Cetylhydroxyproline Palmitamide

1. Definition Cetylhydroxyproline Palmitamide:

Cetylhydroxyproline Palmitamide, also known as Ceramide AP, is a synthetic ceramide that is commonly used in cosmetics for its skin-replenishing and moisturizing properties. Ceramides are lipids that naturally occur in the skin and play a crucial role in maintaining its barrier function and hydration levels.

2. Use:

Cetylhydroxyproline Palmitamide is often included in skincare products such as moisturizers, serums, and creams to help strengthen the skin's barrier, improve its moisture retention, and enhance its overall appearance. This ingredient is particularly beneficial for individuals with dry, dehydrated, or sensitive skin, as it can help restore and maintain the skin's natural lipid balance.

3. Usage Cetylhydroxyproline Palmitamide:

When using products containing Cetylhydroxyproline Palmitamide, it is important to follow the manufacturer's instructions and recommendations. Typically, this ingredient can be found in various concentrations in skincare formulations, so it is essential to start with a lower concentration and gradually increase usage if needed. It is advisable to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or sensitivities.

4. References:

- Sivakumar B, Aswathy KS, Krishna SK, et al. Ceramides and skin barrier function: implications for skin disease and skin health. Int J Mol Sci. 2019;20(20):5427. doi:10.3390/ijms20205427

- Yosipovitch G, Maayan-Metzger A, Merlob P, Sirota L. Skin barrier properties in different body areas in neonates. Pediatrics. 2000;106(1 Pt 1):105-108. doi:10.1542/peds.106.1.105

- Motta S, Monti M, Sesana S, et al. Ceramide composition of the psoriatic scale. Biochim Biophys Acta. 1993;1182(2):147-151. doi:10.1016/0005-2760(93)90239-9