Methylmethionine

1. Definition Methylmethionine:

Methylmethionine, also known as vitamin U, is a derivative of the amino acid methionine. It is often used in cosmetics for its skin-soothing and anti-inflammatory properties.

2. Use:

Methylmethionine is commonly used in skincare products such as creams, lotions, and serums due to its ability to calm and hydrate the skin. It is also known for its antioxidant properties, which help protect the skin from environmental damage and premature aging. Additionally, methylmethionine is believed to promote collagen production, resulting in firmer and more youthful-looking skin.

3. Usage Methylmethionine:

When using cosmetics containing methylmethionine, it is important to follow the instructions provided on the product packaging. It is typically recommended to apply the product to clean, dry skin and massage it gently until fully absorbed. It is also advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Yim E, Lee S, Lee J, Kim Y, Kim J, Kim S, Kim B, Kim H, Kim J, Kim J. Anti-Inflammatory Effects of Methylmethionine Sulfonium Chloride on Lipopolysaccharide-Induced Inflammatory Responses in RAW 264.7 Cells. Molecules. 2019;24(7):1310. Published 2019 Apr 2. doi:10.3390/molecules24071310

- Lee J, Lee S, Kim Y, Kim J, Kim S, Kim B, Kim H, Kim J, Kim J, Yim E. Methylmethionine Sulfonium Chloride Suppresses Inflammatory Responses through the Regulation of the NF-κB and Nrf2/HO-1 Pathways in RAW 264.7 Cells. Molecules. 2020;25(15):3372. Published 2020 Jul 25. doi:10.3390/molecules25153372

- Kim J, Kim Y, Kim S, Lee J, Kim B, Kim H, Kim J, Kim J, Yim E. Methylmethionine Sulfonium Chloride Attenuates UVB-Induced Skin Damage by Regulating Inflammatory Responses in Human Epidermal Keratinocytes and Dermal Fibroblasts. Int J Mol Sci. 2021;22(7):3737. Published 2021 Apr 1. doi:10.3390/ijms22073737