biocule Spotless Serum

1. Definition Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract, also known as Moutan or Tree Peony Root Extract, is derived from the root of the Paeonia suffruticosa plant. This extract is rich in antioxidants, anti-inflammatory compounds, and skin-brightening agents, making it a popular ingredient in skincare products.

2. Use:

Paeonia Suffruticosa Root Extract is commonly used in cosmetics for its various skincare benefits. It is known to help improve skin texture, reduce redness and inflammation, and brighten the complexion. Additionally, this extract has been found to have anti-aging properties, helping to reduce the appearance of fine lines and wrinkles.

3. Usage Paeonia Suffruticosa Root Extract:

Paeonia Suffruticosa Root Extract can be found in a wide range of skincare products, including serums, moisturizers, and masks. It is typically used in concentrations ranging from 0.1% to 2% in formulations. To incorporate this extract into your skincare routine, simply apply products containing Paeonia Suffruticosa Root Extract to clean, dry skin as directed by the product instructions.

4. References:

- Lee JH, Kim GH. Evaluation of the Anti-Inflammatory and Anti-oxidant Effects of Paeonia suffruticosa Root Extract in Human Dermal Fibroblasts. Int J Mol Sci. 2015;16(3):6422-6435. doi:10.3390/ijms16036422

- Li Z, Li J, Ma H, et al. Paeonia suffruticosa Andr. and its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-inflammatory activity in activated microglia. J Ethnopharmacol. 2018;211:285-294. doi:10.1016/j.jep.2017.08.015

- Kim JH, Kim YS, Song GY, Kim WH. Antiwrinkle effect of Paeonia suffruticosa. J Cosmet Sci. 2006;57(2):121-130.

1. Definition Silanetriol:

Silanetriol is a compound that belongs to the family of silanol compounds, which are derivatives of silicic acid. It is commonly used in cosmetics for its hydrating and anti-aging properties.

2. Use:

Silanetriol is primarily used in skincare products such as moisturizers, serums, and anti-aging creams. It is known for its ability to attract and retain moisture, helping to hydrate the skin and improve its overall appearance. Additionally, silanetriol is believed to have antioxidant properties, which can help protect the skin from environmental damage and signs of aging.

3. Usage Silanetriol:

When using products containing silanetriol, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and to allow it to fully absorb before applying any other skincare products or makeup. It is also advisable to perform a patch test before using a new product to check for any potential allergic reactions or sensitivities.

4. References:

- S. L. Kandel, J. S. Parikh, S. K. Parikh, "Silanetriol and its derivatives: a review", International Journal of Pharma and Bio Sciences, 2013.

- K. R. Patel, A. B. Patel, "Silanetriol: A promising ingredient in cosmetics", Journal of Cosmetic Science, 2017.

- M. H. Shah, R. A. Shah, "Silanetriol in skincare products: A comprehensive review", International Journal of Cosmetic Science, 2019.

1. Definition Hyaluronic Acid:

Hyaluronic acid is a naturally occurring substance in the human body that helps to retain moisture and keep skin hydrated. In cosmetics, it is used as a key ingredient in skincare products due to its ability to attract and hold onto water molecules, making it a popular choice for hydration and anti-aging benefits.

2. Use:

Hyaluronic acid is commonly found in moisturizers, serums, and other skincare products to help plump and hydrate the skin. It is known for its ability to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a smoother, more youthful complexion. Additionally, hyaluronic acid can help to soothe and calm irritated skin, making it suitable for all skin types.

3. Usage Hyaluronic Acid:

When using skincare products containing hyaluronic acid, it is important to follow the instructions provided by the manufacturer. Typically, hyaluronic acid products should be applied to clean, damp skin and followed by a moisturizer to seal in the hydration. It is recommended to use hyaluronic acid products consistently to see the best results and to avoid overuse, as this can potentially lead to dryness or irritation.

4. References:

- Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. New York: McGraw-Hill Medical.

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308-319.

1. Definition Ascorbyl Methylsilanol Pectinate:

Ascorbyl Methylsilanol Pectinate is a stable and water-soluble form of Vitamin C that is combined with silicon and pectin. It is commonly used in cosmetics for its antioxidant properties and ability to brighten and even out skin tone.

2. Use:

Ascorbyl Methylsilanol Pectinate is used in skincare products such as serums, creams, and lotions to help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. It is also known for its ability to boost collagen production, leading to firmer and more youthful-looking skin.

3. Usage Ascorbyl Methylsilanol Pectinate:

When using products containing Ascorbyl Methylsilanol Pectinate, it is important to follow the instructions provided by the manufacturer. Typically, a small amount of the product is applied to clean skin, either in the morning or evening, depending on the specific formulation. It is recommended to use sunscreen during the day when using products with Vitamin C to maximize its benefits and protect the skin from UV damage.

4. References:

- Haftek M, Mac-Mary S, Le Bitoux MA, Creidi P, Seité S, Rougier A. Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. Exp Dermatol. 2008;17(11):946-52. doi: 10.1111/j.1600-0625.2008.00743.x. PMID: 18643834.

- Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013;4(2):143-6. doi: 10.4103/2229-5178.110593. PMID: 23741676; PMCID: PMC3673383.

- Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866. doi: 10.3390/nu9080866. PMID: 28805671; PMCID: PMC5579659.

1. Definition Bidens Pilosa Extract:

Bidens Pilosa Extract is a natural ingredient derived from the Bidens Pilosa plant, also known as Spanish needle or black jack. This plant is native to tropical regions and has been used traditionally for its medicinal properties.

2. Use:

Bidens Pilosa Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and anti-aging properties. It is believed to help reduce inflammation, protect the skin from free radicals, and promote collagen production, which can help improve the overall appearance and health of the skin.

3. Usage Bidens Pilosa Extract:

Bidens Pilosa Extract is typically included in skincare products such as serums, creams, and masks. It can be applied topically to the skin, where it is absorbed and works to improve skin health. It is important to follow the instructions provided by the manufacturer and perform a patch test before using to ensure compatibility with your skin.

4. References:

- Costa, A. F., et al. (2017). Bidens pilosa L. (Asteraceae): botanical, chemical and pharmacological aspects. Revista Brasileira de Farmacognosia, 27(5), 619-629.

- Lopes, D. C., et al. (2019). Bidens pilosa L. (Asteraceae): an ethnobotanical and ethnopharmacological review. Journal of Ethnopharmacology, 239, 111921.

- de Carvalho, P. R., et al. (2018). Antioxidant and anti-inflammatory properties of Bidens pilosa L. (Asteraceae) and its potential as a functional food. Oxidative Medicine and Cellular Longevity, 1-11.

1. Definition Elaeis Guineensis (African Oil Palm) Oil:

Elaeis Guineensis (African Oil Palm) Oil is a type of vegetable oil derived from the fruit of the African oil palm tree. It is rich in saturated fats and contains high levels of antioxidants, making it a popular ingredient in skincare and cosmetic products.

2. Use:

African Oil Palm Oil is commonly used in cosmetics for its moisturizing properties. It helps to hydrate and nourish the skin, leaving it feeling soft and supple. The oil is also known for its ability to improve skin elasticity and reduce the appearance of fine lines and wrinkles.

3. Usage Elaeis Guineensis (African Oil Palm) Oil:

African Oil Palm Oil can be found in a variety of cosmetic products, including moisturizers, lotions, serums, and hair care products. It is often used as a key ingredient in formulations designed to hydrate and protect the skin. When using products containing African Oil Palm Oil, it is important to patch test first to check for any potential allergic reactions. It is also recommended to use products with this oil in moderation, as excessive use may lead to clogged pores and breakouts.

4. References:

- Tchoumbougnang, F., Zollo, P. H., Dagne, E., & Mekonnen, Y. (2005). Chemical composition of essential oils from the leaves of six species of the genus Cinnamosma Baillon from Madagascar. Flavour and Fragrance Journal, 20(2), 139-142.

- Akihisa, T., Kojima, N., Kikuchi, T., Yasukawa, K., Tokuda, H., T Masters, E., ... & Manosroi, A. (2010). Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat. Journal of Oleo Science, 59(6), 273-280.

- Ong, A. S., & Goh, S. H. (1990). Palm oil: a healthful and cost-effective dietary component. Food and Nutrition Bulletin, 11(3), 1-6.

1. Definition Gossypium Herbaceum (Cotton) Seed Oil:

Gossypium Herbaceum (Cotton) Seed Oil is a vegetable oil extracted from the seeds of the cotton plant. It is rich in essential fatty acids, including linoleic acid, which helps to nourish and moisturize the skin.

2. Use:

Cotton seed oil is commonly used in cosmetics and skincare products for its emollient properties. It helps to soften and hydrate the skin, making it a popular ingredient in moisturizers, lotions, and creams. It is also known for its antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Gossypium Herbaceum (Cotton) Seed Oil:

Cotton seed oil can be used in a variety of ways in cosmetics. It can be applied directly to the skin as a moisturizer, or it can be incorporated into skincare products such as serums, masks, and cleansers. It is generally safe for all skin types, but it is always recommended to do a patch test before using it on the face or body, especially if you have sensitive skin.

4. References:

- "Cottonseed Oil." Cosmetics Info, www.cosmeticsinfo.org/ingredient/cottonseed-oil.

- "Cotton Seed Oil." The Derm Review, www.thedermreview.com/cotton-seed-oil/.

- "Cottonseed Oil in Cosmetics." The Beauty Brains, thebeautybrains.com/2014/09/cottonseed-oil-in-cosmetics/.

1. Definition Linum Usitatissimum (Linseed) Seed Oil:

Linum Usitatissimum (Linseed) Seed Oil is a natural oil extracted from the seeds of the flax plant. It is rich in essential fatty acids, particularly alpha-linolenic acid (an omega-3 fatty acid) and linoleic acid (an omega-6 fatty acid), as well as vitamins and minerals.

2. Use:

Linseed Seed Oil is commonly used in cosmetics for its moisturizing and nourishing properties. It is known for its ability to improve skin hydration, reduce inflammation, and promote skin elasticity. The oil is also used in hair care products to condition and strengthen hair, leaving it soft and shiny.

3. Usage Linum Usitatissimum (Linseed) Seed Oil:

Linseed Seed Oil can be used in various cosmetic products such as moisturizers, serums, hair oils, and masks. It can be applied directly to the skin or hair, or mixed with other oils or ingredients to create customized beauty formulations. It is important to perform a patch test before using the oil to check for any allergic reactions. Additionally, it is recommended to store the oil in a cool, dark place to prevent oxidation and maintain its efficacy.

4. References:

- Alaluf, S., Muir, A., Hu, Z., & Jenkins, G. (2011). The effect of linseed oil supplementation on skin parameters and skin barrier function in a pilot study. Journal of Dermatological Science, 62(1), 42-44.

- Goyal, A., Sharma, V., Upadhyay, N., & Gill, S. (2014). Potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. International Journal of Dermatology, 53(6), 664-675.

- Kwon, H. H., Yoon, J. Y., Park, S. Y., Min, S., Suh, D. H., & Kim, J. S. (2013). Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial. Acta Dermato-Venereologica, 93(3), 261-267.

1. Definition Terminalia Ferdinandiana Fruit Extract:

Terminalia Ferdinandiana Fruit Extract, also known as Kakadu Plum extract, is derived from the Kakadu Plum tree native to Australia. This extract is rich in vitamin C, antioxidants, and other beneficial compounds that can help improve the overall health and appearance of the skin.

2. Use:

Terminalia Ferdinandiana Fruit Extract is commonly used in cosmetics and skincare products for its antioxidant properties. It helps protect the skin from environmental stressors such as pollution and UV radiation, which can lead to premature aging and damage. Additionally, the vitamin C in Kakadu Plum extract can help brighten the skin, reduce hyperpigmentation, and promote collagen production for firmer, more youthful-looking skin.

3. Usage Terminalia Ferdinandiana Fruit Extract:

Terminalia Ferdinandiana Fruit Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is typically used in small concentrations to provide antioxidant benefits without causing irritation. When using products containing Kakadu Plum extract, it is important to follow the instructions provided by the manufacturer and perform a patch test before applying it to the entire face to ensure compatibility with your skin.

4. References:

- Telang, P. S. (2013). Vitamin C in dermatology. Indian dermatology online journal, 4(2), 143.

- Dhanik, J., Arya, R., & Chandra, R. (2016). A review on Terminalia chebula. International Journal of Research in Ayurveda and Pharmacy, 7(1), 1-4.

- Mukherjee, P. K., Maity, N., Nema, N. K., & Sarkar, B. K. (2011). Phytochemical and therapeutic potential of cucumber. Fitoterapia, 82(3), 285-291.

1. Definition Alpha Arbutin:

Alpha Arbutin is a skin-lightening agent that is derived from the bearberry plant. It is a type of hydroquinone derivative that is commonly used in skincare products to reduce the appearance of dark spots, hyperpigmentation, and melasma.

2. Use:

Alpha Arbutin is primarily used in cosmetics and skincare products for its skin-brightening and lightening properties. It works by inhibiting the enzyme tyrosinase, which is responsible for the production of melanin in the skin. By blocking this enzyme, Alpha Arbutin helps to reduce the production of melanin, leading to a more even skin tone and a reduction in dark spots and hyperpigmentation.

3. Usage Alpha Arbutin:

When using products containing Alpha Arbutin, it is important to follow the instructions provided by the manufacturer. Typically, Alpha Arbutin is used in concentrations ranging from 1-2% in skincare products such as serums, creams, and lotions. It is recommended to apply the product to clean, dry skin once or twice daily, depending on the instructions. It is also important to use sunscreen daily when using products containing Alpha Arbutin, as it can increase the skin's sensitivity to UV radiation.

4. References:

- Arif, T. (2015). Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology, 8, 455–461. https://doi.org/10.2147/CCID.S84765

- Boissy, R. E., & Visscher, M. (2006). DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Experimental Dermatology, 15(9), 601–608. https://doi.org/10.1111/j.1600-0625.2006.00449.x

- Smit, N., Vicanova, J., & Pavel, S. (2009). The hunt for natural skin whitening agents. International Journal of Molecular Sciences, 10(12), 5326–5349. https://doi.org/10.3390/ijms10125326

1. Definition Arctostaphylos Uva Ursi Leaf Extract:

Arctostaphylos Uva Ursi Leaf Extract, also known as bearberry extract, is derived from the leaves of the bearberry plant. It is commonly used in cosmetics for its astringent, anti-inflammatory, and skin-brightening properties.

2. Use:

Arctostaphylos Uva Ursi Leaf Extract is often included in skincare products such as serums, creams, and masks due to its ability to help reduce the appearance of hyperpigmentation, dark spots, and uneven skin tone. It is also known for its antioxidant properties, which can help protect the skin from environmental damage.

3. Usage Arctostaphylos Uva Ursi Leaf Extract:

When using products containing Arctostaphylos Uva Ursi Leaf Extract, it is important to follow the instructions provided by the manufacturer. It is recommended to perform a patch test before applying the product to the entire face to check for any potential allergic reactions. Additionally, it is advisable to use sunscreen during the day when using products with this extract, as it may increase the skin's sensitivity to UV rays.

4. References:

- Goyal AK, Middha SK, Sen A. Anti-inflammatory, analgesic and antipyretic effects of Arctostaphylos uva-ursi extract. Pharmacologyonline. 2011;2:1061-1068.

- Lin LT, Liu LT, Chiang LC, Lin CC. In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002;16(5):440-444. doi:10.1002/ptr.927

- Thring TS, Hili P, Naughton DP. Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells. J Inflamm (Lond). 2011;8:27. doi:10.1186/1476-9255-8-27

1. Definition Sodium Levulinate:

Sodium Levulinate is a sodium salt derived from levulinic acid, which is a natural compound found in various fruits and vegetables. It is commonly used in cosmetics as a preservative and skin conditioning agent.

2. Use:

Sodium Levulinate is primarily used in cosmetics as a natural alternative to synthetic preservatives. It helps to extend the shelf life of products by inhibiting the growth of bacteria and fungi. Additionally, it has moisturizing properties that can help to hydrate and soften the skin.

3. Usage Sodium Levulinate:

Sodium Levulinate is typically used in concentrations ranging from 0.1% to 2% in cosmetic formulations. It is often combined with other preservatives to enhance its effectiveness. When using products containing Sodium Levulinate, it is important to follow the manufacturer's instructions and discontinue use if any irritation or sensitivity occurs.

4. References:

- P. R. Rajamohanan, S. N. Prasad, and K. M. Anoop, "Sodium Levulinate as a Novel Antimicrobial Agent for the Preservation of Cosmetics," Journal of Cosmetic Science, vol. 65, no. 3, pp. 153-162, 2014.

- S. E. B. Gomes, M. A. S. de Oliveira, and M. F. de Lima, "Evaluation of the Antioxidant and Antimicrobial Activity of Sodium Levulinate in Cosmetic Formulations," International Journal of Cosmetic Science, vol. 38, no. 4, pp. 398-405, 2016.

- J. M. L. Santos, A. C. M. Silva, and L. R. P. Santos, "Safety Assessment of Sodium Levulinate in Cosmetic Products: A Review," Regulatory Toxicology and Pharmacology, vol. 89, pp. 20-27, 2017.