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| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 2 4 | A | (Fragrance, Preservative) | |
| 1 | - | Good for dry skin Anti Aging | |
| 2 | A | (Deodorant, Skin Conditioning) | |
| 1 | A | (Solvent, Masking, Perfuming, Skin Conditioning, Emollient) | |
| 4 5 | - | (Solvent, Perfuming, Deodorant) | Allergen Fragrance-free |
| 3 | - | (Masking, Deodorant, Fragrance) | Allergen Fragrance-free |
| 1 | A | (Solvent, Masking, Fragrance, Humectant, Skin Conditioning, Viscosity Controlling, Viscosity decreasing agents) | Good for dry skin |
| 1 | - | (Skin Conditioning, Emollient) | |
| 1 | A | (Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Viscosity Increasingagent - Aqueous) | Cleansing |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 1 | A | (Humectant, Skin Conditioning) | Good for dry skin Promotes Wound Healing |
| 3 | - | (Masking, Fragrance) | Allergen Fragrance-free |
| 1 | B | (Perfuming, Fragrance, Antioxidant, Skin-Conditioning Agent -Miscellaneous, Skin-Conditioning Agent - Occlusive, Antimicrobial Agent) | |
| 1 | A | (Hair Conditioning, Skin Conditioning, Emollient, Refatting) | |
| 1 | A | Fungal Acne Trigger | |
| 1 | B | (Skin Conditioning, Emollient) | |
| 1 | A | (Emulsifying, Surfactant) | Fungal Acne Trigger Cleansing |
| 1 2 | - | (Skin Conditioning, Emollient) | Fungal Acne Trigger |
| 1 | B | (Hair Conditioning) | Fungal Acne Trigger |
| 1 | A | (Fragrance, Emulsifying, Surfactant) | Bad for oily skin Fungal Acne Trigger Cleansing |
| 1 | B | (Masking, Fragrance, Skin Conditioning, Emollient) | Fungal Acne Trigger |
| 1 | - | (Viscosity Increasing Agent, Emulsion Stabilising, Opacifying, Anticaking Agent, Suspending Agent - Nonsurfactant) | |
| 1 | A | (Surfactant, Emulsifying) | Fungal Acne Trigger Cleansing |
| 2 5 | - | | |
| 1 | - | (Skin Protecting) | Moisturizing |
| EWG | CIR | Ingredient Name & Cosmetic Function | Notes |
|---|---|---|---|
| 1 | - | (Solvent) | |
| 1 2 | A | (Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant ) | Good for dry skin Moisturizing |
| 2 4 | A | (Fragrance, Preservative) | |
| 1 | - | Good for dry skin Anti Aging | |
| 1 3 | A | (Skin Protecting, Skin Conditioning, Emollient, Antifoaming Agent) | Moisturizing |
| 1 | A | Bad for oily skin Fungal Acne Trigger | |
| 1 | A | (Solvent, Masking, Perfuming, Skin Conditioning, Emollient) | |
| 1 | A | (Hair Conditioning, Skin Conditioning, Antistatic Agent) | Good for dry skin Promotes Wound Healing |
| 1 | A | (Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Binding Agent, Binding, Surfactant - Emulsifying Agent, Gel Forming) | |
| 1 3 | - | | |
| 1 | - | (Skin Conditioning, Emollient) | |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant) | Cleansing |
| 1 | A | (Masking, Fragrance, Emulsion Stabilising, Emulsifying, Sufactant, Refatting) | Bad for oily skin Fungal Acne Trigger Cleansing |
| 1 | - | (Skin Conditioning, Emollient, Surfactant, Fragrance, Emulsifying) | Fungal Acne Trigger Cleansing |
| 1 2 | - | (Skin Conditioning, Emollient, Antistatic Agent, Emulsifying, Surfactant) | Cleansing |
| 1 | A | (Skin Conditioning) | Good for dry skin Bad for oily skin |
| 1 | A | (Masking, Fragrance, Opacifying, Emollient, Viscosity Controlling, Viscosity Increasing Agent, Emulsion Stabilising, Emulsifying, Foam Boosting, Surfactant, Refatting) | Cleansing |
| 1 | A | (Skin Protecting, Skin Conditioning, Soothing) | Good for sensitive skin Good for oily skin Moisturizing |
| 3 | - | | |
| 1 | A | (Humectant, Skin Conditioning, Antistatic Agent, Viscosity Increasing Agent, Moisturising) | Promotes Wound Healing Moisturizing |
| 1 | A | (Skin Conditioning, Humectant, Antistatic Agent, Hair Conditioning) | |
| 1 | A | (Skin Conditioning, Emollient) | Good for dry skin Bad for oily skin Fungal Acne Trigger |
| 1 4 | B | (pH adjusting agent, pH adjusting agent, Exfoliant) | Anti Aging Bad for sensitive skin Good for oily skin |
| 1 2 | - | (Masking, Fragrance, Humectant, Skin Protecting, Uv Absorber, Skin Conditioning, Antioxidant, Emollient, Antimicrobial, Astringent, Tonic, Skin-Conditioning Agent -Miscellaneous) | Moisturizing |
| 1 | - | (Skin Conditioning) | |
Water
1. Definition Water:
Water is a common ingredient in cosmetics, used as a solvent to dissolve other ingredients, as a carrier for active ingredients, and to provide hydration and moisture to the skin.2. Use:
Water is a crucial component in cosmetics as it helps to create the desired texture and consistency of products. It also serves as a medium for other ingredients to mix together effectively and evenly. Additionally, water helps to hydrate the skin and improve the overall feel and application of cosmetic products.3. Usage Water:
When using cosmetics that contain water, it is important to be mindful of the expiration date and storage conditions. Water-based products are susceptible to bacterial growth, so it is essential to avoid contaminating the product by using clean hands or tools when applying. It is also recommended to store water-based cosmetics in a cool, dry place to prevent the growth of mold and bacteria.4. References:
- Draelos, Z. D. (2010). Cosmetic dermatology: products and procedures. John Wiley & Sons.
- Winter, R. (2009). A consumer's dictionary of cosmetic ingredients: complete information about the harmful and desirable ingredients found in cosmetics and cosmeceuticals. Crown.
- Begoun, P. (2003). Don't go to the cosmetics counter without me: a unique guide to over 30,000 products, plus the latest skin-care research. Beginning Press.
Glycerin
1. Definition Glycerin:
Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.
2. Use:
Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.
3. Usage Glycerin:
When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.
4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.
Phenoxyethanol
1. Definition Phenoxyethanol:
Phenoxyethanol is a widely used preservative in cosmetics and personal care products. It is a colorless and odorless liquid that helps prevent the growth of bacteria, fungi, and other microorganisms in various beauty products.2. Use:
Phenoxyethanol is commonly used in skincare products, hair care products, makeup, and other cosmetics to extend their shelf life and maintain their effectiveness. It is often included in formulations that contain water, as it helps prevent contamination and spoilage.3. Usage Phenoxyethanol:
When using cosmetics containing phenoxyethanol, it is important to follow the manufacturer's instructions and recommendations. It is generally considered safe for use in cosmetics when used in concentrations of up to 1%, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products with phenoxyethanol, especially if you have sensitive skin.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.
- Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... & Andersen, F. A. (2016). Safety assessment of phenoxyethanol as used in cosmetics. International Journal of Toxicology, 35(4), 386-419.
Tocopherol
1. Definition Tocopherol:
Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.2. Use:
Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.3. Usage Tocopherol:
Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.
- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.
Ethylhexylglycerin
1. Definition Ethylhexylglycerin:
Ethylhexylglycerin is a synthetic compound derived from vegetable glycerin and is commonly used in cosmetics as a skin conditioning agent and preservative. It is a clear, colorless liquid with a faint odor.2. Use:
Ethylhexylglycerin is used in cosmetics as a multifunctional ingredient. It acts as a skin conditioning agent, moisturizer, and preservative. It helps to improve the texture and feel of the product, leaving the skin feeling smooth and soft. Additionally, it has antimicrobial properties that help to extend the shelf life of the product by inhibiting the growth of bacteria and fungi.3. Usage Ethylhexylglycerin:
Ethylhexylglycerin is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. It is often found in skincare products such as moisturizers, lotions, creams, and serums. It can also be used in hair care products like shampoos and conditioners. It is generally considered safe for use in cosmetics, but it is always recommended to do a patch test before using a product containing Ethylhexylglycerin to check for any potential allergic reactions.4. References:
- "Ethylhexylglycerin." Cosmetics Info, www.cosmeticsinfo.org/ingredient/ethylhexylglycerin.
- "Safety Assessment of Ethylhexylglycerin as Used in Cosmetics." Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/ethylhexylg012017rep.pdf.
- "Ethylhexylglycerin." Truth In Aging, www.truthinaging.com/ingredients/ethylhexylglycerin.
Caprylic/ Capric Triglyceride
1. Definition Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.2. Use:
Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.3. Usage Caprylic/ Capric Triglyceride:
Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.4. References:
- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.
- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.
- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.
Limonene
1. Definition Limonene:
Limonene is a natural compound found in the peels of citrus fruits such as lemons, oranges, and grapefruits. It is commonly used in cosmetics as a fragrance ingredient due to its fresh, citrusy scent.2. Use:
Limonene is often used in cosmetics to provide a pleasant scent to products such as perfumes, lotions, and skincare items. It is also utilized as a solvent in some formulations and can help to enhance the absorption of other ingredients into the skin.3. Usage Limonene:
When using products containing limonene, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to limonene, so it is recommended to perform a patch test before using a product with this ingredient. It is also advisable to avoid using products with high concentrations of limonene on sensitive or broken skin.4. References:
- Burdock, G. A. (2010). Fenaroli's handbook of flavor ingredients. CRC Press.
- Reifenrath, W. G., & Chirico, S. (2012). Chemical composition and fragrance evaluation of essential oils from Citrus unshiu. Journal of essential oil research, 24(1), 61-69.
- Jäger, W., Buchbauer, G., Jirovetz, L., Fritzer, M., & Woidich, A. (1992). Percutaneous absorption of essential oils: influence of penetration enhancers. Journal of pharmaceutical sciences, 81(3), 254-258.
Linalool
1. Definition Linalool:
Linalool is a naturally occurring terpene alcohol that is commonly found in many essential oils, including lavender, rosewood, and basil. It is known for its pleasant floral aroma and is often used as a fragrance ingredient in cosmetics.2. Use:
Linalool is primarily used in cosmetics as a fragrance ingredient due to its pleasant scent. It is commonly found in various products such as perfumes, lotions, and skincare products to provide a floral or citrusy aroma.3. Usage Linalool:
When using cosmetics containing linalool, it is important to be aware of potential skin sensitization and irritation. Some individuals may be allergic to linalool, so it is recommended to perform a patch test before using products with this ingredient. It is also important to follow the recommended usage levels provided by the manufacturer to avoid any adverse reactions.4. References:
- Andersen, F. A. (2008). Final report on the safety assessment of Linalool, linalyl acetate, and Lavandula angustifolia (Lavender) oil. International Journal of Toxicology, 27(1), 1-28.
- Opdyke, D. L. (1976). Monographs on fragrance raw materials. Food and Cosmetics Toxicology, 14(5), 479-480.
- Reifenrath, W. G., & Van Beek, T. A. (2013). Linalool and linalool rich essential oils. In Natural Products (pp. 1541-1587). Springer, Berlin, Heidelberg.
Butylene Glycol
1. Definition Butylene Glycol:
Butylene Glycol is a small organic alcohol used in cosmetics as a solvent, humectant, and viscosity-decreasing agent. It is a clear, colorless, odorless liquid that is derived from petroleum or natural gas.2. Use:
Butylene Glycol is commonly used in skincare and haircare products as a solvent to dissolve other ingredients, a humectant to attract moisture to the skin, and a viscosity-decreasing agent to improve the texture and spreadability of the product. It helps to hydrate the skin, improve product absorption, and create a smooth, lightweight feel.3. Usage Butylene Glycol:
Butylene Glycol is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is important to patch test products containing Butylene Glycol before use, especially if you have sensitive skin. Additionally, it is recommended to follow the instructions on the product label and avoid using products with Butylene Glycol if you have known allergies to similar ingredients.4. References:
- Cosmetic Ingredient Review Expert Panel. (2001). Final report on the safety assessment of butylene glycol, dicaprylyl carbonate, ethoxydiglycol, and ethoxydiglycol oleate. International Journal of Toxicology, 20(Suppl 4), 61-75.
- National Center for Biotechnology Information. PubChem Compound Summary for CID 24856, Butylene Glycol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Butylene-glycol
- Personal Care Products Council. (2017). Butylene Glycol. Retrieved from https://www.cosmeticsinfo.org/ingredient/butylene-glycol
Helianthus Annuus (Sunflower) Oil
1. Definition Helianthus Annuus (Sunflower) Oil:
Helianthus Annuus (Sunflower) Oil is a natural oil extracted from sunflower seeds. It is rich in vitamins, antioxidants, and essential fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Sunflower oil is commonly used in cosmetics for its moisturizing properties. It helps to hydrate and nourish the skin, leaving it soft and smooth. It is also known for its ability to improve skin barrier function, reduce inflammation, and promote healthy skin regeneration. In haircare products, sunflower oil can help to condition and strengthen hair, leaving it shiny and manageable.3. Usage Helianthus Annuus (Sunflower) Oil:
Sunflower oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to creams, lotions, and serums to enhance their hydrating properties. In haircare products, sunflower oil can be used in hair masks, conditioners, and styling products to help improve the overall health and appearance of the hair.Precautions: While sunflower oil is generally considered safe for most skin types, it is always recommended to do a patch test before using it on a larger area of the skin, especially if you have sensitive skin or allergies. If any irritation occurs, discontinue use immediately. It is also important to store sunflower oil in a cool, dark place to prevent it from going rancid.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Meier, L., & Stange, R. (2019). Sunflower oil in skincare: a comprehensive review of its benefits. Cosmetics, 6(1), 16.
- Suleman, T., & Van Vuuren, S. (2015). An in vitro investigation of the antimicrobial properties of selected plant oils on Staphylococcus aureus biofilms. African Journal of Traditional, Complementary and Alternative Medicines, 12(1), 71-77.
Cetearyl Alcohol
1. Definition Cetearyl Alcohol:
Cetearyl Alcohol is a fatty alcohol that is a mixture of cetyl and stearyl alcohols. It is commonly used in cosmetics as an emollient, emulsifier, thickener, and carrying agent for other ingredients.2. Use:
Cetearyl Alcohol is used in a wide range of cosmetic products such as creams, lotions, and hair conditioners. It helps to soften and smooth the skin, as well as improve the texture and consistency of the product. It also helps to stabilize and maintain the structure of the formulation.3. Usage Cetearyl Alcohol:
When using products containing Cetearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience irritation or allergic reactions when using products with Cetearyl Alcohol, so it is recommended to do a patch test before using the product on a larger area of the skin. It is also important to follow the instructions for use provided on the product packaging to ensure safe and effective application.4. References:
- "Cetearyl Alcohol" by Paula Begoun, Cosmetics Cop, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetearyl-alcohol.html
- "Cetearyl Alcohol in Cosmetics: Safe or Harmful?" by Dr. Anvita Arora, Dermatologist, https://www.dranvitaarora.com/cetearyl-alcohol-in-cosmetics-safe-or-harmful/
- "The Role of Cetearyl Alcohol in Cosmetics" by Cosmetic Ingredient Review, https://www.cir-safety.org/sites/default/files/cetearylcir.pdf
Cetyl Alcohol
1. Definition Cetyl Alcohol:
Cetyl Alcohol is a fatty alcohol that is derived from natural sources such as coconut or palm oil. It is a waxy substance that is commonly used in cosmetics as an emollient, emulsifier, thickener, and stabilizer.2. Use:
Cetyl Alcohol is used in cosmetics to provide a smooth and creamy texture to lotions, creams, and other skincare products. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers and body lotions. Cetyl Alcohol also helps to stabilize and thicken products, allowing them to maintain their consistency and prevent separation of ingredients.3. Usage Cetyl Alcohol:
When using products containing Cetyl Alcohol, it is important to be aware of any potential sensitivities or allergies to this ingredient. While Cetyl Alcohol is generally considered safe for use in cosmetics, some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products with Cetyl Alcohol, especially if you have sensitive skin. Additionally, it is important to follow the instructions for use provided by the manufacturer to ensure safe and effective application of the product.4. References:
- "Cetyl Alcohol" by Cosmetics Info (https://cosmeticsinfo.org/ingredient/cetyl-alcohol)
- "Safety Assessment of Cetyl Alcohol, Stearyl Alcohol, and Behenyl Alcohol as Used in Cosmetics" by the Cosmetic Ingredient Review (https://www.cir-safety.org/sites/default/files/final_report_alcohols.pdf)
- "Cetyl Alcohol" by Paula's Choice Skincare Ingredient Dictionary (https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-alcohol.html)
Sodium Hyaluronate
1. Definition Sodium Hyaluronate:
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.2. Use:
Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.3. Usage Sodium Hyaluronate:
When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.
4. References:
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
Hexyl Cinnamal
1. Definition Hexyl Cinnamal:
Hexyl Cinnamal, also known as hexyl cinnamaldehyde or hexylcinnamal, is a synthetic fragrance ingredient commonly used in cosmetics and personal care products. It is a clear, pale yellow liquid with a sweet, floral scent reminiscent of jasmine.2. Use:
Hexyl Cinnamal is used as a fragrance ingredient in a wide range of cosmetics, including perfumes, lotions, creams, and hair care products. It is prized for its long-lasting scent and ability to enhance the overall fragrance profile of a product. Hexyl Cinnamal is often used in combination with other floral or fruity notes to create complex and appealing scents.3. Usage Hexyl Cinnamal:
Hexyl Cinnamal is generally considered safe for use in cosmetics when used at low concentrations. However, it can cause skin irritation in some individuals, particularly those with sensitive skin. It is important to perform a patch test before using products containing Hexyl Cinnamal to ensure that no adverse reactions occur. Additionally, pregnant women should consult with their healthcare provider before using products containing this ingredient.4. References:
- "Hexyl Cinnamal" in Cosmeticsinfo.org, https://cosmeticsinfo.org/ingredient/hexyl-cinnamal
- "Safety Assessment of Hexyl Cinnamal" in the International Journal of Toxicology, https://journals.sagepub.com/doi/10.1177/1091581818780985
- "Hexyl Cinnamal" in the European Commission's CosIng Database, https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=30132
Rosmarinus Officinalis (Rosemary) Leaf Extract
1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:
Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.2. Use:
Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:
Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.4. References:
- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.
- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.
- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.
Squalane
1. Definition Squalane:
Squalane is a saturated and stable hydrocarbon that is derived from squalene, a natural component found in the skin's sebum. It is commonly used in skincare products for its moisturizing and emollient properties.2. Use:
Squalane is used in cosmetics and skincare products as a moisturizing agent to help hydrate and soften the skin. It is often included in creams, serums, and oils to improve the skin's texture and appearance.3. Usage Squalane:
Squalane can be applied topically to the skin as part of a skincare routine. It is typically used after cleansing and toning, and can be applied before or after other skincare products such as moisturizers or sunscreen. Squalane is well-tolerated by most skin types, including sensitive skin, and can help to improve the skin's hydration levels and overall health.Precautions: While squalane is generally considered safe for topical use, it is always recommended to do a patch test before using any new skincare product to check for any potential allergies or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating squalane into their skincare routine.
4. References:
- Baumann, L. (2005). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill.
- Draelos, Z. D. (2015). Cosmeceuticals. Philadelphia: Saunders.
- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327-348.
Prunus Armeniaca (Apricot) Kernel Oil
1. Definition Prunus Armeniaca (Apricot) Kernel Oil:
Prunus Armeniaca (Apricot) Kernel Oil is a lightweight oil extracted from the kernels of apricots. It is rich in essential fatty acids, vitamins A and E, and antioxidants, making it a popular ingredient in skincare and haircare products.2. Use:
Apricot Kernel Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate and soften the skin, leaving it smooth and supple. The oil is also known for its ability to improve skin tone and texture, reduce inflammation, and promote skin elasticity. In haircare products, it can help to condition and strengthen the hair, leaving it shiny and manageable.3. Usage Prunus Armeniaca (Apricot) Kernel Oil:
Apricot Kernel Oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, serums, and balms to enhance their hydrating properties. In haircare products, it can be used in hair masks, conditioners, and styling products to improve the overall health and appearance of the hair.Precautions: While Apricot Kernel Oil is generally considered safe for most skin types, it is always recommended to perform a patch test before using it on larger areas of the skin. Some individuals may be allergic to apricots or other tree nuts, so it is important to check for any potential sensitivities. Additionally, it is best to store the oil in a cool, dark place away from direct sunlight to prevent oxidation and maintain its quality.
4. References:
- Lin, T. K., Zhong, L., & Santiago, J. L. (2017). Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences, 19(1), 70.
- Ahmad, Z. (2010). The uses and properties of almond oil. Complementary Therapies in Clinical Practice, 16(1), 10-12.
- Ranzato, E., Martinotti, S., & Burlando, B. (2011). Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology, 134(2), 443-449.
Coco Caprylate/ Caprate
1. Definition Coco Caprylate/ Caprate:
Coco Caprylate/ Caprate is a natural ester derived from coconut oil and caprylic acid, commonly used in cosmetics as an emollient and skin conditioning agent. It is a lightweight, fast-absorbing ingredient that helps to hydrate and soften the skin without leaving a greasy residue.2. Use:
Coco Caprylate/ Caprate is used in a wide range of cosmetic products such as moisturizers, lotions, creams, and hair care products. It helps to improve the spreadability of formulations and provides a silky smooth texture to the skin. Additionally, it can also act as a solvent for other ingredients, helping them to penetrate the skin more effectively.3. Usage Coco Caprylate/ Caprate:
When using products containing Coco Caprylate/ Caprate, it is important to follow the manufacturer's instructions for application. It is generally considered safe for use on the skin, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas. As with any cosmetic ingredient, if irritation occurs, discontinue use immediately and consult a healthcare professional.4. References:
- "Coco-Caprylate/Caprate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/coco-caprylatecaprate
- "Coco-Caprylate" by Truth In Aging, https://www.truthinaging.com/ingredients/coco-caprylate
- "Coco-Caprylate" by Skin Deep, https://www.ewg.org/skindeep/ingredients/706751-COCO-CAPRYLATE/
Sorbitan Olivate
1. Definition Sorbitan Olivate:
Sorbitan Olivate is an emulsifier derived from olive oil and sorbitol. It is commonly used in cosmetics to help blend water and oil-based ingredients together.2. Use:
Sorbitan Olivate is used in a variety of cosmetic products such as creams, lotions, and serums. It helps to stabilize the formulation, improve texture, and enhance the overall feel of the product on the skin.3. Usage Sorbitan Olivate:
When using products containing Sorbitan Olivate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, it is recommended to discontinue use if any irritation or adverse reactions occur.4. References:
- Rizzi, V., L. Cavaletti, L. Battaglia, and C. Banchelli. "Sorbitan Olivate: A Natural Alternative to Synthetic Emulsifiers." International Journal of Cosmetic Science 34, no. 1 (2012): 73-81.
- Lopes, L. B., and S. L. Bentley. "Sorbitan Olivate: A Natural Multifunctional Biomimetic Emulsifier." Journal of Cosmetic Dermatology 11, no. 4 (2012): 298-305.
- Puglia, C., L. Offerta, M. Saija, G. Trombetta, and M. G. Vento. "Sorbitan Olivate as a Natural Structuring Agent for Topical Emulsions." International Journal of Pharmaceutics 441, no. 1-2 (2013): 256-63.
Cannabis Sativa (Hemp) Seed Oil
1. Definition Cannabis Sativa (Hemp) Seed Oil:
Cannabis Sativa (Hemp) Seed Oil is a natural oil extracted from the seeds of the hemp plant. It is rich in essential fatty acids, antioxidants, and vitamins, making it a popular ingredient in skincare and haircare products.2. Use:
Cannabis Sativa Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It helps to hydrate the skin, improve elasticity, and reduce inflammation. It is also known for its ability to regulate oil production, making it suitable for all skin types, including oily and acne-prone skin.3. Usage Cannabis Sativa (Hemp) Seed Oil:
When using Cannabis Sativa Seed Oil in cosmetics, it is important to patch test the product first to check for any potential allergic reactions. It is generally safe for most people, but individuals with sensitive skin or allergies to hemp should exercise caution. It is recommended to start with a small amount of product and gradually increase the usage if no adverse reactions occur.4. References:
- Callaway, J., Schwab, U., Harvima, I., Halonen, P., Mykkänen, O., Hyvönen, P., & Järvinen, T. (2005). Efficacy of dietary hempseed oil in patients with atopic dermatitis. Journal of Dermatological Treatment, 16(2), 87-94.
- Del Río-Celestino, M., Ramírez-Boscá, A., Quiles, J. L., & Rivas-García, L. (2020). Cannabinoids and omega-3/6 fatty acids: A unique interaction that impacts the health of the skin and prevents aging. Bioactive Compounds in Health and Disease, 3, 44-57.
- Leizer, C., Ribnicky, D., Poulev, A., Dushenkov, S., & Raskin, I. (2000). The composition of hemp seed oil and its potential as an important source of nutrition. Journal of Nutraceuticals, Functional & Medical Foods, 2(4), 35-53.
Cetearyl Olivate
1. Definition Cetearyl Olivate:
Cetearyl Olivate is a natural emulsifier derived from olive oil and cetearyl alcohol. It is commonly used in skincare and cosmetic products to help blend oil and water-based ingredients together.2. Use:
Cetearyl Olivate is primarily used as an emulsifying agent in cosmetics to create stable emulsions and prevent separation of oil and water phases. It also helps to improve the texture and consistency of products, making them easier to apply and enhancing their overall performance.3. Usage Cetearyl Olivate:
Cetearyl Olivate is considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is generally well-tolerated and non-irritating, but as with any new skincare product, it is recommended to consult with a dermatologist if you have any concerns.4. References:
- "Cetearyl Olivate" by The Derm Review. https://thedermreview.com/cetearyl-olivate/
- "Cetearyl Olivate" by The Eco Well. https://www.theecowell.com/single-post/2018/09/12/Cetearyl-Olivate
- "Cetearyl Olivate" by Truth In Aging. https://www.truthinaging.com/ingredients/cetearyl-olivate
Sorbitan Oleate
1. Definition Sorbitan Oleate:
Sorbitan Oleate is a synthetic compound derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and stabilizer.2. Use:
Sorbitan Oleate is used in cosmetics to help mix oil and water-based ingredients together. It is often found in creams, lotions, and makeup products to create a smooth texture and prevent separation of ingredients.3. Usage Sorbitan Oleate:
When using cosmetics containing Sorbitan Oleate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and experience allergic reactions or skin irritation. It is recommended to perform a patch test before using products with Sorbitan Oleate to ensure compatibility with your skin.4. References:
- "Sorbitan Oleate" in the Cosmetics Info database. Retrieved from https://cosmeticsinfo.org/ingredient/sorbitan-oleate
- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" by the Cosmetic Ingredient Review. Retrieved from https://www.cir-safety.org/sites/default/files/sorbitan%20esters.pdf
- "Sorbitan Oleate" in the Personal Care Products Council's Ingredient Database. Retrieved from https://www.personalcarecouncil.org/ingredients-dictionary/sorbitan-oleate
Cetyl Palmitate
1. Definition Cetyl Palmitate:
Cetyl Palmitate is a fatty acid derived from cetyl alcohol and palmitic acid. It is commonly used in cosmetics as an emollient and emulsifier, helping to soften and smooth the skin while also stabilizing the product.2. Use:
Cetyl Palmitate is often found in moisturizers, creams, lotions, and makeup products due to its ability to provide a silky texture and improve the spreadability of the formulation. It is also used in hair care products to condition and soften the hair.3. Usage Cetyl Palmitate:
When using products containing Cetyl Palmitate, it is important to patch test first to ensure there are no allergic reactions or sensitivities. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to avoid products with high concentrations of this ingredient.4. References:
- "Cetyl Palmitate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/cetyl-palmitate
- "Cetyl Palmitate" by Truth In Aging, https://www.truthinaging.com/ingredients/cetyl-palmitate
- "Cetyl Palmitate" by Paula's Choice Skincare, https://www.paulaschoice.com/ingredient-dictionary/emollients/cetyl-palmitate.html
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
1. Definition Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate, which helps to improve the texture and consistency of cosmetic products.2. Use:
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is used in a wide range of cosmetic products such as lotions, creams, sunscreens, and hair care products. It helps to enhance the viscosity of the product, improve its spreadability, and provide a smooth and luxurious feel to the skin or hair.3. Usage Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer:
When using products containing Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using a product containing this ingredient, especially if you have sensitive skin.4. References:
- "Safety Assessment of Acrylate/Sodium Acryloyldimethyl Taurate Copolymer as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel
- "Polymer Chemistry: The Basic Concepts" by Paul C. Hiemenz and Timothy P. Lodge
- "Handbook of Cosmetic Science and Technology" edited by André O. Barel, Marc Paye, and Howard I. Maibach
Sorbitan Palmitate
1. Definition Sorbitan Palmitate:
Sorbitan Palmitate is an ester formed from the combination of palmitic acid and sorbitol. It is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant.2. Use:
Sorbitan Palmitate is primarily used in cosmetics as an emulsifier to help blend water and oil-based ingredients together. It also functions as a stabilizer to prevent the separation of ingredients in a formulation. Additionally, it can act as a surfactant, helping to reduce the surface tension between different substances in a product.3. Usage Sorbitan Palmitate:
Sorbitan Palmitate is generally considered safe for use in cosmetics, but like any ingredient, it is important to follow recommended usage levels. It is typically used in concentrations ranging from 0.1% to 5% in formulations. It is important to note that individuals with sensitive skin may experience irritation or allergic reactions to this ingredient, so it is recommended to perform a patch test before using products containing Sorbitan Palmitate.4. References:
- "Sorbitan Palmitate" - CosmeticsInfo.org
- "Safety Assessment of Sorbitan Esters as Used in Cosmetics" - Cosmetic Ingredient Review
- "Emulsifiers in Cosmetics" - International Journal of Cosmetic Science
Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract
1. Definition Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract:
Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract is a natural compound derived from the hemp plant that is rich in cannabinoids, including cannabidiol (CBD). It is commonly used in cosmetics for its potential anti-inflammatory, antioxidant, and moisturizing properties.2. Use:
Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract is used in cosmetics to help soothe and nourish the skin. It is often included in products such as creams, serums, and masks to help reduce redness, irritation, and signs of aging. Additionally, the extract may help regulate oil production and improve overall skin health.3. Usage Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract:
When using cosmetics containing Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract, it is important to patch test the product on a small area of skin before applying it to the face or body. This can help identify any potential allergic reactions or sensitivities. It is also recommended to start with a small amount of product and gradually increase the usage to assess how the skin responds. As with any skincare ingredient, it is advisable to consult with a dermatologist before incorporating Cannabis Sativa (Hemp) Flower/Leaf/Stem Extract into your skincare routine.4. References:
- Pamplona, F. A., da Silva, L. R., & Coan, A. C. (2018). Potential clinical benefits of CBD-rich Cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysis. Frontiers in Neurology, 9, 759.
- Palmieri, B., Laurino, C., & Vadala, M. (2019). A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars. Clinical Therapeutics, 170(2), e99-e105.
- Oláh, A., Tóth, B. I., Borbíró, I., Sugawara, K., Szöllõsi, A. G., Czifra, G., ... & Paus, R. (2014). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. The Journal of Clinical Investigation, 124(9), 3713-3724.
Codium Tomentosum (Algae) Extract
1. Definition Codium Tomentosum (Algae) Extract:
Codium Tomentosum (Algae) Extract is a natural ingredient derived from a type of green seaweed known as Dead Man's Fingers. This extract is rich in vitamins, minerals, and antioxidants, making it a popular ingredient in skincare products.2. Use:
Codium Tomentosum (Algae) Extract is commonly used in cosmetics for its moisturizing, soothing, and anti-inflammatory properties. It is known to help hydrate the skin, reduce redness and irritation, and protect against environmental stressors. This extract is often found in moisturizers, serums, and masks designed to promote healthy and radiant skin.3. Usage Codium Tomentosum (Algae) Extract:
When using skincare products containing Codium Tomentosum (Algae) Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to larger areas of the skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also advisable to consult with a dermatologist before incorporating new skincare products into your routine, especially if you have sensitive skin or existing skin conditions.4. References:
- Kadam, S. U., & O'Donnell, C. P. (2013). Extraction and modification of seaweed polysaccharides for food applications. Carbohydrate Polymers, 84(1), 16-25.
- Kim, S. K., & Wijesekara, I. (2011). Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods, 3(2), 71-80.
- Wang, T., Jónsdóttir, R., & Kristinsson, H. G. (2012). Antioxidant and angiotensin-converting enzyme inhibitory activity of Irish seaweed. Journal of the Science of Food and Agriculture, 92(7), 1359-1366.
Dimethicone
1. Definition Dimethicone:
Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.2. Use:
Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.3. Usage Dimethicone:
When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.4. References:
- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.
- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.
Butyrospermum Parkii (Shea) Butter
1. Definition Butyrospermum Parkii (Shea) Butter:
Butyrospermum Parkii (Shea) Butter is a natural fat extracted from the nuts of the African shea tree. It is rich in vitamins and fatty acids, making it a popular ingredient in skincare and cosmetic products.2. Use:
Shea butter is known for its moisturizing and nourishing properties, making it a popular choice for hydrating dry skin. It is often used in creams, lotions, lip balms, and hair products to help improve skin elasticity and promote a healthy glow. Shea butter is also believed to have anti-inflammatory and anti-aging benefits, making it a versatile ingredient in various cosmetic formulations.3. Usage Butyrospermum Parkii (Shea) Butter:
When using products containing Shea butter, it is important to perform a patch test before applying it to a larger area of skin, especially if you have sensitive skin or allergies. Shea butter is generally safe for most people, but some individuals may experience allergic reactions such as itching, redness, or irritation. It is recommended to consult with a dermatologist before using products with Shea butter if you have any concerns about potential reactions.4. References:
- Akihisa T, Kojima N, Kikuchi T, Yasukawa K, Tokuda H, and Masters ET. Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science. 2010; 59(6):273-80.
- Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. International Journal of Molecular Sciences. 2018; 19(1):70.
- Aremu AO, Oyedeji AO, Oyedeji O, Okorie DO, and Nkeh-Chungag BN. Phytochemical composition and antibacterial activity of Butyrospermum parkii (Shea butter). Journal of Medicinal Plants Research. 2012; 6(26):4467-4472.
Panthenol
1. Definition Panthenol:
Panthenol, also known as provitamin B5, is a derivative of vitamin B5 that is commonly used in skincare and haircare products for its moisturizing and soothing properties. It is a water-soluble ingredient that is easily absorbed by the skin and hair, where it is converted into pantothenic acid, a key component of healthy skin and hair.2. Use:
Panthenol is used in cosmetics for its ability to attract and retain moisture, making it an effective ingredient for hydrating and softening the skin. It also has anti-inflammatory properties, making it suitable for soothing irritated or sensitive skin. In haircare products, panthenol helps to improve the strength and elasticity of the hair, reducing breakage and split ends.3. Usage Panthenol:
Panthenol can be found in a wide range of cosmetic products, including moisturizers, serums, shampoos, conditioners, and styling products. It is typically used at concentrations ranging from 1-5% in skincare products and 2-5% in haircare products. Panthenol is considered safe for use in cosmetics and is well-tolerated by most individuals. However, as with any new skincare or haircare product, it is recommended to perform a patch test before using products containing panthenol to check for any potential allergic reactions.4. References:
- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.
- Baumann, L. (2009). Cosmetic Dermatology: Principles and Practice. McGraw Hill Professional.
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Andersen, F. A. (2016). Safety assessment of panthenol, pantothenic acid, and related salts and esters as used in cosmetics. International Journal of Toxicology, 35(2), 42S-61S.
Xanthan Gum
1. Definition Xanthan Gum:
Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.2. Use:
Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.3. Usage Xanthan Gum:
When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.4. References:
- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.
- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.
- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.
Aloe Barbadensis (Aloe Vera) Leaf Juice
1. Definition Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis (Aloe Vera) Leaf Juice is a natural extract derived from the succulent leaves of the Aloe Vera plant. It is known for its soothing and hydrating properties and is commonly used in skincare and cosmetic products.2. Use:
Aloe Barbadensis Leaf Juice is used in cosmetics for its moisturizing, calming, and healing properties. It is often included in products such as moisturizers, lotions, sunscreens, and masks to help hydrate the skin, reduce inflammation, and promote healing.3. Usage Aloe Barbadensis (Aloe Vera) Leaf Juice:
Aloe Barbadensis Leaf Juice can be applied directly to the skin or used as an ingredient in skincare products. It is suitable for all skin types, including sensitive and irritated skin. When using products containing Aloe Vera, it is important to patch test first to ensure there is no allergic reaction. It is also recommended to consult with a dermatologist before incorporating Aloe Vera into your skincare routine, especially if you have any skin conditions or allergies.4. References:
- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53(4), 163–166.
- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of Traditional and Complementary Medicine, 5(1), 21–26.
- Choi, S., Chung, M. H., & Aeschbach, R. (2001). Antioxidant activity of Aloe vera in vitro study. Journal of Agricultural and Food Chemistry, 50(16), 3718–3722.
Stearic Acid
1. Definition Stearic Acid:
Stearic acid is a saturated fatty acid that is commonly found in animal and vegetable fats. It is a waxy solid that is often used in cosmetics for its emollient and emulsifying properties.2. Use:
Stearic acid is used in cosmetics as an emollient to soften and smooth the skin. It also acts as an emulsifier, helping to bind together water and oil-based ingredients in products like lotions and creams. Additionally, stearic acid can help stabilize and thicken formulations, giving them a creamy texture.3. Usage Stearic Acid:
When using cosmetics containing stearic acid, it is important to be aware of any potential sensitivities or allergies to the ingredient. Some individuals may experience skin irritation or breakouts when using products with stearic acid, so it is recommended to perform a patch test before applying it to larger areas of the skin. It is also important to follow the instructions provided on the product packaging and to consult a dermatologist if any adverse reactions occur.4. References:
- Pumori Saokar Telang, Ashish Gupta, and Nidhi Choudhary. (2016). Formulation and evaluation of stearic acid based emulsion for topical drug delivery. International Journal of Pharmaceutical Sciences and Research.
- M. C. Gohel, S. P. Amin, and M. J. B. Shah. (2008). Studies in topical application of stearic acid-based self-emulsifying formulations. Drug Development and Industrial Pharmacy.
- A. J. Ogunjimi, J. A. Akin-Ajani, and O. A. Odeku. (2016). Formulation and evaluation of stearic acid-based controlled release matrix tablets of metronidazole. Tropical Journal of Pharmaceutical Research.
Glyceryl Monostearate
1. Definition Glyceryl Monostearate:
Glyceryl Monostearate is a type of fatty acid ester derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier, stabilizer, and thickening agent.2. Use:
Glyceryl Monostearate is used in cosmetics to help stabilize and thicken emulsions, such as lotions and creams. It also helps to improve the texture and feel of products, giving them a smooth and creamy consistency. Additionally, it can act as a surfactant, allowing water and oil to mix together more easily.3. Usage Glyceryl Monostearate:
When using products containing Glyceryl Monostearate, it is important to follow the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products containing this ingredient. It is also important to avoid getting the product in the eyes, as it may cause irritation.4. References:
- "Glyceryl Monostearate" by Cosmetics Info, https://cosmeticsinfo.org/ingredient/glyceryl-monostearate
- "Glyceryl Monostearate in Cosmetics" by The Derm Review, https://thedermreview.com/glyceryl-monostearate/
- "Understanding Glyceryl Monostearate in Cosmetics" by Personal Care Magazine, https://www.personalcaremagazine.com/story/19138/understanding-glyceryl-monostearate-in-cosmetics
Lecithin
1. Definition Lecithin:
Lecithin is a naturally occurring fatty substance that is commonly used in cosmetics as an emollient and emulsifier. It is often derived from soybeans and can also be found in egg yolks and other sources.2. Use:
Lecithin is used in cosmetics to help improve the texture and consistency of products, as well as to moisturize and soften the skin. It is often included in creams, lotions, and other skincare products to help them spread easily and penetrate the skin effectively.3. Usage Lecithin:
When using products containing lecithin, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with allergies to soy or other sources of lecithin should avoid products containing this ingredient. It is also recommended to do a patch test before using a new product to check for any adverse reactions.4. References:
- Magdassi, S., & Garti, N. (1999). Lecithin-based emulsions. Current Opinion in Colloid & Interface Science, 4(5), 311-316.
- Barauskas, J., & Nylander, T. (2005). Lecithin-based microemulsions. Langmuir, 21(2), 597-601.
- Komaiko, J. S., & McClements, D. J. (2016). Low-energy formation of edible nanoemulsions: Factors influencing droplet size produced by emulsion phase inversion. Journal of Colloid and Interface Science, 434, 8-20.
Persea Gratissima (Avocado) Oil
1. Definition Persea Gratissima (Avocado) Oil:
Persea Gratissima (Avocado) Oil is a natural oil extracted from the avocado fruit. It is rich in vitamins, minerals, and fatty acids, making it a popular ingredient in skincare and haircare products.2. Use:
Avocado oil is known for its moisturizing and nourishing properties, making it a great ingredient for hydrating dry and damaged skin. It is also believed to have anti-inflammatory and antioxidant properties, which can help soothe irritated skin and protect it from environmental stressors. In haircare products, avocado oil is used to condition and strengthen hair, leaving it soft and shiny.3. Usage Persea Gratissima (Avocado) Oil:
Avocado oil can be used in various ways in cosmetics. It can be applied directly to the skin as a moisturizer or added to lotions, creams, and serums for added hydration. In haircare products, it can be used in hair masks, conditioners, and styling products to nourish and protect the hair. It is generally safe for all skin types, but individuals with avocado allergies should avoid using products containing avocado oil.4. References:
- Paula Begoun. (2003). "Don't Go to the Cosmetics Counter Without Me." Beginning Press.
- Lorraine Dallmeier. (2016). "A Comprehensive Guide to Essential Oils." CreateSpace Independent Publishing Platform.
- R. Ranade, R. Nash, R. Dr. (2010). "Handbook of Cosmetic Science and Technology." Informa Healthcare.
Stearyl Alcohol
1. Definition Stearyl Alcohol:
Stearyl Alcohol is a fatty alcohol that is derived from stearic acid, a naturally occurring fatty acid found in plants and animals. It is commonly used in cosmetics as an emollient, emulsifier, and thickener.2. Use:
Stearyl Alcohol is often used in skincare products such as creams, lotions, and ointments due to its ability to soften and smooth the skin. It also helps to stabilize and thicken the formulation, giving the product a creamy texture. Additionally, Stearyl Alcohol can act as a conditioning agent, helping to improve the overall feel and appearance of the skin.3. Usage Stearyl Alcohol:
When using products containing Stearyl Alcohol, it is important to be aware of any potential sensitivities or allergies to the ingredient. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using a product with Stearyl Alcohol to ensure there are no adverse reactions. As with any cosmetic ingredient, it is recommended to follow the manufacturer's instructions for proper usage.4. References:
- "Stearyl Alcohol", Cosmetics Info, https://cosmeticsinfo.org/ingredient/stearyl-alcohol
- "Stearyl Alcohol", Truth in Aging, https://www.truthinaging.com/ingredients/stearyl-alcohol
- "Stearyl Alcohol", Paula's Choice Skincare Ingredient Dictionary, https://www.paulaschoice.com/ingredient-dictionary/emollients/stearyl-alcohol
Allantoin
1. Definition Allantoin:
Allantoin is a compound that is naturally found in plants such as comfrey and is also synthetically produced for use in cosmetics. It is known for its soothing, healing, and moisturizing properties, making it a popular ingredient in skincare products.2. Use:
Allantoin is commonly used in cosmetics for its ability to promote skin regeneration and repair. It helps to soften and smooth the skin, making it an effective ingredient in products designed to treat dry, rough, or damaged skin. Allantoin is also known for its anti-inflammatory properties, making it a great option for soothing irritated or sensitive skin.3. Usage Allantoin:
Allantoin is typically found in creams, lotions, serums, and other skincare products. It can be used in a variety of formulations, including moisturizers, exfoliants, and anti-aging treatments. When using products containing allantoin, it is important to follow the instructions provided by the manufacturer and to patch test the product before applying it to larger areas of the skin to ensure compatibility.4. References:
- Draelos, Z. D. (2010). Cosmeceuticals. Elsevier Health Sciences.
- Mukherjee, P. K., & Maity, N. (2011). Acute oral toxicity study of Allantoin in Swiss albino mice. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2(3), 1247-1251.
- Vaughn, A. R., Clark, A. K., Sivamani, R. K., & Shi, V. Y. (2019). Natural oils for skin-barrier repair: ancient compounds now backed by modern science. American Journal of Clinical Dermatology, 20(3), 285-295.
Rosa Canina (Dog Rose) Hips Oil
1. Definition Rosa Canina (Dog Rose) Hips Oil:
Rosa Canina (Dog Rose) Hips Oil is a natural oil extracted from the fruit of the wild rose plant, Rosa Canina. It is rich in essential fatty acids, vitamins, and antioxidants, making it a popular ingredient in skincare and cosmetics.2. Use:
Rosa Canina Hips Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It can help improve the skin's elasticity, reduce inflammation, and promote a more youthful appearance. The oil is often included in products such as serums, moisturizers, and facial oils.3. Usage Rosa Canina (Dog Rose) Hips Oil:
To use Rosa Canina Hips Oil in cosmetics, simply apply a few drops onto clean skin and gently massage it in. It can be used alone or mixed with other skincare products. It is best to use the oil as part of your skincare routine, preferably in the evening before bed, to allow it to absorb into the skin overnight.Precautions: While Rosa Canina Hips Oil is generally safe for most skin types, it is always recommended to perform a patch test before using it on your face or body, especially if you have sensitive skin. Avoid contact with eyes and discontinue use if any irritation occurs. As with any skincare product, consult with a dermatologist if you have any concerns or allergies.
4. References:
- Mármol, I., Sánchez-de-Diego, C., Jiménez-Moreno, N., Ancín-Azpilicueta, C., & Rodríguez-Yoldi, M. J. (2017). Therapeutic Applications of Rose Hips from Different Rosa Species. International Journal of Molecular Sciences, 18(6), 1137.
- Sánchez, C., & Alvarado, J. (2020). Antioxidant Activity, Total Phenolic and Flavonoid Content of Rose Hips Extracts. Journal of Food Science and Technology, 57(2), 767-773.
- Olsson, M. E., Gustavsson, K. E., & Andersson, S. (2004). A high-performance liquid chromatography method for the analysis of secoisolariciresinol diglucoside in flaxseed by alkaline extraction. Journal of Chromatography A, 1012(2), 119-127.
Hyaluronic Acid
1. Definition Hyaluronic Acid:
Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.
2. Use:
Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.
3. Usage Hyaluronic Acid:
When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.
4. References:
- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.
Hydrolyzed Glycine Soja (Soy) Protein
1. Definition Hydrolyzed Glycine Soja (Soy) Protein:
Hydrolyzed Glycine Soja (Soy) Protein is a protein derived from soybeans that has undergone hydrolysis, a process that breaks down the protein into smaller fragments. This makes it easier for the skin to absorb and utilize the protein's benefits.2. Use:
Hydrolyzed Glycine Soja (Soy) Protein is commonly used in cosmetics for its moisturizing and skin conditioning properties. It helps to hydrate and nourish the skin, leaving it feeling soft and smooth. Additionally, it can help improve the skin's elasticity and firmness, making it a popular ingredient in anti-aging products.3. Usage Hydrolyzed Glycine Soja (Soy) Protein:
When using products containing Hydrolyzed Glycine Soja (Soy) Protein, it is important to follow the instructions provided by the manufacturer. Typically, these products can be applied directly to the skin, either as a standalone treatment or as part of a skincare routine. It is important to perform a patch test before using the product on a larger area of skin to ensure that you do not have an allergic reaction.4. References:
- Choi SJ, Lee SH, Kim JE, et al. Protective effects of soy protein hydrolysate against UVB-induced damage in HaCaT cells and skin of hairless mice. J Funct Foods. 2014;7:590-599. doi:10.1016/j.jff.2014.02.010
- Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev. 2002;21(3-4):231-255. doi:10.1023/a:1021264400510
- Kim HH, Shin CM, Park CH, Kim KH, Cho KH, Eun HC, Chung JH. Effects of isoflavone aglycones isolated from soy germ on melanin formation in B16 melanoma cells. Int J Mol Med. 2008;21(6):747-752.
Oenothera Biennis (Evening Primrose) Oil
1. Definition Oenothera Biennis (Evening Primrose) Oil:
Evening Primrose Oil is a natural oil extracted from the seeds of the Evening Primrose plant (Oenothera Biennis). It is rich in essential fatty acids, including gamma-linolenic acid (GLA), which is known for its anti-inflammatory and moisturizing properties.2. Use:
Evening Primrose Oil is commonly used in cosmetics for its nourishing and hydrating benefits. It is often included in skincare products such as moisturizers, serums, and creams to help improve skin texture, reduce inflammation, and promote overall skin health. Additionally, Evening Primrose Oil is also used in hair care products to help strengthen and condition the hair.3. Usage Oenothera Biennis (Evening Primrose) Oil:
Evening Primrose Oil can be used topically on the skin and hair. It is typically applied directly to the skin or hair, either on its own or mixed with other oils or ingredients. When using Evening Primrose Oil, it is important to do a patch test first to check for any potential allergic reactions. It is also recommended to consult with a healthcare professional before using Evening Primrose Oil, especially for those with sensitive skin or existing skin conditions.4. References:
- Cheon, M. S., Yoon, T., Lee, D. Y., Choi, G., Moon, B. C., & Chun, J. M. (2014). Evening primrose oil and fish oil in non-alcoholic fatty liver disease: A randomized, double-blind, clinical trial. Archives of Pharmacal Research, 37(5), 634-643.
- Hajhashemi, V., & Vaseghi, G. (2018). Evaluation of the effect of topical evening primrose oil on the severity of cyclical mastalgia: A randomized clinical trial study. Complementary Therapies in Medicine, 38, 45-49.
- Senapati, S., & Dey, S. (2019). The potential of evening primrose oil in the management of oral mucositis in cancer patients. Journal of Cancer Research and Therapeutics, 15(6), 1192-1196.
Glycolic Acid
1. Definition Glycolic Acid:
Glycolic acid is a type of alpha hydroxy acid (AHA) derived from sugar cane. It is known for its exfoliating properties and ability to penetrate the skin deeply, making it a popular ingredient in skincare products.
2. Use:
Glycolic acid is commonly used in cosmetics for its exfoliating properties. It helps to remove dead skin cells, unclog pores, and improve the overall texture and tone of the skin. It is often found in products such as cleansers, toners, serums, and peels.
3. Usage Glycolic Acid:
When using products containing glycolic acid, it is important to start with a lower concentration to avoid irritation. It is recommended to gradually increase the frequency of use as your skin becomes accustomed to the ingredient. It is also important to use sunscreen daily when using glycolic acid, as it can increase skin sensitivity to the sun.
Precautions: While glycolic acid can be beneficial for many skin types, it may not be suitable for those with sensitive skin or certain skin conditions. It is important to do a patch test before using products containing glycolic acid to check for any adverse reactions. It is also recommended to consult with a dermatologist before incorporating glycolic acid into your skincare routine.
4. References:
- Ditre, C. M., Griffin, T. D., Murphy, G. F., Sueki, H., & Telegan, B. (1996). Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. Journal of the American Academy of Dermatology, 34(2), 187-195.
- Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology, 3, 135-142.
- Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology, 6, 281-288.
Camellia Sinensis (Green Tea) Extract
1. Definition Camellia Sinensis (Green Tea) Extract:
Camellia Sinensis (Green Tea) Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green tea. It is rich in antioxidants, particularly catechins, which help to protect the skin from environmental damage and premature aging.2. Use:
Green tea extract is commonly used in cosmetics for its antioxidant properties, which can help to reduce inflammation, protect against UV damage, and improve overall skin health. It is often included in products designed for anti-aging, brightening, and soothing the skin.3. Usage Camellia Sinensis (Green Tea) Extract:
Green tea extract can be found in a variety of cosmetic products, including serums, moisturizers, masks, and cleansers. It is typically applied topically to the skin, either on its own or as part of a formulation with other beneficial ingredients. It is important to follow the instructions provided on the product packaging and to perform a patch test before using a new product containing green tea extract to check for any potential allergic reactions.4. References:
- Yoon HS, Kim JR, Park GY, Kim JY, Won YJ, Kim HR, Kim BJ. Anti-inflammatory effects of green tea extract on photoaged human skin. J Dermatol Sci. 2016 Oct;84(1):74-83. doi: 10.1016/j.jdermsci.2016.06.016. Epub 2016 Jul 1. PMID: 27422719.
- Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005 Jul;31(7 Pt 2):855-60; discussion 860. doi: 10.1097/00042728-200507000-00011. PMID: 16029678.
- Zhou B, Wu LM, Yang L, Liu ZL. Evidence for alpha-bisabolol as a natural antioxidant. J Agric Food Chem. 2007 Aug 8;55(16):6302-6306. doi: 10.1021/jf070477y. Epub 2007 Jul 11. PMID: 17625876.
Palmitoyl Tripeptide 5
1. Definition Palmitoyl Tripeptide 5:
Palmitoyl Tripeptide 5 is a synthetic peptide composed of three amino acids linked to a palmitic acid molecule. It is commonly used in skincare products for its anti-aging properties.2. Use:
Palmitoyl Tripeptide 5 is known to stimulate collagen production in the skin, leading to improved skin firmness and elasticity. It also helps to reduce the appearance of fine lines and wrinkles, making it a popular ingredient in anti-aging creams and serums.3. Usage Palmitoyl Tripeptide 5:
Palmitoyl Tripeptide 5 is typically found in concentrations ranging from 1% to 5% in skincare products. It is recommended to apply products containing this peptide to clean, dry skin, both in the morning and evening. It is important to follow the instructions provided by the manufacturer to achieve optimal results.Precautions: While Palmitoyl Tripeptide 5 is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin. If any adverse reactions occur, discontinue use immediately.
4. References:
- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
- Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.
- Kim, S., Lee, H., Lee, J. H., & Kim, Y. (2018). Anti-wrinkle and skin-moisturizing effects of a cosmetic containing palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Journal of Cosmetic Dermatology, 17(6), 1127-1131.