Andrographolide

1. Definition Andrographolide:

Andrographolide is a bioactive compound derived from the herb Andrographis paniculata, also known as the king of bitters. It is known for its potent anti-inflammatory, antioxidant, and antibacterial properties.

2. Use:

Andrographolide is commonly used in cosmetics for its anti-inflammatory properties, which can help reduce redness, swelling, and irritation on the skin. It also acts as an antioxidant, protecting the skin from free radical damage and premature aging. Additionally, its antibacterial properties make it effective in fighting acne-causing bacteria and promoting clear, healthy skin.

3. Usage Andrographolide:

When using cosmetics containing andrographolide, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying it to a larger area of the skin to check for any potential allergic reactions. It is also advisable to consult with a dermatologist before incorporating products with andrographolide into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Chen, Y., Lu, Y., Chen, J., & Lai, Z. (2019). Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway. Evidence-Based Complementary and Alternative Medicine, 2019.

- Akbar, S., Andrographis paniculata: A Review of its Traditional Uses, Phytochemistry and Pharmacology. Medicinal & Aromatic Plants, 2015.

- Mishra, K., Dash, A. P., Dey, N. (2009). Andrographolide: A Novel Antimalarial Diterpene Lactone Compound from Andrographis paniculata and its interaction with curcumin and artesunate. Journal of Tropical Medicine and Parasitology, 32(2), 100-104.