Melatonin

1. Definition Melatonin:

Melatonin is a hormone naturally produced by the pineal gland in the brain that regulates sleep-wake cycles. In recent years, melatonin has gained popularity in the cosmetic industry for its potential anti-aging and skin-repairing properties.

2. Use:

Melatonin is used in cosmetics for its antioxidant and anti-inflammatory properties. It is believed to help protect the skin from environmental damage, reduce signs of aging, and promote skin repair and regeneration. Melatonin is often included in skincare products such as serums, creams, and masks to help improve the overall health and appearance of the skin.

3. Usage Melatonin:

When using cosmetics containing melatonin, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and to use it as part of a regular skincare routine. Some individuals may experience sensitivity to melatonin, so it is advisable to perform a patch test before applying the product to the entire face. It is also important to consult with a dermatologist before incorporating melatonin into your skincare regimen, especially if you have any underlying skin conditions or concerns.

4. References:

- Gomes, A. P., Duarte, I. D., & Perez, A. C. (2014). Potential use of melatonin in skin cancer treatment: a review. Expert Review of Anticancer Therapy, 14(8), 957-965.

- Fischer, T. W., et al. (2001). Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin. Journal of Pineal Research, 31(3), 236-240.

- Kleszczynski, K., Tukaj, S., & Kruse, N. (2016). The use of melatonin in skin care formulations: clinical and in vitro approaches. Skin Pharmacology and Physiology, 29(3), 147-158.