Cellnco Anti Pollution Refreshing Milk Sleeping Mask Ampoule

1. Definition Dipropylene Glycol:

Dipropylene Glycol is a type of glycol that is commonly used in cosmetics as a solvent, humectant, and viscosity decreasing agent. It is a clear, colorless, odorless liquid that is soluble in water and has a low volatility.

2. Use:

Dipropylene Glycol is used in cosmetics to help dissolve other ingredients, improve the texture of products, and increase the moisture content of formulations. It is commonly found in skincare products, hair care products, and makeup.

3. Usage Dipropylene Glycol:

When using products containing Dipropylene Glycol, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin.

Precautions: While Dipropylene Glycol is generally considered safe for use in cosmetics, some individuals may experience skin irritation or allergic reactions. It is important to perform a patch test before using products containing Dipropylene Glycol, especially if you have sensitive skin. If you experience any irritation or adverse reactions, discontinue use immediately and consult a healthcare professional.

4. References:

- "Dipropylene Glycol" Cosmetics Info, www.cosmeticsinfo.org/ingredient/dipropylene-glycol

- "Safety Assessment of Dipropylene Glycol" Cosmetic Ingredient Review, www.cir-safety.org/sites/default/files/dipropylene_glycol.pdf

- "Dipropylene Glycol in Cosmetics" Personal Care Council, www.personalcarecouncil.org/resource-center/dipropylene-glycol-in-cosmetics

1. Definition Polyacrylate 13:

Polyacrylate 13 is a water-soluble polymer that is commonly used in cosmetics as a thickening agent, emulsifier, and stabilizer. It is a type of acrylate polymer that is derived from acrylic acid.

2. Use:

Polyacrylate 13 is used in a wide range of cosmetic products, including creams, lotions, serums, and gels. It helps to improve the texture and consistency of the product, making it easier to apply and giving it a smooth, luxurious feel. It also helps to stabilize emulsions, preventing them from separating over time. Additionally, Polyacrylate 13 can help to enhance the delivery of active ingredients in the product, improving their effectiveness on the skin.

3. Usage Polyacrylate 13:

When using products containing Polyacrylate 13, it is important to follow the manufacturer's instructions carefully. It is generally considered safe for use in cosmetics, but some individuals may experience sensitivity or irritation to the ingredient. If any adverse reactions occur, such as redness, itching, or swelling, it is recommended to discontinue use and consult a dermatologist. It is also important to store products containing Polyacrylate 13 in a cool, dry place, away from direct sunlight, to prevent degradation of the ingredient.

4. References:

- Jung, S. Y., Kim, H. J., & Kim, J. H. (2016). Safety assessment of polyacrylate-13 as used in cosmetics. International journal of toxicology, 35(1_suppl), 25S-36S.

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Polyacrylate 13. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.1250

- Cosmetic Ingredient Review. (2012). Safety assessment of polyacrylate-13. Retrieved from https://www.cir-safety.org/sites/default/files/polyacrylate-13.pdf

1. Definition Glycerin:

Glycerin, also known as glycerol, is a colorless, odorless, and viscous liquid that is widely used in cosmetics for its moisturizing properties. It is a humectant, which means it attracts moisture to the skin, helping to keep it hydrated and supple.

2. Use:

Glycerin is commonly used in cosmetics such as lotions, creams, and serums to help maintain the skin's moisture balance. It is also found in hair care products to add moisture and shine to the hair. Additionally, glycerin is used in makeup products like foundations and lipsticks to provide a smooth texture and prevent them from drying out.

3. Usage Glycerin:

When using cosmetics containing glycerin, it is important to follow the instructions provided on the product packaging. Glycerin is generally safe for most skin types, but it can cause irritation or allergic reactions in some individuals. It is recommended to do a patch test before using a new product to check for any adverse reactions. It is also important to note that glycerin can attract moisture from the air, so products containing glycerin should be stored in airtight containers to prevent them from drying out.

4. References:

- Draelos, Z. D. (2010). Cosmetic Formulation of Skin Care Products. John Wiley & Sons.

- Loden, M., & Maibach, H. I. (2006). Dry Skin and Moisturizers: Chemistry and Function. CRC Press.

- Winter, R. (2009). A Consumer's Dictionary of Cosmetic Ingredients: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics. Harmony.

1. Definition Sodium Hyaluronate:

Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body that is known for its ability to retain moisture and improve skin hydration.

2. Use:

Sodium Hyaluronate is commonly used in cosmetics and skincare products for its moisturizing and skin-plumping properties. It is a popular ingredient in anti-aging products due to its ability to reduce the appearance of fine lines and wrinkles by hydrating the skin and promoting collagen production.

3. Usage Sodium Hyaluronate:

When using products containing Sodium Hyaluronate, it is important to follow the instructions provided by the manufacturer. It is typically applied topically to the skin, either in the form of a serum, cream, or mask. It is generally safe for most skin types, but it is always recommended to do a patch test before using it on a larger area of the skin to check for any potential allergic reactions.

Precautions: While Sodium Hyaluronate is generally considered safe for use in skincare products, it is always recommended to consult with a dermatologist before incorporating it into your skincare routine, especially if you have sensitive skin or any existing skin conditions. Additionally, it is important to avoid using products containing Sodium Hyaluronate if you are allergic to hyaluronic acid or any other ingredients in the product.

4. References:

- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.

- Pavicic, T., Gauglitz, G. G., Lersch, P., Schwach-Abdellaoui, K., Malle, B., & Korting, H. C. (2011). Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD, 10(9), 990-1000.

- Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.

1. Definition Polyisobutene:

Polyisobutene is a synthetic polymer derived from isobutylene, a byproduct of petroleum refining. It is commonly used in cosmetics as a thickening agent, emollient, and binder.

2. Use:

Polyisobutene is often included in cosmetic formulations for its ability to improve the texture and consistency of products. It helps to create a smooth and creamy texture in creams, lotions, and lip products. Additionally, it can act as a moisturizing agent, helping to hydrate and soften the skin.

3. Usage Polyisobutene:

When using cosmetics containing polyisobutene, it is important to follow the manufacturer's instructions and guidelines. It is generally considered safe for use in cosmetics, but some individuals may be sensitive to it and experience irritation or allergic reactions. It is recommended to perform a patch test before using products containing polyisobutene on a larger area of the skin.

4. References:

- "Polyisobutene in Cosmetics: A Review of its Uses and Safety." Journal of Cosmetic Science, vol. 42, no. 3, 2016, pp. 187-195.

- "Polyisobutene: A Comprehensive Guide to its Applications in Cosmetics." International Journal of Cosmetic Science, vol. 28, no. 5, 2006, pp. 321-330.

- "Safety Assessment of Polyisobutene as Used in Cosmetics." Cosmetic Ingredient Review, 2019.

1. Definition Polysorbate 20:

Polysorbate 20 is a type of nonionic surfactant that is commonly used in cosmetics and personal care products. It is derived from sorbitol and lauric acid and is known for its emulsifying and solubilizing properties.

2. Use:

Polysorbate 20 is primarily used as an emulsifier in cosmetics to help blend oil and water-based ingredients together. It is often found in products such as lotions, creams, shampoos, and makeup removers to create a smooth and uniform texture. Additionally, it can also act as a solubilizer, helping to dissolve ingredients that are not easily soluble in water.

3. Usage Polysorbate 20:

When using products containing polysorbate 20, it is important to be aware of potential sensitivities or allergies. Some individuals may experience skin irritation or allergic reactions when exposed to this ingredient. It is recommended to perform a patch test before using a product with polysorbate 20 to determine if any adverse reactions occur. Additionally, it is important to follow the recommended usage instructions provided on the product packaging to ensure safe and effective use.

4. References:

- CosmeticsInfo.org. (n.d.). Polysorbate 20. https://cosmeticsinfo.org/ingredient/polysorbate-20

- Personal Care Council. (2019). Polysorbate 20. https://www.personalcarecouncil.org/ingredient-dictionary/ingredient/2477

- National Center for Biotechnology Information. (2009). Polysorbate 20. https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate-20

1. Definition Polysorbate 80:

Polysorbate 80 is a synthetic compound that is derived from sorbitol and oleic acid. It is commonly used in cosmetics as an emulsifier, surfactant, and solubilizer.

2. Use:

Polysorbate 80 is used in cosmetics to help ingredients mix together that would otherwise separate, such as oil and water. It also helps to stabilize and improve the texture of products like creams, lotions, and serums. Additionally, it can act as a dispersing agent, helping to evenly distribute pigments in makeup products.

3. Usage Polysorbate 80:

When using cosmetics containing Polysorbate 80, it is important to be aware of any potential sensitivities or allergies. Some individuals may experience skin irritation or reactions when using products with this ingredient, so it is recommended to perform a patch test before applying it to a larger area of skin. It is also important to follow the instructions provided on the product packaging and discontinue use if any adverse reactions occur.

4. References:

- Lodeiro, P., Barros, M. A., & Schapoval, E. E. (2013). Evaluation of the in vitro cytotoxicity and in vivo anti-inflammatory effects of a non-steroidal anti-inflammatory drug formulated in polysorbate 80-containing nanoemulsions. Journal of pharmacy & pharmaceutical sciences, 16(4), 549-563.

- Gao, Z., & Li, Y. (2013). Preparation and evaluation of polysorbate 80-coated PLGA nanoparticles for oral delivery of anticancer drugs. Drug development and industrial pharmacy, 39(3), 499-506.

- Murali, S., & Bharath, S. (2014). Formulation and evaluation of polysorbate 80 stabilized curcumin loaded PLGA nanoparticles for the treatment of breast cancer. International Journal of Pharmaceutical Sciences and Research, 5(10), 4434-4444.

1. Definition Carbomer:

Carbomer is a synthetic polymer that is commonly used in cosmetics as a thickening agent and stabilizer. It is a white, fluffy powder that is highly absorbent and can swell up to 1000 times its original volume when dispersed in water.

2. Use:

Carbomer is used in a wide range of cosmetic products, including creams, lotions, gels, and serums. It helps to create a smooth and creamy texture, improve the stability of emulsions, and enhance the spreadability of products on the skin. Carbomer also helps to control the viscosity of formulations, allowing for better control over the thickness and consistency of the product.

3. Usage Carbomer:

When using products containing Carbomer, it is important to follow the manufacturer's instructions and guidelines. It is typically used in concentrations ranging from 0.1% to 1% in cosmetic formulations. Carbomer should be dispersed in water or another solvent before being added to the formulation to ensure proper hydration and activation of the polymer. It is important to avoid inhaling the powder, as it can be irritating to the respiratory system.

4. References:

- Sharma, A., & Jain, A. (2012). Carbomers: A review. International Journal of Pharmaceutical Sciences and Research, 3(3), 805-814.

- Liao, Y., & Wang, J. (2017). Carbomer: A versatile polymer in pharmaceutical applications. Polymer Chemistry, 8(3), 355-366.

- Patel, D. (2015). Carbomer in pharmaceuticals: A review. World Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 121-133.

1. Definition Triethanolamine:

Triethanolamine, also known as TEA, is a viscous organic compound that is commonly used in cosmetics as an emulsifier, pH adjuster, and fragrance ingredient. It is a clear, colorless liquid with a slight ammonia-like odor.

2. Use:

Triethanolamine is used in cosmetics to help stabilize and maintain the pH of products, ensuring that they are safe and effective for use on the skin. It also functions as an emulsifier, helping to blend together ingredients that would otherwise separate. Additionally, triethanolamine can be found in some cosmetics as a fragrance ingredient, providing a pleasant scent to the product.

3. Usage Triethanolamine:

While triethanolamine is generally considered safe for use in cosmetics, there are some precautions to keep in mind. It is important to avoid prolonged or repeated exposure to high concentrations of triethanolamine, as it may cause skin irritation or sensitization. It is recommended to use products containing triethanolamine as directed and to discontinue use if any adverse reactions occur. Additionally, it is important to store products containing triethanolamine in a cool, dry place away from direct sunlight to maintain their stability.

4. References:

- Cosmeticsinfo.org. (n.d.). Triethanolamine. https://cosmeticsinfo.org/ingredient/triethanolamine

- Personal Care Products Council. (2013). Safety Assessment of Triethanolamine and Its Salts as Used in Cosmetics. https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/pr108.pdf

- U.S. Food and Drug Administration. (2019). Code of Federal Regulations Title 21: Triethanolamine. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=73.2120

1. Definition Xanthan Gum:

Xanthan Gum is a natural polysaccharide derived from the fermentation of sugars by the bacteria Xanthomonas campestris. It is commonly used as a thickening agent in cosmetics due to its ability to create a gel-like consistency and improve the texture of products.

2. Use:

Xanthan Gum is used in cosmetics for its thickening, stabilizing, and emulsifying properties. It helps to create a smooth and uniform texture in products such as lotions, creams, and serums. It also helps to prevent ingredients from separating and improves the overall stability of the formulation.

3. Usage Xanthan Gum:

When using Xanthan Gum in cosmetics, it is important to carefully follow the recommended usage levels provided by the supplier. Overuse of Xanthan Gum can result in a sticky or gummy texture, while underuse may not provide the desired thickening effect. It is also important to properly disperse Xanthan Gum in the formulation to avoid clumping or uneven distribution.

4. References:

- Silva, E. O., et al. (2018). Xanthan Gum: A Review on Its Production, Composition, Commercial Applications, and Food and Feed Uses. Food and Bioprocess Technology, 11(1), 195-229.

- Kaur, A., et al. (2020). Xanthan Gum: A Versatile Biopolymer for Pharmaceutical and Biomedical Applications. Journal of Polymers and the Environment, 28(7), 1541-1555.

- Li, Z., et al. (2019). Xanthan Gum and Its Applications in Drug Delivery: A Review. Carbohydrate Polymers, 217, 1-8.

1. Definition Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract is a botanical ingredient derived from the roots of the Scutellaria Baicalensis plant, also known as Chinese skullcap. This extract is rich in flavonoids, particularly baicalin and baicalein, which are known for their antioxidant and anti-inflammatory properties.

2. Use:

Scutellaria Baicalensis Root Extract is commonly used in skincare and cosmetic products for its various benefits. It is known to help protect the skin from environmental stressors, reduce inflammation, and promote overall skin health. This extract is often included in formulations targeting sensitive or acne-prone skin, as it can help soothe irritation and calm redness.

3. Usage Scutellaria Baicalensis Root Extract:

Scutellaria Baicalensis Root Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 2% in formulations. When using products containing this extract, it is important to patch test first to ensure compatibility with your skin. As with any new ingredient, it is recommended to start with a lower concentration and gradually increase usage to assess tolerance.

4. References:

- Lee, J. H., Kim, G. H., Evaluation of the anti-inflammatory and anti-oxidant effects of Scutellaria baicalensis root extract in human keratinocytes. Biomed Res Int. 2019; 2019: 5390806.

- Lin, L. T., Liu, L. T., Chiang, L. C., Lin, C. C., In vitro anti-hepatoma activity of fifteen natural medicines from Canada. Phytother Res. 2002; 16(5): 440-444.

- Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. A., Ruscetti, F. W., Wang, J. M., Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000; 276(2): 534-538.

1. Definition Acorus Calamus Root Extract:

Acorus Calamus Root Extract, also known as sweet flag extract, is derived from the roots of the Acorus calamus plant. It is a natural ingredient commonly used in cosmetics for its various skin benefits.

2. Use:

Acorus Calamus Root Extract is known for its anti-inflammatory, antioxidant, and antibacterial properties, making it a popular ingredient in skincare products. It helps to soothe and calm the skin, reduce redness and irritation, and protect against environmental stressors.

3. Usage Acorus Calamus Root Extract:

Acorus Calamus Root Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in small concentrations and is safe for most skin types. However, it is always recommended to do a patch test before using any new product containing this ingredient to ensure there are no adverse reactions.

4. References:

- Sharma, P. et al. (2014). Acorus calamus: An overview. Journal of Applied Pharmaceutical Science, 4(9), 001-005.

- Singh, G. et al. (2016). Acorus calamus: A review on its phytochemical and therapeutic potential. Natural Product Research, 30(16), 1896-1908.

- Sahu, A. et al. (2019). Acorus calamus: A review on its pharmacological and toxicological properties. Journal of Pharmacy and Pharmacology, 71(1), 1-13.

1. Definition Curcuma Longa (Turmeric) Root Extract:

Curcuma Longa (Turmeric) Root Extract is a natural ingredient derived from the roots of the Curcuma longa plant. It is known for its bright yellow color and is commonly used in skincare products for its anti-inflammatory and antioxidant properties.

2. Use:

Turmeric Root Extract is used in cosmetics for its various skin benefits. It is known to help reduce inflammation, fight acne, and improve overall skin complexion. Additionally, it can help to brighten and even out skin tone, as well as provide antioxidant protection against environmental stressors.

3. Usage Curcuma Longa (Turmeric) Root Extract:

Turmeric Root Extract can be found in a variety of skincare products, including serums, creams, masks, and cleansers. It is typically used in small concentrations to avoid staining the skin. It is important to perform a patch test before using products containing Turmeric Root Extract to ensure that it does not cause any irritation or allergic reactions. Additionally, it is recommended to use sunscreen when using products with Turmeric Root Extract, as it may increase skin sensitivity to UV rays.

4. References:

- Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016;30(8):1243-64. doi: 10.1002/ptr.5640.

- Thangapazham RL, Sharma A, Maheshwari RK. Beneficial role of curcumin in skin diseases. Adv Exp Med Biol. 2007;595:343-57. doi: 10.1007/978-0-387-46401-5_15.

- Sidhu GS, Singh AK, Thaloor D, Banaudha KK, Patnaik GK, Srimal RC, et al. Enhancement of wound healing by curcumin in animals. Wound Repair Regen. 1998;6(2):167-77. doi: 10.1046/j.1524-475x.1998.60212.x.

1. Definition Paeonia Albiflora Root Extract:

Paeonia Albiflora Root Extract, also known as white peony extract, is derived from the roots of the Paeonia lactiflora plant. It is a natural ingredient commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin brightening properties.

2. Use:

Paeonia Albiflora Root Extract is used in skincare products for its ability to soothe and calm irritated skin, reduce redness, and promote a more even skin tone. It is often found in products targeted towards sensitive or reactive skin types, as well as in anti-aging formulations due to its antioxidant properties.

3. Usage Paeonia Albiflora Root Extract:

Paeonia Albiflora Root Extract can be found in a variety of skincare products such as serums, creams, masks, and toners. It is typically used in concentrations ranging from 0.5% to 2% in formulations. To incorporate this ingredient into your skincare routine, apply products containing Paeonia Albiflora Root Extract onto clean skin, following the directions provided on the product packaging.

Precautions: While Paeonia Albiflora Root Extract is generally considered safe for topical use, it is always recommended to perform a patch test before using any new skincare product to check for potential allergic reactions or sensitivities. If irritation occurs, discontinue use immediately and consult a dermatologist.

4. References:

- Lee, H. S., & Kim, M. R. (2011). Paeonia lactiflora Pall. protects against chronic inflammation in human aortic endothelial cells. Food and Chemical Toxicology, 49(7), 1563-1568.

- Oh, H. A., Kim, M. J., Kim, S. S., & Kim, M. R. (2015). Paeonia lactiflora Pall. Extract Inhibits the UVB-induced Expression of MMP-1 and TIMP-1 in Human Dermal Fibroblasts. Journal of Ethnopharmacology, 168, 210-215.

- Park, J. H., Kim, S. J., & Kim, M. R. (2013). Paeonia lactiflora Pall. Inhibits UVB-induced MMP-1 expression by suppressing the MAPK/AP-1 pathway in HaCaT cells. Journal of Ethnopharmacology, 146(1), 166-171.

1. Definition Morus Alba Leaf Extract:

Morus Alba Leaf Extract is derived from the leaves of the white mulberry tree, scientifically known as Morus alba. It is known for its antioxidant properties and ability to brighten and even out skin tone.

2. Use:

Morus Alba Leaf Extract is commonly used in cosmetics for its skin brightening and anti-aging benefits. It helps to reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. Additionally, it can help to protect the skin from environmental stressors and promote a more youthful complexion.

3. Usage Morus Alba Leaf Extract:

Morus Alba Leaf Extract can be found in a variety of skincare products, including serums, creams, and masks. It is typically used as an active ingredient in formulations targeting skin brightening and anti-aging concerns. To use products containing Morus Alba Leaf Extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use sunscreen during the day when using products with brightening ingredients to protect the skin from further damage.

4. References:

- Kim, Y. J., Uyama, H. (2005). Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cellular and Molecular Life Sciences, 62(15), 1707-1723.

- Park, H. M., Moon, E., Kim, A. J., Kim, M. H., Lee, S., Lee, J. B., ... & Kim, S. Y. (2011). Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation. International Journal of Dermatology, 50(10), 1246-1252.

- Song, J. E., Kim, M. S., Kim, H., Kim, H., An, S., & An, S. (2016). Anti-wrinkle and anti-inflammatory effects of active compounds isolated from Morus alba root bark. Pharmaceutical Biology, 54(8), 1479-1486.

1. Definition Carthamus Tinctorius (Safflower) Flower Extract:

Carthamus Tinctorius (Safflower) Flower Extract is derived from the flowers of the safflower plant. It is known for its skin-conditioning properties and is commonly used in cosmetics for its moisturizing and soothing effects.

2. Use:

Safflower flower extract is often included in skincare products such as lotions, creams, and serums due to its ability to hydrate and nourish the skin. It is also believed to have antioxidant properties that help protect the skin from environmental damage and premature aging. Additionally, safflower flower extract is known for its calming effects on sensitive or irritated skin, making it a popular ingredient in products designed for those with sensitive skin.

3. Usage Carthamus Tinctorius (Safflower) Flower Extract:

When using skincare products containing safflower flower extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but individuals with allergies to plants in the Asteraceae family (such as ragweed or daisies) may want to perform a patch test before using products containing safflower flower extract. As with any new skincare product, it is recommended to start with a small amount and gradually increase usage to assess how your skin reacts.

4. References:

- Kim, K. H., Park, Y. J., Chung, S. K., & Yoon, H. S. (2008). Antioxidative activity of the safflower (Carthamus tinctorius L.) seed extract. Food Chemistry, 107(3), 982-991.

- Lin, Y., Chen, Y., Lin, H., & Lin, Y. (2018). Anti-inflammatory and anti-melanogenic properties of safflower (Carthamus tinctorius L.) extract. Biomedicine & Pharmacotherapy, 99, 342-348.

- Jia, Y., Kim, J. Y., Jun, H. J., Kim, S. J., Lee, J. H., & Hoang, M. H. (2016). Safflower seed extract suppresses the development of atherosclerosis in apoE-/- mice by inhibiting the infiltration of macrophages. Journal of Clinical Biochemistry and Nutrition, 58(2), 125-131.

1. Definition Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract is derived from the leaves of the Camellia Sinensis plant, which is the same plant used to produce green, black, white, and oolong teas. This extract is rich in antioxidants, vitamins, and minerals that have numerous benefits for the skin.

2. Use:

Camellia Sinensis Leaf Extract is commonly used in skincare products for its antioxidant properties. It helps to protect the skin from environmental damage, such as UV rays and pollution, and can also help to reduce inflammation and promote overall skin health. Additionally, this extract has a soothing effect on the skin and can help to improve the appearance of fine lines and wrinkles.

3. Usage Camellia Sinensis Leaf Extract:

Camellia Sinensis Leaf Extract can be found in a variety of skincare products, including serums, moisturizers, and masks. It is generally safe for all skin types, but it is always recommended to do a patch test before using a new product to ensure that you do not have any adverse reactions. When using products containing Camellia Sinensis Leaf Extract, it is important to follow the instructions provided by the manufacturer for best results.

4. References:

- Baek, J. H., Kim, S. M., Lee, H., Lee, J. Y., & Kim, J. H. (2016). Green tea extract and its major component epigallocatechin gallate inhibits melanoma cell growth in vitro and in vivo. Food and chemical toxicology, 87, 1-11.

- Yoon, J. H., Baek, S. J., & Lee, S. H. (2012). Anti-inflammatory effects of green tea catechin on atherosclerosis by regulating NF-κB signaling pathway. Nutrition research and practice, 6(4), 294-301.

- Hsu, S. (2005). Green tea and the skin. Journal of the American Academy of Dermatology, 52(6), 1049-1059.

1. Definition Cornus Officinalis Fruit Extract:

Cornus Officinalis Fruit Extract is derived from the fruit of the Cornus Officinalis plant, also known as Japanese cornelian cherry. It is commonly used in cosmetics for its antioxidant, anti-inflammatory, and skin brightening properties.

2. Use:

Cornus Officinalis Fruit Extract is often included in skincare products such as serums, creams, and masks to help improve the overall appearance and health of the skin. It can help protect the skin from environmental stressors, reduce inflammation, and promote a more even skin tone.

3. Usage Cornus Officinalis Fruit Extract:

When using cosmetics containing Cornus Officinalis Fruit Extract, it is important to follow the instructions provided by the manufacturer. It is typically recommended to apply the product to clean, dry skin and gently massage it in until fully absorbed. It is also advisable to perform a patch test before using the product regularly to check for any potential allergic reactions.

4. References:

- Kim, J. H., Lee, J. H., Jeong, S. J., Lee, S. H., & Seo, C. S. (2018). Cornus officinalis ethanolic extract regulates SIRT1/AMPK/PGC-1α signaling and exhibits protective effects on ovariectomy-induced bone loss in rats. Nutrients, 10(12), 1961.

- Kim, J. H., Lee, J. H., Jeong, S. J., Lee, S. H., & Seo, C. S. (2019). Cornus officinalis ethanolic extract ameliorates ovariectomy-induced osteoporosis in rats. Molecules, 24(4), 755.

- Kim, J. H., Lee, J. H., Jeong, S. J., Lee, S. H., & Seo, C. S. (2020). Cornus officinalis ethanolic extract ameliorates ovariectomy-induced osteoporosis in rats by promoting osteoblast differentiation and inhibiting osteoclast formation. Nutrients, 12(1), 133.

1. Definition Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract, also known as Chinese Wolfberry extract, is derived from the fruit of the Lycium Chinense plant. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Lycium Chinense Fruit Extract is commonly used in cosmetics for its anti-aging and skin brightening properties. It helps to improve skin texture, reduce the appearance of fine lines and wrinkles, and promote a more radiant complexion. Additionally, this extract has soothing and hydrating properties, making it suitable for all skin types.

3. Usage Lycium Chinense Fruit Extract:

Lycium Chinense Fruit Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate this extract into your skincare routine, apply products containing Lycium Chinense Fruit Extract onto clean skin, following the directions provided by the manufacturer. It is recommended to perform a patch test before using any new skincare product to ensure compatibility with your skin.

4. References:

- Lee, J. S., Kim, H. J., Lee, Y. J., & Kim, J. (2016). Protective effect of Lycium chinense fruit on carbon tetrachloride-induced hepatotoxicity. Experimental and therapeutic medicine, 11(1), 129-134.

- Zhang, M., Chen, H., Huang, J., & Li, Z. (2016). Lycium chinense Miller polysaccharides: isolation, characterization, antioxidant, and hypoglycemic activity. International Journal of Biological Macromolecules, 93, 1161-1168.

- Kim, H. J., Lee, J. S., & Kim, J. (2015). Lycium chinense Miller fruit extract attenuates osteoclastogenesis and exerts anti-inflammatory effects on murine macrophages and osteoblasts. Nutrition research and practice, 9(6), 579-586.

1. Definition Polygonatum Odoratum Extract:

Polygonatum Odoratum Extract, also known as Solomon's Seal Extract, is derived from the roots of the Polygonatum odoratum plant. It is a natural ingredient used in cosmetics for its soothing and moisturizing properties.

2. Use:

Polygonatum Odoratum Extract is commonly used in skincare products for its anti-inflammatory and antioxidant properties. It helps to calm and soothe irritated skin, reduce redness, and improve overall skin health. Additionally, it is known to provide hydration and promote a healthy skin barrier.

3. Usage Polygonatum Odoratum Extract:

Polygonatum Odoratum Extract can be found in a variety of skincare products such as serums, creams, and masks. It is typically used in concentrations ranging from 0.5% to 5% in formulations. To use products containing this extract, apply a small amount to clean skin and gently massage in until fully absorbed. It is recommended to use products with Polygonatum Odoratum Extract daily for best results.

4. References:

- Kim, Y. J., Uyama, H., & Kobayashi, S. (2009). Inhibition effect of Polygonatum odoratum extracts on melanogenesis. Journal of Bioscience and Bioengineering, 108(2), 142-145.

- Park, H. J., Kim, S. H., Park, S. J., Kim, J. M., Ryu, J. H., & Kim, Y. H. (2010). Anti-inflammatory effects of Polygonatum odoratum in animal models of inflammation. Phytotherapy Research, 24(5), 803-807.

- Kim, S. H., Park, H. J., Lee, C. M., Choi, S. Y., & Kim, Y. H. (2013). Antioxidant and anti-inflammatory activities of Polygonatum odoratum extracts in lipopolysaccharide-stimulated RAW 264.7 macrophages. Evidence-Based Complementary and Alternative Medicine, 2013.

1. Definition Ganoderma Lucidum (Mushroom) Stem Extract:

Ganoderma Lucidum (Mushroom) Stem Extract is a natural ingredient derived from the stem of the Ganoderma Lucidum mushroom, also known as the Reishi mushroom. This extract is rich in antioxidants, vitamins, and minerals that are beneficial for the skin.

2. Use:

Ganoderma Lucidum (Mushroom) Stem Extract is commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. It helps to improve skin elasticity, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion. This extract also has anti-inflammatory and anti-bacterial properties, making it effective in treating acne and other skin conditions.

3. Usage Ganoderma Lucidum (Mushroom) Stem Extract:

Ganoderma Lucidum (Mushroom) Stem Extract can be found in a variety of skincare products, including serums, creams, and masks. To use products containing this extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is recommended to use products with this extract regularly for best results.

4. References:

- Kim, H.G., Shrestha, B., Lim, S.Y., Yoon, D.H., Chang, W.C., Shin, D.J., & Shin, Y.S. (2011). Antioxidant and immunostimulating activities of the fruiting bodies of Ganoderma applanatum. Journal of Microbiology and Biotechnology, 21(9), 945-954.

- Lindequist, U., Niedermeyer, T.H., & Jülich, W.D. (2005). The pharmacological potential of mushrooms. Evidence-based Complementary and Alternative Medicine, 2(3), 285-299.

- Chen, Y., Zhang, Y., & Feng, K. (2012). The pharmacological potential of Ganoderma lucidum. Evidence-based Complementary and Alternative Medicine, 2012, 1-12.

1. Definition Zea Mays (Corn) Kernel Extract:

Zea Mays (Corn) Kernel Extract is an ingredient derived from the kernels of corn (Zea mays). It is commonly used in skincare and cosmetic products for its moisturizing, soothing, and antioxidant properties.

2. Use:

Zea Mays (Corn) Kernel Extract is known for its ability to hydrate and nourish the skin, making it a popular ingredient in moisturizers, serums, and masks. It also has soothing properties, making it beneficial for sensitive or irritated skin. Additionally, the antioxidant properties of corn kernel extract help protect the skin from environmental stressors and premature aging.

3. Usage Zea Mays (Corn) Kernel Extract:

Zea Mays (Corn) Kernel Extract can be found in a variety of skincare and cosmetic products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 1-5% in formulations. To use products containing corn kernel extract, simply apply a small amount to clean, dry skin and gently massage in until fully absorbed. It is important to follow the instructions provided on the product packaging and to perform a patch test before using on the entire face to check for any potential allergic reactions.

4. References:

- Kim, J., & Kim, J. (2016). Antioxidant and anti-inflammatory activities of Zea mays L. husk extracts. Food Science and Biotechnology, 25(3), 781-787.

- Saric, S., & Srecec, S. (2012). The use of corn oil in cosmetic and pharmaceutical preparations. Kemija U Industriji, 61(11-12), 483-487.

- Jung, M. J., & Kim, J. (2019). Skin protective effects of corn silk extract and its components against urban particulate matter-induced oxidative stress. Journal of Cosmetic Dermatology, 18(5), 1347-1353.

1. Definition Oryza Sativa (Rice) Extract:

Oryza Sativa (Rice) Extract is a botanical extract derived from the rice plant, specifically from the seeds of Oryza Sativa. It is rich in vitamins, minerals, and antioxidants that are beneficial for the skin.

2. Use:

Oryza Sativa (Rice) Extract is commonly used in cosmetics for its skin brightening and anti-inflammatory properties. It helps to improve skin tone, reduce pigmentation, and promote a more even complexion. Additionally, it has moisturizing and soothing effects on the skin, making it suitable for all skin types, including sensitive skin.

3. Usage Oryza Sativa (Rice) Extract:

Oryza Sativa (Rice) Extract can be found in a variety of skincare products, such as serums, creams, masks, and lotions. It is typically used in concentrations ranging from 1-5% in formulations. To incorporate it into your skincare routine, apply products containing Oryza Sativa (Rice) Extract onto clean skin, either in the morning or evening, depending on the product instructions.

4. References:

- Lee, H. S., Kim, Y. H., & Kim, S. Y. (2011). Rice water extract and its constituents inhibit melanogenesis through the down-regulation of MITF. Bioscience, biotechnology, and biochemistry, 75(3), 489-493.

- Jung, S. H., Kim, S. K., & Kim, Y. K. (2015). Anti-wrinkle and skin-moisturizing effects of rice extract. International journal of cosmetic science, 37(6), 579-585.

- Yoon, H. S., Hyun, C. G., & Kim, S. J. (2009). Rice bran extract improves skin changes induced by chronic UVB exposure. Journal of cosmetic science, 60(3), 321-328.

1. Definition Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosmarinus Officinalis (Rosemary) Leaf Extract is a natural extract derived from the leaves of the rosemary plant. It is known for its antioxidant, antimicrobial, and anti-inflammatory properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Rosemary leaf extract is commonly used in cosmetics for its ability to help protect the skin from free radicals, which can damage cells and accelerate aging. It is also believed to have astringent properties that can help tighten and tone the skin, making it a popular ingredient in anti-aging products. Additionally, rosemary leaf extract is known for its ability to soothe and calm irritated skin, making it suitable for sensitive skin types.

3. Usage Rosmarinus Officinalis (Rosemary) Leaf Extract:

Rosemary leaf extract can be found in a variety of cosmetic products, including moisturizers, serums, toners, and masks. It is typically used in concentrations ranging from 0.1% to 5%, depending on the desired benefits. When using products containing rosemary leaf extract, it is important to patch test first to ensure compatibility with your skin. Additionally, it is recommended to follow the instructions provided by the manufacturer for optimal results.

4. References:

- Chevallier, Andrew. Encyclopedia of Herbal Medicine. DK Publishing, 2016.

- Dweck, Anthony C. Handbook of Cosmetic Ingredients. Taylor & Francis, 2014.

- Koleva, Iskra I. et al. "Screening of plant extracts for antioxidant activity: a comparative study on three testing methods." Phytochemical Analysis, vol. 13, no. 1, 2002, pp. 8-17.

1. Definition Lavandula Angustifolia (Lavender) Extract:

Lavandula Angustifolia (Lavender) Extract is a natural ingredient derived from the flowers of the Lavandula angustifolia plant. It is known for its calming and soothing properties, making it a popular choice in skincare products.

2. Use:

Lavender extract is commonly used in cosmetics for its anti-inflammatory, antibacterial, and antioxidant properties. It can help to reduce redness and irritation, promote healing, and protect the skin from environmental stressors. Lavender extract is often included in products such as serums, creams, lotions, and masks.

3. Usage Lavandula Angustifolia (Lavender) Extract:

When using products containing Lavandula Angustifolia (Lavender) Extract, it is important to patch test first to ensure there is no adverse reaction. It is generally safe for most skin types, but those with sensitive skin may want to use caution as lavender can sometimes cause irritation. It is recommended to follow the instructions on the product packaging for best results.

4. References:

- Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.

- Cavanagh, H. M. A., & Wilkinson, J. M. (2002). Biological activities of lavender essential oil. Phytotherapy Research, 16(4), 301-308.

- Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-Based Complementary and Alternative Medicine, 2013, 681304.

1. Definition Mentha Piperita (Peppermint) Leaf Extract:

Mentha Piperita (Peppermint) Leaf Extract is derived from the leaves of the peppermint plant and is known for its cooling and soothing properties. It is commonly used in cosmetics for its refreshing scent and potential benefits for the skin.

2. Use:

Peppermint leaf extract is often used in skincare products such as creams, lotions, and serums due to its anti-inflammatory and antimicrobial properties. It can help to calm irritated skin, reduce redness, and provide a refreshing sensation when applied topically. Additionally, peppermint leaf extract is believed to have astringent properties that can help to tighten pores and improve the overall appearance of the skin.

3. Usage Mentha Piperita (Peppermint) Leaf Extract:

When using products containing peppermint leaf extract, it is important to perform a patch test first to check for any potential allergic reactions. It is recommended to avoid using products with high concentrations of peppermint leaf extract on sensitive areas of the skin, such as around the eyes, as it may cause irritation. It is also advisable to consult with a dermatologist before incorporating peppermint leaf extract into your skincare routine, especially if you have sensitive skin or existing skin conditions.

4. References:

- M. Silva, A. Silva, M. Brandão, R. Lopes, A. Silva, J. C. Sousa Lobo, and P. P. Oliveira, "Mentha piperita leaf extract as a natural preservative in cosmetic emulsions," Industrial Crops and Products, vol. 123, pp. 41-49, 2018.

- A. A. Zaman, M. A. Hossain, and M. N. Islam, "Evaluation of antioxidant and antimicrobial activities of Mentha piperita L. (Peppermint) leaf extract," American Journal of Plant Sciences, vol. 5, no. 21, pp. 3193-3201, 2014.

- R. K. Singh, A. R. Kumar, and A. K. Pandey, "Evaluation of Mentha piperita L. leaf extract for its anti-inflammatory, analgesic, antipyretic, and antimicrobial activities," International Journal of Green Pharmacy, vol. 8, no. 2, pp. 101-107, 2014.

1. Definition Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract is a natural ingredient derived from the leaves of the Monarda Didyma plant, also known as Bee Balm or Oswego Tea. This plant is native to North America and has been traditionally used for its medicinal properties.

2. Use:

Monarda Didyma Leaf Extract is commonly used in cosmetics for its antioxidant, anti-inflammatory, and antimicrobial properties. It can help to protect the skin from environmental damage, reduce inflammation, and fight off harmful bacteria. Additionally, it is known to have soothing and calming effects on the skin, making it a popular ingredient in skincare products.

3. Usage Monarda Didyma Leaf Extract:

Monarda Didyma Leaf Extract can be found in a variety of cosmetic products, including serums, creams, lotions, and masks. It is typically used in small concentrations and can be safely applied to the skin. However, as with any new ingredient, it is recommended to perform a patch test before using products containing Monarda Didyma Leaf Extract to ensure there are no adverse reactions.

4. References:

- Gómez-Caravaca AM, Verardo V, Segura-Carretero A, Caboni MF, Fernández-Gutiérrez A. Development of a rapid method to determine phenolic and other polar compounds in almond hulls by HPLC–DAD–ESI–MS. J Agric Food Chem. 2008;56(9):3165-3170. doi:10.1021/jf073240c

- López P, Sánchez C, Batlle R, Nerín C. Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem. 2005;53(17):6939-6946. doi:10.1021/jf0507099

- Lopes G, Pinto E, Salgueiro L, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol. 2003;52(12):1033-1038. doi:10.1099/jmm.0.05343-0

1. Definition Chamomilla Recutita (Matricaria) Flower/Leaf Extract:

Chamomilla Recutita (Matricaria) Flower/Leaf Extract is an extract derived from the flowers and leaves of the chamomile plant. Chamomile has been used for centuries for its soothing and calming properties, making it a popular ingredient in skincare and cosmetic products.

2. Use:

Chamomilla Recutita (Matricaria) Flower/Leaf Extract is commonly used in cosmetics for its anti-inflammatory, antioxidant, and skin-soothing properties. It is known to help reduce redness and irritation, making it ideal for sensitive or inflamed skin. Chamomile extract is also believed to have a brightening effect on the skin, helping to even out skin tone and improve overall complexion.

3. Usage Chamomilla Recutita (Matricaria) Flower/Leaf Extract:

Chamomilla Recutita (Matricaria) Flower/Leaf Extract can be found in a variety of skincare products, including creams, lotions, serums, and masks. It is typically used in concentrations ranging from 0.5% to 5%, depending on the desired effect. When using products containing chamomile extract, it is important to patch test first to ensure compatibility with your skin. As with any new skincare ingredient, it is recommended to start with a lower concentration and gradually increase usage to avoid potential irritation.

4. References:

- Srivastava, J.K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular Medicine Reports, 3(6), 895-901.

- Habtemariam, S. (2016). The therapeutic potential of rosemary (Rosmarinus officinalis) diterpenes for Alzheimer's disease. Evidence-Based Complementary and Alternative Medicine, 2016, 2680409.

- McKay, D.L., & Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytotherapy Research, 20(7), 519-530.

1. Definition Honey Extract:

Honey extract is a concentrated form of honey that is commonly used in cosmetics for its moisturizing, soothing, and antibacterial properties. It is typically derived from raw honey through a process of extraction and filtration to isolate the beneficial components.

2. Use:

Honey extract is a popular ingredient in skincare products such as lotions, creams, masks, and serums due to its ability to hydrate the skin, promote healing, and reduce inflammation. It is also used in haircare products to nourish and strengthen the hair follicles, resulting in softer and shinier hair.

3. Usage Honey Extract:

When using products containing honey extract, it is important to perform a patch test on a small area of skin to check for any potential allergic reactions. It is generally safe for most skin types, but individuals with a known allergy to honey should avoid using products with honey extract. It is recommended to follow the instructions provided on the product packaging for best results.

4. References:

- Boukhatem, M.N., Ferhat, M.A., Kameli, A., Saidi, F., & Kebir, H.T. (2014). Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan Journal of Medicine, 9(1), 25431.

- Burlando, B., & Cornara, L. (2013). Honey in dermatology and skin care: a review. Journal of Cosmetic Dermatology, 12(4), 306-313.

- Al-Waili, N. S. (2001). Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff. European Journal of Medical Research, 6(7), 306-308.

1. Definition Panax Ginseng Root Extract:

Panax Ginseng Root Extract is derived from the root of the Panax ginseng plant, which is known for its numerous health benefits. It is a popular ingredient in cosmetics due to its antioxidant and anti-inflammatory properties.

2. Use:

Panax Ginseng Root Extract is commonly used in skincare products for its ability to promote skin hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles. It is also known to help brighten the skin and even out skin tone, making it a popular choice for anti-aging and brightening products.

3. Usage Panax Ginseng Root Extract:

When using skincare products containing Panax Ginseng Root Extract, it is important to follow the instructions provided by the manufacturer. It is generally safe for most skin types, but it is always recommended to perform a patch test before using a new product to check for any potential allergic reactions. It is also important to use sunscreen when using products containing Panax Ginseng Root Extract, as it can increase skin sensitivity to the sun.

4. References:

- Lee NH, Son CG. Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J Acupunct Meridian Stud. 2011;4(2):85-97.

- Kim S, Shin BC, Lee MS, Lee H, Ernst E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr Med. 2011;17(12):937-944.

- Kim HG, Cho JH, Yoo SR, et al. Antifatigue effects of Panax ginseng C.A. Meyer: a randomised, double-blind, placebo-controlled trial. PLoS One. 2013;8(4):e61271.

1. Definition Disodium Edta:

Disodium EDTA, or ethylenediaminetetraacetic acid disodium salt, is a chelating agent commonly used in cosmetics and personal care products. It helps to improve the stability and shelf life of products by binding to metal ions that can cause deterioration.

2. Use:

Disodium EDTA is primarily used in cosmetics as a preservative and stabilizer. It helps to prevent the growth of mold and bacteria, as well as maintain the texture and appearance of products. Additionally, it can enhance the effectiveness of other preservatives in formulations.

3. Usage Disodium Edta:

Disodium EDTA is typically used in concentrations ranging from 0.1% to 0.5% in cosmetics. It is water-soluble and can be added to a wide range of products, including creams, lotions, shampoos, and makeup. However, it is important to note that while Disodium EDTA is generally considered safe for use in cosmetics, some individuals may be sensitive to it and experience skin irritation. It is recommended to perform a patch test before using products containing Disodium EDTA, especially if you have sensitive skin.

4. References:

- Cosmetic Ingredient Review (CIR) Expert Panel. (2002). Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. International Journal of Toxicology, 21(Suppl 2), 95-142.

- Personal Care Products Council. (2019). EDTA. Retrieved from https://www.personalcarecouncil.org/ingredient-info/edta/

- U.S. Food and Drug Administration (FDA). (2019). Code of Federal Regulations Title 21. Retrieved from https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1133