Sodium Methylesculetin Acetate

1. Definition Sodium Methylesculetin Acetate:

Sodium Methylesculetin Acetate is a synthetic compound derived from esculetin, a natural coumarin found in various plants. It is commonly used in cosmetics for its skin-lightening and antioxidant properties.

2. Use:

Sodium Methylesculetin Acetate is primarily used in skincare products such as serums, creams, and lotions to help brighten and even out skin tone. It is known for its ability to inhibit the production of melanin, the pigment responsible for dark spots and hyperpigmentation, making it an effective ingredient in products targeting skin discoloration.

3. Usage Sodium Methylesculetin Acetate:

When using products containing Sodium Methylesculetin Acetate, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions or irritation. It is also advisable to use sunscreen during the day when using products with this ingredient, as it may increase the skin's sensitivity to UV radiation.

4. References:

- Kim, D. S., & Kim, S. Y. (2018). Esculetin, a coumarin derivative, inhibits the production of melanin in melanocyte cells. International journal of molecular sciences, 19(4), 1089.

- Lee, J. H., & Cho, S. H. (2013). Esculetin induces long-lasting inactivation of melanogenesis in melanoma cells by regulating tyrosinase activity and down-regulating melanosome transfer. Phytotherapy Research, 27(8), 1158-1163.

- Yang, Y., Kim, H. J., & Kim, J. H. (2017). Esculetin suppresses UVB-induced matrix metalloproteinase-1/3 expressions and collagen degradation in human dermal fibroblasts. Journal of photochemistry and photobiology B: Biology, 174, 1-6.