Tetramethylpyrazine

1. Definition Tetramethylpyrazine:

Tetramethylpyrazine, also known as ligustrazine, is a natural compound derived from the rhizome of Ligusticum chuanxiong Hort, a traditional Chinese medicinal herb. It is a colorless liquid with a distinct odor, commonly used in cosmetics for its antioxidant and anti-inflammatory properties.

2. Use:

Tetramethylpyrazine is used in cosmetics as an active ingredient to help protect the skin from environmental stressors and reduce inflammation. It is often included in skincare products such as serums, creams, and lotions to promote overall skin health and appearance.

3. Usage Tetramethylpyrazine:

When using cosmetics containing tetramethylpyrazine, it is important to follow the instructions provided on the product packaging. It is recommended to perform a patch test before applying the product to the entire face or body to check for any potential allergic reactions. Tetramethylpyrazine should be stored in a cool, dry place away from direct sunlight to maintain its efficacy.

4. References:

- Liu, X., & Zhang, D. (2016). Tetramethylpyrazine inhibits the growth of human liver cancer cells by inducing apoptosis and autophagy. Biomedicine & Pharmacotherapy, 83, 829-835.

- Wang, Y., & Xu, L. (2019). Tetramethylpyrazine protects against lipopolysaccharide-induced acute lung injury by inhibiting the NF-κB pathway. International Immunopharmacology, 69, 11-18.

- Zhang, D., & Liu, X. (2017). Tetramethylpyrazine suppresses adhesion and invasion of hepatoma cells by inhibiting the β-catenin pathway. Biomedicine & Pharmacotherapy, 96, 1223-1229.