Ruscogenin

1. Definition Ruscogenin:

Ruscogenin is a natural compound derived from the roots of Ruscus aculeatus, also known as Butcher's Broom. It is a steroidal saponin with anti-inflammatory and vasoconstrictive properties.

2. Use:

Ruscogenin is commonly used in cosmetics for its ability to reduce puffiness and dark circles around the eyes. It is also known for its skin-soothing properties and can help improve the appearance of skin texture.

3. Usage Ruscogenin:

Ruscogenin is typically found in eye creams, serums, and gels targeting under-eye bags and dark circles. It is recommended to use products containing ruscogenin as directed by the manufacturer. It is important to perform a patch test before using any new product to ensure compatibility with your skin.

Precautions: While ruscogenin is generally considered safe for topical use, some individuals may experience irritation or allergic reactions. It is advisable to consult with a dermatologist before incorporating products containing ruscogenin into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- Chen, L., Li, J., Zhang, J., Dai, C., Liu, X., & Wang, S. (2016). Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat. BMC Complementary and Alternative Medicine, 16(1), 59.

- Kim, J., Kim, J., & Kim, C. S. (2018). Ruscogenin reduces cerebral ischemic injury via NF-κB-mediated inflammatory pathway in the mouse hippocampus. European Journal of Pharmacology, 819, 1-8.

- Yang, L., & Cai, X. (2019). Ruscogenin inhibits the inflammatory response in BV2 microglia under OGD/R conditions through the suppression of the TLR4 signaling pathway. Molecular Medicine Reports, 20(1), 739-746.