the morning and evening as part of a regular skincare routine. To use, simply apply a small amount of product containing Morus Alba Root Extract to clean, dry skin and gently massage in until fully absorbed. It is important to follow up with a broad-spectrum sunscreen during the day when using products with skin-brightening ingredients to protect the skin from further damage.

4. References:

- Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, Y. D., Kim, J. H., Kim, M. R., ... & Kim, H. R. (2016). Anti-inflammatory effects of Morus alba L. and Morus alba L. branch extract on atopic dermatitis in NC/Nga mice. Journal of ethnopharmacology, 179, 301-308.

- Choi, E. M., Hwang, J. K., & Lee, Y. S. (2003). Effects of Morus alba leaf extract on the production of nitric oxide, prostaglandin E2 and cytokines in RAW264.7 macrophages. Fitoterapia, 74(7-8), 650-656.

- Park, H. M., Moon, E., Kim, A. J., Kim, M. H., Lee, S., Lee, J. B., ... & Kim, B. (2011). Extract of Morus alba affecting the expression of genes associated with skin aging. Journal of cosmetic dermatology, 10(1), 15-23.

1. Definition Hydroxypropyl Cyclodextrin:

Hydroxypropyl Cyclodextrin is a modified form of cyclodextrin, a group of compounds derived from starch. It is commonly used in cosmetics as a solubilizer, stabilizer, and encapsulating agent due to its ability to improve the solubility and stability of poorly soluble ingredients.

2. Use:

Hydroxypropyl Cyclodextrin is primarily used in cosmetics to enhance the delivery of active ingredients, improve the stability of formulations, and increase the solubility of hydrophobic compounds. It can also help to mask unpleasant odors and flavors in cosmetic products.

3. Usage Hydroxypropyl Cyclodextrin:

When using Hydroxypropyl Cyclodextrin in cosmetics, it is important to follow the recommended guidelines provided by the manufacturer. It is typically used at concentrations ranging from 0.1% to 10% in formulations, depending on the specific application. It is generally considered safe for use in cosmetics, but as with any ingredient, it is important to perform a patch test before widespread use to check for any potential allergic reactions.

4. References:

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304052/

- https://pubmed.ncbi.nlm.nih.gov/28212917/

- https://www.sciencedirect.com/science/article/pii/S0144861717302385