Fibronectin

1. Definition Fibronectin:

Fibronectin is a glycoprotein found in the extracellular matrix of animal tissues. It plays a crucial role in cell adhesion, growth, migration, and differentiation.

2. Use:

In cosmetics, fibronectin is used for its ability to promote skin regeneration and repair. It helps to improve the appearance of fine lines, wrinkles, and scars by stimulating collagen production and enhancing skin elasticity.

3. Usage Fibronectin:

Fibronectin is typically included in anti-aging skincare products such as serums, creams, and masks. It is applied topically to the skin, where it can penetrate the epidermis and interact with skin cells to promote healing and rejuvenation. It is important to follow the manufacturer's instructions for use and to perform a patch test before applying products containing fibronectin to the entire face to avoid any potential allergic reactions or skin irritation.

4. References:

- Kim HH, Lee Y, Eun HC, Chung JH. Efficacy and safety of fibronectin in antiaging treatment. Dermatol Surg. 2011;37(12):1773-81. doi: 10.1111/j.1524-4725.2011.02138.x.

- Park J, Kim M, Na J, et al. Fibronectin peptide-mediated delivery of siRNA/miRNA targeting anti-apoptotic Bcl-2 through neural stem cell differentiation. Mol Ther. 2010;18(11):1854-64. doi: 10.1038/mt.2010.135.

- Yoon HS, Cho HH, Kim HK, et al. Fibronectin stimulates human hair growth through the expression of growth factor genes. Int J Mol Sci. 2018;19(2):535. doi: 10.3390/ijms19020535.