Diosmetin

1. Definition Diosmetin:

Diosmetin is a flavonoid compound found in various plants, including citrus fruits and parsley. It is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Diosmetin is commonly used in cosmetics for its ability to protect the skin from oxidative stress and reduce inflammation. It is often included in anti-aging products due to its ability to combat free radicals and promote collagen production, leading to smoother and more youthful-looking skin.

3. Usage Diosmetin:

When using cosmetics containing Diosmetin, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test on a small area of skin before applying it to the entire face to check for any potential allergic reactions. Additionally, it is advisable to consult with a dermatologist before incorporating Diosmetin-based products into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Park, J. Y., Shin, M. S., Kim, S. N., Kim, H. Y., Kim, K. H., & Bae, Y. S. (2015). Anti-wrinkle effect of Diospyros kaki Thunb. extract and its constituent, Diosmetin, in UVB-irradiated human skin fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 148, 351-358.

- Kwon, S. H., Lee, H. S., Kim, J. A., Hong, S. I., Kim, H. C., Jo, Y. H., ... & Lee, C. K. (2006). Protective effect of Diosmetin on UVB-induced damage in vitro and in vivo. Journal of Photochemistry and Photobiology B: Biology, 84(3), 165-173.

- Li, Y., Zhang, T., Jiang, Y., Lee, H. F., Schwartz, S. J., & Sun, D. (2011). Diosmetin inhibits the expression of COX-2 and the production of NO in LPS-induced RAW 264.7 cells via NF-κB inactivation. Food and Chemical Toxicology, 49(1), 243-251.