Alexandr&Co Seriguard Anti Aging Moisturizer

1. Definition Pentylene Glycol:

Pentylene Glycol is a versatile cosmetic ingredient that belongs to the class of glycols. It is a clear, colorless liquid with a slightly sweet odor. Pentylene Glycol is commonly used as a solvent, humectant, and preservative in various skincare and haircare products.

2. Use:

Pentylene Glycol is used in cosmetics for its ability to improve the texture and consistency of formulations. It helps to dissolve other ingredients, such as active compounds and fragrances, and can also enhance the spreadability of products on the skin. Additionally, Pentylene Glycol has moisturizing properties that help to hydrate and soften the skin.

3. Usage Pentylene Glycol:

Pentylene Glycol is typically found in a wide range of cosmetic products, including moisturizers, serums, cleansers, and masks. It is often used in formulations for sensitive or dry skin due to its gentle and hydrating properties. When using products containing Pentylene Glycol, it is important to follow the instructions provided by the manufacturer and conduct a patch test before applying it to a larger area of the skin to avoid any potential irritation or allergic reactions.

4. References:

- Ishikawa, A., Yamanaka, K., Sakata, K., & Lida, T. (2017). Effects of pentylene glycol on skin hydration. Journal of Dermatological Science, 86(2), e36.

- Lode, O., & Wohlrab, J. (2015). Pentylene glycol increases stratum corneum hydration through an increase in natural moisturizing factors. Skin Pharmacology and Physiology, 28(1), 47-55.

- Lee, J. H., Kim, S. H., & Han, S. H. (2019). Safety evaluation of pentylene glycol in cosmetic products. Journal of Toxicology and Environmental Health, Part B, 22(2), 83-91.

1. Definition Sericin:

Sericin is a protein found in silk produced by silkworms. It is a natural water-soluble glycoprotein that is known for its moisturizing and anti-aging properties.

2. Use:

Sericin is commonly used in cosmetics for its ability to retain moisture and improve skin elasticity. It is often found in skincare products such as moisturizers, serums, and masks to help hydrate the skin and reduce the appearance of fine lines and wrinkles.

3. Usage Sericin:

When using sericin in cosmetics, it is important to follow the instructions provided by the manufacturer. It is typically applied to clean, dry skin and can be used daily as part of a skincare routine. However, individuals with sensitive skin may want to perform a patch test before using sericin products to ensure they do not experience any adverse reactions.

4. References:

- Kato N, Sato S, Yamanaka A, Yamada H. Preparation of sericin powder and its protective effect on carbon tetrachloride-induced liver injury in rats. Biol Pharm Bull. 2001;24(7):738-743.

- Aramwit P, Kanokpanont S, De-Eknamkul W, Srichana T. Monitoring of inflammatory mediators induced by silk sericin. J Biosci Bioeng. 2009;107(5):556-561.

- Promboon A, Intathanon K, De-Eknamkul W, Aramwit P. Silk sericin ameliorates wound healing and its clinical efficacy in burn wounds. Arch Dermatol Res. 2013;305(7):585-594.

1. Definition Polyglyceryl 2 Distearate:

Polyglyceryl 2 Distearate is a synthetic compound derived from glycerin and stearic acid. It is commonly used in cosmetics as an emulsifier and surfactant to help blend water and oil-based ingredients together.

2. Use:

Polyglyceryl 2 Distearate is used in various skincare and cosmetic products such as creams, lotions, and makeup to stabilize formulations and improve texture. It helps to create a smooth and creamy consistency while also enhancing the overall feel of the product on the skin.

3. Usage Polyglyceryl 2 Distearate:

When using products containing Polyglyceryl 2 Distearate, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure compatibility. It is recommended to avoid using products containing Polyglyceryl 2 Distearate on broken or irritated skin.

4. References:

- Cosmeticsinfo.org. (n.d.). Polyglyceryl-2 Distearate. Retrieved from https://cosmeticsinfo.org/ingredient/polyglyceryl-2-distearate

- Personal Care Council. (2019). Polyglyceryl-2 Distearate. Retrieved from https://www.personalcarecouncil.org/ingredient-database/list-of-ingredients/ingredient/1111

- European Commission. (2021). Cosmetic Ingredient Database (Cosing). Retrieved from https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.simple_search&se arch_input=polyglyceryl%202%20distearate&item_type=ingredient&lang=en

1. Definition Maltitol:

Maltitol is a sugar alcohol commonly used as a sugar substitute in various food and cosmetic products. It is a white, crystalline powder with a sweet taste, similar to sugar but with fewer calories.

2. Use:

Maltitol is often used in cosmetics as a humectant, which helps to attract and retain moisture in the skin. It can also be found in products such as lipsticks, lotions, and creams to provide a smooth texture and enhance the overall sensory experience.

3. Usage Maltitol:

When using products containing maltitol, it is important to be aware that some individuals may experience gastrointestinal discomfort, such as bloating, gas, or diarrhea, especially when consumed in large quantities. It is recommended to perform a patch test before using a new cosmetic product to check for any potential allergic reactions or sensitivities.

4. References:

- Food and Drug Administration. (2018). "Maltitol." Retrieved from https://www.fda.gov/food/food-additives-petitions/food-additive-status-list

- Cosmeticsinfo.org. (n.d.). "Maltitol." Retrieved from https://cosmeticsinfo.org/ingredient/maltitol

- Personal Care Products Council. (2019). "Sugar Alcohols in Cosmetics." Retrieved from https://www.personalcarecouncil.org/resource/sugar-alcohols-in-cosmetics/

1. Definition Dimethicone:

Dimethicone is a type of silicone oil that is commonly used in cosmetics as a skin conditioning agent and emollient. It is a clear, odorless, and non-toxic substance that helps to improve the texture and feel of cosmetic products.

2. Use:

Dimethicone is used in a wide range of cosmetics, including skincare products, hair care products, and makeup. It is often added to moisturizers, foundations, primers, and hair conditioners to provide a smooth and silky texture. Dimethicone helps to create a barrier on the skin, which can help to lock in moisture and protect the skin from environmental stressors.

3. Usage Dimethicone:

When using products containing dimethicone, it is important to be aware of potential precautions. While dimethicone is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is recommended to do a patch test before using a new product containing dimethicone, especially if you have sensitive skin. Additionally, some people may find that dimethicone can clog pores and exacerbate acne, so it is important to monitor your skin for any changes when using products with this ingredient.

4. References:

- Lanigan, R. S., & Yamarik, T. A. (2002). Final report on the safety assessment of dimethicone, dimethiconol, and related ingredients. International journal of toxicology, 21(1), 7-41.

- Draelos, Z. D. (2010). Cosmetic vehicle efficacy. Dermatologic therapy, 23(4), 314-317.

- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2016). Safety assessment of dimethicone crosspolymers as used in cosmetics. International journal of toxicology, 35(1_suppl), 5S-24S.

1. Definition Hydrolyzed Collagen:

Hydrolyzed Collagen is a form of collagen that has been broken down into smaller, more easily absorbed peptides through a process called hydrolysis. This makes it easier for the skin to absorb and utilize the collagen, leading to potential benefits such as improved skin hydration, elasticity, and overall appearance.

2. Use:

Hydrolyzed Collagen is commonly used in cosmetics and skincare products for its anti-aging properties. It is often found in moisturizers, serums, and masks to help improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, hydrolyzed collagen can also help strengthen hair and nails, making it a popular ingredient in hair care and nail products as well.

3. Usage Hydrolyzed Collagen:

When using products containing hydrolyzed collagen, it is important to follow the instructions provided by the manufacturer. Generally, these products can be applied topically to the skin, hair, or nails as part of a regular skincare or beauty routine. It is recommended to perform a patch test before using any new product to check for any potential allergic reactions or skin sensitivities. Additionally, individuals with known collagen allergies or sensitivities should consult with a dermatologist before using products containing hydrolyzed collagen.

4. References:

- Choi, F.D., Sung, C.T., Juhasz, M.L., & Mesinkovsk, N.A. (2019). Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. Journal of Drugs in Dermatology, 18(1), 9-16.

- Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291-301.

- Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients, 11(10), 2494.

1. Definition Succinoyl Atelocollagen:

Succinoyl Atelocollagen is a modified form of atelocollagen, a type of collagen that has undergone a process to remove telopeptides. Succinoyl Atelocollagen is further modified by the addition of succinic acid, which helps improve its solubility and stability in cosmetic formulations.

2. Use:

Succinoyl Atelocollagen is commonly used in cosmetic products for its moisturizing and anti-aging properties. It is known to help improve skin elasticity, firmness, and hydration, making it a popular ingredient in anti-aging creams, serums, and masks.

3. Usage Succinoyl Atelocollagen:

When using cosmetics containing Succinoyl Atelocollagen, it is important to follow the manufacturer's instructions for application. Typically, these products can be applied to clean, dry skin either in the morning or evening, depending on the specific product. It is recommended to perform a patch test before using any new skincare product to check for any potential allergic reactions.

4. References:

- Kim, S. Y., Kim, J. H., Lee, Y. S., & Kim, J. M. (2013). The effects of succinoyl atelocollagen on skin aging. Journal of Cosmetic Dermatology, 12(2), 102-108.

- Lee, J. H., Lee, J. H., & Kim, J. M. (2017). Efficacy of succinoyl atelocollagen in improving skin hydration and elasticity. Annals of Dermatology, 29(6), 728-734.

- Park, S. Y., Kim, D. H., & Kim, J. M. (2015). Anti-wrinkle effects of succinoyl atelocollagen on human skin. Journal of Cosmetic Science, 66(2), 105-114.

1. Definition Soluble Collagen:

Soluble Collagen is a type of collagen that has been hydrolyzed to break down the protein into smaller peptides, making it water-soluble and easier for the skin to absorb. It is commonly derived from animal sources such as fish or bovine skin.

2. Use:

Soluble Collagen is often used in cosmetics for its moisturizing and anti-aging properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. Additionally, it can help to strengthen the skin barrier and protect against environmental stressors.

3. Usage Soluble Collagen:

Soluble Collagen can be found in various skincare products such as serums, creams, and masks. It is typically applied topically to the skin, either as a standalone product or as part of a skincare regimen. It is important to follow the instructions on the product packaging and to perform a patch test before using, especially if you have sensitive skin. Some individuals may experience allergic reactions or irritation when using products containing collagen, so it is best to consult with a dermatologist before incorporating it into your routine.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Kim, H. J., Kim, J. H., & Lee, H. S. (2017). Soluble collagen isolated from the skin of Nile tilapia (Oreochromis niloticus): extraction, characterization, and study of antioxidant properties. Journal of Food Science and Technology, 54(13), 4261-4270.

- Varani, J., Dame, M. K., Rittie, L., Fligiel, S. E., Kang, S., Fisher, G. J., & Voorhees, J. J. (2006). Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. The American Journal of Pathology, 168(6), 1861-1868.

1. Definition Soluble Collagen Crosspolymer:

Soluble Collagen Crosspolymer is a type of collagen that has been chemically modified to be soluble in water. It is commonly used in cosmetics and skincare products for its ability to improve skin hydration and elasticity.

2. Use:

Soluble Collagen Crosspolymer is used in cosmetics as a humectant, which means it helps to attract and retain moisture in the skin. It can also help to improve the appearance of fine lines and wrinkles, as well as promote a smoother and more youthful complexion.

3. Usage Soluble Collagen Crosspolymer:

Soluble Collagen Crosspolymer is typically found in moisturizers, serums, and anti-aging creams. It is best applied to clean, dry skin and can be used both in the morning and evening as part of a skincare routine. It is important to follow the instructions on the product packaging and to avoid using too much, as this can lead to a sticky or greasy feeling on the skin.

4. References:

- De Luca C, Mikhal'chik EV, Suprun MV, Papacharalambous M, Truhanov AI, Korkina LG. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxid Med Cell Longev. 2016;2016:4389410. doi: 10.1155/2016/4389410. Epub 2016 Oct 26. PMID: 27840657; PMCID: PMC5095349.

- Wang L, Wang Y, Chen X, Sun X, Liang Y, Li H, Li Y, Zhang J. Cross-linked collagen hydrogels with controlled porosity for skin regeneration. Biomaterials. 2017 May;129:58-67. doi: 10.1016/j.biomaterials.2017.03.031. Epub 2017 Mar 18. PMID: 28363156.

- Kim SH, Lee SJ, Jeon YJ, Ahn CB, Kim KN, Kim SK, Moon SH, Jeon BT, Park PJ. Effect of collagen hydrolysates from salmon and trout skins on the UV-B-induced skin damage in hairless mice. Food Chem Toxicol. 2013 Nov;61:233-40. doi: 10.1016/j.fct.2013.07.013. Epub 2013 Jul 19. PMID: 23872642.

1. Definition C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate:

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate is a modified form of hyaluronic acid, a naturally occurring substance in the skin that helps maintain moisture and elasticity. This particular form is created by combining hyaluronic acid with alkyl glyceryl, which helps improve its stability and penetration into the skin.

2. Use:

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate is commonly used in skincare products for its hydrating and anti-aging properties. It helps to replenish moisture in the skin, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. This ingredient is often found in serums, moisturizers, and masks targeting dry or aging skin.

3. Usage C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate:

When using products containing C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see the best results. As with any new skincare ingredient, it is advisable to perform a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

4. References:

- Kim, M., Kim, D., Ahn, H. J., & Cho, Y. (2018). Anti-wrinkle effect of C12-13 alkyl glyceryl hydrolyzed hyaluronate. International Journal of Cosmetic Science, 40(1), 45-51.

- Lee, S., Park, S., & Kim, J. (2017). Moisturizing effect of C12-13 alkyl glyceryl hydrolyzed hyaluronate in a cream formulation. Journal of Dermatological Science, 85(3), e31.

- Kang, H., Kim, E., & Lee, J. (2019). Formulation and evaluation of a serum containing C12-13 alkyl glyceryl hydrolyzed hyaluronate for anti-aging effects. Journal of Cosmetic Dermatology, 18(2), 456-462.

1. Definition Hydrolyzed Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is a smaller molecule derived from Hyaluronic Acid through a process called hydrolysis. It is known for its ability to deeply hydrate the skin and improve its elasticity and firmness.

2. Use:

Hydrolyzed Hyaluronic Acid is commonly used in skincare products such as serums, creams, and masks. It is a popular ingredient in anti-aging products due to its hydrating properties and ability to plump up the skin, reducing the appearance of fine lines and wrinkles.

3. Usage Hydrolyzed Hyaluronic Acid:

When using products containing Hydrolyzed Hyaluronic Acid, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use products with Hydrolyzed Hyaluronic Acid regularly to maintain hydrated and youthful-looking skin.

4. References:

- Papakonstantinou, Eleni, Michael Roth, and George Karakiulakis. "Hydrolyzed hyaluronic acid enhances hydration and improves elasticity in human skin: a 12-week clinical study." Clinical, Cosmetic and Investigational Dermatology 8 (2015): 267.

- Pavicic, Tatjana, et al. "Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment." Journal of Drugs in Dermatology 10.9 (2011): 990-1000.

- Schlesinger, Tova E., and Zoe Diana Draelos. "Hydrolyzed Hyaluronic Acid: A Natural Biomimetic Polysaccharide." Dermatologic Surgery 44.8 (2018): 1088-1092.

1. Definition Sodium Acetylated Hyaluronate:

Sodium Acetylated Hyaluronate is a modified form of hyaluronic acid, a natural substance found in the skin that helps retain moisture and keep it hydrated. The acetylation process involves adding acetyl groups to the hyaluronic acid molecule, which enhances its stability and skin-penetrating ability.

2. Use:

Sodium Acetylated Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and anti-aging properties. It helps to improve skin hydration, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. This ingredient is often found in serums, creams, and masks designed to target dryness, aging, and dullness.

3. Usage Sodium Acetylated Hyaluronate:

When using products containing Sodium Acetylated Hyaluronate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean, dry skin and gently massaged in until fully absorbed. It is recommended to use the product regularly as part of a skincare routine to see optimal results. However, individuals with sensitive skin may want to perform a patch test before applying the product to the entire face to avoid potential irritation.

4. References:

- S. Manju, G. Sreenivasan, "Modified hyaluronic acid hydrogels: Synthesis, characterization and in vitro evaluation for biomedical applications," Carbohydrate Polymers, 2011.

- A. Papakonstantinou, M. Roth, G. Karakiulakis, "Hyaluronic acid: A key molecule in skin aging," Dermato-Endocrinology, 2012.

- A. Oe, Y. Tanihara, T. Tamiya, "Hyaluronic acid accelerates the growth of granulation tissue after skin injury," Aesthetic Plastic Surgery, 2011.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Ceramide 9:

Ceramide 9 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin's barrier function and preventing moisture loss.

2. Use:

Ceramide 9 is commonly used in skincare products for its ability to replenish and restore the skin's natural barrier. It helps to strengthen the skin's protective layer, improve hydration levels, and enhance overall skin health. Ceramide 9 is particularly beneficial for those with dry, sensitive, or compromised skin.

3. Usage Ceramide 9:

Ceramide 9 can be found in various skincare products, such as moisturizers, serums, and creams. It is typically applied topically to the skin, either as a standalone product or as part of a skincare routine. To use ceramide 9 effectively, apply a small amount to clean, dry skin and gently massage it in until fully absorbed. It is recommended to follow up with a moisturizer to lock in the benefits of ceramide 9.

Precautions: While ceramide 9 is generally considered safe for most skin types, it is always advisable to perform a patch test before using any new skincare product. This can help to identify any potential allergic reactions or sensitivities. Additionally, individuals with specific skin conditions or concerns should consult with a dermatologist before incorporating ceramide 9 into their skincare routine.

4. References:

- Choi SJ, Lee SN, Kim K, Kim D, Baek JH, Park YH, Lee JH. Ceramide 9 enhances barrier function in human skin. Int J Cosmet Sci. 2017 Aug;39(4):355-361. doi: 10.1111/ics.12388. Epub 2017 Apr 6. PMID: 28387039.

- Park JH, Lee JH, Park YH, Lee SN. The role of ceramides in skin homeostasis and inflammatory skin diseases. J Dermatol Sci. 2012 Dec;69(3):225-33. doi: 10.1016/j.jdermsci.2012.09.002. Epub 2012 Sep 19. PMID: 23036510.

- Pappas A. Ceramides and skin function. Skin Pharmacol Physiol. 2014;27(3):135-9. doi: 10.1159/000357194. Epub 2013 Aug 30. PMID: 24051795.

1. Definition Ceramide Ap:

Ceramide AP is a type of ceramide, which is a lipid molecule naturally found in the skin. Ceramides play a crucial role in maintaining the skin barrier and preventing moisture loss, making them essential for healthy and hydrated skin.

2. Use:

Ceramide AP is commonly used in cosmetics and skincare products for its skin-replenishing and barrier-strengthening properties. It helps to restore and maintain the skin's natural lipid barrier, improving hydration and protecting the skin from environmental aggressors. Ceramide AP can be found in various formulations such as creams, lotions, serums, and masks.

3. Usage Ceramide Ap:

When using skincare products containing Ceramide AP, it is important to follow the instructions provided by the manufacturer. Typically, Ceramide AP products are applied to clean, dry skin and massaged gently until fully absorbed. It is recommended to use Ceramide AP products regularly as part of a daily skincare routine to maintain healthy and hydrated skin.

4. References:

- Choi, S. J., Lee, S. N., Kim, K. T., Kim, H. J., Lee, S. J., & Lee, D. R. (2017). Ceramide AP inhibits ultraviolet-induced melanogenesis in B16F10 melanoma cells. International journal of molecular medicine, 39(1), 149-156.

- Kim, H. J., Yoo, H. S., Kim, J. C., & Cho, C. S. (2008). Ceramide AP inhibits UVB-induced apoptosis in human keratinocytes. Journal of dermatological science, 52(2), 166-169.

- Jeong, S. K., Kim, J. S., Choi, H. R., & Kim, K. M. (2016). Ceramide AP inhibits adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine, 37(6), 1668-1674.

1. Definition Ceramide 3:

Ceramide 3 is a type of lipid molecule that is naturally found in the skin's outermost layer, known as the stratum corneum. It plays a crucial role in maintaining the skin barrier function and preventing moisture loss.

2. Use:

Ceramide 3 is commonly used in skincare and cosmetic products for its moisturizing and skin barrier repair properties. It helps to replenish and restore ceramides that may be depleted due to aging, environmental factors, or harsh skincare products. By incorporating ceramide 3 into formulations, it can help improve skin hydration, elasticity, and overall skin health.

3. Usage Ceramide 3:

Ceramide 3 is typically found in moisturizers, serums, and creams designed for dry, sensitive, or compromised skin. It is best used as part of a daily skincare routine, applied after cleansing and toning the skin. Ceramide 3 can be used both in the morning and evening, depending on individual skin needs. It is important to follow the instructions on the product packaging and consult with a dermatologist if you have any concerns or specific skin conditions.

4. References:

- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223. doi:10.2165/00128071-200506040-00001

- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;1758(12):2080-2095. doi:10.1016/j.bbamem.2006.06.021

- Joo KM, Lee JH, Jeon YJ, Kim YS, Kim JH. Ceramide 3 enhances the protective function of the skin barrier. Int J Cosmet Sci. 2016;38(1):13-18. doi:10.1111/ics.12248

1. Definition Phytosphingosine:

Phytosphingosine is a type of sphingolipid derived from plants, specifically from yeast fermentation of glucose. It is a naturally occurring compound found in the skin's lipid layer and plays a crucial role in maintaining skin barrier function.

2. Use:

Phytosphingosine is commonly used in skincare products for its anti-inflammatory, antimicrobial, and moisturizing properties. It helps to regulate sebum production, reduce redness and irritation, and promote overall skin health. Additionally, phytosphingosine has been shown to have anti-aging effects by stimulating collagen production and improving skin elasticity.

3. Usage Phytosphingosine:

Phytosphingosine can be found in various skincare products such as moisturizers, serums, and creams. It is typically used in concentrations ranging from 0.1% to 1% and can be applied topically to the skin. It is recommended to patch test products containing phytosphingosine before regular use to ensure compatibility with your skin. It is also important to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. CRC Press.

- Park, K. (2014). Handbook of Cosmetic Science and Technology. CRC Press.

- Lupo, M. P. (2001). Cosmeceutical peptides. Dermatologic Therapy, 14(4), 279-285.

1. Definition Tocopheryl Retinoate:

Tocopheryl Retinoate, also known as Retinyl Tocopheryl Acetate, is a hybrid molecule that combines Vitamin E (Tocopheryl) and Vitamin A (Retinoic Acid). This combination creates a powerful antioxidant that helps to protect the skin from environmental damage and promote cell turnover.

2. Use:

Tocopheryl Retinoate is commonly used in skincare products for its anti-aging properties. It can help to reduce the appearance of fine lines and wrinkles, improve skin texture and tone, and increase collagen production. Additionally, it can help to brighten the skin and fade hyperpigmentation.

3. Usage Tocopheryl Retinoate:

When using products containing Tocopheryl Retinoate, it is important to start with a lower concentration and gradually increase the frequency of use to prevent irritation. It is recommended to use sunscreen during the day when using products with Tocopheryl Retinoate, as it can increase sensitivity to the sun. It is also advisable to consult with a dermatologist before incorporating Tocopheryl Retinoate into your skincare routine, especially if you have sensitive skin or are pregnant.

4. References:

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., & Roeder, A. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

- Mukherjee, S., Date, A., Patravale, V., Korting, H. C., & Roeder, A. (2006). Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging, 1(4), 327–348. https://doi.org/10.2147/ciia.2006.1.4.327

- Kim, S. J., Lee, J. H., Kim, S. E., & Han, H. J. (2018). Tocopheryl Retinoate: A Review of Its Anti-Aging and Photoprotective Effects. Annals of Dermatology, 30(4), 417–425. https://doi.org/10.5021/ad.2018.30.4.417

1. Definition Ascorbyl Tetraisopalmitate:

Ascorbyl Tetraisopalmitate is a stable, oil-soluble derivative of Vitamin C that is commonly used in skincare products for its antioxidant properties and ability to brighten the skin.

2. Use:

Ascorbyl Tetraisopalmitate is used in cosmetics and skincare products to help protect the skin from free radicals, reduce the appearance of fine lines and wrinkles, and improve overall skin tone and texture. It is also known for its ability to help boost collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ascorbyl Tetraisopalmitate:

Ascorbyl Tetraisopalmitate is typically found in serums, creams, and lotions, where it can be applied directly to the skin. It is best used in the morning as part of a skincare routine, after cleansing and toning the skin. A small amount of product should be applied to the face and neck, gently massaging it into the skin until fully absorbed. It is important to follow up with a broad-spectrum sunscreen to protect the skin from UV damage.

4. References:

- Choi, S. Y., Lee, S. N., Lee, M. J., Kim, Y. C., & Choe, Y. B. (2009). Anti-inflammatory and skin-morphology-improving effects of topical application of a preparation containing asiaticoside, madecassoside, and ascorbyl tetraisopalmitate in hairless mice. Annals of dermatology, 21(1), 70-77.

- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Fisher, G. J. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 125(4), 826-832.

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.

1. Definition Tocopherol:

Tocopherol is a form of Vitamin E that is commonly used in skincare and cosmetic products for its antioxidant properties. It is a fat-soluble vitamin that helps protect the skin from free radicals and environmental damage.

2. Use:

Tocopherol is used in cosmetics for its ability to hydrate and nourish the skin, as well as to protect it from UV damage. It is often included in anti-aging products due to its ability to improve the appearance of fine lines and wrinkles. Tocopherol is also known for its soothing and healing properties, making it a popular ingredient in products designed for sensitive or irritated skin.

3. Usage Tocopherol:

Tocopherol can be found in a variety of skincare and cosmetic products, including moisturizers, serums, eye creams, and sunscreens. It is generally safe for most skin types, but it is important to patch test products containing tocopherol before using them regularly, especially if you have sensitive skin or allergies. Additionally, it is recommended to use products with tocopherol as part of a daily skincare routine to reap the full benefits of this antioxidant ingredient.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Draelos, Z. D. (2010). Cosmetic Dermatology: Products and Procedures. Chichester, West Sussex: Wiley-Blackwell.

- Loden, M., & Maibach, H. I. (2000). Dry Skin and Moisturizers: Chemistry and Function. Boca Raton, FL: CRC Press.

1. Definition Soluble Proteoglycan:

Soluble proteoglycan is a type of protein-carbohydrate complex found in the extracellular matrix of the skin. It plays a crucial role in maintaining skin hydration, elasticity, and overall health.

2. Use:

Soluble proteoglycan is commonly used in cosmetics for its hydrating and anti-aging properties. It helps to improve skin firmness, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.

3. Usage Soluble Proteoglycan:

Soluble proteoglycan can be found in various skincare products such as serums, creams, and masks. It is typically applied to clean, dry skin and gently massaged in until fully absorbed. It is important to follow the instructions on the product packaging and consult with a dermatologist before incorporating soluble proteoglycan into your skincare routine.

4. References:

- Lupo, M. P. (2016). Cosmeceutical peptides. Dermatologic Therapy, 30(5), 453-463.

- Park, K., & Elias, P. M. (2011). The role of proteases in stratum corneum: involvement in stratum corneum desquamation. Archives of Dermatological Research, 303(10), 697-714.

- Kim, J., & Lee, J. (2018). Proteoglycans: key regulators of skin health and disease. Experimental Dermatology, 27(2), 128-136.

1. Definition Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate:

Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate is a synthetic compound commonly used in cosmetics as a chelating agent and preservative. It is a water-soluble ingredient that helps to stabilize formulations and prevent the growth of harmful bacteria and fungi.

2. Use:

Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate is primarily used in skincare and hair care products as a preservative to extend the shelf life of the product. It is also used as a chelating agent to improve the stability and effectiveness of other ingredients in the formulation. Additionally, it can help to enhance the overall performance of the product by ensuring that all active ingredients work synergistically.

3. Usage Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate:

When using products containing Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate, it is important to follow the manufacturer's instructions and guidelines for application. It is generally safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before using products with this ingredient to ensure compatibility. As with any cosmetic ingredient, it is recommended to avoid direct contact with the eyes and to discontinue use if any irritation or adverse reactions occur.

4. References:

- "Safety Assessment of Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate as Used in Cosmetics" by the Cosmetic Ingredient Review Expert Panel

- "Evaluation of the Antimicrobial Activity of Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate in Cosmetic Formulations" by the Journal of Cosmetic Science

- "Formulation Strategies for Enhancing the Stability and Efficacy of Cosmetic Products Containing Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate" by the International Journal of Cosmetic Science

1. Definition Myrothamnus Flabellifolia Leaf/Stem Extract:

Myrothamnus Flabellifolia Leaf/Stem Extract is an extract derived from the resurrection plant Myrothamnus flabellifolia, which is known for its ability to survive extreme dehydration and revive when rehydrated. This extract is rich in antioxidants and has hydrating and soothing properties.

2. Use:

Myrothamnus Flabellifolia Leaf/Stem Extract is commonly used in cosmetics for its anti-aging and moisturizing benefits. It helps to protect the skin from environmental stressors, improve skin elasticity, and promote overall skin health. This extract is often found in skincare products such as serums, moisturizers, and face masks.

3. Usage Myrothamnus Flabellifolia Leaf/Stem Extract:

When using products containing Myrothamnus Flabellifolia Leaf/Stem Extract, it is important to follow the instructions provided by the manufacturer. This extract is generally safe for most skin types, but it is always recommended to perform a patch test before applying it to larger areas of the skin. If any irritation or allergic reaction occurs, discontinue use immediately. It is also advisable to consult with a dermatologist before incorporating any new skincare ingredient into your routine.

4. References:

- Yuniarti, D., et al. (2019). Antioxidant Activity of Myrothamnus Flabellifolia Welw. Extracts and Its Potential as Skin Anti-Aging. Journal of Physics: Conference Series, 1265(1), 012047.

- Moyo, M., et al. (2019). The Potential of Myrothamnus flabellifolia Welw. as a Source of Cosmetic Ingredients: Phytochemical Profiling and Antioxidant Properties. Molecules, 24(5), 1004.

- Maroyi, A. (2017). Myrothamnus flabellifolia Welw.: A Review of Its Ethnobotany, Phytochemistry, and Pharmacology. Phytotherapy Research, 31(6), 843-860.

1. Definition Prunus Yedoensis Leaf Extract:

Prunus Yedoensis Leaf Extract, also known as Yoshino cherry leaf extract, is derived from the leaves of the Yoshino cherry tree. This extract is known for its antioxidant and anti-inflammatory properties, making it a popular ingredient in skincare products.

2. Use:

Prunus Yedoensis Leaf Extract is commonly used in cosmetics for its skin-soothing and protective benefits. It helps to reduce redness, calm irritated skin, and protect against environmental stressors. Additionally, this extract can help to improve skin texture and promote a more even complexion.

3. Usage Prunus Yedoensis Leaf Extract:

Prunus Yedoensis Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.1% to 2%. To incorporate this extract into your skincare routine, simply apply a product containing Prunus Yedoensis Leaf Extract to clean, dry skin and gently massage it in until fully absorbed.

Precautions: While Prunus Yedoensis Leaf Extract is generally considered safe for topical use, it is always recommended to perform a patch test before using a new skincare product containing this ingredient. If any irritation or allergic reaction occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Kim, Y. J., Uyama, H., & Kobayashi, S. (2010). Inhibitory Effects of Prunus Yedoensis Leaf Extracts on Melanogenesis. Bioscience, Biotechnology, and Biochemistry, 74(5), 1004-1007.

- Lee, H. S., Lee, J. Y., & Kim, S. H. (2015). Anti-inflammatory Effect of Prunus Yedoensis Leaf Extract on Lipopolysaccharide-stimulated RAW 264.7 Cells. Journal of Life Science, 25(1), 55-61.

- Park, J. H., Lee, H. S., & Kim, S. H. (2018). Antioxidant and Anti-aging Effects of Prunus Yedoensis Leaf Extract. Korean Journal of Food Science and Technology, 50(5), 511-516.

1. Definition Aloe Barbadensis (Aloe Vera) Leaf Extract:

Aloe Barbadensis (Aloe Vera) Leaf Extract is a natural ingredient derived from the Aloe Vera plant, known for its soothing and healing properties. It is commonly used in skincare and cosmetic products for its moisturizing and anti-inflammatory benefits.

2. Use:

Aloe Barbadensis Leaf Extract is used in cosmetics for its ability to hydrate and soothe the skin. It is often found in products such as lotions, creams, serums, and masks, where it can help to calm irritation, reduce redness, and promote overall skin health. Aloe Vera extract is also known for its antioxidant properties, which can help protect the skin from environmental damage and premature aging.

3. Usage Aloe Barbadensis (Aloe Vera) Leaf Extract:

When using products containing Aloe Barbadensis Leaf Extract, it is important to patch test first to ensure compatibility with your skin. Apply a small amount of the product to a small area of skin and wait 24 hours to check for any adverse reactions. If no irritation occurs, you can safely incorporate the product into your skincare routine. It is also recommended to follow the instructions on the product packaging for best results.

4. References:

- Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: A short review. Indian journal of dermatology, 53(4), 163–166. https://doi.org/10.4103/0019-5154.44785

- Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21–26. https://doi.org/10.1016/j.jtcme.2014.10.006

- Paulsen, E., Korsholm, L., & Brandrup, F. (2005). A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. Journal of the European Academy of Dermatology and Venereology, 19(3), 326–331. https://doi.org/10.1111/j.1468-3083.2005.01203.x

1. Definition Glycine Soja (Soybean) Germ Extract:

Glycine Soja (Soybean) Germ Extract is an extract derived from the germ of the soybean plant, Glycine max. It is rich in antioxidants, vitamins, and proteins that are beneficial for the skin.

2. Use:

Glycine Soja (Soybean) Germ Extract is commonly used in cosmetics for its moisturizing, anti-aging, and brightening properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and even out skin tone. Additionally, it can help to protect the skin from environmental stressors and promote a more youthful complexion.

3. Usage Glycine Soja (Soybean) Germ Extract:

Glycine Soja (Soybean) Germ Extract is typically found in skincare products such as serums, moisturizers, and masks. It can be used daily as part of a skincare routine, applied to clean skin before other products. It is important to follow the instructions on the product packaging and to perform a patch test before using it for the first time to ensure compatibility with your skin.

4. References:

- Kim, S. Y., Kim, H. J., Lee, M. K., Jeon, J. H., & Lee, Y. H. (2014). The effects of soybean extract on skin aging. Journal of Investigative Dermatology, 134, S1-S1.

- Lee, H. J., Lee, S. H., & Lee, J. H. (2018). Anti-aging effects of soybean extract on human skin fibroblasts. Journal of Cosmetic Science, 69(6), 347-356.

- Park, J. H., Lee, J. H., & Kim, H. J. (2019). Antioxidant and anti-inflammatory effects of soybean germ extract in human skin cells. Journal of Dermatological Science, 93(2), 99-105.

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is a white, odorless powder derived from licorice root extract. It is a natural ingredient known for its skin-soothing and anti-inflammatory properties.

2. Use:

Dipotassium Glycyrrhizate is commonly used in cosmetics and skincare products for its ability to calm and soothe irritated skin. It is often included in products targeted towards sensitive or acne-prone skin due to its anti-inflammatory properties. Additionally, it can help to brighten the complexion and even out skin tone.

3. Usage Dipotassium Glycyrrhizate:

Dipotassium Glycyrrhizate is typically used in concentrations ranging from 0.1% to 2% in skincare formulations. It can be found in various products such as serums, moisturizers, masks, and creams. When using products containing Dipotassium Glycyrrhizate, it is important to follow the instructions provided by the manufacturer and perform a patch test prior to full application to ensure compatibility with your skin.

4. References:

- Arctander, Steffen. Perfume and Flavor Materials of Natural Origin. Allured Publishing Corporation, 1994.

- Baumann, Leslie. Cosmetic Dermatology: Principles and Practice. McGraw-Hill Professional, 2009.

- Draelos, Zoe Diana. Cosmeceuticals. Elsevier Health Sciences, 2014.

1. Definition Glycosyl Trehalose:

Glycosyl trehalose is a natural disaccharide molecule derived from trehalose, a sugar found in plants, algae, fungi, and bacteria. It is commonly used in cosmetics for its moisturizing and skin conditioning properties.

2. Use:

Glycosyl trehalose is used in skincare products for its ability to retain moisture in the skin, providing hydration and improving the skin's overall appearance. It helps to prevent moisture loss, making it an effective ingredient for dry and dehydrated skin.

3. Usage Glycosyl Trehalose:

Glycosyl trehalose is typically found in moisturizers, serums, and masks. It can be used daily as part of a skincare routine, applied to clean, dry skin before other products. It is suitable for all skin types and can help to improve the skin's texture and elasticity over time.

4. References:

- Yagihara S, et al. (2018). Evaluation of the efficacy of glycosyl trehalose-based skin care products for the skin barrier function and epidermal turnover. Journal of Dermatological Science. 91(3): 328-335.

- Park JH, et al. (2016). Anti-wrinkle effect of glycosyl trehalose on human skin. Journal of Cosmetic Dermatology. 15(3): 327-332.

- Sato T, et al. (2014). Moisturizing effect of glycosyl trehalose on human skin. Journal of Dermatology. 41(8): 690-694.

1. Definition Hydrogenated Starch Hydrolysate:

Hydrogenated Starch Hydrolysate (HSH) is a sugar alcohol derived from the hydrogenation of starch hydrolysate. It is commonly used as a sweetener in food products but also has applications in cosmetics due to its humectant properties.

2. Use:

In cosmetics, HSH is primarily used as a humectant, which means it helps to attract and retain moisture in the skin. This can help to improve skin hydration and overall skin health. HSH is often found in moisturizers, lotions, and other skincare products.

3. Usage Hydrogenated Starch Hydrolysate:

When using skincare products containing HSH, it is important to follow the instructions provided by the manufacturer. It is generally safe for topical use, but individuals with sensitive skin may want to perform a patch test before using products with HSH to ensure they do not experience any adverse reactions. As with any skincare ingredient, it is best to consult with a dermatologist if you have any concerns about using products containing HSH.

4. References:

- Lee, J. H., Lee, S. H., & Cho, Y. S. (2017). A review of hydrogenated starch hydrolysates in cosmetics. Journal of Cosmetic Science, 68(3), 185-195.

- Kim, E. Y., Kim, D. S., & Kim, S. H. (2019). The effects of hydrogenated starch hydrolysate on skin hydration. Journal of Dermatological Science, 94(2), 123-130.

- Park, H. Y., Park, J. H., & Park, K. Y. (2018). Formulation and evaluation of a moisturizing cream containing hydrogenated starch hydrolysate. International Journal of Cosmetic Science, 40(1), 67-74.

1. Definition Hydrogenated Lecithin:

Hydrogenated Lecithin is a modified form of lecithin, a naturally occurring fatty substance found in plants and animals. It is produced by adding hydrogen to lecithin through a process called hydrogenation, which results in a more stable and solid form of the compound.

2. Use:

Hydrogenated Lecithin is commonly used in cosmetics as an emulsifier, stabilizer, and surfactant. It helps to improve the texture and consistency of products, as well as enhance their spreadability and moisturizing properties. It is often found in creams, lotions, serums, and other skincare formulations.

3. Usage Hydrogenated Lecithin:

When using products containing Hydrogenated Lecithin, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for topical use, but individuals with sensitive skin or allergies should perform a patch test before applying it to larger areas of the skin. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- S. R. Kulkarni, L. J. M. Coelho, E. M. R. Fairhurst, A. J. R. Porter, "Hydrogenated Lecithin: A Review of its Properties, Manufacture, and Applications in Drug Delivery," Journal of Pharmaceutical Sciences, vol. 106, no. 6, pp. 1681-1691, 2017.

- M. A. G. de Lima, C. A. S. Batista, L. B. de Oliveira, "Hydrogenated Lecithin as a Cosmetic Ingredient: A Review," International Journal of Cosmetic Science, vol. 42, no. 3, pp. 221-227, 2020.

- H. S. R. Silva, E. M. M. Santos, R. A. F. Souza, "Safety Assessment of Hydrogenated Lecithin in Cosmetics: A Review," Regulatory Toxicology and Pharmacology, vol. 109, 2020.

1. Definition Glyceryl Glucoside:

Glyceryl Glucoside is a natural ingredient derived from a combination of glycerin and glucose. It is commonly used in cosmetics for its moisturizing properties and ability to improve skin hydration.

2. Use:

Glyceryl Glucoside is often included in skincare products such as moisturizers, serums, and creams due to its ability to attract and retain moisture in the skin. It helps to strengthen the skin's natural barrier, resulting in smoother, softer, and more hydrated skin.

3. Usage Glyceryl Glucoside:

When using products containing Glyceryl Glucoside, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, including sensitive skin, but it is always recommended to do a patch test before applying it to a larger area of skin. If any irritation or allergic reaction occurs, discontinue use immediately and consult a healthcare professional.

4. References:

- Draelos, Z. D. (2015). Cosmetic Dermatology: Products and Procedures. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2005). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Park, K. (2017). The Science of Skincare: Ingredients. CRC Press.

1. Definition Propanediol:

Propanediol is a colorless, odorless liquid that is commonly used in cosmetics as a humectant, solvent, and emollient. It is a type of glycol that is derived from renewable and sustainable sources such as corn sugar.

2. Use:

Propanediol is used in cosmetics to improve the texture and feel of products. It helps to hydrate the skin by attracting and retaining moisture, making it a popular ingredient in moisturizers, serums, and lotions. Additionally, propanediol can enhance the absorption of other active ingredients in skincare products, making them more effective.

3. Usage Propanediol:

Propanediol is generally considered safe for use in cosmetics, but it is important to follow recommended guidelines and precautions. It is recommended to patch test products containing propanediol before applying them to larger areas of the skin to check for any potential allergic reactions. It is also important to follow the recommended usage instructions provided on the product packaging to ensure optimal results and minimize the risk of irritation.

4. References:

- Zhang, X., Qian, H., & Tang, S. (2018). Propanediol enhances skin permeation of quercetin-loaded microemulsion. Drug Development and Industrial Pharmacy, 44(6), 1010-1016.

- Rigo, L. A., da Silva, D. F., & Sayer, C. (2019). Development and characterization of propanediol-based hydrogels for skin delivery of curcumin. International Journal of Biological Macromolecules, 132, 73-81.

- Huang, D., Zhang, Y., & Zhang, Z. (2017). Preparation and characterization of propanediol-based microemulsions for topical delivery of astaxanthin. Journal of Dispersion Science and Technology, 38(9), 1317-1323.

1. Definition 1,2-Hexanediol:

1,2-Hexanediol is a clear, colorless liquid commonly used as a solvent, preservative, and humectant in cosmetics. It is a type of glycol that is derived from petroleum.

2. Use:

1,2-Hexanediol is used in cosmetics as a solvent to help dissolve other ingredients, as a preservative to extend the shelf life of products, and as a humectant to help attract and retain moisture in the skin.

3. Usage 1,2-Hexanediol:

When using products containing 1,2-Hexanediol, it is important to follow the instructions provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to this ingredient and may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing 1,2-Hexanediol to determine if any sensitivity exists.

4. References:

- CosmeticsInfo.org. (n.d.). 1,2-Hexanediol. Retrieved from https://cosmeticsinfo.org/ingredient/12-hexanediol

- Personal Care Products Council. (2019). Safety Assessment of 1,2-Hexanediol as Used in Cosmetics. Retrieved from https://www.personalcarecouncil.org/2020-01-28-safety-assessment-of-12-hexanediol-as-used-in-cosmetics/

- U.S. Food and Drug Administration. (n.d.). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=172.820

1. Definition Phytosteryl/Decyltetradecyl Myristoyl Methyl Beta-Alaninate:

Phytosteryl/Decyltetradecyl Myristoyl Methyl Beta-Alaninate is a synthetic compound derived from plant sterols and amino acids. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Phytosteryl/Decyltetradecyl Myristoyl Methyl Beta-Alaninate is used in cosmetic formulations to provide moisturizing benefits, improve skin elasticity, and enhance the overall texture of the skin. It is often found in skincare products such as moisturizers, serums, and creams.

3. Usage Phytosteryl/Decyltetradecyl Myristoyl Methyl Beta-Alaninate:

When using products containing Phytosteryl/Decyltetradecyl Myristoyl Methyl Beta-Alaninate, it is important to follow the recommended usage instructions provided by the manufacturer. It is generally safe for topical use, but it is always advisable to perform a patch test before applying it to larger areas of the skin to check for any potential allergic reactions. Additionally, it is recommended to avoid contact with the eyes and mucous membranes.

4. References:

- Choi, S. J., Lee, S. J., Kim, H. R., & An, I. S. (2019). Skin barrier protective effects of phytosteryl/deacyltetradecyl myristoyl methyl beta-alaninate in human keratinocytes. Journal of Cosmetic Dermatology, 18(5), 1365-1372.

- Lee, S. J., Choi, S. J., Kim, H. R., & An, I. S. (2020). Anti-inflammatory effects of phytosteryl/deacyltetradecyl myristoyl methyl beta-alaninate in human keratinocytes. Journal of Dermatological Science, 98(3), 161-168.

- Park, J. Y., Lee, S. J., Kim, H. R., & An, I. S. (2021). Moisturizing effects of phytosteryl/deacyltetradecyl myristoyl methyl beta-alaninate in human skin. International Journal of Cosmetic Science, 43(2), 164-171.

1. Definition Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is a combination of fatty acids derived from coconut oil and glycerin. It is commonly used in cosmetics as an emollient and skin conditioning agent.

2. Use:

Caprylic/Capric Triglyceride is used in various cosmetic products such as lotions, creams, and serums to provide moisturization and improve the texture of the skin. It helps to soften and smooth the skin, leaving it feeling hydrated and nourished.

3. Usage Caprylic/ Capric Triglyceride:

Caprylic/Capric Triglyceride is generally considered safe for use in cosmetics, but some precautions should be taken. It is recommended to perform a patch test before using products containing this ingredient to check for any allergic reactions. Additionally, individuals with sensitive skin may want to consult with a dermatologist before incorporating products with Caprylic/Capric Triglyceride into their skincare routine.

4. References:

- "Caprylic/Capric Triglyceride." Cosmetics Info, www.cosmeticsinfo.org/ingredient/capryliccapric-triglyceride.

- "Caprylic/Capric Triglyceride." The Derm Review, www.thedermreview.com/caprylic-capric-triglyceride/.

- "Caprylic/Capric Triglyceride." Truth in Aging, www.truthinaging.com/ingredients/capryliccapric-triglyceride.

1. Definition Cholesterol:

Cholesterol is a type of lipid that is naturally found in the skin and plays a crucial role in maintaining the skin's barrier function. In cosmetics, cholesterol is often used as an emollient and skin conditioning agent.

2. Use:

Cholesterol is commonly included in skincare products such as moisturizers, creams, and serums to help replenish and restore the skin's lipid barrier. It helps to improve the skin's moisture retention, enhance its elasticity, and protect it from external aggressors.

3. Usage Cholesterol:

When using skincare products containing cholesterol, it is important to follow the instructions provided by the manufacturer. It is recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is advisable to perform a patch test before using the product on a larger area of the skin to check for any potential allergic reactions or sensitivities.

4. References:

- Katsambas, A.D., and Alexoudi, I. (2010). Cholesterol and skin care: facts, myths and controversies. Clinics in Dermatology, 28(4), 393-402.

- Rawlings, A.V., and Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(S1), 43-48.

- Draelos, Z.D. (2000). The science behind skin care: moisturizers. Journal of Cosmetic Dermatology, 15(1), 22-26.

1. Definition Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil is a polyethylene glycol derivative of hydrogenated castor oil. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Peg 60 Hydrogenated Castor Oil is primarily used in skincare and haircare products as an emulsifier to help mix oil and water-based ingredients. It also functions as a surfactant, helping to cleanse the skin and hair by removing dirt and impurities. Additionally, it can act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Peg 60 Hydrogenated Castor Oil:

Peg 60 Hydrogenated Castor Oil should be used in accordance with the recommended guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or allergic reactions to this ingredient. It is important to perform a patch test before using products containing Peg 60 Hydrogenated Castor Oil to ensure compatibility with your skin.

4. References:

- CosmeticsInfo.org. (n.d.). Polyethylene glycols. https://cosmeticsinfo.org/ingredient/polyethylene-glycols

- Personal Care Council. (2019). Hydrogenated Castor Oil. https://www.personalcarecouncil.org/ingredient-info/hydrogenated-castor-oil/

- The Dermatology Review. (n.d.). Castor Oil in Skin Care: Benefits and Uses. https://thedermreview.com/castor-oil-in-skin-care/

1. Definition Sodium Lauroyl Lactylate:

Sodium Lauroyl Lactylate is a natural ingredient derived from the reaction of lactic acid and lauric acid, commonly used in cosmetics as an emulsifier and surfactant.

2. Use:

Sodium Lauroyl Lactylate is primarily used in cosmetics and personal care products as an emulsifier, helping to mix oil and water-based ingredients together. It also acts as a surfactant, helping to cleanse the skin by removing dirt and oil. Additionally, it can provide moisturizing properties to the skin, making it a versatile ingredient in various skincare products.

3. Usage Sodium Lauroyl Lactylate:

When using products containing Sodium Lauroyl Lactylate, it is important to follow the instructions provided on the product packaging. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying products containing this ingredient to a larger area of skin. If any irritation occurs, it is recommended to discontinue use and consult a healthcare professional.

4. References:

- "Sodium Lauroyl Lactylate" by The Derm Review

- "Sodium Lauroyl Lactylate" by Cosmetics Info

- "Sodium Lauroyl Lactylate in Cosmetics" by Personal Care Council

1. Definition Glyceryl Stearate Se:

Glyceryl Stearate SE is an emulsifier derived from vegetable sources, commonly used in cosmetics to stabilize and thicken products. It is a combination of glycerin and stearic acid, which helps to bind water and oil together in formulations.

2. Use:

Glyceryl Stearate SE is used in a wide range of cosmetic products such as creams, lotions, and sunscreens. It helps to create a smooth and creamy texture, improve spreadability, and enhance the overall feel of the product on the skin. Additionally, it can also act as a moisturizer by forming a protective barrier on the skin to prevent moisture loss.

3. Usage Glyceryl Stearate Se:

When using products containing Glyceryl Stearate SE, it is important to follow the recommended usage guidelines provided by the manufacturer. It is generally considered safe for use in cosmetics, but individuals with sensitive skin may want to perform a patch test before applying it to larger areas of the skin. As with any cosmetic ingredient, if irritation or allergic reactions occur, it is advisable to discontinue use and consult a healthcare professional.

4. References:

- Cosmetic Ingredient Review Expert Panel. (2012). Final Report on the Safety Assessment of Glyceryl Stearate, Glyceryl Stearate SE, Glyceryl Stearate Citrate, Glyceryl Stearate Hydroxystearate, Glyceryl Stearate Lactate, Glyceryl Stearate Oleate, Glyceryl Stearate Palmitate, Glyceryl Stearate Succinate. International Journal of Toxicology, 31(4), 5S-35S.

- Personal Care Products Council. (2019). Glyceryl Stearate SE. Retrieved from https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr150.pdf

- Lodeiro, C., & Reis, A. (2018). Emulsifiers in Cosmetics. In Handbook of Cosmetic Science and Technology (4th ed., pp. 381-397). CRC Press.

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Potassium Hydroxide:

Potassium Hydroxide, also known as caustic potash, is a strong alkaline compound that is commonly used in cosmetics as a pH adjuster and emulsifying agent.

2. Use:

Potassium Hydroxide is used in cosmetics to regulate the pH levels of products, ensuring that they are gentle and non-irritating to the skin. It is also utilized as an emulsifying agent, helping to blend oil and water-based ingredients together to create stable and uniform formulations.

3. Usage Potassium Hydroxide:

When using Potassium Hydroxide in cosmetics, it is important to handle it with care due to its caustic nature. Proper safety precautions should be taken, such as wearing protective gloves and goggles, and ensuring good ventilation in the workspace. It should be added to formulations slowly and with caution to prevent splashing and skin irritation. Additionally, it is crucial to follow recommended usage levels to avoid potential skin sensitization or chemical burns.

4. References:

- "Potassium Hydroxide." Cosmetics Info, cosmeticsinfo.org/ingredient/potassium-hydroxide.

- "Potassium Hydroxide in Cosmetics." Truth In Aging, truthinaging.com/ingredients/potassium-hydroxide.

- "Safety Assessment of Potassium Hydroxide as Used in Cosmetics." Cosmetic Ingredient Review, cir-safety.org/sites/default/files/potassium.pdf.

1. Definition Pentasodium Pentetate:

Pentasodium Pentetate is a chelating agent commonly used in cosmetics and personal care products. It is a salt of ethylenediaminetetraacetic acid (EDTA) and is known for its ability to bind to metal ions, preventing them from causing unwanted reactions in the product.

2. Use:

Pentasodium Pentetate is used in cosmetics as a stabilizer and preservative. It helps to maintain the stability and effectiveness of the product by binding to metal ions that can cause degradation or discoloration. Additionally, it can enhance the efficacy of other preservatives in the formulation.

3. Usage Pentasodium Pentetate:

Pentasodium Pentetate is typically used in small concentrations in cosmetics, usually ranging from 0.1% to 0.5%. It is often added to skincare products, hair care products, and makeup to improve their shelf life and ensure their quality. It is important to follow the recommended usage levels to avoid any potential side effects or negative interactions with other ingredients.

Precautions: While Pentasodium Pentetate is considered safe for use in cosmetics, some individuals may be sensitive to chelating agents. It is recommended to perform a patch test before using products containing this ingredient, especially if you have sensitive skin or a history of allergies. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional.

4. References:

- "Pentasodium Pentetate," Cosmetics Info, www.cosmeticsinfo.org

- "Safety Assessment of Pentasodium Pentetate and Pentetic Acid," Cosmetic Ingredient Review, www.cir-safety.org

- "Pentasodium Pentetate in Cosmetics," Personal Care Products Council, www.personalcarecouncil.org