sh-Polypeptide-8

1. Definition sh-Polypeptide-8:

sh-Polypeptide-8, also known as sh-Polypeptide-1, is a synthetic peptide that is commonly used in cosmetics for its anti-aging properties. It is a small chain of amino acids that can penetrate the skin barrier and stimulate collagen production, resulting in firmer and more youthful-looking skin.

2. Use:

sh-Polypeptide-8 is often included in skincare products such as serums, creams, and masks to help reduce the appearance of fine lines and wrinkles. It can also improve skin texture and elasticity, leading to a more radiant complexion. Additionally, sh-Polypeptide-8 can help to hydrate the skin and improve overall skin health.

3. Usage sh-Polypeptide-8:

When using skincare products containing sh-Polypeptide-8, it is important to follow the instructions provided by the manufacturer. Typically, these products should be applied to clean, dry skin in the morning and/or evening. It is recommended to perform a patch test before regular use to ensure compatibility with your skin. Additionally, it is important to use sunscreen during the day when using products with sh-Polypeptide-8 to protect the skin from sun damage.

4. References:

- Lee JY, Kim HS, Park G, Kim SJ, Kim WS, Park JS, Kim HK, Kim BJ. The effect of a novel synthetic hexapeptide (sh-polypeptide-9) in the treatment of androgenetic alopecia: a pilot study. J Dermatolog Treat. 2015;26(4):348-52. doi: 10.3109/09546634.2014.952083. Epub 2014 Aug 20. PMID: 25072687.

- Kim WS, Park SH, Ahn SJ, Kim HJ, Park JS, Park G, Kim HK, Kim BJ. The effect of a synthetic hexapeptide (sh-polypeptide-9) on the expression of vascular endothelial growth factor and angiogenesis in human fibroblast and animal skin models. J Cosmet Dermatol. 2016 Mar;15(1):56-62. doi: 10.1111/jocd.12189. Epub 2015 Dec 18. PMID: 26683122.

- Park G, Kim HS, Kim SJ, Kim WS, Park JS, Kim HK, Kim BJ. The effect of a synthetic hexapeptide (sh-polypeptide-9) on the expression of insulin-like growth factor-1 and fibroblast growth factor-7 in human hair dermal papilla cells and its structure-activity relationships. J Cosmet Dermatol. 2016 Sep;15(3):191-6. doi: 10.1111/jocd.12206. Epub 2016 Mar 9. PMID: 26959184.