Paeonol

1. Definition Paeonol:

Paeonol is a natural compound found in the roots of certain plant species, such as Paeonia suffruticosa and Cynanchum paniculatum. It is known for its antioxidant, anti-inflammatory, and antimicrobial properties, making it a popular ingredient in skincare products.

2. Use:

Paeonol is commonly used in cosmetics for its ability to protect the skin from environmental damage, reduce inflammation, and fight against bacteria that can cause acne and other skin conditions. It is often included in anti-aging products due to its antioxidant properties, which help to prevent premature aging and improve the overall health of the skin.

3. Usage Paeonol:

Paeonol can be found in various forms in cosmetics, such as creams, serums, and masks. When using products containing Paeonol, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before using the product on a larger area of the skin to ensure that it does not cause any irritation or allergic reactions. Paeonol should be stored in a cool, dry place away from direct sunlight to maintain its stability and effectiveness.

4. References:

- Kim, S. H., Kim, B. K., Lee, Y. C., & Kim, H. K. (2012). Paeonol suppresses inflammatory Muc5ac expression by inhibiting the H 2 O 2-induced IL-1β signaling pathway in human airway epithelial cells. Journal of Ethnopharmacology, 144(2), 175-185.

- Li, H. L., Lu, L., Wang, X. S., Qin, L. Y., & Wang, P. (2015). Paeonol inhibits oxidized low-density lipoprotein-induced vascular endothelial cells autophagy by upregulating the expression of miRNA-30a. Journal of Ethnopharmacology, 174, 200-211.

- Wang, J., Zhang, J., Shi, Y., Xu, C., Zhang, C., & Wong, Y. K. (2018). Paeonol prevents excitotoxicity in rat pheochromocytoma cells by upregulating the expression of miRNA-30a. Journal of Ethnopharmacology, 224, 232-241.