Dihydromyricetin

1. Definition Dihydromyricetin:

Dihydromyricetin, also known as DHM, is a natural flavonoid compound found in the Ampelopsis grossedentata plant. It has been traditionally used in Chinese medicine for its antioxidant and anti-inflammatory properties.

2. Use:

Dihydromyricetin is commonly used in cosmetics for its ability to protect the skin from environmental stressors and UV radiation. It also has anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Dihydromyricetin:

When using dihydromyricetin in cosmetics, it is important to follow the recommended dosage and application instructions provided by the manufacturer. It is generally safe for topical use, but individuals with sensitive skin may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing dihydromyricetin on a larger area of the skin.

4. References:

- Chen, Y., Zhang, A., Wang, Y., & Zhang, J. (2018). Dihydromyricetin protects against bone loss in ovariectomized mice by suppressing osteoclast activity. Frontiers in Pharmacology, 9, 1010.

- Zhang, X., Zhang, Y., Li, Y., & Ding, J. (2019). Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway. Oncology Reports, 41(4), 2475-2486.

- Wang, Y., Xie, Y., Luo, J., & Li, Y. (2020). Dihydromyricetin inhibits the proliferation of hepatocellular carcinoma cells by inducing apoptosis and cell cycle arrest. Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology, 25(3), 1369-1374.